| 单词 | monocyte |
| 例句 | Although normally monocytes and macrophages were not known as the primary defense force against viruses, the authors found that they activated other immune cells, so-called natural killer cells, that help fight the virus. Boosting weak immune system: Scientists find an unusual weapon against virus 2023-10-17T04:00:00Z In the spleen, most of the infected cells detected were frontline immune cells -- macrophages and monocytes -- known as phagocytes whose job is to swallow up invading organisms. A lethal parasite's secret weapon: Infecting non-immune cells 2023-09-29T04:00:00Z As one of these immune cells matures, it usually goes through an intermediate stage known as a monocyte, but the yolk sac macrophages bypass this step. Three organs in one? Researchers unscramble mysterious roles of human yolk sac 2023-08-16T04:00:00Z Neutrophils, eosinophils, lymphocytes, monocytes and basophils are all about three times the diameter of a red blood cell and round. Fundamentals of Biology 2015-01-01T00:00:00Z For example, a monocyte is a type of white blood cell that circulates in the blood and lymph and develops into a macrophage after it moves into infected tissue. Concepts of Biology 2013-04-25T00:00:00Z Doctors said the kind of leukemia afflicting Berlusconi usually appears in people of advanced age and is characterized by an increase in white blood cells known as monocytes. Italy’s former PM Berlusconi has leukemia, lung infection, doctors say 2023-04-06T04:00:00Z White blood cells—including neutrophils, monocytes, lymphocytes, eosinophils, and basophils—are involved in the immune response. Biology for AP Courses 2022-06-09T00:00:00Z Osteoclasts develop from monocytes and macrophages and differ in appearance from other bone cells. Anatomy and Physiology 2013-06-19T00:00:00Z When monocytes encounter an atherosclerotic plaque on the side of a blood vessel, they morph into macrophages and release inflammation-inciting molecules called cytokines. Immune Cells That Remember Inflammation Could Offer Treatment Targets for Atherosclerosis 2021-12-01T05:00:00Z Figure 17.11 Cells involved in the innate immune response include mast cells, natural killer cells, and white blood cells, such as monocytes, macrophages and neutrophils. Concepts of Biology 2013-04-25T00:00:00Z These molecules attract white blood cells known as monocytes, which take up residence in the artery wall. Inflammation in Heart Disease: Do Researchers Know Enough? 2021-12-01T05:00:00Z A monocyte is a type of white blood cell that circulates in the blood and lymph and differentiates into macrophages after it moves into infected tissue. Biology for AP Courses 2022-06-09T00:00:00Z The macrophage cell is a large cell derived from a monocyte, a type of blood cell, which enters the connective tissue matrix from the blood vessels. Anatomy and Physiology 2013-06-19T00:00:00Z To test this in people, the team analysed monocytes from 20 individuals with severe atherosclerosis3. Immune Cells That Remember Inflammation Could Offer Treatment Targets for Atherosclerosis 2021-12-01T05:00:00Z For example, HIV is able to penetrate the plasma membranes of specific kinds of white blood cells called T-helper cells and monocytes, as well as some cells of the central nervous system. Concepts of Biology 2013-04-25T00:00:00Z There, the monocytes become lipid-laden foam cells that send out more signalling molecules to keep inflammation going. Inflammation in Heart Disease: Do Researchers Know Enough? 2021-12-01T05:00:00Z Another leukocyte that is found in the peripheral blood is the monocyte. Biology for AP Courses 2022-06-09T00:00:00Z They are found on bone surfaces, are multinucleated, and originate from monocytes and macrophages, two types of white blood cells, not from osteogenic cells. Anatomy and Physiology 2013-06-19T00:00:00Z Cytokines produced as a result of these conditions can easily reach the bone marrow, Hajishengallis says, theoretically resulting in a long-lived supply of trained monocytes that can contribute to inflammation anywhere in the body. Immune Cells That Remember Inflammation Could Offer Treatment Targets for Atherosclerosis 2021-12-01T05:00:00Z The researchers found that infected children had lower levels of cells known as monocytes, including inflammatory monocytes, which act as a bridge between the innate and adaptive immune systems. Why Kids Beat Back COVID Better Than Adults 2021-09-15T04:00:00Z Another type of innate immune cell, called a monocyte, acts as a sort of cellular bouncer, getting rid of any infected cells it finds and signaling the adaptive immune response to shift into gear. How the Immune System of Older Adults Like Trump Weakens with Age 2020-10-02T04:00:00Z HIV is able to penetrate the plasma membranes of a subtype of lymphocytes called T-helper cells, as well as some monocytes and central nervous system cells. Biology for AP Courses 2022-06-09T00:00:00Z Agranular leukocytes include monocytes, which mature into macrophages that are phagocytic, and lymphocytes, which arise from the lymphoid stem cell line. Anatomy and Physiology 2013-06-19T00:00:00Z So for trained immunity to last for months, it must also affect monocyte precursor stem cells in the bone marrow. Immune Cells That Remember Inflammation Could Offer Treatment Targets for Atherosclerosis 2021-12-01T05:00:00Z The French researchers analyzed RNA in samples containing mixtures of immune cells, whereas the South Korean team sequenced RNA in individual cells and observed interferon differences in monocytes. An Immune Protein Could Prevent Severe COVID-19—if It Is Given at the Right Time 2020-07-28T04:00:00Z Previous work1,4 indicates that neutralizing a protein called CCL2, which is produced by the tumour and promotes monocyte accumulation in the lungs of mice, impairs metastasis in mouse tumour models. Tweaking the DNA of myeloid cells curbs cancer spread 2020-02-25T05:00:00Z Because of their role in monitoring the vasculature, monocytes are key to the development of atherosclerosis. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z Macrophages are monocytes that have left the circulation and phagocytize debris, foreign pathogens, worn-out erythrocytes, and many other dead, worn out, or damaged cells. Anatomy and Physiology 2013-06-19T00:00:00Z Because all cells use glycolysis and modify histones, however, researchers are also looking for ways to target these processes specifically in monocytes and their precursors. Immune Cells That Remember Inflammation Could Offer Treatment Targets for Atherosclerosis 2021-12-01T05:00:00Z Yet the Korean team’s single-cell profiling only looked at interferons’ effect on monocytes. An Immune Protein Could Prevent Severe COVID-19—if It Is Given at the Right Time 2020-07-28T04:00:00Z Consistent with previous studies4,5, the authors found that two types of myeloid cell — monocytes and neutrophils — accumulated in the lung before metastases were detectable there. Tweaking the DNA of myeloid cells curbs cancer spread 2020-02-25T05:00:00Z But because monocytes are crucial for host defence, eliminating them entirely is not therapeutically viable. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z Abnormally high counts of monocytes are associated with viral or fungal infections, tuberculosis, and some forms of leukemia and other chronic diseases. Anatomy and Physiology 2013-06-19T00:00:00Z When they tested the participants’ monocytes in the lab at the end of the programme, the team found that the cells produced lower levels of cytokines than before. Immune Cells That Remember Inflammation Could Offer Treatment Targets for Atherosclerosis 2021-12-01T05:00:00Z If the viruses thwart this antiviral defense, however, the delayed interferon response becomes pathogenic—summoning too many monocytes, which secrete inflammatory molecules and cause tissue damage. An Immune Protein Could Prevent Severe COVID-19—if It Is Given at the Right Time 2020-07-28T04:00:00Z Intriguingly, the authors found that the epigenetic therapy caused monocytes to differentiate into a type of cell called an interstitial macrophage, which might lack the ability to promote tumour establishment at a secondary site. Tweaking the DNA of myeloid cells curbs cancer spread 2020-02-25T05:00:00Z Identifying and blocking factors involved in monocyte recruitment to plaques might, however, be an alternative strategy. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z A monocyte is a circulating precursor cell that differentiates into either a macrophage or dendritic cell, which can be rapidly attracted to areas of infection by signal molecules of inflammation. Anatomy and Physiology 2013-06-19T00:00:00Z The immune system’s myeloid cells — a group that includes macrophages and monocytes — are exposed to a range of physical forces, for example those encountered when leaving blood vessels to enter tissues6. Pressure regulates immune-cell function 2019-08-20T04:00:00Z Here we have human monocytes, a type of white blood cell, that have been encapsulated in brown algae. A colourful sea of blood vessel cells wins science image competition 2019-08-13T04:00:00Z The drugs also caused this type of cellular conversion in monocytes that were experimentally transferred from the bone marrow of untreated mice to the bloodstream of drug-treated mice. Tweaking the DNA of myeloid cells curbs cancer spread 2020-02-25T05:00:00Z In parallel, the authors performed single-cell RNA sequencing of immune cells retrieved from plaques, and found an increase in platelet-specific factor Pf4 on macrophages, suggesting that platelet adherence persisted beyond monocyte recruitment. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z To study macrophages, the authors began by focusing on a protein called CX3CR1, which is expressed on monocytes and macrophages. Macrophages form a protective cellular barrier in joints 2019-08-06T04:00:00Z However, depleting monocytes caused a reduction in the levels of endothelin 1, implicating the cells as a source of this hormone. Pressure regulates immune-cell function 2019-08-20T04:00:00Z The reduced inflammation was accompanied by a decrease in immune cells such as neutrophils, monocytes and macrophages, which are major drivers of inflammation. Two types of fibroblast drive arthritis 2019-05-28T04:00:00Z This treatment decreased the expression of CCR2 in monocytes and CXCR2 in neutrophils, and fewer of these cells reached the lung. Tweaking the DNA of myeloid cells curbs cancer spread 2020-02-25T05:00:00Z In plaques, monocytes ingest lipids and transform into macrophage cells. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z Immune cells—in particular, white blood cells called monocytes—also play a key role. Poor sleep could clog your arteries. A mouse study shows how that might happen 2019-02-13T05:00:00Z Mature neutrophils and monocytes migrate to arterial walls, where the monocytes develop into macrophage cells. How broken sleep promotes cardiovascular disease 2019-02-12T05:00:00Z One reason for this accuracy, Kramer says, is that the researchers extract just one cell type—monocytes, which display strong circadian oscillations—from blood. A Blood Test for the Body's Clock 2018-12-28T05:00:00Z The epigenetic therapy also caused some monocytes to differentiate into a cell called an interstitial macrophage. Tweaking the DNA of myeloid cells curbs cancer spread 2020-02-25T05:00:00Z For instance, it is unclear precisely how platelets foster monocyte recruitment and how they reprogram macrophages. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z The clearest effects showed up in monocytes—a group of white blood cells that chew up pathogens as part of the body’s non-specific immune defenses. Could Brain Stimulation Slow Cancer? 2018-07-13T04:00:00Z Some controversy currently exists about whether MDSCs are a cell population that is distinct from normal neutrophils and monocytes, given that MDSCs are highly similar to those cells, yet are considered functionally different. Resistance to prostate-cancer treatment is driven by immune cells 2018-06-26T04:00:00Z First, it is clear that many of the current categories of immune cells, such as T cells or monocytes, encompass heterogeneous populations. Immunology, one cell at a time 2017-07-02T04:00:00Z The impaired recruitment of tumour-promoting monocytes and neutrophils to the lungs was accompanied by a decrease in the number and size of metastases. Tweaking the DNA of myeloid cells curbs cancer spread 2020-02-25T05:00:00Z Finally, future work will need to determine whether this phenomenon occurs broadly in other situations involving monocyte recruitment and consequent macrophage activity, for instance in infected or injured tissue. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z Specifically, the team found that monocytes from brain-activated mice killed bacteria much more effectively than monocytes from untreated animals. Could Brain Stimulation Slow Cancer? 2018-07-13T04:00:00Z The researchers grew a different type of immune cells called monocytes in a dish and infected them with bacteria and viruses. Neanderthal DNA affects ethnic differences in immune response 2016-10-19T04:00:00Z Other blood cells called monocytes were found in similar numbers in both groups. Can house dust explain why Amish protected from asthma? 2016-08-03T04:00:00Z The abnormalities were discovered in monocytes, a type of white blood cell, produced in the bone marrow, that is dramatically changed in people who are socially isolated. Loneliness grows from individual ache to public health hazard 2016-01-31T05:00:00Z Nevertheless, the study builds on a long line of work implicating platelets, monocytes and macrophages as key contributors to atherosclerosis. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z The macrophage and monocyte categories are computed relative to microglia49, 50. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease : Nature : Nature Publishing Group 2015-02-17T05:00:00Z This meant higher levels of three types of white blood cells that are integral to good immune function: leukocytes, monocytes and so-called "natural killer" cells. Binge Drinking May Weaken Immune System, Study Suggests 2015-01-05T05:00:00Z Other targets include monocytes and macrophages, types of white blood cells whose job is to absorb and clear away foreign organisms. How Ebola Blindsides the Body's Defenses 2014-11-07T05:00:00Z However, immature monocytes cause inflammation and reduce antibody protection. Loneliness grows from individual ache to public health hazard 2016-01-31T05:00:00Z The conceptual power of exploring how immune and blood-clotting pathways intersect, the insights into monocyte and macrophage function, and the corroborating human data, are all worthy of further exploration. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z The macrophage and monocyte categories are computed relative to microglia49, 50. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease : Nature : Nature Publishing Group 2015-02-17T05:00:00Z The Ebola virus is usually transmitted by close contact and the first cells it affects are cells important to your primary immune response—monocytes, macrophages and dendritic cells. When Will We Have a Vaccine for Ebola Virus? 2014-07-29T04:00:00Z Here, they showed that the virus was hiding in other infection-fighting white blood cells called monocytes and macrophages. Joep Lange, The Physician-Scientist Before The Medical Diplomat 2014-07-20T04:00:00Z “It became B cells and T cells, and monocytes, and macrophages. And macrophages became dendritic cells, and T cells became regulatory T cells and killer T cells,” he says. Cell physiology: The changing colour of fat 2014-04-16T17:21:54.590Z This movement is aided by endothelial cells, which demarcate the border between blood and tissue, and which produce a panoply of monocyte-attracting chemical messengers, enabling monocyte surveillance of and migration across the blood-vessel wall. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z More than half of cis-eQTLs identified, involving hundreds of genes and associated pathways, are detected specifically in stimulated monocytes. [Research Article] Innate Immune Activity Conditions the Effect of Regulatory Variants upon Monocyte Gene Expression 2014-03-06T20:26:02.685Z Together, these data highlight the intricate interplay between scavenger receptors, the spleen, and inflammatory monocyte function and support the translation of IMPs for therapeutic use in diseases caused or potentiated by inflammatory monocytes. [Research Articles] Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles 2014-01-15T19:25:14.253Z At the same time, endothelial and smooth muscle cells begin to pump out chemicals that attract monocytes. Pathology: At the heart of the problem 2013-01-30T18:23:07.253Z The selectivity of drug action is due to profound up-regulation of CD73 and adenosine AR expression in neutrophils and inflammatory monocytes as found in recovered cells from the synovial fluid of arthritic mice. [Research Articles] Selective Activation of Adenosine A2A Receptors on Immune Cells by a CD73-Dependent Prodrug Suppresses Joint Inflammation in Experimental Rheumatoid Arthritis 2012-08-08T18:55:12.537Z Platelets — blood-cell fragments best known for making blood clots — likewise help monocytes to infiltrate the vessel wall by adhering to the cells to form monocyte–platelet aggregates. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z The differential showed a virtual absence of polymorphs, lymphocytes and monocytes. Pandemic Subsequently, these monocytes no longer trafficked to sites of inflammation; rather, IMP infusion caused their sequestration in the spleen through apoptotic cell clearance mechanisms and, ultimately, caspase-3–mediated apoptosis. [Research Articles] Therapeutic Inflammatory Monocyte Modulation Using Immune-Modifying Microparticles 2014-01-15T19:25:14.253Z These newly recruited monocytes enter the arterial wall and mature into macrophages, which gorge on LDL cholesterol and balloon in size. Pathology: At the heart of the problem 2013-01-30T18:23:07.253Z These cells travel to the spleen and become monocytes. Pathology: At the heart of the problem 2013-01-30T18:23:07.253Z The LDL in artery walls prompts endothelial cells, which line the vessels, to produce sticky molecules that snag macrophage precursor cells, monocytes, from the blood. Pathology: At the heart of the problem 2013-01-30T18:23:07.253Z |
| 随便看 |
英语例句辞典收录了117811条英语例句在线翻译词条，基本涵盖了全部常用单词及词组的例句翻译及用法，是英语学习的有利工具。