| 单词 | neuronal |
| 例句 | “For a materialist,” Lightman writes, “death is the name that we give to a collection of atoms that once had the special arrangement of a functioning neuronal network and now no longer does so.” Must Science Conflict With Spirituality? 2018-06-25T04:00:00Z Out on the water, his passenger’s neuronal activity resolved into a pleasing if possibly illusory tableau of blue sky, gentle breeze and cawing sea gulls. Daniel Dennett, Author of ‘Intuition Pumps and Other Tools for Thinking’ 2013-04-29T21:49:23Z Our medical skills – neuronal, bone, and vascular – Promise to stand the test of time! Style Invitational: Dead letters — our annual obit poem contest 2015-12-30T05:00:00Z Genes direct neuronal development, neurons assemble into brain circuits. Human behaviour: is it all in the brain – or the mind? 2013-06-29T23:05:40Z It suggested that the lack of neuronal activity in this part of the brain was a factor in murderous behavior. This is your brain on murder: What the mind of a psychopath looks like 2014-03-09T18:30:00Z I no longer think it’s all insanity or temporary insanity that can be explained by various breakdowns in the neuronal circuitry or something. Tom Frank interviews Barbara Ehrenreich: “You’re the anti-Ayn Rand” 2014-04-06T11:00:00Z Carr argues that modern neuroscience, which has revealed the "plasticity" of the human brain, shows that our habitual practices can actually change our neuronal structures. The internet: is it changing the way we think? 2010-08-14T23:05:00Z An opening installation by the artist Daniel Canogar drapes the hallway with 1,500 pounds of recycled wire as beams and stroboscopic bursts of light dance over it, creating a corridor of firing neuronal networks. Glimpsing the Brain?s Powers (and Limits) 2010-11-19T18:00:00Z In animal models, decreasing or blocking the production of niacin in the brain promotes neuronal damage and cell death. Diet can influence mood, behavior and more — a neuroscientist explains 2022-09-09T04:00:00Z Simply a “center of narrative gravity,” a convenient fiction that allows us to integrate various neuronal data streams. Daniel Dennett, Author of ‘Intuition Pumps and Other Tools for Thinking’ 2013-04-29T21:49:23Z The death is far too vast to analyze at the micro, individual or neuronal level. “I should be among the dead”: Young, white, and economically advantaged, I was hungry for meaning and found heroin instead 2015-12-30T05:00:00Z Those advances – most notably the drastic cooling of the corpse to slow neuronal deterioration and the monitoring and maintenance of oxygen levels to the brain – have not yet become accepted possibilities in the medical profession. Sam Parnia – the man who could bring you back from the dead 2013-04-06T21:00:01Z But before the onset of neuronal damage and the loss of axonal potential, I was fully alive, and liked to call myself an improbable survivor. The drugs do work: my life on brain enhancers 2013-05-03T22:00:00Z "Co-author Shankar Chinta, PhD, started screening natural compounds in neuronal cells and MIC came up as a major hit," she said. New drug-like molecule extends lifespan, ameliorates pathology in worms and boosts function in mammalian muscle cells 2023-11-13T05:00:00Z In this model, a transient inflammation causes neuronal plasticity, which results in persistence of pain after a subsequent inflammatory stimulus; a perfect model to study what goes wrong during pain resolution. Disturbances in sensory neurons may alter transient pain into chronic pain 2023-11-08T05:00:00Z They found that while all neuronal spiking was indeed low during the down states, even during up states when sensory signals were measurable in STG they still failed to go beyond that region. Anesthesia blocks sensation by cutting off communication within the cortex 2023-11-08T05:00:00Z “This is the first genetically defined neuronal pathway, which regulates fainting” by triggering the Bezold-Jarisch reflex, Augustine says. Heart-brain link offers new potential explanation for fainting 2023-11-01T04:00:00Z They signal to neuronal progenitors whether they should become neurons that function in the front of the brain or the rear part of the spinal cord for example. Controlling organoids with light 2023-10-30T04:00:00Z However, among the genes, those associated with neuronal axons stood out as a group. New clues to early development of schizophrenia 2023-10-24T04:00:00Z The DNA held instructions for producing NeuroD1, a protein that induces neuronal conversion. Converting brain immune cells into neurons helps mice recover after stroke 2023-10-18T04:00:00Z While scientists have made progress in understanding neuronal regeneration, it remains unknown why some neurons regenerate and others do not. New biomarker predicts whether neurons will regenerate 2023-10-16T04:00:00Z Others hypothesize that the performance discrepancy arises from there being two separate neuronal systems to quantify objects. Your Brain Finds It Easy to Size Up Four Objects But Not Five—Here’s Why 2023-10-11T04:00:00Z In the new JNeurosci study, they studied responses in mice through a series of experiments and by isolating neuronal activity. How do our brains tell us what went wrong? 2023-10-06T04:00:00Z Meanwhile, no changes were observed in ABCA7 levels in a neuronal cell line following cholesterol loss. Protein that could help defeat Alzheimer's and increase productive lifespan 2023-10-05T04:00:00Z Furthermore, motor neurons in the brain expand and contract depending on how often they are exercised – a neuronal reflection of "use it or lose it." Psychedelics plus psychotherapy can trigger rapid changes in the brain. Here's how 2023-10-06T04:00:00Z The pattern also included some genes that had never been previously implicated in neuronal regeneration. New biomarker predicts whether neurons will regenerate 2023-10-16T04:00:00Z Analysis of the participants’ neuronal activity showed that neurons specializing in numbers of four or less responded very specifically and selectively to their preferred number. Your Brain Finds It Easy to Size Up Four Objects But Not Five—Here’s Why 2023-10-11T04:00:00Z Jay Piccirillo, an otolaryngologist at Washington University School of Medicine in St. Louis, likens its complexity, with its many neuronal connections, to Times Square. The study of smell loss still struggles for support 2023-10-04T04:00:00Z Herbst suspects that purring is probably driven by a combination of neuronal control and self-sustaining oscillation—but it will be difficult to ever know for certain. How do cats purr? New finding challenges long-held assumptions 2023-10-03T04:00:00Z It's only the 5-HT2A receptor inside the cell that facilitates rapid change in neuronal structure. Psychedelics plus psychotherapy can trigger rapid changes in the brain. Here's how 2023-10-06T04:00:00Z "Validating the results against many sets of data from completely different lines of research tells us that we've uncovered something fundamental about the underlying biology of neuronal regeneration," said Zheng. New biomarker predicts whether neurons will regenerate 2023-10-16T04:00:00Z This is the first time that researchers have deciphered a neuronal network in which one cell type performs the same computation at all network levels. Distributed workload in the fly brain 2023-10-02T04:00:00Z However, the link between biological rhythm and neuronal degeneration remains unclear. Parkinson's: Are our neurons more vulnerable at night? 2023-09-28T04:00:00Z During development, the retinal ganglion cells also generate their own neuronal activity. Vision in the brain: Hardwired for action 2023-09-28T04:00:00Z To capture its prey, the anemone larvae use specialised stinging cells and a simple neuronal network. Did animal evolution begin with a predatory lifestyle? 2023-09-29T04:00:00Z They perform the calculation steps of the neuronal network in sequence, one after the other, differentiating between processor and memory. Efficient training for artificial intelligence 2023-09-22T04:00:00Z "Up to that point, we didn't know any network in which the same neuronal computation is performed at each level and even by the same cell type." Distributed workload in the fly brain 2023-10-02T04:00:00Z These results are especially intriguing, Bielecki says, because they suggest learning is an “integral part of neuronal function,” and possibly something that evolved early on and conserved across different animal species. No brain, no problem. Jellyfish learn just fine 2023-09-22T04:00:00Z "In lakritz, all types of neuronal cells formed at the right place and numbers, only the speed of differentiation was slightly off." Vision in the brain: Hardwired for action 2023-09-28T04:00:00Z The authors say understanding that re-establishing the projections of specific neuronal subpopulations to their natural target regions holds significant promise for the development of therapies aimed at restoring neurological functions in larger animals and humans. Scientists regenerate neurons that restore walking in mice after paralysis from spinal cord injury 2023-09-21T04:00:00Z Gray matter is the tissue that contains most of the brain's neuronal cell bodies and help us process information and govern our muscles. Exposure to plasticizers in pregnancy associated with smaller volumetric measures in the brain and lower IQ in children 2023-09-20T04:00:00Z Inhibition between two oppositely tuned channels, as in motion opponency, is a universal principle of neuronal networks. Distributed workload in the fly brain 2023-10-02T04:00:00Z Sensitive electrophysiological measurements confirmed spontaneous nerve-like activity taking place in the 3D neuronal networks in addition to responses evoked by electrical and drug stimulation. Researchers 'bioprint' living brain cell networks in the lab 2023-09-19T04:00:00Z This way they can remotely control neuronal activity, provided they find ways to stimulate the neurons from the outside with light, a task made easy in zebrafish due to their small size and transparency. Vision in the brain: Hardwired for action 2023-09-28T04:00:00Z Imagine two workers in a neuronal recycling plant. Newly discovered trigger of Parkinson's upends common beliefs 2023-09-15T04:00:00Z The presence of some of these neuronal genes in the cells of placozoans and their absence in ctenophores raises fresh questions about the evolutionary trajectory of neurons. Tiny sea creatures reveal the ancient origins of neurons 2023-09-19T04:00:00Z I had bet Chalmers a case of fine wine that these neural footprints, technically named the neuronal correlates of consciousness, would be unambiguously discovered and described by June 2023. What Does It ‘Feel’ Like to Be a Chatbot? 2023-09-08T04:00:00Z If your brain decides that a fear response is justified in a particular situation, it activates a cascade of neuronal and hormonal pathways to prepare you for immediate action. A psychiatrist explains the neuroscience and physiology of fear 2023-09-06T04:00:00Z "The assembly of neuronal circuits, for example in visual brain areas, is classically considered an experience-dependent process: the neuronal networks are thought to be shaped by visual inputs and neuronal activity." Vision in the brain: Hardwired for action 2023-09-28T04:00:00Z "Now, we need to develop drugs that stimulate this pathway, correct synaptic dysfunction and hopefully prevent neuronal degeneration in Parkinson's." Newly discovered trigger of Parkinson's upends common beliefs 2023-09-15T04:00:00Z High doses altered the shape of neuronal support cells called astrocytes and caused changes in gene expression that suggest disruptions to signaling by the inhibitory neurotransmitter GABA. As cannabis laws relax, neuroscientist warns of its dangers for developing brain 2023-08-31T04:00:00Z Scientists have trained a computer to analyze the brain activity of someone listening to music and, based only on those neuronal patterns, recreate the song. Scientists Recreate Pink Floyd Song by Reading Brain Signals of Listeners 2023-08-15T04:00:00Z To find the specific neuronal structures associated with play, Gloveli and her colleagues decided to focus on the midbrain. Scientists Tickle Rats and Discover Brain's ‘Play Spot’ 2023-07-28T04:00:00Z The experiments of neuronal activity in rodents are important, experts say, because they place the idea of imagination into a physical reality: that of the brain itself. Where Imagination Lives in Your Brain 2023-06-08T04:00:00Z However, the neuronal syncytia seen in the lab dishes and organoids also had some peculiarities that made them stand out from those seen in lungs. Could fused neurons explain COVID-19’s ‘brain fog’? 2023-06-06T04:00:00Z It also tampered with the cytoskeleton, or internal scaffold, of developing neurons, reshaping their long extensions and thereby altering the neuronal wiring in parts of the fetal cerebral cortex. As cannabis laws relax, neuroscientist warns of its dangers for developing brain 2023-08-31T04:00:00Z Seconds after their ventilators were removed, two of the patients’ brains suddenly lit up with a burst of neuronal activity in high-frequency patterns called gamma waves that continued as the heart stopped beating. Burst of brain activity during dying could explain life passing before your eyes 2023-05-01T04:00:00Z The researchers then recorded the relevant neuronal activity before, during and after tickling the rats with a probe attached to the animals’ head. Scientists Tickle Rats and Discover Brain's ‘Play Spot’ 2023-07-28T04:00:00Z Once the electrodes were in the brain, they were connected to a small recording device, which could monitor neuronal activity and which was sealed in a waterproof case, mounted on the fish’s forehead. Why Researchers Turned This Goldfish Into a Cyborg 2023-04-25T04:00:00Z He also says neuronal fusion may be more relevant to other viruses that infect more neurons than SARS-CoV-2 typically does, such as the rabies virus. Could fused neurons explain COVID-19’s ‘brain fog’? 2023-06-06T04:00:00Z And when a person uses cannabis—in any of its edible, dabbable, smokable forms—the drug overwhelms them and disrupts their ability to calibrate neuronal activity. As cannabis laws relax, neuroscientist warns of its dangers for developing brain 2023-08-31T04:00:00Z "At the time, our laboratory at the University of Oregon was deeply involved in assessing nematode food preferences as part of our research on the neuronal basis of economic decision-making," Lockery said. Scientists got tiny worms stoned — and found that they got the munchies just like us 2023-04-20T04:00:00Z The production of factors that spur neuronal growth depends on vitamin D, which has also proved critical to brain cell maturation, says Darryl Eyles, a developmental neurobiologist at the University of Queensland. Vitamin D Supplements Probably Won’t Prevent Mental Illness After All 2023-03-13T04:00:00Z Meanwhile, Veiga-Fernandes and his group have documented clusters of neuronal and immune cells in various tissues and discovered how they work together to sense damage and mobilize immune reactions. Your Brain Could Be Controlling How Sick You Get—And How You Recover 2023-02-27T05:00:00Z SSRIs can help regrow neuronal connections just like psychedelics, only the effect seems to be slower and less dramatic. New research illuminates how the human brain creates its own psychedelic drugs 2023-02-20T05:00:00Z Then, she ran the numbers and came up with a series of estimated neuronal densities for a variety of dinosaur species. Some dinos may have been as brainy as modern primates, controversial study argues 2023-01-10T05:00:00Z And they found that the top 5 percent of genes with the longest transcripts included ones linked with longevity, such as neuronal activity and transcriptional regulation. Aging Is Linked to More Activity in Short Genes Than in Long Genes 2023-01-06T05:00:00Z When compared against the neuronal energy budget of rodents, humans and other primates, a pigeon neuron used three times less energy than the average mammal’s neuron—a “really surprising” result, von Eugen says. Pigeon Neurons Use Much Less Energy Than Those of Mammals 2022-12-22T05:00:00Z Studies suggest these chromosomes also have much broader effects, contributing to processes that include immune system function, neuronal development, disease susceptibility and reactions to drugs. Scientists Created Male and Female Cells from a Single Person 2022-12-21T05:00:00Z They can help regrow neuronal connections just like psychedelics, only the effect seems to be slower and less dramatic. New research illuminates how the human brain creates its own psychedelic drugs 2023-02-20T05:00:00Z Earlier studies measuring glucose uptake in the brain during childhood suggest some of this work is neuronal growth and synapse development. New Human Metabolism Research Upends Conventional Wisdom about How We Burn Calories 2022-12-13T05:00:00Z Shepherd is an associate professor of neurobiology at the University of Utah School of Medicine, and wrote a paper in 2018 for the scientific journal Cell about the neuronal gene known as arc. Ancient viruses gave us a gene called "Arc," and it may explain consciousness 2022-12-06T05:00:00Z Bains found that neuronal connections in a mouse that smells stress pheromones will change to become identical to the mouse that first experienced the stressor. Can stress spread like a virus? What animals tell us. 2022-10-30T04:00:00Z Researchers think their developing brains might benefit from the experience, for example by strengthening neuronal connections involved in muscle coordination. Are these bumble bees playing with toys? 2022-10-27T04:00:00Z These receptors then initiate neuronal signals that the brain later interprets a whiff of coffee, gasoline or perfume. AI Predicts What Chemicals Will Smell like to a Human 2022-10-27T04:00:00Z These electrodes both stimulate the cells and record changes in neuronal activity. Neurons in a Dish Learn to Play Pong 2022-10-14T04:00:00Z “We conceived the drug to try to target pathways of neuronal death,” he said, “and neuronal death is an important part of not just A.L.S. but potentially many diseases.” Price of New A.L.S. Treatment Will Be $158,000 Per Year, Maker Says 2022-09-30T04:00:00Z This poorly studied second phase, called “stretch growth,” continues as the distance between the neuronal cell bodies and their targets increases. Giraffes vs. Blue Whales vs. Dinosaurs: Contest Reveals Which One Builds Its Nervous System Fastest to Evade Predators 2022-09-29T04:00:00Z Topology has many precise methods to count holes in higher-dimensional shapes—an ability that turns out to be helpful in studying the brain's neuronal activity. How Squishy Math Is Revealing Doughnuts in the Brain 2022-09-26T04:00:00Z I stared in disbelief, stunned that my neuronal wiring could have rerouted around this large, oblong hole where my temporal lobe should have been in the space behind my left temple and eye socket. The Curious Hole in My Head 2022-09-04T04:00:00Z “The fact that they so nicely resemble the electrical operation of neurons makes them ideal for physical and electrical coupling with neuronal tissue,” Santoro says, “and ultimately the brain.” Making Computer Chips Act More like Brain Cells 2022-08-29T04:00:00Z This neuronal death can cause many different symptoms—depending on the brain area affected— including headache, muscle weakness or paralysis, speech disturbances, sensory problems, memory loss, and confusion. Biology for AP Courses 2022-06-09T00:00:00Z Indeed, every 3-cm increase in axon length is calculated to add more than double the volume of the neuronal cell body to the axon each day. Giraffes vs. Blue Whales vs. Dinosaurs: Contest Reveals Which One Builds Its Nervous System Fastest to Evade Predators 2022-09-29T04:00:00Z The graph of neuronal connections is a weblike mess: neurons are abundant and richly interwoven. How Squishy Math Is Revealing Doughnuts in the Brain 2022-09-26T04:00:00Z But typical neuronal responses, such as those involving glutamate, happen within milliseconds. Newfound Molecular Switch Signals a Thumbs-up or Thumbs-down in the Mouse Brain 2022-08-12T04:00:00Z Once nestled in the neuronal cells, the coronavirus was able to continue replicating. COVID Virus May Tunnel through Nanotubes from Nose to Brain 2022-07-20T04:00:00Z Glia are non-neuronal cells in the nervous system that support neuronal development and signaling. Biology for AP Courses 2022-06-09T00:00:00Z The neuronal cell body that maintains that long fiber must be quite large, possibly several hundred micrometers in diameter, making it one of the largest cells in the body. Anatomy and Physiology 2013-06-19T00:00:00Z The specific pattern of holes revealed a high level of organization in the neuronal response; this complexity may indicate a fundamental feature of thought processes. How Squishy Math Is Revealing Doughnuts in the Brain 2022-09-26T04:00:00Z There is no interpreter in the brain to assign meaning to these changes in neuronal firing patterns. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z By incorporating other neuronal firing patterns in the brain, Mass says future neuromorphic setups may even one day begin to explore how the multitude of neuronal firing patterns work together to produce consciousness. Microchips that mimic the human brain could make AI far more energy efficient 2022-05-20T04:00:00Z When a neuronal membrane is depolarized to at least the threshold of excitation, an action potential is fired. Biology for AP Courses 2022-06-09T00:00:00Z The simple, single neuronal connection is the basis of somatic reflexes. Anatomy and Physiology 2013-06-19T00:00:00Z Instead, he used electrodes placed on the cortical surface that detect the averaged activity of neuronal populations. Brain-Reading Devices Help Paralyzed People Move, Talk and Touch 2022-04-22T04:00:00Z Fluctuations in neuronal activity are meaningful only for the scientist who is in the privileged position of observing both events in the brain and events in the outside world and then comparing the two perspectives. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z To glean insights from the hoverfly, the team spent more than a decade carefully studying the neuronal pathways of its eyes and measuring their electrical responses to light. AIs Spot Drones with Help from a Fly Eye 2022-04-20T04:00:00Z The ectoderm forms epithelial cells and tissues, and neuronal tissues. Biology for AP Courses 2022-06-09T00:00:00Z The neurotransmitter is cleared from the synapse either by enzymatic degradation, neuronal reuptake, or glial reuptake. Anatomy and Physiology 2013-06-19T00:00:00Z This patient had a very strong positive result for this antibody, which attacks something known as neuronal intermediate filaments in the brain. He Could Barely Walk, and He Was Seeing Double. What Was Wrong? 2022-02-16T05:00:00Z The term “grounding” refers to the ability of the brain's circuits to assign meaning to changes in neuronal firing patterns that result from sensory inputs. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z Based on neuronal firing patterns, algorithms can infer intended body movements in patients with paralysis of their limbs, illuminating the unconscious brain-body dynamic. Mind from Matter 2022-02-01T05:00:00Z Spinocerebellar ataxia, for example, leads to neuronal death in the cerebellum. Biology for AP Courses 2022-06-09T00:00:00Z Signaling begins when a neuronal action potential travels along the axon of a motor neuron, and then along the individual branches to terminate at the NMJ. Anatomy and Physiology 2013-06-19T00:00:00Z “We record the hippocampal neuronal activity while the patients are performing tasks in the EMU for a period of about one week after the surgery.” Cells Deep in Your Brain Place Time Stamps on Memories 2021-12-29T05:00:00Z Instead the brain organizes itself into a vast repertoire of preformed patterns of firing known as neuronal trajectories. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z They watch for signs of waning neuronal health and, when cells in decline are spotted, release neurochemicals that initiate an inflammatory response. How Staying Physically Active May Protect the Aging Brain 2021-12-01T05:00:00Z Based on what you know regarding neuronal signaling, explain how the sensation of touch is blocked from signaling to the brain. Biology for AP Courses 2022-06-09T00:00:00Z The apneustic center is a double cluster of neuronal cell bodies that stimulate neurons in the DRG, controlling the depth of inspiration, particularly for deep breathing. Anatomy and Physiology 2013-06-19T00:00:00Z "In a severe hypoxic environment, when neuronal activity has completely ceased, the photosynthetic O2 reliably provoked a restart and rescue of neuronal activity," the authors wrote. What if humans didn't need to breathe? A study on algae's ability to oxygenate cells raises eyebrows 2021-10-23T04:00:00Z Learning takes place, rather, through a process of matching the preexisting neuronal trajectories to events in the world. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z The second division, between neuronal and nonneuronal types, separates neurons from “support” cell types, collectively termed “glial cells.” An Inventory of All the Brain Cells That Let You Run, Jump and Roll 2021-10-06T04:00:00Z An increase in blood electrolyte levels results in a neuronal signal being sent from the osmoreceptors in hypothalamic nuclei. Biology for AP Courses 2022-06-09T00:00:00Z Another study investigating a drummer's ability to perform complex motor tasks with their two limbs independently found that drummer brains are wired differently, having a "more efficient neuronal design of cortical motor areas." Drummer jokes got it wrong: Why drummers are smarter, healthier, and live longer lives 2021-08-29T04:00:00Z White matter is made up of axons, long neuronal projections that transmit impulses. Stuttering Stems from Problems in Brain Wiring, Not Personalities 2021-08-09T04:00:00Z In its basic version, models of blank slate neuronal networks assume a collection of largely similar, randomly connected neurons. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z When nicotine binds to neuronal receptors in a brain region called the habenula, Kenny found, it prompts the pancreas to release glucagon, a hormone that raises blood sugar. Newly detailed nerve links between brain and other organs shape thoughts, memories, and feelings 2021-06-10T04:00:00Z The hypothalamus contains autonomic centers that control endocrine cells in the adrenal medulla via neuronal control. Biology for AP Courses 2022-06-09T00:00:00Z It is a time of rapid brain growth and neuronal fine-tuning when young people are especially sensitive to social cues and rewards. Adolescent Brains Are Wired to Want Status and Respect: That’s an Opportunity for Teachers and Parents 2021-05-05T04:00:00Z Spontaneous fluctuations are neuronal activities that occur in the brain even when no external stimulus or mental behavior correlates to them. Artificial intelligence research may have hit a dead end 2021-04-30T04:00:00Z The presumption is that brain circuits are highly plastic and that any arbitrary input can alter the activity of neuronal circuits. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z The research team found that there is a relationship between the neuronal activity in the part of the brain that controls motivation and the part of the brain that controls motor function. Closing the recovery gap for paralysis patients | Provided by Pushing Boundaries 2021-04-23T04:00:00Z A component of a brain cell receptor called NMDA, key to neuronal communication, is among the proteins that switch forms. Brain cell clusters, grown in lab for more than a year, mirror changes in a newborn’s brain 2021-02-22T05:00:00Z But she says the origins of the disorder lie in complex circuits of the brain that coordinate the millions of neuronal connections needed for human speech. COVID Can Cause Forgetfulness, Psychosis, Mania or a Stutter 2021-01-21T05:00:00Z Another is the gene ARC, expressed in response to neuronal activity in mammals and flies. How viruses shape our world 2021-01-14T05:00:00Z Because of the multitude of connections and their high communication speeds, these elite subnetworks, sometimes described as a “rich club,” remain well informed about neuronal events throughout the brain. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z “As grief unfolds,” she writes, “the brain will develop new neuronal connections — creating the new patterns, the new habits, of a life that is happening without the missing loved one.” How mourning can affect us mentally and even physically — including blood pressure and the immune system 2021-01-07T05:00:00Z For being able to witness, sometimes at consciousness-sapping proximity on account of lockdowns and social distancing, the dual neuronal marvels of my five-year-old’s developing theory of mind and my one-year-old’s first steps. What We’re Thankful for at Scientific American 2020-11-25T05:00:00Z The team also administered nitroglycerine to rats, a common animal model, and looked at neuronal activity in regions of the brain that are active during migraine. Research round-up: headache 2020-10-13T04:00:00Z What migraine headaches do, he says, is alert a person that something is wrong with their brain — in this case, an event that causes a wave of reduced neuronal activity to pass through it. A richer view of aura 2020-10-13T04:00:00Z Even an inexperienced brain has a vast reservoir of neuronal trajectories at the ready, offering opportunities to match events in the world to preexisting brain patterns without requiring substantial reconfiguring of connections. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z Inhibition is crucial for keeping neuronal activity in the optimal range for encoding information, minimizing the brain’s energy use and computing useful neuronal outputs. Brain’s immune cells put the brakes on neurons 2020-09-29T04:00:00Z The scientists then implanted electrodes in the crows’ brains to record their neuronal signals as they responded. Newfound brain structure explains why some birds are so smart—and maybe even self-aware 2020-09-24T04:00:00Z This result suggests a unique subjective experience was being manifested through neuronal activity. Bird Brains Are Far More Humanlike Than Once Thought 2020-09-24T04:00:00Z Vuong et al.1 report that these metabolites aid normal wiring by neuronal projections called axons that connect brain regions called the thalamus and the cortex. Maternal microbes support fetal brain wiring 2020-09-22T04:00:00Z As brain complexity increases, more intricate connections and neuronal computations insert themselves between motor outputs and sensory inputs. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z Seizures were not observed in wild-type animals receiving the same drugs, indicating that microglia normally exert a brake on neuronal activity. Brain’s immune cells put the brakes on neurons 2020-09-29T04:00:00Z This generated low-frequency neuronal oscillations, similar to those seen in mice that receive ketamine. The brain rhythms that detach us from reality 2020-09-15T04:00:00Z This includes changing the neuronal structure, which can reduce the number of synaptic contacts that neurons have with one another. PTSD expert Seth Norrholm: Americans "are being psychologically abused by Donald Trump" 2020-09-11T04:00:00Z Building up on a previous study, Haibo Zhou, a postdoctoral researcher in Hui Yang's lab, and colleagues, set up a method to convert non neuronal brain cells called "glia" into neurons. New research uses CRISPR gene editing to grow new neurons in diseased brains 2020-09-08T04:00:00Z This disengaged mode of neuronal activity provides access to an internalized virtual world of vicarious or imagined experience and serves as a gateway to a variety of cognitive processes. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z Together, these observations implicate ADO as the microglia-derived factor that dampens neuronal activity. Brain’s immune cells put the brakes on neurons 2020-09-29T04:00:00Z It can be triggered by the drug ketamine, and can occur before a seizure in epilepsy. a, Optogenetic techniques can modulate neuronal activity in response to light. The brain rhythms that detach us from reality 2020-09-15T04:00:00Z It remains an open question whether this neuronal circuit is also sensitive to violet light. Light-activated neurons deep in the brain control body heat 2020-09-01T04:00:00Z Reducing PTBP1 levels presumably reverted glia to unspecified stem cells, which adopted varied neuronal identities based on which glia were targeted and the environmental signals they received. New research uses CRISPR gene editing to grow new neurons in diseased brains 2020-09-08T04:00:00Z In contrast, if the neurons' firing is generated by internal brain mechanisms that can support both navigation and memory, the duration of neuronal firing should be similar at all locations, including inside the wheel. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z Another question is to what extent the inhibitory influence of microglia depends on the amount of neuronal excitation occurring. Brain’s immune cells put the brakes on neurons 2020-09-29T04:00:00Z Only the dissociative drugs produced robust oscillations in neuronal activity in a brain region called the retrosplenial cortex. The brain rhythms that detach us from reality 2020-09-15T04:00:00Z The tracer is taken up by the nerves that send impulses to these cells, by the nerves that feed into them, and so on up the neuronal circuit. Light-activated neurons deep in the brain control body heat 2020-09-01T04:00:00Z In these cases, as in neuronal life, memory expresses itself through priming and triggering events that cause the organism or the system to respond in a way that improves overall fitness. The Ocean Carries ‘Memories’ of SARS-CoV-2 2020-08-15T04:00:00Z Moreover, the firing patterns of individual neurons in this neuronal trajectory could not be distinguished from neurons active when the rat was traversing the arms of the maze. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z But they couldn’t look in detail at the important bit in between — the vast quantities of neuronal activity that conceal patterns representing the animal’s mood or desires, and which help it to calibrate its behaviour. Inside the mind of an animal 2020-08-10T04:00:00Z The authors then recorded neuronal activity across multiple brain regions. The brain rhythms that detach us from reality 2020-09-15T04:00:00Z But they couldn’t look in detail at the important bit in between — the vast quantities of neuronal activity that conceal patterns representing the animal’s mood or desires, and which help it to calibrate its behaviour. Daily briefing: Russia approves ‘reckless’ coronavirus vaccine 2020-08-10T04:00:00Z Oligodendrocytes are glial cells that support and insulate long neuronal axons. The Beautiful Things inside Your Head: Winners of the 10th Annual Art of Neuroscience Contest 2020-07-23T04:00:00Z When we sorted individual trials according to the rat's future choice of left or right arms, the neuronal trajectories were uniquely different. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z The system also films them — typically for 90 minutes, generating 4.5 terabytes of data — allowing the experimenters to align movement with neuronal activity second by second. Inside the mind of an animal 2020-08-10T04:00:00Z Second, it will be interesting to understand how protein access to the brain changes with various factors — such as neuronal activity, diet and neurological disease. Unexpected amount of blood-borne protein enters the young brain 2020-06-30T04:00:00Z Both strategies led to conversion of the targeted astrocytes to neuronal cell types. Method to combat Parkinson’s disease by astrocyte-to-neuron conversion 2020-06-23T04:00:00Z The group analysed a marker of neuronal activity to determine the neuronal populations activated during torpor caused by 24 hours of food deprivation. Flipping the switch on the body’s thermoregulatory system 2020-06-10T04:00:00Z These experiments lead us to the idea that the neuronal algorithms that we can use to walk to the supermarket govern internalized mental travel. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z The group differentiated the hESCs into neuronal precursors, then sorted the fluorescing cells from the rest of the population. Parkinson’s disease grafts benefit from well-timed growth factor 2020-05-25T04:00:00Z This rejuvenation improved spatial memory, reversed age-related changes in neuronal gene expression, and increased the birth of new neurons, as well as the density of their dendrites. Five Types of Research, Underexplored until Recently, Could Produce Alzheimer’s Treatments 2020-04-22T04:00:00Z The two groups demonstrated that PTB depletion causes astrocytes to convert to neuronal cell types largely appropriate to the brain region they reside in. Method to combat Parkinson’s disease by astrocyte-to-neuron conversion 2020-06-23T04:00:00Z Researchers relate the activity they observe to what, where or when, but all the hippocampus is doing is efficiently encoding experience into a neuronal sequence. “Event” Cells in the Brain Help Organize Memory into Meaningful Segments 2020-04-13T04:00:00Z As a rat rests in the home cage after a maze exploration, its hippocampus generates brief, self-organized neuronal trajectories. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z In addition to problems with neuronal integration, current approaches to stem-cell differentiation result in a mixed cell population from which only a relatively low percentage of grafted cells become dopaminergic neurons. Parkinson’s disease grafts benefit from well-timed growth factor 2020-05-25T04:00:00Z Is this due to a neuronal "off" switch or does this entail multiple processes researchers are not fully aware of yet? While you sleep, specialized neurons in your brain remember — and forget 2020-04-13T04:00:00Z However, the iDA neurons generated using this approach neither formed the distant neuronal connections found in a healthy brain nor comprehensively restored motor behaviour. Method to combat Parkinson’s disease by astrocyte-to-neuron conversion 2020-06-23T04:00:00Z Because playing an instrument requires many different areas of the brain, it strengthens a variety of neuronal connections. Your Brain Will Thank You for Being a Musician 2020-04-09T04:00:00Z When a seemingly random action offers a benefit to the organism's survival, the neuronal pattern leading to that action gains meaning. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z Binding between LRP1 and tau leads to the uptake of tau into neurons and its spread through connected neuronal networks. A receptor that lets dementia-associated tau proteins into neurons 2020-03-31T04:00:00Z When the authors artificially activated the DMH-to-rMR pathway, they found an increase in neuronal activity and heat production in brown fat. How stress can cause a fever 2020-03-29T04:00:00Z One intriguing question to arise from these studies is why astrocytes are constantly repressing neuronal genes. Method to combat Parkinson’s disease by astrocyte-to-neuron conversion 2020-06-23T04:00:00Z It seems reasonable to suppose that a factor secreted from the gut in response to Hodor activation might affect the neuronal circuits that control feeding in the brain8. A zinc-sensing protein gives flies a gut feeling for growth 2020-03-17T04:00:00Z The assumption was that neuronal computation starts with simple patterns that are synthesized into more complex ones. How the Brain ‘Constructs’ the Outside World 2022-05-31T04:00:00Z Targeting these residues using chemical inactivation prevented neuronal tau uptake, highlighting their importance. A receptor that lets dementia-associated tau proteins into neurons 2020-03-31T04:00:00Z By contrast, artificial activation of the neuronal projections between the two regions elicited a battery of responses, including increases in heart rate, blood pressure, and heat production in brown fat. How stress can cause a fever 2020-03-29T04:00:00Z In experimental animals, very precise stimulation or inhibition of neuronal firing can be achieved by optogenetics. Mind Reading and Mind Control Technologies Are Coming 2020-03-11T04:00:00Z The authors monitored cerebellar neuronal activity while the monkeys learnt, through trial and error, which response would produce a reward for each cue. Research on the cerebellum yields rewards 2020-03-08T05:00:00Z On the other hand, it is clear that brain function involves complex dynamic patterns of neuronal activity at a population level. Why your brain is not a computer 2020-02-27T05:00:00Z Indeed, there is also no evidence that neuronal health is adversely affected in these control brains. A receptor that lets dementia-associated tau proteins into neurons 2020-03-31T04:00:00Z This indicates that H1047R acts ‘cell autonomously’ to regulate neuronal excitability — meaning that it functions within the cell itself rather than acting on a neighbouring cell. Brain tumours manipulate neighbouring synapses 2020-01-28T05:00:00Z This type of technique, once refined, might therefore be used alongside biomarkers of neuronal damage and degeneration for blood-based diagnostic tests, improving our ability to detect Alzheimer’s disease at an early stage. An immune-cell signature marks the brain in Alzheimer’s disease 2020-01-07T05:00:00Z As monkeys improved their performance over trials, the neuronal activity encoding each outcome waned. Research on the cerebellum yields rewards 2020-03-08T05:00:00Z The first identified mechanism of pyrethroid resistance in wild Anopheles populations was a phenomenon called knockdown resistance, which involves mutations in a voltage-gated sodium channel protein that reduce neuronal sensitivity to the insecticide4. Malaria-carrying mosquitoes get a leg up on insecticides 2019-12-24T05:00:00Z This might help to unpick the poorly understood role for transmission of physiological tau across neuronal networks. A receptor that lets dementia-associated tau proteins into neurons 2020-03-31T04:00:00Z This suggests that glypican 3 is necessary and sufficient in the context of glioblastoma to regulate seizures by controlling synapse formation in the neuronal tissue around the tumour. Brain tumours manipulate neighbouring synapses 2020-01-28T05:00:00Z Second, there is a neuronal population that is present in high numbers in a structure called the dorsal raphe. Brain states behind exploring and hunting revealed 2019-12-17T05:00:00Z His unproven technique claimed to convert bone-marrow cells into neuronal stem cells for the treatment of neurological conditions such as Parkinson’s disease and muscular dystrophy. The conceptual mistake that lies at the heart of economics 2019-12-12T05:00:00Z The procedure, he said, converted stem cells taken from a person’s bone marrow into neuronal stem cells, which were then infused back into that person. Rogue stem-cell salesman Davide Vannoni dies 2019-12-11T05:00:00Z All are due to neuronal death in the movement-controlling striatum as well as the cerebral cortex. Research Using Brains-in-a-Dish Forces a Radical Rethinking of Huntington’s Disease 2019-12-10T05:00:00Z Enhanced neuronal activity might explain why seizures are associated with glioblastoma. Brain tumours manipulate neighbouring synapses 2020-01-28T05:00:00Z The analysis is limited, but the researchers speculated that the parasites may be affecting neuronal connections in the bugs’ brains and perhaps even interfering with memory in a way that puts the hosts at risk. First the Worm Gets in the Bug’s Head. Then the Bug Drowns Itself. 2019-11-22T05:00:00Z In vertebrate embryos, the first neuronal circuits to respond to sensory information and orchestrate movement are found in the spine2. Cell-tracking pipeline reveals how motor circuits are built 2019-11-19T05:00:00Z You are looking at a small subsection of a reconstruction of the dense neuronal network in the brain of a young mouse. Budding Organs, Science on Blast(s), and Human-Robot Synchronicity: Science GIFs to Start Your Week 2019-11-04T05:00:00Z Overall, their DNA activation is that of less mature neuronal development compared to brain organoids created from healthy people, which may lay the foundation for eventual neurodegeneration. Research Using Brains-in-a-Dish Forces a Radical Rethinking of Huntington’s Disease 2019-12-10T05:00:00Z Seizures are caused by a rise in neuronal activity and are often an early symptom of glioblastoma6. Brain tumours manipulate neighbouring synapses 2020-01-28T05:00:00Z Treatment with these compounds inhibits neuronal degeneration in various models of Huntington’s disease. Strategy to selectively remove mutant proteins could combat neurodegeneration 2019-10-29T04:00:00Z By engulfing and degrading unwanted synapses, the cells ensure that neuronal connections are pruned or maintained as needed8. Gut microbes regulate neurons to help mice forget their fear 2019-10-22T04:00:00Z Information in the brain is thought to be encoded as complex patterns of electrical impulses generated by thousands of neuronal cells. A breakthrough method that became vital to neuroscience 2019-10-21T04:00:00Z Thus nicotine, by stimulating mHb neurons in a TCF7L2-dependent manner, engages neuronal signalling to the pancreas and so alters blood glucose levels. Brain-to-pancreas signalling axis links nicotine and diabetes 2019-10-15T04:00:00Z This pattern might explain how certain PIK3CA variants drive neuronal excitability and seizures. Brain tumours manipulate neighbouring synapses 2020-01-28T05:00:00Z First, patient-derived neurons treated with each of the compounds showed significantly less shrinkage, degeneration of neuronal projections and cell death than was seen in untreated neurons. Strategy to selectively remove mutant proteins could combat neurodegeneration 2019-10-29T04:00:00Z They show that overall neuronal excitation is a major determinant of lifespan, and that it is higher in short-lived individuals and lower in the long-lived. Moderation of neural excitation promotes longevity 2019-10-15T04:00:00Z Whole-cell patch clamp proved ideal for studying the collective properties of neurons and neuronal networks in brain slices maintained in vitro. A breakthrough method that became vital to neuroscience 2019-10-21T04:00:00Z These nodes of neuronal communication, researchers show, are where internal preparations for sleep and the effects of our sleep-related behaviors converge. Sleep Deprivation Shuts Down Production of Essential Brain Proteins 2019-10-10T04:00:00Z Those participants had then been put in an fM.R.I. scanner — which detects changes in blood flow associated with neuronal activity — and been shown the most arousing images as well as neutral, nonsexualized ones. What Can Brain Scans Tell Us About Sex? 2019-09-18T04:00:00Z But the skull muffles the reading of neuronal signals. Are brain implants the future of thinking? 2019-09-22T04:00:00Z Adjacent to these postsynaptic densities, in a nearby neuron, the authors noted clusters of vesicles that store neurotransmitter molecules, which are a feature of a neuronal presynaptic zone. Dangerous liaisons as tumour cells form synapses with neurons 2019-09-17T04:00:00Z A challenge in working with more-complex systems such as neuronal networks is that the number of possible confounding factors increases. A breakthrough method that became vital to neuroscience 2019-10-21T04:00:00Z The classification of neuronal cell types in the brain represents a long-standing goal in neuroscience that goes back to the anatomists of the early twentieth century. A recipe book for cell types in the human brain 2019-08-20T04:00:00Z Our ability to sense these things requires an applied force to be turned into an electrical signal in the tiny endings of sensory neuronal cells that suffuse different tissues. A mechanism for touch 2019-08-20T04:00:00Z The scan detects neuronal activity by measuring changes in blood oxygen levels, revealing how different regions of the brain fire and coordinate brainwide neuronal chatter. Brain scans could help personalize treatment for people who are depressed or suicidal 2019-08-20T04:00:00Z The depolarization of glioma cells induced by neuronal activity caused a transient rise of calcium ions in the cytoplasm, which then spread through the network of glioma cells through their gap junctions. Dangerous liaisons as tumour cells form synapses with neurons 2019-09-17T04:00:00Z In people with Huntington’s, there are far too many of these repeats, resulting in abnormally large, mutant huntingtin proteins that cause neuronal damage. Antisense Drugs for Huntington’s, ALS and Prion Diseases Could Meet the Dire Need for Brain Treatments 2019-08-15T04:00:00Z Many of those clusters represent previously defined cell types, but others revealed previously unknown distinctions within broad neuronal classes. A recipe book for cell types in the human brain 2019-08-20T04:00:00Z The authors saw a similar effect in worms in which the expression of a neuronal transcription-factor protein that was previously shown to be required for CNS patterning12 was suppressed. What makes flatworms go to pieces 2019-08-13T04:00:00Z This response also causes transient motor impairments resembling those in Parkinson’s disease and a temporary loss of neuronal dopamine-release sites. Infection triggers symptoms similar to those of Parkinson’s disease in mice lacking PINK1 protein 2019-07-16T04:00:00Z The drugs also help connect neuronal networks, leading to a kaleidoscope of complex emotions, a higher state of consciousness, and deeper observations about the nature of reality and of the self. The Psychedelics Evangelist: A German Financier Wants to Turn Magic Mushrooms Into Modern Medicine 2019-07-09T04:00:00Z Using fluorescent indicators of neuronal activity, it is now feasible to ‘watch’ signals flow through the nervous system of a freely behaving worm in real time10,11. Neural networks mapped in both sexes of the worm 2019-07-02T04:00:00Z Together, these studies challenge long-held assumptions about the discrete laminar organization of neuronal cell types in the cerebral cortex. A recipe book for cell types in the human brain 2019-08-20T04:00:00Z Many of the genes involved in human conditions such as schizophrenia and autism are the same ones that determine neuronal connections in worms, he says. Worm Wiring Diagram May Help Us Understand Our Own Nervous System 2019-07-03T04:00:00Z For instance, if we define a cause as a systematic difference-making factor for the resulting effect, then it’s not clear that the neuronal readiness potentials measured by Libet would qualify as causes of the actions. Free Will Is Real 2019-06-08T04:00:00Z Neighboring genes also tend to be involved in processes altered in autism, such as neuronal signaling or gene regulation — the same pathways that coding mutations disrupt. "Noncoding" Mutations May Play Unexpected Key Role in Autism 2019-06-02T04:00:00Z Low- and high-resolution microscopy images were taken of these sections, revealing the anatomy of a typical section, including the neuronal processes and synaptic connections. Neural networks mapped in both sexes of the worm 2019-07-02T04:00:00Z In this way, the earth’s rotation is reproduced in the dynamics of our neuronal circuits. Meet the Animals That Literally Sleep with One Eye Open 2019-06-01T04:00:00Z Mohebi et al. took the key step of recording both neuronal activity and dopamine release in freely moving rats, although both properties were not recorded in the same animals. Closing in on what motivates motivation 2019-05-21T04:00:00Z The psychological – not just neuronal – level remains hospitable to causal regularities. Free Will Is Real 2019-06-08T04:00:00Z Thanks to neuroscience, we can demonstrate that cognitive-behavioral therapy causes neuronal changes in the brain. The Troubled History of Psychiatry 2019-05-20T04:00:00Z In either case, although the amount of computation is vast, the variety of operations is modest, because ‘multiply–accumulate’ operations dominate across the many synaptic weights and neuronal excitations. A role for optics in AI hardware 2019-05-07T04:00:00Z Furthermore, recent research in humans using functional magnetic resonance imaging indicates that certain patterns of neuronal activity may provide a correlate for consciousness. Part-revived Pig Brains Raise Slew of Ethical Quandaries 2019-04-17T04:00:00Z The authors found that neuronal activity in the VTA of rats was unaffected by an increase in the reward rate, however, suggesting that the motivation-related dopamine release is dissociated from the activation of dopamine neurons. Closing in on what motivates motivation 2019-05-21T04:00:00Z Furthermore, recent research in humans using functional magnetic resonance imaging indicates that certain patterns of neuronal activity may provide a correlate for consciousness9. Part-revived pig brains raise slew of ethical quandaries 2019-04-16T04:00:00Z Llorens-Martín says her team used multiple other proteins associated with neuronal development to confirm that the DCX-positive cells were actually young, and were “very strict,” in their criteria for identifying young neurons. New neurons for life? Old people can still make fresh brain cells, study finds 2019-03-25T04:00:00Z Furthermore, the need to melt the materials to induce a full neuronal reset after every potential excitation event will rapidly consume the large, but finite, switching endurance of the materials. A role for optics in AI hardware 2019-05-07T04:00:00Z What are the cellular underpinnings of the widespread neuronal suppression that promotes feature competition? The influence of a single neuron on its network 2019-03-05T05:00:00Z This evidence for dopamine release in the absence of an increase in activity in dopamine neurons provides further support for the authors’ model that neuronal activity and dopamine release can be dissociated. Closing in on what motivates motivation 2019-05-21T04:00:00Z It might be necessary to apply BrainEx or similar systems to mice or rats, both with and without neuronal activity blockers, to better understand the blockers’ role. Part-revived pig brains raise slew of ethical quandaries 2019-04-16T04:00:00Z Instead of damping things down as they do in the hippocampus, in this fear-promoting region they increase excitability and expand neuronal connections. How Economic Inequality Inflicts Real Biological Harm 2019-02-25T05:00:00Z You may find yourself in a state of doing neither, your neuronal toggle stuck, buzzing, between the two functions. Jasper Johns and the Question of Meaning 2019-02-25T05:00:00Z Does the cortical network use different coding schemes for different behavioural or environmental contexts, in a way that affects the pattern of the neuronal responses9? The influence of a single neuron on its network 2019-03-05T05:00:00Z The procedure also activated the mediodorsal thalamus, a region that receives neuronal projections from the superior colliculus. Biological clues to an enigmatic treatment for traumatic stress 2019-02-12T05:00:00Z “We’ll be putting in a grant application to do this precisely with general motor neuronal disease in mind,” Johnson says. Artificial "Dumbness" May Be a Solution for Engineering Smart Machines 2019-02-12T05:00:00Z The researchers then checked neuronal activity in some of their brains by microscopically probing individual cells in living tissue to measure their electrical and biochemical signals. Outrunning Hunger 2019-01-25T05:00:00Z That resonates with other theories in neuropsychology, which propose that synchronization of neuronal activity in the brain might be correlated with psychosis or depression, says cognitive neuroscientist Robert Knight at the University of California, Berkeley. Pioneering brain study reveals ‘software’ differences between humans and monkeys 2019-01-18T05:00:00Z More importantly, it enabled the authors to categorize neuronal influences according to the degree of similarity between the responses of the manipulated neuron and those of the neurons it affects2,3. The influence of a single neuron on its network 2019-03-05T05:00:00Z These findings, put together, suggest a model in which the extinction and ABS procedures act in tandem to recruit the neuronal pathway that links the superior colliculus and the mediodorsal thalamus. Biological clues to an enigmatic treatment for traumatic stress 2019-02-12T05:00:00Z In all those ailments, the resulting abnormal pileups of proteins somehow become rogue neuronal killers. To halt brain diseases, drugs take aim at protein traffic jams that kill neurons 2019-01-16T05:00:00Z The data also suggest that continued training potentially remodels the neuronal circuitry in ways that endure, which might partly explain why exercise so often helps with long-term weight management. Outrunning Hunger 2019-01-25T05:00:00Z In his definition, free energy in the brain describes the neuronal state that results from the brain’s failure to make a correct prediction; the brain does all it can to avoid free energy. The Brain's Autopilot Mechanism Steers Consciousness 2018-12-19T05:00:00Z In turn, senescent glia affect the ability of neurons to regulate tau phosphorylation and aggregation, ultimately promoting neuronal degeneration. 2018: Choice cuts from this year’s News & Views articles 2018-12-13T05:00:00Z So, the shared resonance in a human brain that achieves gamma synchrony, for example, includes a far larger number of neurons and neuronal connections than is the case for beta or theta rhythms alone. The Hippies Were Right: It's All about Vibrations, Man! 2018-12-05T05:00:00Z “We use this method for connectivity mapping, which requires preservation of neuronal fibres: once you cut them, you lose information,” says Chung. Transparent tissues bring cells into focus for microscopy 2018-12-03T05:00:00Z Animal research suggests that partly blocking certain glutamate receptors increases brain plasticity — the ability of the brain to make new neuronal connections — and corrects some of the abnormalities that result from chronic stress. Opinion | Can We Stop Suicides? 2018-11-30T05:00:00Z Presumably, the oral respiration was less effective because it bypassed the olfactory bulb, Arshamian says, and did not jump-start the same neuronal cascade. Breathing Through the Nose May Offer Unique Brain Benefits 2018-11-20T05:00:00Z When the brain imagines something, the neuronal activity is extremely similar, in location and pattern, to when it does something. With Brain Implants, Scientists Aim to Translate Thoughts into Speech 2018-11-20T05:00:00Z Whenever she tried to pick up an object—a ball, a plastic cone—the array detected a surge of neuronal activity, and the arm backed away, as if repelled by a force field. How to Control a Machine with Your Brain 2018-11-19T05:00:00Z From there, they used sophisticated imaging techniques to compile a comprehensive 3D neuronal survey — of some 72 million cells in all, Ueda says. Transparent tissues bring cells into focus for microscopy 2018-12-03T05:00:00Z However, translating the cellular composition of the brain into biologically meaningful insights will require new strategies for interrogating neuronal function. Single-cell sequencing paints diverse pictures of the brain 2018-10-30T04:00:00Z This would be exciting because one of the limitations of MRI is that it can’t measure neuronal activity directly. The world’s strongest MRI machines are pushing human imaging to new limits 2018-10-30T04:00:00Z The mental image of a pumpkin pie produces activity in the visual cortex very much like that while seeing one; imagining taking a jump shot evokes neuronal activity like actually executing one. With Brain Implants, Scientists Aim to Translate Thoughts into Speech 2018-11-20T05:00:00Z The speaker erupted with a symphonic neuronal burst. How to Control a Machine with Your Brain 2018-11-19T05:00:00Z Many years ago, in a past life, I was a neurobiologist focusing on how neuronal networks are shaped in the living brain. How Augmented Reality and Virtual Reality Can Revolutionize Science 2018-10-30T04:00:00Z The authors injected the cells with fluorescent tracers to track their neuronal projections into distant brain areas. Single-cell sequencing paints diverse pictures of the brain 2018-10-30T04:00:00Z “My research has shown that fish have a strikingly similar neuronal system to mammals,” she told me, adding that until 2002, “it was generally believed fish did not have feelings”. Are we wrong to assume fish can't feel pain? 2018-10-30T04:00:00Z Take, for example, their discussion of our recent study reporting increased neuronal “signal diversity” in the psychedelic state. What Psychedelic Research Can and Cannot Tell Us about Consciousness 2018-10-26T04:00:00Z Moreover, increasing neurogenesis in the earliest stages of the disease may protect against neuronal cell death later in the disease, providing a potentially powerful disease-modifying treatment strategy. How Exercise Might "Clean" the Alzheimer's Brain 2018-10-16T04:00:00Z He and colleagues injected a fluorescent rabies virus, which is transmitted through neuronal synapses, into the colons of mice and waited for the enteroendocrine cells and their partners to light up. Your gut is directly connected to your brain, by a newly discovered neuron circuit 2018-09-20T04:00:00Z Moreover, previous reports10,11 suggest that antibodies targeting neuronal proteins are present at a higher than usual frequency in people with narcolepsy. Put to sleep by immune cells 2018-09-18T04:00:00Z It will also be interesting to understand whether the same glia-derived signals affect both tau pathology and neuronal survival, and whether astrocytes and microglia send the same or distinct signals. Elimination of senescent cells prevents neurodegeneration in mice 2018-09-18T04:00:00Z Among IST Austria’s most prolific teams are those determining how immune cells move and change shape, how plants adapt to changing environments, and how neuronal networks process information. Green shoots 2018-09-18T04:00:00Z Getting a visual read-out of membrane voltage also allows scientists to see electrical signals that inhibit neuronal firing rather than trigger it. A new way to capture the brain’s electrical symphony 2018-09-18T04:00:00Z When we decide to walk, the brain broadcasts commands through parallel neuronal pathways that cascade to executive centres in the lumbar region of the spinal cord1. Reducing neuronal inhibition restores locomotion in paralysed mice 2018-09-16T04:00:00Z This challenges the model that targeting of hypocretin by such T cells is involved in neuronal destruction. Put to sleep by immune cells 2018-09-18T04:00:00Z They find that neuronal expression of mutant tau triggers senescence in glia, the support cells of the brain. Elimination of senescent cells prevents neurodegeneration in mice 2018-09-18T04:00:00Z It also inhibits neurons more reliably than ZipACR, reversibly reducing neuronal firing, on average, to about 30% of the initial rate in mouse brain slices. Protein structures guide the design of a much-needed tool for neuroscience 2018-09-16T04:00:00Z For example, ‘transcranial’ magnetic stimulation involves creating a magnetic field close to the head to alter neuronal activity near the brain’s surface. Can brain-stimulating implants treat some severe cases of autism? 2018-09-14T04:00:00Z Moreover, the researchers showed that CLP290 did not affect the growth of new neuronal projections — recovery was triggered merely by restoring this balance in relay circuits. Reducing neuronal inhibition restores locomotion in paralysed mice 2018-09-16T04:00:00Z Kandel’s work in the 1960s — uncovering the circuitry of learning processes by measuring neuronal activity in the marine mollusc Aplysia — earned him a Nobel prize. Probing the genetics of the mind 2018-08-07T04:00:00Z Experiments in mice and human cell lines show that human tau is required for some of the neuronal damage associated with the disease to occur. The amyloid hypothesis on trial 2018-07-24T04:00:00Z “It does seem plausible that the characteristic distribution of the pathology is related, in part at least, to transmission along neuronal networks.” Ways to stop the spread of Alzheimer’s disease 2018-07-24T04:00:00Z To try to find out which neuronal pathway is responsible for the animals’ improvement, Reti’s team has since turned to optogenetics. Can brain-stimulating implants treat some severe cases of autism? 2018-09-14T04:00:00Z Such intrinsic processes are thought to cooperate with the interneuron’s environment to establish neuronal circuits and brain connectivity in the adult6. Developing neurons are innately inclined to learn on the job 2018-07-22T04:00:00Z As our neuronal networks shrink, so, all too often, do our social networks. Why science education for seniors is a boon for them — and for everyone else 2018-06-30T04:00:00Z Such species or individuals might harbour neuronal mechanisms that are adapted to the lack of social inter-action. A molecular signature for social isolation identified in the brain 2018-06-17T04:00:00Z Others suggest that Olduvai is involved in neuronal stem cell proliferation, a process important in the growth of neural tissue, which is often impaired in similar diseases of the brain. Scientists are untangling our bodies’ genetic “double-edged swords” 2018-06-09T04:00:00Z The device’s current was set high and may have been igniting a confluence of neuronal pathways; that also meant Becky’s batteries were going fast. Can brain-stimulating implants treat some severe cases of autism? 2018-09-14T04:00:00Z One is to use the increasingly refined tools at our disposal to observe and probe the vast coalitions of highly heterogeneous neurons making up the brain to further delineate the neuronal footprints of consciousness. What Is Consciousness? 2018-05-22T04:00:00Z When they drew lines corresponding to the neuronal activity, here is what they saw: a grid. Perspective | How is LeBron James always one move ahead? Let’s ask the scientists. 2018-05-17T04:00:00Z And none of this second generation of mice, which never exercised, sired babies with notably strong neuronal connections. Do Fathers Who Exercise Have Smarter Babies? 2018-05-09T04:00:00Z The researchers found that these neuronal signals curtail the body’s immune response, thus allowing the bacteria to thrive. Flesh-eating bacteria thrive on pain 2018-05-09T04:00:00Z It is those results, generated by layers and layers of neuronal bureaucracy, that we experience as fear, desire, determination, reasoning and decision-making. Review | How does the brain give rise to consciousness? 2018-05-04T04:00:00Z In fact, our bodies are pretty good at regulating their core brain and body temperatures, so the difference of a few degrees outside would not alter neuronal activity. Sound Awake: "Noisy" Neurons May Repeatedly Disrupt Your Sleep 2018-05-01T04:00:00Z When the researchers repeatedly stimulated the animals’ hippocampal neurons, both groups of mice developed stronger neuronal connections — a process thought to be crucial to learning and memory. Why fit fathers sire smarter offspring 2018-04-11T04:00:00Z Stronger neuronal connections there generally mean sharper thinking. Do Fathers Who Exercise Have Smarter Babies? 2018-05-09T04:00:00Z Phagocytosis executes delayed neuronal death after focal brain ischemia. Innate immune memory in the brain shapes neurological disease hallmarks 2018-04-10T04:00:00Z Similarly, immune tolerance reduced levels of neuronal death seven days after the researchers induced stroke in wild-type mice. Immune memory in the brain 2018-04-10T04:00:00Z Consequently, the researchers think newborns may be more susceptible to heat-related fluctuations in neuronal noise. Sound Awake: "Noisy" Neurons May Repeatedly Disrupt Your Sleep 2018-05-01T04:00:00Z He's no different from the rest of us: when you're happy, your body creates endorphins, neuronal signals are sent to your facial muscles and they form a smile. Google's most popular Putin search queries answered 2018-03-18T04:00:00Z There seem to be generic transcriptional programs across neuronal types in the early stages of their development. A mixed model of neuronal diversity 2018-03-04T05:00:00Z I am more of a science-as-a- descriptive-tool kind of person, and see consciousness in a more pragmatic and less fundamental way, as an emergent property of very complex neuronal patterns. The More We Know, the More Mystery There Is 2018-03-04T05:00:00Z In this computational experiment, published in 1999 in Nature Neuroscience, the researchers simulated neuronal connections in the visual cortex—complete with downward connections carrying forecasts and upward connections bringing sensory signals from the outside world. Intelligent Machines That Learn Like Children 2018-02-20T05:00:00Z Together, these results show that a glia–neuron interaction at the perisomatic space of LHb is involved in setting the neuronal firing mode in models of a major psychiatric disease. Astroglial Kir4.1 in the lateral habenula drives neuronal bursts in depression 2018-02-13T05:00:00Z Two of these modules are important for neuronal communication; the other one is involved in the function of mitochondria, which generate energy for cells. Autism Shares Brain Signature with Schizophrenia and Bipolar Disorder 2018-02-08T05:00:00Z This analysis demonstrated a link between the initial diversity of immature neurons and the diversity in mature neuronal subtypes, consistent with the premitotic model. A mixed model of neuronal diversity 2018-03-04T05:00:00Z Meanwhile, genes linked to neuronal firing were turned down in autism, as well as in schizophrenia and bipolar disorder—suggesting that changes in brain cell communication play a role in all three conditions. Major mental illnesses unexpectedly share brain gene activity, raising hope for better diagnostics and therapies 2018-02-08T05:00:00Z When anesthesia takes hold of an animal, the neuronal heartbeat vanishes. Plants, Like People, Succumb to Anesthesia [Video] 2018-01-28T05:00:00Z Glial and neuronal control of brain blood flow. Astroglial Kir4.1 in the lateral habenula drives neuronal bursts in depression 2018-02-13T05:00:00Z Common variants linked to autism and schizophrenia tend to pop up in the three neuronal modules. Autism Shares Brain Signature with Schizophrenia and Bipolar Disorder 2018-02-08T05:00:00Z The group thus showed that mature neuronal properties are already distinguishable in a rough form in newborn neurons. A mixed model of neuronal diversity 2018-03-04T05:00:00Z The science of comparing animals is still evolving, and Herculano-Houzel said it would be great to consistently incorporate neuronal information with studies of behavior. Which animals are smartest: Dogs, cats, or ... raccoons? 2017-12-04T05:00:00Z In most parts of the brain, synaptic strength varies as a function of neuronal firing frequency, a phenomenon known as 'short-term synaptic plasticity'. Synaptotagmin 7 confers frequency invariance onto specialized depressing synapses 2017-10-29T04:00:00Z The drugs act on neuronal receptors to dull pain, but those in the brain stem also control breathing. New painkillers could thwart opioids' fatal flaw 2017-11-16T05:00:00Z Geschwind and his team are exploring how the gene expression patterns relate to neuronal activity. Autism Shares Brain Signature with Schizophrenia and Bipolar Disorder 2018-02-08T05:00:00Z However, the quest to understand neuronal diversity is only just beginning. A mixed model of neuronal diversity 2018-03-04T05:00:00Z Our results reveal that behaviourally opposing locomotor functions in the caudal brainstem were historically masked by the unexposed diversity of intermingled neuronal subpopulations. Locomotor speed control circuits in the caudal brainstem 2017-10-22T04:00:00Z The resulting constant synaptic strength over a wide range of firing frequencies allows for efficient encoding of neuronal firing rates. Synaptotagmin 7 confers frequency invariance onto specialized depressing synapses 2017-10-29T04:00:00Z Activating this protein, which is embedded in neuronal cell membranes, leads to either pain relief or respiratory depression depending on the brain circuit to which it belongs. New painkillers could thwart opioids' fatal flaw 2017-11-16T05:00:00Z Murine intestinal cells expressing Trpm5 are mostly brush cells and express markers of neuronal and inflammatory cells. A single-cell survey of the small intestinal epithelium 2017-11-07T05:00:00Z Resolving these issues will be central not only to addressing the mechanisms that generate neuronal diversity, but also to characterizing and understanding inter-individual differences in circuit structure and function. A mixed model of neuronal diversity 2018-03-04T05:00:00Z Silvia Arber and colleagues now show that in the mouse caudal brainstem, functionally distinct neuronal subpopulations, distinguishable by their neurotransmitter identity, connectivity and location, influence locomotion parameters. Locomotor speed control circuits in the caudal brainstem 2017-10-22T04:00:00Z Axon patterning requires DN-cadherin, a novel neuronal adhesion receptor, in the Drosophila embryonic CNS. Ultra-selective looming detection from radial motion opponency 2017-11-07T05:00:00Z Sensory, motor and cognitive operations involve the coordinated action of large neuronal populations across multiple brain regions in both superficial and deep structures1,2. Fully integrated silicon probes for high-density recording of neural activity 2017-11-07T05:00:00Z These findings implicate Kctd13 in the regulation of neuronal function relevant to neuropsychiatric disorders and clarify the role of Kctd13 in neurogenesis and brain size. Kctd13 deletion reduces synaptic transmission via increased RhoA 2017-10-31T04:00:00Z Here we show that astrocyte morphogenesis in the mouse cortex depends on direct contact with neuronal processes and occurs in parallel with the growth and activity of synaptic circuits. Astrocytic neuroligins control astrocyte morphogenesis and synaptogenesis 2017-11-07T05:00:00Z And the neuronal subtype, which shares genetic features with rare neuroendocrine cancers, has the poorest survival rate. Genetics: A clearer view : Nature : Nature Research 2017-11-07T05:00:00Z Also on the horizon are cultured cells called iN cells, neuronal cells that are generated directly from patients' cells without going through the stem-cell stage. Non-Familial ALS: A tangled web : Nature : Nature Research 2017-10-17T04:00:00Z Sensory, motor and cognitive operations involve the coordinated action of large neuronal populations across multiple brain regions. Fully integrated silicon probes for high-density recording of neural activity 2017-11-07T05:00:00Z And brain metabolism—a proxy for neuronal activity—increased in several regions of the brain. Experimental nerve-stimulation therapy partially revives man in long-term vegetative state—but experts urge caution 2017-09-25T04:00:00Z Yamashita speculates that such connections may be more than conceptually related to neuronal synapses. How the Internet of cells has biologists buzzing 2017-09-19T04:00:00Z Each number represented an observation: a person’s response to a decision problem or their reaction to another human; other numbers quantified activity in a person’s brain or the density of their neuronal fibers. Why Our Brains Resist Truth 2017-09-19T04:00:00Z “Similar actions had similar patterns of neuronal activity, and dissimilar actions had less-similar patterns,” he explains. "Movement Maps" Found Deep Inside Brain 2017-08-30T04:00:00Z According to Miyakawa, one possibility is that the increased acidity results from higher-than-normal neuronal activity in the brains of people with these disorders. Are Some Psychiatric Disorders a pH Problem? 2017-08-28T04:00:00Z Both self-described psychics and people with schizophrenia also showed abnormal neuronal activity in several brain regions responsible for monitoring our internal representations of reality. How your mind protects you against hallucinations 2017-08-10T04:00:00Z The idea of a brain condition originating with atypical neuronal connections made logical sense from the start. Using Big Data to Hack Autism 2017-07-06T04:00:00Z This drug reduces neuronal activity, and is used to treat epilepsy and neuropathic pain. Popular stomach acid blockers linked to higher death rates 2017-07-03T04:00:00Z Also likely to undergo rapid transformation is our understanding of tumours and tumour stem cells, processes such as neuronal development, metabolic disorders and neural function. Immunology, one cell at a time 2017-07-02T04:00:00Z Textbooks tell us that early infancy offers a narrow window of opportunity during which sensory experience shapes the way neuronal circuits wire up. Can Hearing Be Restored by Making the Brain More Childlike? 2017-06-29T04:00:00Z Since all perception arises from neuronal processing in the brain, Lotto argues, we don’t experience reality directly, but rather the brain’s construal of reality. Opinion | Why our grasp of reality is fragile 2017-06-09T04:00:00Z Electrodes, sometimes referred to collectively as a “brain pacemaker,” deliver high-frequency electrical pulses that interfere with neuronal activity in the targeted brain tissue. Electric Brain Stimulation Offers Binge-Eating Clue 2017-05-31T04:00:00Z “His neuronal pathways, the bridges of connection in his mind, were rickety and collapsing,” Farah writes. Electroshock “was the storm that covered them with floodwaters.” The same brain disease battering the NFL may have killed Ernest Hemingway 2017-04-28T04:00:00Z “It’s one sensory cell type and one neuronal cell type, and it’s possible to do local delivery through the eardrum.” High-Tech Hope for the Hard of Hearing 2017-03-27T04:00:00Z Critically, spatial and non-spatial representations are produced by the same neuronal population, suggesting a common circuit mechanism for encoding fundamentally different kinds of information across tasks. Mapping of a non-spatial dimension by the hippocampal–entorhinal circuit : Nature : Nature Research 2017-03-28T04:00:00Z To quantify the similarity of two sets of neuronal ensemble response patterns, we calculated the Mahalanobis distances between the two sets of population activity vectors21. Neural ensemble dynamics underlying a long-term associative memory : Nature : Nature Research 2017-03-21T04:00:00Z Some of the tone-specific neurons in the auditory task were also place-specific neurons in the foraging task, suggesting that a common neuronal network supports both types of information map. Neuroscience: Auditory landscape on the cognitive map : Nature : Nature Research 2017-03-28T04:00:00Z Deviations from this pattern, such as the formation of a neuronal precursor cell in part of the V5 cell lineage, hinted that each subprogram was also controlled by a specific genetic module. In Retrospect: Forty years of cellular clues from worms : Nature : Nature Research 2017-03-28T04:00:00Z What’s more, learning the method of loci appears to reshape neuronal networks in people’s brains, researchers reported recently in the journal Neuron. Using a 2,500-year-old method, you, too, can become a memory athlete 2017-03-17T04:00:00Z Bats also have a kind of neuronal compass that enables them to orient themselves as they fly. Sat-nav neurons tell bats where to go 2017-01-11T05:00:00Z In the study, published in the journal Cell, the scientists used a technique called optogenetics to pinpoint and eventually take control of the neuronal circuits involved in predation. Scientists use light to trigger Walking Dead-style killer instinct in mice 2017-01-12T05:00:00Z This attention might be a general prerequisite for forming a neuronal map. Neuroscience: Auditory landscape on the cognitive map : Nature : Nature Research 2017-03-28T04:00:00Z C. elegans was the first animal to be completely described at the cellular level in terms of its anatomy, development and neuronal connections, and also the first to have its genome sequenced17. In Retrospect: Forty years of cellular clues from worms : Nature : Nature Research 2017-03-28T04:00:00Z Rather than loss of restraint, it is a neuronal response, the Francis Crick Institute team says. Alcohol flips brain into hungry mode - BBC News 2017-01-10T05:00:00Z By contrast, in progressive MS, the blood–brain barrier remains intact, confining the inflammation to the brain, which fuels atrophy and neuronal loss. Therapies: Progressive steps : Nature : Nature Research 2016-11-29T05:00:00Z The so-called neuronal vulnerability hypothesis states that neurodegenerative diseases spread in an organism: concomitantly, aggregation of the amyloid protein is a cellular stress that is transferred from cell to cell. The activities of amyloids from a structural perspective : Nature : Nature Research 2016-11-08T05:00:00Z Alternatively, neuronal activity might track progression through the tonal series from the beginning of the trial to the reward. Neuroscience: Auditory landscape on the cognitive map : Nature : Nature Research 2017-03-28T04:00:00Z For example, the unc-86 gene was found to have a role in mother–daughter identity in neuronal lineages and provided hints about how daughter cells become different from their mother cells5. In Retrospect: Forty years of cellular clues from worms : Nature : Nature Research 2017-03-28T04:00:00Z Owing to the peculiar architecture of neurons, it is a challenge for these cells to alter local gene expression at the synapse in response to neuronal input or changes in the synaptic environment. Decoding ALS: from genes to mechanism : Nature : Nature Research 2016-11-08T05:00:00Z Together with a reduction in amyloid-β to halt disease progression, restoring cognition and brain health will probably need therapeutic drugs that regulate circuit activity and stimulate neuronal communication to improve the function of long-range networks. The road to restoring neural circuits for the treatment of Alzheimer's disease : Nature : Nature Research 2016-11-08T05:00:00Z Most current pattern-model theories go back to the idea that DBS breaks up the unhealthy rhythms in the motor circuitry by introducing irregular patterns of neuronal activity in the basal ganglia. Electrotherapy: Shock value : Nature : Nature Research 2016-10-25T04:00:00Z However, others5, 6 suggest that these neuronal ensembles might instead contribute in a more general way to the organization of information. Neuroscience: Auditory landscape on the cognitive map : Nature : Nature Research 2017-03-28T04:00:00Z The problem, he pointed out, was that neuronal thresholds, which affect what neurons compute, are constantly changing. Cybernetics: A mathematician of mind : Nature : Nature Research 2016-10-04T04:00:00Z This molecule helps cells called glia wrap the wirelike neuronal projections known as axons in layers of fatty insulation, or myelin. Stevens spent hours in the lab trying to model the process in a dish. This woman may know a secret to saving the brain’s synapses 2016-08-18T04:00:00Z This specialized morphology necessitates highly coordinated intracellular functions, however, AD disrupts processes that maintain neuronal health and support circuit function. The road to restoring neural circuits for the treatment of Alzheimer's disease : Nature : Nature Research 2016-11-08T05:00:00Z In response, the mice’s neuronal activity patterns shifted, leaving cells in the brain’s pacemaker region pulsing irregularly. Bright light accelerates ageing in mice 2016-07-13T04:00:00Z If neuronal activity does truly represent a map of frequency space, each tone-specific neuron would fire twice because the same frequency would be played on either side of the arc. Neuroscience: Auditory landscape on the cognitive map : Nature : Nature Research 2017-03-28T04:00:00Z These tryptophan metabolites are thought to affect neuronal signalling in the gut and brain51. Microbiome-wide association studies link dynamic microbial consortia to disease : Nature : Nature Publishing Group 2016-07-05T04:00:00Z In mice lacking a receptor for this protein, maturation of neuronal connections was delayed. This woman may know a secret to saving the brain’s synapses 2016-08-18T04:00:00Z In AD, each of these cell types undergoes changes that probably affect neuronal activity, a topic that is thoroughly covered elsewhere9. The road to restoring neural circuits for the treatment of Alzheimer's disease : Nature : Nature Research 2016-11-08T05:00:00Z The distinction between organic and emotional injury can be very blurry; trauma changes neuronal patterns, and therapy can alter a brain that has been physically damaged. What If PTSD Is More Physical Than Psychological? 2016-06-10T04:00:00Z Future studies that extend this work to other species and identify the conditions that promote sequential firing within neuronal ensembles will help to clarify how these hippocampal representations organize information and support memory formation. Neuroscience: Auditory landscape on the cognitive map : Nature : Nature Research 2017-03-28T04:00:00Z The two reports also showed that Zika virus infected and damaged neuronal stem cells harvested from mice and humans. Zika causes microcephaly in mice 2016-05-11T04:00:00Z But if dreams are defined as “bits of ‘neuronal playback’ in certain brain areas during sleep,” he said, “I’ll bet that lizards dream.” Lizards, Too, May Sleep in Stages 2016-04-28T04:00:00Z The neuronal basis for keeping the aggression of fighting fish in check is elucidated. Social conflict resolution regulated by two dorsal habenular subregions in zebrafish | Science 2016-03-31T04:00:00Z Stevens was trying to identify the proteins that recognized and eliminated neuronal synapses during visual development. Madness Runs in the Family 2016-03-28T04:00:00Z More chemical energy would mean more neuronal growth and repair, and more and better-functioning neurons in the prefrontal cortex would mean better control over the hyperactive amygdala. Meet the scientist who is hot-wiring the brain to treat depression 2016-03-03T05:00:00Z The model is built, in part, from his previous, smaller models of local neuronal circuits that show how neurons in a group fire in time. Neural modelling: Abstractions of the mind : Nature : Nature Publishing Group 2016-03-01T05:00:00Z “Contagious yawning recruits different neuronal networks involved in empathic processing, including the inferior frontal gyrus and other mirror neuron areas.” Why is yawning more contagious among women than men? 2016-02-08T05:00:00Z The neuronal basis for keeping the aggression of fighting fish in check is elucidated. Social conflict resolution regulated by two dorsal habenular subregions in zebrafish | Science 2016-03-31T04:00:00Z Perhaps C4A, like the other immunological factors that Stevens had identified in synapse pruning, marks neuronal synapses destined to be eliminated during normal brain development. Madness Runs in the Family 2016-03-28T04:00:00Z Previous studies have shown that effective trauma therapies can help the brain construct neuronal bypasses around the scarred areas of a traumatized brain. What Does a Parrot Know About PTSD? 2016-01-28T05:00:00Z These Hodgkin–Huxley equations are “beautiful and inspirational”, says neurobiologist Anthony Zador of Cold Spring Harbor Laboratory in New York, adding that they have allowed many scientists to make predictions about how neuronal excitability works. Neural modelling: Abstractions of the mind : Nature : Nature Publishing Group 2016-03-01T05:00:00Z Instead, it connects neuronal patterns with actions or mental states. Those 'mind-reading' EEG headsets definitely can't read your thoughts 2016-01-12T05:00:00Z In its wake, neuronal activity is temporarily depressed. Feature: Will antibodies finally put an end to migraines? 2016-01-07T05:00:00Z Subluxations are an example of physical nerve stress that affects neuronal control. Surprise: Chiropractors Can Treat These 5 Conditions 2015-11-30T05:00:00Z Higher-resolution scanners would permit researchers to look at small, functional groups of neurons, such as the neuronal columns of which brain cortexes are composed. The observer corps 2015-11-12T05:00:00Z “Through our neuronal studies, we saw how voter sympathy levels, approach/withdraw and voting intention variables were shifting.” Neuropolitics, Where Campaigns Try to Read Your Mind 2015-11-03T05:00:00Z They saw that when male prairie voles interacted with their special lady vole, neuronal activity in the nucleus accumbens jumped 20% compared with when they interacted with a random female. This is your brain on love (if you’re a prairie vole) 2015-10-22T04:00:00Z "Electrodes are made of hard material and they tend to damage neuronal cells," she said. 'Digital skin' activates brain cells - BBC News 2015-10-15T04:00:00Z Again, the gene led to neuronal mayhem, and the animals had muscular problems similar to what’s seen in ALS patients. Is an ancient virus responsible for some cases of Lou Gehrig’s disease? 2015-09-30T04:00:00Z It’s often not possible to directly correlate any sort of actual neuronal properties with the models. How Does a Gymnast--Or Even a Fitness Walker--Keep From Falling? 2015-08-29T04:00:00Z Increased amounts of one of them, RanGAP, which helps shuttle molecules through the nuclear pore, completely prevented neuronal degradation in the flies, the group reports in Nature this week. Plugged pores may cause dementia, other neurological diseases 2015-08-26T04:00:00Z Of course, the chemical and neuronal processes going on in your hungry brain are complex and vary from one person to another, Currie says. You Asked: Why Do I Get Hangry? 2015-08-26T04:00:00Z "Gray matter contains most of the brain's neuronal cells," Pollak said. Poverty May Hinder Kids' Brain Development, Study Says 2015-07-20T04:00:00Z Using a technique known as electroporation to insert an HERV-K gene into the brains of embryonic mice, the researchers showed similar neuronal damage. Is an ancient virus responsible for some cases of Lou Gehrig’s disease? 2015-09-30T04:00:00Z This would mean reducing the scope of his research questions to levels still valuable for understanding general principles of neuronal action, but no longer directly translatable to human investigations. Challenging times 2015-05-12T04:00:00Z In response to brain injury, the microglia release a virtual symphony of chemical mediators that orchestrate the destruction of bacterial invaders, the elimination of damaged neuronal tissue and the initiation of the repair process. Is Depression Ever Just Depression? 2015-05-12T04:00:00Z That approach reflects a shift away from linking such illnesses to chemical imbalances in the brain, instead tracing them to miswiring and misfiring in neuronal circuits. Scientists can manipulate a mouse’s brain circuitry 2015-05-04T04:00:00Z That approach reflects a shift away from linking such illnesses to "chemical imbalances" in the brain, instead tracing them to miswiring and misfiring in neuronal circuits. Obama's BRAIN Initiative yields first study results 2015-04-30T04:00:00Z “These activities may also increase cognitive reserve, maintain neuronal function, stimulate neural growth, and recruit alternate neural pathways to maintain cognitive function.” The Health Perks of Arts and Crafts For Adults 2015-04-08T04:00:00Z Other studies have shown heightened brain activity when people witness money being destroyed, with the degree of neuronal excitement increasing in lockstep with the value of the currency. 7 Ways Your Mind Messes With Your Money 2015-04-07T04:00:00Z An ambitious plan is afoot to build the world’s largest public catalogue of neuronal structures. Neuron encyclopaedia fires up to reveal brain secrets 2015-03-30T04:00:00Z So, by using the right amount of this designer virus, the researchers could selectively kill glioblastoma cells in culture without affecting normal neuronal cells. 60 Minutes Covers Duke's Polio Virus Clinical Trial Against Glioblastoma 2015-03-30T04:00:00Z Clark was deeply impressed by how localized neuronal responses were. Zap Your Brain 2015-03-30T04:00:00Z In the mammalian brain, the “defensive” and “reproductive” neuronal pathways run in parallel. Common Parasite Could Manipulate Our Behavior 2015-03-26T04:00:00Z It's thought that delta-catenin might help guide nerve cells to their proper positions in the developing brain, as part of a process called neuronal migration. Scientists Spot Gene Tied to Severe Autism in Girls 2015-03-25T04:00:00Z In recent decades, scientists have shown that the brain is a “plastic” organ that can grow neuronal connections, but this capacity diminishes with age. An Artist with Amnesia 2015-03-23T04:00:00Z Now, a study in mice points to a less invasive way to massage neuronal activity, by injecting metal nanoparticles into the brain and controlling them with magnetic fields. Magnetic 'rust' controls brain activity 2015-03-12T04:00:00Z These neuronal receptors are thought to be involved in interoception, pain sensing, mood and consciousness. What It's Like to Get High on Salvia, According to Science 2015-03-01T05:00:00Z Genetic variants associated with the condition seemed to be enriched within evolutionarily conserved regulatory elements that control immune pathways, but not in neuronal pathways, providing fresh entry points for treatment. Epigenomics: Roadmap for regulation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Children with mutations of the CTNND2 gene may end up with intellectual disorders like cri-du-chat because their genetic defect hampers proper neuronal migration during the early development of the nervous system, the NIH indicates. Scientists Spot Gene Tied to Severe Autism in Girls 2015-03-25T04:00:00Z Models derived from human pluripotent stem cells that accurately recapitulate neural development in vitro and allow for the generation of specific neuronal subtypes are of major interest to the stem cell and biomedical community. Dissecting neural differentiation regulatory networks through epigenetic footprinting : Nature : Nature Publishing Group 2014-12-23T05:00:00Z The conservation of neuronal and immune regulatory circuitry between mouse and human suggests that CK-p25 mice may offer a powerful model for studying the gene-regulatory and cognitive effects of such interventions. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease : Nature : Nature Publishing Group 2015-02-17T05:00:00Z A brain becomes a mind by coordinating “neuronal assemblies,” which work in harmony, gaining efficiency and stability as we emerge from adolescence. Are new technologies an existential threat to humans? 2015-02-13T05:00:00Z Compared with children born at term, the premature children's neuronal tracts were organized less efficiently, often taking a more meandering path. Neuroscience: The brain, interrupted 2015-02-02T05:00:00Z As you stare at the face, the neuronal mechanisms supporting its perception undergo a process of recalibration. The Face Is An Entryway to The Self 2015-01-26T05:00:00Z This in turn might serve as a mechanism to restrict their binding space in order to ensure proper neuronal and glial differentiation capacity. Dissecting neural differentiation regulatory networks through epigenetic footprinting : Nature : Nature Publishing Group 2014-12-23T05:00:00Z As I said elsewhere, I think there's more to it than just the neuronal connections, though I think this work will help produce part of the picture. Sebastian Seung’s Quest to Map the Human Brain 2015-01-08T05:00:00Z He said the landscape of the brain is more than just a series of neuronal highways marked by synaptic exits and entrances. Brainstormers: Obama’s big research push kicks off with a meeting of the minds 2015-01-02T05:00:00Z In other words, there’s a vicious cycle of oxidative stress, inflammation and neuronal death. Another Strike Against Trans Fats: They're Bad For The Brain, Study Finds 2014-11-19T05:00:00Z Another approach would interfere with the neuronal firing activity to determine whether this perturbation would affect the patient's experience of faces. The Face Is An Entryway to The Self 2015-01-26T05:00:00Z These gamma waves improve the “synchronization” of your neuronal activity, which bolsters recall and memory, Berk says. You Asked: Does Laughing Have Real Health Benefits? 2014-11-19T05:00:00Z This is also one of the reasons we process physical pain in the exact same neuronal regions we process social pain—the systems are strongly coupled. Neuroscientists Say They Discover ESP -- But Is That A Good Thing? 2014-11-07T05:00:00Z Specific patterns of neuronal activity encode her desire to perform different movements, such as swinging the arm to the left or clasping the fingers around a cup. What Is It Like to Control a Robotic Arm with a Brain Implant? 2014-11-03T05:00:00Z As he inserted an electrode through layer after layer of a rat’s brain tissue, an attached speaker emitted intermittent pops of neuronal noise. Mental Leaps Cued by Memory’s Ripples 2014-10-30T04:00:00Z Charlotte has found that, compared with a sham treatment, tDCS seems to speed up recovery, probably because of the effect that tiny electric currents have on neuronal connections inside the brain. Unexpected ways to wake up your brain 2014-10-29T04:00:00Z For we are always in need of neuronal space, and a single unconnected mind like yours would be of great value to our network. Dumpster diving : Nature : Nature Publishing Group 2014-10-28T04:00:00Z "He has done much more than discovering neuronal mechanisms in the brain: he has discovered cognitive mechanisms that explain how human beings and other animals navigate," she said. Nobel Prize for medicine goes to discoverers of brain’s 'inner GPS' 2014-10-07T04:00:00Z I asked Desimone how the conductor of the neuronal chorus—in this case, the inferior frontal junction—knows when a particular stimulus should be attended to. The Anatomy of Attention 2014-10-01T04:00:00Z It is also thought to mediate some age-related effects on the brain, in part by activation of another protein that is involved in neuronal growth and long-term memory. Can transfusions of young blood help cure Alzheimer’s in older people? The authors speculated that lithium might protect the brain, perhaps promoting neuronal growth. Should We All Take a Bit of Lithium? 2014-09-13T04:00:00Z What’s more, our bodies simply couldn’t afford to maintain so much idle neuronal tissue since the brain is an exceedingly expensive organ to own and operate—at least in terms of energy needs. I Don't Love Lucy: New Movie, Bad Science 2014-07-28T04:00:00Z Taking a different tack Companies are now diversifying their approaches and targeting the neuronal protein tau, for example, which, together with amyloid, defines Alzheimer’s. Why Alzheimer's Drugs Keep Failing 2014-07-14T04:00:00Z This reduces the polarization of the cell and promotes neuronal firing. Neurobiology: Unrestrained excitement : Nature : Nature Publishing Group 2014-07-08T04:00:00Z "Both of these neuronal processes," he says, "serve to ‘mask’ the flower scent." Your car might be screwing with pollination 2014-06-26T04:00:00Z Spears's distortion approximates the outcome of our neuronal processes when we view someone in person. 5 Illusions Reveal How Portraits Can Lie 2014-06-20T04:00:00Z This hypothesis implies that ctenophores, despite being active predators, underwent massive loss of neuronal and signalling toolkits and then replaced them with novel neurogenic and signalling molecules and receptors. The ctenophore genome and the evolutionary origins of neural systems : Nature : Nature Publishing Group 2014-05-20T04:00:00Z Most experts also agree that hiccups involve a neuronal circuit starting with the phrenic and vagus nerves. The hiccup remains a mystery, though there are many theories about its causes and cures Neurotransmitters typically act across synapses — the spaces between the neurons that form a neuronal circuit. Neurobiology: Unrestrained excitement : Nature : Nature Publishing Group 2014-07-08T04:00:00Z To accomplish these ambitious goals, the project will model many details of neuronal typology, morphology, electrophysiology, and connectivity. Which AI Model Is The Right One? 2014-05-28T04:00:00Z “It’s about specific neuronal elements in the circuit, and looking at these might be more meaningful for better treatments.” Depressed mice have excitable neurons 2014-05-27T04:00:00Z Whenever a stimulus is consciously perceived, its neuronal footprint—a particular type of brain activity—shows up in many parts of the cerebral cortex. Consciousness Might Emerge from a Data Broadcast 2014-05-23T04:00:00Z He postulated that the brain is not like a computer, hard-wired for certain capacities, but rather is sculpted over time through experiences that strengthen neuronal connections. Gerald M. Edelman, Nobel Prize-winning scientist, dies They found that even limited restraint of neuronal firing in a region of the motor cortex markedly reduced the number of seizure events in a rat model of cortical epilepsy. Neurobiology: Unrestrained excitement : Nature : Nature Publishing Group 2014-07-08T04:00:00Z Dr. Edelman believed that when something happened in the world — something encountered by one of our senses — some neuronal groups responded and were strengthened by a series of biological processes. Gerald M. Edelman, Nobel Laureate and ‘Neural Darwinist,’ Dies at 84 2014-05-22T04:00:00Z Optogenetic technology allows for in vivo control of neuronal firing with millisecond precision using light delivered at a distance from the target and, thus, avoids extensive electrode-related tissue damage. [Research Article] Neuronal Activity Promotes Oligodendrogenesis and Adaptive Myelination in the Mammalian Brain 2014-05-01T18:26:14.316Z As it reaches anterior regions of cortex, the signals increase in amplitude, prompting Dehaene to call it a neuronal avalanche. Consciousness Might Emerge from a Data Broadcast 2014-05-23T04:00:00Z As we learn and experience the world around us, our brains are remodeling neuronal pathways. [Perspective] A New Wrap for Neuronal Activity? 2014-05-01T18:25:58.611Z Seizures share a common feature: a breakdown in the mechanisms that normally constrain neuronal activation, or firing. Neurobiology: Unrestrained excitement : Nature : Nature Publishing Group 2014-07-08T04:00:00Z Much of its study of the brain is based on the theory of neuronal group selection and computer simulations of nervous systems. Gerald M. Edelman, Nobel Laureate and ‘Neural Darwinist,’ Dies at 84 2014-05-22T04:00:00Z Animals were evaluated at various time points to examine the effects of neuronal activity on myelin-forming cells and myelin microstructure, as well as the functional consequences of neuronal activity–regulated myelin changes. [Research Article] Neuronal Activity Promotes Oligodendrogenesis and Adaptive Myelination in the Mammalian Brain 2014-05-01T18:26:14.316Z We presented two temporally and spatially overlapping streams of objects, faces versus houses, and used magnetoencephalography and functional magnetic resonance imaging to separate neuronal responses to attended and unattended objects. [Report] Neural Mechanisms of Object-Based Attention 2014-04-29T14:56:53.249Z In a neuronal circuit, information is transmitted through neurons in the form of an action potential, which is the electric potential difference between the inside and the outside of a neuron. [Perspective] Silencing Neurons with Light 2014-04-29T14:56:15.053Z “So on the one hand you have this neuronal effect, and on the other you have a persistence of the inflammatory milieu because these neurons are activating the glia continuously,” says Vezzani. Neurobiology: Unrestrained excitement : Nature : Nature Publishing Group 2014-07-08T04:00:00Z Within the dense thicket of nerve cells in the brain, known as neurons, are a vast array of neuronal groups. Gerald M. Edelman, Nobel Laureate and ‘Neural Darwinist,’ Dies at 84 2014-05-22T04:00:00Z We use in vivo optogenetic techniques in awake, behaving mice to provide direct evidence that neuronal activity regulates changes in myelin-forming cells within an active circuit. [Research Article] Neuronal Activity Promotes Oligodendrogenesis and Adaptive Myelination in the Mammalian Brain 2014-05-01T18:26:14.316Z Because of the “close proximity” of the doses, Knapp says, “It is still important to continue to investigate how selective the actions of ezogabine are on the neuronal mechanisms that control alcohol consumption.” Potential New Treatment for Alcoholism: Epilepsy Drug Ezogabine 2014-04-17T22:40:00Z Rotenone may also interfere with the normal neuronal clearance of damaged or degraded proteins. Parkinson's Disease and Pesticides: What's the Connection? 2014-04-08T11:00:00Z There is evidence that penetration of this compromised barrier by molecules such as the protein albumin can exacerbate both neuronal hyperexcitability and inflammation. Neurobiology: Unrestrained excitement : Nature : Nature Publishing Group 2014-07-08T04:00:00Z The mouse’s neuronal connections also vary widely in strength. Researchers report that they have created a diagram of a mouse’s brain 2014-04-07T18:00:18Z We further show that this neuronal activity–regulated oligodendrogenesis and myelination is associated with improved motor function of the corresponding limb. [Research Article] Neuronal Activity Promotes Oligodendrogenesis and Adaptive Myelination in the Mammalian Brain 2014-05-01T18:26:14.316Z The researchers stimulated more than 1,000 different neuronal pathways in nearly 38,000 Drosophila flies, and recorded how the flies responded. Neurobiology: Brain map reveals behaviour links 2014-04-04T22:50:05.525Z Death of pericytes in rigor will produce a long-lasting decrease of cerebral blood flow, and reduce the ability of the microvasculature to increase blood flow in response to neuronal activity. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z “But what comes first — the neuronal defect or the astrocyte defect — is the issue.” Neurobiology: Unrestrained excitement : Nature : Nature Publishing Group 2014-07-08T04:00:00Z Thus, pericytes surrounding capillaries initiate changes in local blood flow in response to neuronal activity, and thereby provide a sensitive control mechanism to match neuronal activity and blood supply throughout the brain. Vascular biology: Brain vessels squeezed to death 2014-04-04T18:23:16.270Z Progress is being made in reprogramming such cells into relevant neuronal and glial cell types, although questions remain over the cell types most involved in various psychiatric disorders. Perspective: Revealing molecular secrets 2014-04-02T17:21:26.216Z “It may be that neuronal function is perfectly fine under most circumstances, but if a body of neurons gets stressed in a certain way that can tip a person over,” says Sullivan. Genetics: Unravelling complexity 2014-04-02T17:21:00.997Z We have now characterized the responses of pericytes in the neocortex and cerebellum to neuronal activity and ischaemia. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z The neuronal network underlying this executive function, classically attributed to the rostral cingulate zone, is poorly characterized in humans, owing to the limited number of direct neurophysiological data. [Report] Action Monitoring and Medial Frontal Cortex: Leading Role of Supplementary Motor Area 2014-02-20T19:26:03.031Z To determine the role of pericytes in vasodilation, Hall et al. first investigated the molecular signals regulating capillary dilation induced by neuronal activity in slices of rodent cerebellum. Vascular biology: Brain vessels squeezed to death 2014-04-04T18:23:16.270Z My research involves work with macaques to investigate the neuronal mechanisms that underlie visual perception and attention. Science at the sharp end of oppressive politics 2014-02-18T15:50:12.176Z Evidence for neuronal dysfunction and the frequent development of epilepsy strongly support increased excitatory and decreased inhibitory neuronal activity in ASD. [Perspective] Could Autism Be Treated Prenatally? 2014-02-06T19:26:03.061Z Understanding what initiates the blood-flow increase in response to neuronal activity is crucial for understanding both how information processing is powered and how functional imaging signals are generated. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z In the mammalian central nervous system, this approach has been used experimentally to generate new categories of neuronal cells. [Review] Development-Inspired Reprogramming of the Mammalian Central Nervous System 2014-01-30T19:25:54.261Z In response to neuronal activity, pericytes relax their grip on cerebral capillaries, causing blood-vessel dilation and increasing the oxygen supply to active neurons. Vascular biology: Brain vessels squeezed to death 2014-04-04T18:23:16.270Z At least one drug under development is designed to combat the disorder by stimulating neuronal growth. Take Care of Your Brain and Your Friendships 2014-01-07T23:15:04.038Z Their constitutive proteins, genes, synapses, cells and neuronal circuits are as sophisticated, variegated and specialized as anything seen in the human brain. Is Consciousness Universal? 2014-01-01T05:45:00.400Z Death of pericytes in rigor will produce a long-lasting decrease of cerebral blood flow, and reduce the ability of the microvasculature to increase blood flow in response to neuronal activity. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z Future ability to reprogram postmitotic neurons in the adult brain will be important for the growth of this field and likely influence the way we think about neuronal stability, regeneration, and function. [Review] Development-Inspired Reprogramming of the Mammalian Central Nervous System 2014-01-30T19:25:54.261Z For example, is dilation of larger arterioles, induced by neuronal activity, sufficient to cause an increase in blood flow in smaller capillaries, or is vasodilation initiated at capillaries? Vascular biology: Brain vessels squeezed to death 2014-04-04T18:23:16.270Z The control of motor behavior in animals and humans requires constant adaptation of neuronal networks to signals of various types and strengths. [Report] MicroRNA-128 Governs Neuronal Excitability and Motor Behavior in Mice 2013-12-05T18:57:37.892Z In developing mouse somatosensory cortex, endogenous Btbd3 translocated to the cell nucleus in response to neuronal activity and oriented primary dendrites toward active axons in the barrel hollow. [Report] BTBD3 Controls Dendrite Orientation Toward Active Axons in Mammalian Neocortex 2013-12-04T22:56:58.093Z We demonstrate that neuronal activity and the neurotransmitter glutamate evoke the release of messengers that dilate capillaries by actively relaxing pericytes. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z The approaches also allow for new ways to study human neuronal development, a process that cannot be studied in vivo.Advances: [Review] Development-Inspired Reprogramming of the Mammalian Central Nervous System 2014-01-30T19:25:54.261Z When a major vessel that supplies blood to the brain becomes obstructed, capillary blood flow is interrupted, and this may deplete the brain's oxygen supply, causing rapid loss of neuronal function, cell death and stroke. Vascular biology: Brain vessels squeezed to death 2014-04-04T18:23:16.270Z We recorded medial temporal lobe neuronal activity as epilepsy patients performed a hybrid spatial and episodic memory task. [Report] Neural Activity in Human Hippocampal Formation Reveals the Spatial Context of Retrieved Memories 2013-12-04T22:56:55.929Z This mechanism enables the construction of polarized neuronal shapes for integration into neural circuits with the required finescale architecture to process subtle activity patterns, a property underlying complex behavior. [Report] BTBD3 Controls Dendrite Orientation Toward Active Axons in Mammalian Neocortex 2013-12-04T22:56:58.093Z We demonstrate that, unexpectedly, pericytes are the first vascular elements to dilate during neuronal activity, making them the initiators of functional imaging signals. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z These protocols have provided a renewable source of neuronal cells for high-throughput studies, which is particularly useful when source tissue is rare or unavailable. [Review] Development-Inspired Reprogramming of the Mammalian Central Nervous System 2014-01-30T19:25:54.261Z Less glutamate leads to “a lower seizure risk and a better environment for neuronal recovery and repair.” Do Low Carbohydrate Diets Make You Dumber? 2013-11-12T16:54:00Z The exercise enhances her muscle power as well as rewiring some of her disabled neuronal pathways. Paralyzed Woman Walks Again, with the Aid of a Robot 2013-09-24T21:45:08.840Z Along the way, the team discovered several new types of neurons, and generated a neuronal wiring map of unprecedented scale and complexity. The Neuroscience Revolution Will Be Crowdsourced 2013-09-12T14:16:25.173Z Both of these will contribute to ongoing neuronal damage, highlighting the potential importance of preventing pericyte death as a therapeutic strategy after stroke, particularly in the penumbra of an affected region. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z These provocative results may foster the development of strategies for neuronal replacement that rely on “code-switching” of neuronal identity on the spot.Outlook: [Review] Development-Inspired Reprogramming of the Mammalian Central Nervous System 2014-01-30T19:25:54.261Z Ensheath synapses, regulate neuronal excitability and synaptic transmission.Respond to injury by secreting extracellular matrix proteins.Implicated in neurogenesis, cell migration, and many neurological and psychiatric disorders. Neuroscience: Map the other brain 2013-09-05T20:20:29.767Z The modern stylus is the microelectrode, and with it we probe our neuronal wax. Mnemodystopia: A Little Context 2013-08-26T16:45:03.317Z Amid the anatomical, electrophysiological, and biochemical diversity of nerve cells, the field is struggling to devise simple and clear criteria for neuronal classification. [Perspective] Mapping Neuronal Diversity One Cell at a Time 2013-08-15T17:56:21.057Z Thus, capillary dilation is predicted to generate 84% of the steady state increase in blood flow evoked by prolonged neuronal activity. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z The research is changing how scientists think about regeneration of lost neurons and modeling of neuronal function in the central nervous system. [Review] Development-Inspired Reprogramming of the Mammalian Central Nervous System 2014-01-30T19:25:54.261Z These reside outside the neuronal 'connectome' and operate beyond the reach of tools designed to probe electrical signalling in neurons. Neuroscience: Map the other brain 2013-09-05T20:20:29.767Z Different brain activity accompanies a hand scribbling on paper or typing, with the former invoking neuronal circuits of movement and spatial processing. How We Learn 2013-08-15T12:15:00.740Z Such a classification method would provide new insights into CNS organization, development, and function, and might reveal unexpected relationships between neuronal subtypes. [Perspective] Mapping Neuronal Diversity One Cell at a Time 2013-08-15T17:56:21.057Z Death of pericytes in rigor will produce a long-lasting decrease of cerebral blood flow, and reduce the ability of the microvasculature to increase blood flow in response to neuronal activity. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z These pulses are one of the neuronal features that are thought to underpin consciousness in humans, especially when they help to "link" information from different parts of the brain. Near-death experiences 'explained' 2013-08-13T00:04:28Z “So they are two sides of the same coin, and the prospect of deploying them together in an experiment would allow wholly optical closed-loop control of neuronal circuits.” Lighting up the brain with ArcLight 2013-08-12T13:45:03.067Z |
| 随便看 |
英语例句辞典收录了117811条英语例句在线翻译词条，基本涵盖了全部常用单词及词组的例句翻译及用法，是英语学习的有利工具。