| 单词 | protease |
| 例句 | These supplements typically contain a variety of digestive enzymes such as amylases, lipases and proteases. Perspective | Why you should be wary of some digestive enzyme supplements 2019-02-18T05:00:00Z A breakthrough came in 1996 with the arrival of protease inhibitors, whose workings are clearly explained in a remarkable animated segment. Movie Review: ‘How to Survive a Plague,’ AIDS Documentary by David France 2012-09-20T23:56:55Z Chee chronicles their involvement with activist organizations like Act Up/SF and Queer Nation in the long years before the advent of protease inhibitors. Writing as Drag: Alexander Chee’s Essays Consider the Novelist’s Craft 2018-06-27T04:00:00Z The timing is pegged to when your body secretes hormones and enzymes like insulin, lipases and proteases. T Magazine: Get Stuffed 2011-11-10T18:40:07Z “Jewish or Chinese protease consensus sequences are not a thing in biochemistry, but they are in racism and antisemitism,” said Angela Rasmussen, a virologist at the University of Saskatchewan. Robert F. Kennedy Jr.’s Covid Remarks Raise Questions of Antisemitism 2023-07-15T04:00:00Z And over a few years, we developed a series of antiretroviral drugs, then we added the protease inhibitor. Fauci's warning to America: 'We're living in a progressively anti-science era and that's a very dangerous thing' 2022-12-22T05:00:00Z In the Avery, Macleod, and McCarty experiments, what conclusion would the scientists have drawn if the use of proteases prevented the transformation of R strain bacteria? Biology for AP Courses 2022-06-09T00:00:00Z The pancreas releases most of the digestive enzymes, including the proteases trypsin, chymotrypsin, and elastase, which aid protein digestion. Anatomy and Physiology 2013-06-19T00:00:00Z While drugs that initially seemed promising fell short, by the mid-90s, protease inhibitors slashed virus levels and delivered a medical miracle. F.D.A. Rushed a Drug for Preterm Births. Did It Put Speed Over Science? 2022-03-25T04:00:00Z It was just after the data on these protease inhibitors had been unveiled at a major scientific conference. Opinion | The Moral Danger of Declaring the Pandemic Over Too Soon 2022-02-17T05:00:00Z Paxlovid, known as a protease inhibitor, is designed to block an enzyme the virus needs in order to multiply. UK medicines regulator approves new Covid antiviral Paxlovid 2021-12-31T05:00:00Z A granzyme is a protease that digests cellular proteins and induces the target cell to undergo programmed cell death, or apoptosis. Biology for AP Courses 2022-06-09T00:00:00Z Molnupiravir works by introducing mutations to the virus, a different mechanism than in Pfizer’s pill, which interferes with a protease the virus needs to make copies of itself. FDA authorizes Merck’s anti-coronavirus pill, a second at-home treatment option 2021-12-23T05:00:00Z The second compound is another protease inhibitor called ritonavir. FDA greenlights Pfizer’s oral COVID-19 drug 2021-12-22T05:00:00Z The drug jams into one of Omicron’s crucial proteins — called a protease — just as effectively as it does with other variants, Pfizer found. Pfizer’s Covid Pill Works Well, Company Confirms in Final Analysis 2021-12-14T05:00:00Z It is part of a class of drugs called protease inhibitors currently used to treat HIV, hepatitis C and other viruses. Pfizer says COVID-19 pill near 90% effective in final analysis 2021-12-14T05:00:00Z AZT blocks the enzyme called HIV protease, which the virus uses to reproduce itself. Biology for AP Courses 2022-06-09T00:00:00Z They decided to build a molecule that could block an essential viral protein, known as a protease. New Covid Pills Offer Hope as Omicron Looms 2021-12-07T05:00:00Z Originally developed to tackle HIV’s protease, it also slows down metabolism of other drugs in the liver, allowing nirmatrelvir to remain in the body for longer periods of time. FDA greenlights Pfizer’s oral COVID-19 drug 2021-12-22T05:00:00Z Paxlovid, by contrast, is a protease inhibitor, much like those developed to combat HIV. How the New Antiviral Pills Help Thwart COVID 2021-12-01T05:00:00Z Another class, like Pfizer’s drug, could interfere with proteases, enzymes that the virus uses to process its proteins. Treatments will change the pandemic, but they can’t end it alone 2021-11-21T05:00:00Z AZT prevents reverse transcriptase and HIV protease enzyme from functioning inside the body. Biology for AP Courses 2022-06-09T00:00:00Z They modified it to work against the protease of the new coronavirus and tinkered with the molecule so it would work as a pill. New Covid Pills Offer Hope as Omicron Looms 2021-12-07T05:00:00Z The Pfizer antiviral is a protease inhibitor, a well-studied class of drugs that revolutionized the fight against HIV and have a known safety record. Pfizer antiviral slashes COVID-19 hospitalizations 2021-11-05T04:00:00Z That “polyprotein” must be chopped up into manageable bits by a viral enzyme called a protease. How the New Antiviral Pills Help Thwart COVID 2021-12-01T05:00:00Z Pfizer's drug, part of a class known as protease inhibitors, is designed to block an enzyme the coronavirus needs in order to multiply. Pfizer says antiviral pill cuts risk of severe COVID-19 by 89% 2021-11-05T04:00:00Z The Pfizer drug, known as a protease inhibitor, is designed to block an enzyme the virus needs in order to multiply. Covid: Pfizer says antiviral pill 89% effective in high risk cases 2021-11-05T04:00:00Z Our own cells make proteases, which we use to whittle down our own proteins, enabling them to perform new jobs. New Covid Pills Offer Hope as Omicron Looms 2021-12-07T05:00:00Z That was because, in tablet form, the protease inhibitor was metabolized too quickly, broken down by the body before it could effectively disable the virus, says a Pfizer spokesperson. Pfizer antiviral slashes COVID-19 hospitalizations 2021-11-05T04:00:00Z The oral therapy is a protease inhibitor, meaning it prevents the virus from replicating in the cell. Pfizer testing oral pill as COVID treatment 2021-03-25T04:00:00Z One line of attack that looks particularly promising is a group of drugs called protease inhibitors. Coronavirus: Virus provides leaps in scientific understanding 2021-01-09T05:00:00Z For example, researchers have high hopes for compounds that disrupt reproduction of the pandemic virus by inhibiting one of its two proteases. The science stories likely to make headlines in 2021 2020-12-31T05:00:00Z While many protease-inhibitor drugs have proved safe, some of them can also lock onto our proteases instead of the proteases made by viruses. New Covid Pills Offer Hope as Omicron Looms 2021-12-07T05:00:00Z Other drugs currently in clinical trials, such as the HIV drug lopinavir, are known as protease inhibitors and prevent the virus from breaking its proteins down into particles that spread through the body. For COVID Drugs, Months of Frantic Development Lead to Few Outright Successes 2020-11-13T05:00:00Z The next set of drugs was protease inhibitors, one of which I helped to develop. Lessons from AIDS for the COVID-19 Pandemic 2020-09-29T04:00:00Z Scientists have detailed the crystal structure of one of SARS-CoV-2’s key proteins, an enzyme called a protease that the virus needs to replicate within our cells. Coronavirus research updates: Trump’s favoured drug shows no benefit — but another drug does 2020-05-24T04:00:00Z The protease inhibitors and other compounds look promising in cell and animal studies. The science stories likely to make headlines in 2021 2020-12-31T05:00:00Z But, she added, “protease inhibitors have different liabilities.” New Covid Pills Offer Hope as Omicron Looms 2021-12-07T05:00:00Z Humans do not have a similar protease, so drugs targeting this protein are less likely to cause side effects. The sprint to solve coronavirus protein structures — and disarm them with drugs 2020-05-14T04:00:00Z That window is rather narrow for all polymerase and protease inhibitors. Lessons from AIDS for the COVID-19 Pandemic 2020-09-29T04:00:00Z These inhibitors work by infiltrating a hollow in the protease. Coronavirus research updates: Trump’s favoured drug shows no benefit — but another drug does 2020-05-24T04:00:00Z Enzymes called proteases to break up proteins in the sample. The scientists who made a 'home-brew' coronavirus test 2020-04-16T04:00:00Z Years later, pills that target H.I.V.’s proteases proved to be less toxic and more effective than AZT. New Covid Pills Offer Hope as Omicron Looms 2021-12-07T05:00:00Z In the United Kingdom, the Diamond team is screening various compounds against a second coronavirus protease. The sprint to solve coronavirus protein structures — and disarm them with drugs 2020-05-14T04:00:00Z These drugs inhibited the viral protease enzyme responsible for longer precursor proteins in the short active components of the virus. Lessons from AIDS for the COVID-19 Pandemic 2020-09-29T04:00:00Z The drug combination is what is known as a protease inhibitor, and it works by blocking an enzyme involved in viral replication. Here’s What We Know about the Most Touted Drugs Tested for COVID-19 2020-04-16T04:00:00Z A drug that blocks the main protease of one coronavirus is likely to work for another. How to help the free market fight coronavirus 2020-03-23T04:00:00Z Because lopinavir is quickly broken down in the human body by our own proteases, it is given with low levels of ritonavir, another protease inhibitor, that lets lopinavir persist longer. WHO launches global megatrial of the four most promising coronavirus treatments 2020-03-22T04:00:00Z These are chaperones, which aid protein folding, and proteases, which are enzymes that cleave proteins. Mitochondrial distress call moves to the cytosol to trigger a response to stress 2020-03-03T05:00:00Z Our bodies also use proteases for normal functioning, and we need polymerases to replicate our own nucleic acids. Lessons from AIDS for the COVID-19 Pandemic 2020-09-29T04:00:00Z The combination, known by the brand name Kaletra, appears to work to stop enzymes called proteases from allowing the virus to mature and replicate. Doctors fight coronavirus outbreak with drugs that target HIV, malaria and Ebola 2020-02-13T05:00:00Z The combination of drugs, known by the brand name Kaletra, appears to work to stop enzymes called proteases from allowing the virus to mature and replicate. To Fight Coronavirus Outbreak, Doctors Deploy Drugs Targeting HIV, Malaria And Ebola 2020-02-13T05:00:00Z The combination targets protease, an enzyme used by both HIV and coronaviruses to cut up proteins when they make new copies of themselves. Can an anti-HIV combination or other existing drugs outwit the new coronavirus? 2020-01-27T05:00:00Z Proteins are digested with enzymes known as proteases, and the digestions are put through a mass spectrometer. How Mass Spectrometry Can Help Limit Reproducibility Problems 2019-11-08T05:00:00Z It is quite possible that the proteases and polymerases encoded by the viruses of deep-sea organisms will offer researchers qualities different from those they have access to today. Classify viruses — the gain is worth the pain 2019-02-19T05:00:00Z As a second test case, they incorporated DAP into the active site of a cysteine protease enzyme, and showed that the inserted DAP indeed forms an acyl-enzyme intermediate that is resistant to hydrolysis. Enzymes engineered to trap reaction intermediates 2018-12-11T05:00:00Z Other researchers are using the glowing bacteria to develop a protease inhibitor to treat HIV and other diseases. 6 Medical Innovations That Moved from The Battlefield to Mainstream Medicine 2017-11-11T05:00:00Z Baric explains that proteins in the human body bind 99% of these protease inhibitors, leaving little of them to fight viruses. Can an anti-HIV combination or other existing drugs outwit the new coronavirus? 2020-01-27T05:00:00Z Signals that activate resistance traits, such as anti-digestive protease inhibitors, can be wafted on the wind or transmitted through the underground mycorrhizal networks, built by fungi, that connect plants. Plant science: The plant as pugilist : Nature : Nature Research 2017-02-28T05:00:00Z Some foods have compounds called proteases that help break down the protein, easing digestion when eating a heavy meal with meat. Get to Know Your Gut: 5 Essentials for Good Digestive Health 2016-04-27T04:00:00Z The researchers say theirs is the first such approach to specifically use the protease enzyme to guide imaging. New Imaging Technique 'Lights Up' Cancer Cells in Early Trial 2016-01-07T05:00:00Z As treatments advanced, including the major development of protease inhibitors in the 1990s, newer drugs attacked HIV-infected cells at a later point in their life cycle. Study explores healthy old age for those with HIV 2015-11-21T05:00:00Z The drugs target the reverse transcriptase and protease enzymes, which both viruses depend on, but differences exist between the HERV-K and HIV versions. Is an ancient virus responsible for some cases of Lou Gehrig’s disease? 2015-09-30T04:00:00Z They chose what looked like a promising target for treatment: an enzyme known as a protease that the virus depends on to make copies of itself. We Now Have the Cure for Hepatitis C, but Can We Afford It? 2014-09-04T04:00:00Z For instance, a regimen involving the antiviral Ribavirin, interferon and Incivek, a protease inhibitor, costs close to $80,000, according to Express Scripts, a pharmacy benefit manager that handles prescriptions for large parties. What Obamacare means for your investment portfolio Soaking the seeds also breaks down phytic acid and protease inhibitors, which allows the nutrients to be more readily absorbed by the body. Whole-Wheat Seeded Loaves 2014-06-02T04:00:00Z Aspartic acid residues at the intrinsic aspartyl protease site are coloured in dark blue. Mechanism of Tc toxin action revealed in molecular detail 2014-04-04T18:24:45.845Z In the early days of pregnancy, the primitive embryo — this rapidly dividing glob of cells — eats out a spot in the uterine lining using corrosive enzymes called proteases. Raw Data: A Tumor, the Embryo’s Evil Twin 2014-03-17T20:26:20Z Also, one class of antiretroviral drugs — protease inhibitors — tends to raise cholesterol levels. Global Health: Heart Problems Linked to Those Born With H.I.V. 2014-03-03T21:35:07Z Until late last year, the standard treatment for hepatitis C infection was a challenging 48-week regimen of weekly injections with interferon along with one or two oral antiviral drugs, ribavirin and a protease inhibitor. Well: Progress Against Hepatitis C, a Sneaky Virus 2014-02-24T05:01:20Z They took as their target the HIV protease molecule, which is critical in helping to build the viral particle, or virion, in a cell that will eventually break out to infect the next cell. Computers select personal medicine 2014-02-15T23:11:41Z Aspartic acid residues at the intrinsic aspartyl protease site are coloured in dark blue. Mechanism of Tc toxin action revealed in molecular detail 2014-04-04T18:24:45.845Z We show an anticoagulation therapy without bleeding risk based on a plasma protease factor XII function-neutralizing antibody. [Research Articles] A Factor XIIa Inhibitory Antibody Provides Thromboprotection in Extracorporeal Circulation Without Increasing Bleeding Risk 2014-02-05T19:55:07.288Z Current standard treatments for genotype 1 often include a protease inhibitor. FDA panel unanimously backs Gilead's hepatitis C drug sofosbuvir 2013-10-25T18:55:01Z The FDA advisory committee will also hear comment this week on Johnson & Johnson's application to sell simeprevir, an experimental protease inhibitor designed to target genotype 1 HCV. Preview - New wave of oral hepatitis C drugs near U.S. approval 2013-10-23T16:38:38Z Although the idea sounds simple, working out how each drug molecule would fit into the patient's shape-specific protease protein required enormous computing capability. Computers select personal medicine 2014-02-15T23:11:41Z Aspartic acid residues at the intrinsic aspartyl protease site are coloured in dark blue. Mechanism of Tc toxin action revealed in molecular detail 2014-04-04T18:24:45.845Z Oramed has introduced a protease inhibitor and another tweak designed to protect and enhance absorption of its oral insulin. Pharma's David and Goliath in race to produce insulin pill 2013-10-09T05:01:05Z How well does the gelatin solidify when using fruits that do not contain proteases? Solidifying Science: Why Can Certain Fruits Ruin Your Gelatin Dessert? 2013-07-25T14:15:00.660Z For this reason, the kids next added a few drops of protease to their tubes. Free Kits Help 10-Year-Olds See Their DNA 2013-02-15T00:45:02.933Z The protease has a slightly different shape in each individual, in particular in the protein's active zone where it slices the components that will form the next virion. Computers select personal medicine 2014-02-15T23:11:41Z In all forms of shock, blockade of digestive proteases with protease inhibitor attenuated entry of digestive enzymes into the wall of the intestine and subsequent autodigestion and morphological damage to the intestine, lung, and heart. [Research Articles] Pancreatic Digestive Enzyme Blockade in the Intestine Increases Survival After Experimental Shock 2013-01-23T19:55:07.367Z Senescent cells secrete a variety of signalling molecules such as cytokines and chemokines; proteins such as growth factors; and enzymes such as proteases. Stem cells: Repeat to fade 2012-12-06T12:21:18.613Z The fruits listed above contain proteases, which are enzymes. Solidifying Science: Why Can Certain Fruits Ruin Your Gelatin Dessert? 2013-07-25T14:15:00.660Z In addition to affecting the dough’s consistency, proteases affect its flavor. Enzymes: the little molecules that bake bread 2012-09-28T13:45:00.217Z A further breakthrough in treatment may come this year with the development of the experimental drug class called nucleotide polymerase inhibitors, which bind to a different part of the virus than the protease inhibitors. Boomers’ Drug Use Pushes Hepatitis Deaths Past HIV, Study Finds 2012-02-20T22:22:01Z Animals treated with protease inhibitors also survived in larger numbers than untreated controls over a period of 12 weeks. [Research Articles] Pancreatic Digestive Enzyme Blockade in the Intestine Increases Survival After Experimental Shock 2013-01-23T19:55:07.367Z All of the HIV drugs work by blocking protease, an enzyme the virus requires to replicate. Merck says hepatitis pill hampers HIV Drugs 2012-02-09T19:37:49Z Materials • One cup of one of the following types of fruit, which should contain proteases: figs, ginger root, guava, kiwi fruit, mango, papaya or pineapple. Solidifying Science: Why Can Certain Fruits Ruin Your Gelatin Dessert? 2013-07-25T14:15:00.660Z The other major enzyme at work in bread dough is protease. Enzymes: the little molecules that bake bread 2012-09-28T13:45:00.217Z “To our knowledge, no other protease inhibitor has shown this,” he said. Merck Gains on Boosting Dividend for First Time Since 2004 2011-11-11T15:32:14Z Protease inhibitors bind to the active part of a key protease, rendering it unable to cleave the polyprotein. Going Viral: New Hepatitis C Drugs Owe Their Success to HIV 2011-08-05T12:15:00.933Z The reduced prospects for Victrelis come even as its sales are being dwarfed by Vertex Pharmaceuticals Inc's Incivek, a rival protease inhibitor that was also approved last May. Merck says hepatitis pill hampers HIV Drugs 2012-02-09T19:37:49Z There are several different kinds of proteases in the fruits recommended for this activity, and using any of these fresh fruits should result in gelatin that does not solidify well, if at all. Solidifying Science: Why Can Certain Fruits Ruin Your Gelatin Dessert? 2013-07-25T14:15:00.660Z There are hundreds of proteases, but only a few are found in bread dough, where they chop the gluten into pieces. Enzymes: the little molecules that bake bread 2012-09-28T13:45:00.217Z Taken in combination with two other anti-HIV drugs, protease inhibitors work by halting the action of the protease enzyme, a protein produced by HIV that is necessary for replication of the virus. Key to HIV-Drug Resistance Found 2011-07-12T14:18:00Z And the conformational changes that underpin resistance to one protease inhibitor may also confer resistance to other inhibitors of that protease — a phenomenon called class resistance. Perspective: Recognizing resistance 2011-06-13T13:20:36.973Z A major caveat of the protease inhibitors, however, is that they must be used in combination with the existing standard of care. Perspective: Miles to go before we sleep 2011-06-13T13:20:34.157Z “This one would be a good partner for a protease inhibitor,” says Pockros. Therapeutics: New drugs hit the target 2011-06-13T13:20:32.767Z Eventually someone thought to look at protease activity in normal bread dough and found very little activity. Enzymes: the little molecules that bake bread 2012-09-28T13:45:00.217Z Currently there are nine FDA approved protease inhibitors, and 21 most common drug-resistant mutations. Key to HIV-Drug Resistance Found 2011-07-12T14:18:00Z But protease inhibitors, available since 1996, are expensive and are thus not available to most of the afflicted. 30 years after AIDS' discovery, medical and behavioral challenges remain 2011-06-05T00:44:43Z Boceprevir works by blocking the enzyme protease that helps hepatitis reproduce. FDA weighs new dose info for kids' pain relievers 2011-05-14T00:30:00Z Inc. Both new drugs work by blocking the enzyme protease, which allows the hepatitis virus to reproduce. FDA says Vertex hepatitis drug is highly effective 2011-04-26T20:16:04Z Too much protease activity would break up the gluten, destroying the network that forms during kneading. Enzymes: the little molecules that bake bread 2012-09-28T13:45:00.217Z However, almost half of HIV patients who initially respond to treatment with protease inhibitors develop drug-resistance strains and stop responding to treatment within eight to 10 months. Key to HIV-Drug Resistance Found 2011-07-12T14:18:00Z Separate clinical trials on boceprevir and telaprevir showed both drugs, so-called protease inhibitors, cured more patients when used with approved treatments. Merck Wins U.S. FDA Panel’s Backing for Hepatitis C Drug 2011-04-27T20:23:04Z Both of the new medicines work by blocking a protein called protease that the virus needs to replicate. FDA backs Vertex hepatitis drug efficacy, shares jump 2011-04-26T18:46:05Z Both new drugs work by blocking the enzyme protease, which allows the hepatitis virus to reproduce. FDA says Vertex hepatitis drug is highly effective 2011-04-26T15:30:09Z These substrates were ones that protease readily attacks. Enzymes: the little molecules that bake bread 2012-09-28T13:45:00.217Z Eventually, these were joined by a new generation of drugs known as protease inhibitors. W. H. Prusoff, Who Developed AIDS Drug, Is Dead at 90 2011-04-07T02:55:44Z Both compounds are protease inhibitors and are expected to hit the market at about the same time. New Drugs for Hepatitis C On the Horizon 2011-03-30T21:45:00.247Z The growth advantage conferred by sequestration of the protease was used to drive directed evolution within bacterial cell cultures, resulting in capsids with 5 to 10 times higher protease loading capacities. This Week in Science 2011-02-03T19:25:00.683Z These drugs target the HCV protease—one of the virus's enzymes. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z They amplified the protease activity by adding non-gluten substrates to the mix. Enzymes: the little molecules that bake bread 2012-09-28T13:45:00.217Z The research, published this month in the Journal of Biological Chemistry, shows HIV protease inhibitor drugs directly interfere with the way blood sugar levels are controlled in the body. Researchers say uncover HIV, insulin resistance link 2010-11-23T23:19:00Z Early studies showed that although a protease inhibitor given on its own was very effective initially, it often led to resistant strains of the virus in a matter of days, Gordon says. New Drugs for Hepatitis C On the Horizon 2011-03-30T21:45:00.247Z Certain tumors are protease factories, Gracias says, raising the possibility that minimachines might be designed to trigger automatically upon reaching diseased tissue. Tiny Tools Aren?t Toys 2010-09-27T15:54:00Z Lab strains of HCV that harbor mutations crippling the protease fail to replicate in cells in a petri dish and cannot establish an infection in chimpanzees, the animal model for studying HCV. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z “Gamma secretase belongs to a family of proteins called proteases,” he explained. Finding Suggests New Target for Alzheimer?s Drugs 2010-09-01T18:27:00Z Munching caterpillars produce oral secretions that “activate a whole series of defense responses,” Dr. Baldwin said, including the production of toxins and protease inhibitors that decrease the caterpillars’ digestive ability. 2010-01-22T07:22:00Z The best-known example of this type of enzymes is the protease of yeast; but similar ones may be found in germinating seeds. The Chemistry of Plant Life Along with cleaving the viral polyproteins, which benefits the virus, the HCV protease also cleaves cellular proteins involved in the immune response, which may compromise patient immunity. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z Because of the importance of the HCV protease, scientists at Vertex and Schering designed small molecules, based on the structure of the protease protein, that could fit into the protease's active site. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z And, if a protease inhibitor were added in the treatment mix, it could prevent some of the destruction of the host's immune response. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z As is the problem with any drug that targets an HCV protein, viruses have emerged that are resistant to protease inhibitors. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z This phenomenon has been studied in connection with the zymogens of the digestive proteases, pepsin and trypsin. The Chemistry of Plant Life Because patients harbor a heterogeneous mix of HCV species, there could easily be a few in the population that are able to grow despite protease inhibitors, causing a so-called "viral breakthrough". Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z But there could be some overlap between the action of the protease inhibitors and that of interferon. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z The protease inhibitors could be just the beginning of anti-HCV drugs that are added to the treatment regime. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z Compounds that inhibit the HCV polymerase are currently in phase II trials and, if all goes well, could get to market about a year after protease inhibitors. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z |
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