单词 | myosin |
例句 | Within each block, are hundreds of myosin filaments. Researcher helps solve 60-year mystery inside heart 2023-11-14T05:00:00Z The arrangement of the myosin molecules depends on their position in the filament. Breakthrough discovery sheds light on heart and muscle health 2023-11-01T04:00:00Z For example, where the needle poke destroys muscle, these cells make a lot of myosin protein, which helps muscles contract. Cells with extra genomes may help tissues respond to injuries—and species survive cataclysms 2023-08-23T04:00:00Z The cells produce specific proteins—actin and myosin—that cause muscles to contract and relax like rubber bands at different speeds. How to Keep Muscles Strong as You Age 2023-07-02T04:00:00Z While they differ in many regards, they all use actin sliding against myosin to create muscle contraction and relaxation. Fundamentals of Biology 2015-01-01T00:00:00Z The study titled "Cryo-EM structure of the human cardiac myosin filament" was published online in the journal Nature earlier this month. Researcher helps solve 60-year mystery inside heart 2023-11-14T05:00:00Z Titin chains intertwine with myosin, acting as a scaffold for its assembly and probably orchestrating a length-depending activation of the sarcomere. Breakthrough discovery sheds light on heart and muscle health 2023-11-01T04:00:00Z The striated appearance of skeletal muscle tissue is a result of repeating bands of the proteins actin and myosin that occur along the length of myofibrils. Concepts of Biology 2013-04-25T00:00:00Z These calcium ions activate another type of protein filament called myosin that induces the cell to move. How cancer cells move and metastasize is influenced by the fluids surrounding them 2023-01-10T05:00:00Z In addition to the collection of organelles typical of eukaryotic cells, each muscle fiber contains myofibrils, which, in turn, consist of arrangements of protein filaments called actin and myosin. Biology for AP Courses 2022-06-09T00:00:00Z The triad surrounds the cylindrical structure called a myofibril, which contains actin and myosin. Anatomy and Physiology 2013-06-19T00:00:00Z The latter can form links between the filaments, whereas myosin, the so-called motor protein interacts with the thin filament to generate force and muscle contraction. Breakthrough discovery sheds light on heart and muscle health 2023-11-01T04:00:00Z Contraction of the muscle occurs by the combined action of myosin and actin fibers sliding past each other when the myosin heads bind to the actin fiber, bend, disengage, and then repeat the process. Concepts of Biology 2013-04-25T00:00:00Z The way in which the actin and myosin are arranged in these cells is also animal-like. Marine Microbe Performs Animal Trick 2020-03-08T05:00:00Z The binding of myosin to actin causes the actin filaments to slide, shortening the muscle fiber. Biology for AP Courses 2022-06-09T00:00:00Z The striations are created by the organization of actin and myosin resulting in the banding pattern of myofibrils. Anatomy and Physiology 2013-06-19T00:00:00Z These proteins, in turn, facilitate the assembly of thick, cable-like, oriented arrays of actin–myosin filaments called stress fibres. Tension in tumour cells keeps metabolism high 2020-02-11T05:00:00Z The myosin head then releases its actin filament, relaxes, and then repeats the process, dragging the two filaments further along each other. Concepts of Biology 2013-04-25T00:00:00Z Latorre et al. focused on the cell cortex, a meshwork of actin filaments and myosin that forms a thin layer beneath the cell membrane. Cellular stretch reveals superelastic powers 2018-10-30T04:00:00Z Strands of tropomyosin block the binding sites and prevent actin–myosin interactions when the muscles are at rest. Biology for AP Courses 2022-06-09T00:00:00Z The number of cross-bridges formed between actin and myosin determines the amount of tension produced by a muscle. Anatomy and Physiology 2013-06-19T00:00:00Z Next, the authors manipulated levels of myosin or actin and found changes in TRIM21 positioning within the cell. Tension in tumour cells keeps metabolism high 2020-02-11T05:00:00Z The movement of the myosin head requires ATP, which provides the energy for the contraction. Concepts of Biology 2013-04-25T00:00:00Z Using this approach, Ando’s team has been able to watch the motor protein myosin V ‘walk’ along a strand of actin at the rate of up to 20 images per second6. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z ATP binding causes myosin to release actin, allowing actin and myosin to detach from each other. Biology for AP Courses 2022-06-09T00:00:00Z Ca++ also is required for the contraction of smooth muscle, although its role is different: here Ca++ activates enzymes, which in turn activate myosin heads. Anatomy and Physiology 2013-06-19T00:00:00Z To confirm that the actin and myosin were facilitating the movement, the researchers created genetically modified versions of the cells in which those proteins were inactive. Inside Wounded Flies, Fat Cells Race to the Rescue 2018-02-26T05:00:00Z A discussion of, say, the role of transcription factors or forces in myosin–actin networks in guiding development presents a communication challenge, no matter how beautifully illustrated with micrographs of stained cells. How poets and filmmakers construe complexity at the Crick Institute 2018-02-12T05:00:00Z The researchers added myosin's natural fuel, ATP, then put the mixture on a microscope slide and watched. The physics of life 2016-01-04T05:00:00Z The myosin head is then in a position for further movement, possessing potential energy, but ADP and Pi are still attached. Biology for AP Courses 2022-06-09T00:00:00Z Differences among the three muscle types include the microscopic organization of their contractile proteins—actin and myosin. Anatomy and Physiology 2013-06-19T00:00:00Z But instead, their analysis shows it was a gene that codes for myosin, a protein essential for muscle contraction. One hundred and one monarch genomes reveal surprising history of this long-distant migrant 2014-10-01T04:00:00Z Rigor occurs because when the ATP level falls, muscle cells like pericytes cannot detach their myosin heads from actin to relax. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z He and his colleagues mixed actin, a filament that forms most of the cytoskeleton of complex cells, with myosin, a molecular motor that 'walks' on actin and makes muscles contract. The physics of life 2016-01-04T05:00:00Z Pi is then released, allowing myosin to expend the stored energy as a conformational change. Biology for AP Courses 2022-06-09T00:00:00Z Tropomyosin is a protein that winds around the chains of the actin filament and covers the myosin-binding sites to prevent actin from binding to myosin. Anatomy and Physiology 2013-06-19T00:00:00Z The butterfly myosin gene resembles a myosin gene that is mutated in a mouse strain that has light instead of dark fur. One hundred and one monarch genomes reveal surprising history of this long-distant migrant 2014-10-01T04:00:00Z In rigor mortis, stiffness results from a lack of ATP molecules, which prevents myosin and actin — two proteins that interact to cause muscle contraction — from being separated from one another. Vascular biology: Brain vessels squeezed to death 2014-04-04T18:23:16.270Z The signals likely reflect stretch-induced myosin deformation, which would also enhance force in vertebrate muscles. [Report] The Molecular Trigger for High-Speed Wing Beats in a Bee 2013-09-12T17:57:14.123Z During the power stroke, the myosin head bends with the release of ADP and inorganic phosphate. Biology for AP Courses 2022-06-09T00:00:00Z Pi is then released, causing myosin to form a stronger attachment to the actin, after which the myosin head moves toward the M-line, pulling the actin along with it. Anatomy and Physiology 2013-06-19T00:00:00Z In the mouse, this myosin helps transport pigments into the hair, so Kronforst thinks the white morph's myosin may fail to transport orange pigment into the wing scales. One hundred and one monarch genomes reveal surprising history of this long-distant migrant 2014-10-01T04:00:00Z The basics of how muscle generates power remain the same - filaments of myosin tug on filaments of actin to shorten or contract the muscle. 'Muscle power truths' revealed 2013-07-09T23:56:52Z For example, Dr. Spudich said, heartbeat depends on a myosin motor that produces the contractions with every beat. Seven Scientists Win 2012 Lasker Award 2012-09-10T21:28:51Z The actin head forms a cross-bridge with myosin which initiates the power stroke. Biology for AP Courses 2022-06-09T00:00:00Z In the absence of ATP, the myosin head will not detach from actin. Anatomy and Physiology 2013-06-19T00:00:00Z PIA was prevented by inducing tolerance to α-myosin, demonstrating that immune responses to cardiac myosin are essential for this disease process. [Research Articles] Myocardial Infarction Triggers Chronic Cardiac Autoimmunity in Type 1 Diabetes 2012-06-13T18:55:13.683Z But myosin doesn't tug in one direction, as previously thought. 'Muscle power truths' revealed 2013-07-09T23:56:52Z The muscular fibres are found with the microscope to be swollen, irregular in outline, the myosin transformed into flaky, glistening masses, without evidence of the normal transverse striation. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z The myosin head forms a cross-bridge with actin which initiates the power stroke. Biology for AP Courses 2022-06-09T00:00:00Z One part of the myosin head attaches to the binding site on the actin, but the head has another binding site for ATP. Anatomy and Physiology 2013-06-19T00:00:00Z But there’s still enough myosin so that when the proteins are heated, they bond to create a gel that holds the patty together without the need for a casing. Findings: Could Liquid Nitrogen Help Build Tasty Burgers? 2011-06-06T21:30:32Z Muscle contractions in the heart are controlled by a protein called myosin heavy chain. A Change of Heart Keeps Bears Healthy While Hibernating 2011-02-09T15:11:00Z The drug, given either in intravenous or oral form, works by activating a protein called cardiac myosin. 2010-02-11T17:20:00Z During the power stroke, the myosin head bends with release of ADP and inorganic phosphate. Biology for AP Courses 2022-06-09T00:00:00Z After the power stroke, ADP is released; however, the formed cross-bridge is still in place, and actin and myosin are bound together. Anatomy and Physiology 2013-06-19T00:00:00Z In animal foods myosin in meat and vitellin, found in the yolk of the egg, and some of the proteids of the blood, are examples of globulins. Human Foods and Their Nutritive Value A well-known variety, called albumin, is found in the white of eggs and in the plasma of the blood, while the muscles contain an abundance of another variety, known as myosin. Physiology and Hygiene for Secondary Schools The drug binds to myosin and triggers it to grab on and stay attached to a long string of proteins called actin. 2010-02-11T17:20:00Z The actin head forms a cross-bridge with myosin, which initiates the power stroke. Biology for AP Courses 2022-06-09T00:00:00Z With no further ATP production possible, there is no ATP available for myosin heads to detach from the actin-binding sites, so the cross-bridges stay in place, causing the rigidity in the skeletal muscles. Anatomy and Physiology 2013-06-19T00:00:00Z Numerous kinds of protein occur in meat, but the chief varieties are myosin and muscle albumin. Woman's Institute Library of Cookery Volume 3: Soup; Meat; Poultry and Game; Fish and Shell Fish The chief proteins are: First, the albuminoids, which are represented by the albumin in eggs, the casein in milk and cheese, the myosin of muscle and the gluten of wheat. Maintaining Health Formerly Health and Efficiency One of the chief constituents of muscular fiber is myosin. A Practical Physiology To keep actin from binding to the active site on myosin, regulatory proteins block the molecular binding sites. Biology for AP Courses 2022-06-09T00:00:00Z Here, the biceps brachii contracts as sarcomeres in its muscle fibers are shortening and cross-bridges form; the myosin heads pull the actin. Anatomy and Physiology 2013-06-19T00:00:00Z The myosin, which is the most important protein and occurs in the greatest quantity, hardens after the animal has been killed and the muscles have become cold. Woman's Institute Library of Cookery Volume 3: Soup; Meat; Poultry and Game; Fish and Shell Fish As not much myosin is extracted from meat in soup making, the solid part of meat must be eaten in order to obtain the greatest nourishment. School and Home Cooking The proteids, frequently spoken of as the nitrogenous foods, are rich in one or more of the following organic substances: albumen, casein, fibrin, gelatine, myosin, gluten, and legumin. A Practical Physiology Once the tropomyosin is removed, a cross- bridge can form between actin and myosin, triggering contraction. Biology for AP Courses 2022-06-09T00:00:00Z The striation is due to the regular alternation of the contractile proteins actin and myosin, along with the structural proteins that couple the contractile proteins to connective tissues. Anatomy and Physiology 2013-06-19T00:00:00Z As examples may be quoted, myosin the chief protein of ordinary meat or muscle, ovalbumin one of the proteins of egg-white, casein belonging to milk and cheese, and gluten a protein-mixture in flour. The Home of the Blizzard Being the Story of the Australasian Antarctic Expedition, 1911-1914 Even though the meat has been cooked so as to extract its juices, there still remains practically all of the myosin, and this is a valuable constituent. School and Home Cooking The enzyme at the binding site on myosin is called ATPase. Biology for AP Courses 2022-06-09T00:00:00Z Cross-bridges can only form where thick and thin filaments overlap, allowing myosin to bind to actin. Biology for AP Courses 2022-06-09T00:00:00Z Once released, the Ca++ interacts with the shielding proteins, forcing them to move aside so that the actin-binding sites are available for attachment by myosin heads. Anatomy and Physiology 2013-06-19T00:00:00Z If actin binding sites are covered and unavailable, the myosin will remain in the high energy configuration with ATP hydrolyzed, but still attached. Biology for AP Courses 2022-06-09T00:00:00Z In muscle juice, there are two proteins,—myosin or muscle globulin and albumin. School and Home Cooking If the actin binding sites are uncovered, a cross-bridge will form; that is, the myosin head spans the distance between the actin and myosin molecules. Biology for AP Courses 2022-06-09T00:00:00Z If more cross-bridges are formed, more myosin will pull on actin, and more tension will be produced. Biology for AP Courses 2022-06-09T00:00:00Z The myosin then pulls the actin filaments toward the center, shortening the muscle fiber. Anatomy and Physiology 2013-06-19T00:00:00Z The myosin head moves toward the M line, pulling the actin along with it. Biology for AP Courses 2022-06-09T00:00:00Z Of all proteins in meat, myosin is the most important; it exists in greater quantity than the other proteins. School and Home Cooking This energy is expended as the myosin head moves through the power stroke; at the end of the power stroke, the myosin head is in a low-energy position. Biology for AP Courses 2022-06-09T00:00:00Z As a sarcomere is shortened, the zone of overlap is reduced as the thin filaments reach the H zone, which is composed of myosin tails. Biology for AP Courses 2022-06-09T00:00:00Z The contraction of a striated muscle fiber occurs as the sarcomeres, linearly arranged within myofibrils, shorten as myosin heads pull on the actin filaments. Anatomy and Physiology 2013-06-19T00:00:00Z After the power stroke, ADP is released; however, the cross-bridge formed is still in place, and actin and myosin are bound together. Biology for AP Courses 2022-06-09T00:00:00Z Why can’t actin and myosin interact in the absence of calcium? Biology for AP Courses 2022-06-09T00:00:00Z The myosin head forms a cross-bridge with actin, which initiates the power stroke. Biology for AP Courses 2022-06-09T00:00:00Z Because it is myosin heads that form cross-bridges, actin will not bind to myosin in this zone, reducing the tension produced by this myofiber. Biology for AP Courses 2022-06-09T00:00:00Z This allows the myosin heads to bind to these exposed binding sites and form cross-bridges. Anatomy and Physiology 2013-06-19T00:00:00Z The number of cross-bridges formed between actin and myosin determine the amount of tension that a muscle fiber can produce. Biology for AP Courses 2022-06-09T00:00:00Z This results in fewer myosin heads pulling on actin, and less tension is produced. Biology for AP Courses 2022-06-09T00:00:00Z In relaxed muscle, the myosin binding site on actin is blocked by . Biology for AP Courses 2022-06-09T00:00:00Z In the sliding filament model of muscle contraction, the thicker myosin filaments have cross-bridges that attach and detach to thinner actin filaments. Biology for AP Courses 2022-06-09T00:00:00Z The thin filaments are then pulled by the myosin heads to slide past the thick filaments toward the center of the sarcomere. Anatomy and Physiology 2013-06-19T00:00:00Z Below the accepted phylogeny of major groups are rows with families of genes that code for different muscle proteins, including actin and myosin. Biology for AP Courses 2022-06-09T00:00:00Z Actin and myosin are plentiful in muscle cells. Biology for AP Courses 2022-06-09T00:00:00Z When your actin and myosin filaments slide past each other, your muscles contract. Biology for AP Courses 2022-06-09T00:00:00Z When Ca2+ is released in response to the change in voltage, it binds to actin, causing actin filaments to shift position and revealing myosin binding sites for the cross-bridges. Biology for AP Courses 2022-06-09T00:00:00Z Each cycle requires energy, and the action of the myosin heads in the sarcomeres repetitively pulling on the thin filaments also requires energy, which is provided by ATP. Anatomy and Physiology 2013-06-19T00:00:00Z As long as ATP is available, it readily attaches to myosin, the cross-bridge cycle can recur, and muscle contraction can continue. Anatomy and Physiology 2013-06-19T00:00:00Z Note that each thick filament of roughly 300 myosin molecules has multiple myosin heads, and many cross-bridges form and break continuously during muscle contraction. Anatomy and Physiology 2013-06-19T00:00:00Z This length maximizes the overlap of actin-binding sites and myosin heads. Anatomy and Physiology 2013-06-19T00:00:00Z Actin is a globular contractile protein that interacts with myosin for muscle contraction. Biology for AP Courses 2022-06-09T00:00:00Z After this occurs, ATP is converted to ADP and Pi by the intrinsic ATPase activity of myosin. Anatomy and Physiology 2013-06-19T00:00:00Z Although they do not have striations and sarcomeres, smooth muscle fibers do have actin and myosin contractile proteins, and thick and thin filaments. Anatomy and Physiology 2013-06-19T00:00:00Z Some smooth muscle can also maintain contractions even as Ca++ is removed and myosin kinase is inactivated/dephosphorylated. Anatomy and Physiology 2013-06-19T00:00:00Z This can happen as a subset of cross-bridges between myosin heads and actin, called latch-bridges, keep the thick and thin filaments linked together for a prolonged period, and without the need for ATP. Anatomy and Physiology 2013-06-19T00:00:00Z The striated appearance of skeletal muscle tissue is a result of repeating bands of the proteins actin and myosin that are present along the length of myofibrils. Biology for AP Courses 2022-06-09T00:00:00Z The myosin head is now in position for further movement. Anatomy and Physiology 2013-06-19T00:00:00Z Thick filaments are composed of the protein myosin; thin filaments are composed of the protein actin. Anatomy and Physiology 2013-06-19T00:00:00Z Actin fibers, twisted chains of actin filaments, constitute a large component of muscle tissue and, along with the protein myosin, are responsible for muscle contraction. Anatomy and Physiology 2013-06-19T00:00:00Z In muscle cells, these long actin strands, called thin filaments, are “pulled” by thick filaments of the myosin protein to contract the cell. Anatomy and Physiology 2013-06-19T00:00:00Z Thick filaments are composed of the protein myosin. Biology for AP Courses 2022-06-09T00:00:00Z This energy is expended as the myosin head moves through the power stroke, and at the end of the power stroke, the myosin head is in a low-energy position. Anatomy and Physiology 2013-06-19T00:00:00Z No striations are evident because the actin and myosin filaments do not align in the cytoplasm. Anatomy and Physiology 2013-06-19T00:00:00Z Tolerance is broken because heart myosin antigens are similar to antigens on the β- Streptococcus bacteria. Anatomy and Physiology 2013-06-19T00:00:00Z The antibodies to this pathogen’s M protein cross-react with an antigenic component of heart myosin, a major contractile protein of the heart that is critical to its normal function. Anatomy and Physiology 2013-06-19T00:00:00Z |
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