单词 | LDL cholesterol |
例句 | There is nothing unusual about coconut oil in this respect – all saturated fats raise both good HDL and bad LDL cholesterol levels. Coconut oil: are the health benefits a big fat lie? 2017-07-09T04:00:00Z It’s very dispiriting when people call each other vile names because they disagree about meat’s impact on LDL cholesterol. Perspective | Why making your diet part of your identity is bad for your health — and society 2020-09-23T04:00:00Z Most people know that in the realm of cooking fats, olive oil is considered a "good fat" because it is high in monounsaturated fatty acids, which can aid in lowering ones LDL cholesterol. New research shows olive oil could help reduce dementia-related deaths 2023-07-28T04:00:00Z An additional way to significantly reduce your total cholesterol and LDL cholesterol levels through diet is by eating more soluble fiber. How can I lower my cholesterol? Do supplements work? How about psyllium or probiotics? 2023-10-03T04:00:00Z This LDL cholesterol can build up in the walls of arteries and form plaques, leading to arteries hardening over time and increasing the risk of heart attack and stroke. Coronation Quiche is outrageously expensive to make. Here are cheaper and healthier options 2023-04-20T04:00:00Z If you’ve been diagnosed with high triglycerides, high LDL cholesterol, or low HDL cholesterol, those are signs that you may be insulin resistant and may want to consider lifestyle changes. Perspective | Explaining insulin resistance, and how to reverse it 2021-10-25T04:00:00Z High levels of LDL cholesterol in the blood can lead to the build-up of plaque in arteries, which leads to an increased risk of heart disease and stroke. How can I lower my cholesterol? Do supplements work? How about psyllium or probiotics? 2023-10-03T04:00:00Z "According to a study published in the journal Circulation in January 2020, coconut oil may enhance your LDL cholesterol levels, which is bad news for your heart." These are the worst cooking oils for your health, experts say 2022-03-19T04:00:00Z Too much of it causes the liver to overproduce “bad” LDL cholesterol, which is implicated in heart disease. Butter nonsense: the rise of the cholesterol deniers 2018-10-30T04:00:00Z In powder form, it’s used in beauty products and to lower LDL cholesterol for those with coronary heart disease. Perspective | Hints From Heloise: Do these oats take a powder? 2018-12-26T05:00:00Z The same analysis found it also raised harmful LDL cholesterol. Coconut oil: are the health benefits a big fat lie? 2017-07-09T04:00:00Z The concern over dairy stems from the recognition that saturated fat raises LDL cholesterol levels which are linked to heart disease. Dairy in moderation is good for heart health, study finds 2018-09-11T04:00:00Z In June, the American Heart Association suggested that the coconut oil beloved as a panacea by clean eaters actually had “no known offsetting favourable effects”, and that consuming it could result in higher LDL cholesterol. Why we fell for clean eating 2017-08-11T04:00:00Z Ms. Thompson, in her late 40s, has an LDL cholesterol level of 160 milligrams per deciliter, not high enough to make a statin imperative. A New Genetic Test Takes Aim at Young Hearts 2023-05-30T04:00:00Z But the heart association’s report noted that these improvements tend to be short-lasting, and that very-low-carb diets often cause an increase in LDL cholesterol levels, which can heighten the risk of heart disease. Popular keto and paleo diets aren’t helping your heart, report says 2023-04-27T04:00:00Z This drug does lower both total cholesterol and LDL cholesterol. How good is Nexletol against heart attacks? 2023-03-22T04:00:00Z Elevated levels of LDL cholesterol in your blood can lead to a buildup in your arteries, which in turn can lead to blood clots, heart attacks, and strokes. Do you need to shun sugar to lower cholesterol? 2023-03-20T04:00:00Z They can infiltrate the lining of blood vessels and usher in LDL cholesterol particles, thus contributing to atherosclerosis. Straight from the heart: Mysterious lipids may predict cardiac problems better than cholesterol 2023-03-15T04:00:00Z Ms. Elkins’s primary care doctor ordered a blood test, which revealed that her LDL cholesterol level was 160. A New Genetic Test Takes Aim at Young Hearts 2023-05-30T04:00:00Z Statin pills like Lipitor and Crestor – or their cheap generic equivalents – are the mainstay for lowering LDL cholesterol and preventing heart disease or treating those who already have it. Can’t take statins? New pill cuts cholesterol, heart attacks 2023-03-04T05:00:00Z Millions of Americans who are at high risk for heart attacks and whose LDL cholesterol levels are disturbingly high have been told over and over again by their doctors to take a statin. A Statin Alternative Joins Drugs That Can Reduce Heart Attack Risk 2023-03-04T05:00:00Z HDL helps prevent a buildup of LDL cholesterol, which is why it’s often referred to as “good” cholesterol. Do you need to shun sugar to lower cholesterol? 2023-03-20T04:00:00Z The traditional factors for assessing this risk include age, sex, whether the patient smokes or has diabetes, and lab measurements of lipids such as LDL cholesterol. Straight from the heart: Mysterious lipids may predict cardiac problems better than cholesterol 2023-03-15T04:00:00Z Q: My LDL cholesterol is a bit high, but I’d rather not take a statin. Will bergamot lower cholesterol and triglycerides? 2023-01-25T05:00:00Z “We found that the saturated fat in cheese did not raise LDL cholesterol levels to the same degree as butter did,” she says. Good news about cheese — it’s much healthier than you thought 2023-01-02T05:00:00Z The two drugs, which lower "bad" LDL cholesterol by blocking a protein called PCSK9 that prevents its removal from the blood, can reduce the risk of heart attacks and strokes in people with heart disease. U.S. Supreme Court to hear Amgen bid to revive cholesterol drug patents 2022-11-04T04:00:00Z Research has found that consuming too much dietary sugar can lower levels of HDL cholesterol and increase levels of LDL cholesterol and triglycerides. Do you need to shun sugar to lower cholesterol? 2023-03-20T04:00:00Z In contrast, LDL cholesterol provided no insight—it was higher in the people who didn’t have heart attacks, the scientists reported. Straight from the heart: Mysterious lipids may predict cardiac problems better than cholesterol 2023-03-15T04:00:00Z Can you tell me how effective bergamot is for lowering LDL cholesterol and triglycerides? Will bergamot lower cholesterol and triglycerides? 2023-01-25T05:00:00Z Because healthful plant-based eating patterns contain a wealth of beneficial elements including fiber, heart-healthy fats, antioxidants, potassium and other nutrients, even being semi-vegetarian can decrease LDL cholesterol by 10%-15%. Eating plant-based for health isn’t an all-or-nothing deal 2022-10-17T04:00:00Z In addition to lowering triglycerides, it also can reduce total and LDL cholesterol and raise “good” HDL cholesterol. Extra benefits from fenofibrate 2022-09-28T04:00:00Z According to a 2016 research review, as sugar intake increases, LDL cholesterol levels go up, whereas HDL cholesterol levels go down. Do you need to shun sugar to lower cholesterol? 2023-03-20T04:00:00Z Her other lipids, including LDL cholesterol and total cholesterol, also improved. Straight from the heart: Mysterious lipids may predict cardiac problems better than cholesterol 2023-03-15T04:00:00Z Cardiologists have known for almost 60 years that this blood lipid is probably as dangerous as LDL cholesterol. What happened to the flu this year? 2022-02-23T05:00:00Z As a result, people with familial hypercholesterolemia have abnormally high levels of LDL cholesterol and, if left untreated, are up to 13 times more likely to develop coronary heart disease than someone without the mutation. Is There More to a Healthy-Heart Diet Than Cholesterol? 2021-12-02T05:00:00Z Current research has also found no differences in lowering total cholesterol, “bad” LDL cholesterol, triglycerides, blood pressure, blood sugar or A1c. What to know if you’re considering intermittent fasting 2021-11-29T05:00:00Z The authors of a 2020 review of randomized controlled trials suggested that replacing fructose or sucrose with starch — a complex carbohydrate made up of glucose — may lower LDL cholesterol levels. Do you need to shun sugar to lower cholesterol? 2023-03-20T04:00:00Z Long overlooked, they are emerging as powerful alternatives to standard markers of heart disease risk such as LDL cholesterol. Straight from the heart: Mysterious lipids may predict cardiac problems better than cholesterol 2023-03-15T04:00:00Z Gamma-tocopherol has been shown to inhibit oxidation of bad LDL cholesterol — important, because oxidized LDL contributes to inflammation in the arteries and is a risk factor for cardiovascular disease. Here are 5 delicious, nutritious foods to build your plate around this Thanksgiving 2021-11-22T05:00:00Z The advent of statins—medication that lowers LDL by inhibiting a cholesterol-producing enzyme in the liver—reinforced the view that LDL cholesterol has a substantial role in heart disease. Is There More to a Healthy-Heart Diet Than Cholesterol? 2021-12-02T05:00:00Z It turns off, or silences, a gene called PCSK9, which results in the liver absorbing more "bad" LDL cholesterol from the blood and breaking it down. Life-saving cholesterol jab recommended on NHS 2021-08-31T04:00:00Z We saw both statistically and clinically significant drops in LDL cholesterol, which is the bad cholesterol. The ‘Hedonistic Altruism’ of Plant-Based Meat 2021-08-27T04:00:00Z “The two together are synergistically bad for raising LDL cholesterol.” Eating too many eggs can still be risky, but most people don’t have to give them up entirely, experts say 2021-07-30T04:00:00Z Chylomicrons keep LDL cholesterol in circulation, giving it ample opportunity to get stuck in arteries. Does Coconut Oil Deserve Its Health Halo? 2021-01-04T05:00:00Z In gold-standard randomized controlled trials, people replace saturated fats in their diets with polyunsaturated fatty acids, such as those found in vegetable oil, and this reduces the levels of LDL cholesterol in the blood. Is There More to a Healthy-Heart Diet Than Cholesterol? 2021-12-02T05:00:00Z Watch your LDL cholesterol, a strong driver of heart disease, and eat a largely plant-based diet to help lower it if necessary. How ‘Fast Carbs’ May Undermine Your Health 2020-04-14T04:00:00Z In studies involving those patients, it reduced LDL cholesterol by 28 percent, the company said. FDA approves first non-statin pill to treat high cholesterol in almost two decades 2020-02-21T05:00:00Z This increased consumption was associated with a mean LDL cholesterol, what’s known as “bad” cholesterol, increase of 15 milligrams per deciliter of blood. Cholesterol studies promoted the sunny side of eggs, but the research was hatched out of industry funding 2019-12-13T05:00:00Z The soluble fiber in beans and oats, for example, may help to lower blood levels of artery-damaging LDL cholesterol. Fiber in Fruits and Grains Protects Against Diverticulitis 2019-10-28T04:00:00Z He points out that research co-authored by Ravnskov found that people with the highest level of LDL cholesterol seem to live longer than those with the lowest levels9. Is There More to a Healthy-Heart Diet Than Cholesterol? 2021-12-02T05:00:00Z A phase III trial of the drug in people who had experienced a heart attack or stroke showed a roughly 50% decrease in LDL cholesterol levels. Why rare genetic diseases are a logical focus for RNA therapies 2019-10-15T04:00:00Z Recommended cholesterol levels vary by age and gender, but the “optimal” level for LDL cholesterol is 100 milligrams per deciliter or below, according to the National Heart, Lung and Blood Institute. FDA approves first non-statin pill to treat high cholesterol in almost two decades 2020-02-21T05:00:00Z Both drugs dramatically lower “bad” LDL cholesterol by blocking a protein known as PCSK9 that prevents LDL removal from the blood. U.S. judge rules for Regeneron, Sanofi in Amgen cholesterol drug... 2019-08-28T04:00:00Z VLDL, or very low-density lipoproteins, is a precursor to LDL cholesterol, which is commonly seen as a major risk factor for cardiovascular disease. A new study links sugary drinks with disease. The reality is more complicated. 2019-05-01T04:00:00Z This protein usually removes LDL cholesterol from the blood, but in people with the condition it is faulty. Is There More to a Healthy-Heart Diet Than Cholesterol? 2021-12-02T05:00:00Z A 1.0 mmol/L reduction in LDL cholesterol lowered the risk of major vascular events by about a fifth and a major coronary event by a quarter, when results from all age groups were combined. More over-75s 'should take statins' 2019-01-31T05:00:00Z It is created from antibodies that dramatically lower levels of “bad” LDL cholesterol in the blood by blocking a certain protein. U.S. Supreme Court rejects Amgen over cholesterol medication patent... 2019-01-07T05:00:00Z Which raises the question, “What is a healthy level of both HDL and LDL cholesterol?” HDL Cholesterol: Too Much of a Good Thing? 2018-12-24T05:00:00Z Together, they discovered that patients with FH lack LDL receptors and exhibit increased LDL cholesterol production. The Widening Chasm between Research and Clinical Practice 2018-11-30T05:00:00Z In the early 1990s, the Scandinavian Simvastatin Survival Study showed that the statin simvastatin was effective at lowering LDL cholesterol and reducing the risk of a heart attack4. Is There More to a Healthy-Heart Diet Than Cholesterol? 2021-12-02T05:00:00Z Michels based her warning on the high proportion of saturated fat in coconut oil, which is known to raise levels of so-called LDL cholesterol, and so the risk of cardiovascular disease. Coconut oil is 'pure poison', says Harvard professor 2018-08-22T04:00:00Z They have borderline levels of LDL cholesterol, the dangerous kind. Clues to Your Health Are Hidden at 6.6 Million Spots in Your DNA 2018-08-13T04:00:00Z However, the level of LDL cholesterol tells a different story. HDL Cholesterol: Too Much of a Good Thing? 2018-12-24T05:00:00Z None found the benefits as promised, and one's LDL cholesterol and liver enzymes were threw the roof and another nearly died of pulmonary embolism. A Better Body in a Pill? Experts Urge Caution on SARMs 2018-04-12T04:00:00Z She adds that clinical guidelines for the treatment of high cholesterol tend to focus on the bad cholesterol, in part because that’s what the drugs target: Statins lower LDL cholesterol. Statins help lower cholesterol, but are they the treatment for you? 2018-02-23T05:00:00Z In middle age, they had higher levels of triglycerides and LDL cholesterol. The Famine Ended 70 Years Ago, but Dutch Genes Still Bear Scars 2018-01-31T05:00:00Z More than a decade later, in 2001, doctors for President Bill Clinton, concerned about an increase in his weight and elevated LDL cholesterol levels, started the president on statin drugs to treat those symptoms. Trump Is in ‘Excellent Health,’ Doctor Says After Exam 2018-01-12T05:00:00Z They aggressively lower patients’ LDL cholesterol, optimize their blood pressure and blood sugar, and strongly encourage healthy diet and exercise habits. A Heart Risk Factor Even Doctors Know Little About 2018-01-09T05:00:00Z LDL cholesterol is deeply entrenched in medical routines, and "it's not going to change any time soon," Rader says. Is it time to retire cholesterol tests? 2017-12-06T05:00:00Z These people are considered high risk because we know high LDL cholesterol is a strong risk factor for atherosclerotic cardiovascular disease. Am I at High Risk for a Heart Attack? 2017-11-24T05:00:00Z Is my blood level of that nasty LDL cholesterol in check—say, below 100 mg/dL? Strict Targets for Cholesterol, Blood Pressure, and More Don't Always Make Sense 2017-11-20T05:00:00Z Almonds are high in monounsaturated fats, which may explain why they’ve been shown to lower “bad” LDL cholesterol while maintaining — or even improving — “good” HDL cholesterol. You should be eating more nuts 2017-11-13T05:00:00Z Those who took olive oil saw their heart rate variability decline when inhaling the pollution; levels of unhealthy LDL cholesterol and triglycerides also went up — two risk factors for heart disease. Opinion | Does Eating Right Protect You From Air Pollution? 2017-10-19T04:00:00Z Although these people showed further decreases in LDL cholesterol, their apoB levels—and their cardiovascular risk—didn't decline by as much. Is it time to retire cholesterol tests? 2017-12-06T05:00:00Z A lifelong exposure to very high LDL cholesterol, caused by this genetic disorder that affects 1 in 250 people, can dramatically increase your risk for an early heart attack. Am I at High Risk for a Heart Attack? 2017-11-24T05:00:00Z “When we looked, there was one variant that was more certain, for LDL cholesterol, and the gene the Vindija individual carried is protective,” Prüfer says. New Clues to How Neanderthal Genes Affect Your Health 2017-10-05T04:00:00Z Research had shown that high levels of LDL cholesterol in blood were linked with an increased risk of heart disease and stroke, and we knew eggs were packed with cholesterol. Nutrition science isn’t broken, it’s just wicked hard 2017-07-21T04:00:00Z Take Inclisiran, a drug that recently completed Phase 2 trials in which it showed remarkable reductions in LDL cholesterol levels. High Drug Prices Are Bad. Cutting Them Could Be Worse. 2017-06-30T04:00:00Z Total cholesterol level was the first widely used indicator of this risk, but after researchers discovered that one form of cholesterol, HDL, may be protective, LDL cholesterol became the benchmark. Is it time to retire cholesterol tests? 2017-12-06T05:00:00Z FH is passed down in families, so if you have early heart disease in your family and very high LDL cholesterol from a young age, please get evaluated and get your kids cholesterol checked too. Am I at High Risk for a Heart Attack? 2017-11-24T05:00:00Z But lowering LDL cholesterol is only one factor in the complexity of factors that influence arterial health. Dr. Andrew Weil Says We’re Taking Too Many Medicines 2017-06-22T04:00:00Z We all need it, but too much "bad" LDL cholesterol increases the risk of cardiovascular diseases. Cholesterol-lowering jab to help prevent heart disease - BBC News 2017-06-19T04:00:00Z Michael Joyner, a medical doctor and integrative physiology researcher at the Mayo Clinic in Rochester, Minnesota, also notes that over 70% of the participants are currently taking prescribed medication for high LDL cholesterol and hypertension. This $25,000 physical has found some ‘serious’ health problems. Others say it has serious problems 2017-05-12T04:00:00Z At the same time, some people taking drugs for what seem to be dangerously high LDL cholesterol levels may not need treatment, Sniderman says. Is it time to retire cholesterol tests? 2017-12-06T05:00:00Z Their aim is primarily to reduce LDL cholesterol, not provide blanket assurance of "perfect cholesterol readings." Heart Attack Survivors Often Fail to Take Statins 2017-04-24T04:00:00Z These include reduced insulin sensitivity, higher blood-sugar levels and increases in LDL cholesterol and triglycerides. Coated aspirin may be riskier for digestive tract 2017-04-09T04:00:00Z In addition to tracking body mass index, physical activity, and demographic and behavioral characteristics, they assessed four risk factors for cardiovascular disease: LDL cholesterol, triglycerides, blood pressure and glucose tolerance. Healthy Weight? You May Still Be at Risk for Heart Disease 2017-04-06T04:00:00Z It may seem obvious that lowering LDL cholesterol would inevitably reduce the risk of heart disease. An End to Heart Disease? Not Quite 2017-03-20T04:00:00Z "The argument is that LDL cholesterol is good enough," he says. Is it time to retire cholesterol tests? 2017-12-06T05:00:00Z The data reinforce the growing body of evidence showing that as clinicians push LDL cholesterol levels ever lower, their patients fare better. Powerful heart drug sharply cuts risks for cardiac patients on statins 2017-03-17T04:00:00Z Red yeast rice supplements are touted as a way to reduce “bad” LDL cholesterol. Some good reasons to be cautious about using dietary supplements 2017-02-10T05:00:00Z Research suggests that green tea helps to reduce total cholesterol, and that both green and black teas help reduce “bad” LDL cholesterol and lower blood pressure. Is a cup of tea good for you? 2017-01-18T05:00:00Z In 2015, the Food and Drug Administration approved a new class of drugs for the reduction of LDL cholesterol, the type associated with heart disease and stroke. An End to Heart Disease? Not Quite 2017-03-20T04:00:00Z It said Praluent, a drug intended to lower "bad" LDL cholesterol by blocking a protein known as PCSK9, infringed its patents related to the protein. U.S. Judge Blocks Sanofi and Regeneron From Selling Cholesterol Drug 2017-01-05T05:00:00Z Currently, an LDL cholesterol below 100 is considered optimal for people at risk of heart disease, according to the Mayo clinic. Powerful heart drug sharply cuts risks for cardiac patients on statins 2017-03-17T04:00:00Z He also began taking a statin to lower his elevated LDL cholesterol level. He was set for surgery — until another doctor said the diagnosis was all wrong 2016-12-09T05:00:00Z But the different trials showed that each unit of LDL cholesterol removed from the bloodstream protects heart health, regardless of how doctors are able to drive those cholesterol levels down. Are There Alternatives to Statins? 2016-09-27T04:00:00Z “If you look at older versions of the guidelines, there was a focus on getting LDL cholesterol down through a series of different options,” says Sabatine. Statins Aren't the Only Way to Lower Cholesterol 2016-09-27T04:00:00Z They also prevent stroke and heart attack-triggering plaque from building up within the arteries, while also showing significant ability to lower "bad" LDL cholesterol levels. The Ultimate Grocery Shopping List to Replace Your Medicine Cabinet 2016-09-26T04:00:00Z He said the main criteria for him would be an analysis of the patient's baseline risk and those most likely to see the largest reduction in LDL cholesterol. Powerful heart drug sharply cuts risks for cardiac patients on statins 2017-03-17T04:00:00Z But the levels were in the normal range in the recent tests: cholesterol, 169; HDL cholesterol, 63; LDL cholesterol, 94; triglycerides, 61. A Doctor’s Assessment of Whether Donald Trump’s Health Is ‘Excellent’ 2016-09-18T04:00:00Z "There is a linear relationship between what your LDL cholesterol level is and what your risk is of cardiovascular events," Sabatine said. Are There Alternatives to Statins? 2016-09-27T04:00:00Z And he said he was wrong to encourage people to consume saturated fat because it increases LDL cholesterol, which correlates with heart disease. An Unconventional Cardiologist Promotes a High-Fat Diet 2016-08-23T04:00:00Z Trumps LDL cholesterol is considered in the optimal range, at 94 mg/dL. What Trump's Health Stats Mean 2016-09-15T04:00:00Z However, HDL and LDL cholesterol levels are important, he says, especially HDL – the good cholesterol. 10 Commandments to Reduce Your Risk of Stroke 2016-08-10T04:00:00Z Now, in a study published in the journal Circulation, researchers find that changes in levels of LDL cholesterol may be especially harmful to cognitive functions. Here's What Cholesterol Can Do To the Brain 2016-07-18T04:00:00Z She said the evidence review "supports that there are several options to lower LDL cholesterol and they all lower risk for cardiovascular disease." Are There Alternatives to Statins? 2016-09-27T04:00:00Z This sequence of events may even overshadow the effects of LDL cholesterol, the so-called bad kind. Is Sugar Really Bad for You? It Depends 2016-06-08T04:00:00Z Both drugs were introduced last year to reduce levels of LDL cholesterol, or “bad” cholesterol, beyond what can be achieved by an older class of drugs known as statins. Health Insurers Push to Tie Drug Prices to Outcomes 2016-05-11T04:00:00Z “These new therapies offer additional LDL cholesterol lowering and outcomes studies are still pending,” said the firm. Breakthrough cholesterol drugs fizzle amid price pushback 2016-04-20T04:00:00Z The scientists, led by Dr. Roelof Smit at Leiden University Medical Center in the Netherlands, studied 535 elderly people enrolled in a study involving a statin, a medication that lowers LDL cholesterol. Here's What Cholesterol Can Do To the Brain 2016-07-18T04:00:00Z LDL cholesterol is quickly followed by white blood cells and thus begins the process of plaque formation, consisting mainly of cholesterol, fatty substances and waste products of cells. Inflammation and Heart Disease: What Is C-Reactive Protein? Who Might Benefit from Testing? 2016-04-06T04:00:00Z “What many people don’t realize is that it’s triglycerides and HDL that are more predictive of cardiovascular disease than LDL cholesterol,” Dr. Malhotra said. Is Sugar Really Bad for You? It Depends 2016-06-08T04:00:00Z In another study released Sunday morning, researchers showed that a drug that raises HDL cholesterol, the so-called good cholesterol, and lowers LDL cholesterol does not help high-risk heart patients. Statin intolerance is real, researchers find. Another (more costly) drug may get around the problem. 2016-04-03T04:00:00Z It is a drug that reduces levels of LDL cholesterol, the dangerous kind, as much as statins do. Dashing Hopes, Study Shows a Cholesterol Drug Had No Effect on Heart Health 2016-04-03T04:00:00Z These foods also appear to help lower blood levels of "bad" LDL cholesterol, he added. Beans, Chickpeas May Help With Weight Loss: Study 2016-03-30T04:00:00Z The study showed a greater reduction in both LDL cholesterol and hsCRP with the combination of drugs. Inflammation and Heart Disease: What Is C-Reactive Protein? Who Might Benefit from Testing? 2016-04-06T04:00:00Z For instance, for LDL cholesterol, both Theranos and LabCorp reported results out of the normal range for many of the same people, while Quest reported normal levels for them. Study of Theranos Medical Tests Finds Irregular Results 2016-03-28T04:00:00Z The Food and Drug Administration approved PCSK9 inhibitors last year, but only for small groups of people, including those with an inherited disease that dramatically elevates their LDL cholesterol levels. Statin intolerance is real, researchers find. Another (more costly) drug may get around the problem. 2016-04-03T04:00:00Z Compared to the muffin eaters, the almond eaters reduced their LDL cholesterol, belly fat and waist circumference, suggesting that almonds trump high-carb snacks in preventing heart disease and diabetes. 10 Foods Every Plant-Based Diet Needs 2016-03-24T04:00:00Z LDL cholesterol is believed to collect in the walls of blood vessels, ultimately blocking the flow of blood and leading to heart attacks and strokes. 'Good' cholesterol mutation linked to heart disease 2016-03-09T05:00:00Z Yet there are still recommendations to limit saturated fat because it raises total cholesterol and LDL cholesterol. Making a Case for Eating Fat 1464-03-31T05:00:00Z A brochure for the Four Sigmatic elixir echoes the general wellbeing and heart health claims, saying “reishi reduces the possibility of heart disease” by lowering the LDL cholesterol levels and blood pressure. Mushroom Hot Cocoa Is Now a Thing 2016-03-02T05:00:00Z The monthly injections of the PCSK9 inhibitor proved far more effective after 24 weeks, cutting patients' LDL cholesterol by an average of 52.8 percent, compared to 16.7 percent for the other drug. Statin intolerance is real, researchers find. Another (more costly) drug may get around the problem. 2016-04-03T04:00:00Z Whole grains also help lower “bad” LDL cholesterol and blood pressure and promote stable blood-sugar levels to keep Type 2 diabetes at bay. Eat and Drink Your Way to a Healthier Heart 2016-02-17T05:00:00Z A large body of genetic and molecular studies, and the rampant success of some drugs that lower LDL cholesterol, back up this idea. 'Good' cholesterol mutation linked to heart disease 2016-03-09T05:00:00Z Statins interfere with the production of cholesterol by the liver, and thus help lower "bad" LDL cholesterol and raise "good" HDL cholesterol levels in the bloodstream, according to the U.S. U.S. Task Force Backs Statins for Those 40 to 75 at Heightened Heart Risk 2015-12-21T05:00:00Z Why it’s good for you: Endive is high in inulin and fiber, which can lower LDL cholesterol levels to benefit the heart. The 50 (New) Healthiest Foods of All Time—With Recipes 2015-11-23T05:00:00Z The scientists had been investigating a liver protein, dubbed PCSK9, that's responsible for circulating harmful LDL cholesterol in the human body. And the Oscar of Science Goes To … 2015-11-08T05:00:00Z Only patients in the shared physician-patient incentives group achieved reductions in LDL cholesterol levels that were statistically different from those in the control group, the researchers found. 'Cash for Lower Cholesterol' Program Works With Doc-Patient Teams 2015-11-08T05:00:00Z Research also shows that lentils help reduce total and LDL cholesterol, the risk of heart attack and chronic inflammation. 7 Pantry Essentials Dietitians Always Have On Hand 2015-11-05T05:00:00Z On average, the subjects’ LDL cholesterol, the kind implicated in heart disease, fell by 10 points. Cutting Sugar Improves Children's Health in Just 10 Days 2015-10-27T04:00:00Z Two drugs, known as PCSK9 inhibitors, were approved this year, promising to reduce the level of “bad” LDL cholesterol far more than cheaper drugs called statins. Medicare spending for hepatitis C cures surges 2015-10-16T04:00:00Z Her mother died of a heart attack and Mrs. Barnett knew her level of LDL cholesterol, the bad kind, was very high at 190. Heart Scan Can Fine-Tune Risk Estimate for Patients Considering Statins 2015-10-05T04:00:00Z Patients who received automated text messages throughout their week saw improvements in their "bad" LDL cholesterol levels, blood pressure and weight, the study found. Could a Texting App Help Your Heart? 2015-09-22T04:00:00Z Dr. Gattuso also broke from the current orthodoxy in his distaste for statins, medicines that reduce harmful LDL cholesterol in the blood. ‘Be Well Weekend’ at Omni Bedford Springs Resort teaches health, diet secrets 2015-09-13T04:00:00Z In clinical trials they lowered the level of LDL cholesterol, the so-called bad kind, by 40 percent or more, even when patients were already taken statins. New Cholesterol Drugs Are Vastly Overpriced, Analysis Says 2015-09-08T04:00:00Z The companies are conducting cardiovascular outcomes trials to determine whether their ability to dramatically lower bad LDL cholesterol will lead to fewer heart attacks, strokes and deaths. FDA Approves New Cholesterol-Lowering Drug 2015-08-28T04:00:00Z In a clinical study, participants taking Repatha saw an average drop in LDL cholesterol of about 60 percent, compared with those who took a placebo, the FDA said. FDA Approves Repatha for High Cholesterol 2015-08-28T04:00:00Z Food and Drug Administration on Thursday approved a second drug that's part of a potent new class of medications that sharply cut levels of "bad" LDL cholesterol. FDA Approves Second Drug in New Class of Cholesterol-Lowering Medications 2015-08-27T04:00:00Z FDA officials said they approved Repatha for certain patients who are unable to control their LDL cholesterol with current treatment options. FDA approves Amgen cholesterol-lowering drug Repatha for some patients 2015-08-27T04:00:00Z This type of fat poses significant heart-health risks: For every 1 percent increase in energy from saturated fat intake, LDL cholesterol concentration, the undesirable type of cholesterol, increases by about 2 percentage points. 5 Dietary Guidelines for a Healthy Heart 2015-08-11T04:00:00Z However, high LDL cholesterol, while harmful over many years, is symptomless and the FDA was concerned that patients would either misdiagnosis themselves or not be motivated to get their blood tested in the first place. Pfizer Pulls The Plug On OTC Lipitor And It's The Patients' Fault 2015-07-29T04:00:00Z Participants given Praluent saw a reduction in LDL cholesterol ranging from 36 percent to 59 percent, the FDA said. Praluent Approved to Treat High Cholesterol 2015-07-27T04:00:00Z "The clinical studies we've done to date really have shown exactly what we've hoped for, which is a truly unprecedented ability to lower LDL cholesterol," he said. FDA approves breakthrough cholesterol drug, but only for certain high-risk patients 2015-07-24T04:00:00Z One recent review of 24 clinical trials -- published in the Annals of Internal Medicine -- found that PCSK9 inhibitors lowered people's LDL cholesterol by about 47 percent, on average. FDA OKs First of New Class of Cholesterol Drugs 2015-07-24T04:00:00Z That contributed to an unprecedented low level of LDL cholesterol as well. This New FDA-Approved Cholesterol Drug Is a Game Changer 2015-07-24T04:00:00Z Advocates say the new drugs fill a need for some of the estimated 73 million Americans who suffer from high LDL cholesterol. New cholesterol-lowering medications likely to trigger fight over prices 2015-07-21T04:00:00Z The new guidelines focus more specifically on the use of statins -- drugs such as Crestor, Lipitor and Zocor -- to prevent heart disease by lowering "bad" LDL cholesterol. Wider Use of Statin Drugs Could Save Thousands More Lives: Report 2015-07-14T04:00:00Z Saturated fat increases levels of LDL cholesterol, which are associated with higher rates of heart disease—but saturated fat also seems to raise HDL cholesterol, which might help ease those effects. Should I Eat Butter? 2015-06-18T04:00:00Z However, it has been found that PHOs turn into sludge in arteries, lowering “good” HDL cholesterol and raising “bad” LDL cholesterol, leading to heart attacks, strokes and other serious health problems. FDA bans trans fats in the U.S.: Which foods have them 2015-06-16T04:00:00Z They homed in on those with the highest and lowest levels of LDL cholesterol, and sequenced their genomes to see if any patterns emerged. This New FDA-Approved Cholesterol Drug Is a Game Changer 2015-07-24T04:00:00Z Consuming trans fats simultaneously increases "bad" LDL cholesterol and drives down "good" HDL cholesterol in a person's bloodstream. FDA Tells Food Industry to Stop Using Artificial Trans Fats 2015-06-16T04:00:00Z Studies have consistently found that elevated levels of LDL cholesterol are a major risk factor for heart disease and that risk drops in lock step with declines in LDL. Panel Tells F.D.A. to Back Second Drug to Help Heart 2015-06-10T04:00:00Z Praluent works by blocking a protein called PCSK9 that normally stops the liver from being able to fully clear LDL cholesterol from the bloodstream. FDA panel recommends approving new drug that dramatically lowers cholesterol 2015-06-09T04:00:00Z Further studies of the drugs that mimicked the effect of the genetic mutation showed that almost everyone taking them enjoyed a drop in LDL cholesterol levels of up to 65%. The Next Big Drug to Treat Heart Disease 2015-06-09T04:00:00Z A recent review of 24 clinical trials -- published April 28 in the Annals of Internal Medicine -- found that PCSK9 inhibitors lowered people's LDL cholesterol by about 47 percent, on average. FDA Advisers Weigh 2 New Cholesterol Drugs 2015-06-09T04:00:00Z People who have taken them have seen their LDL cholesterol, the so-called bad cholesterol, plunge to remarkably low levels. Federal Panel Weighs Approving Two New Cholesterol Drugs 2015-06-09T04:00:00Z The excitement is being generated by the powerful LDL cholesterol lowering properties of these drugs. For The Pricing Of New Cholesterol Lowering PCSK-9 Drugs, Does Dose Size Matter? 2015-06-01T04:00:00Z Both drugs belong to a new class of antibodies that target PCSK9, a protein that maintains "bad" LDL cholesterol in the blood, and are aimed at the millions of people who don't benefit from statins. Fight over hot new cholesterol drugs may be won in milligrams 2015-05-26T04:00:00Z Fonarow cautioned that researchers also haven't proven that lowering triglycerides -- but not "bad" LDL cholesterol -- will lower the risk of heart problems. Americans' Blood Triglyceride Levels Dropping: CDC 2015-05-07T04:00:00Z The review of 24 clinical trials found that PCSK9 inhibitors lowered people's LDL cholesterol by about 47 percent, on average. New Drug Class Slashes 'Bad' Cholesterol, Review Finds 2015-04-27T04:00:00Z Lowering LDL cholesterol has generally been found to protect against heart disease. Federal Panel Weighs Approving Two New Cholesterol Drugs 2015-06-09T04:00:00Z For obvious reasons, he kept himself in reasonably good shape, tried to eat well, kept his weight down and took a statin to keep his LDL cholesterol below 100. Mark Cuban -- Health Guru Or Irresponsible Billionaire? 2015-04-06T04:00:00Z Both lowered LDL cholesterol powerfully, which is what the drugs were designed to do. New Cholesterol Drugs: Highly Effective But Important Questions Remain 2015-03-15T04:00:00Z However, coffee may increase LDL cholesterol, affect pregnancy outcomes and increase anxiety and blood pressure, Heller said. Love Coffee? Your Heart May, Too 2015-03-02T05:00:00Z Most patients saw significant decreases in LDL cholesterol. Poor Response to Statins May Mean Clogged Arteries 2015-02-26T05:00:00Z LDL cholesterol levels plunge by about 40 to 65 percent, even if the starting level was achieved with a statin, the mainstay drug for cholesterol lowering first introduced in the late 1980s. Federal Panel Weighs Approving Two New Cholesterol Drugs 2015-06-09T04:00:00Z Most of the variants involved logical processes such as the formation of HDL and LDL cholesterol, triglycerides and processing of insulin. The Future of Obesity Treatment Could Get Personal 2015-02-11T05:00:00Z Studies also show that people who add beans to their diet lower heart-harmful LDL cholesterol in a matter of weeks. 5 Foods That Won’t Break Your Heart 2015-02-10T05:00:00Z But anacetrapib is lowering LDL cholesterol via a new, undefined mechanism and its relevance to cardiovascular medicine remains to be proven. Forget HDL, Merck Is Banking On LDL For Its Heart Drug, Anacetrapib 2015-02-05T05:00:00Z Fonarow said new drugs to lower LDL cholesterol are being tested in large clinical trials. Poor Response to Statins May Mean Clogged Arteries 2015-02-26T05:00:00Z They defined high cholesterol very conservatively in this study, pegging it at about 130 mg/dL of "bad" LDL cholesterol, a level which the U.S. Prolonged High Cholesterol in Middle Age Raises Heart Risk Later: Study 2015-01-26T05:00:00Z The drug, alirocumab, belongs to an emerging class of injectable drugs that block a naturally occurring protein called PCSK9, which inhibits the liver from expelling "bad" LDL cholesterol. UPDATE 2-Sanofi, Regeneron cholesterol drug also effective in monthly doses 2015-01-09T05:00:00Z Do the actions we recommend above, and also strive for normal blood pressure and LDL cholesterol levels. Why Rationing Preventive Services By Age is a Mistake 2014-12-08T05:00:00Z They are resting all their hopes on the enhanced LDL cholesterol lowering capacity of anacetrapib which, when combined with a statin, is superior to a statin alone. Forget HDL, Merck Is Banking On LDL For Its Heart Drug, Anacetrapib 2015-02-05T05:00:00Z However, for 20 percent of the patients, LDL cholesterol levels either decreased only a little, remained the same or increased. Poor Response to Statins May Mean Clogged Arteries 2015-02-26T05:00:00Z This trial's finding that alirocumab was more effective at lowering LDL cholesterol than Zetia is particularly interesting given the results of another study -- also presented Monday -- on Zetia combined with a statin. Experimental Cholesterol-Lowering Drug Effective, Study Reports 2014-11-17T05:00:00Z A very large genetic study published in the New England Journal of Medicine offers compelling evidence in support of a central role for LDL cholesterol in coronary heart disease. Newly Identified Gene Mutations Act Like a Lifetime of Treatment with Merck Cholesterol Drug 2014-11-13T05:00:00Z Researchers found that people with rare mutations that switch off a single copy of a gene called NPC1L1 are protected against high levels of "bad" LDL cholesterol and narrowing of the heart's arteries. Researchers Find Gene Mutation That May Protect Against Heart Disease 2014-11-12T05:00:00Z Theoretically, this added boost in lowering LDL cholesterol should in turn reduce cardiovascular events. Forget HDL, Merck Is Banking On LDL For Its Heart Drug, Anacetrapib 2015-02-05T05:00:00Z Now, however, a new genetic study published in JAMA suggests that LDL cholesterol may in fact cause an increase in aortic valve calcium and aortic valve stenosis. Genetic Study Suggests Possible Causal Role for Cholesterol In Heart Valve Disease 2014-10-26T04:00:00Z Zetia prevents absorption of LDL cholesterol in food by the intestines. Experimental Cholesterol-Lowering Drug Effective, Study Reports 2014-11-17T05:00:00Z So IMPROVE-IT will provide vital new raw material to the debate about the reliability of surrogate endpoints in general and the independent importance of lowering LDL cholesterol in particular. Cholesterol Drugs Haunted By Ghosts Of Past, Present, And Future 2014-10-02T04:00:00Z So far, more than half of the people in the program who started off with above-normal blood pressure have lowered it significantly, and those with high LDL cholesterol levels have seen reductions averaging 15 points. Hospital of Tomorrow Will Be 'Dynamic System' 2014-09-09T04:00:00Z People in the low-carb group ate more monounsaturated fat and even more saturated fat than they did before their diet, but still saw a drop in LDL cholesterol. For Weight Loss, Low-Carb Diet Beats Low-Fat 2014-09-01T04:00:00Z Select products that contain no trans fats, which raise levels of bad LDL cholesterol and lower levels of good HDL cholesterol, Blakely added. Read Food Labels to Combat Childhood Obesity 2014-08-22T04:00:00Z It improves the removal of LDL cholesterol from the bloodstream by blocking a protein that normally stops the body from getting rid of LDL, according to the researchers. Experimental Cholesterol-Lowering Drug Effective, Study Reports 2014-11-17T05:00:00Z Compounds called cafestol, present in coffee beans, appear to raise LDL cholesterol—though paper filters eliminate most of those compound, making it more of a concern with French press and espresso-style brews. Is Coffee Bad for You? 2014-08-20T04:00:00Z It is widely believed that the trial will provide a significant contribution to the debate about the reliability of surrogate endpoints in general and the independent importance of lowering LDL cholesterol in particular. IMPROVE-IT Trial Scheduled For Presentation In November 2014-08-12T04:00:00Z Dr. Williams became a vegan in 2003 because he was concerned that his LDL cholesterol — the kind associated with an increased risk of heart disease — was too high. Advice From a Vegan Cardiologist 2014-08-06T04:00:00Z There’s more than one type of cholesterol: Low-density lipoprotein or LDL cholesterol is the bad guy. Keeping Your Cholesterol in Check 2014-07-30T04:00:00Z For example, use of cholesterol-lowering medications increased from just under 4 percent to nearly 13 percent over time in these patients, with an accompanying decline in "bad" LDL cholesterol levels. Stroke Rates Declining Among Seniors, Study Shows 2014-07-15T04:00:00Z Low-density lipoprotein, or LDL cholesterol, targeted by changes in diet and popular statin drugs, remains public enemy number one. Mutations That Prevent Heart Attacks Upend The Search For New Drugs 2014-06-19T04:00:00Z The American Academy of Pediatrics released guidelines a number of years ago recommending that children as young as 8 years old be treated with medication for an LDL cholesterol level above 190. Calling an Ordinary Health Problem a Disease Leads to Bigger Problems 2014-06-02T04:00:00Z The next big price battle centers on a new class of cholesterol drugs known as PCSK9 inhibitors, which help the liver to clear “bad” LDL cholesterol from the blood. Insurers scrutinize drug costs after $84,000 Sovaldi surprise 2014-05-28T04:00:00Z The antibodies in evolocumab are designed to intercept PCSK9, preventing the protein from breaking down the cells' LDL receptors, which allows them to stay in circulation longer to remove LDL cholesterol, she explained. New Drug May Help Lower 'Bad' Cholesterol Beyond Statins 2014-05-13T04:00:00Z Under the earlier guideline statins were indicated for primary and secondary prevention based largely on LDL cholesterol levels. 12.8 Million More Adults Now Eligible For Statin Therapy 2014-03-19T21:08:00Z In addition to raising LDL cholesterol, saturated fat also increases high-density lipoprotein, or HDL, the so-called good cholesterol. Well: Study Questions Fat and Heart Disease Link 2014-03-17T21:11:51Z Another idea is that it increases unhealthy blood fats like triglycerides and “bad” LDL cholesterol levels, while decreasing “good” HDL cholesterol. More Evidence That Sugar Is Harming Our Hearts 2014-02-04T02:02:00Z The RUTHERFORD-2 study included patients with familial hypercholesterolemia, an inherited condition that causes high levels of "bad" LDL cholesterol starting at birth. Amgen's cholesterol fighter succeeds in fifth late-stage study 2014-01-30T22:45:17Z Compared with the placebo, evolocumab taken every two weeks reduced LDL cholesterol levels an additional 66 percent to 75 percent, and taken monthly cut the level by 63 percent to 75 percent. New Drug May Help Lower 'Bad' Cholesterol Beyond Statins 2014-05-13T04:00:00Z Evolocumab belongs to a class of medicine called PCSK9 inhibitors that work by blocking a protein that reduces the liver's ability to remove LDL cholesterol from the blood. Amgen cholesterol drug meets goal of third late stage trial 2014-01-23T17:05:12Z And soluble fiber, found in many red fruits, helps lower "bad" LDL cholesterol. Your Plan for a More Colorful Year 2014-01-08T15:28:00Z It was not associated with increases in triglycerides, glucose or LDL cholesterol levels, which are also risk factors for cardiovascular disease. Well: Idea of Healthy Obesity Is Tested 2013-12-09T21:18:37Z On average, 62 percent of the fat in nuts is monounsaturated, the kind that supports healthy levels of protective HDL cholesterol and does not raise blood levels of harmful LDL cholesterol. Well: Snacking Your Way to Better Health 2013-12-09T05:02:41Z Cells primarily located in the liver contain receptors that target LDL cholesterol and remove it from the bloodstream. New Drug May Help Lower 'Bad' Cholesterol Beyond Statins 2014-05-13T04:00:00Z Infections were the most frequently reported adverse side effects, as well as increases in "bad" LDL cholesterol and transaminases, they added. Sanofi, Regeneron arthritis drug meets goals in Phase 3 trial 2013-11-22T06:34:05Z Several companies are developing the drugs, which work by blocking a protein that prevents the liver from removing LDL cholesterol from blood. Amgen cholesterol drug appears safe, cut LDL 52 percent at 1 year: study 2013-11-19T23:25:29Z The guidelines no longer focus mainly on reducing the level of "bad" LDL cholesterol to specific targets, but instead assess each patient's personal risk factors of developing heart disease. Heart guidelines authors defend method of calculating risk 2013-11-18T19:58:57Z Vytorin lowers LDL cholesterol but no one knows if it improves outcomes. The Fate Of New Cholesterol Drugs Depends On IMPROVE-IT 2013-11-15T11:09:00Z Those concerns emerged earlier this week when two leading U.S. medical organizations recommended that doctors drop their emphasis on specific targets for lowering "bad" LDL cholesterol levels. FDA says new cholesterol drugs may not need outcome studies 2013-11-15T00:33:36Z “We were unable to find solid evidence to support continued use of specific LDL cholesterol or non-HDL treatment targets,” said Stone. After Long Wait, Updated US Cardiovascular Guidelines Now Emphasize Risk Instead Of Targets 2013-11-12T21:00:00Z They write that their findings raise the possibility that statins may reduce not only LDL cholesterol and arterial inflammation, but may also reduce non-arterial inflammation in “inflamed tissues such as the periodontium.” News From Our 'Statin Civilization': High-Dose Statins Found To Reduce Gum Disease Inflammation 2013-10-02T19:30:00Z The drugs are self-injectable, man-made antibodies targeting a protein that prevents the body from eliminating "bad" LDL cholesterol from the bloodstream. Sanofi cholesterol drug touted as potential $3 billion blockbuster 2013-09-25T15:53:05Z Asked by Mark Willenbring • 58 votes A There is a focus on inflammation as another possible factor in the pathway to heart disease, but that does not mean LDL cholesterol is less important. Well: Ask Well: Calcium, Inflammation and Heart Disease 2013-07-12T18:44:17Z One is from large clinical trials of statins, which included women, and found that, just as in men, reducing LDL cholesterol with statins reduced the risk of heart attacks and deaths from cardiovascular disease. Well: Ask Well: Women and Statins 2013-07-11T16:35:28Z The authors suggest that low LDL cholesterol may be a marker for preclinical cancer. Mouthwash as an acne treatment 2013-05-23T00:38:07Z There was no difference in LDL cholesterol between the phytosterol or placebo groups at three months, six months or one year, according to the study published in the American Heart Journal. Combined supplements no better for cholesterol 2013-05-16T17:44:57Z “The major determinant of blood LDL cholesterol is saturated fat,” Lichtenstein says. Eggs, even with their cholesterol, are a good source of protein for most people 2013-05-13T18:50:44Z Researchers with health laboratory giant Quest Diagnostics took a closer look at LDL cholesterol, the so-called bad kind. Study: Cholesterol progress stalled in recession 2013-05-10T21:02:11Z “Liptruzet is a combination of two currently marketed drugs that effectively lower elevated levels of LDL cholesterol,” she said. F.D.A. Approves Merck’s Combination Drug to Reduce Cholesterol 2013-05-04T00:49:45Z Lowering LDL cholesterol, some doctors asserted, might not prevent heart attacks. Merck's Cholesterol Pill Win Is Already Drawing Fire 2013-05-03T21:59:54Z Further, these screening tests focus on the measurement of LDL cholesterol. WSJ Article Fails To Raise Key Questions About Cardiovascular Risk In Children 2013-04-30T19:37:57Z Her team had been following families with a genetic form of extremely high levels of LDL cholesterol known as familial hypercholesterolaemia, which leads to severe coronary artery disease and, often, premature death. Genetics: A gene of rare effect 2013-04-10T17:20:29.100Z “The physician screening rates for tests other than LDL cholesterol were less than exemplary and are a substantial health promotion opportunity both for physicians and their patients,” the authors write. Healthy Docs Make Healthy Patients 2013-04-09T09:10:00Z The particularly large improvement in control of LDL cholesterol was likely caused by the availability and increased use of statins. Amid Rising Tide Of Diabetes More Patients Reach Treatment Goals 2013-02-15T21:23:22Z Zetia helps block absorption of "bad" LDL cholesterol in the intestines, and Zocor helps block production by the liver of LDL cholesterol. UPDATE 2-Merck to pay $688 mln to settle Enhance lawsuits 2013-02-14T15:22:15Z In patients who received the shot each month, the drug reduced LDL cholesterol by 42–50% at the end of 12 weeks compared to placebo. Drugs: Blood battles 2013-01-30T18:23:11.017Z Just 2% of all black people in the Dallas study had either of the two mutations — and those mutations were each associated with a 40% reduction of LDL cholesterol in the blood. Genetics: A gene of rare effect 2013-04-10T17:20:29.100Z These newly recruited monocytes enter the arterial wall and mature into macrophages, which gorge on LDL cholesterol and balloon in size. Pathology: At the heart of the problem 2013-01-30T18:23:07.253Z The drug also caused a slight increase in unhealthy LDL cholesterol. FDA advisory panel backs J&J diabetes drug approval 2013-01-10T22:43:26Z LDL cholesterol varied less than 10 percent, and triglycerides less than 20 percent. Vital Signs: Screening: Cholesterol Tests May Not Hinge on Fasting 2012-11-12T21:29:30Z There are several types of treatment under development to lower LDL cholesterol that work differently to statins. Drugs: Blood battles 2013-01-30T18:23:11.017Z It wasn't just that her LDL cholesterol measured 14. Genetics: A gene of rare effect 2013-04-10T17:20:29.100Z The trial results were in line with two other studies showing significant reductions in LDL cholesterol that were unveiled on Monday at the American Heart Association scientific meeting in Los Angeles. Amgen drug cuts bad cholesterol up to 66 percent in statin patients - trial 2012-11-06T17:57:14Z Patients receiving AMG 145 experienced an average reduction in LDL cholesterol after 12 weeks of 41 to 51 percent, depending on the dose. New Drugs for Lipids Set Off Race 2012-11-06T01:58:21Z Patients treated with a placebo saw a 1 percent increase in LDL cholesterol. Amgen experimental drug lowers cholesterol in mid-stage trial 2012-11-05T18:53:39Z Most of the patients studied were also being treated with statin drugs to lower LDL cholesterol, as well as other medications to reduce risk after heart attack, such as aspirin, clopidogrel, and beta blockers. Dalcetrapib: Another HDL-Raising CETP Inhibitor Bites The Dust 2012-11-05T19:30:28Z How did the gene exert such profound effects on LDL cholesterol levels? Genetics: A gene of rare effect 2013-04-10T17:20:29.100Z Total cholesterol as well as LDL cholesterol levels were down, and levels of “good” HDL cholesterol were up. Healthier Cholesterol Levels Among U.S. Adults 2012-10-17T13:35:23Z LDL cholesterol is removed from the blood when it binds to LDL receptors on the surface of liver cells, and then is taken inside the cells. New Drugs for Lipids Set Off Race 2012-11-06T01:58:21Z Eating trans fat both raises LDL cholesterol and lowers HDL cholesterol. Cholesterol levels declining in U.S 2012-10-16T20:47:42Z FDA reviewers said that mipomersen was generally effective in lowering LDL cholesterol. FDA Review Raises Safety Concerns About Mipomersen 2012-10-16T16:26:32Z Patients on canagliflozin experienced modest increases in both bad LDL cholesterol and good HDL cholesterol. J&J diabetes drug effective in high risk patients - study 2012-10-02T10:00:49Z They looked at the average levels of the participants’ total cholesterol, “bad” LDL cholesterol, “good” HDL cholesterol and artery-clogging triglycerides. Healthier Cholesterol Levels Among U.S. Adults 2012-10-17T13:35:23Z After six months, the apple-eaters saw their total cholesterol drop even further, to 13 percent less than what it was at the beginning of the study, and LDL cholesterol dropped by 24 percent. An apple a day keeps high cholesterol at bay? 2012-08-16T17:57:56Z Levels of "good" HDL cholesterol and "bad" LDL cholesterol and triglycerides improved too. Health Buzz: Kids' Cholesterol Levels Have Fallen 2012-08-08T13:38:00Z The levels of LDL cholesterol - also called "bad" cholesterol - and fats in the blood also fell among adolescents over the study, which is based on nationally representative data on more than 16,000 youths. Children's cholesterol improving slightly 2012-08-07T20:37:26Z The injectable drug works by blocking PCSK9, a naturally occurring protein that coaxes the body to hold onto "bad" LDL cholesterol. Sanofi eyes 2015 launch of novel cholesterol drug 2012-07-20T05:02:30Z In clinical trials, Tredaptive raised HDL levels by 20 percent, while cutting "bad" LDL cholesterol by 18 percent. Merck osteoporosis drug, company pipeline win more respect 2012-07-12T20:07:24Z Additionally, while the group of women who ate apples saw LDL cholesterol reductions over time, those reductions resulted in levels that ended up to be no different than those of the women who ate prunes. An apple a day keeps high cholesterol at bay? 2012-08-16T17:57:56Z The effects were somewhat stronger among those taking simvastatin, which also accounted for a greater reduction in LDL cholesterol. Statin drugs may make users feel fatigued 2012-06-18T18:03:10Z My doctor recommended niacin since the bad LDL cholesterol is fine but the good HDL is too low. People's Pharmacy: Generic drug is matter of life or death 2012-04-04T20:59:04Z Found in partially hydrogenated vegetable oil, it both increases LDL cholesterol and decreases HDL cholesterol. It?s smart to limit calories that come from fat, especially saturated fat 2012-03-05T19:48:10Z While it's always been smart to ditch the butter and forget the fatty meats, recent research suggests opting for plant-based foods is an effective way to lower the level of LDL cholesterol. Health Buzz: FDA Adds Warnings to Statins 2012-02-29T14:51:00Z These findings are bolstered by results from clinical trials demonstrating that nuts lower LDL cholesterol levels, the kind associated with an increased risk of heart disease. Foods that are good?and bad?for your heart 2012-02-07T00:33:00Z At one year, compared to placebo, LDL cholesterol was 26 percent lower in patients who received simvastatin and 38 percent lower in patients who received VYTORIN. FDA Rejects Proposed Chronic Kidney Disease Indication for Vytorin 2012-01-25T18:02:57Z It's known that industrial trans fats tend to raise people's levels of LDL cholesterol, while also lowering HDL cholesterol -- a double whammy against heart health. Natural trans fat may not boost "bad" cholesterol 2012-01-11T17:26:19Z Cholesterol is an exception — a standard optimal range is used for LDL cholesterol. What's normal for blood work? 2011-11-28T20:45:05Z LDL cholesterol is considered optimal when it is below 100 milligrams per deciliter, whereas 160 mg/dL or more is considered high. Green tea shows small effect on cholesterol 2011-11-16T17:16:27Z Subjects assigned to eat oat cereal every day lowered their total and LDL cholesterol levels seven or eight points more than those on a diet of refined grains. Foods that are good?and bad?for your heart 2012-02-07T00:33:00Z "The majority of studies support the concept that palmitic acid in palm oil raises LDL cholesterol," Clifton wrote in an editorial that accompanied Tholstrup's study in the American Journal of Clinical Nutrition. Palm olein may be less heart-friendly than thought 2011-11-15T21:20:10Z Statins are drugs that inhibit the natural ability of our body to generate cholesterol and result in the reduction of LDL cholesterol in the blood. Cholesterol and Controversy: Past, present, and future 2011-11-15T16:15:00.277Z "Cheese lowers LDL cholesterol when compared with butter intake of equal fat content and does not increase LDL cholesterol compared with a habitual diet," wrote Julie Hjerpsted and her colleagues, from the University of Copenhagen. Is cheese better than butter for heart health? 2011-11-15T02:47:19Z Looking at 20 past clinical trials, researchers found that green tea trimmed 5 to 6 points more from people's total cholesterol and "bad" LDL cholesterol levels than dummy capsules or other inactive treatments. Green tea shows small effect on cholesterol 2011-11-16T17:16:27Z The drug drives "bad" LDL cholesterol to lower levels than prior treatments, proving in study after study that it cuts the risk of heart attack and stroke. Analysis: Lipitor, legendary cash cow, prepares for fadeout 2011-11-06T17:56:27Z High levels of LDL cholesterol, as opposed to high-density lipoprotein, or HDL, cholesterol, are considered bad for people's cardiovascular health. Palm olein may be less heart-friendly than thought 2011-11-15T21:20:10Z It found that the higher the woman's intake of trans fats -- which raise "bad" LDL cholesterol, but also lower heart-healthy HDL cholesterol -- during the second trimester of pregnancy, the larger her newborn was. More trans fat in pregnancy tied to bigger baby 2011-10-13T03:36:23Z Trans fats are considered particularly unhealthy because they not only raise "bad" LDL cholesterol, but also lower heart-healthy HDL cholesterol. More trans fat during pregnancy tied to bigger baby 2011-10-12T17:21:24Z Those who played soccer reduced their body fat and and LDL cholesterol. Pick-Up Soccer Helps Homeless Health 2011-10-11T17:45:05.447Z Saturated fat, for example, generally increases levels of LDL cholesterol. Health Buzz: Denmark Imposes 'Fat Tax' 2011-10-03T15:30:00Z Saturated fat raises total and "bad" LDL cholesterol levels, increasing the risk for heart disease. Greek Yogurt Vs. Regular Yogurt: Which Is More Healthful? 2011-09-30T20:02:00Z Lipitor and other current top-selling cholesterol drugs work instead by lowering "bad" LDL cholesterol. Roche expects $10 billion sales for HDL drug 2011-09-23T17:54:15Z People with high levels of LDL cholesterol, considered the bad type. A better option for low-cholesterol diets 2011-08-29T18:36:27Z They work by blocking PCSK9, a protein whose natural function is to preserve levels of "bad" LDL cholesterol in the bloodstream. Insight: Next big drug against cholesterol takes shape 2011-08-26T17:01:57Z I guess if I drink instant coffee, I'm raising my LDL cholesterol. People's Pharmacy: Will instant coffee raise cholesterol? 2011-06-15T21:36:04Z The AIM-HIGH trial using Abbott’s drug Niaspan in conjunction with a statin that lowers LDL cholesterol—LDL “bad,” HDL “good,” probably a macro in some health reporters’ laptops—showed that the drug worked as billed. The HDL Conundrum: What's Bad about Drugs for Good Cholesterol? 2011-05-27T19:45:00.233Z LDL cholesterol is the main source of artery clogs. NIH stops study of B vitamin to prevent heart attack 2011-05-26T16:01:09Z And in healthy human subjects, just 5 days of bed rest has been shown to result in increased plasma triglycerides and LDL cholesterol, as well as increased insulin resistance – all very bad things. Can sitting too much kill you? 2011-01-06T16:15:00.237Z But cutting LDL cholesterol remains the most proven way of reducing heart attacks and stroke, and is the industry's prime focus. Insight: Next big drug against cholesterol takes shape 2011-08-26T17:01:57Z Any fiber-rich food - including whole grains, beans and produce - slightly lowers LDL cholesterol. Consumer Reports Insights: Statins are potent drugs, but they carry risks 2010-12-06T21:46:00Z The culprit is LDL cholesterol—low-density lipoproteins, the bad kind—in their blood. Lowering LDL Cholesterol 2010-11-17T19:00:00Z Then physicians came to believe statins could also reduce the risk of a first heart attack in people who have high LDL cholesterol but are nonetheless healthy. Statins: The answer or false hope? 2010-08-11T17:39:00Z It's a significant issue: A study published Aug. 2 in the Annals of Internal Medicine found that consistently high levels of LDL cholesterol levels throughout early adulthood can lead to later development of heart disease. Cholesterol screening lacking for the young 2010-08-10T16:27:00Z The drug, mipomersen, is designed to lower "bad" LDL cholesterol in patients with severely high cholesterol. Safety is key for upcoming Isis cholesterol data 2010-08-01T16:34:00Z But researchers made a surprising discovery: for those with rock-bottom levels of LDL cholesterol induced by high-dose statin therapy, high HDL levels don't seem to matter. Some on Statins May Not Need Boost in 'Good' Cholesterol 2010-07-22T13:00:00Z The effect was most pronounced among people with higher LDL cholesterol to begin with and among those who were not obese. Vital Signs: Nutrition: Study Finds Eating Nuts Helps Cholesterol 2010-05-17T16:09:00Z Regeneron on Wednesday said two other drugs in earlier-stage trials significantly cut levels of "bad" LDL cholesterol and eased knee pain from osteoarthritis. Exclusive: Biotech Regeneron on verge of big leagues 2010-05-12T16:40:00Z Both groups showed declines in levels of harmful LDL cholesterol and increases in levels of heart-healthy HDL cholesterol. High-protein low-carb diet an option in obese teens 2010-04-01T19:25:00Z Reducing high LDL cholesterol levels with drugs, diet and other lifestyle changes is an important step in trying to prevent heart attacks and strokes. Doctors fail to cut cholesterol enough 2010-03-11T00:13:00Z In many patients, the drug reduced LDL cholesterol levels to the low levels seen among Aboriginal populations, but not usually seen among people in developed countries, the researchers noted. Some on Statins May Not Need Boost in 'Good' Cholesterol 2010-07-22T13:00:00Z |
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