| 单词 | microscopy |
| 例句 | Micrographia really did mark the moment when microscopy came of age as a scientific discipline. The Scientists 2003-10-21T00:00:00Z Thus, for relief, Maurice had taken up interference microscopy to find a trick for weighing chromosomes. Double Helix 1968-02-27T00:00:00Z We used X-ray fluorescence, X-Ray diffraction techniques, electronic and optical microscopy. Exclusive: Romanian expert believes three artworks from Dutch heist destroyed 2013-07-22T15:14:51Z It includes 10 essays, by scientists and literary scholars, seeking to translate Nabokov’s adventures in microscopy into a readily visible context. Fine Lines: Vladimir Nabokov’s Scientific Art 2016-03-17T04:00:00Z She was a graduate student at Einstein then, and he had been newly hired as the training director of microscopy there. After 25 Years Together, Why Marry? Why Not? 2017-04-07T04:00:00Z Walter Reed was “a professor of clinical microscopy at the Army Medical School, what is now the Walter Reed Army Institute of Research,” Schierkolk said. Eight U.S. museums that chronicle and celebrate the history of medicine 2021-08-05T04:00:00Z A celebratory primer on polarized light microscopy and other cumbersomely termed diagnostic tools employed by conservators today to determine when and how a picture was made, the show may sound like homework. Abroad: Testing Art for Authenticity at London?s National Gallery 2010-07-12T16:06:00Z Thanks in part to the computer colouring and the almost unnatural-seeming level of resolution, many of these photographs look like images from electron microscopy. Abstract and affecting, the new Mars pictures are a confrontation with the sublime | Sam Leith 2010-03-21T22:30:00Z Using advanced microscopy, researchers witnessed the formation of new connections between the brain's synapses during sleep, proving the key role of sleep in creating memories. Sleep's role in memory formation discovered: do you get enough? 2014-06-06T04:00:00Z This undated photo provided by Australian Synchrotron and the National Gallery of Victoria shows an image appears, with X-ray fluorescence microscopy, beneath Edgar Degas' Portrait of a Woman. X-ray uncovers hidden portrait beneath famed Degas painting 2016-08-05T04:00:00Z And not only do you want to read every word, but you find yourself relishing terms such as dendrochronology, Raman microscopy and energy dispersive X-ray spectrometry. National Gallery's forgeries are the real deal 2010-07-01T14:45:00Z The Ancient Ink Laboratory, a collaboration between Columbia University and New York University, is using nondestructive techniques like micro Raman spectroscopy, microscopy and infrared photography to scrutinize inks on documents. Solving the Mystery of Ancient Ink Origins 2016-05-05T04:00:00Z Today, techniques involving infrared imaging, as well as x-ray photography, electron microscopy and mass spectrometry, many of them pioneered by the National Gallery, are mainstays in the business of art curation. What lies beneath 2010-06-19T23:05:00Z The image of a close-up view of the heart of a mosquito, involved the use of a technique known as fluorescence microscopy. Life through a high powered lens: the Nikon Small World awards 2010-10-23T23:06:00Z Using advanced microscopy, analytical, and chemical techniques, the research team verified the validity of their proposed approach. Engineering bacteria to biosynthesize intricate protein complexes 2023-11-15T05:00:00Z The researchers in Cologne used the cryo-electron microscopy platform of their university to visualize the three-dimensional structure of the L-Cry protein under different light conditions. How marine bristle worms use a special protein to distinguish between sunlight and moonlight 2023-11-13T05:00:00Z “Accurate mold identification requires microscopy observation and other laboratory techniques, and is best left to trained professionals,” Lambertini says. What to do when you see mold on your food 2023-11-10T05:00:00Z Then, using fluorescence microscopy, the team revealed the presence of oxytocin directly on human intestinal organoids, also called mini guts, which are laboratory models of intestinal tissue that recapitulate many of its functions and structure. Research connecting gut bacteria and oxytocin provides a new mechanism for microbiome-promoted health benefits 2023-11-02T04:00:00Z "It wipes out the bacteria -- sterilizes the culture with a single dose of light. And then when you look at what occurs with electron microscopy, you see the collapse of the chromosome." New antibiotic approach proves promising against lyme bacterium 2023-11-02T04:00:00Z They chemically synthesized these candidate compounds and analyzed their binding structures to proteins using cryo-electron microscopy. Scientists build on artificial intelligence to create next-generation gastric acid treatment 2023-10-26T04:00:00Z The researchers used live microscopy to watch the migration of live breast cancer cells in two different systems modeled after the human body. Mechanics of breast cancer metastasis discovered, offering target for treatment 2023-10-27T04:00:00Z Next, using muscle proteins and advanced microscopy, the research team wanted to determine how temperature affects skeletal muscle: do skeletal muscles have similar temperature sensitivity, or are they different from the muscles of the heart? New evidence explains how warming-up enhances muscle performance 2023-10-25T04:00:00Z With the assistance of cryo-electron microscopy, the scientists have now been able to decode the structure of an important sperm membrane transporter at the molecular level. Membrane transporter ensures mobility of sperm cells 2023-10-26T04:00:00Z For this, Ali turned to a new microscopy tool called lattice light sheet 4D imaging that uses multiple sheets of laser light to create fully dimensional images of components inside living cells. Peering inside cells to see how they respond to stress 2023-10-16T04:00:00Z Furthermore, to gain insights into the binding mechanism, the research group employed cryo-electron microscopy to visualize the molecule's interaction with the gastric proton pump. Scientists build on artificial intelligence to create next-generation gastric acid treatment 2023-10-26T04:00:00Z They further characterized the nanomaterial with scanning and transmission electron microscopy, which sends beams of electrons at the material to form an image. Titanium oxide material can remove toxic dyes from wastewater 2023-10-10T04:00:00Z Researchers using a technique called two-photon microscopy can observe this process in living cells by following the formation and regression of spines on the neurons. Psychedelics plus psychotherapy can trigger rapid changes in the brain. Here's how 2023-10-06T04:00:00Z Furthermore, the presence of biological particles was confirmed through various methodologies, including electron microscopy and the detection of specific substances, such as the sugar alcohol compounds arabitol and mannitol. Biological particles play crucial role in Arctic cloud ice formation 2023-09-28T04:00:00Z To this end the researchers used the cryogenic electron microscopy method. A close-up of biological nanomachines: Researchers take a deep look at peroxisomal processes 2023-09-27T04:00:00Z Researchers leveraged state-of-the-art cryogenic electron microscopy to reveal the structure in its natural state, rather than earlier techniques that required crystallizing vast quantities of identical molecules to form an artificial picture of their native structure. Structure of crucial receptor in brain development, function 2023-09-20T04:00:00Z "Our experiments show that photocurrent streamline microscopy is a robust new experimental tool to visualize a photocurrent in quantum materials. This tool helps us look at how electrons behave badly." Electrons take flight at the nanoscale 2023-09-19T04:00:00Z HBP researchers have also developed unique algorithms that can build a full-scale scaffold model of brain regions from microscopy images. Scientists Tried to Re-create an Entire Human Brain in a Computer. What Happened? 2023-08-24T04:00:00Z Next they used electron microscopy to find out what was actually keeping the SWS1 in place—specifically, what cell it might be part of. How a Color-Changing Hogfish Knows whether Its Skin Is White, Brown or Polka-Dotted 2023-08-22T04:00:00Z Flavell and his colleagues combined past work in brain mapping and neuron labeling with recently developed microscopy methods that have enabled the brain of a C. elegans to be scanned as the worm moves. Worm Brains, Decoded like Never Before, Could Shed Light on Our Own Mind 2023-08-21T04:00:00Z “Yet over the course of her young life, she became a renowned expert in microscopy, writing the go-to texts used in the same schools that wouldn’t admit her.” Travel, nature, history, imagination infuse new wallpapers that help rooms tell stories 2023-07-26T04:00:00Z Traditionally working out those structures was done using electron microscopy and X-ray crystallography, a process which could take years. How the power of protein is being uncovered 2023-05-18T04:00:00Z Antonie van Leeuwenhoek revealed by means of microscopy the previously unknown world of microorganisms, laying the groundwork for cell theory. Fundamentals of Biology 2015-01-01T00:00:00Z Because light entering a specimen from below is focused onto the eye of an observer, the specimen can be viewed using light microscopy. Concepts of Biology 2013-04-25T00:00:00Z The researchers also used electron microscopy and computed tomography scans to probe the porous structure of the onggi and calculate its “gas permeability coefficient,” or how easily gas could pass through it. Science Shows Why Traditional Kimchi Making Works So Well 2023-05-16T04:00:00Z One time, she says, he came into the small, dark microscopy room where she was working and stood extremely close to her. NIH rules are supposed to stop ‘pass the harasser.’ In one recent case, they appear to have failed 2023-04-23T04:00:00Z To find out, he and colleagues gave the mice ovalbumin—the main protein found in egg whites and a known trigger of anaphylaxis—and used electrodes and microscopy to record and measure neuron activity. Nervous system may play role in severe allergic reactions 2023-03-16T04:00:00Z Skeletal muscle is called ‘striated’ because of the longitudinally striped appearance under light microscopy. Fundamentals of Biology 2015-01-01T00:00:00Z Preparation of a specimen for viewing under an electron microscope will kill it; therefore, live cells cannot be viewed using this type of microscopy. Concepts of Biology 2013-04-25T00:00:00Z In the nearly 50 years he’s been studying amber, advances in microscopy have made once-hidden details of ancient organisms dramatic and clear. A Fossil Flower Trapped in Amber Had a Mistaken Identity for 150 Years 2023-01-12T05:00:00Z She says most microscopy researchers examine microbes suspended in place by a preservative chemical, but this study followed living, moving organisms: “When I saw the images in the paper, I was blown away.” Bacteria and Fungi Can ‘Walk’ across the Surface of Our Teeth 2022-12-20T05:00:00Z We are researchers who specialize in microscopy and vaccine design. Scientists uncovered the structure of the key protein for a future hepatitis C vaccine — here’s how 2022-12-13T05:00:00Z Its scientists spurred advances in microscopy, cancer and tropical disease research. Inside Google’s quest to digitize troops’ tissue samples 2022-12-13T05:00:00Z Figure 6.4 Animal cell mitosis is divided into five stages—prophase, prometaphase, metaphase, anaphase, and telophase—visualized here by light microscopy with fluorescence. Concepts of Biology 2013-04-25T00:00:00Z Researchers were able to verify these orientations through atomic-force microscopy—a technique that generates images by tracing the nanoscopic point of a specialized needle over bumps on a surface. In a First, Scientists See How Water Stores Extra Protons 2022-11-23T05:00:00Z Electronic scanning of either the objective or the sample is used in scanning microscopy. College Physics for AP Courses 2015-08-12T00:00:00Z Two parameters that are important in microscopy are magnification and resolving power. Biology for AP Courses 2022-06-09T00:00:00Z In experiment after experiment using Western blots, microscopy, and other techniques, serious anomalies emerged. Potential fabrication in research images threatens key theory of Alzheimer’s disease 2022-07-20T04:00:00Z Watch the movie entitled “DIC microscopy of cell division in a newt lung cell” and identify the phases of mitosis. Concepts of Biology 2013-04-25T00:00:00Z The team then used cutting-edge microscopy techniques to image how this viral transfer occurred. COVID Virus May Tunnel through Nanotubes from Nose to Brain 2022-07-20T04:00:00Z Physics research underpins the advancement of developments in microscopy. College Physics for AP Courses 2015-08-12T00:00:00Z A light microscope reveals the internal structures of a cell, which cannot be viewed by transmission electron microscopy. Biology for AP Courses 2022-06-09T00:00:00Z Transmission and scanning electron microscopy are both tools to examine biological structures. Miller & Levine Biology 2018-01-01T00:00:00Z Electron microscopy has shown that ribosomes consist of large and small subunits. Concepts of Biology 2013-04-25T00:00:00Z In her lab in Amsterdam, she uses tools such as microscopy and fluorescence to reveal how nutrients flow through mycelial networks. ‘Myconauts’ aim to reveal the often hidden soil fungi that shape ecosystems 2022-07-06T04:00:00Z Another difficulty in microscopy is the fact that many microscopic objects do not absorb much of the light passing through them. College Physics for AP Courses 2015-08-12T00:00:00Z The surface structure of virions can be observed by both scanning and transmission electron microscopy, whereas the internal structures of the virus can only be observed in images from a transmission electron microscope. Biology for AP Courses 2022-06-09T00:00:00Z How do the final images of transmission and scanning electron microscopy differ? Miller & Levine Biology 2018-01-01T00:00:00Z The NVs will absorb and emit light of specific wavelengths, so the track can be spotted clearly with fluorescence microscopy. To crack the mystery of dark matter, physicists turn to supersensitive quantum sensors 2022-04-27T04:00:00Z "I would have preferred that we look at data with a standardized protocol and exclude any confounding factors like poor microscopy or analytical method," said Ringwald. Drug-resistant malaria is emerging in Africa. Is the world ready? 2022-01-30T05:00:00Z Apart from the UV microscope, the variations of microscopy discussed so far in this section are available as attachments to fairly standard microscopes or as slight variations. College Physics for AP Courses 2015-08-12T00:00:00Z Figure 29.33 The body contains three types of muscle tissue: skeletal muscle, smooth muscle, and cardiac muscle, visualized here using light microscopy. Biology for AP Courses 2022-06-09T00:00:00Z “It’s not an onerous task of microscopy and chemistry,” Lendemer said. Your garden isn’t winding down: It’s still lichen season 2021-11-22T05:00:00Z Jan Orenstein, 79, an emeritus professor of pathology and research at George Washington University who also directed the diagnostic research electron microscopy laboratory, died Sept. 12 at a hospital in Washington. Community deaths 2021-11-15T05:00:00Z He studied zoology at Bangor University and earned a Ph.D. in infectious diseases at the University of East London with a thesis on electron microscopy of a parasite that caused an intestinal disease in chickens. ‘We’ve done nothing wrong.’ EcoHealth leader fights charges that his research helped spark COVID-19 2021-11-16T05:00:00Z Confocal microscopy enhances images over conventional optical microscopy, especially for thicker specimens, and so has become quite popular. College Physics for AP Courses 2015-08-12T00:00:00Z In this micrograph, they are visualized using differential interference contrast microscopy, a light microscopy technique that enhances the contrast of the sample. Biology for AP Courses 2022-06-09T00:00:00Z The researchers then used X-ray imaging and electron microscopy to study one of these cell types, which they called secretory neuroid cells. Sponge Cells Hint at Origins of Nervous System 2021-11-09T05:00:00Z But the team used imaging software and scanning electron microscopy to analyze these lustrous chunks, about the height of a quarter and several times as wide. Antarctica Was Once a Land of Fire and Not Ice 2021-11-07T04:00:00Z Researchers cut the fly brain into slabs and then used a technique known as focused-ion beam scanning electron microscopy to image them, layer by painstaking layer. How to Map a Fly Brain in 20 Million Easy Steps 2021-10-26T04:00:00Z The ultimate in microscopy is the electron microscope—to be discussed later. College Physics for AP Courses 2015-08-12T00:00:00Z Ibrahim Cissé, 38, Pasadena, California, 38, cellular biophysicist developing microscopy tools to investigate the subcellular processes underlying genetic regulation and misfunction. 25 MacArthur fellows awarded $625,000 in ‘genius grants’ 2021-09-28T04:00:00Z To get a close-up of arthropod “tools” such as ant mandibles, researchers mapped their atomic makeup using a microscopy technique called atom probe tomography. News at a glance: Mars rock sample, COVID-19 mask wearing, and Ida’s reprieve for labs 2021-09-08T04:00:00Z The hat was then tested extensively using various methods, including electronic microscopy. Newly discovered Napoleon hat with DNA previews in Hong Kong 2021-09-06T04:00:00Z Data from x-ray crystallography and cryo–electron microscopy experiments can be difficult to interpret, Baek and others say, and having a model can help. New public database of AI-predicted protein structures could transform biology 2021-07-22T04:00:00Z They are using electron microscopy to examine tissues for telltale damage, for example, and employing a battery of tests to detect suspect microbes, viruses, parasites, and chemical pollutants. Songbirds are mysteriously dying across the eastern U.S. Scientists are scrambling to find out why 2021-07-06T04:00:00Z This marks an important advancement in the world of electron microscopy. See the Highest-Resolution Atomic Image Ever Captured 2021-06-28T04:00:00Z For this video, Kristiansen visualized his own blood cells with a microscopy technique called dark-field illumination—which is why the cells appear goldenish on a black background rather than red on a white background. Watch Blood Cells Stream Around an Air Bubble. It’s Very Soothing. 2021-04-23T04:00:00Z Cryogenic electron microscopy, or cryo-EM, is a technique that allows scientists to view proteins frozen in a thin layer of ice, bypassing the need for crystallization. They spent 12 years solving a puzzle. It yielded the first COVID-19 vaccines. 2020-12-31T05:00:00Z Taped to the wall was an elaborate map of the brain indicating the regions most desirable for single-cell RNA sequencing and electron microscopy. In Life, She Defied Alzheimer’s. In Death, Her Brain May Show How. 2020-12-11T05:00:00Z Patel’s boss, Smith, next enlisted Ward to verify the protein’s structure and stability with electron microscopy. Will a small, long-shot U.S. company end up producing the best coronavirus vaccine? 2020-11-03T05:00:00Z At least, that’s how I felt when combing through the winning images of the 46th annual Nikon Small World microscopy competition. Perspective | See some of the beautiful winning images of this year’s Nikon Small World photography contest 2020-10-21T04:00:00Z In his work, Jason Kirk of the Baylor College of Medicine uses such cells to benchmark the performance of his microscopy equipment. Luminous Zebra Fish Wins Contest for Microscopic Photography 2020-10-15T04:00:00Z We can do cryoelectron microscopy to probe virus structures and simulate molecule-by-molecule interactions in a matter of weeks—something that used to take years. Lessons from AIDS for the COVID-19 Pandemic 2020-09-29T04:00:00Z Haag’s team used a microscopy technique that digitally reconstructs sections of charcoal from irregular lumps to create images from which the wood can be identified. Unsustainable charcoal, COVID spreads on plane and antibody cocktails 2020-09-22T04:00:00Z The researchers harnessed developments in microscopy that are transforming attempts to probe the opaque, multimillion-dollar international charcoal business. Microscopy illuminates charcoal’s sketchy origins 2020-09-17T04:00:00Z “My background is actually in biophysics and microscopy, so I find a lot of inspiration in these beautiful structures and tissues and formations in nature that are kind of invisible to us,” he said. Wisconsin’s effigy mounds connected people to spirits 2020-09-05T04:00:00Z “The various installations were created from fluorescent microscopy images representing the visual system of the fruit fly brain,” Simard wrote in her statement. The Beautiful Things inside Your Head: Winners of the 10th Annual Art of Neuroscience Contest 2020-07-23T04:00:00Z The scientists studied skin under extremely high resolution using electron microscopy. Goosebumps may be a side effect of hair follicle muscles, scientists say 2020-07-22T04:00:00Z However, the measurements available at the time of this model building were from negative-stain electron microscopy, which does not resolve detail as finely as cryo-EM. How I Built a 3-D Model of the Coronavirus for Scientific American 2020-06-25T04:00:00Z Transmission electron microscopy is the high-tech equivalent of holding something up to sunlight to see what is inside. We may have found life on Mars 24 years ago 2020-06-13T04:00:00Z The cryo-electron microscopy breakthrough, reported by two laboratories late last month, will ultimately help researchers to understand how proteins work in health and disease, and will lead to better drugs with fewer side effects. Daily briefing: The risks of crowd-control weapons 2020-06-03T04:00:00Z The whale’s retina was imaged using scanning electron microscopy. The Beautiful Things inside Your Head: Winners of the 10th Annual Art of Neuroscience Contest 2020-07-23T04:00:00Z A game-changing technique for imaging molecules known as cryo-electron microscopy has produced its sharpest pictures yet — and, for the first time, discerned individual atoms in a protein. Cryo-EM used to visualize individual atoms for first time 2020-06-02T04:00:00Z The scientists uncovered this using deep sequencing and fluorescence microscopy. The animal that lives without oxygen 2020-05-12T04:00:00Z Almeida mastered electron microscopy as a lab technician and went on to a PhD programme and storied career. Daily briefing: Meet the unsung virologist who discovered the first coronavirus 2020-04-15T04:00:00Z Fischer and others in microscopy lab work closely with specially trained artists who colorize the images in ways that help scientists identify crucial elements on the interaction between the virus and cells. Montana lab researchers reveal ‘invisible enemy’ 2020-04-12T04:00:00Z Their new understanding was made possible by modern analytic techniques such as scanning electron and x-ray microscopy and CT scans, says study co-author Laura Matloff, a mechanical engineer at Stanford. Winged “PigeonBot” Flies with Real Feathers 2020-04-10T04:00:00Z Looking at the teeth using polarised light microscopy, the team found the interaction of the cementum with light was not the same throughout the tissue. Teeth reveal past stresses such as menopause and imprisonment 2020-03-25T04:00:00Z Subsequently, they tagged Lge1 and Bre1 with fluorescent protein fragments to visualize interactions between the two proteins in cells using microscopy. Chromatin modified in a molecular reaction chamber 2020-03-10T04:00:00Z Scientists led by UW’s David Baker predicted the structure of this antigen from the virus’s genome, and scientists at the University of Texas, Austin, and NIH confirmed it with a Nobel-winning form of electron microscopy. Synthetic Biologists Think They Can Develop a Better Coronavirus Vaccine Than Nature Could 2020-03-09T04:00:00Z In general, microscopy offers researchers a chance to see how a pathogen - whether it be a virus or bacterium - interacts with a human cell. Montana lab researchers reveal ‘invisible enemy’ 2020-04-12T04:00:00Z Intravital microscopy, which reveals the movements of cells within the body, suggests the lives of these immune cells are eventful. New drugs aim to disarm the immune system’s ‘atomic bomb’ cells 2020-03-05T05:00:00Z “I see every single person working with biological materials,” she says, from engineers developing microscopy techniques to researchers studying pollution in the nearby Great Lakes. Behind the scenes in the biosafety office 2020-03-03T05:00:00Z Next, using a very detailed microscopy technique called cryogenic electron microscopy, the group created a 3D “map,” or “blueprint,” of the spike proteins. Researchers Map Structure of Coronavirus “Spike” Protein 2020-02-21T05:00:00Z Remarkably, the authors were then able to form a stable complex of GPR52 with a modified Gs protein in the absence of an agonist, and to obtain the structure of the complex using cryo-electron microscopy. A self-activating orphan receptor 2020-02-18T05:00:00Z “The virus is a very small part of a cell,” said RML’s Research Technologies Branch interim chief Beth Fischer, who leads the laboratories’ microscopy unit. Montana lab researchers reveal ‘invisible enemy’ 2020-04-12T04:00:00Z Conservators used a variety of tools, including X-ray, infrared and electron microscopy, to bolster the case that it was the work of one of the most important and revered artists in history. Museum’s Rembrandt knockoff turns out to be the real thing 2020-02-17T05:00:00Z Labs around the world are increasingly using a revolutionary technique known as cryo-electron microscopy, or cryo-EM, to determine the 3D shape of proteins. Daily briefing: The potential for repurposing existing drugs to fight COVID-19 coronavirus 2020-02-11T05:00:00Z The virus SH1, reconstructed from images obtained using cryogenic electron microscopy.Credit: Technologies to watch in 2020 2020-01-20T05:00:00Z The viruses are nearly identical in morphology under electron microscopy. Mystery virus found in Wuhan resembles bat viruses but not SARS, Chinese scientist says 2020-01-10T05:00:00Z This microscopy image shows the scars on a pig’s heart caused by an induced heart attack. Daily briefing: Biologists, here’s how to talk to physicists (and vice versa) 2020-01-07T05:00:00Z This difference could be seen by producing other surfaces, or by looking at steps on a surface using scanning tunnelling microscopy. Magnetic and topological order united in a crystal 2019-12-17T05:00:00Z Advanced microscopy is revolutionizing the ways in which we observe the functioning brain. Brain states behind exploring and hunting revealed 2019-12-17T05:00:00Z The digital replicas were produced using focus variation microscopy, a technique that uses images taken at different focal distances using a microscope to create a 3-D rendering. Microscopy imaging techniques render in 3-D the infamous bullet in JFK assassination 2019-12-13T05:00:00Z In addition, it would be valuable to visualize the aggregates in vivo, perhaps using electron microscopy, to obtain a clear picture of what a macrophage–platelet aggregate really looks like. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z In these approaches, one glues a fly to a custom plate that allows one to carefully remove the cuticle over the brain and measure neural activity via electrodes or fluorescence microscopy. Could Fruit Flies Reveal the Hidden Mechanisms of the Mind? 2019-12-03T05:00:00Z Given that fibroblasts regulate the extracellular matrix, the authors used microscopy to visualize physical features of fibres of the protein collagen, which is a component of the extracellular matrix. Ready-made cellular plugs heal skin wounds 2019-11-26T05:00:00Z The specifics of each microscopy technique vary hugely, as do the subsets of scientists that favour them. The microscopic advances that are opening big opportunities in cell biology 2019-11-26T05:00:00Z The team also used confocal microscopy, a technique that allows for higher resolution images of certain sections of the artifacts. Microscopy imaging techniques render in 3-D the infamous bullet in JFK assassination 2019-12-13T05:00:00Z Long-term functional imaging of an entire Drosophila embryo, captured using light-sheet microscopy.Credit: The microscope makers putting ever-larger biological samples under the spotlight 2019-11-25T05:00:00Z The cryo-electron microscope, first announced in Nature19, allowed electron microscopy to be applied to organisms by freezing and suspending them in an aqueous solution. 150 years of scientific illustration 2019-11-04T05:00:00Z The team built the platform using off-the-shelf and 3D-printed components, and set up an automated monitoring system using microscopy and computational image analysis. Microbial chemistry gains fresh focus 2019-09-23T04:00:00Z Fluorescence microscopy, in which florescent molecules are used to light up target proteins, cells or cellular components, allows biologists to observe live samples in real time. The microscopic advances that are opening big opportunities in cell biology 2019-11-26T05:00:00Z This imaging method is called DNA microscopy, for its use of DNA sequencing.Credit: Starfish enterprise: finding RNA patterns in single cells 2019-08-18T04:00:00Z The system can also be applied to another rapidly growing area of microscopy: the imaging of large, ‘cleared’ tissues, such as mouse brains, that have been made transparent through chemical treatment. The microscope makers putting ever-larger biological samples under the spotlight 2019-11-25T05:00:00Z Researchers used a live-cell imaging technique called stimulated emission depletion microscopy, developed by Nobel laureate Stefan Hell, to image the mitochondria, applying a special fluorescent marker molecule to their samples to see them. A Flash on Jupiter, the Death of Mitochondria and the World under Your Skin: The Week’s Best Science GIFs 2019-08-16T04:00:00Z Using a live-cell imaging microscopy approach and experimental methods supported by mathematical modelling, the authors reveal that there are two distinct regions of the endoderm that differ in their internalization mechanism. Genetics and mechanics combine to guide the embryonic gut 2019-08-13T04:00:00Z Burgdorfer’s unique expertise was studying how microbial agents were adapted to the internal tissues of their tick hosts, using experimental infections and microscopy. No, Lyme disease is not an escaped military bioweapon, despite what conspiracy theorists say 2019-08-03T04:00:00Z These techniques use mostly fluorescence microscopy and DNA sequencing to reveal the presence and abundance of RNA molecules in cells within the tissues themselves. Starfish enterprise: finding RNA patterns in single cells 2019-08-18T04:00:00Z At Columbia University in New York City, biomedical engineer Elizabeth Hillman has worked out a way to apply light-sheet microscopy to opaque samples. The microscope makers putting ever-larger biological samples under the spotlight 2019-11-25T05:00:00Z Studying sheets of abdominal tissue donated from seven middle-aged surgical patients, the scientists used a technique called multiphoton microscopy to image deep into the samples. A Flash on Jupiter, the Death of Mitochondria and the World under Your Skin: The Week’s Best Science GIFs 2019-08-16T04:00:00Z Low- and high-resolution microscopy images were taken of these sections, revealing the anatomy of a typical section, including the neuronal processes and synaptic connections. Neural networks mapped in both sexes of the worm 2019-07-02T04:00:00Z To this end, they developed a holographic method that depends on a different principle from that used in conventional electron microscopy: the modulation of quantum interference between electrons by oscillating light fields. Holograms from electrons scattered by light 2019-07-02T04:00:00Z Blending molecular and computational techniques, DNA microscopy infers each molecule’s position on the basis of its neighbours, like creating a map of the United States using the coverage of radio-station transmitters. Starfish enterprise: finding RNA patterns in single cells 2019-08-18T04:00:00Z In biological microscopy, he says, researchers can either look at big samples at low resolution, or small samples at high resolution. The microscope makers putting ever-larger biological samples under the spotlight 2019-11-25T05:00:00Z But Malone-Lee acknowledges that, as with the DNA and broth methods, microscopy is not a perfect solution. ‘I’ve gained my life back’: New tests may help those with persistent urinary tract infections 2019-06-28T04:00:00Z The study analyzed some of the oldest known Martian minerals, looking at zircon and baddeleyite grains seen in Martian meteorites, utilizing electron microscopy and atom probe tomography. Mars may have hosted life earlier than Earth did, study says 2019-06-26T04:00:00Z The ability to use electrons to transport optical phase information potentially opens up a variety of applications in electron microscopy and beyond. Holograms from electrons scattered by light 2019-07-02T04:00:00Z “DNA microscopy is an ingenious approach,” says geneticist Howard Chang of the Stanford University School of Medicine in Palo Alto, California, who wasn’t connected to the research. Researchers use DNA to take pictures of cells 2019-06-20T04:00:00Z As these and other designs percolate through the microscopy community, new research avenues will open. The microscope makers putting ever-larger biological samples under the spotlight 2019-11-25T05:00:00Z The lab examined them “by transmitted and incident light microscopy” that included “root structure, medullary structure and cuticle thickness in addition to scale casts,” wrote Cochran. Oh, deer: Documents reveal FBI once tested hair an Oregon man thought was from Bigfoot 2019-06-05T04:00:00Z “My career started at the beginning of digital microscopy,” Hof says. Can We Live Longer but Stay Younger? 2019-05-13T04:00:00Z Characterizing the structure was challenging, but the researchers ultimately succeeded in visualizing it in atomic detail using cryo-electron microscopy. Protein assembles into Archimedean geometry 2019-05-07T04:00:00Z The image created with DNA microscopy was not as sharp as one the researchers obtained with a light microscope, but it distinguished the genetically distinct red and green cells, the team reports today in Cell. Researchers use DNA to take pictures of cells 2019-06-20T04:00:00Z IBM components in New York and California, for instance, got more than $103 million for “using high-resolution scanning tunneling microscopy to explore the use of atomic spins on surfaces as quantum bits.” Fortune 100 companies’ research funded by taxpayers, OpenTheBooks report finds 2019-05-06T04:00:00Z At probe sizes 25 micrometers and below, microscopy showed virtually no tearing of blood vessels. Slender, neuron-size probes aim for better recordings of brain’s electrical chatter 2019-05-01T04:00:00Z In a large common lab outside the microscopy rooms, there are shelves holding rows of what look like hinged, dark-wooden cigar boxes. Can We Live Longer but Stay Younger? 2019-05-13T04:00:00Z To complete the picture, Das et al. used a technique known as four-dimensional scanning transmission electron microscopy to probe the swirling in-plane dipoles around the equator of a bubble that determine the bubble’s chirality. Electrifying skyrmion bubbles 2019-04-16T04:00:00Z For instance, optical microscopy often can’t distinguish among cells with DNA differences, such as tumor cells with specific mutations or immune cells, which are often genetically unique after shuffling their DNA. Researchers use DNA to take pictures of cells 2019-06-20T04:00:00Z The resolution of standard optical microscopy is limited to a few hundreds of nanometres, which is much too low to observe ångström-scale atomic motion. Snapshots of vibrating molecules 2019-04-02T04:00:00Z That allowed the use of intricate brain-recording techniques — such as electrical recordings from inside neurons, or optical microscopy to image large numbers of neurons. The mouse in the video game 2019-03-11T04:00:00Z S.W.’s account, @pondlife_pondlife, for example, is currently exhibiting images of microbial life at the Brooklyn Botanic Garden, and works with several educational organizations throughout New York City, running workshops on microscopy. How we use Instagram to communicate microbiology to the public 2019-02-03T05:00:00Z In his research, he used X-ray fluorescence, microscopy and ultraviolet imaging to study the drawings. Leonardo da Vinci's thumbprint discovered: Drawing in Queen Elizabeth's collection reveals secrets 2019-01-29T05:00:00Z Given that, plus structural differences revealed by electron microscopy analysis, it’s likely that Anchiornis feathers weren’t suitable for flight, Schweitzer says, but represent an intermediate stage in the evolution toward flight feathers. Fossil feathers reveal how dinosaurs took flight 2019-01-28T05:00:00Z Super-resolution microscopy is bringing chromatin — a 3D complex of DNA and protein — into focus.Credit: Technologies to watch in 2019 2019-01-22T05:00:00Z Expansion microscopy allows scientists to label individual neurons and trace their thinnest tendrils to chart their connections. Top stories: last wild caribou in the lower 48, glowing brains, and ancient fossils under threat 2019-01-18T05:00:00Z “This technique, known as expansion microscopy, involves embedding tissue into a hydrogel and then expanding it, allowing for high-resolution imaging with a regular microscope,” explained MIT in the statement. MIT develops incredible system to 'shrink' objects 2018-12-14T05:00:00Z The group said the more sensitive electron microscopy was impractical. Special Report: J&J knew for decades that asbestos lurked in its... 2018-12-14T05:00:00Z The payments were part of a deal in which scientists at South Korean universities were guaranteed access to one of LBNL’s imaging facilities, an X-ray microscopy beamline. South Korean scientists protest treatment of university president accused of misusing funds 2018-12-12T05:00:00Z Using scanning electron microscopy to produce photos like the one above, the team discovered blade-shaped mandible hooks with backward-pointing teeth—all the better to pierce into soft-bodied bugs in the soil where these larvae live. Assassin fly babies have 'Swiss army knife' mouths 2018-12-07T05:00:00Z Conventional light microscopes are unable to distinguish molecules separated by less than the ‘diffraction limit’ of light, around 200 nanometres — a problem that led to the development of technically sophisticated super-resolution microscopy approaches. Transparent tissues bring cells into focus for microscopy 2018-12-03T05:00:00Z Similar to their research on expansion microscopy, the researchers used a highly absorbent material made of polyacrylate, which is commonly found in diapers, as the “scaffold” for their nanofabrication process. MIT develops incredible system to 'shrink' objects 2018-12-14T05:00:00Z And the talc samples that were subjected to the most sensitive electron microscopy test were a tiny fraction of what was sold. Special Report: J&J knew for decades that asbestos lurked in its... 2018-12-14T05:00:00Z In 1968, Dr. Klug and his collaborators announced the technique of Fourier electron microscopy, showing how seemingly limited data could permit three-dimensional molecular reconstructions. Aaron Klug, Nobel-winning scientist who examined crystal structure, dies at 92 2018-11-24T05:00:00Z Ordinary electron microscopy is “like flying propeller planes”, says applied physicist David Muller. Daily briefing: Decolonizing Mars 2018-11-20T05:00:00Z In their first-generation ‘expansion microscopy’ method5, published in 2015, samples are treated with specially designed fluorescent labels recognizing target molecules of interest, and then incubated with a polymer solution that forms a hydrogel matrix. Transparent tissues bring cells into focus for microscopy 2018-12-03T05:00:00Z Ordinary electron microscopy is “like flying propeller planes”, Muller says. The microscope revolution that’s sweeping through materials science 2018-11-20T05:00:00Z The result is a mix of fascinating findings at all scales, from scanning electron microscopy displaying the exquisite geometry of enamel prisms, to toothpick use among hominins some 2 million years ago. Ethics at the cutting edge, beastly movers and shakers, and teeth as time machines: Books in brief. 2018-11-12T05:00:00Z Among the major contributions made by Dr. Klug and co-workers was to break down a substance called chromatin into fragments susceptible to study with diffracted X-rays and the beams of electron microscopy. Aaron Klug, Nobel-winning scientist who examined crystal structure, dies at 92 2018-11-24T05:00:00Z They used methods such as calcium imaging, mass spectrometry, immunohistochemistry, electron microscopy and RNA sequencing to probe cellular function, morphology and molecular features3. Tapping into the brain’s star power 2018-10-30T04:00:00Z The book opens and closes with a supreme exemplar of a lay scientist: seventeenth-century Dutch businessman Antonie van Leeuwenhoek, who pioneered microscopy and discovered bacteria and protozoa, opening up the universe of microbiology. There’s a jungle in your bed 2018-10-28T04:00:00Z In a phone interview, Nipam Patel, director of the Marine Biological Laboratory, said the laureates’ work ushered in a revolution in microscopy and biological imaging. Osamu Shimomura, atomic blast survivor and Nobel-winning chemist, dies at 90 2018-10-23T04:00:00Z Science mega-prize The inventor of a revolutionary, high-resolution microscopy technique was one of six big winners of this year’s Breakthrough prizes, announced on 17 October. Medical chimps’ retirement, Nobel laureates’ Brexit warning and science mega-prizes 2018-10-23T04:00:00Z "The Tales Teeth Tell" builds on centuries of scholarship, both in the areas of paleoanthropology — the study of human origins and evolution - and microscopy. The history of humanity is written across your smile 2018-10-21T04:00:00Z Biophysicist Xiaowei Zhuang was the lead inventor of a microscopy technique that was one of the first to break a fundamental resolution limit of conventional light microscopes. Daily briefing: Top institutions get more grants (but deliver much less for the money) 2018-10-17T04:00:00Z She was awarded one of four prizes in the life sciences for developing stochastic optical-reconstruction microscopy—known as STORM—just over a decade ago. Revolutionary Microscopy Technique Nets Most Lucrative Prize in Science 2018-10-17T04:00:00Z She was awarded one of four prizes in the life sciences for developing stochastic optical-reconstruction microscopy — known as STORM1 — just over a decade ago. Revolutionary microscopy technique nets most lucrative prize in science 2018-10-16T04:00:00Z The technique was one of the first to break a fundamental resolution limit of conventional light microscopy, and is now used widely by biologists to reveal the hidden molecular structures of cells. Medical chimps’ retirement, Nobel laureates’ Brexit warning and science mega-prizes 2018-10-23T04:00:00Z Smith’s explanations, along with her genuine enthusiasm for microscopy, work to counter this perception. The history of humanity is written across your smile 2018-10-21T04:00:00Z Known as cryo-electron microscopy, it allowed biomolecules to be visualised in their natural state for the first time, triggering a “revolution in biochemistry”, the Nobel committee said at the time. Nobel prize in chemistry 2018 – live 2018-10-03T04:00:00Z He subjected those samples to electronic microscopy analysis to determine exactly what type of element was emitting radiation. Hidden danger: Radioactive dust is found in communities around nuclear weapons sites - Los Angeles Times 2018-09-28T04:00:00Z “Zhuang contributed several results that really got the super-resolution revolution started in biological microscopy.” Revolutionary microscopy technique nets most lucrative prize in science 2018-10-16T04:00:00Z Better validation tools and practices are not the only thing holding back cryo-electron microscopy; many researchers are unable to produce images of sufficient quality to even start the process. Cryo-electron microscopy shapes up 2018-09-24T04:00:00Z Today, conservation scientists use advanced analytical techniques like microscopy or spectroscopy to identify materials. These Cultural Treasures Are Made of Plastic. Now They’re Falling Apart. 2018-08-28T04:00:00Z In the new study published this month in Geophysical Research Letters, the team used a technique called electron force microscopy to create visual images of carbon-containing molecules. First "Photos" of Ocean Carbon Molecules Hold Clues to Future Warming 2018-08-08T04:00:00Z Using imaging tools such as piezoresponse force microscopy, the authors observed a polarization perpendicular to the plane of the film that is stable at temperatures of up to 700 kelvin. Stable and switchable electric polarization in two dimensions 2018-07-29T04:00:00Z Using low-energy electrons for microscopy is good because it greatly reduces the damage inflicted on the specimen by the electrons. A record-breaking microscope 2018-07-17T04:00:00Z The team used electron microscopy, a technique that sends beams of electrons through a particle, projecting an image. High-Resolution Snapshot of Zika Virus Reveals Clues to Fighting It 2018-06-26T04:00:00Z Kaltofen used an unusual technique that involves both electron microscopy and a specialized X-ray analysis that can detect extremely low levels of radioactive particles. Study: Traces of radioactive contamination found in homes of six Hanford workers 2018-06-14T04:00:00Z Shoshkes-Carmel et al. performed high-resolution microscopy, which revealed that these cells are telocytes — thin cells with long protrusions called telopodes, which form a 3D network underlying the epithelial cells throughout the gut. Debate over the identity of an intestinal niche-cell population settled 2018-06-05T04:00:00Z This was the first time that these specimens were subject to electron microscopy and chemical analysis. Dandruff reveals how dinos shed their skin 2018-05-25T04:00:00Z However, light-sheet fluorescence microscopy is a technology particularly suited to imaging large volumes quickly and without causing any damage. Bendy Laser Beams Can Examine Human Tissue Like Never Before 2018-05-23T04:00:00Z The chemical structure of a molecule resolved by atomic force microscopy. The effect of hydration number on the interfacial transport of sodium ions 2018-05-13T04:00:00Z With microscopy techniques, the group examined the structures further and determined that they are open channels through which organelles and membrane vesicles move from one cell to another. Cells Talk and Help One Another via Tiny Tube Networks 2018-05-07T04:00:00Z L.Z. conducted the majority of the experiments and performed light microscopy analysis. Hyperexpandable, self-healing macromolecular crystals with integrated polymer networks 2018-05-01T04:00:00Z In February, he and his team at Salk won a $1.2 million award from the W. M. Keck Foundation to develop living mammalian tissues that are transparent to light microscopy. Famed cancer biologist allegedly sexually harassed women for decades 2018-04-26T04:00:00Z The geometry for this form of microscopy was originally developed at the start of the 20th century to aid the study of nanoparticles. Bendy Laser Beams Can Examine Human Tissue Like Never Before 2018-05-23T04:00:00Z The electric field of CO tips and its relevance for atomic force microscopy. The effect of hydration number on the interfacial transport of sodium ions 2018-05-13T04:00:00Z Useful answers are emerging, however, because the budding field of TNT research is benefiting from advances in microscopy and other techniques. Cells Talk and Help One Another via Tiny Tube Networks 2018-05-07T04:00:00Z Protein concentrations were determined using the Bradford assay. d, Confocal microscopy images of highly expanded crystal–hydrogel hybrids, showing the structural deterioration of the facets and the edges. Hyperexpandable, self-healing macromolecular crystals with integrated polymer networks 2018-05-01T04:00:00Z The use of SMALPs as a novel membrane protein scaffold for structure study by negative stain electron microscopy. Structure of the alternative complex III in a supercomplex with cytochrome oxidase 2018-04-24T04:00:00Z It was only with the advent of laser illumination and naturally occurring fluorescent biomarkers that light-sheet microscopy, in the past two decades, saw a renaissance in biomedical imaging. Bendy Laser Beams Can Examine Human Tissue Like Never Before 2018-05-23T04:00:00Z Matt, Karsten and I saved space by sharing chemical and microscopy rooms, and saved money by pooling equipment. A lab co-op helps young faculty members to thrive 2018-04-22T04:00:00Z “Being able to see what you study, to me, is just the main driving force for why I’ve always been interested in microscopy,” Smith said. Cells Talk and Help One Another via Tiny Tube Networks 2018-05-07T04:00:00Z A ferritin crystal infused with polymer precursors was placed on a microscopic ruler and imaged by light microscopy. Hyperexpandable, self-healing macromolecular crystals with integrated polymer networks 2018-05-01T04:00:00Z Using high-definition microscopy, the researchers measured the composition of diamonds locked up in rocks left scattered in the Nubian desert of northern Sudan after the asteroid 2008 TC3 hit the atmosphere. Space diamonds 'came from lost planet' 2018-04-17T04:00:00Z The same problem applies to trying to see inside large samples using fluorescence microscopy. Bendy Laser Beams Can Examine Human Tissue Like Never Before 2018-05-23T04:00:00Z Routinely-used malaria diagnosis tools such as microscopy and genetic tests such as polymerase chain reaction may not be able to distinguish between the two species, she says. Rare human outbreak of monkey malaria detected in Malaysia 2018-04-15T04:00:00Z Repeatable target localization for long-term in vivo imaging of mice with 2-photon microscopy. Innate immune memory in the brain shapes neurological disease hallmarks 2018-04-10T04:00:00Z Through technologies such as scanning electron microscopy, Scott’s study of fossil charcoal has unearthed an astounding deep-past record of botanical riches and shifts in climate and oxygen levels. The deep past of megafires, big data’s Achilles heel and behind the scenes of the March for Science: Books in brief 2018-04-10T04:00:00Z Images captured by transmission electron microscopy show blobs of collagen bundles and long, snaky cells. Is This Tissue a New Organ? Maybe. A Conduit for Cancer? It Seems Likely. 2018-03-31T04:00:00Z In light-sheet microscopy, a thin sheet of light is sent into the side of the sample which slices right across the part you want to look at. Bendy Laser Beams Can Examine Human Tissue Like Never Before 2018-05-23T04:00:00Z Electron microscopy and computer modelling revealed that analogue 2 probably binds to phospholipid molecules in the bacterial membrane, resulting in membrane distortion that might help to kill the bacteria. Bacterial persister cells tackled 2018-03-27T04:00:00Z Scanning confocal optical microscopy and magnetic resonance on single defect centers. Continuous-wave room-temperature diamond maser 2018-03-20T04:00:00Z He recalls feeling both amazement at the finding and uncertainty that atomic force microscopy could really capture such a level of molecular detail. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z Cryo-ET in 3D uses electron microscopy to view very thin, frozen but hydrated sections of a cell from various angles. Protein aggregates caught stalling 2018-03-18T04:00:00Z I exhibited my work here several years ago in a show based on microscopy — viewing objects through a microscope — and cellular structure. Finding Art in the Gut, and Other Unexpected Places 2018-03-02T05:00:00Z Cryogenic electron tomography combines electron microscopy with CT scans. Human Sperm Has a Surprising Tail Shape We've Never Noticed Before 2018-02-22T05:00:00Z The authors’ use of modelling is particularly effective, and gets around the practical difficulties of directly observing mechanochemical reactions at atomic resolution using microscopy. Molecules pressured to react 2018-02-20T05:00:00Z Although atomic force microscopy can now image structures at atomic resolution, researchers had to overcome several hurdles to make this feasible in practice. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z The tracts were fused with a green fluorescent protein that enabled their precise position to be determined using correlative light microscopy. Protein aggregates caught stalling 2018-03-18T04:00:00Z In the nematocysts seen under microscopy, the ridges were spaced at two different intervals. Marine Microbes Exchange Fire With Elaborate Subcellular Weapons [Video] 2018-02-11T05:00:00Z These included a new type of microscopy to better view the cells during handling to using several compounds that encourage cell reprogramming, which hadn't been tried before on primates, they report today in Cell. These monkey twins are the first primate clones made by the method that developed Dolly 2018-01-24T05:00:00Z The team at the Institute of Cancer Research used a technique called cryo-electron microscopy, which won the 2017 Nobel Prize for chemistry for revolutionising biochemistry. Chemistry 'Van Gogh' could help with cancer 2018-01-17T05:00:00Z To resolve these problems, scientists at IBM Research in Zürich, Switzerland, borrowed from previous work on scanning tunnelling microscopy. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z The researchers next examined the axons with electron microscopy. Do Brain-Wiring Differences Make Women More Vulnerable to Concussions? 2017-12-15T05:00:00Z Microrheology of human lung epithelial cells measured by atomic force microscopy. Force loading explains spatial sensing of ligands by cells 2017-12-05T05:00:00Z Outcome of the first electron microscopy validation task force meeting. Structural basis for the initiation of eukaryotic transcription-coupled DNA repair 2017-11-21T05:00:00Z We thank members of the Kenyon laboratory and our colleagues at Calico for discussions and comments on the manuscript, and the Calico microscopy core, especially M. Ingaramo, for help with microscopy and sensors. A lysosomal switch triggers proteostasis renewal in the immortal C. elegans germ lineage 2017-11-21T05:00:00Z Indeed, almost a year to the day on which Qiu’s paper was published online, Liljeroth’s team presented atomic force microscopy images that contained lines connecting atoms that do not interact through hydrogen bonding3. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z Columbia biophysicist Joachim Frank, awarded a Nobel in chemistry for his work in microscopy, said in an email he was “very relieved” when he learned there was no chance of an encounter with the president. Trump, Breaking with Precedent, Won't Meet with American Nobel Recipients 2017-11-13T05:00:00Z Trabuco, L. G., Villa, E., Mitra, K., Frank, J. & Schulten, K. Flexible fitting of atomic structures into electron microscopy maps using molecular dynamics. Structures of transcription pre-initiation complex with TFIIH and Mediator 2017-10-31T04:00:00Z And three pioneers of a technique called cryo–electron microscopy won the Nobel Prize in Chemistry. Top stories: Science Nobels, a giant insect back from the dead, and how Neandertal DNA makes you fat 2017-10-06T04:00:00Z By that time, electron microscopy had advanced and it was possible to see the organism up close. Why can’t we cure the common cold? 2017-10-06T04:00:00Z But Philip Moriarty, a physicist at the University of Nottingham, UK, suggests that this is unlikely to work in all cases, because even experienced researchers disagree on what atomic force microscopy data show. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z U.K. and Switzerland won the Nobel Prize in Chemistry for developments in electron microscopy. Kazuo Ishiguro Wins the 2017 Nobel Prize for Literature 2017-10-05T04:00:00Z To see the structure of molecules at ultrahigh resolution, scientists must hold molecules in place in their natural configuration. Other microscopic techniques, such as X-ray crystallography, are far more rigid than cryo-electron microscopy. Three biophysicists win 2017 Nobel Prize in chemistry for imaging molecules of life 2017-10-04T04:00:00Z The technique, called cryo-electron microscopy, allowed biomolecules to be visualised in their natural configuration for the first time, triggering a “revolution in biochemistry”, according to the Nobel committee. Nobel prize in chemistry awarded for method to visualise biomolecules 2017-10-04T04:00:00Z This is the second chemistry Nobel for microscopy in the past 4 years. Nobel Chemistry Prize Won for Capturing Proteins in Action 2017-10-04T04:00:00Z His team was using a method called atomic force microscopy, dragging an ultrasharp probe across the surface of a sample to reveal its topography at subnanometre resolution. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z The The Royal Swedish Academy of Sciences has produced an easy-to-read history about the role each of the three winners played in the development of cryo-electron microscopy. A cold, clear view of life wins chemistry Nobel 2017-10-04T04:00:00Z Rossmann, a member of the team that recently imaged the Zika virus surface, said that the microscopy field is entering a period of “resolution revolution.” Three biophysicists win 2017 Nobel Prize in chemistry for imaging molecules of life 2017-10-04T04:00:00Z “Cryoelectron microscopy is about to completely transform structural biology,” he said. Cryo-electron microscopy wins chemistry Nobel 2017-10-03T04:00:00Z The three men developed what the Nobel committee described as cryo-electron microscopy for the high-resolution structure determination of biomolecules in solution. Nobel Prize in Chemistry Awarded for Cryo-Electron Microscopy 2017-10-04T04:00:00Z And there lies the challenge of using atomic force microscopy to capture images at subnanometre resolution. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z They developed a technique called cryo-electron microscopy, which simplifies the process for looking at the building blocks of biology. Nobel prize awarded for imaging molecules 2017-10-04T04:00:00Z “Cryo-electron microscopy is about to completely transform structural biology,” said Frank, calling remotely to the Nobel conference on Wednesday. Three biophysicists win 2017 Nobel Prize in chemistry for imaging molecules of life 2017-10-04T04:00:00Z Most microscopy techniques can't get a clear view of these structures in action, even in cultured cells. How the Internet of cells has biologists buzzing 2017-09-19T04:00:00Z “I’m absolutely sure they’re right,” says the retired adjunct professor at The Pennsylvania State University, who helped pioneer the use of 3-D microscopy for bone mark analysis and was not involved in the work. Family Meal? Ancestral Humans May Have Engaged in Ritualistic Cannibalism 2017-08-11T04:00:00Z Similar to atomic force microscopy, the method uses a probe to scan a surface, passing an electrical current through the sample to measure changes in conductivity rather than force. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z Researchers at the Korea Advanced Institute of Science and Technology combined a detailed imaging technique called holographic microscopy with artificial intelligence. AI can now detect anthrax which could help the fight against bioterrorism 2017-08-07T04:00:00Z In the 1990s, Henderson showed that cryo-electron microscopy could be as detailed as X-ray crystallography when he made an atomic model of a membrane protein found in microorganisms. Three biophysicists win 2017 Nobel Prize in chemistry for imaging molecules of life 2017-10-04T04:00:00Z Smith is developing methods to visualize membrane nanotubes using lattice light-sheet microscopy, which monitors planes of light to build up 3D images. How the Internet of cells has biologists buzzing 2017-09-19T04:00:00Z To probe further, Bello and her colleagues examined the remains using two types of microscopy: scanning electron and focus variation microscopy. Family Meal? Ancestral Humans May Have Engaged in Ritualistic Cannibalism 2017-08-11T04:00:00Z Only about 100 known molecules have been resolved to atomic resolution using carbon-monoxide-tip atomic force microscopy, he estimates. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z This is the 20th annual Wellcome Image Awards which celebrates colourful and captivating scientific images - from photography and illustration, to super-resolution microscopy and medical scans. Colourful, creative and close up: Wellcome Images 2017 - BBC News 2017-03-15T04:00:00Z This portfolio of microscopy images was entered as a set in the Beauty of Plants category and features sectioned and stained flower buds. Winning photos of great gardens - BBC News 2017-02-04T05:00:00Z To do so he incorporated electron microscopy, endoscopic fiber optics and custom lenses. Lennart Nilsson, Photographer Who Unveiled the Invisible, Dies at 94 2017-02-01T05:00:00Z “It is quite interdisciplinary and draws from a wide range of techniques and technologies from microscopy to digital imaging,” Lamson said in an email. Issaquah bookbinder among handful at libraries nationwide still operating a ‘mendery’ 2017-01-07T05:00:00Z Recording conventional atomic force microscopy images can take more than a minute. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z “It is quite interdisciplinary,” Ms. Lamson said in an email, “and draws from a wide range of techniques and technologies from microscopy to digital imaging.” He Fixes Cracked Spines, Without an Understudy 2017-01-06T05:00:00Z Electron microscopy is reliable and widely used to view thin sections of materials. Fire up the atom forge 2016-11-21T05:00:00Z An approach known as scanning tunnelling microscopy shed light on the structure of the thin layers of mineralised tissue. Dinosaur brain tissue discovered for first time in 130m-year-old fossil 2016-10-27T04:00:00Z “You turn microscopy from something that is purely observational into something that is interactive,” Riedel-Kruse said. New 3D printed microscope lets kids 'play' microbiology 2016-10-27T04:00:00Z When combined with an automated system that keeps the system level, this enables carbon-monoxide-tip atomic force microscopy that provides “beautiful images”, according to team member Martin Setvin. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z After his Nobel Prize, Zewail's focus shifted towards a new form of microscopy that used ultrafast pulses of electrons to track reactions in space and time at the atomic scale. Ahmed Hassan Zewail (1946-2016) : Nature : Nature Research 2016-09-06T04:00:00Z Electron microscopy is on the brink of a transition. Fire up the atom forge 2016-11-21T05:00:00Z Using a specialized microscopy technique, the scientists observed that there was growth in the neurons along that pathway. Turning off this newly discovered brain pathway could help us block fearful memories 2016-09-05T04:00:00Z Their method also shrinks bodies by up to 65%, making it possible to image whole animals using a technique called light-sheet microscopy. Floods, fires, Zika and a hidden portrait 2016-08-25T04:00:00Z For a PhD student with little experience of scanning-probe techniques, it can take “a couple of months to start getting very nice atomic force microscopy images”, Liljeroth says. How atomic imaging is being pushed to its limit 2018-03-19T04:00:00Z Using scanning electron microscopy to see the peacock spider’s design up close, researchers discovered that tiny threadlike fibers sandwiched in between two layers of scales coat the spider’s exterior—a design unique to this spider. Video: Peacock spider creates its glowing blue color in an unusual way 2016-08-10T04:00:00Z After winning the Nobel, Dr. Zewail switched gears to invent a new form of microscopy using ultrafast pulses of electrons instead of light. Ahmed H. Zewail, Nobel-Prize-Winning Chemist, Dies at 70 2016-08-05T04:00:00Z He is also credited with developing a new research field dubbed four-dimensional electron microscopy, which helps capture fleeting processes and turn them into a kind of digital film. First Arab Nobel science winner Ahmed Zewail dies - BBC News 2016-08-03T04:00:00Z Then they checked their teeth about 12 weeks later with high-resolution X-rays and microscopy and found that there was more dentin. Could your cavity-filled tooth repair itself with stem cells in the future? 2016-07-05T04:00:00Z The collection features microscopy photographs of cancer-related cells, tissues and molecules from researchers at two dozen of the nation’s leading cancer centers. Deadly and beautiful: The mesmerizing images of cancer research 2016-07-11T04:00:00Z She is excited about using the latest technologies, such as cryo-electron microscopy, which for the first time is allowing researchers to study proteins in fine detail in their native environments, rather than as purified crystals. Science stars of China 2016-06-19T04:00:00Z They were awarded for inventing atomic force microscopy and developing practical uses for it. Nine Scientists Win Kavli Prizes Totaling $3 Million 2016-06-02T04:00:00Z Photograph: University of Athens The team used microscopy and x-rays to study the mineral content and texture of the formations. The lost (microbe) colony: bacteria make underwater 'ruins' off Greek island 2016-06-02T04:00:00Z He became an editor at the journal in 2014, overseeing papers on electron microscopy. Open-access journal eLife gets £25 million boost 2016-05-31T04:00:00Z “In life sciences, there is growing adoption of electron microscopy to study the structure of proteins,” Thermo Fisher president and CEO Marc Casper said in a statement. Thermo Fisher acquires Hillsboro microscope maker for $4.2 billion 2016-05-27T04:00:00Z The cryo-electron microscopy structure shows a virus with a more compact surface. Structure of the thermally stable Zika virus : Nature : Nature Publishing Group 2016-04-18T04:00:00Z Unlike many other forms of microscopy, atomic force microscopy acquires images of samples on the nanoscale by “feeling” them rather than “seeing” them. Nine Scientists Win Kavli Prizes Totaling $3 Million 2016-06-02T04:00:00Z When they sent their samples off for transmission electron microscopy - a method of imaging such small life - at IU’s Electron Microscopy Center, they got an image back of the new phage, OHR. IU Southeast student, professor discover virus in Ohio River 2016-03-27T04:00:00Z His colleagues used electron microscopy to examine changes in the synapses of the hippocampal and prefrontal cortex regions of ageing rhesus monkeys. Ageing: Restoration project : Nature : Nature Publishing Group 2016-03-01T05:00:00Z And in an ideal world, most clinics would use LED microscopy or GeneXpert. The rats who sniff out tuberculosis 2016-02-23T05:00:00Z Ms Giannotti said microscopy images taken under UV light helped to reveal colours and patterns of healthy algal cells, and the spores of infections attacking the tiny plant life. Healthy and diseased marine algae inspire new designs - BBC News 2016-01-22T05:00:00Z The project, eventually known as Molecular Expressions, became a voluminous microscopy reference used by Dr. Waterman and many others. Michael W. Davidson, a Success in Microscopes and Neckwear, Dies at 65 2016-01-12T05:00:00Z Backman and his team have developed a form of microscopy that they say could overcome this difficulty by allowing pathologists to see changes inside cells that are too small to resolve with standard microscopy. Prognosis: Proportionate response : Nature : Nature Publishing Group 2015-12-14T05:00:00Z A technique called light-sheet microscopy illuminates just a thin slice of the embryo at a time, minimizing the living specimen’s exposure. Video: First-of-its-kind movie shows mouse developing from a single cell 2015-12-16T05:00:00Z GeneXpert is especially useful in coinfections of TB and HIV that often are missed on the standard microscopy used by many labs instead of the more intensive culturing. TB community borrowing a page from HIV/AIDS 2015-12-08T05:00:00Z To find out more about the "tarantula blue," researchers used different microscopy techniques to analyze tarantula hairs. Blue tarantulas may help humans make better wide-angle computer displays 2015-11-27T05:00:00Z A few years later, Mr. Davidson returned to Florida State as a microscopy technician for a materials research laboratory. Michael W. Davidson, a Success in Microscopes and Neckwear, Dies at 65 2016-01-12T05:00:00Z “Nice to meet you, sir,” Omalu says, in a microscopy room at the West Virginia University Hospital. The Doctor the NFL Tried to Silence 2015-11-24T05:00:00Z The scientists explored how the eyes are made and how well they work using high-resolution microscopy and x-ray techniques, as well as computer modeling. Video: Sea creature makes a thousand eyes from its shell 2015-11-19T05:00:00Z Near-field microscopy technically beats the diffraction limit, but it is not very practical because it uses a sharp imaging tip that must be extremely close to the sample. Cell imaging: Beyond the limits : Nature : Nature Publishing Group 2015-10-20T04:00:00Z Using electron microscopy to examine the neurons at nanoscale resolution, the group found that wherever synapses had emerged, the PNN's tight-knit lattice had developed holes, as if to accommodate the new connections. Mysterious ‘holes’ in neuron net may help store long-term memories 2015-10-20T04:00:00Z Over the last decade, Mr. Davidson’s research team, housed at Florida State’s National High Magnetic Field Laboratory, or MagLab, helped revolutionize optical microscopy. Michael W. Davidson, a Success in Microscopes and Neckwear, Dies at 65 2016-01-12T05:00:00Z The Royal Society will celebrate the book’s anniversary this Saturday with a microscopy drawing event and an exhibition in London. Hooke opened up the world of the unseen 350 years ago 2015-10-16T04:00:00Z They studied the bones and anatomy of the fetus using scanning electronic microscopy and high-resolution micro-X-ray. Horselike Fossil From 48 Million Years Ago Preserved While Pregnant 2015-10-09T04:00:00Z The method is a form of light microscopy, augmented by fluorescent chemical labels. Cell imaging: Beyond the limits : Nature : Nature Publishing Group 2015-10-20T04:00:00Z Sam Lord, a microscopy specialist at the University of California, San Francisco, who began making predictions on his Everyday Scientist blog in 2008, also picked Charpentier and Doudna for the chemistry prize. Nobel speculation kicks into high gear 2015-09-23T04:00:00Z In a pivotal step, Henderson and Unwin omitted the stain when they used electron microscopy to image crystal sheets of bacteriorhodopsin — instead, they placed the crystals on metallic grids to make the protein stand out. The revolution will not be crystallized: a new method sweeps through structural biology 2015-09-08T04:00:00Z Ms. Ward, for example, celebrates Irish scientist Mary Ward, an expert in microscopy and insects. Look closely: 8 wallpapers that will completely defy your expectations 2015-08-28T04:00:00Z I started reading up on all the developments in microscopy of the past decade. Eric Betzig’s Life Over the Microscope 2015-08-28T04:00:00Z Working on near-field microscopy at renowned research centre Bell Labs in Murray Hill, New Jersey, in the early 1990s, he made advances on a technology called near-field imaging. Cell imaging: Beyond the limits : Nature : Nature Publishing Group 2015-10-20T04:00:00Z As they collected an overwhelming mass of electron microscopy data, the question was how they would ever manage to interpret it all. Why Neuroscience Needs Hackers 2015-08-25T04:00:00Z So the pair decided to try electron microscopy instead. The revolution will not be crystallized: a new method sweeps through structural biology 2015-09-08T04:00:00Z The authors measured the charge at the surface of the vesicles and performed selective fluorescence resonance energy transfer and microscopy studies to probe RNA-membrane association. Origin of Life: First Cells May Have Been Glued Together 2015-08-13T04:00:00Z The researchers genetically modify neurons so that each cell fluoresces when it fires; they then use innovative microscopy that involves firing sheets of light into the brain to record that activity. Fruit-fly brains filmed in action 2015-08-10T04:00:00Z On Jan. 22, in the Natural History museum’s electron microscopy lab, Scott Whittaker focused his powerful microscope on the silver box, the size of a salt shaker, illuminated under the lens. Jamestown excavation unearths four bodies — and a mystery in a small box 2015-07-27T04:00:00Z EWG hired an independent company, Scientific Analytical Institute from Greensboro, N.C., to conduct so-called transmission electron microscopy tests to look for asbestos. Asbestos Found in Kids' Crayons, Toy Kits: Report 2015-07-08T04:00:00Z At the time, electron microscopy was used to study viruses or slices of tissue that had been treated with heavy-metal stains. The revolution will not be crystallized: a new method sweeps through structural biology 2015-09-08T04:00:00Z It is indeed possible to detect both entire viruses and mere molecular bits of them with the aid of either electron microscopy or RNA analysis. Scientists Shoot Down Claim That Alien Life May Be on Comet 2015-07-06T04:00:00Z Delving into the activities of that colleague, Whitehurst’s inquiries led him in due course to the almighty mess caused by hair microscopy. The man who was jailed for 22 years – on the fantasy evidence of a single hair 2015-06-23T04:00:00Z “Right now, my idea is to isolate those individual proteins and then to actually attach them to an empty viral envelope and then observe it using electron cell microscopy,” she explains. Florida Teen Explores Using Proteins to Block Viruses 2015-05-12T04:00:00Z A few scientists were starting to rigorously apply new techniques, such as specialized scanning electron microscopy for mineralogy, but other practitioners continued to use unsophisticated methods to give investigators the answers they wanted, he says. Forensic science: The soil sleuth 2015-04-20T04:00:00Z The other is a microscopy specialist and lab manager. The future of the postdoc 2015-04-06T04:00:00Z The researchers then used electron microscopy to visualize their necklaces, shown above. A necklace fit for a virus 2015-03-27T04:00:00Z Through a technique called atomic force microscopy, he researches the properties of materials. GW opens massive science hall, aiming to rise in college research prominence 2015-03-03T05:00:00Z Cutting-edge techniques, such as high-resolution microscopy, will allow live imaging of chromatin architecture and a means of studying its dynamics in space and time. Epigenomics: Roadmap for regulation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z When high definition telemedicine or microscopy become more prevalent, however, you need to be able to upload a lot of information as well as download it. How Will the Fight over Public ISPs and Net Neutrality Play Out? 2015-02-18T05:00:00Z The mobile microscopy unit uses the phone's camera to visualize and measure the length of single-molecule DNA strands. Quick DNA Scans Could Ensure Food Is Safe to Eat 2015-02-04T05:00:00Z What we’ve done is we’ve redesigned the microscopy workflow to combine the sectioning and the imaging into a single machine in a way that fundamentally allows us to image much faster. Digital Imaging On The Cutting Edge Of Tissue Analysis 2015-01-28T05:00:00Z In the study, published today in Biology Letters, researchers used three different kinds of microscopy techniques to study organs that produce silk in Uloborus plumipes, the garden center spider. This spider combs its tiny silk threads to make them extra sticky 2015-01-27T05:00:00Z The scientists call the new technique expansion microscopy. Expansion Microscopy Stretches Limits of Conventional Microscopes 2015-01-19T05:00:00Z The Forbes story and a similar one in Salon cited a new review paper in an obscure Saudi Arabian journal about microscopy. Why Scientists Say Wi-Fi Signals Won't Give Your Kids Cancer 2015-01-19T05:00:00Z Once dominated by a method called X-ray crystallography, the field is now in the thrall of a technique called cryo-electron microscopy, or cryo-EM. 365 days: Nature's 10 In microscopy, if it takes a lot of effort to get to a microscopic image, then you only look where you’re expecting something specifically of high value. Digital Imaging On The Cutting Edge Of Tissue Analysis 2015-01-28T05:00:00Z Three hundred and fifty years later microscopy continues to expose the extraordinary in the mundane, deepening our understanding of the world we live in—sometimes to great aesthetic effect. Stunning Images from the 2014 Olympus BioScapes International Digital Imaging Competition 2014-12-16T05:00:00Z Expansion microscopy may permit scientists to create three-dimensional models of large areas in the brains of animals, making it possible to map biological processes from one region to the next. Expansion Microscopy Stretches Limits of Conventional Microscopes 2015-01-19T05:00:00Z The resulting images show individual nerves, touch receptors, and hair follicles stained in brilliant fluorescent colors that look more like abstract art than cutting-edge microscopy. The most detailed nerve images ever recorded are also the most psychedelic 2014-12-10T05:00:00Z The scientific community should set up centres to host and coordinate the high-power computing services needed to support high-resolution microscopy. Microscopy: Hasten high resolution 2014-11-25T05:00:00Z In an interview with Nature, Armitage said that he was also equally open about his roughly 30 technical articles on microscopy and his 2008 self-published book Jesus is like my Scanning Electron Microscope. University sued after firing creationist fossil hunter 2014-11-04T05:00:00Z But the campus operates as a limited company that aims to provide industry with research and services such as microscopy and crystallography, at a profit. After the Berlin Wall: Central Europe up close 2014-11-04T05:00:00Z The competition’s subject matter is unrestricted as long as some type of light microscopy technique is used, including phase contrast, polarized light, interference contrast, dark field or some combination thereof. Small Wonders: 20 Winning Images Depict Life under the Microscope [Slide Show] 2014-10-30T04:00:00Z And it’s typically faster than spinning disk confocal microscopy, one of the leading fluorescence microscopy methods. Video: 'Gentle' microscope captures tiny life in action 2014-10-23T04:00:00Z Other types of microscopy would also be improved with higher resolution. Microscopy: Hasten high resolution 2014-11-25T05:00:00Z Sam Lord, a microscopy specialist at the University of California, San Francisco, got all of his picks wrong on his Everyday Scientist blog. Nobel forecasting brings fun to online discussions 2014-10-14T04:00:00Z Hell developed a technique called stimulated emission depletion microscopy in 2000. Updated: Barrier-breaking microscopy methods that revealed cell's inner life win Nobel 2014-10-09T04:00:00Z Electron microscopy is able to resolve much smaller details than optical microscopy can manage, but because it must take place in a vacuum it cannot be used to study living samples. Blue’s brothers 2014-10-09T04:00:00Z Betzig, who shared this year’s Nobel Prize in chemistry for developing a different technique that greatly increased microscope resolution, and his colleagues show off the capabilities of lattice light-sheet microscopy online today in Science. Video: 'Gentle' microscope captures tiny life in action 2014-10-23T04:00:00Z Measuring the current between the two, as in scanning tunnelling microscopy, or the minute forces, as in atomic force microscopy, traces the structure of the surface. Microscopy: Hasten high resolution 2014-11-25T05:00:00Z This advance allowed nanoscale structures – including individual molecules – to be visualised within cells while they are still alive, something that isn’t possible with techniques such as electron microscopy. How Scientists Made Nano-Microscopes That Won The Chemistry Nobel Prize 2014-10-09T04:00:00Z It also adds details to the descriptions of the microscopy techniques for which the Nobel was awarded. Updated: Barrier-breaking microscopy methods that revealed cell's inner life win Nobel 2014-10-09T04:00:00Z Scientists long believed that optical microscopy would never be able to resolve distances smaller than half the wavelength of light, 0.2 micrometres. Nanoscopy pioneers win Chemistry Nobel : Nature News Blog 2014-10-07T04:00:00Z Two American scientists and one from Germany have won the Nobel prize for chemistry for the development of super-resolved fluorescence microscopy. Nobel prize for chemistry awarded to trio for pioneering microscope work 2014-10-08T04:00:00Z After the formal announcement, Sven Lidin, chair of the Nobel chemistry committee, explained the importance of the new microscopy in chemistry. 2014 Nobel Prize in Chemistry 2014-10-08T04:00:00Z The techniques they developed enabled extremely high resolution images to be produced using optical microscopy. How Scientists Made Nano-Microscopes That Won The Chemistry Nobel Prize 2014-10-09T04:00:00Z “It’s opened up the horizons of microscopy to new techniques, especially in the biological sciences.” Updated: Barrier-breaking microscopy methods that revealed cell's inner life win Nobel 2014-10-09T04:00:00Z In 2009 Nature interviewed Hell for a feature on this revolution in microscopy. Nanoscopy pioneers win Chemistry Nobel : Nature News Blog 2014-10-07T04:00:00Z The three scientists were cited for “the development of super-resolved fluorescence microscopy,” which the Royal Swedish Academy of Sciences said had bypassed the maximum resolution of traditional optical microscopes. 2 Americans, 1 German win Chemistry Nobel 2014-10-08T04:00:00Z Hell developed a technique called stimulate emission depletion microscopy in 2000. Barrier-breaking microscopy methods that revealed cell's inner life win Nobel 2014-10-08T04:00:00Z Their work circumvented the problem of the ‘diffraction limit’ – the inability of light microscopy to distinguish between structures smaller than half the wavelength of visible light or about 200nm. How Scientists Made Nano-Microscopes That Won The Chemistry Nobel Prize 2014-10-09T04:00:00Z For years, scientists believed that the resolution of optical microscopy was limited to half a wavelength of light, or 0.2 micrometers. Nobel Prize in chemistry honors scientists who saw beyond the limits of light 2014-10-08T04:00:00Z The researchers were so surprised, they deployed a battery of techniques to confirm the finding, including x-ray and neutron diffraction, transmission electron microscopy and vibrational spectroscopy. Liquid Benzene Squeezed to Form Diamond Nanofibers 2014-09-26T04:00:00Z “The performance of the technique appears to be comparable, if not superior, to routine microscopy,” says Richard Maude, an epidemiologist from the University of Oxford, UK. Quick test for malaria shows promise 2014-08-30T04:00:00Z Ma and Tschauner used various methods to characterize the extracted mineral, including so-called synchrotron X-ray diffraction mapping and high-resolution scanning electron microscopy. Earth's Most Abundant, Yet Elusive, Mineral Named After Nobel Prize Winner 2014-06-17T04:00:00Z As the fluorescent proteins were few and far between in the sample, those that glowed were generally more than 200nm apart – the diffraction limit for optical microscopy. How Scientists Made Nano-Microscopes That Won The Chemistry Nobel Prize 2014-10-09T04:00:00Z They encourage young scientists to return home, motivate governments to invest in their own science, and fill gaps in core technologies such as advanced microscopy and proteomics, which require sophisticated instruments. Capacity building: Architects of South American science 2014-06-10T04:00:00Z The team in China and the US used advanced microscopy to witness new connections between brain cells - synapses - forming during sleep. Sleep's memory role discovered 2014-06-05T04:00:00Z The conventional microscopy technique can detect the parasite only at concentrations of 50 cells per microlitre or higher, which is also when clinical symptoms can begin to appear. Quick test for malaria shows promise 2014-08-30T04:00:00Z To answer that, Dr. Seung analyzed a small bit of connectome from a portion of the retina created by automated electron microscopy. All Circuits Are Busy 2014-05-26T04:00:00Z A quantitative understanding of molecular exchange pathways in these one-dimensional aggregates was obtained by a combination of super-resolution stochastic optical reconstruction microscopy and stochastic simulation. [Report] Probing Exchange Pathways in One-Dimensional Aggregates with Super-Resolution Microscopy 2014-05-01T18:26:22.548Z The tiny creature's heart, measuring only slightly wider than a human hair, throbs and pumps blood cells into the surrounding network of vessels in the video created via light sheet microscopy. Videos of Live Embryos, Cancer Cell Win "Small World" Awards 2014-04-24T20:40:00Z The researchers’ method, injecting tracers into brain regions and using light microscopy to track the connections, showed not only the direction of information flow, but also the intensity of the connections between regions. The Map Makers: Brain-Mapping Milestones 2014-04-21T21:41:46Z Digital holographic microscopy image of red blood cells. First Artificial Red Blood Cells Made 2014-04-14T15:19:00Z The data are representative of four repetitions. b, ADP-ribosylation of actin induces actin aggregation that can be detected by fluorescence microscopy. Mechanism of Tc toxin action revealed in molecular detail 2014-04-04T18:24:45.845Z Atomic force microscopy revealed changes to the overall film profile with time at various temperatures. [Report] A Direct Quantitative Measure of Surface Mobility in a Glassy Polymer 2014-02-27T19:26:30.844Z Owing to an editorial oversight, accession numbers for the negative-stain electron microscopy maps for this Article were not obtained. Corrigendum: The architecture of Tetrahymena telomerase holoenzyme 2014-02-12T18:22:27.740Z Below is a sampling from the CDC’s electron microscopy files. Public Domain Treasures: The CDC’s Electron Micrographs Are Free To Use 2014-02-11T14:42:23Z Powerful developments in microscopy made possible movies of brain activity in living animals. The Mapmakers: The Brain, in Exquisite Detail 2014-01-10T04:08:28Z The data are representative of four repetitions. b, ADP-ribosylation of actin induces actin aggregation that can be detected by fluorescence microscopy. Mechanism of Tc toxin action revealed in molecular detail 2014-04-04T18:24:45.845Z Pardridge also questioned the methods used by Roche, characterizing them as “non-quantitative measures of brain uptake” and lambasting the study’s use of fluorescent microscopy as “a poor measure to quantify brain uptake.” Fooling Brain Defenses To Deliver an Alzheimer's Drug 2014-01-12T14:45:00.450Z The interface and the relative orientation of the two layers were determined by a variety of scanning microscopy and surface diffraction techniques. [Report] Heteroepitaxial Growth of Two-Dimensional Hexagonal Boron Nitride Templated by Graphene Edges 2014-01-09T18:56:28.015Z First-photon imaging may be of considerable value to both microscopy and remote sensing. [Report] First-Photon Imaging 2014-01-02T19:26:19.986Z One early adopter of super-resolution microscopy in immunology is Daniel Davis, a biophysicist at the University of Manchester in the UK. Medical imaging: Removing the blindfold 2013-12-18T18:50:58.412Z The elution fractions containing protein with the highest molecular weight were further examined by negative-stain electron microscopy, and samples containing the holotoxin complex were finally used for plunge freezing and cryo-EM. Mechanism of Tc toxin action revealed in molecular detail 2014-04-04T18:24:45.845Z But with skilful use of atomic force microscopy, researchers in Beijing managed to capture the first pictures of hydrogen bonds, seen here as faint lines between four molecules of 8-hydroxyquinoline. 365 days: Images of the year 2013-12-18T18:50:26.658Z The team took samples for microscopy and DNA analysis and made detailed floral measurements of hundreds of plants from populations of butterfly-orchids spread across nine islands. Rare orchid rediscovered in Azores 2013-12-10T12:01:16Z We used spinning-disk confocal microscopy to image the reorganization of cortical microtubule arrays in real time and visualize functional proteins tagged with fluorescent proteins. [Research Article] A Mechanism for Reorientation of Cortical Microtubule Arrays Driven by Microtubule Severing 2013-12-05T18:56:45.879Z Time-lapse microscopy techniques are beginning to provide a direct view of circuit dynamics in individual living cells. [Special Issue Review] Functional Roles of Pulsing in Genetic Circuits 2013-12-05T18:56:39.586Z An imaging technique called two-photon microscopy enabled the scientists to watch the movement of cerebrospinal fluid through a live mouse brain in real time. Brains flush toxic waste in sleep, study finds 2013-11-30T16:01:25Z The x-ray and electron microscopy E2 structures differ markedly from predictions of an extended, three-domain, class II fusion protein fold and therefore provide valuable information for HCV drug and vaccine design. [Report] Hepatitis C Virus E2 Envelope Glycoprotein Core Structure 2013-12-04T22:56:38.581Z An imaging technique called two-photon microscopy enabled the scientists to watch the movement of cerebrospinal fluid through a live mouse brain in real-time. Brains flush toxic waste in sleep, including Alzheimer’s-linked protein, study of mice finds 2013-10-19T20:31:09Z NSF applicants from a microscopy group at the University of Illinois at Urbana–Champaign sought a new scanning electron microscope, and included a plan to involve schoolchildren in the project. Impact: Pack a punch 2013-10-16T17:20:43.113Z The standard method for testing for TB in the clinic, smear microscopy, is not very fast. Diagnosis: Waiting for results 2013-10-09T17:20:59.757Z Using a technique called atomic force microscopy, scientists measured how the orientation of single atoms plays a crucial role in determining the strength of frictional forces between two materials. Why Friction Is a Drag: New Findings 2013-09-24T21:45:10.800Z The host cell receptor binding site was identified by electron microscopy and mutagenesis. [Report] Hepatitis C Virus E2 Envelope Glycoprotein Core Structure 2013-12-04T22:56:38.581Z "SRS microscopy allows us to see the margins on an microscopic scale." Laser-surgery gets edge on cancer 2013-09-05T01:19:18Z “We're using scanning electron microscopy and insects as a 'Trojan horse' to get kids interested in the possibility of science as a career choice,” says Scott Robinson, a microscopist at the university. Impact: Pack a punch 2013-10-16T17:20:43.113Z “With smear microscopy, if you run out of electricity you can just come back and finish your test later,” she says. Diagnosis: Waiting for results 2013-10-09T17:20:59.757Z Why Friction Is a Drag: New Findings Researchers used atomic force microscopy to study friction atom by atom. Why Friction Is a Drag: New Findings 2013-09-24T21:45:10.800Z Finally, we applied SRS microscopy in vivo in mice during surgery to reveal tumor margins that were undetectable under standard operative conditions. [Research Articles] Rapid, Label-Free Detection of Brain Tumors with Stimulated Raman Scattering Microscopy 2013-09-04T18:25:06.220Z A type of laser microscopy was used to look inside the brains of living mice to hunt for the dendritic spines. Cocaine 'rapidly changes the brain' 2013-08-25T17:41:25Z High-resolution transmission electron microscopy enabled a detailed analysis of interfacial site structure, which showed that the rate of CO oxidation on ceria was indeed enhanced greatly at interface sites. [Report] Control of Metal Nanocrystal Size Reveals Metal-Support Interface Role for Ceria Catalysts 2013-08-15T17:57:19.630Z By comparison, “a microscopy slide is less than one dollar.” Diagnosis: Waiting for results 2013-10-09T17:20:59.757Z I recommend checking it out, at least for the pretty microscopy. Theileria gets naked and rides the spindle 2013-07-27T11:45:00.660Z Cantilevers are an important part of atomic force microscopy, which is useful for making atomic scale resolutions of surfaces for use in nanotechnology or atomic physics research. Microscopic 'Tuning Forks' Could Make the Difference Between Life and Death in the Hospital 2013-06-30T18:00:00Z In this respect I try to understand and correlate the activity and structure of catalysts using transmission electron microscopy. 30 under 30: Changing the World Through Many Small Particles 2013-06-12T15:15:10.750Z The discovery of green fluorescent protein a half century ago heralded a new and explosive era in microscopy, forever changing the landscape for biology imaging. [Business Office Feature] Science Webinar Series: Fluorescent Probes and Digital Imaging: Where We Are and Where We're Going 2013-06-06T17:56:20.830Z One of the latest high-risk projects uses light-field microscopy, which records images from a variety of perspectives simultaneously, to image the brain. Neuroscience: Method man 2013-05-29T17:20:27.477Z And they used atomic force microscopy to take a closer look at how bacteria interact with this dental material. Fluoride Loosens Bacterial Enamel Grip 2013-05-23T00:45:00.707Z Microscope technology has been developed to make microscopy accessible to school children and inspiring a new generation. Capturing Scots science in pictures 2013-05-14T15:34:01Z I later applied for five postdocs, and three involved electron microscopy. Turning point: Lucy Collinson 2013-05-01T17:21:31.043Z Pratibha's work in molecular microscopy is opening up new worlds in the medical and material sciences. Science Weekly podcast: driving the Curiosity Mars rover 2013-04-16T06:30:03Z The research involves the use of a synchrotron and transmission electron microscopy coupled with microarrays to detect the proteins that catalyse the reactions. Microbiology: There's gold in them there bugs 2013-03-13T18:21:17.547Z Scanning electron microscopy identified pollen grains from myrtle, mint and other known embalming , as well as poplar and bellflower, which were in bloom when the king died. Forensic Exam of King Richard the Lionheart Reveals Embalming Practices 2013-03-01T18:15:00.213Z The researchers used electron microscopy and chemical analyses to examine 97 obsidian tools excavated earlier from a site called Tell Mozan, dating from the early Akkadian empire to several centuries after its demise. Fall of Ancient Empire Linked to Crisis in Syria 2013-02-22T20:15:00.507Z Lucy Collinson knew little about the machinery of cells when she started working in electron microscopy. Turning point: Lucy Collinson 2013-05-01T17:21:31.043Z Although our approach to calculating diffraction intensities from the model differs from that of Roorda and Lewis, paracrystallinity in amorphous silicon is undeniably evident in the raw experimental fluctuation electron microscopy data. [Technical Response] Response to Comment on “The Local Structure of Amorphous Silicon” 2012-12-20T21:25:57.750Z However, their models disagree with high-resolution x-ray measurements and other evidence, whereas the agreement with fluctuation electron microscopy is at best qualitative. [Technical Comment] Comment on “The Local Structure of Amorphous Silicon” 2012-12-20T21:25:50.123Z Electron microscopy images of the cubes are shown in . Controlled-reflectance surfaces with film-coupled colloidal nanoantennas 2012-12-11T21:22:39.403Z Wave-particle duality also finds it way in the applications of electron microscopy and neutron diffraction. The Chameleon of Quantum Culture: Wave-Particle Duality 2012-12-06T15:15:12.783Z To evaluate these tiny aberrations, Backman and his colleagues have developed an instrument that combines traditional microscopy with spectroscopy. Diagnostics: Playing detective 2012-11-23T15:21:10.310Z This work uses both well-established and novel tools, from atomic force microscopy and three-dimensional cell culture to fluorescent beads that track how cells change their environment. Mechanics: The forces of cancer 2012-11-23T15:20:56.230Z Publishing in the December issue of Earth and Planetary Sciences Letters, the authors Bridges and Schwenzer present an investigation of the mineralogical structures in one of the nakhlite rocks using electron microscopy. The Hot Baths of Mars 2012-11-16T15:45:02.767Z We didn't have a lab on board, and it's not a great big ship with the stability to do microscopy on board. Pacific Ocean Hacker Speaks Out 2012-10-28T20:20:26.867Z In electron microscopy, waves associated with the electron are used to examine objects. The Chameleon of Quantum Culture: Wave-Particle Duality 2012-12-06T15:15:12.783Z Students characterize the diverse microbes that emerge from the interior of symptomless tissue using traditional microbiology, microscopy, and molecular sequence analysis. [Essay] IBI* Series Winner: Student-Directed Discovery of the Plant Microbiome and Its Products 2012-10-28T19:55:58.967Z The researchers used x-ray tomographic microscopy and computational algorithms to generate detailed 3-D models of the ancient fossils. Ancient Armored Fish Had First Bad Bite 2012-10-17T18:15:00.943Z The performance employs juggling, clowning, and a big dance number—representing the crystal lattices that he studies with atomic microscopy. Dance Your PhD: And The Winner Is... 2012-10-15T06:19:42Z The researchers, led by biologist Gregory Erickson of Florida State University in Tallahassee, also used light and electron microscopy to examine the depth and directions of the abrasions on the surfaces of the teeth. Cows of the Cretaceous 2012-10-04T19:05:00Z Neutron diffraction basically does the same thing as electron microscopy. The Chameleon of Quantum Culture: Wave-Particle Duality 2012-12-06T15:15:12.783Z Electron microscopy also revealed significantly thinner myelin sheaths. The story of a lonely brain 2012-10-01T23:15:06.163Z The team, which included French and Spanish collaborators, used a variant of a technique called atomic force microscopy, or AFM. Striking image shows atomic bonds 2012-09-13T21:36:28Z Weber, a marine geologist, was studying the chemical composition of coral when he found that Eugene White, a scuba diver who was working with electron microscopy at the time, was also interested in coral. First Golden Goose Awards Honor Ideas That Hatched Unexpectedly 2012-09-10T21:42:30Z The difference in selenium supply has a negligible effect on CIGSSe grain structures, crystal orientation and bulk composition, when measured by cross-section scanning electron microscopy or TEM, X-ray diffraction and secondary ion mass spectrometry. Materials interface engineering for solution-processed photovoltaics 2012-08-15T17:22:03.163Z The researchers use a combination of microscopy and spectroscopy to examine how that light is reflected. Snap Judgment: Ultrafast Camera Renews Promise of Blood Test for Early Cancer Detection 2012-08-13T08:15:00.387Z Right now the only way to ensure getting every single connection in painstaking detail is to use electron microscopy to view synapses, the connections between neurons. It's all about sex: the connectome of a C. elegans male 2012-08-06T15:45:03.037Z Take an even closer look—this one requires microscopy—and you'll see something else, something embedded in the genetic blueprints of these young men and women that's just as important to their success. Unnatural Selection: Muscles, Genes and Genetic Cheats 2012-07-31T12:15:00.210Z The Trailblazing site by the Royal Society has a great timeline and links to some of the most important papers from Philosophical Transactions, including Newton’s report on optics and van Leeuwenhoek’s early microscopy work. The (mostly true) origins of the scientific journal 2012-07-28T11:45:08.887Z A 7 Å resolution cryoelectron microscopy map of Fab fragments of HM14c10 in a complex with DENV1 shows targeting of a discontinuous epitope that spans the adjacent surface of envelope protein dimers. [Research Articles] The Structural Basis for Serotype-Specific Neutralization of Dengue Virus by a Human Antibody 2012-06-20T18:55:24.963Z Dr. Denk developed microscopy techniques that allowed researchers to make three-dimensional maps of the internal wiring in brain tissues. Seven Scientists Win Kavli Prizes 2012-05-31T12:16:18Z Not only did mammary tumours form but, in autopsy studies using fluorescence microscopy, green pinpoints were also evident in various other organs. Metastasis: The rude awakening 2012-05-30T17:51:07.740Z But current microscopy tools are a limiting factor. Microglia: The constant gardeners 2012-05-30T17:50:34.540Z Without high-resolution images and microscopy, as well as a comparison of the actual fossils, however, they can't comment on whether the fossils belong to the same species, Shih added. Giant Flea-Like Pests Put the Bite on Dinosaurs 2012-05-03T20:45:03.307Z Last year researchers at Kansas State University exposed water-rich bacteria to electron microscopy after wrapping them in graphene treated with a protein that binds to the bacterium’s cell wall. Nanorama: Graphene Bubbles Showcase Liquids with Atomic-Scale Resolution 2012-04-05T19:15:00.253Z Seung: Using new methods of light microscopy, neurophysiologists are now able to image the signals of hundreds or even thousands of individual neurons at the same time, in the brains of living . MIT neuroscientist discusses quest to reverse engineer the entire human brain 2012-03-20T15:15:00.227Z The microscopy of the lesions is essentially the same as in the horse. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z Switching to electron microscopy would reveal the subcellular compartments that the virus exploits. Structural biologists share their toys 2012-02-29T18:20:39.100Z It is a variant of the atomic force microscopy that allowed the first molecular image in 2009. Electric image of single molecule 2012-02-26T20:19:54Z One unresolved question, he says, is whether liquid microscopy would reduce or increase the electron beam’s radiation effects compared with an alternative approach in which researchers prepare biological samples for imaging by freezing them. Nanorama: Graphene Bubbles Showcase Liquids with Atomic-Scale Resolution 2012-04-05T19:15:00.253Z Unlike electron microscopy, this does not require a cell to be chemically fixed, stained or embedded in plastic in order to be photographed. Microscopy: X-ray specs 2012-02-23T17:07:45Z The WHO recommends sputum smear microscopy, a test developed more than one hundred years ago, as the standard diagnosis. Totally Drug-Resistant TB Emerges in India 2012-01-13T18:15:02.853Z Recently included in Princeton University’s annual Art of Science exhibition, the image shows the progress made in this type of microscopy. What Is It? 2012-01-07T19:15:00.277Z Each wire was prepared by lithographically writing lines onto a silicon sample with microscopy techniques and then depositing phosphorus along that line. Ohm Run: One-Atom-Tall Wires Could Extend Life of Moore's Law 2012-01-05T20:45:02.433Z We want more field workers in every department of Natural History, and especially in microscopy where unexplored fields are awaiting you. Through a Microscope Something of the Science Together with many Curious Observations Indoor and Out and Directions for a Home-made Microscope. 2011-12-29T03:00:20.733Z The size of AZ cytomatrices is below the diffraction limit of light microscopy. [Report] RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release 2011-12-15T18:56:52.293Z And although microscopy is often pivotal in diagnosing common diseases, such as malaria, tuberculosis and other bacterial or parasitic diseases, in poor areas, “microscopy services are often suboptimal,” the researchers noted. Cell Phone Cameras Capture Microscopic Images to Diagnose Malaria and other Diseases 2011-12-15T03:15:00.433Z Although the technology to examine them — electron microscopy — wasn't new, it wasn't very popular at the time because “it was just old-fashioned”, says Raposo. Cell biology: The new cell anatomy 2011-11-30T18:20:28.260Z Maria McNamara, a paleobiologist at Yale University, and her colleagues used electron microscopy to study the moth’s scales, and then mathematically analyzed the scale structure to determine what the colors originally were. Observatory: Fossilized Moth?s Color Is Revealed With Microscopes and Math 2011-11-21T22:55:55Z A devoted student in microscopy will become so happy over the marvellous creatures and their curious ways that he cannot keep his pleasure to himself. Through a Microscope Something of the Science Together with many Curious Observations Indoor and Out and Directions for a Home-made Microscope. 2011-12-29T03:00:20.733Z Harald Hess, a group leader doing high-resolution microscopy at Janelia, who also spent 11 years at Bell, says that there are few time-sinks to keep scientists away from the bench at either institution. A roll of the dice 2011-11-16T18:20:43.990Z Many researchers want to apply new technologies, including increasingly sensitive molecular analyses and ever smarter microscopy, to developing brains to create a dynamic picture of what goes wrong. Tissue-bank shortage: Brain child 2011-10-26T17:20:49.553Z Scanning electron microscopy shows the fine structure of a nanotube connecting cultured rat cells. Cell biology: The new cell anatomy 2011-11-30T18:20:28.260Z Olympus will cut at least 30 billion yen in annual expense by March 2015, revive its imaging business and strengthen microscopy and industrial operations, Woodford said in May. Olympus Dismisses First Non-Japanese President, Shares Tumble 2011-10-14T10:07:03Z These techniques require more control over fluorophores than most scientists are used to, says Michael Davidson, director of the optical microscopy division at the National High Magnetic Laboratory in Tallahassee, Florida. Microscopy: Bright light, better labels 2011-10-05T17:20:40.413Z Once feathers were found, the samples were mounted on slides and polished, before being analyzed using microscopy. Amber Inclusions Showcase Prehistoric Feathers 2011-09-15T17:45:00.233Z Unlike microscopy, the coffee machine-sized instrument doesn't require a laboratory or trained personnel, she says. A Common TB Test Is Inaccurate, WHO Warns Countries 2011-07-22T18:22:20Z Scanning electron microscopy was used by paleontologists to look at the teeth of an extinct rodent and by invertebrate specialists to view the claws and other appendages of goblin spiders. On View: Specialized Windows on the Natural World 2011-07-11T21:42:06Z Pennycook, a pioneer of such techniques, has been pushing the limits of spatial resolution in electron microscopy to solve problems in a variety of research areas, including materials sciences, nanotechnology and condensed-matter physics. Misconduct at the DOE: Investigation closed 2011-07-06T17:20:18.643Z With or without dedicated instruments, researchers are keen to try their hand at super-resolution microscopy. Microscopy: Bright light, better labels 2011-10-05T17:20:40.413Z The microscopy also revealed how dark or light the feathers were. Amber Inclusions Showcase Prehistoric Feathers 2011-09-15T17:45:00.233Z Instead, WHO recommends that countries use standard microscopy or a new molecular testing system called GeneXpert. A Common TB Test Is Inaccurate, WHO Warns Countries 2011-07-22T18:22:20Z Using high-resolution confocal microscopy, Rodriguez-Diaz et al. demonstrated that human islets unexpectedly lacked the typical cholinergic neuronal innervation of mouse islets. [Editors' Choice] The Nerve of Those {beta} Cells 2011-07-05T19:27:24.540Z In the ace of Malaria, it is now possible to use a simple and rapid diagnostic test instead of microscopy. Lindau Nobel Meeting--The future of global health 2011-07-03T16:15:00.473Z For example, researchers at the University of Oxford, UK, adapted an algorithm originally developed to study crowded star systems, and used it in probe-based super-resolution microscopy. Microscopy: Bright light, better labels 2011-10-05T17:20:40.413Z In general, standard operating procedure in microscopy is a private, one-on-one, single user experience. The Socialization of Microscopes 2011-06-26T14:54:01Z Rachel Foster, profiled in one of my posts, was doing microscopy on the ship. Scientist at Work: Q. and A. on the Nitrogen Cycle 2011-05-26T15:57:10Z To test this hypothesis, the researchers combined a solution containing CdTe nanoparticles with one containing amyloid peptides and then examined the results using atomic force microscopy, transmission electron microscopy and other techniques. Nanoparticles Enlisted to Impede Alzheimer's-Inducing Brain Plaque 2011-05-20T10:15:05.220Z The researchers analysed the sizes and structures of ash particles using a variety of techniques, such as atomic force microscopy, scanning electron microscopy and X-ray diffraction. Aircraft ash fear 'well founded' 2011-04-25T20:10:55Z Licensing agreements restrict which acronyms each manufacturer uses in marketing, but a machine that works for one form of probe-based microscopy generally works for other forms as well. Microscopy: Bright light, better labels 2011-10-05T17:20:40.413Z I see this invention as the first shift in how the next evolution of microscopy will be implemented.” The Socialization of Microscopes 2011-06-26T14:54:01Z They make excellent laboratory stands for elementary courses in microscopy. Microscopes and Accessory Apparatus Catalogue No. 40 2011-04-14T02:00:42.743Z Part of the product-development process, says Freedman, was switching from opaque silicon chips to transparent plastic ones, to enable microscopy studies. Tissue models: A Living system on a chip 2011-03-30T17:21:20.057Z The new technology combines traditional optical microscopy with tiny particles, called transparent microspheres, that magnify images. Observatory: A Tool Gives a New View, Virus-Level, of the World 2011-03-07T21:24:25Z Setting up a probe-based super-resolution experiment is easy, but calculating localization spots does not guarantee resolution higher than that of conventional microscopy. Microscopy: Bright light, better labels 2011-10-05T17:20:40.413Z Together, those elements create an intuitive interface that interprets the entire concept of digital or web microscopy. The Socialization of Microscopes 2011-06-26T14:54:01Z Hooke popularized microscopy in his 1665 masterpiece Micrographia, which included stunning engravings of fleas, mites and the compound eyes of flies. Early Microscopes Offered Sharp Vision 2011-03-04T23:15:02.843Z This allowed researchers to see with their own eyes a level of detail that is normally restricted to indirect methods such as atomic force microscopy or scanning electron microscopy. Most powerful microscope unveiled 2011-03-01T18:38:32Z “This is just an alternative, to provide an opportunity for scientists to study using optical microscopy,” he said. Observatory: A Tool Gives a New View, Virus-Level, of the World 2011-03-07T21:24:25Z But electron microscopy requires elaborate preparation of samples: usually, cells must be 'fixed' with preservatives and then embedded in resin or frozen. Microscopy: Bright light, better labels 2011-10-05T17:20:40.413Z But now, a few researchers in Finland are changing that game based on their creation of an extreme microscope for web microscopy. The Socialization of Microscopes 2011-06-26T14:54:01Z The team imaged minuscule features in various solid samples and even the nanometre-scale grooves in Blu-Ray discs to show that the approach's resolution beat all previous records for optical microscopy. Most powerful microscope unveiled 2011-03-01T18:38:32Z Using the current technology, it is very time consuming; for example, using fluorescence optical microscopy, it takes two days to prepare one sample and the success rate of that preparation is 10 to 20%. Most powerful microscope unveiled 2011-03-01T18:38:32Z The researchers calculated how close different pieces of chromatin were to each other by dividing the genome into sections of just 20,000 base pairs, and confirmed several results with microscopy. Genomics: Genomes in three dimensions 2011-02-09T18:22:32.850Z Michael Davidson, director of optical microscopy at the National High Magnetic Laboratory in Tallahassee, Florida, recommends at least 100 milliwatts for green wavelengths, and up to 200 milliwatts for far-red. Microscopy: Bright light, better labels 2011-10-05T17:20:40.413Z Every year scientists and hobbyists alike submit their microscopy art to the Olympus BioScapes International Digital Imaging Competition. Life Unseen: Images of Magnificent Microscopic Landscapes [Slide Show] 2011-01-04T16:19:44.980Z Today, the most commonly used detection method in developing countries is smear microscopy. Detecting Tuberculosis: No Microscopes, Just Rats 2011-01-04T00:17:09Z Poling and his group are using the DNA test to verify results from the standard microscopy and the rat tests. Giant Rats Detect Tuberculosis 2010-12-23T17:07:00Z Until the beginning of this century, nearly all techniques that were used to study chromosome arrangements relied on microscopy. Genomics: Genomes in three dimensions 2011-02-09T18:22:32.850Z Many countries still rely largely on sputum smear microscopy for testing for TB, a diagnostic method developed more than 100 years ago. WHO says Cepheid rapid test will transform TB care 2010-12-08T10:37:00Z However, the resolution of conventional microscopy is limited. Cheek Swab May Detect Lung Cancer 2010-10-07T15:36:00Z It was only about 73 percent accurate on the hardest-to-analyze samples, but that is better than microscopy, which is wrong about half the time. Global Update: Tuberculosis: Automated Test for Drug-Resistant TB Gives Results in Hours, Not Weeks 2010-09-06T19:19:00Z Doctors say current diagnostic testing for TB -- which involves microscopy in labs with trained experts and can take weeks -- has barely been improved in the last 125 years. New test can diagnose tuberculosis in under 2 hours 2010-09-01T21:02:00Z But a strand of chromatin is only about 10 nanometres thick, and conventional fluorescence microscopy has a resolution at best of 200 nanometres. Genomics: Genomes in three dimensions 2011-02-09T18:22:32.850Z Scanning electron microscopy indicated that sharp-edged stones had created incisions on the bones. Lucy?s Kind Used Stone Tools to Butcher Animals 2010-08-13T14:32:00Z But the biggest knock on hair microscopy is that there are just no good data: there's no national database of hair evidence and no accepted statistics on how common any characteristics are. Postmortem: Seeking the Truth About an Executed Man 2010-05-20T17:25:00Z Oak Ridge is also developing a way to examine the molecular structure of liquids with a common technique called electron microscopy. Boosting Batteries For Electric Cars 2010-04-29T10:00:00Z |
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