| 单词 | mitotic |
| 例句 | The process, called mitotic reprogramming, sheds light on the future of reproductive technology. A masculine conception: Women may not be needed in the future of baby-making 2016-09-14T04:00:00Z "There's still a lot of the scientific community that's investigating mitotic arrest as a mechanism to kill tumors," Weaver says. Common chemotherapy drugs don't work like doctors thought, with big implications for drug discovery 2023-10-26T04:00:00Z The female gametophyte is formed from mitotic divisions of the megaspore, forming an eight-nuclei ovule sac. Fundamentals of Biology 2015-01-01T00:00:00Z During the mitotic phase, the replicated DNA and cytoplasmic contents are separated and the cell divides. Concepts of Biology 2013-04-25T00:00:00Z During the mitotic phase, the duplicated chromosomes are segregated and distributed into daughter nuclei. Biology for AP Courses 2022-06-09T00:00:00Z They are important in cell division, forming a structure called the mitotic spindle that separates chromosomes. Miller & Levine Biology 2018-01-01T00:00:00Z This migration occurs because the chromosomes are attached to a cellular machine known as the mitotic spindle. Common chemotherapy drugs don't work like doctors thought, with big implications for drug discovery 2023-10-26T04:00:00Z These osteogenic cells are undifferentiated with high mitotic activity and they are the only bone cells that divide. Anatomy and Physiology 2013-06-19T00:00:00Z For a cell to move from interphase to the mitotic phase, many internal and external conditions must be met. Concepts of Biology 2013-04-25T00:00:00Z In order for a cell to move from interphase into the mitotic phase, many internal and external conditions must be met. Biology for AP Courses 2022-06-09T00:00:00Z When this protein is present, the mitotic spindle forms and the mitosis phase of the cell cycle is activated. Miller & Levine Biology 2018-01-01T00:00:00Z But, using fast live imaging, the group that performed the current study showed previously3 that the apical domain is transiently lost during mitotic cell division, before re-forming in the daughter cells on the embryo’s periphery. Developing cells remember where they came from, thanks to keratin filaments 2020-08-25T04:00:00Z You can also see how that organization breaks down when cancer takes over the regular mitotic functioning of a cell. Anatomy and Physiology 2013-06-19T00:00:00Z Some cell organelles are duplicated, and the cytoskeleton is dismantled to provide resources for the mitotic spindle. Concepts of Biology 2013-04-25T00:00:00Z Some cell organelles are duplicated, and the cytoskeleton is dismantled to provide resources for the mitotic phase. Biology for AP Courses 2022-06-09T00:00:00Z Paramecia and most ciliates reproduce asexually by mitotic cell division. Miller & Levine Biology 2018-01-01T00:00:00Z In those cases, in order to impose a reproducible division asymmetry, the mitotic apparatus itself is oriented so that daughter cells inherit different complements of cortically localized cell-fate determinants9. Developing cells remember where they came from, thanks to keratin filaments 2020-08-25T04:00:00Z After fertilization the zygote gives rise to rapid mitotic cycles, generating many cells to form the embryo. Anatomy and Physiology 2013-06-19T00:00:00Z The first portion of the mitotic phase, mitosis, is composed of five stages, which accomplish nuclear division. Concepts of Biology 2013-04-25T00:00:00Z The final preparations for the mitotic phase must be completed before the cell is able to enter the first stage of mitosis. Biology for AP Courses 2022-06-09T00:00:00Z Ramos’s main inspirations, however, were video clips of a ‘mitotic wave’, in which a tide of nuclear division ripples across the embryo from edges to centre. The sounds of science: biochemistry and the cosmos inspire new music 2019-05-06T04:00:00Z Heterogeneity within mitotic progenitors in the ganglionic eminences is driven by a highly conserved maturation trajectory, alongside eminence-specific transcription factor expression that seeds the emergence of later diversity. Developmental diversification of cortical inhibitory interneurons 2018-03-04T05:00:00Z The green stain reveals mitotic spindles, red is the cell membrane and part of the cytoplasm, and the structures that appear light blue are chromosomes. Anatomy and Physiology 2013-06-19T00:00:00Z The second portion of the mitotic phase, called cytokinesis, is the physical separation of the cytoplasmic components into two daughter cells. Concepts of Biology 2013-04-25T00:00:00Z Microtubules that will form the mitotic spindle extend between the centrosomes, pushing them farther apart as the microtubule fibers lengthen. Biology for AP Courses 2022-06-09T00:00:00Z Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells. Chromosomal instability drives metastasis through a cytosolic DNA response 2018-01-16T05:00:00Z This file contains differentially expressed TFs across eminences within mitotic cells. Developmental diversification of cortical inhibitory interneurons 2018-03-04T05:00:00Z The mitotic spindle is the structure composed of the centrosomes and their emerging microtubules. Anatomy and Physiology 2013-06-19T00:00:00Z The kinetochore becomes attached to the mitotic spindle. Concepts of Biology 2013-04-25T00:00:00Z The technician will see mostly mitotic cells in the root cap. Biology for AP Courses 2022-06-09T00:00:00Z One possible explanation is that the DNA repair response is different in germ cell meiotic M phase compared to mitotic M phase in cultured cells. Correction of a pathogenic gene mutation in human embryos : Nature : Nature Research 2017-08-01T04:00:00Z This file contains temporally regulated genes in mitotic GE cells and and their MT bin of maximal expression. Developmental diversification of cortical inhibitory interneurons 2018-03-04T05:00:00Z Near the end of prophase there is an invasion of the nuclear area by microtubules from the mitotic spindle. Anatomy and Physiology 2013-06-19T00:00:00Z The kinetochore becomes attached to the mitotic spindle. Concepts of Biology 2013-04-25T00:00:00Z The technician will see that most mitotic cells are in the maturation zone. Biology for AP Courses 2022-06-09T00:00:00Z The cells show abundant eosinophilic cytoplasm with pleomorphic nuclei and prominent mitotic figures. Integrated genomic and molecular characterization of cervical cancer : Nature : Nature Research 2017-01-22T05:00:00Z Below that was this: “All lymph nodes are prominent. There is a remarkably high mitotic rate.” Our Dog Has Cancer and We're Not Treating It 2014-11-13T05:00:00Z The kinetochore is a protein structure on the centromere that is the point of attachment between the mitotic spindle and the sister chromatids. Anatomy and Physiology 2013-06-19T00:00:00Z The microtubules that form the basis of the mitotic spindle extend between the centrosomes, pushing them farther apart as the microtubule fibers lengthen. Concepts of Biology 2013-04-25T00:00:00Z The mitotic spindle continues to develop as more microtubules assemble and stretch across the length of the former nuclear area. Biology for AP Courses 2022-06-09T00:00:00Z The cells show abundant eosinophilic cytoplasm with pleomorphic nuclei and prominent mitotic figures. Integrated genomic and molecular characterization of cervical cancer : Nature : Nature Research 2017-01-22T05:00:00Z Perhaps melanomas with high mitotic rates will be treated differently than those with lower rates, she added. High-Risk Melanomas Often on Head or Neck, Study Finds 2014-08-20T04:00:00Z Nucleoli also reappear within the new nuclei, and the mitotic spindle breaks apart, each new cell receiving its own complement of DNA, organelles, membranes, and centrioles. Anatomy and Physiology 2013-06-19T00:00:00Z The nuclei resulting from a mitotic division are genetically identical to the original. Concepts of Biology 2013-04-25T00:00:00Z The proteins of the kinetochore attract and bind mitotic spindle microtubules. Biology for AP Courses 2022-06-09T00:00:00Z Closely set, atypical glands with enlarged nuclei and scattered mitotic figures infiltrate through the connective tissue of the cervix. Integrated genomic and molecular characterization of cervical cancer : Nature : Nature Research 2017-01-22T05:00:00Z Rapid cell growth -- called "high mitotic rate" -- is associated with poorer prognosis in patients with melanoma. High-Risk Melanomas Often on Head or Neck, Study Finds 2014-08-20T04:00:00Z However, we determine here that paclitaxel levels in primary breast tumors are well below those required to elicit sustained mitotic arrest. [Research Articles] Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles 2014-03-26T19:25:11.015Z During anaphase II, as in mitotic anaphase, the kinetochores divide and one sister chromatid is pulled to one pole and the other sister chromatid is pulled to the other pole. Concepts of Biology 2013-04-25T00:00:00Z Once a mitotic fiber attaches to a chromosome, the chromosome will be oriented until the kinetochores of sister chromatids face the opposite poles. Biology for AP Courses 2022-06-09T00:00:00Z The tall columnar tumour cells show basally placed, crowded, enlarged nuclei that show frequent mitotic figures. Integrated genomic and molecular characterization of cervical cancer : Nature : Nature Research 2017-01-22T05:00:00Z The American Academy of Dermatology says inclusion of mitotic rate in skin cancer reports is an option, he noted. High-Risk Melanomas Often on Head or Neck, Study Finds 2014-08-20T04:00:00Z Contrary to the previous hypothesis, we find that mitotic arrest is dispensable for tumor regression in patients. [Research Articles] Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles 2014-03-26T19:25:11.015Z The mitotic phase is a multistep process during which the duplicated chromosomes are aligned, separated, and moved to opposite poles of the cell, and then the cell is divided into two new identical daughter cells. Concepts of Biology 2013-04-25T00:00:00Z The nuclei resulting from a mitotic division are genetically identical to the original nucleus. Biology for AP Courses 2022-06-09T00:00:00Z Closely set, atypical glands with enlarged nuclei and scattered mitotic figures infiltrate through the connective tissue of the cervix. Integrated genomic and molecular characterization of cervical cancer : Nature : Nature Research 2017-01-22T05:00:00Z "This study shows a possible particular behavior for mitotically active melanoma, but more studies are needed to define whether mitotic rates should become a standard independent factor in these tumors," Al Moutran said. High-Risk Melanomas Often on Head or Neck, Study Finds 2014-08-20T04:00:00Z The blockbuster chemotherapy drug paclitaxel is widely presumed to cause cell death in tumors as a consequence of mitotic arrest, as it does at concentrations routinely used in cell culture. [Research Articles] Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles 2014-03-26T19:25:11.015Z The mitotic spindles are broken down into monomers that will be used to assemble cytoskeleton components for each daughter cell. Concepts of Biology 2013-04-25T00:00:00Z The chance of this disorder increases with age due to increased mistakes in the mitotic cells with age. Biology for AP Courses 2022-06-09T00:00:00Z The tall columnar tumour cells show basally placed, crowded, enlarged nuclei that show frequent mitotic figures. Integrated genomic and molecular characterization of cervical cancer : Nature : Nature Research 2017-01-22T05:00:00Z But this mitotic capacity is one factor which lets us transplant everyone with cells from the same source. A Closer Look At Neuralstem's ALS Treatment 2013-11-21T16:10:00Z Therefore, the relative contributions of mitotic defects and pre-mitotically generated structural chromosome abnormalities to chromosomal instability in tumours need to be explored. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z The mitotic spindle separates the chromosomes and elongates the cell. Concepts of Biology 2013-04-25T00:00:00Z During the mitotic phase, the replicated DNA and cytoplasmic contents are separated, and the cell divides. Biology for AP Courses 2022-06-09T00:00:00Z Among its functions, this protein regulates the mitotic spindle and hence the crucial balance between cell proliferation and differentiation – vital not only for cancer, but also for correct brain development. Floating Brains and Invasive Minds 2013-09-09T15:45:09.203Z Karsenti was interested in mitosis — the process of cell division — particularly in the mitotic spindle, an intricate structure that forms during cell division to ensure that new cells inherit only one copy of each chromosome. Systems ecology: Biology on the high seas 2013-09-04T17:20:24.237Z Mitotic defects result in inaccurate partitioning of whole chromosomes between daughter cells — mediated through incorrect attachment of chromosomes to the mitotic spindle. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z The kinetochore becomes attached to the mitotic spindle. Concepts of Biology 2013-04-25T00:00:00Z The two centrosomes will give rise to the mitotic spindle, the apparatus that orchestrates the movement of chromosomes during mitosis. Biology for AP Courses 2022-06-09T00:00:00Z Such relaxation of constraints on genome structure is reminiscent of other mitotic lineages such as cancer cells and somatic tissues. Genomic evidence for ameiotic evolution in the bdelloid rotifer Adineta vaga 2013-08-21T17:50:58.107Z He also saw links to his own work on the mitotic spindle, which meets three key criteria for a self-organizing system. Systems ecology: Biology on the high seas 2013-09-04T17:20:24.237Z DNA methylation is a covalent base modification of plant nuclear genomes that is accurately inherited through both mitotic and meiotic cell divisions. Patterns of population epigenomic diversity 2013-03-13T18:21:41.540Z While many single-celled organisms and a few multicellular organisms can produce genetically identical clones of themselves through mitotic cell division, many single-celled organisms and most multicellular organisms reproduce regularly using another method. Concepts of Biology 2013-04-25T00:00:00Z The first portion of the mitotic phase is called karyokinesis, or nuclear division. Biology for AP Courses 2022-06-09T00:00:00Z In these experiments the criterion for gene retention was the differentiation of functional muscle and nerve cells by nuclei whose mitotic ancestors had already promoted the differentiation of intestine cells. Transplanted Nuclei and Cell Differentiation, by Sir John B. Gurdon 2012-10-09T23:45:00.177Z Novel classes of drugs such as mitotic checkpoint kinase or kinesin inhibitors, which target the maintenance of tetraploidy through successive cell divisions, may therefore represent a rational therapeutic strategy in these cases. Dissecting the genomic complexity underlying medulloblastoma 2012-08-01T17:52:34.853Z Our experiments suggest that targeting the mitotic fission of mitochondria may be a complementary approach to halt cancer cell proliferation. Dynamic Mitochondrial Networks in Cancer 2012-03-29T15:45:03.977Z In multicellular organisms, the new diploid cell will then undergo mitotic cell divisions to develop into an adult organism. Concepts of Biology 2013-04-25T00:00:00Z What mitotic structure is targeted by these drugs, and what effect would this have on cell division? Biology for AP Courses 2022-06-09T00:00:00Z The achromatic figure, formed in mitotic cellÐdivision, consisting of two asters connected by a spindleÐshaped bundle of rodlike fibers diverging from each aster, and called the spindle. Webster's Unabridged Dictionary 2012-03-24T02:00:23.513Z The prophase covers all changes up to the completion of the mitotic figure. Encyclopaedia Britannica, 11th Edition, Volume 7, Slice 8 "Cube" to "Daguerre, Louis" 2012-01-31T03:00:17.257Z Relative 2HG levels from pathologically confirmed mutant tissues correlated with levels of other ex vivo metabolites and histopathology parameters associated with increases in mitotic activity, relative tumor content, and cellularity. [Research Articles] Magnetic Resonance of 2-Hydroxyglutarate in IDH1-Mutated Low-Grade Gliomas 2012-01-11T20:25:08.257Z Overall, meiosis II resembles the mitotic division of a haploid cell. Concepts of Biology 2013-04-25T00:00:00Z It is not visually possible to separate the stages of interphase from each other, but the mitotic stages are readily identifiable. Biology for AP Courses 2022-06-09T00:00:00Z By successive divisions, usually mitotic, the zygote-nucleus gives rise to eight daughter-nuclei, each of which becomes the nucleus of a sporozoite. Encyclopaedia Britannica, 11th Edition, Volume 12, Slice 5 "Greek Law" to "Ground-Squirrel" 2011-12-05T03:00:51.527Z Various elaborate theories have been propounded to explain the mechanism of the mitotic figure. Encyclopaedia Britannica, 11th Edition, Volume 7, Slice 8 "Cube" to "Daguerre, Louis" 2012-01-31T03:00:17.257Z Each nucleus aggregates around it a proper zone of dense protoplasm; by two successive mitotic divisions each mass becomes quadri-nucleate, and splits up into four biflagellate, uninucleate zoospores. Encyclopaedia Britannica, 11th Edition, Volume 10, Slice 6 "Foraminifera" to "Fox, Edward" 2011-04-22T02:00:08.637Z The kinetochore becomes attached to the mitotic spindle. Concepts of Biology 2013-04-25T00:00:00Z Chromosomes attach to the mitotic spindle, which separates the chromosomes and elongates the cell. Biology for AP Courses 2022-06-09T00:00:00Z It is an essential constituent of the nucleus, and a meager supply of phosphorus retards, or inhibits, mitotic cell-division. The Chemistry of Plant Life It is indeed usually assumed that the mitotic mechanism is not merely for the distribution, but for the equal distribution, of the sister granules to the two daughter nuclei. Encyclopaedia Britannica, 11th Edition, Volume 7, Slice 8 "Cube" to "Daguerre, Louis" 2012-01-31T03:00:17.257Z It has been long known that the mitotic processes of cancer and the forming and dividing of the chromosomes were riotous and irregular, like the rest of its growth. Preventable Diseases Prokaryotic cells, on the other hand, do not undergo mitosis and therefore have no need for a mitotic spindle. Concepts of Biology 2013-04-25T00:00:00Z The mitotic spindle draws the duplicated chromosomes to the opposite ends of the cell followed by formation of a septum and two daughter cells. Biology for AP Courses 2022-06-09T00:00:00Z Three mitotic divisions produce eight nuclei in seven cells. Concepts of Biology 2013-04-25T00:00:00Z The undivided, i.e. unripe, chromosomes are therefore incapable of utilizing the mitotic mechanism for such a transverse fission as Weismann originally postulated. Encyclopaedia Britannica, 11th Edition, Volume 7, Slice 8 "Cube" to "Daguerre, Louis" 2012-01-31T03:00:17.257Z The second division of meiosis is much more similar to a mitotic division. Concepts of Biology 2013-04-25T00:00:00Z Chromosomes attach to the mitotic spindle, which separates them and elongates the cell. Concepts of Biology 2013-04-25T00:00:00Z In most plants and animals, through multiple rounds of mitotic cell division, this diploid cell will develop into an adult organism. Biology for AP Courses 2022-06-09T00:00:00Z The technician will observe mitotic figures in the meristematic tissue below the cap. Biology for AP Courses 2022-06-09T00:00:00Z The precise timing and formation of the mitotic spindle is critical to the success of eukaryotic cell division. Biology for AP Courses 2022-06-09T00:00:00Z Prokaryotic cells, on the other hand, do not undergo karyokinesis and therefore have no need for a mitotic spindle. Biology for AP Courses 2022-06-09T00:00:00Z The kinetochore becomes attached to the mitotic spindle. Concepts of Biology 2013-04-25T00:00:00Z The second division of meiosis is more similar to a mitotic division, except that the daughter cells do not contain identical genomes because of crossover. Biology for AP Courses 2022-06-09T00:00:00Z The mitotic spindle passes through the envelope and elongates the cell. Biology for AP Courses 2022-06-09T00:00:00Z A mitotic spindle forms from the centrioles and passes through the nuclear membrane, which remains intact. Biology for AP Courses 2022-06-09T00:00:00Z Chromosomes attach to the mitotic spindle, which separates the chromosomes and elongates the cell. Biology for AP Courses 2022-06-09T00:00:00Z The kinetochore becomes attached to the mitotic spindle. Concepts of Biology 2013-04-25T00:00:00Z Chromosomal crossover occurs during the mitotic process when chromosomes are linked together and recombination takes place, increasing the variance of genetic combinations in the haploid mitotic cells formed from mitosis. Biology for AP Courses 2022-06-09T00:00:00Z Meiosis II is much more analogous to a mitotic division. Biology for AP Courses 2022-06-09T00:00:00Z Exactly what mitotic structure do these drugs target, and what effect would that have on cell division? Biology for AP Courses 2022-06-09T00:00:00Z During meiosis II—which is more similar to a mitotic division—the chromatids separate and segregate into four haploid sex cells. Biology for AP Courses 2022-06-09T00:00:00Z |
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