| 单词 | oestrogen |
| 例句 | Hormonal treatments that slow down or stop the production of oestrogen are therefore commonly used to treat it. Endometriosis: 20 things every woman (and every doctor) should know 2015-09-27T04:00:00Z The condition arises when the hypothalamus prompts the pituitary gland to release a cocktail of dopamine, norepinephrine, phenylethylamine, oestrogen and testosterone. Michael Haneke's Amour gives love an unsettling closeup 2012-11-19T15:08:28Z When oestrogen is lacking, a woman does not experience the same level of lubrication as a preparation for sex. Is testosterone really the answer to my post-menopausal sexual problems? 2019-10-29T04:00:00Z But research suggests pill-taking women – in their state of artificial progesterone dominance and lacking a cyclical oestrogen urge – seem to prefer the faces of men who are less masculine. Dr Sarah E Hill: ‘We have a blind spot about how the pill influences women’s brains’ 2019-10-19T04:00:00Z Mixing alcohol with oestrogen, women are frequently told, is a recipe for disaster. 'Go smoke free. Stay pretty’ – the health campaigns that haven’t heard of feminism 2016-09-08T04:00:00Z They say that HRT “is a highly successful treatment for common symptoms of menopause”, and that HRT with oestrogen alone “is associated with little or no change in the risk of breast cancer”. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z “While the risk versus benefits profile for oestrogen alone is positive for younger women, it’s important to note that these data only pertain to the short-term use of hormone therapy,” he said. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z Oestrogen is involved in a range of bodily functions, and oestrogen receptors are found in cells throughout the body: the brain, the breasts, the bones, the belly. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z Most breast cancers are hormone sensitive, meaning they are fuelled by the female hormone oestrogen. Breast cancer could be 'stopped in its tracks' by new technique, say scientists 2015-05-27T04:00:00Z I understand that oestrogen – or a lack of it – is to blame. 'I miss what I used to be like': women's stories of the menopause 2019-08-25T04:00:00Z Ageing, and menopause in particular, causes a woman’s oestrogen levels to decline. 10 things you need to know about vaginas 2016-09-24T04:00:00Z They intended to do this by smuggling oestrogen into his food, thereby turning him into a woman. Breaking the cycle: women are learning to love their hormones 2018-02-25T05:00:00Z Of these, 16,608 women who had an intact uterus were in the study of oestrogen plus progestin and 10,739 without a uterus participated in the trial of oestrogen alone. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z This week, there's some welcome oestrogen, with trucker Lisa looking to redeem herself after she dumped her last load in a ditch. TV highlights 22/03/2013 2013-03-22T07:00:07Z The menopause is a natural part of ageing and usually occurs between 45 and 55 years of age after levels of the hormone oestrogen have declined to the point where ovulation and menstruation stop. 'I miss what I used to be like': women's stories of the menopause 2019-08-25T04:00:00Z Testosterone tends to diminish, while oestrogen and prolactin rise. ‘My oestrogen levels were all over the place’: when men have ‘sympathy pregnancies’ 2019-07-22T04:00:00Z They are not, but they are suffering from the wide-ranging power of oestrogen in the body. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z There is hard evidence of the protective effect of oestrogen for adverse cardiac events. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z A statement attributed to the then acting director of the WHI, Jacques Rossouw, said that “the adverse effects of oestrogen plus progestin applied to all women, irrespective of age, ethnicity, or prior disease status”. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z The oestrogen is to replace the body’s falling levels and the progestogens to protect the endometrium: though the mechanism is unclear, adding oestrogen without a progestational agent increases the risk of endometrial cancer. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z He escaped prison only by agreeing to chemical castration through a year's doses of oestrogen – which curator David Rooney said had a devastating effect on him, mentally and physically. Alan Turing: the short, brilliant life and tragic death of an enigma 2012-06-20T16:48:51Z All in all, The Dark Knight Rises appears to have been given a serious oestrogen injection. The Dark Knight Rises trailers show Batman has had an oestrogen injection 2012-05-25T15:02:27Z I was given a course of injections of leuprorelin, a drug that blocks the production of oestrogen. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z Every month, she releases one, a process triggered by the release of hormones, including oestrogen. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z One is called testosterone, one is called oestrogen. Antony Hegarty: 'We need more oestrogen-based thinking' 2012-05-19T23:04:35Z As women age, we produce less of the important hormones that are present earlier in life – notably oestrogen and testosterone – that enhance sex and make it comfortable. Is testosterone really the answer to my post-menopausal sexual problems? 2019-10-29T04:00:00Z Some, though, were hopeful of a new combined HRT drug that contains equine oestrogen and bazedoxifene, a selective oestrogen receptor modulator, that can modulate any damaging effects of oestrogen on uterus and breast tissue. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z Every woman’s body reacts differently to changes in oestrogen levels, making a certain diagnosis of the menopause difficult. What science doesn’t know about the menopause: what it’s for and how to treat it | Rose George 2015-12-15T05:00:00Z This has been largely discredited because the female menopause happens when a woman’s body suddenly produces far less oestrogen; more like a cliff-edge. ‘My energy is back’: how testosterone replacement therapy is changing men’s lives 2019-09-09T04:00:00Z For example, women who have had a hysterectomy, and so do not have a womb, will not need to take "protective" progesterone alongside oestrogen in their HRT because they cannot get womb cancer. NHS talking therapy recommended for menopause symptoms 2023-11-16T05:00:00Z That includes oestrogen gel which had been in short supply. HRT: Sharp rise in prescriptions after menopause campaign 2023-10-27T04:00:00Z And almost 20% of the women who carry FVL, were prescribed oestrogen and had two medical conditions suffered a blood clot. Women given new insight into blood clot risk 2023-09-19T04:00:00Z It can affect levels of oestrogen and losing your period can be a warning sign of the condition. Team GB rower 'alienated' after return from pregnancy 2023-06-15T04:00:00Z As oestrogen levels become unstable, people can experience a range of symptoms such as hot flushes, night sweats, anxiety and joint pain. Utrogestan: Menopause pill supply restricted over shortages 2023-05-20T04:00:00Z For 1,000 on combined oestrogen and progesterone HRT there might be one extra case. NHS talking therapy recommended for menopause symptoms 2023-11-16T05:00:00Z The condition affects both men and women, and can impact levels of oestrogen - an essential hormone for bone health. The 'damaging' idea that 'thinner is faster' 2023-03-08T05:00:00Z The presence of the FVL gene made a substantial difference to risk, with only around 5% of women taking oestrogen and having two conditions suffering a clotting event. Women given new insight into blood clot risk 2023-09-19T04:00:00Z Increased presence of fat tissue can elevate levels of the hormone oestrogen, which has been linked to the cancer. US cancer death rate drops by 30% since 1991 2023-01-12T05:00:00Z During the menstrual cycle when oestrogen is elevated, which usually happens in the second week, it can affect the stability of joints, making them looser and more lax. Why do so many women footballers get ACL injuries? 2022-12-21T05:00:00Z Combined HRT does not increase the risk of stroke when the oestrogen component is taken as a skin patch or gel, but does slightly increase the risk if taken as a tablet, says NICE. NHS talking therapy recommended for menopause symptoms 2023-11-16T05:00:00Z The impact on oestrogen means losing your period can be a warning sign of Red-S. The 'damaging' idea that 'thinner is faster' 2023-03-08T05:00:00Z While oestrogen use, FVL, and common medical conditions are all known risk factors of blood clots, studies have not looked at the combined risk of these factors together on blood clot prevalence. Women given new insight into blood clot risk 2023-09-19T04:00:00Z While recovering she discovered she had a type of cancer that would have grown and thrived on one of the major hormones in pregnancy - oestrogen. 'The baby I lost to miscarriage saved my life' 2022-12-06T05:00:00Z Authorities told her to remove breast tissue that had formed since she started taking oestrogen, which she got without prescription from another country. World Cup 2022: 'I am very afraid', says Qatari transgender woman 2022-12-01T05:00:00Z As women approach the menopause - when their periods permanently stop - their levels of the hormone oestrogen fluctuate and drop. NHS talking therapy recommended for menopause symptoms 2023-11-16T05:00:00Z This minimises the amount of oestrogen absorbed by other parts of the body, but means those treatments don't relieve other symptoms like hot flushes. Hormone replacement therapy and menopause: What you need to know about HRT 2022-09-07T04:00:00Z Hormone levels are changing - specifically oestrogen, which controls the menstrual cycle. What is the menopause and what are the signs? 2022-10-17T04:00:00Z As women approach the menopause, their levels of the hormone oestrogen fluctuate and decline. Hormone replacement therapy and menopause: What you need to know about HRT 2022-09-07T04:00:00Z Serious-shortage protocols that limit dispensing to three months' supply and allow specified alternative products to be supplied if necessary will remain in place for 12 HRT products, including some gels and creams containing oestrogen. HRT tsar returns to role overseeing Covid boosters 2022-08-30T04:00:00Z HRT can be used to add back oestrogen and sometimes other hormones too, such as progesterone, and can ease symptoms some women experience as they go through menopause and help keep bones stronger. NHS talking therapy recommended for menopause symptoms 2023-11-16T05:00:00Z "Tasks involving co-ordination and dexterity are more difficult when oestrogen is low and this can impact things like driving." Driving Tests: Why are more men passing than women? 2022-07-23T04:00:00Z The brain, periods, skin, muscles and emotions are all affected by falling levels of oestrogen. What is the menopause and what are the signs? 2022-10-17T04:00:00Z As oestrogen levels become unstable, people can experience a range of symptoms, such as hot flushes, night sweats, anxiety and joint pain. Hormone replacement therapy and menopause: What you need to know about HRT 2022-09-07T04:00:00Z Cancer involving the hormone oestrogen is called oestrogen-receptor positive, or ER positive breast cancer. Incurable breast cancer: Gene drug may give patients more time, study finds 2022-06-05T04:00:00Z For most, the cycle is about 28 days, with four phases, during which the two main sex hormones, oestrogen and progesterone, ebb and flow, producing varying levels of energy: Jessica Ennis-Hill: Why I now train around my period 2022-05-26T04:00:00Z The British Menopause Society reports that deliveries by a manufacturer of one oestrogen gel have nearly doubled so far this year, yet still have not been able to match the "continuing extraordinary demand". HRT: Women turn to black market for menopause symptoms treatment 2022-04-29T04:00:00Z With production of oestrogen having stopped altogether, there is a long-term effect on the bones and heart. What is the menopause and what are the signs? 2022-10-17T04:00:00Z HRT tops up the oestrogen levels in a woman's body and can help alleviate these symptoms. Hormone replacement therapy and menopause: What you need to know about HRT 2022-09-07T04:00:00Z The British Menopause Society advises women who are experiencing difficulty obtaining oestrogen gel to consider other HRT preparations, even if they are not an exact match. Sleepless nights for women due to HRT shortage 2022-04-22T04:00:00Z The growth of some breast cancers is linked to the female hormone oestrogen, which fat cells also produce, for example. Excess weight a clear womb-cancer risk 2022-04-19T04:00:00Z She has one patch that contains two hormones - oestrogen and progesterone. 'The menopause made me feel I was disappearing inside myself' 2021-10-29T04:00:00Z This hormone therapy involves taking testosterone, a masculinising hormone, or oestrogen, a feminising hormone. Keira Bell case: What are puberty blockers? 2021-09-17T04:00:00Z The core ingredient is oestrogen but one of the most common forms is combined HRT, where oestrogen is given alongside a synthetic version of the hormone progesterone. Hormone replacement therapy and menopause: What you need to know about HRT 2022-09-07T04:00:00Z Chair of the Women and Equality Committee Caroline Nokes said pharmacy supplies of oestrogen gel had run out in her Hampshire constituency. Sleepless nights for women due to HRT shortage 2022-04-22T04:00:00Z It's a natural part of ageing that usually occurs between 45 and 55 years of age, as a woman's oestrogen levels decline. Early menopause: 'I was grieving that I couldn't have children' 2021-06-04T04:00:00Z Hormone therapy for trans women is designed to lower testosterone levels and raise oestrogen levels to the typical values in women. Valentina Petrillo: 'Better to be a slow happy woman than a fast unhappy man' 2021-06-03T04:00:00Z Women are more likely to trigger a stronger immune response, because the hormone oestrogen is known to enhance the immune system. Covid: Had the jab and feeling bad? Why does it happen? 2021-05-15T04:00:00Z Adding progesterone helps protect the lining of the womb as oestrogen on its own can sometimes increase the chance of womb cancer. Hormone replacement therapy and menopause: What you need to know about HRT 2022-09-07T04:00:00Z Cowell raced competitively after the war but was increasingly uncomfortable with her body - by 1950 she was still living as a man, but taking large doses of oestrogen. Six LGBT+ sportspeople you should know more about 2021-02-01T05:00:00Z She says that such rises and falls become especially dramatic during the perimenopause — the period before the complete onset of menopause — when oestrogen levels fluctuate wildly. Closing the gender gap in migraine research 2020-10-13T04:00:00Z “We found that in the mid-cycle when oestrogen levels were highest, lung exacerbations were also at their highest,” he says. The gender gap in cystic fibrosis 2020-07-28T04:00:00Z Local reports say Ying Ying – in her oestrogen cycle – spent more time in the water and Le Le left more scent markings around the enclosure. In the mood for love: Hong Kong's middle-aged pandas rediscover their mojo 2020-04-07T04:00:00Z But there are also other possibilities as to why the longevity gaps differ in size, including that oestrogen appears to protect the ends of chromosomes from being damaged – a process linked to ageing. Mystery of lifespan gap between sexes may be solved, say researchers 2020-03-03T05:00:00Z One expert, Dr Grainne Coakley, from Sheffield's Gender Identity Clinic, said - with both testosterone and oestrogen tablets - there was an added risk of the clotting of the blood, and also a risk of liver problems. Transgender patients self-medicating over NHS waits 2020-02-17T05:00:00Z The drugs suppress the release of the hormones oestrogen and testosterone, which start being produced in much bigger quantities during puberty. What are puberty blockers? 2020-01-08T05:00:00Z But oestrogen’s effect was not limited to mucosal fluid dynamics in the lungs. The gender gap in cystic fibrosis 2020-07-28T04:00:00Z She suggests that “DHEA might boost fertility directly or as a mediator of oestrogen production”. Testosterone’s role in ovulation 2019-12-30T05:00:00Z Anastrozole blocks the production of the hormone oestrogen, which fuels the growth of many breast cancers. Drug 'can prevent half of breast cancers' 2019-12-12T05:00:00Z The Victoria Derbyshire programme bought four testosterone and oestrogen products online, to send to a laboratory for testing. Transgender patients self-medicating over NHS waits 2020-02-17T05:00:00Z Suppressing oestrogen and testosterone slows or stops these things developing. What are puberty blockers? 2020-01-08T05:00:00Z Unsurprisingly, the oestrogen blocker tamoxifen was shown to inhibit this action. The gender gap in cystic fibrosis 2020-07-28T04:00:00Z But our reading of the evidence indicates that DHEA’s positive effect on fertility is not because it mediates oestrogen production but because it is converted to testosterone. Testosterone’s role in ovulation 2019-12-30T05:00:00Z Today, the biochemistry of this steroid hormone is well known, from its daily fluctuations to its synthesis from cholesterol and occasional conversion to oestradiol, a form of oestrogen. Testosterone book sifts truths from tall tales 2019-10-21T04:00:00Z She argues that an “idiom of distress” frames the modern menopause — that an important component of the condition is anxiety, triggered by concerns about oestrogen deficiency or lowered status. Menopause: life after reproduction 2019-09-30T04:00:00Z “Yes. The paper they use, the ink, there’s something about it that’s got a lot of oestrogen and you ingest it through your skin.” FKA twigs: ‘An incredible woman always in the shadow of a man? I can relate’ 2019-09-28T04:00:00Z If they took oestrogen and progestagen every day for five years, eight of the women would develop breast cancer. Hormone therapy risks 'bigger and last longer' 2019-08-29T04:00:00Z However, oestrogen causes the womb lining to grow, which raises the risk of endometrial cancer. What is the menopause and when does it strike? 2019-08-26T04:00:00Z Indeed, testosterone is often converted into oestrogen, which means that people who routinely inject testosterone often end up growing breasts. Looking for Mr T: the politicisation of testosterone 2019-07-28T04:00:00Z Cancer involving the hormone oestrogen is called oestrogen-receptor positive - or ER positive breast cancer. Breast cancer trial hope to prolong life 2019-06-04T04:00:00Z She’s learned that they can be managed through stress management and diet: it’s important to avoid sugar and foods with oestrogen, she says – soy, dairy, non-organic meat. FKA twigs: ‘An incredible woman always in the shadow of a man? I can relate’ 2019-09-28T04:00:00Z And just taking oestrogen caused an extra case in every 200 women. Hormone therapy risks 'bigger and last longer' 2019-08-29T04:00:00Z It targets a chemical in the brain called neurokinin B, which is known to increase in response to oestrogen deficiency. What is the menopause and when does it strike? 2019-08-26T04:00:00Z The idea that ingesting more oestrogen from soy means you have less testosterone is a complete misunderstanding of how hormones work. Looking for Mr T: the politicisation of testosterone 2019-07-28T04:00:00Z And the body gradually stops producing oestrogen, which controls the whole process. What does the menopause do to the body? 2019-05-17T04:00:00Z Hmm, I say, but when I check later, I discover twigs is right: receipt ink contains BPA, an artificial oestrogen, which can be absorbed through contact. FKA twigs: ‘An incredible woman always in the shadow of a man? I can relate’ 2019-09-28T04:00:00Z However, taking oestrogen alone increases the risk of womb cancer and is normally used only after a hysterectomy. Hormone therapy risks 'bigger and last longer' 2019-08-29T04:00:00Z Doctors currently classify breast cancers based on whether they respond to the hormone oestrogen or targeted therapies like Herceptin. Cancer's 'internal wiring' predicts relapse risk 2019-03-13T04:00:00Z Menopause usually occurs between 45 and 55 years of age, when a woman's oestrogen levels lower. Women cold water swimming for menopause 2019-02-07T05:00:00Z The brain, skin, muscles and emotions are all affected by falling levels of oestrogen. What does the menopause do to the body? 2019-05-17T04:00:00Z It found tablets containing equine oestrogen were linked with a slightly higher risk than other tablets. Some HRT tablets 'higher clot risk' link 2019-01-09T05:00:00Z It's 92% effective based on "typical use" and doesn't contain the oestrogen hormone. Contraception: Which is most effective? 2018-08-29T04:00:00Z I took my new boxes of patches, a pump gel of oestrogen to top up with on the bad days, my precious testosterone, and went home with hope. ‘It feels impossible to beat’: how I was floored by menopause 2018-08-16T04:00:00Z Feeling uncomfortable in your birth gender is another issue that brings some to the clinic, seeking prescriptions for oestrogen or testosterone. From pregnancy to eating disorders: Gavin Francis picks five books on human transformation 2018-05-28T04:00:00Z When oestrogen production stops altogether, there is a long-term effect on the bones and heart. What does the menopause do to the body? 2019-05-17T04:00:00Z The risk of blood clots was 15% higher for the treatments containing oestrogen manufactured from horse urine than for the synthetic oestradiol, for both single and combined hormone treatments. Some HRT tablets 'higher clot risk' link 2019-01-09T05:00:00Z After this communication was obstructed, the tumours made oestrogen receptors. Communications breakdown puts resistant cancer at risk 2018-03-27T04:00:00Z For many months, I think that the bad days come when my oestrogen dips on the last day before I get new patches. ‘It feels impossible to beat’: how I was floored by menopause 2018-08-16T04:00:00Z “Fat tissues will produce an excess of oestrogen,” says Ryan, which leads to reductions in testosterone. Does testosterone make you mean? 2018-03-20T04:00:00Z That's why women are offered hormone replacement therapy, or HRT, which boosts oestrogen levels and helps to relieve symptoms. What does the menopause do to the body? 2019-05-17T04:00:00Z The American study found that key chemicals in the oils boost oestrogen and inhibit testosterone. Essential oils 'make male breasts develop' 2018-03-17T04:00:00Z These drugs lower oestrogen levels and, when taken over five to ten years, they reduce the risk that the cancer will recur. Acupuncture in cancer study reignites debate about controversial technique I put new oestrogen patches on my abdomen. ‘It feels impossible to beat’: how I was floored by menopause 2018-08-16T04:00:00Z She also said the findings should reassure women who still use the hormones - progestogen and oestrogen - that were used in the drug. Hormone pregnancy test 'no link to harm' 2017-11-15T05:00:00Z Normally, the body copes well with temperature changes, but when oestrogen is lacking, the thermostat goes wonky and the brain thinks the body is overheating when it's not. What does the menopause do to the body? 2019-05-17T04:00:00Z The researchers found all eight demonstrated varying degrees of promoting oestrogen and/or inhibiting testosterone properties. Essential oils 'make male breasts develop' 2018-03-17T04:00:00Z Every patient received treatments such as tamoxifen or aromatase inhibitors which block the effects of oestrogen or shut off the hormone's supply. Breast cancer 'can return after 15 years' 2017-11-09T05:00:00Z It feels as though the oestrogen is lifting me slightly. ‘It feels impossible to beat’: how I was floored by menopause 2018-08-16T04:00:00Z As women pass through menopause, they are affected first by the loss of oestrogen, which increases bone breakdown, and then, as they get older, by difficulty creating new bone. Osteoporosis: Staying strong : Nature : Nature Research 2017-10-03T04:00:00Z Well, oestrogen levels in the body don't recover after the menopause. What does the menopause do to the body? 2019-05-17T04:00:00Z Meanwhile, in many parts of India, there aren't enough pathologists to test a woman's breast cancer for the oestrogen receptor. Cancer patients need better care, not just more technology 2017-09-18T04:00:00Z This, she thought, was more thorough than simply blocking oestrogen receptors, as drugs such as tamoxifen did. Angela M. Hartley Brodie (1934-2017) : Nature : Nature Research 2017-08-01T04:00:00Z I wish the urge to better understand the extent of oestrogen’s reach, and the devastation its fluctuation can bring, had happened decades ago. ‘It feels impossible to beat’: how I was floored by menopause 2018-08-16T04:00:00Z For a long time, investigators believed that the sole cause of that severity in women was the dramatic loss of oestrogen, a hormone that is known to protect bones. Osteoporosis: Staying strong : Nature : Nature Research 2017-10-03T04:00:00Z With rising life expectancy, women are now living more than a third of their lives with oestrogen deficiency. What does the menopause do to the body? 2019-05-17T04:00:00Z Those hoping a shot of oestrogen would generate a new kind of comic-book movie - and revive DC's faltering movie universe - might need to lower their expectations. Does Wonder Woman live up to the hype? - BBC News 2017-05-30T04:00:00Z She discovered and developed the first selective aromatase inhibitor — a drug that blocks the synthesis of oestrogen, which fuels the growth of breast-cancer cells. Angela M. Hartley Brodie (1934-2017) : Nature : Nature Research 2017-08-01T04:00:00Z The adhesions are exacerbated by oestrogen; the drug switched it off. ‘It feels impossible to beat’: how I was floored by menopause 2018-08-16T04:00:00Z Men's oestrogen levels decrease as they age, but only slightly. Osteoporosis: Staying strong : Nature : Nature Research 2017-10-03T04:00:00Z In around a year I will start taking oestrogen, which is the female hormone. Transgender teen: 'Never been so sure about anything' - BBC News 2017-05-07T04:00:00Z During the early weeks, most women experience fatigue at some point caused by rising levels of hormones progesterone and oestrogen. Serena Williams: How did she compete while pregnant? - BBC News 2017-04-20T04:00:00Z Her strategy was to rid people with breast cancer of oestrogen. Angela M. Hartley Brodie (1934-2017) : Nature : Nature Research 2017-08-01T04:00:00Z There are receptors for oestrogen all over the body. ‘It feels impossible to beat’: how I was floored by menopause 2018-08-16T04:00:00Z For women such as d'Anjou, the unbalancing starts at menopause, with a drastic loss of oestrogen. Osteoporosis: Staying strong : Nature : Nature Research 2017-10-03T04:00:00Z During those nine months, women experience a flood of oestrogen which is greater than for the whole of the rest of their lives. Pregnancy alters woman's brain 'for at least two years' - BBC News 2016-12-19T05:00:00Z A South Korean study in 2008 said women who received placenta extracts showed improvement in menopausal symptoms linked to reduced oestrogen levels. Placenta shots and fake names: South Korean president's treatments raise eyebrows 2016-12-16T05:00:00Z This was the first molecule able to inhibit the synthesis of oestrogen alone in breast-cancer cells, without interfering with other physiologically important processes or causing toxic side effects. Angela M. Hartley Brodie (1934-2017) : Nature : Nature Research 2017-08-01T04:00:00Z Recently, scientists discovered that oestrogen is also produced in the adrenal glands, breasts, adipose tissue and brain. ‘It feels impossible to beat’: how I was floored by menopause 2018-08-16T04:00:00Z Men's bones are also protected by oestrogen — testosterone is converted to oestrogen with the help of an enzyme called aromatase. Osteoporosis: Staying strong : Nature : Nature Research 2017-10-03T04:00:00Z It is important to remember that women are twice as likely to experience depression as men, reportedly due to “the fluctuation of progesterone and oestrogen levels”, in other words our biological femaleness. The pill is linked to depression – and doctors can no longer ignore it | Holly Grigg-Spall 2016-10-03T04:00:00Z The subheadline explains via a rhetorical question: “If Clinton chooses Warren as her number two, would that break the oestrogen limit at the White House?” Benghazi Without the Shame 2016-06-20T04:00:00Z Together, the Brodies spent the 1970s optimizing aromatase inhibitors and their method of administration, using synthetic compounds and testing them in vivo and in vitro to block oestrogen synthesis. Angela M. Hartley Brodie (1934-2017) : Nature : Nature Research 2017-08-01T04:00:00Z Studies show both success and failure when women are given oestrogen to counter depression. ‘It feels impossible to beat’: how I was floored by menopause 2018-08-16T04:00:00Z One possible way to preserve both the thin dendritic spines in the prefrontal cortex and the multisynapse connections in the hippocampus is to use oestrogen — in women at least. Ageing: Restoration project : Nature : Nature Publishing Group 2016-03-01T05:00:00Z They suggest toxins in tobacco may play a role by disrupting key reproductive hormones, including oestrogen. Smoking 'linked to earlier menopause' - BBC News 2015-12-15T05:00:00Z Among women who carry the mutation, additional factors — including exposure to oestrogen — may shape the risk of disease. Genetics: Relative risk : Nature : Nature Publishing Group 2015-11-17T05:00:00Z As a British physician, Coombes was easier to persuade of the possible benefits of targeting therapies towards oestrogen. Angela M. Hartley Brodie (1934-2017) : Nature : Nature Research 2017-08-01T04:00:00Z I wonder: is my problem not menopause-specific depression, but that the removal of oestrogen leaves me less protected against my natural lows? ‘It feels impossible to beat’: how I was floored by menopause 2018-08-16T04:00:00Z So far, they have found that the latter works best in female monkeys, “if you take oestrogen, you want to take it cyclically and not continuously,” says Baxter. Ageing: Restoration project : Nature : Nature Publishing Group 2016-03-01T05:00:00Z Most breast tumours also show excessive activity by the receptors that respond to the reproductive hormones oestrogen and progesterone, and numerous studies suggest that these hormone receptors influence the response to HER2-targeted drugs. Medicine: Eyes on the target : Nature : Nature Publishing Group 2015-11-17T05:00:00Z King believes this lengthened period of oestrogen exposure increases the risk of hereditary and non-hereditary cancers alike. Genetics: Relative risk : Nature : Nature Publishing Group 2015-11-17T05:00:00Z “One of them is the ER mutation,” he says, referring to a mutation in the oestrogen receptor — a common mutation in breast cancers. Genetics: Big hopes for big data : Nature : Nature Publishing Group 2015-11-17T05:00:00Z The subtype of 'triple-receptor-negative' breast cancer is particularly difficult to treat because these cancers do not respond to signals from any of the breast growth hormones: oestrogen, progesterone and human epidermal growth factor 2. A tumour through time : Nature : Nature Publishing Group 2015-11-17T05:00:00Z In older female rhesus monkeys, treatment with oestrogen increased the density of the thin spines and correlated with enhanced performance in delayed-response tasks2. Ageing: Restoration project : Nature : Nature Publishing Group 2016-03-01T05:00:00Z There are different types of HRT - some with oestrogen only, and others containing progesterone - each with different risks. Loss of confidence in HRT for menopause, say experts - BBC News 2015-11-11T05:00:00Z And in fact, data suggest that feminine features are linked with higher oestrogen levels and hence with fertility. Neuroscience: The aesthetic brain : Nature : Nature Publishing Group 2015-10-06T04:00:00Z The tests showed that Tian Tian’s oestrogen levels had dropped suddenly in the short interval between her two samples that morning. Everything you always wanted to know about panda sex (but were afraid to ask) | Sam Knight 2015-08-25T04:00:00Z Recently, she was present when a trans friend fell sick having injected herself with oestrogen from Mexico. 'I am Alena': life as a trans woman where survival means living as Christopher 2015-07-24T04:00:00Z One of the most successful breast cancer drugs, tamoxifen, bungs up the oestrogen receptor. Drug could help slow half of breast cancers, study suggests - BBC News 2015-07-08T04:00:00Z The drugs work because they put a brake on the cell division and tumour growth driven by oestrogen. Breast cancer hope as hormone shown to slow tumour growth 2015-07-08T04:00:00Z It releases chemical signals to reduce production and it actively breaks down the hormone into oestrogen. Testosterone boost 'could cut deaths' 2015-03-13T04:00:00Z In a urine sample taken that morning at 8.30am, he had noted a small decrease in her oestrogen, but thought little of it. Everything you always wanted to know about panda sex (but were afraid to ask) | Sam Knight 2015-08-25T04:00:00Z If the gonad becomes an ovary, it makes oestrogen, and the lack of testosterone causes the male plumbing to wither. Sex redefined 2015-02-17T05:00:00Z They show that the progesterone receptor and the oestrogen receptor are closely linked and that the progesterone receptor can make the oestrogen receptor less nasty. Drug could help slow half of breast cancers, study suggests - BBC News 2015-07-08T04:00:00Z “It is linked with the cortisol system and this system does interact with the oestrogen system,” mused Kaminsky, “so I suppose it’s possible”. Why Men Are Killing Themselves 2015-02-12T05:00:00Z It stops the female hormone oestrogen fuelling the growth of tumours although the cancerous cells may eventually become resistant to the drug. Bedtime light 'may stop cancer drug' 2014-07-25T04:00:00Z For, as I look at the faces of so many actors, their surfaces pumped up for the cruel high-definition cameras, I just wonder if their oestrogen is depleting as mine is. Endless nips and tucks, Botox and filler: is this what a woman's right to choose has mutated into? 2014-05-14T04:00:00Z Eastman says that the results of testing, analysed by Thomas Osimitz of Science Strategies, a consulting firm in Charlottesville, Virginia, and his colleagues, verified that Tritan's monomers do not bind to oestrogen or androgen receptors. Toxicology: The plastics puzzle 2014-04-16T17:21:06.648Z He said is was remarkable that some of the cancers that formed in one cell type - oestrogen receptor negative luminal cells - resembled common human breast cancer types. Breast cancer 'personal drugs' hope 2014-03-31T06:24:47Z The sensor, or e-Pill, sits in the cow's rumen and uses sonar technology - originally developed for military purposes - to collect information about the animal, including heart rate, temperature, rumination time, rumen acidity and oestrogen levels. Helping feed the world with big data 2014-03-11T00:02:26Z It stops the production of the hormone oestrogen, which fuels the growth of the majority of breast cancers. Drug 'halves' breast cancer risk 2013-12-12T13:30:10Z This form of the disease is usually treated by chemotherapy followed by the drug tamoxifen for five years to block oestrogen receptors. Breast cancer trials 'failing young' 2013-05-31T23:18:11Z Natural oestrogens are small molecules containing several phenolic rings; these bear chemical adornments that bind to a pocket found in oestrogen receptors in the body. Toxicology: The plastics puzzle 2014-04-16T17:21:06.648Z Sex hormones - oestrogen in woman and testosterone in men - fulfil many roles in the body. Can testosterone make you live longer? 2013-02-04T00:38:49Z They reached their peak in northern Nigeria in 2003 - when the immunisation programme was suspended following claims that the vaccine was contaminated with oestrogen and would cause infertility. Polio killings a major setback 2012-12-19T12:55:13Z Aromatase inhibitors, such as anastrozole, stop oestrogen being produced in the first place and are already used as a treatment for breast cancer. Drug 'halves' breast cancer risk 2013-12-12T13:30:10Z The condition can be provoked by an imbalance of the sex hormones oestrogen and testosterone. 'Man boob' surgery on increase 2012-11-28T07:49:37Z These cells are particularly sensitive to oestrogens and oestrogen mimics, allowing the team to study concentrations of BPS down to 10 moles per litre. Toxicology: The plastics puzzle 2014-04-16T17:21:06.648Z The results suggested that dosing the animals with extra oestrogen to would encourage the disease to adapt to a high-oestrogen environment. Mathematical modelling: Forecasting cancer 2012-11-23T15:21:12.853Z When tamoxifen levels grow high enough to occupy most of the available oestrogen receptors, the effect reverses and the drug begins to inhibit the cancer cells' growth. Toxicology: The learning curve 2012-10-24T17:20:39.163Z Since then, ELA scientists have dripped pollutants such as mercury, synthetic oestrogen and sulphuric acid into the lakes to explore their chemical impacts. Test lakes face closure 2012-08-22T17:20:28.163Z Luminal subtypes are associated with expression of oestrogen and progesterone receptors and differentiated luminal epithelial cell markers. Sequence analysis of mutations and translocations across breast cancer subtypes 2012-06-20T17:22:32.787Z The team found that even at these very low levels, BPS triggered the enzyme cascade normally activated by an oestrogen called oestradiol, an effect also seen with BPA. Toxicology: The plastics puzzle 2014-04-16T17:21:06.648Z By guiding evolution's natural resistance mechanism, the cancers that emerged were oestrogen dependent — and were thus treatable with oestrogen-dependent cancer drugs, such as tamoxifen. Mathematical modelling: Forecasting cancer 2012-11-23T15:21:12.853Z Two formalin-fixed biopsies were obtained at baseline and at surgery, and were used to conduct oestrogen receptor and Ki67 immunohistochemistry as previously published. Whole-genome analysis informs breast cancer response to aromatase inhibition 2012-06-20T17:22:05.433Z In particular, we observed clustering of androgen and oestrogen receptors in male samples and showed that androgen-receptor expression was associated with better overall survival. Perspective: Not just for women 2012-05-30T17:51:20.620Z When Harms hits play, an oestrogen molecule snuggles its way into the binding pocket of a receptor roughly 550 million years old. Prehistoric proteins: Raising the dead 2012-03-21T18:20:44.057Z The results, says Watson, were typical of those expected of an oestrogen mimic: inappropriate activation of oestrogen responses, disruption of normal oestrogen-response pathways, and eventual cell death. Toxicology: The plastics puzzle 2014-04-16T17:21:06.648Z Other drugs block an enzyme called aromatase that the body uses to produce oestrogen. Cancer: Solving an age-old problem 2012-02-29T18:21:13.613Z Facial appearance is a cue to oestrogen levels in women. Framing and definitions: are you maternal enough to be a woman? 2011-10-11T14:15:05.377Z Researchers at the Cancer Research UK Cambridge Research Institute found that some of these oestrogen negative tumours were instead influenced by male hormones. Breast cancer prostate drug hope 2011-06-25T01:25:08Z Until, that is, the chemical industry started pumping out hundreds of substances containing such aromatized rings, which the oestrogen receptor unwittingly bound. Prehistoric proteins: Raising the dead 2012-03-21T18:20:44.057Z Ideally, says Watson, the next generation of chemicals would be tested for effects on oestrogen signalling before widespread deployment in food containers. Toxicology: The plastics puzzle 2014-04-16T17:21:06.648Z They lower oestrogen levels, slowing or stopping the growth of oestrogen-related tumours. Cancer: Solving an age-old problem 2012-02-29T18:21:13.613Z "Girls who start their periods earlier are producing oestrogen for longer periods of time, although those who start their periods early normally finish early, but then they may start taking hormone replacement therapy." Poorer girls start periods early 2011-05-28T01:01:33Z Tamoxifen is used to treat tumours fuelled by the female hormone oestrogen Women who cut short their Tamoxifen treatment before the recommended full five years risk their breast cancer returning, experts warn. 'Stay on tamoxifen' women told 2011-03-22T03:49:28Z That activist legacy bleeds into his work today, for example in his focus on the oestrogen receptor, which is corrupted by many pollutants. Prehistoric proteins: Raising the dead 2012-03-21T18:20:44.057Z Obesity most likely increases the risk of cancer by raising levels of hormones such as oestrogen and insulin in the body. 'One in eight' breast cancer risk 2011-02-04T11:39:42Z Targeted drugs that block the receptor stop cancer growth by preventing oestrogen from binding to the receptor. Cancer: Solving an age-old problem 2012-02-29T18:21:13.613Z Levels of oestrogen in the body are also influenced by diet and, therefore, body weight. Poorer girls start periods early 2011-05-28T01:01:33Z There's so much male energy coursing through JC Chandor's promising financial crisis thriller Margin Call that by the end of it you'd be clamouring for an oestrogen bath, if such a thing were to exist. Margin Call is a fine crash movie, but no banker 2011-01-25T12:06:31Z But when he runs a simulation of the same receptor with those two mutations, the oestrogen never finds a comfortable spot. Prehistoric proteins: Raising the dead 2012-03-21T18:20:44.057Z Writing in Cancer Prevention Research, they said oestrogen helped pre-cancerous cells move and divide by triggering the activity of an enzyme. Oestrogen 'may fuel oral cancer' 2011-01-04T07:58:08Z Indeed, a 2009 study suggested that oestrogen may have as much to do with aggressive behaviours in male mice as testosterone does. A licence for chauvinism 2010-09-17T07:00:00Z Just possibly, the trader’s finger should be pointing at oestrogen, not testosterone. Sex hormones: For the birds 2010-06-10T10:39:00Z “Masculinisation of neural pathways in response to the testosterone surge at birth proceeds primarily under the control of oestrogen,” they conclude. Behaviour of the sexes: The hormone of laddishness 2010-04-29T11:22:00Z This evolutionary story also sheds light on why the oestrogen receptor is now vulnerable to the threats against which Thornton campaigned in his former life. Prehistoric proteins: Raising the dead 2012-03-21T18:20:44.057Z We can give you some other pills that will give your body the oestrogen it ought to be producing. Identity The oestrogen receptor achieves this by binding substances that contain a chemical structure called an aromatized A ring. Prehistoric proteins: Raising the dead 2012-03-21T18:20:44.057Z |
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