| 单词 | poliovirus |
| 例句 | If the vaccine worked, the serum from a vaccinated child’s blood would block the poliovirus and protect the cells. The Immortal Life of Henrietta Lacks 2010-02-02T00:00:00Z Second, cells often behave differently, even if they’re all from the same sample, which means some grow faster than others, some produce more poliovirus, and some are resistant to certain antibiotics. The Immortal Life of Henrietta Lacks 2010-02-02T00:00:00Z This discovery meant that if HeLa was susceptible to poliovirus, which not all cells were, it would solve the mass-production problem and make it possible to test the vaccine without millions of monkey cells. The Immortal Life of Henrietta Lacks 2010-02-02T00:00:00Z But doing this would require millions of neutralization tests, which involved mixing blood serum from newly vaccinated children with live poliovirus and cells in culture. The Immortal Life of Henrietta Lacks 2010-02-02T00:00:00Z If it is able to circulate for some considerable time, it can mutate to a strain capable of causing disease, called a circulating vaccine-derived poliovirus. Polio in two Ukrainian children first occurrence of disease in Europe since 2010 2015-09-02T04:00:00Z Related: Ukrainian guardsman killed in protests against vote on rebel autonomy But blitzing the handful of countries where wild poliovirus is still infecting children has absorbed a lot of the vaccine manufacturers’ capacity. Polio in two Ukrainian children first occurrence of disease in Europe since 2010 2015-09-02T04:00:00Z In 1955 Salk won the race to develop an effective polio vaccine, using a version containing poliovirus killed by chemicals. The lifesaver 2015-06-25T04:00:00Z There are two countries, Afghanistan and Pakistan, where wild poliovirus still circulates. World Polio Day: Immunizations are key 2023-10-20T04:00:00Z Only two countries, Afghanistan and Pakistan, continue to have cases of paralysis caused by wild poliovirus, with only seven documented this year up to 12 September. Global polio eradication effort struggles with the end game 2023-09-18T04:00:00Z Wiping out wild poliovirus, of which there are three strains, termed serotypes 1, 2 and 3, has been the goal of global eradication efforts since they began in 1988. Getting Closer to Eliminating the Wild Poliovirus 2023-08-21T04:00:00Z The original or "wild" poliovirus is now contained to small pockets of Afghanistan and Pakistan and the oral vaccines play a pivotal role in the attempt to rid the world of polio. Super-engineered vaccines created to help end polio 2023-06-14T04:00:00Z But poliovirus traces were found in north and east London sewage in early 2022. Polio vaccine catch-up push to launch in London 2023-03-23T04:00:00Z This happens most often with poliovirus type 2, one of three serotypes. First polio cases linked to new oral vaccine detected in Africa 2023-03-19T04:00:00Z The first polio vaccine, which went into use in 1955, was a shot containing inactivated polioviruses, and although it protected people from paralytic disease, it did little to stop poliovirus transmission. Global polio eradication effort struggles with the end game 2023-09-18T04:00:00Z But only one genetic cluster of wild poliovirus type 1 is currently present in each country — down from 11 in Pakistan and 8 in Afghanistan in 2020. Getting Closer to Eliminating the Wild Poliovirus 2023-08-21T04:00:00Z There are now more cases of "vaccine-derived polio" than of the wild poliovirus and the polio detected in London's sewers last year was connected to the oral vaccine. Super-engineered vaccines created to help end polio 2023-06-14T04:00:00Z Five other samples from environmental surveillance of waste water confirmed the presence of circulating poliovirus type 2 in Burundi, the WHO added in a statement. Vaccine-derived poliovirus detected in Burundi, Congo 2023-03-17T04:00:00Z More recently, in November 2022, poliovirus was found in the wastewater of a lab in the Netherlands that conducted research on polio. Opinion | The Checkup With Dr. Wen: What does it mean to hold China ‘accountable’ for covid? 2023-03-02T05:00:00Z But because of the potential for rare cases of vaccine-derived poliovirus, many countries—including the United States—returned to IPV after they eliminated polio. Global polio eradication effort struggles with the end game 2023-09-18T04:00:00Z Molodecky says for every child paralysed with wild poliovirus type 1, there are about 200 asymptomatic infections. Getting Closer to Eliminating the Wild Poliovirus 2023-08-21T04:00:00Z There was now a "unique opportunity" to eradicate wild poliovirus - but vaccine-derived polio outbreaks were causing problems in places facing "complex humanitarian emergencies", in the Democratic Republic of Congo and Yemen. Super-engineered vaccines created to help end polio 2023-06-14T04:00:00Z Circulating poliovirus type 2 is different to wild poliovirus, with infections occurring when a weakened strain of poliovirus contained in the oral polio vaccine circulates among under-immunized populations for long periods. Vaccine-derived poliovirus detected in Burundi, Congo 2023-03-17T04:00:00Z Afghanistan and its neighbor Pakistan are the last two countries where the wild poliovirus is still endemic, and the campaign is going full bore to wipe it out by the end of 2023. Taliban ban on female NGO staff is deepening Afghanistan’s public health crisis 2023-01-15T05:00:00Z The eradication campaign originally relied on a “trivalent” OPV against the three poliovirus types. Global polio eradication effort struggles with the end game 2023-09-18T04:00:00Z Attaullah Ahmadi, a public-health researcher at Kabul University of Medical Sciences in Afghanistan, agrees that the epidemiological evidence suggests Afghanistan and Pakistan are “on the brink of eradicating the wild poliovirus”. Getting Closer to Eliminating the Wild Poliovirus 2023-08-21T04:00:00Z Evidence of expanding community spread has landed the United States on a list of more than 30 countries with active circulation of a type of polio known as vaccine-derived poliovirus. CDC expands wastewater testing for polio to Michigan and Pennsylvania 2022-11-30T05:00:00Z The strategic use of testing, which is expected to last at least four months once initiated, can help determine if poliovirus is present in other parts of the country. U.S. CDC to expand wastewater testing for poliovirus in some communities 2022-11-30T05:00:00Z With just two cases caused by the wild poliovirus in Afghanistan in 2022, they say they have no intention of letting up. Taliban ban on female NGO staff is deepening Afghanistan’s public health crisis 2023-01-15T05:00:00Z It’s a remarkable accomplishment that we have a safer vaccine for type 2 poliovirus. Global polio eradication effort struggles with the end game 2023-09-18T04:00:00Z Injectable, inactivated poliovirus vaccines are not known to cause or seed paralysis cases, but they do not contain polio outbreaks as effectively as OPVs. Getting Closer to Eliminating the Wild Poliovirus 2023-08-21T04:00:00Z “Wastewater testing can be an important tool to help us understand if poliovirus may be circulating in communities in certain circumstances,” Romero said. CDC expands wastewater testing for polio to Michigan and Pennsylvania 2022-11-30T05:00:00Z Detection of poliovirus in sewage or wastewater indicates someone in the community is shedding the virus. U.S. CDC to expand wastewater testing for poliovirus in some communities 2022-11-30T05:00:00Z The World Health Assembly adopted a resolution for the global eradication of polio in 1988 and since then, wild poliovirus cases have decreased by more than 99%, according to the World Health Organization. Polio is back in Indonesia, sparking vaccination campaign 2022-11-28T05:00:00Z “But this one seems pretty urgent. It is a bit ironic that now we have some poliovirus being sampled in environmental samples, not only in London, but also in New York City.” Gates pledges $1.2 billion to speed end of crippling poliovirus 2022-10-16T04:00:00Z “This is the best epidemiological opportunity these two countries have had concurrently,” to stop wild poliovirus from circulating, says Hamid Jafari, director of polio eradication at the WHO. Getting Closer to Eliminating the Wild Poliovirus 2023-08-21T04:00:00Z The Michigan and Philadelphia health departments are working with the CDC to identify communities that are under-vaccinated for poliovirus and have wastewater sampling locations. CDC expands wastewater testing for polio to Michigan and Pennsylvania 2022-11-30T05:00:00Z Experts agree that a vaccinated population is the best defense against poliomyelitis, the technical name for the disease caused by the poliovirus—which can sometimes lead to permanent paralysis. Everything You Need to Know about Polio in the U.S. 2022-09-29T04:00:00Z Polio is short for "poliomyelitis," a neurological disease caused by a poliovirus infection. With Polio’s Return, Here’s What Back-to-Schoolers Need to Know 2022-09-20T04:00:00Z From that tenacious stronghold, the wild poliovirus has spread back into southeastern Africa. Gates pledges $1.2 billion to speed end of crippling poliovirus 2022-10-16T04:00:00Z An analysis of polio transmission dynamics, published in 2020, found that global polio eradication efforts were “not on track to succeed” in their goal of eliminating wild poliovirus type 1 by 2023. Getting Closer to Eliminating the Wild Poliovirus 2023-08-21T04:00:00Z Both the wild poliovirus and the live, weakened OPV viruses can cause infection. With polio’s return, here’s what back-to-schoolers need to know 2022-09-19T04:00:00Z The type of poliovirus now circulating in the U.S. complicates polio eradication here and reflects the history of vaccination against the condition. Everything You Need to Know about Polio in the U.S. 2022-09-29T04:00:00Z Of the three types of wild poliovirus — serotypes 1, 2, and 3 — serotype 1 is the most virulent and the most likely to cause paralysis. With Polio’s Return, Here’s What Back-to-Schoolers Need to Know 2022-09-20T04:00:00Z In recent months, floods inundated a third of the country, displacing millions of people and fanning the spread of poliovirus. Gates pledges $1.2 billion to speed end of crippling poliovirus 2022-10-16T04:00:00Z Fears that eradication was falling out of reach increased again in 2021, when wild poliovirus broke containment lines and emerged in eastern Africa. Getting Closer to Eliminating the Wild Poliovirus 2023-08-21T04:00:00Z Because IPV is a killed virus vaccine, it cannot infect or replicate, give rise to vaccine-derived poliovirus, or cause paralytic poliomyelitis disease. With polio’s return, here’s what back-to-schoolers need to know 2022-09-19T04:00:00Z Vaccine-derived poliovirus can crop up in the U.S. if travelers pick it up elsewhere and bring it back to the country. Everything You Need to Know about Polio in the U.S. 2022-09-29T04:00:00Z Most people infected with poliovirus don't get sick and won't have symptoms. With Polio’s Return, Here’s What Back-to-Schoolers Need to Know 2022-09-20T04:00:00Z Polio, known medically as poliomyelitis, is a highly infectious disease caused by one of three poliovirus types that replicate in the human gastrointestinal tract. Gates pledges $1.2 billion to speed end of crippling poliovirus 2022-10-16T04:00:00Z There are also over 100 different strains of enteroviruses, including poliovirus, the pathogen famously responsible for polio, a disease notorious for paralyzing its victims. A polio-like virus is infecting children. Here's what we know, and how to avoid it 2022-09-14T04:00:00Z Today, poliovirus is most likely to spread where hygiene and sanitation are poor and vaccination rates are low. With polio’s return, here’s what back-to-schoolers need to know 2022-09-19T04:00:00Z Two weeks ago the U.S. achieved the dubious distinction of joining the World Health Organization’s list of countries with circulating vaccine-derived poliovirus. Everything You Need to Know about Polio in the U.S. 2022-09-29T04:00:00Z People with mild poliovirus infection don't require treatment. With Polio’s Return, Here’s What Back-to-Schoolers Need to Know 2022-09-20T04:00:00Z That vaccine, developed by Albert Sabin, uses a live, attenuated form of the poliovirus. Gates pledges $1.2 billion to speed end of crippling poliovirus 2022-10-16T04:00:00Z The poliovirus spreads easily through fecal-oral contact and thrives in places where sanitation is lacking and clean water scarce. Polio is back rich countries, but it poses a far bigger threat to developing world 2022-09-13T04:00:00Z The CDC has since started to monitor wastewater for poliovirus. With polio’s return, here’s what back-to-schoolers need to know 2022-09-19T04:00:00Z No cases involving wild poliovirus have originated in the U.S. since 1979, according to the CDC, and there have been no cases related to wild poliovirus in the country at all since 1993. Everything You Need to Know about Polio in the U.S. 2022-09-29T04:00:00Z Health officials say wastewater samples in New York City and four adjacent counties have tested positive for a poliovirus that can cause paralysis. New York declares state of emergency over polio 2022-09-09T04:00:00Z Most cases globally are caused by a derivative of the oral vaccine for the type-2 poliovirus. Gates pledges $1.2 billion to speed end of crippling poliovirus 2022-10-16T04:00:00Z Cases caused by the wild poliovirus are also up: Pakistan has already reported 17 this year, up from one in all of 2021. Polio is back rich countries, but it poses a far bigger threat to developing world 2022-09-13T04:00:00Z Unrelated vaccine-derived poliovirus has also been detected in New York City wastewater. With polio’s return, here’s what back-to-schoolers need to know 2022-09-19T04:00:00Z Thanks to decades of successful vaccination campaigns, wild poliovirus cases dropped from hundreds of thousands worldwide in 1988 to only six in 2021, according to the WHO. Everything You Need to Know about Polio in the U.S. 2022-09-29T04:00:00Z The poliovirus had previously been detected in wastewater in New York City and three counties to its north: Rockland, Orange and Sullivan. Poliovirus detected in more wastewater near New York City 2022-09-09T04:00:00Z The discovery of poliovirus in New York state, London and Jerusalem this year has taken many by surprise — but public-health researchers fighting to eradicate the disease say it was only a matter of time. New Polio Outbreaks Worldwide Put Scientists on Alert 2022-08-25T04:00:00Z Isometric viruses have shapes that are roughly spherical, such as poliovirus or herpesviruses. Biology for AP Courses 2022-06-09T00:00:00Z A: People with mild poliovirus infection don’t require treatment. With polio’s return, here’s what back-to-schoolers need to know 2022-09-19T04:00:00Z The two countries have reported 21 cases of wild poliovirus so far in 2022. Everything You Need to Know about Polio in the U.S. 2022-09-29T04:00:00Z Wild poliovirus is the most commonly known form. Polio: What is it and how does it spread? 2022-08-10T04:00:00Z If, in six months or so, wastewater testing suggests that poliovirus has continued to spread, it might be necessary to look at other options, he says. New Polio Outbreaks Worldwide Put Scientists on Alert 2022-08-25T04:00:00Z But poliovirus was found in sewage samples, not tap water, and people cannot contract polio by drinking the city’s tap water, multiple city and state officials said. NOT REAL NEWS: A look at what didn’t happen this week 2022-08-19T04:00:00Z Wild poliovirus serotype 1, the most virulent form, remains endemic only in Pakistan and Afghanistan, but vaccine-derived polioviruses continue to circulate in some countries in Africa and other parts of the world. With polio’s return, here’s what back-to-schoolers need to know 2022-09-19T04:00:00Z For most people in the U.S., even in New York, the risk of contracting vaccine-derived poliovirus is low. Everything You Need to Know about Polio in the U.S. 2022-09-29T04:00:00Z The poliovirus has been eliminated in the U.S. and most countries for decades; the infected person is believed to have caught the virus from an international traveler. First U.S. Polio Case in Nearly a Decade Highlights the Importance of Vaccination 2022-08-19T04:00:00Z Wild poliovirus circulates in only two countries — Afghanistan and Pakistan — where this year nine cases had been reported by June. New Polio Outbreaks Worldwide Put Scientists on Alert 2022-08-25T04:00:00Z Wastewater — used water from toilets, sinks, showers and household appliances — does not come in contact with the city’s drinking water, she said, adding there are no plans to test tap water for poliovirus. NOT REAL NEWS: A look at what didn’t happen this week 2022-08-19T04:00:00Z A: Polio is short for “poliomyelitis,” a neurological disease caused by a poliovirus infection. With polio’s return, here’s what back-to-schoolers need to know 2022-09-19T04:00:00Z People who get infected with poliovirus in adolescence or later tend to fare worse than babies do, Maldonado and Adalja say, which is another reason to vaccinate early and get protection in place. Everything You Need to Know about Polio in the U.S. 2022-09-29T04:00:00Z Nevertheless, people who have received this injectable vaccine can still acquire and carry the poliovirus and spread it to others, despite having no symptoms themselves. First U.S. Polio Case in Nearly a Decade Highlights the Importance of Vaccination 2022-08-19T04:00:00Z But vaccine-derived poliovirus appears periodically elsewhere, particularly in Africa and Asia. New Polio Outbreaks Worldwide Put Scientists on Alert 2022-08-25T04:00:00Z The state Department of Health began monitoring wastewater for signs of poliovirus through repeated sampling after a Rockland County, New York, resident developed paralysis as a result of poliovirus earlier this summer, Fuld said. NOT REAL NEWS: A look at what didn’t happen this week 2022-08-19T04:00:00Z Of the three types of wild poliovirus — serotypes 1, 2 and 3 — serotype 1 is the most virulent and the most likely to cause paralysis. With polio’s return, here’s what back-to-schoolers need to know 2022-09-19T04:00:00Z At these rates, vaccine-derived poliovirus will hit a wall of immunity in most of the country. Everything You Need to Know about Polio in the U.S. 2022-09-29T04:00:00Z But when relatively few people are vaccinated, the poliovirus in the oral vaccine has a chance to evolve back into a relatively normal virus—and to spread like one. First U.S. Polio Case in Nearly a Decade Highlights the Importance of Vaccination 2022-08-19T04:00:00Z Pakistan, one of only two countries where wild poliovirus still circulates, had not recorded cases in more than a year. Polio Was Almost Eradicated. This Year It Staged a Comeback. 2022-08-18T04:00:00Z According to the state agency, the CDC has confirmed the presence of poliovirus in sewage samples from New York City, Rockland County and New York’s Orange County. NOT REAL NEWS: A look at what didn’t happen this week 2022-08-19T04:00:00Z Most people infected with poliovirus don’t get sick and won’t have symptoms. With polio’s return, here’s what back-to-schoolers need to know 2022-09-19T04:00:00Z New York is continuing to monitor wastewater samples for poliovirus. Everything You Need to Know about Polio in the U.S. 2022-09-29T04:00:00Z In addition, poliovirus has been found in wastewater in Rockland County and nearby Orange County, including in a sample taken in April. Opinion | The reemergence of polio is a public health emergency. And a tragedy. 2022-08-17T04:00:00Z There are three strains of the wild poliovirus. Polio Was Almost Eradicated. This Year It Staged a Comeback. 2022-08-18T04:00:00Z On Aug. 12, health officials announced that poliovirus had been detected in sewage samples in New York City, indicating that the virus is likely circulating there too. Polio Symptoms and Prevention: What to Know 2022-08-04T04:00:00Z But in up to 1 in 200 people with a poliovirus infection, the virus may attack the spinal cord and brain. With polio’s return, here’s what back-to-schoolers need to know 2022-09-19T04:00:00Z “The detection of poliovirus in wastewater samples in New York City is alarming,” Dr. Mary T. Bassett, the New York State Health Commissioner, said in a statement. First U.S. polio case in years sparks alarms from New York to California 2022-08-13T04:00:00Z Health departments identified one case of vaccine-derived poliovirus in Rockland County, New York, last month but the samples suggest the virus could be pinging around the Big Apple, too. NYC officials detect polio in wastewater, urge vaccination 2022-08-12T04:00:00Z Only Type 1 poliovirus remains at large, and only in Pakistan and Afghanistan. Polio Was Almost Eradicated. This Year It Staged a Comeback. 2022-08-18T04:00:00Z These occurrences, as well as reports that health officials in Britain had detected evidence of poliovirus in sewage samples in London, have reignited polio concerns. Polio Symptoms and Prevention: What to Know 2022-08-04T04:00:00Z Rarely, poliovirus may spread through saliva and upper respiratory droplets. With polio’s return, here’s what back-to-schoolers need to know 2022-09-19T04:00:00Z The presence of the poliovirus in the city’s wastewater suggests likely local circulation of the virus, the city and New York state health departments said. Polio detected in NYC’s sewage, suggesting virus circulating 2022-08-12T04:00:00Z “The detection of poliovirus in wastewater samples in New York City is alarming, but not surprising.” NYC officials detect polio in wastewater, urge vaccination 2022-08-12T04:00:00Z Britain will offer a polio booster vaccine dose to children ages 1 to 9 in London, after the poliovirus was detected in wastewater in parts of the city. London children offered polio vaccine booster as virus found in wastewater 2022-08-11T04:00:00Z Polio, also known as poliomyelitis, is a sometimes disabling and life-threatening disease caused by the poliovirus. Polio Symptoms and Prevention: What to Know 2022-08-04T04:00:00Z “There are a number of individuals in the community that have been infected with poliovirus. They are shedding the virus,” he told CNN. CDC growing concerned about evidence of polio in N.Y. county 2022-08-11T04:00:00Z State Health Commissioner Dr. Mary T. Bassett said the detection of poliovirus in wastewater samples in New York City is alarming but not surprising. Polio detected in NYC’s sewage, suggesting virus circulating 2022-08-12T04:00:00Z Health Security Agency said in a statement, but between February and July, 116 samples of type 2 poliovirus were detected in samples from eight London boroughs in the north and east of the city. London Children Offered Polio Vaccine Booster as More Virus Is Found in Sewage 2022-08-10T04:00:00Z Since early February, 116 instances of poliovirus had been identified in 19 wastewater samples from areas in northeast and central London. London children offered polio vaccine booster as virus found in wastewater 2022-08-11T04:00:00Z The oral polio vaccine, which helped the United States eliminate polio and is not administered in the country anymore, contains weakened live poliovirus. Polio Symptoms and Prevention: What to Know 2022-08-04T04:00:00Z “We know the areas in London where the poliovirus is being transmitted have some of the lowest vaccination rates,” said Dr. Vanessa Saliba, a consultant epidemiologist at the U.K. London kids to be offered polio shot after more virus found 2022-08-10T04:00:00Z Since 1979, there has not been a single case of wild poliovirus that has originated in the United States. Could a polio epidemic really happen again? Outbreaks in New York state raise alarm 2022-08-09T04:00:00Z Wild poliovirus has been eliminated from every country in the world except Afghanistan and Pakistan. London Children Offered Polio Vaccine Booster as More Virus Is Found in Sewage 2022-08-10T04:00:00Z It has one drawback, which Sabin, who died in 1993, fiercely disputed: In rare cases, the weakened live poliovirus in the vaccine can mutate, regain virulence, and cause polio. What the Polio Case in New York Tells Us About the End of Polio 2022-08-03T04:00:00Z There are many countries that still use the oral vaccine, because it is safe and effective at stopping person-to-person transmission of the poliovirus. Polio Symptoms and Prevention: What to Know 2022-08-04T04:00:00Z Type 2 vaccine-derived poliovirus is the kind that was found in the British sewage samples. “Reactive strategy”: How polio crept back into the U.S. 2022-07-27T04:00:00Z The oral vaccine uses a live weakened version of the poliovirus. Could a polio epidemic really happen again? Outbreaks in New York state raise alarm 2022-08-09T04:00:00Z Thanks to global vaccination campaigns, polio is now almost eradicated, with only 13 cases of endemic wild poliovirus reported in 2022 to date worldwide. New York Polio Case Revives Questions About Live Oral Vaccine 2022-07-25T04:00:00Z Scientists have detected poliovirus in county wastewater but have no idea how many others are infected, Cefalu said in a news release July 26. What the Polio Case in New York Tells Us About the End of Polio 2022-08-03T04:00:00Z This includes people who live in areas where poliovirus has been detected in wastewater samples, like in New York City and other parts of New York State. Polio Symptoms and Prevention: What to Know 2022-08-04T04:00:00Z Inactivated poliovirus vaccine, or IPV, is given as an injection in the leg or arm, depending on the patient’s age. Unvaccinated man in Rockland County, N.Y., diagnosed with polio 2022-07-21T04:00:00Z This hints that the poliovirus in question did not originate in the United States, although it is not certain. Could a polio epidemic really happen again? Outbreaks in New York state raise alarm 2022-08-09T04:00:00Z The New York patient reportedly contracted a form of polio that can be traced back to the live, but weakened, poliovirus used in the oral polio vaccine. New York Polio Case Revives Questions About Live Oral Vaccine 2022-07-25T04:00:00Z Officials in the United Kingdom declared a “national incident” last week after poliovirus was detected in samples taken between February and June from one of London’s main sewage treatment plants. News at a glance: Polio in London sewage, U.S. science spending bills, and new medical citations leader 2022-06-29T04:00:00Z It's estimated that 6.5 million children would have been paralysed by wild poliovirus in the last decade without the oral vaccine. Polio: Virus found in London prompts misleading vaccine claims 2022-06-24T04:00:00Z Oral poliovirus vaccine, or OPV, is still used throughout much of the world. Unvaccinated man in Rockland County, N.Y., diagnosed with polio 2022-07-21T04:00:00Z This type of poliovirus, known as Type 2, paralyzes as few as 1 in 1,000 of the people who get it. Could a polio epidemic really happen again? Outbreaks in New York state raise alarm 2022-08-09T04:00:00Z Apparently, the current patient in New York was somehow exposed to a mutated poliovirus that had been transmitted after vaccination overseas. New York Polio Case Revives Questions About Live Oral Vaccine 2022-07-25T04:00:00Z The type 2 vaccine-derived poliovirus — as opposed to the wild or naturally occurring strain — is a weakened form of the live virus used in oral polio vaccines. Traces of highly contagious poliovirus found in British sewage 2022-06-23T04:00:00Z On 7 March, an unvaccinated 3-year-old in Israel who had developed paralysis was diagnosed with polio, and the country has detected poliovirus in 25 sewage samples so far this year, mostly in or near Jerusalem. Poliovirus in London sewage sparks alarm 2022-06-23T04:00:00Z OPV is no longer authorized or administered in the United States because of its potential to cause vaccine-derived poliovirus. Unvaccinated man in Rockland County, N.Y., diagnosed with polio 2022-07-21T04:00:00Z A strain of poliovirus that can sometimes cause paralysis has cropped up in the sewers of London and may be spreading among closely-linked individuals in the north and east regions of the city, the U.K. Poliovirus Detected in London Sewage, UK Officials Warn 2022-06-23T04:00:00Z Here he explains what vaccine-derived poliovirus is and why the inactivated polio vaccine administered in the U.S. today can’t cause it. New York Polio Case Revives Questions About Live Oral Vaccine 2022-07-25T04:00:00Z The vaccine-derived poliovirus detected in the U.K. “on rare occasions can cause serious illness, such as paralysis, in people who are not fully vaccinated,” the British health authorities said. Traces of highly contagious poliovirus found in British sewage 2022-06-23T04:00:00Z The OPV that brought the virus to both the United Kingdom and Israel has advantages in regions where poliovirus is spreading. Poliovirus in London sewage sparks alarm 2022-06-23T04:00:00Z In June, the United Kingdom Health Security Agency reported finding poliovirus in sewage samples collected from the largest treatment plant in the United Kingdom, the first time a likely outbreak has been identified in London. Unvaccinated man in Rockland County, N.Y., diagnosed with polio 2022-07-21T04:00:00Z The presence of VDPV2 hints that the poliovirus may be spreading among “closely-linked individuals in North and East London,” who are now shedding virus in their stool, the statement reads. Poliovirus Detected in London Sewage, UK Officials Warn 2022-06-23T04:00:00Z The oral polio vaccine, originally developed by Albert Sabin, uses a live but weakened poliovirus that one swallows in a sugar cube or droplet. New York Polio Case Revives Questions About Live Oral Vaccine 2022-07-25T04:00:00Z So far, the poliovirus has only been detected in sewage samples but investigations are underway to establish whether any community transmission is occurring. Traces of highly contagious poliovirus found in British sewage 2022-06-23T04:00:00Z In the same period, in the absence of vaccination with the oral polio vaccine, more than 6.5 million children would have been paralysed by wild poliovirus. Polio: What is it and how does it spread? 2022-06-23T04:00:00Z Britain declared a national incident after finding evidence suggesting local spread of poliovirus in London, although no cases have been identified so far. Your Thursday Briefing 2022-06-23T04:00:00Z Health authorities in Britain have declared a national incident after finding evidence suggesting local spread of poliovirus in London. Britain Declares National Incident After Poliovirus Found in London 2022-06-22T04:00:00Z Earlier this summer, routine surveillance spotted vaccine-derived poliovirus in London’s sewage system, but no cases have been reported there. New York Polio Case Revives Questions About Live Oral Vaccine 2022-07-25T04:00:00Z “Vaccine-derived poliovirus is rare and the risk to the public overall is extremely low,” Vanessa Saliba, consultant epidemiologist at UK Health Security Agency, said in a statement. Traces of highly contagious poliovirus found in British sewage 2022-06-23T04:00:00Z The notion of that there is a sort of interplay between viruses first emerged in the 1960s, when vaccinations for polio, which contain weakened poliovirus, significantly cut the number of respiratory infections. Why a Coronavirus-Flu ‘Twindemic’ May Never Happen 2022-04-08T04:00:00Z It is hard to tell when the threat has abated, because most people infected with poliovirus show no symptoms, but can still spread it for weeks or months. Chaos of War in Ukraine Could Fuel New Covid Surge, Doctors Say 2022-03-12T05:00:00Z But health authorities urged anyone who is not fully immunized against poliovirus, particularly young children, to immediately seek vaccines. Britain Declares National Incident After Poliovirus Found in London 2022-06-22T04:00:00Z Once wild poliovirus has been eradicated from the planet, vaccination efforts may be able to switch to the inactivated polio vaccine, eliminating the risk of any future vaccine-derived cases. New York Polio Case Revives Questions About Live Oral Vaccine 2022-07-25T04:00:00Z The U.K. health security agency says it normally detects between one and three “poliovirus isolates per year” in sewage but they are normally one-offs and unrelated to each other. Traces of highly contagious poliovirus found in British sewage 2022-06-23T04:00:00Z Screening for poliovirus has been in place in many countries for decades, and several regions have kept tabs on illicit drugs in wastewater, but the pandemic has increased interest in looking for other diseases. Pandemic signals from the sewer—what virus levels in wastewater tell us 2022-03-08T05:00:00Z On 17 February, Malawi’s Ministry of Health announced a nasty surprise: A 3-year-old girl who was paralyzed in November 2021 was infected with the wild poliovirus, which Africa officially vanquished in 2020. Africa battles out-of-control polio outbreaks 2022-03-02T05:00:00Z In Britain, immunization for polio is carried out with an injected inactivated poliovirus, which cannot be shed through feces. Britain Declares National Incident After Poliovirus Found in London 2022-06-22T04:00:00Z The C.D.C. refers to polio as “a disabling and life-threatening disease caused by the poliovirus,” for instance, but fewer than five in a thousand people who contract the virus develop serious symptoms. The Strange Connection Between Mono and M.S. 2022-02-23T05:00:00Z In a setback for the global polio eradication campaign, a wild poliovirus has leapt from Pakistan to the African continent, where it has paralyzed a 3-year-old girl in Malawi. News at a glance: African vaccine factories, centipede-inspired robots, and Antarctic pollution 2022-02-23T05:00:00Z A wild poliovirus has made a leap from Pakistan to the African continent, where it has paralyzed a 3-year-old girl in Malawi—the first wild polio case in the country since 1992. In new setback for eradication campaign, poliovirus from Pakistan shows up in Africa 2022-02-16T05:00:00Z The new worries come as Pakistan and Afghanistan, the last two endemic countries, are doing surprisingly well, with just five reported cases of wild poliovirus last year, down from 140 in 2020. Africa battles out-of-control polio outbreaks 2022-03-02T05:00:00Z Wild poliovirus has been eliminated from every country in the world, except Afghanistan and Pakistan. Britain Declares National Incident After Poliovirus Found in London 2022-06-22T04:00:00Z The sick children did not have poliovirus, and health authorities ruled out other possible culprits, including West Nile virus, stroke and botulism. The Pandemic Set Off a Boom in Diagnostics 2022-02-16T05:00:00Z But the oral polio vaccine developed a few years later more successfully prevented infection by blocking the poliovirus from infiltrating through the gut. You got a coronavirus vaccine. But you still became infected. How did that happen? 2021-07-21T04:00:00Z Although Malawi is now considered a “wild-polio–affected country,” the African continent will still be considered free of wild poliovirus unless it circulates for 12 months or more. In new setback for eradication campaign, poliovirus from Pakistan shows up in Africa 2022-02-16T05:00:00Z Yet Pakistan has “exported” wild poliovirus before, sparking outbreaks that were quickly snuffed out, and the situation in Afghanistan and Pakistan improved dramatically last year, with polio cases tumbling to a historic low. Africa battles out-of-control polio outbreaks 2022-03-02T05:00:00Z In the dish, the poliovirus tried to attack the HeLa cells. Hidden Black Scientists Proved The Polio Vaccine Worked 2021-06-17T04:00:00Z In August, African countries were declared free of wild poliovirus, leaving Afghanistan and Pakistan as the only two countries where polio is endemic. A multibillion-dollar plan to end polio, and soon 2021-06-09T04:00:00Z But the poliovirus is a different type of virus than the novel coronavirus. COVID-19 vaccines — minus the needle? Researchers working on capsules, nasal sprays 2021-04-16T04:00:00Z But the last known case of wild polio on the continent occurred in 2016 in Borno state in Nigeria, and Africa was officially certified free of wild poliovirus in August 2021. In new setback for eradication campaign, poliovirus from Pakistan shows up in Africa 2022-02-16T05:00:00Z According to the United Nations, Afghanistan and neighboring Pakistan are the only two countries in the world where polio is still endemic, after Nigeria was last year declared free of the wild poliovirus. Afghan officials: 3 women working in polio drive killed 2021-03-30T04:00:00Z Pakistan and neighboring Afghanistan are the only two remaining countries in the world where polio is endemic, after Nigeria was last year declared free of the wild poliovirus. Pakistan launches anti-polio drive amid surge in coronavirus 2021-03-29T04:00:00Z Outbreaks of wild poliovirus — the original scourge — now occur only in Pakistan and Afghanistan. A multibillion-dollar plan to end polio, and soon 2021-06-09T04:00:00Z In 1960, Albert Sabin introduced a new polio vaccine, which contained a weakened form of poliovirus, rather than the completely inactivated virus in the Salk vaccine. To Beat COVID, We May Need a Good Shot in the Nose 2021-03-01T05:00:00Z Through sequence analysis of her poliovirus, the U.S. In new setback for eradication campaign, poliovirus from Pakistan shows up in Africa 2022-02-16T05:00:00Z Mainly because of the large-scale use of Sabin's vaccine, poliovirus has largely been eradicated from the planet. How a debate over two competing vaccines gripped the medical community — in 1961 2021-02-21T05:00:00Z The inactivated poliovirus vaccine developed by Jonas Salk did little to block infection or transmission of the virus, yet it powerfully prevented paralytic polio. How soon will COVID-19 vaccines return life to normal? 2021-02-16T05:00:00Z As the world adjusts to the idea of coexisting with the coronavirus for the foreseeable future, global health organizations are laying plans to eradicate another scourge that has already lingered for thousands of years: poliovirus. A multibillion-dollar plan to end polio, and soon 2021-06-09T04:00:00Z This made it more effective than the Salk vaccine in blocking poliovirus infection. To Beat COVID, We May Need a Good Shot in the Nose 2021-03-01T05:00:00Z Doctors proposed that a milder relative of the poliovirus must be at fault. What If You Never Get Better From Covid-19? 2021-01-21T05:00:00Z IgA antibodies induced by Sabin's vaccine prevented the poliovirus from attaching to and infecting intestinal cells. How a debate over two competing vaccines gripped the medical community — in 1961 2021-02-21T05:00:00Z Because the OPV uses a weakened live poliovirus, however, in rare cases among underimmunized populations, the attenuated virus mutates, circulates and once again causes illness. Vaccines Need Not Completely Stop COVID Transmission to Curb the Pandemic 2021-01-18T05:00:00Z The poliovirus mutates much more rapidly than the new coronavirus, yet polio vaccines remain highly effective. Will delaying second doses of COVID-19 vaccines spur viral resistance? 2021-01-13T05:00:00Z A microbiology lab that was long used to measure bacteria in wastewater, as well as viruses like the poliovirus and norovirus, was expanded to include the coronavirus analyses. What New York City’s Sewers Reveal About the Virus 2020-12-08T05:00:00Z Israel, however, was monitoring its wastewater for poliovirus. Watching What We Flush Could Help Keep a Pandemic Under Control 2020-11-24T05:00:00Z Sabin spent years weakening or attenuating the poliovirus by growing it repeatedly in different animals and in cells in the laboratory. How a debate over two competing vaccines gripped the medical community — in 1961 2021-02-21T05:00:00Z Now there are growing polio outbreaks; wild poliovirus transmission is increasing in the two remaining countries where it is endemic, Afghanistan and Pakistan. Opinion | The pandemic is triggering another disaster: Untreated diseases 2020-11-18T05:00:00Z Viral genomes, which are tiny, were produced first, starting in 2002 with the poliovirus's roughly 7,500 nucleotides, or code letters. Whole-Genome Synthesis Will Transform Cell Engineering 2020-11-13T05:00:00Z In the first half of the 1950s, with no cure and no vaccine, more than 200,000 Americans were disabled by the poliovirus. The Denialist Playbook 2020-11-08T05:00:00Z Despite the eradication of wild poliovirus, Africa’s fight against polio isn’t over. Africa declared free from wild polio — but vaccine-derived strains remain 2020-08-27T04:00:00Z Cases remain of the so-called vaccine-derived poliovirus, which is a rare mutated form of the weakened but live virus contained in the oral polio vaccine. Africa now free of wild poliovirus, but polio threat remains 2020-08-25T04:00:00Z “Until wild poliovirus is eradicated everywhere, it’s still a risk everywhere,” Michael Galway, a polio expert at the Bill and Melinda Gates Foundation, told Reuters, urging continued vigilance. Wild polio sufferers reflect as Africa set to be declared free of the disease 2020-08-25T04:00:00Z But sometimes patchy surveillance across the vast continent of 1.3 billion people raises the possibility that scattered cases of the wild poliovirus still remain, undetected. Africa now free of wild poliovirus, but polio threat remains 2020-08-25T04:00:00Z On Tuesday, Africa is to be declared free of the last remaining strain of wild poliovirus. Africa to be declared free of wild polio 2020-08-25T04:00:00Z But then, in 2016, four new cases of wild poliovirus were reported. Africa Celebrates the End of the Wild Poliovirus (but Not the End of All Polio) 2020-08-24T04:00:00Z The declaration leaves Pakistan and neighboring Afghanistan as the only countries thought to still have the wild poliovirus, with vaccination efforts against the highly infectious, water-borne disease complicated by insecurity and attacks on health workers. Africa now free of wild poliovirus, but polio threat remains 2020-08-25T04:00:00Z The 16 countries in Africa affected by circulating vaccine-derived poliovirus outbreaks include Angola, Burkina Faso, Cameroon, Ethiopia, Ghana, Nigeria and Zambia. Wild polio sufferers reflect as Africa set to be declared free of the disease 2020-08-25T04:00:00Z The final push to combat the wild poliovirus focused largely on northern Nigeria, where the Boko Haram Islamic extremist group has carried out a deadly insurgency for more than a decade. Africa now free of wild poliovirus, but polio threat remains 2020-08-25T04:00:00Z The poliovirus, for example, told us early on that a vaccine would be possible. Lessons for COVID-19 from the Early Days of AIDS 2020-07-06T04:00:00Z Circulating vaccine-derived poliovirus spreads in the same way, except that the virus mutates over time and causes polio. Africa Celebrates the End of the Wild Poliovirus (but Not the End of All Polio) 2020-08-24T04:00:00Z Africa's last reported case of the wild poliovirus was in Nigeria in 2016. Africa now free of wild poliovirus, but polio threat remains 2020-08-25T04:00:00Z But in 1955, an infamous accident – known as the Cutter incident--involving an inactivated poliovirus vaccine made by Jonas Salk harmed some children who received it. Operation Warp Speed’s opaque choices of COVID-19 vaccines draw Senate scrutiny 2020-07-03T04:00:00Z Africa’s last reported case of the wild poliovirus was in Nigeria in 2016. Africa now free of wild poliovirus, but polio threat remains 2020-08-25T04:00:00Z Billions of people have taken live poliovirus vaccine, nearly eradicating the disease. Decades-Old Soviet Studies Hint at Coronavirus Strategy 2020-06-24T04:00:00Z A mutated strain of poliovirus has been reported in more than 30 countries. Slowing the Coronavirus Is Speeding the Spread of Other Diseases 2020-06-14T04:00:00Z Similarly, in Mumbai, India, researchers were able to detect poliovirus in sewage three months before any cases were observed. Poop may tell us when the coronavirus lockdown will end 2020-04-29T04:00:00Z The country is one of 15 in Africa experiencing “vaccine-derived poliovirus outbreaks”, with cases spreading among parts of the populations yet to receive a vaccination. Polio campaign in Africa put on hold during coronavirus 2020-04-29T04:00:00Z “The poliovirus will inevitably continue to circulate and may paralyze more children as no high-quality immunization campaigns can be conducted in a timely manner,” said Pascal Mkanda, WHO’s coordinator of polio eradication in Africa. UN: New polio outbreak in Niger after vaccination suspended 2020-04-29T04:00:00Z When that vaccine was widely introduced in 1955, Dr. Albert Sabin was testing a vaccine using live but attenuated poliovirus, which could be taken orally. Decades-Old Soviet Studies Hint at Coronavirus Strategy 2020-06-24T04:00:00Z This is not trivial, as improved mucosal immunity is why the Sabin polio vaccine prevents transmission of poliovirus, whereas the Salk vaccine does not. Beware of Antibody-based COVID-19 "Immunity Passports" 2020-04-28T04:00:00Z The monitoring program, set up in 1989 by the Israeli health department, had previously detected at least four other “silent” episodes of poliovirus before clinical cases were reported. Poop may tell us when the coronavirus lockdown will end 2020-04-29T04:00:00Z In Israel, for example, officials found the poliovirus in the sewage system in 2013 and mounted a vaccination campaign in response. Sewer systems are a window into the coronavirus pandemic 2020-04-20T04:00:00Z The novel oral polio vaccine is more genetically stable — and hopefully less prone to sparking vaccine-derived poliovirus outbreaks — than the current version. Around the world, a new disease stalls efforts to fight old ones 2020-04-18T04:00:00Z The agency raised safety concerns, including the chance of live poliovirus making its way into water supplies and infecting others, according to researchers familiar with the study application. Decades-Old Soviet Studies Hint at Coronavirus Strategy 2020-06-24T04:00:00Z On top of that, polio fighters were struggling with outbreaks of a form of the poliovirus that can emerge in under-immunized populations. Opinion | Prepare for collateral damage as devastating as the virus 2020-04-16T04:00:00Z In 1952, the iron lung was the main way to treat the paralysis that stopped some people with poliovirus from breathing. The outbreak that invented intensive care 2020-04-02T04:00:00Z In the subsequent chain of infection from person to person, the virus may mutate in the human body into more virulent and transmissible forms—and begin to circulate like a wild poliovirus among unvaccinated children. Two Strains of Polio Down, One to Go 2019-10-23T04:00:00Z Given the similarities between polio and AFM, researchers looked to see if the poliovirus was the culprit. Why we don't know more about rare polio-like illness 2019-08-10T04:00:00Z Into each waiting mouth, a parent popped a sugar cube laced with weakened poliovirus — an early vaccine against a dreaded disease. Decades-Old Soviet Studies Hint at Coronavirus Strategy 2020-06-24T04:00:00Z If you wanted a petri-dish for poliovirus, you couldn’t do much better than eastern Kansas. Measles cases flare beyond 700 and anti-vaxxers — the apex helicopter parent — are to blame 2019-05-01T04:00:00Z Environmental surveillance earlier this year detected poliovirus in the sewage of 10 cities in the country. Killings of police and polio workers halt vaccine drive in Pakistan 2019-04-30T04:00:00Z The most alarming of them is the emergence and spread of vaccine-derived type 2 poliovirus, mainly in Africa. Two Strains of Polio Down, One to Go 2019-10-23T04:00:00Z He found the rules of the geometrical form of poliovirus and other spherical viruses. Aaron Klug (1926-2018) 2018-12-11T05:00:00Z But the same is true for the poliovirus, which causes only mild symptoms, or none at all, in more than 99% of those infected. U.S. reports new cases of puzzling, poliolike disease that strikes children 2018-10-16T04:00:00Z An inactivated form of the poliovirus used to treat recurrent brain tumors is showing what researchers called encouraging long-term survival in a Phase 1 clinical trial published Tuesday. Poliovirus Therapy Shows Early Promise for Treating Aggressive Brain Cancer, But Questions Linger 2018-06-27T04:00:00Z Survival was better than expected for patients in a small study who were given genetically modified poliovirus, which helped their bodies attack the cancer, doctors report. Enemy turned ally: Poliovirus is used to fight brain tumors 2018-06-26T04:00:00Z Success there, says Carol Pandak of Rotary International, means the entire African continent could be certified free of all three strains of wild poliovirus sometime next year. Two Strains of Polio Down, One to Go 2019-10-23T04:00:00Z More than 20 years ago, Eckard Wimmer, a geneticist at Stony Brook University in New York, highlighted the potential dangers of synthetic biology in dramatic style when he recreated poliovirus in a test tube. Urgent need to prepare for manmade virus attacks, says US government report 2018-06-19T04:00:00Z Just last year, poliovirus seemed on its last legs in Pakistan, one of its final strongholds. Top Stories: Polio’s Pakistani stronghold, salad-eating sharks, and the killer inside you 2018-01-12T05:00:00Z In the study, 61 patients with recurrent glioblastoma were treated with a poliovirus vaccine modified to preferentially target a protein found on brain tumor cells and set off an immune response. Poliovirus Therapy Shows Early Promise for Treating Aggressive Brain Cancer, But Questions Linger 2018-06-27T04:00:00Z With the help of the National Cancer Institute, they genetically modified poliovirus so it would not harm nerves but still infect tumor cells. Enemy turned ally: Poliovirus is used to fight brain tumors 2018-06-26T04:00:00Z The international effort to achieve this goal passed a major milestone this week with the worldwide eradication of wild poliovirus type 3. Two Strains of Polio Down, One to Go 2019-10-23T04:00:00Z Just a year ago, poliovirus seemed on its last legs in Pakistan, one of its final strongholds. "What the hell is going on?" Polio cases are vanishing in Pakistan, yet the virus won't go away 2018-01-11T05:00:00Z “In the past days, yet another case of wild poliovirus was found,” Mr. Lanzer said. In Polio’s Worst-Hit District, Vaccinators Strain for Access 2017-12-19T05:00:00Z The difference in median survival of slightly more than one month favored the poliovirus therapy over the historical control, but it was not statistically significant. Poliovirus Therapy Shows Early Promise for Treating Aggressive Brain Cancer, But Questions Linger 2018-06-27T04:00:00Z After two years, the poliovirus group started faring better. Enemy turned ally: Poliovirus is used to fight brain tumors 2018-06-26T04:00:00Z The announcement, due Thursday from the Global Commission for the Certification of the Eradication of Poliomyelitis comes just four years after eradication of wild poliovirus type 2. Two Strains of Polio Down, One to Go 2019-10-23T04:00:00Z The starting material was the genetic code for making the outer surface of poliovirus. Plants 'hijacked' to make polio vaccine - BBC News 2017-08-15T04:00:00Z And though simply putting the poliovirus genome into a suitable cell will lead to the production of new virus particles, that trick does not work for poxviruses. How Canadian researchers built a poxvirus for $100,000 using mail-order DNA 2017-07-06T04:00:00Z At one year, 54 percent of the poliovirus patients were alive compared to 45 percent of the historical control patients. Poliovirus Therapy Shows Early Promise for Treating Aggressive Brain Cancer, But Questions Linger 2018-06-27T04:00:00Z The Global Polio Eradication Initiative routinely sequences all poliovirus isolates collected from people diagnosed with the disease. Four steps to precision public health 2016-12-04T05:00:00Z It leaves only a single strain, wild poliovirus type 1, on the loose. Two Strains of Polio Down, One to Go 2019-10-23T04:00:00Z The virus-like particles prevented polio in animal experiments, and an analysis of their 3D structure showed they looked almost identical to poliovirus. Plants 'hijacked' to make polio vaccine - BBC News 2017-08-15T04:00:00Z Researchers had assumed it would one day be possible to synthesize poxviruses since virologists assembled the much smaller poliovirus from scratch in 2002. How Canadian researchers built a poxvirus for $100,000 using mail-order DNA 2017-07-06T04:00:00Z After 18 months, the Duke researchers say a small group of poliovirus patients began to show signs of extended survival. Poliovirus Therapy Shows Early Promise for Treating Aggressive Brain Cancer, But Questions Linger 2018-06-27T04:00:00Z Those include cases from wild poliovirus as well as a vaccine-derived form. Billionaires Pony Up More Funds in Fight to Eradicate Polio 2016-10-24T04:00:00Z It would mean seeing the world’s last cases of wild poliovirus sometime next year—down from 88 cases so far in 2019—followed by a minimum of three years of intensive monitoring to certify eradication. Two Strains of Polio Down, One to Go 2019-10-23T04:00:00Z And using weakened poliovirus in current vaccines poses a risk of the virus regaining some of its dangerous traits - called vaccine-derived poliovirus. Plants 'hijacked' to make polio vaccine - BBC News 2017-08-15T04:00:00Z But the new work—like the poliovirus reconstitutions before it—is raising troubling questions about how terrorists or rogue states could use modern biotechnology. How Canadian researchers built a poxvirus for $100,000 using mail-order DNA 2017-07-06T04:00:00Z At two years of follow-up, 21 percent of the poliovirus patients remained alive compared to 14 percent of the control patients. Poliovirus Therapy Shows Early Promise for Treating Aggressive Brain Cancer, But Questions Linger 2018-06-27T04:00:00Z Though a cousin of poliovirus, it was only supposed to cause a runny nose and cough. Hundreds of American kids are suddenly paralyzed, and doctors still don’t know why 2016-10-21T04:00:00Z As the last two countries reporting wild poliovirus, Pakistan and Afghanistan are now feeling “tremendous global pressure to get the job done,” Pandak says. Two Strains of Polio Down, One to Go 2019-10-23T04:00:00Z The vaccine is an "authentic mimic" of poliovirus called a virus-like particle. Plants 'hijacked' to make polio vaccine - BBC News 2017-08-15T04:00:00Z Genetic sequencing suggests these isolates are most closely linked to the wild poliovirus type 1 that was last detected in the state in 2011. New Outbreak Threatens Nigeria's Efforts to Eradicate Polio 2016-08-15T04:00:00Z At three years, the survival gap widened further, with 21 percent of the poliovirus patients still alive compared to just 4 percent of the controls. Poliovirus Therapy Shows Early Promise for Treating Aggressive Brain Cancer, But Questions Linger 2018-06-27T04:00:00Z Then she decided to check for other viruses in the same family as poliovirus, known as enterovirus. Hundreds of American kids are suddenly paralyzed, and doctors still don’t know why 2016-10-21T04:00:00Z Improving surveillance for poliovirus cases — for instance, in healthy individuals and in the environment — is another priority, Rosenbauer says. Polio eradication faces setback as Nigeria records first cases in two years 2016-08-11T04:00:00Z Outwardly it looks almost identical to poliovirus but - like the difference between a mannequin and person - it is empty on the inside. Plants 'hijacked' to make polio vaccine - BBC News 2017-08-15T04:00:00Z The poliovirus can infect the brain and spinal cord, and while most people who get it don’t have any symptoms, about one in 200 are paralyzed temporarily or permanently, according to the U.S. Century after 1st major US polio epidemic, eradication eyed 2016-06-25T04:00:00Z At two years, only eight of the 61 poliovirus patients were still alive and accounted for in the survival analysis. Poliovirus Therapy Shows Early Promise for Treating Aggressive Brain Cancer, But Questions Linger 2018-06-27T04:00:00Z Landsteiner also collaborated with scientist Erwin Popper to lay the foundation that led to the discovery of the poliovirus, thus enabling the treatment of a disease that afflicted millions of children. New Google Doodle Honors Biologist Karl Landsteiner 2016-06-14T04:00:00Z Some of these RNA viruses, such as H.I.V. and poliovirus, attack our species. Scientists Find Form of Crispr Gene Editing With New Capabilities 2016-06-03T04:00:00Z Children were imbibing less human waste, and encountering the poliovirus later and later. Educate Your Immune System 2016-06-03T04:00:00Z What health officials didn’t realize, Wilson said, was that only a fraction of the people who were infected with the poliovirus had symptoms of paralysis. Century after 1st major US polio epidemic, eradication eyed 2016-06-25T04:00:00Z “When you look into the details of the poliovirus survival analysis, a one-month median survival compared to Duke’s historical control doesn’t look that great,” said Lassman. Poliovirus Therapy Shows Early Promise for Treating Aggressive Brain Cancer, But Questions Linger 2018-06-27T04:00:00Z Outbreaks of “vaccine-derived poliovirus” can usually be contained in a few months. Progress in Jimmy Carter’s Quest to End Guinea Worm Disease 2016-01-11T05:00:00Z At one point, he began to speculate about how the altered poliovirus worked, before catching himself. Bacteria on the Brain 2015-12-07T05:00:00Z One popular theory holds that if the poliovirus arrives in infancy, it produces mild if any symptoms. Educate Your Immune System 2016-06-03T04:00:00Z Fear gripped the country each summer in the early part of the 20th century, when thousands of children caught the poliovirus before two types of vaccines were developed in the 1950s. Century after 1st major US polio epidemic, eradication eyed 2016-06-25T04:00:00Z The next clinical trial of the poliovirus therapy is not likely to settle this important survival question. Poliovirus Therapy Shows Early Promise for Treating Aggressive Brain Cancer, But Questions Linger 2018-06-27T04:00:00Z Researchers at the Mayo Clinic and Duke University have been using genetically engineered versions of the measles virus and poliovirus to treat multiple myeloma and brain cancer, respectively. Immunotherapy’s Promise Against Cancer 2015-10-06T04:00:00Z Studies he did at the time suggested that poliovirus has a strong affinity for brain cancer: receptors that the virus targets are prevalent on the surface of tumors. Bacteria on the Brain 2015-12-07T05:00:00Z And the last recorded case of wild poliovirus in all of Africa occurred in August 2014 in Somalia. Nigeria Declared Polio-Free by WHO 2015-09-25T04:00:00Z Late last month , Nigeria passed a full year without a case of wild poliovirus. The end of polio in Africa? 2015-08-20T04:00:00Z One group will receive the poliovirus therapy and chemotherapy; the other group will receive poliovirus alone. Poliovirus Therapy Shows Early Promise for Treating Aggressive Brain Cancer, But Questions Linger 2018-06-27T04:00:00Z The poliovirus entered the body through the mouth and multiplied in the gastrointestinal tract. Vaccinations Have Always Been Controversial in America 2015-07-31T04:00:00Z Gromeier created the altered poliovirus twenty-one years ago, when he was a postdoctoral fellow. Bacteria on the Brain 2015-12-07T05:00:00Z As a result, Nigeria hasn’t recorded a case of polio caused by wild poliovirus since July 2014, according to the WHO. Nigeria Declared Polio-Free by WHO 2015-09-25T04:00:00Z Quickly, the poliovirus did what all viruses do when they’re given that kind of running room: it spread, and fast. This Is How Nigeria Beat Polio 2015-07-24T04:00:00Z Bolognesi, a co-author of the Phase 1 study, said the company is working with the Food and Drug Administration to plan additional studies that might compare poliovirus therapy against a standard of care. Poliovirus Therapy Shows Early Promise for Treating Aggressive Brain Cancer, But Questions Linger 2018-06-27T04:00:00Z Second, there are no known animal reservoirs of the poliovirus. Polio Nearly Eradicated in Nigeria, Pushing Disease to Brink of Extinction 2015-07-24T04:00:00Z The US Public Health Service soon replaced Salk’s killed-virus vaccine, given by injection, with Albert Sabin’s oral vaccine, made of live, weakened poliovirus, delivered in a sugar cube, citing cost and convenience. 5 Things You May Not Know About Jonas Salk 2015-06-22T04:00:00Z That is significant because poliovirus also enters the bloodstream before invading the central nervous system. Enterovirus 68 May Be Linked to Paralysis in Children, Study Says 2015-03-30T04:00:00Z An engineered version of the poliovirus has been in development for more than 20 years as a treatment for one of the most difficult-to-treat cancers, a brain tumor called glioblastoma multiforme, abbreviated GBM. 60 Minutes Covers Duke's Polio Virus Clinical Trial Against Glioblastoma 2015-03-30T04:00:00Z It belongs to the enterovirus family, which includes poliovirus and the pathogens that cause common colds; it is most similar to the rhinoviruses that cause respiratory infections. Mystery childhood paralysis stumps researchers 2015-01-27T05:00:00Z “Interrupting all poliovirus circulation in Nigeria is achievable,” the report finds, but only with expanded vaccination coverage to some of the region’s most remote and hard-to-reach communities. Africa Nears Polio Eradication, CDC Says 2014-11-20T05:00:00Z The last case of type 3 poliovirus was detected in Pakistan in November 2012, according to the CDC report. 'Major milestone' in polio battle 2014-11-14T05:00:00Z The viruses were genetically very similar, the scientists found, sharing certain mutations that resemble those found in the poliovirus genome. Enterovirus 68 May Be Linked to Paralysis in Children, Study Says 2015-03-30T04:00:00Z Unlike the spiky sea urchin that is influenza, or the golf-ball shaped poliovirus, Ebola resembles noosed ropes under the electron microscopes used to capture viral images. How Ebola Blindsides the Body's Defenses 2014-11-07T05:00:00Z But some types—including poliovirus, which causes paralysis—are dangerous. Is An Unusual Virus Spreading in the Midwest? 2014-09-11T04:00:00Z When the committee of imams was launched in 2009, there were 384 new wild poliovirus cases reported in Nigeria, most in the northern states. Muslim clerics in Nigeria advocate for polio vaccination and mobilize community As long as any wild poliovirus is out there, everyone needs to be protected. Total War on Polio: The Battle in Pakistan 0002-11-29T05:00:00Z The spread of wild poliovirus is a public-health emergency that requires a coordinated global response, the World Health Organization declared on 5 May. Seven days: 2–8 May 2014 2014-05-07T17:20:15.324Z It says Pakistan, Cameroon, and Syria "pose the greatest risk of further wild poliovirus exportations in 2014." World facing polio health emergency 2014-05-05T17:23:50Z While the wild poliovirus continues to circulate, mass immunisations must continue in every country in the world. Why is polio a public emergency? 2014-05-06T15:14:32Z History notes that when he grew up, he had a little score-settling to do with the poliovirus. Dear Anti-Vaxxers: You Want Pure Nature? OK, Die Young. 2014-04-02T16:59:18Z Because the fit must be precise, poliovirus typically unlocks only the cells responsible for controlling muscles in the arms and legs — the motor neurons — in the front part of the spinal cord. How virus sleuths and public health officials track the cause of a mysterious illness 2014-03-10T15:47:44Z A polio outbreak also began in war-torn Syria, and wild poliovirus persisted in southern Israel, leading to mass vaccinations across the Middle East to try to . 365 days: 2013 in review 2013-12-18T18:50:23.347Z “Hamid led the program in India that stopped the spread of poliovirus.” CDC doctor led polio eradication project in India 2013-12-17T14:55:58Z The current poliovirus outbreaks are sad reminders that infectious diseases are one of the few true beneficiaries of war. Infections: War's true beneficiaries 2013-12-07T01:02:06Z For example, Aaron Ernst produced a piece on an attenuated poliovirus in clinical trials at Duke Cancer Institute to target the brain cancer, malignant glioma. The Return Of TV Science And Medical Journalism At Al Jazeera America 2013-08-22T12:36:00Z Since polio has been eradicated in the United States and the patients in California were vaccinated against it, the suspicion has fallen on other members of the enterovirus family, to which poliovirus belongs. How virus sleuths and public health officials track the cause of a mysterious illness 2014-03-10T15:47:44Z Numbers of cases of polio are falling in Nigeria, Pakistan and Afghanistan, countries where wild poliovirus is endemic. Seven days: 16–22 August 2013 2013-08-21T17:50:13.697Z If a vaccinated patient made antibodies that would prevent the disease, then their blood plasma would prevent polio infection when mixed with HeLa cells and poliovirus in the lab. Ethical Justice, But No Financial Rewards, For The Henrietta Lacks Family 2013-08-08T17:29:00Z Similarly in Africa, political obstruction to vaccination campaigns means that poliovirus continues to circulate in northern Nigeria and and the wider Horn of Africa. Infections: War's true beneficiaries 2013-12-07T01:02:06Z The few scattered areas where naturally occurring poliovirus still cripples young people tend to be, practically by definition, some of the poorest, most chaotic environments imaginable. Epidemiological Endgame: Is Polio on the Brink of Eradication? 2013-04-18T13:15:00.360Z Two of the victims in California had Enterovirus 68, another relative of poliovirus, in their nasal secretions. How virus sleuths and public health officials track the cause of a mysterious illness 2014-03-10T15:47:44Z But outbreaks have occurred in Somalia and Kenya, part of a band of African countries in which imported poliovirus tends to cause periodic reinfections. Seven days: 16–22 August 2013 2013-08-21T17:50:13.697Z Health officials in Egypt and the world are scrambling to prevent an outbreak of polio after poliovirus from Pakistan was discovered in sewage samples collected at two sites in Cairo in December. Polio Virus Spreads from Pakistan to Egypt 2013-01-24T17:30:00Z Karachi - where four female health workers were shot yesterday is one of a number of areas in Pakistan where wild poliovirus is being spread. Polio killings a major setback 2012-12-19T12:55:13Z The injectable vaccine used in Britain and other developed countries contains an inactivated, or killed poliovirus. Vaccine checks 'to control polio' 2012-11-26T11:22:15Z One, at Duke University in Durham, North Carolina, injects patients’ brains with weakened, engineered poliovirus. Can Bacteria Fight Brain Cancer 2012-07-30T16:15:00.220Z This idea began to change in 2002, when the poliovirus was synthesized de novo. Preventing pandemics: The fight over flu 2012-01-18T18:20:33.007Z Still, the program fell short of meeting its goal of stopping poliovirus transmission in two endemic countries by the end of 2011. India Marks 1 Year Without Polio, But Global Eradication Remains Uncertain 2012-01-12T21:21:57Z And on Thursday, the World Health Organization reported an outbreak of wild poliovirus type 3, with three new cases reported in January and February and accompanied by the onset of paralysis. Disease claims young victims in Ivory Coast crisis 2011-04-22T18:31:05Z "The main advantage of the bivalent is that it is so effective against type 1 and type 3 poliovirus at the same time," Sutter told Reuters in a telephone interview. Double polio vaccine holds promise for ending virus 2010-10-26T14:05:00Z "The main advantage of the bivalent is that it is so effective against type 1 and type 3 poliovirus at the same time," he told Reuters in a telephone interview. Double polio vaccine proves most effective in study 2010-10-25T23:03:00Z The first to be made, eight years ago, was poliovirus. Baby Steps to New Life-Forms 2010-05-28T01:23:00Z “Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template.” Baby Steps to New Life-Forms 2010-05-28T01:23:00Z |
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