| 单词 | melanocyte |
| 例句 | A topical gel or cream called immuno-modulators may restore some pigment by changing the immune system in the area where applied so that it doesn’t attack pigment-making cells, or melanocytes. Skin Deep: Vitiligo: Ignoring What Is Painfully Obvious 2010-02-24T20:28:00Z Older people develop gray or white hair because the melanocytes stop making pigment. Ever wondered about hair? 2015-02-27T05:00:00Z The science on green light isn’t as solid, but in theory, it targets melanocytes, discouraging excess melanin production. Can One LED Light Give You Perfect Skin? 2019-10-23T04:00:00Z Skin has pigmentation known as melanin that is provided by melanocytes. Fundamentals of Biology 2015-01-01T00:00:00Z The melanocyte stem cells in our hair follicles are responsible for producing and maintaining the pigment in our hair. Your Hair Is Going Gray. This Glitch May Explain Why. 2023-04-19T04:00:00Z The arrested development impacts immature cells which would otherwise have developed into melanocytes which give hair its natural colour or shade. Cause of grey hair may be 'stuck' cells, say scientists 2023-04-19T04:00:00Z The stratum basale also contains melanocytes, cells that produce melanin, the pigment primarily responsible for giving skin its color. Anatomy and Physiology 2013-06-19T00:00:00Z It’s a form of skin cancer that develops pigment-producing cells known as melanocytes. Kraken fan Nadia Popovici lauded for pointing out Canucks equipment manager Brian Hamilton’s cancerous mole during game 2022-01-01T05:00:00Z The average square inch of skin holds 650 sweat glands, 20 blood vessels, 60,000 melanocytes, and more than a thousand nerve endings. Fundamentals of Biology 2015-01-01T00:00:00Z Scientists assumed that gray hair was the result of that pool of melanocyte stem cells running dry. Your Hair Is Going Gray. This Glitch May Explain Why. 2023-04-19T04:00:00Z New hair grows from hair follicles, found in the skin, where the pigment-producing melanocytes also reside. Cause of grey hair may be 'stuck' cells, say scientists 2023-04-19T04:00:00Z Melanoma is the most dangerous form of skin cancer, affecting melanocytes, which can spread/metastasize to other organs. Anatomy and Physiology 2013-06-19T00:00:00Z Scientists still don’t know why some people turn gray early, late, or not at all, although they suspect genes, nutrients and possibly the immune system play a role in depleting melanocyte stem cells. Getting to the root of why and when our hair goes gray 2020-12-18T05:00:00Z This portion of the nail does not have any melanocytes, or melanin producing cells. Fundamentals of Biology 2015-01-01T00:00:00Z This “forced aging” led to a buildup of melanocyte stem cells stuck in their storage place, no longer producing melanin. Your Hair Is Going Gray. This Glitch May Explain Why. 2023-04-19T04:00:00Z As hair ages, sheds and then repeatedly grows back, increasing numbers of the melanocyte stem cells become sluggish at their job. Cause of grey hair may be 'stuck' cells, say scientists 2023-04-19T04:00:00Z Nevertheless, this hormone is capable of darkening of the skin by inducing melanin production in the skin’s melanocytes. Anatomy and Physiology 2013-06-19T00:00:00Z “How stress affects our tissues is still poorly understood, and one of the powerful aspects about the melanocyte is that it provides a visible and highly trackable system to study stress,” she says. Getting to the root of why and when our hair goes gray 2020-12-18T05:00:00Z The nail bed contains the blood vessels, nerves, and melanocytes, or melanin-producing cells. Fundamentals of Biology 2015-01-01T00:00:00Z Each hair follicle keeps immature melanocyte stem cells in storage. Your Hair Is Going Gray. This Glitch May Explain Why. 2023-04-19T04:00:00Z The stem cells stop roaming around the follicle and become fixed, thereby failing to mature into fully-fledged melanocytes. Cause of grey hair may be 'stuck' cells, say scientists 2023-04-19T04:00:00Z Many tissues that are not part of the nervous system also arise from the neural crest, such as craniofacial cartilage and bone, and melanocytes. Anatomy and Physiology 2013-06-19T00:00:00Z “Team Hair-Us” recently published a paper describing a topical drug combination that increased melanocyte stem cells in gray mice, ridding them of their gray and restoring their original fur color — perhaps for good. Getting to the root of why and when our hair goes gray 2020-12-18T05:00:00Z Tang et al. sequenced key parts of the genomes of cellular colonies derived from 133 individual melanocytes, collected from 19 body sites in 6 deceased donors. Seeds of cancer in normal skin 2020-10-06T04:00:00Z But as time wore on, the melanocyte cells couldn’t keep up the double act. Your Hair Is Going Gray. This Glitch May Explain Why. 2023-04-19T04:00:00Z "The newfound mechanisms raise the possibility that the same fixed-positioning of melanocyte stem cells may exist in humans. If so, it presents a potential pathway for reversing or preventing the greying." Cause of grey hair may be 'stuck' cells, say scientists 2023-04-19T04:00:00Z The second is a melanocyte, a cell that produces the pigment melanin. Anatomy and Physiology 2013-06-19T00:00:00Z “MITF, in a sense, shields melanocyte stem cells from our own immune system,” she says. Getting to the root of why and when our hair goes gray 2020-12-18T05:00:00Z Future studies to investigate melanocytes with surprisingly low numbers of mutations will be of interest to understand the origin and function of such cells. Seeds of cancer in normal skin 2020-10-06T04:00:00Z The strategy emerged from Le Poole’s research into how the immune system turns against pigmented skin cells called melanocytes. Temprian Therapeutics: developing a gene-based treatment for vitiligo 2020-06-29T04:00:00Z Most hairs were pigmented by melanocytes, which also develop from the cranial neural crest. Regenerative medicine could pave the way to treating baldness 2020-06-02T04:00:00Z Figure 5.8 Skin Pigmentation The relative coloration of the skin depends of the amount of melanin produced by melanocytes in the stratum basale and taken up by keratinocytes. Anatomy and Physiology 2013-06-19T00:00:00Z These stem cells, found near the base of each hair follicle, differentiate to form more specialized cells called melanocytes, which generate the brown, black, red and yellow hues in hair and skin. Stress Really Does Make Hair Go Gray Faster 2020-01-22T05:00:00Z The cancer-driving mutations found by the authors in scattered melanocytes might therefore represent the origins of some de novo melanomas. Seeds of cancer in normal skin 2020-10-06T04:00:00Z Le Poole suspects that dendritic cells draining into lymph nodes near application sites instruct T cells throughout the body to avoid melanocytes wherever they’re located. Temprian Therapeutics: developing a gene-based treatment for vitiligo 2020-06-29T04:00:00Z This results in mass migration of melanocytes away from the bulge, and leaves no remaining stem cells. How the stress of fight or flight turns hair white 2020-01-21T05:00:00Z The defect is primarily due to the inability of melanocytes to produce melanin. Anatomy and Physiology 2013-06-19T00:00:00Z At first, the team hypothesized that stress might cause an immune attack on melanocyte stem cells. Stress Really Does Make Hair Go Gray Faster 2020-01-22T05:00:00Z This carefully conducted study offers an unprecedented view of the landscape of somatic mutations in normal melanocytes, providing new clues about the origins of melanoma and presenting many intriguing observations that should motivate further research. Seeds of cancer in normal skin 2020-10-06T04:00:00Z The change in pigmentation of the skin is the result of melanocytes being attacked by the immune system’s T cells. Temprian Therapeutics: developing a gene-based treatment for vitiligo 2020-06-29T04:00:00Z Hair gets its colour from pigment-making cells called melanocytes that are found at the base of each hair. Grey hair may have roots in immune system 2018-05-02T04:00:00Z Other cells in the skin, such as melanocytes and dendritic cells, also become less active, leading to a paler skin tone and lowered immunity. Anatomy and Physiology 2013-06-19T00:00:00Z The researchers found that the sympathetic nerve cells released a neurotransmitter called noradrenaline that was taken up by nearby melanocyte stem cells. Stress Really Does Make Hair Go Gray Faster 2020-01-22T05:00:00Z Melanoma is a cancer that originates in melanocytes, the cells that produce the skin-color pigment melanin. How Cancer Can Become Therapy-Resistant 2018-04-07T04:00:00Z And as the pigs’ T cells attack tumours, they also kill melanocytes, causing vitiligo lesions. Temprian Therapeutics: developing a gene-based treatment for vitiligo 2020-06-29T04:00:00Z Melissa Harris at the University of Alabama at Birmingham and her colleagues engineered mice whose melanocyte precursors expressed lower levels of MITF. Grey hair may have roots in immune system 2018-05-02T04:00:00Z Recall that melanin is produced by cells called melanocytes, which are found scattered throughout the stratum basale of the epidermis. Anatomy and Physiology 2013-06-19T00:00:00Z In Dr. Hsu’s study, acute stress depleted the entire melanocyte stem cell population in mice in just five days. Stress Really Does Make Hair Go Gray Faster 2020-01-22T05:00:00Z “It is a failure of the stem cells in your hair follicles, called melanocyte stem cells, that happens with age.” Why Animals Get Gray Hair, Too 2017-07-08T04:00:00Z The approach can also be used for a selective “homeostatic reset” that diverts T cells from attacking melanocytes in the first place, Harris says. Temprian Therapeutics: developing a gene-based treatment for vitiligo 2020-06-29T04:00:00Z One of their compounds made a brown splotch, indicating that it was able to reach the melanocytes in the skin and spur melanin production, the team reports today in Cell Reports. Could this new compound give you a suntan—without the sun? 2017-06-13T04:00:00Z When there is an irregular accumulation of melanocytes in the skin, freckles appear. Anatomy and Physiology 2013-06-19T00:00:00Z The researchers also found that, in petri dishes, noradrenaline prompted human melanocyte stem cells to proliferate, suggesting that the same acceleration of hair graying occurs in people, too. Stress Really Does Make Hair Go Gray Faster 2020-01-22T05:00:00Z A. Hair goes gray as cells called melanocytes at the base of each hair follicle get damaged by disease, environmental exposures or age. Why Does Hair Turn Gray at a Young Age? 2017-06-09T04:00:00Z FB, forebrain; FP, floor plate; H, heart; HB, hindbrain; L, lens; M, melanocytes; MB, midbrain; O, otic vesicle; SC, spinal cord. The seahorse genome and the evolution of its specialized morphology : Nature : Nature Research 2016-12-13T05:00:00Z A patch of skin either contains melanocytes, or it doesn’t. Deciphering the genes that give mammals their stripes and patterns 2016-11-01T04:00:00Z Figure 5.9 Moles Moles range from benign accumulations of melanocytes to melanomas. Anatomy and Physiology 2013-06-19T00:00:00Z Research shows a gene change causes skin cells called melanocytes to stop making dark pigment in a particular area of the mouse's back, causing a white stripe. DNA clues to how chipmunk earned its stripes - BBC News 2016-11-02T04:00:00Z They discovered that pigment-producing cells called melanocytes did not develop as fully where light stripes appeared, so that less dark pigment was made there. Key to zebra stripes may be found in African mouse 2016-11-02T04:00:00Z FB, forebrain; FP, floor plate; H, heart; HB, hindbrain; L, lens; M, melanocytes; MB, midbrain; O, otic vesicle; SC, spinal cord. The seahorse genome and the evolution of its specialized morphology : Nature : Nature Research 2016-12-13T05:00:00Z If left unhindered, this gene would allow melanocytes to differentiate and produce dark pigment. Deciphering the genes that give mammals their stripes and patterns 2016-11-01T04:00:00Z In vitiligo, the melanocytes in certain areas lose their ability to produce melanin, possibly due to an autoimmune reaction. Anatomy and Physiology 2013-06-19T00:00:00Z Melanoma is generally caused when ultraviolet rays -- from the sun, or from artificial sources, such as tanning beds -- damage the DNA of melanocytes, according to the cancer society. Skin Cancer Check? Do Some Sole-Searching 2016-06-15T04:00:00Z Hair gets its colour from pigments produced by cells called melanocytes that sit in the hair follicle - the root of the hair. Grey hair gene discovered by scientists - BBC News 2016-03-01T05:00:00Z Oh no, I thought glumly, not you too, as if the greatness of being Oliver Sacks were enough to outsmart rapidly dividing melanocytes. Oliver Sacks, who has taught us so much, now teaches us the art of dying | Ranjana Srivastava 2015-07-25T04:00:00Z The treatment is a form of immunotherapy, in which a strand of DNA that's encoded for a protein normally found only on melanocytes is injected into a dog. How high-tech treatments add hope, and cost, to keeping a sick pet alive 2015-06-20T04:00:00Z Chromatophores contain pigment and control color expression in the skin — melanocytes in humans function the same way — but in cephalopods they also feature rings of muscle that allow them to expand, changing their color. Octopuses and other cephalopods can 'see' with their skin 2015-05-22T04:00:00Z The researchers exposed mouse and human melanocytes to radiation from a UV lamp. Sunbathers take heed: skin damage continues hours after exposure 2015-02-19T05:00:00Z As we age, the melanocytes stop producing the pigments and the hair loses its natural colour and goes grey. Grey hair gene discovered by scientists - BBC News 2016-03-01T05:00:00Z In melanocytes with melanin, DNA damage occurred not only immediately, but also hours after UV exposure ended. Sun's Damage Lingers Long After Dark 2015-02-19T05:00:00Z Melanoma is a deadly form of skin cancer that starts in the melanocytes, the cells that produce skin pigment. Airplane Crew May Face Increased Melanoma Risk 2014-09-10T04:00:00Z Melanoma begins in the melanocytes, which are the cells that produce melanin. Melanoma: Prevention, Warning Signs and Treatment 2013-08-10T12:00:00Z Many different cell types and tissues originate here, including cells of the peripheral nervous system, the adrenal medulla, melanocytes, and some skeletal cells. [Review] Tissue Interactions in Neural Crest Cell Development and Disease 2013-08-22T18:25:53.407Z Like skin melanoma, uveal melanoma is caused by specialized, pigment cells called melanocytes, but biologically it is "completely distinct from skin melanoma," Carvajal said in a telephone interview. Drug is a first to help patients with melanoma of the eye 2013-06-01T11:33:47Z Researchers exposed mouse and human melanocytes to UV radiation. Sun's Damage Lingers Long After Dark 2015-02-19T05:00:00Z Vitiligo is an autoimmune disease characterized by destruction of melanocytes, leaving 0.5% of the population with progressive depigmentation. [Research Articles] Mutant HSP70 Reverses Autoimmune Depigmentation in Vitiligo 2013-02-27T19:25:08.233Z And fewer melanin-producing melanocyte stem cells leads to greying hair, one of the most obvious signs of senior status. Stem cells: Repeat to fade 2012-12-06T12:21:18.613Z These clones targeted skin melanocytes in all five patients and persisted long term and reacquired parental T attributes in four patients after transfer. [Research Articles] The Stoichiometric Production of IL-2 and IFN-{gamma} mRNA Defines Memory T Cells That Can Self-Renew After Adoptive Transfer in Humans 2012-08-29T19:25:13.800Z Coat colour, an important consideration for many owners, is easily dealt with by picking the right pattern of melanocyte cells in the skin. Bespoke pets: Just press ?print? 2012-03-29T15:03:28Z Damage to melanocytes is a major cause of skin cancer, according to the researchers. Sun's Damage Lingers Long After Dark 2015-02-19T05:00:00Z Furthermore, use of therapeutically in a different, rapidly depigmenting model after loss of differentiated melanocytes resulted in 76% recovery of pigmentation. [Research Articles] Mutant HSP70 Reverses Autoimmune Depigmentation in Vitiligo 2013-02-27T19:25:08.233Z The white patches appear when pigment cells, called melanocytes, are attacked and destroyed by the body's immune system. Skin transplant surgery gives patients new lease on life 2011-11-07T16:42:14Z Using genetic mouse models, researchers were able to examine how Wnt signaling pathways enabled both hair follicle stem cells and melanocyte stem cells to work together to generate hair growth and produce hair color. New Research Provides Clues on Why Hair Turns Gray 2011-06-16T14:27:00Z This insight provides further understanding of diseases in which melanocytes are either appropriately lost such as hair graying or undergo uncontrolled cell growth as in melanoma. New Research Provides Clues on Why Hair Turns Gray 2011-06-16T14:27:00Z The study raises the possibility that Wnt signaling is a key pathway for the regulation of melanocyte stem cells and shows how melanocyte behavior is associated with hair regeneration. New Research Provides Clues on Why Hair Turns Gray 2011-06-16T14:27:00Z In a mouse model of depigmentation, DNA vaccination with a melanocyte antigen and the carboxyl terminus of HSP70i was sufficient to drive autoimmunity. [Research Articles] Mutant HSP70 Reverses Autoimmune Depigmentation in Vitiligo 2013-02-27T19:25:08.233Z We believe there is a short circuit due to genetics or due to an environmental cause or infection that causes the immune system to start thinking the melanocytes are a foreign object like an infection. Skin transplant surgery gives patients new lease on life 2011-11-07T16:42:14Z |
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