| 单词 | phenylalanine |
| 例句 | These metabolites include phenylalanine, aspartic acid and methanol. Does aspartame cause cancer? "Possibly," a new WHO report concludes 2023-07-14T04:00:00Z The WHO reports show that aspartame itself is rapidly broken down in the gut into three other substances - phenylalanine, aspartic acid and methanol. Aspartame advice unchanged despite cancer question 2023-07-13T04:00:00Z Untreated, this can lead to an accumulation of phenylalanine, which can lead to intellectual disabilities. Chemistry 2019-02-14T00:00:00Z Figure 15.15 This is a space-filling model of a tRNA molecule that adds the amino acid phenylalanine to a growing polypeptide chain. Biology for AP Courses 2022-06-09T00:00:00Z People afflicted with PKU lack sufficient activity of the enzyme phenylalanine hydroxylase and are therefore unable to break down phenylalanine into tyrosine adequately. Anatomy and Physiology 2013-06-19T00:00:00Z However, for individuals with a rare genetic disorder called phenylketonuria, phenylalanine can accumulate and cause health issues, so they are sometimes instructed to avoid it. Does aspartame cause cancer? "Possibly," a new WHO report concludes 2023-07-14T04:00:00Z These are people with an inherited disease called phenylketonuria or PKU, who are born unable to metabolise the phenylalanine that is released as aspartame is broken down. Aspartame advice unchanged despite cancer question 2023-07-13T04:00:00Z In the disease phenylketonuria, a defect in the shape of phenylalanine hydroxylase causes it to lose its function in breaking down phenylalanine. Chemistry 2019-02-14T00:00:00Z The amino acid phenylalanine is attached to the other end of the tRNA. Biology for AP Courses 2022-06-09T00:00:00Z Because of this, levels of phenylalanine rise to toxic levels in the body, which results in damage to the central nervous system and brain. Anatomy and Physiology 2013-06-19T00:00:00Z With this knowledge, the family started their child on treatment with a specialized diet including low levels of phenylalanine. How Big Data Are Unlocking the Mysteries of Autism 2021-04-30T04:00:00Z People with PKU aren’t able to properly process phenylalanine, making aspartame highly toxic. Mom claims diet soda sent her into a coma after severe allergic reaction 2019-10-08T04:00:00Z Kuvan reduces the levels of phenylalanine in many people who have PKU. Make 'life-changing' drug affordable - MPs 2019-05-10T04:00:00Z This molecule disrupts the synthesis of phenylalanine, tyrosine, and tryptophan. Biology for AP Courses 2022-06-09T00:00:00Z The person must closely follow a strict diet that is low in phenylalanine to avoid symptoms and damage. Anatomy and Physiology 2013-06-19T00:00:00Z A second gene encodes an enzyme that breaks down the phenylalanine into fragments. Scientists Are Retooling Bacteria to Cure Disease 2018-09-04T04:00:00Z Also notable is Saotome and colleagues’ finding that a phenylalanine residue at a pore constriction affects both permeation and the rate at which the channel is inactivated when subjected to a prolonged stimulus. Force-activated ion channels in close-up 2018-02-11T05:00:00Z "S" has phenylketonuria or PKU, and his parents wanted him to take a drug called Kuvan to help him metabolise phenylalanine, an amino acid found in some proteins, which would cost about £100 a day. NHS agrees to fund boy's £100-a-day drug 2017-09-29T04:00:00Z For phenylketonuria, the company inserted an enzyme — also switched on under anaerobic conditions — that helps to break down the amino acid phenylalanine, which patients cannot otherwise metabolize. Therapeutic developments: Masters of medicine : Nature : Nature Research 2017-05-16T04:00:00Z Pregnant women with PKU are at a high risk for exposing the fetus to too much phenylalanine, which can cross the placenta and affect fetal development. Anatomy and Physiology 2013-06-19T00:00:00Z The Synlogic team wanted the microbes to break down phenylalanine only in the right place and at the right time in the human body. Scientists Are Retooling Bacteria to Cure Disease 2018-09-04T04:00:00Z It is true that people with phenylketonuria, a rare genetic disorder, need to limit their consumption of aspartame, since phenylalanine is one of its components. The Evidence Supports Artificial Sweeteners Over Sugar 2015-07-27T04:00:00Z In one patient a hepatocyte transplant reduced her phenylalanine level by almost half. With Liver Donors in Short Supply, Cell Transplants Offer New Options 2015-02-17T05:00:00Z It has since shown that the bacteria can blunt the increase of ammonia and phenylalanine levels in mouse models. Therapeutic developments: Masters of medicine : Nature : Nature Research 2017-05-16T04:00:00Z Some animal products and certain starches are also high in phenylalanine, and intake of these foods should be carefully monitored. Anatomy and Physiology 2013-06-19T00:00:00Z So they engineered the bacteria to keep their phenylalanine genes shut down if they sensed high levels of oxygen around them. Scientists Are Retooling Bacteria to Cure Disease 2018-09-04T04:00:00Z Like aspartame, advantame contains phenylalanine, which is metabolized with difficulty by people with a rare genetic disorder, phenylketonuria. New artificial sweetener wins FDA approval 2014-05-21T04:00:00Z That condition leaves the body unable to break down phenylalanine, an amino acid present in many foods. With Liver Donors in Short Supply, Cell Transplants Offer New Options 2015-02-17T05:00:00Z In addition to caffeine, the product also combines high levels of Niacin, Vitamin B6 and Vitamin B12 and a slew of other products meant to increase energy including citicoline, phenylalanine and taurine. Energy drinks come under scrutiny: do you use them to stay awake? 2012-11-15T20:30:00Z But only phenylalanine levels in a mother's first trimester were related to the risk of facial deformities. Stick with PKU therapy before pregnancy: study 2012-01-10T19:23:19Z When monkeys without the microbes ate a high-protein diet, they experienced a spike of phenylalanine in their blood. Scientists Are Retooling Bacteria to Cure Disease 2018-09-04T04:00:00Z Tryptophan is also included for comparison because it is physicochemically similar to phenylalanine and tyrosine. [Technical Response] Response to Comment on ?Positive Selection of Tyrosine Loss in Metazoan Evolution? 2011-05-19T18:25:18.573Z Because the genetic code was known to consist of triplets, the experiment showed that UUU is the codon for phenylalanine, U being the symbol for uracil. 2010-01-21T07:10:00Z Thus, constrained substitution of phenylalanine and tryptophan with tyrosine is possibly another mechanism contributing to OTD and supports our observation that there is selection pressure to remove tyrosines for signaling fidelity. [Technical Response] Response to Comment on ?Positive Selection of Tyrosine Loss in Metazoan Evolution? 2011-05-19T18:25:18.573Z We observed that the substitution rate of phenylalanine by tyrosine from yeast to human for pTyr proteins is similar to the rate for human to yeast. [Technical Response] Response to Comment on ?Positive Selection of Tyrosine Loss in Metazoan Evolution? 2011-05-19T18:25:18.573Z In addition, the more bacteria they ingested, the more bits of phenylalanine wound up in their urine — a sign the bacteria were doing their job. Scientists Are Retooling Bacteria to Cure Disease 2018-09-04T04:00:00Z This phenomenon is minimally influenced by GC force because only T ↔ A substitution is required to directly switch between phenylalanine and tyrosine. [Technical Response] Response to Comment on ?Positive Selection of Tyrosine Loss in Metazoan Evolution? 2011-05-19T18:25:18.573Z We then computed the frequency of mutated phenylalanine and tryptophan being substituted with tyrosine from yeast to human and vice versa. [Technical Response] Response to Comment on ?Positive Selection of Tyrosine Loss in Metazoan Evolution? 2011-05-19T18:25:18.573Z |
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