| 单词 | monogenic |
| 例句 | Eukaryotic mRNAs are usually monogenic, meaning that they specify a single protein. Biology for AP Courses 2022-06-09T00:00:00Z Most of us support a future where Crispr is used to treat over 10,000 monogenic diseases that impact 75 million people every year. Gene editing like Crispr is too important to be left to scientists alone | Natalie Kofler 2019-10-22T04:00:00Z "For example, people carrying mutations giving high risk of certain diseases, and also monogenic conditions such as breast cancer mutations." Is routine genetic profiling coming closer? 2019-07-29T04:00:00Z More than 10,000 monogenic inherited disorders have been identified, affecting millions of people worldwide. Correction of a pathogenic gene mutation in human embryos : Nature : Nature Research 2017-08-01T04:00:00Z The only exceptions to what is called “common obesity” — where many genes are involved in raising the risk of obesity — occur in what is known as “monogenic” obesity. Genes can push you toward obesity, but there are things you can do to prevent that 2017-08-11T04:00:00Z The consensus is that monogenic diseases — those involving only one gene — are the low-hanging fruit of the field. Medicine: Expanding possibilities : Nature : Nature Publishing Group 2015-12-01T05:00:00Z Unfortunately, although the vast majority of genes reported as causally linked to monogenic diseases are true positives, false assignments of causality at the variant level are a substantial issue. Guidelines for investigating causality of sequence variants in human disease 2014-04-23T17:21:03.147Z A second major finding was that other genes may play an important contributing role in determining LDL levels even in monogenic FH patients. Study Casts Doubt On Value Of Genetic Testing For Familial Hypercholesterolemia 2013-02-21T23:30:24Z Each term of the series being a monogenic function of z, the series may therefore be differentiated and integrated outside these circles, and represents a monogenic function. Encyclopaedia Britannica, 11th Edition, Volume 11, Slice 3 "Frost" to "Fyzabad" 2011-08-15T02:00:28.473Z We consider a single gene as the fundamental unit for monogenic disease gene testing, for all disease models; a disease caused by de novo mutations or a disease caused by inherited dominant or recessive variants. Guidelines for investigating causality of sequence variants in human disease 2014-04-23T17:21:03.147Z Algebraic Functions.—The explanations and definitions of a monogenic function hitherto given have been framed for the most part with a view to single valued functions. Encyclopaedia Britannica, 11th Edition, Volume 11, Slice 3 "Frost" to "Fyzabad" 2011-08-15T02:00:28.473Z For presumed monogenic diseases, the availability of multiple families with very similar clinical phenotypes substantially increases power for gene discovery. Guidelines for investigating causality of sequence variants in human disease 2014-04-23T17:21:03.147Z “Cascade” screening, in which DNA tests are recommended for all relatives of patients with a clinical diagnosis of FH, should only be performed on the monogenic patients, they maintain. Study Casts Doubt On Value Of Genetic Testing For Familial Hypercholesterolemia 2013-02-21T23:30:24Z There cannot be two functions with the given perimeter values, since their difference would be a monogenic potential function with boundary value zero, which can easily be shown to be everywhere zero. Encyclopaedia Britannica, 11th Edition, Volume 11, Slice 3 "Frost" to "Fyzabad" 2011-08-15T02:00:28.473Z |
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