| 单词 | immunosuppressive |
| 例句 | An editorial in the medical journal said that Tut’s “inherited conditions” led to “an inflammatory, immunosuppressive and constitutionally weakened condition.” Exhibition Review: King Tut Reigns at the Discovery Center and the Met 2010-04-22T22:18:00Z Macrophages were not the only immune cells affected; while the proliferation of T cells was unchanged, their antitumor activity was suppressed due to the immunosuppressive factors produced by senescent macrophages. Cancer stem cells trigger macrophage aging 2023-11-14T05:00:00Z The only cure has been a bone-marrow transplant, which requires finding a donor, undergoing intensive chemotherapy and taking immunosuppressive drugs. F.D.A. Experts Will Vote on Safety of a Cure for Sickle Cell Disease 2023-10-30T04:00:00Z "The protein is involved in the formation of immunosuppressive tumor microenvironments. Therefore, we found that our vaccine is much more effective at reducing metastasis, and not in reducing the growth of the primary tumors." Nanoparticle vaccine could curb cancer metastasis to lungs by targeting a protein 2023-10-18T04:00:00Z In the 1970s and 1980s advances in immunosuppressive drugs made the prospect of transplanting organs from other species more viable. No One Should Die Waiting for an Organ Transplant. These Doctors Want to Ensure That Doesn’t Happen 2023-10-19T04:00:00Z Both Bennett's and Faucette's procedures used standard immunosuppressive drugs in addition to an experimental one. Milestone Pig-to-Human Heart Transplant May Pave the Way for Broader Trial 2023-10-18T04:00:00Z "Our identification of specific cellular and molecular factors that can turn neutrophils into immunosuppressive and pro-tumoral agents in the TME opens the door to developing therapeutic approaches to make brain cancers more susceptible to immunotherapy." Study shows how brain tumors make certain immune cells turn traitor 2023-09-28T04:00:00Z This includes people taking immunosuppressive medications or those who have pre-existing conditions such as liver disease, cancer, HIV or diabetes. Flesh-eating bacteria infections are on the rise in the U.S. A biologist explains how to stay safe 2023-09-25T04:00:00Z Moreover, the activating small molecule used to bind the two pieces of the tool together is already being used as an anticancer and immunosuppressive drug. Split gene-editing tool offers greater precision 2023-09-21T04:00:00Z "She is the first patient in the UK who has had a kidney transplant to not require immunosuppressive medication after the surgery," he says. Girl receives UK's first rejection-free kidney from mum 2023-09-21T04:00:00Z All three patients were listed as candidates for lung transplants, an option doctors hope to avoid because patients require immunosuppressive drugs and often die within five to 10 years after transplant. An inside look at COVID's lasting damage to the lungs 2023-08-28T04:00:00Z Like other transplant patients, she needs to take immunosuppressive drugs to prevent tissue rejection. Woman 'joyous' after sister donates womb in UK first 2023-08-22T04:00:00Z The majority of people who shielded had a severe respiratory condition, were having immunosuppressive therapy or had cancer. Covid: No evidence shielding helped - Swansea uni study 2023-04-22T04:00:00Z Of the medical issues analyzed in the study, immunosuppressive conditions appeared to lead to the greatest increased risk of long Covid. Who Is Most at Risk for Long Covid? 2023-03-23T04:00:00Z But starting in October, they could apply for immunosuppressive drug coverage through a new benefit called Medicare Part B Immunosuppressive Drug , or Part B-ID, which started Jan. 1. What’s new for Medicare in 2023? 2023-02-02T05:00:00Z It is entirely my fault for not having this conversation earlier in the relationship, because I have lupus and am taking several immunosuppressive medications. Advice | Ask Amy: The man I’m dating isn’t vaccinated against the coronavirus 2022-08-09T04:00:00Z People with diabetes, excessive alcohol use, chronic lung disease, chronic kidney disease and immunosuppressive conditions are more susceptible to the bacteria. Potentially Deadly Bacteria Detected in U.S. Soil for First Time 2022-07-27T04:00:00Z For example, someone with rheumatoid arthritis may be prescribed methotrexate as a standard immunosuppressive treatment. Federal government warns rebel pharmacists who refuse to fill abortion-related prescriptions 2022-07-16T04:00:00Z Transplanted organs must be matched by their MHC molecules and, with the use of immunosuppressive drugs, can be successful even if an exact tissue match cannot be made. Anatomy and Physiology 2013-06-19T00:00:00Z This benefit covers only continuous immunosuppressive drugs, and these beneficiaries cannot have other health coverage. What’s new for Medicare in 2023? 2023-02-02T05:00:00Z “The death was reported in a 40-year-old patient who had underlying co-morbidity and was on immunosuppressive medications,” the Nigeria CDC said. First monkeypox death in Nigeria in 2022; 21 cases confirmed 2022-05-30T04:00:00Z If the hypothesis is confirmed—and Brodin stresses it has not been—he says immunosuppressive therapy would be appropriate. What’s sending kids to hospitals with hepatitis—coronavirus, adenovirus, or both? 2022-05-19T04:00:00Z One such immunosuppressive drug, rituximab, “knocks out your ability to make antibodies against new viral exposures and impairs your ability to make a response to a vaccine,” he says. How to Make Smart Decisions About COVID Risk-Benefit 2022-04-19T04:00:00Z The trigger for these diseases is, more often than not, unknown, and the treatments are usually based on resolving the symptoms using immunosuppressive and anti-inflammatory drugs such as steroids. Anatomy and Physiology 2013-06-19T00:00:00Z The medical team plan to wean Easton off the immunosuppressive drugs at some point, to see how he progresses. Revolutionary heart-thymus combined transplant success 2022-03-08T05:00:00Z Someone who has cancer like lymphoma and doesn’t respond well to the coronavirus vaccine, for example, is likely at higher risk than someone on an immunosuppressive drug for something like Crohn’s disease. For many immunosuppressed, churches stopped being a safe place 2022-02-27T05:00:00Z "I know my normal is never going to be normal," said Chris Neblett, 44, of Indiana, Pennsylvania, a kidney transplant recipient who takes immunosuppressive drugs to prevent his body from rejecting his transplanted organ. Covid still threatens millions of Americans. Why are we so eager to move on? 2022-02-22T05:00:00Z Also, I wanted to quickly find out whether I was infected because I take an immunosuppressive drug, making me more vulnerable to the coronavirus. Opinion | My epic, infuriating quest for a covid test 2021-12-27T05:00:00Z However, older individuals and those with suppressed immune responses due to disease or immunosuppressive drugs may respond even to short-term stressors by getting sicker more often. Anatomy and Physiology 2013-06-19T00:00:00Z But with other drugs for which treatment cannot be easily interrupted, like blood thinners and immunosuppressive medications, patients may need to adjust their dosage or be monitored while on Pfizer’s treatment. Pfizer’s Covid Pill Works Well, Company Confirms in Final Analysis 2021-12-14T05:00:00Z “We need to carefully evaluate the trade-off between the burdens of diabetes and the potential complications from immunosuppressive medications.” A Cure for Type 1 Diabetes? For One Man, It Seems to Have Worked. 2021-11-27T05:00:00Z As with many organ transplants, the recipient must take immunosuppressive medications to help the body accept the new organ, which can cause diabetes or renal damage in the long-term. More women are giving birth after uterus transplants — and experts say they could even be put in men 2021-11-27T05:00:00Z My mother-in-law, who has lupus and is on immunosuppressive therapy, had recently received her 3rd COVID-19 vaccine, following the guidelines provided by the CDC. The pandemic has eroded our trust in doctors 2021-10-31T04:00:00Z Pathogens can produce immunosuppressive molecules that impair immune function, and there are several different types. Anatomy and Physiology 2013-06-19T00:00:00Z People who need immunosuppressive treatments will also be able to get their boosters earlier. Some Covid booster doses brought forward 2021-10-29T04:00:00Z The patient was 67 and was taking multiple immunosuppressive medications because of a serious underlying medical condition, L.A. What Colin Powell's death tells us — and doesn't — about COVID-19 and vaccines 2021-10-19T04:00:00Z In all, abou t a third of patients went into remission, rates similar to those seen with immunosuppressive medications. Targeted Treatments for Autoimmune Disease Make Progress 2021-09-20T04:00:00Z Receptors for testosterone are found on the surface of B and T cells, and the hormone is largely immunosuppressive. Why Nearly 80 Percent of Autoimmune Sufferers Are Female 2021-09-15T04:00:00Z The FDA last week authorized a third dose of the Pfizer-BioNTech and Moderna vaccines for people with fragile immune systems, including patients taking immunosuppressive drugs because of organ transplants or those receiving cancer treatment. Fears over rising illness and death from the delta variant fuel Biden administration push for boosters 2021-08-17T04:00:00Z Recipients must take immunosuppressive drugs for the rest of their lives to keep the immune system from attacking the transplanted organs. 296 people donate organs in first year of new consent law 2021-05-19T04:00:00Z Some of the weakened response appears to be related to certain immunosuppressive drugs, and potentially a commonly prescribed steroid. Coronavirus vaccines may not work in some people. It’s because of their underlying conditions. 2021-05-18T04:00:00Z It urges people taking immunosuppressive medications to discuss the need for personal protective measures with their health-care providers, even if they are fully vaccinated. CDC says fully vaccinated Americans can go without masks outdoors, except in crowded settings 2021-04-27T04:00:00Z But immunosuppressive steroids are a double-edged sword, Crum-Cianflone says, leaving the door open to other infections. Common fungus emerges as threat to hospitalized COVID-19 patients 2021-03-22T04:00:00Z And testosterone, Dr. Klein said, “is kind of beautifully immunosuppressive.” Women Report Worse Side Effects After a Covid Vaccine 2021-03-08T05:00:00Z He was undergoing treatment with immunosuppressive drugs when he fell ill, and, during his illness, he received multiple rounds of additional treatment, with remdesivir nonimmune gamma globulin, and with monoclonal antibodies. How Will the Coronavirus Evolve? 2021-02-19T05:00:00Z To keep his rogue immune system from killing him, the patient required an arsenal of immunosuppressive drugs. Dangerous new coronavirus strains may incubate in COVID-19's sickest 2021-01-30T05:00:00Z It is possible that patients with autoimmune conditions, and particularly those receiving immunosuppressive therapy, are particularly rigorous with infection prevention practices such as social distancing, wearing masks and hand washing. Does an Autoimmune Disorder Affect My Covid-19 Risks? 2020-11-18T05:00:00Z They’re usually used for things like chemotherapy or other immunosuppressive drugs, and they treat people who are especially vulnerable to the coronavirus. Virus surges complicate the distribution of scarce COVID-19 treatments 2020-11-19T05:00:00Z "The results of our study suggest that the anti-cancer ability of PDE5 inhibitors might be related to regulating immunosuppressive effects," they wrote. Erectile dysfunction drugs may help reduce early death from colon cancer, study finds 2020-08-25T04:00:00Z “We used a fairly standard immunosuppressive regimen and took these rejected lungs and showed that we could actually sustain them and make them better.” Daily briefing: How Vietnam managed zero deaths from coronavirus 2020-07-13T04:00:00Z To reduce the inflammation, doctors treated them with intravenous immunoglobulin and tocilizumab, an immunosuppressive drug typically used in treating rheumatoid arthritis. Doctors beware: Some young coronavirus patients seem well, then rapidly deteriorate, New York hospital warns 2020-06-03T04:00:00Z One of the main treatments is immunosuppressive therapies, drugs which reduce the strength of the body's immune system making it more susceptible to infections. 'I'm high risk but made a full recovery from coronavirus' 2020-05-30T04:00:00Z Currently, many cell-based therapies use donor cells, in which case patients must receive immunosuppressive treatments to prevent graft rejection. Parkinson’s disease grafts benefit from well-timed growth factor 2020-05-25T04:00:00Z Some seven of the patients were organ transplant recipients so they were on immunosuppressive treatment and 10 were on dialysis. Experimental coronavirus treatment leronlimab resulted in 'remarkable recoveries,' developer says 2020-05-01T04:00:00Z That afternoon, increasingly concerned about his lung inflammation, doctors tried an immunosuppressive medication, tocilizumab. 32 Days on a Ventilator: One Covid Patient’s Fight to Breathe Again 2020-04-26T04:00:00Z The physicians also used an immunosuppressive drug to suppress Padgett’s immune system, which was reacting in an out-of-control way to the virus. Doctor recovering from virus after being on ventilator 2020-04-13T04:00:00Z "In addition, obesity is also a risk for autoimmune disease and asthma," he said, pointing out that those at highest risk of serious illness are also those taking immunosuppressive drugs for chronic conditions. Coronavirus' frightening profile: Who is more likely to die from COVID-19? 2020-03-31T04:00:00Z "Hence, the reason why hydroxychloroquine, an immunosuppressive agent, is beneficial by two mechanisms suppressing the immune response," Grace added. Malaria drugs touted by Trump can work against coronavirus, top doc tells Laura Ingraham 2020-03-21T04:00:00Z Today Talbert, now 61, treats her psoriatic arthritis with the immunosuppressive drug Stelara, and she manages the residual pain with other medications. Is bias keeping female, minority patients from getting proper care for their pain? 2019-07-26T04:00:00Z People with lupus are indeed more susceptible to infection, especially if they’re taking immunosuppressive drugs. Can I Get My Anti-Vaxx Sister’s Kids Vaccinated? 2019-05-14T04:00:00Z Some medical professionals considered the biological hurdles of xenografting too difficult to surmount, especially with the relatively limited immunosuppressive drugs available at the time. Leonard Bailey, transplant surgeon who gave ‘Baby Fae’ a baboon heart, dies at 76 2019-05-16T04:00:00Z “It’s not without risk or caution that we use immunosuppressive therapies,” Dubal says “But they’ve proven very effective in certain conditions.” How Young Blood Rejuvenates an Old Animal's Brain 2019-05-14T04:00:00Z Transplant patients, because of the immunosuppressive drugs they must take, face increased risk of certain forms of cancers. Charity Tillemann-Dick, operatic soprano who drew life and music from transplanted lungs, dies at 35 2019-04-24T04:00:00Z Brown was given harsh immunosuppressive drugs of a kind that are no longer used, and suffered intense complications for months after the transplant. HIV is reported cured in a second patient, a milestone in the global AIDS epidemic 2019-03-04T05:00:00Z And those transplanted kidneys rarely last a lifetime of battering with immunosuppressive drugs. Scientists Are Teaching the Body to Accept New Organs 2019-01-22T05:00:00Z People who develop chronic GvHD are usually treated with immunosuppressive therapies such as steroids. Solving lymphoma’s stem-cell problem 2018-11-13T05:00:00Z Regulatory T cell Commensal microbes help to maintain a healthy immune system by producing molecules that regulate the activity of immunosuppressive regulatory T cells. Gut reaction 2018-11-06T05:00:00Z These molecules include immunosuppressive proteins that are targeted by checkpoint inhibitors such as nivolumab, as well as other signals that, in parallel, can maintain immunosuppression when one of the roadblocks is lifted. Immunotherapy offers a promising bet against brain cancer 2018-09-25T04:00:00Z He, too, received immunosuppressive drugs, but the treatment was much less intense, in line with current standards for transplant patients. HIV is reported cured in a second patient, a milestone in the global AIDS epidemic 2019-03-04T05:00:00Z If an attempt to wean patients from immunosuppressive drugs fails, they can get dialysis to cleanse their blood. Scientists Are Teaching the Body to Accept New Organs 2019-01-22T05:00:00Z She argued that experts should focus on the 55 million people at highest risk of active infection: young children with infected relatives, the severely malnourished, and people with H.I.V. or other immunosuppressive conditions. ‘Latent’ Tuberculosis? It’s Not That Common, Experts Find 2018-09-20T04:00:00Z T cells entering a glioblastoma will encounter a profoundly immunosuppressive microenvironment created by low oxygen and pH levels and immunosuppressive molecules. T cells engineered to home in on brain cancer 2018-09-04T04:00:00Z STAT3 is not only immunosuppressive, it also has a role in controlling the progression of cancer. Immunotherapy offers a promising bet against brain cancer 2018-09-25T04:00:00Z When T cell function declines, such as with increasing age or during use of immunosuppressive drugs, viral clearance is delayed. How the flu hijacks your body to make you feel so wretched 2018-02-16T05:00:00Z They had been long-term users of immunosuppressive drugs and had normal liver biopsies. Scientists Are Teaching the Body to Accept New Organs 2019-01-22T05:00:00Z They inhibit the abilities of tumor-infiltrating white blood cells and increase the abilities of immunosuppressive regulatory T cells. Can Pregnancy Help Scientists Better Understand Cancer? 2018-02-05T05:00:00Z Burlingham’s laboratory had been studying fetal immune responses as a means of finding ways to help organ-transplant recipients tolerate their new organs without relying on immunosuppressive drugs. Eye-opening picture of fetal immune system emerges 2017-06-13T04:00:00Z Because the transplanted cells were grown from stem cells taken from mice, the animals required just five days of immunosuppressive drugs to keep their bodies from rejecting the new tissue. Scientists create a part-human, part-pig embryo — raising the possibility of interspecies organ transplants 2017-01-26T05:00:00Z She developed a severe form of the disease 14 years ago and tried everything imaginable in conventional and alternative medicine without relief — specialized diets, immunosuppressive drugs, special clothing, bleach baths. New Drug for Severe Eczema Is Successful in 2 New Trials 2016-10-01T04:00:00Z But the damage caused by immunosuppressive drugs is cumulative and irreversible, and use over a decade or longer can cause significant damage. Scientists Are Teaching the Body to Accept New Organs 2019-01-22T05:00:00Z Glucocorticoids -- a form of steroids -- are powerful immunosuppressive drugs used to treat a variety of medical conditions that involve inflammation. Certain Steroids Raise Risk for Serious Staph Infections 2016-06-09T04:00:00Z A spokeswoman says the policy is based on the Centers for Disease Control and Prevention recommendations for protecting immunosuppressive patients. Why Many Hospitals Are Banning Flowers and Balloons 2016-06-06T04:00:00Z The study authors recommend further research to assess the value of maintenance immunosuppressive therapy alongside stem cell transplant. Stem Cell Transplants May Not Help Tough-to-Treat Crohn's, Study Says 2015-12-15T05:00:00Z It's possible that some melanomas may be present at the time of transplant and begin to spread aggressively when patients start taking immunosuppressive drugs, Robbins noted. Deadly Skin Cancer More Common in Organ Transplant Recipients: Study 2015-08-17T04:00:00Z And transplants with donor hands, developed over the past two decades, expose recipients to risky immunosuppressive therapy for life, the researchers said. Scientists Bioengineer First Artificial Animal Limb 2015-06-04T04:00:00Z While the immunosuppressive therapy fought the anemia, it left her vulnerable to infections and unable to attend school. Hill City teen returns to school after battling disease 2015-05-17T04:00:00Z Researchers created the same immunosuppressive conditions in macaque monkeys that a measles infection creates and found that the disease-fighting white blood cells basically forgot how to fight much of anything besides measles. Measles Vaccine Reduces Death From Other Infections Too -- By Preventing 'Immune Amnesia' 2015-05-08T04:00:00Z Cancer, infections and premature death are the result of the toxic nature of immunosuppressive drugs. Doctor Seeking To Perform Head Transplant Is Out Of His Mind 2015-02-26T05:00:00Z “Theoretically, treatment of the systemic inflammation and improvement of disease activity through the use of immunosuppressive medications should then decrease the development of atherosclerosis and the risk of heart disease,” Ogdie said. Psoriasis or Rheumatoid Arthritis Linked to Heart Risk 2014-11-06T05:00:00Z This meant there was no danger of rejection, so no need for immunosuppressive drugs used in conventional transplants. Man walks again after transplant 2014-10-20T04:00:00Z According to the new study, the virus "rewires" immune cells to reduce their function -- essentially performing the immune-squelching work that immunosuppressive drugs do. Hepatitis C Infection May Have 'Silver Lining' for Transplant Patients 2014-06-25T04:00:00Z It no longer does, Cigna said, because “Acthar Gel is significantly more expensive than conventional corticosteroid and immunosuppressive therapies but is not clinically superior for such indications.” A Drug’s Risks Are Left Out in Discussion of Questcor Deal 2014-06-12T04:00:00Z The immunosuppressive tumor microenvironment represents a major hurdle to cancer therapy. [Research Articles] Genetic Engineering of Hematopoiesis for Targeted IFN-{alpha} Delivery Inhibits Breast Cancer Progression 2014-01-01T19:25:08.567Z An indirect way of preventing antitumour T-cell responses is by the generation of an immunosuppressive environment. Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z One big challenge, the study found, was determining how to balance antiretroviral drugs that the patients took to combat HIV with the immunosuppressive drugs meant to thwart organ rejection. U.S. Congress Moves Closer to Lifting Ban on Transplanting Organs From HIV-Positive Donors 2013-07-19T17:30:00Z These data and others suggest that neurons are immunologically inert, thereby paving the way for the potential use of allogeneic TENGs without immunosuppressive therapy. Researchers Build New Bridges for Nerve Injury 2013-01-14T17:15:00.237Z Steroids, sometimes in combination with immunosuppressive medications, are often used to treat Crohn's disease. 4 Common Diarrhea Causes—and What to Do if You Get Sick 2012-09-07T20:15:00Z Since the iPS approach uses the patient's own cells, they avoid the need for immunosuppressive drugs. Stem Cells Move Into Prime Time 2012-06-18T19:50:06Z The advantage of using tissue grown from a patient's own cells is that there is no risk of organ rejection and hence no need for lifelong immunosuppressive drugs. Vein grown from stem cells saves 10-year-old girl 2012-06-13T23:12:24Z She has been off immunosuppressive drugs for seven months. Treatment Allows Drug-Free Transplant Patients to Elude Graft-versus-Host Disease 2012-03-07T23:45:00.213Z Despite some success, enhancing tumor antigen presentation, promoting a protective antitumor response, and overcoming the immunosuppressive tumor microenvironment pose considerable challenges that necessitate further improvements in vaccine design. [Research Articles] Simultaneous Targeting of Toll- and Nod-Like Receptors Induces Effective Tumor-Specific Immune Responses 2012-02-08T20:55:11.063Z Corticosteroids and immunosuppressive medications also are used to treat this condition. 4 Common Diarrhea Causes—and What to Do if You Get Sick 2012-09-07T20:15:00Z "So, as eating is claimed to be the source of PFCs and it is the source of the immunosuppressive PUFAs, the study proves nothing," he said. PFC chemicals tied to immune problems in kids 2012-01-24T22:34:17Z Then, in the 1970s, researchers trained rats and mice to associate a taste, such as sugar , with an immunosuppressive drug. Unusual Flavors Can Dampen Immune Response 2012-01-08T13:15:00.250Z Future models that test antitumor immunity should also consider the effects of multiple doses of chemotherapy administered with immunosuppressive medications to accurately model the delivery of chemotherapy in patients. [Perspective] Cancer: Autophagy in Tumor Immunity 2011-12-15T18:55:36.257Z “The myeloma cells are inducing the microenvironment to generate this immunosuppressive force field around them,” says Lee, who led the study. Microenvironment: Neighbourhood watch 2011-12-14T18:21:10.780Z No immunosuppressive drugs would be required for Schwann cell transplants, because the cells are from the patient’s own body. Preliminary Human Experiments to Test Safety of Paralysis Treatment Using Nerve Cells 2011-10-19T17:15:02.380Z More immunosuppressive drugs helped them adjust, he said, but the donated kidneys may wear out sooner, necessitating additional transplants. A New Push to Let H.I.V. Patients Accept Organs That Are Infected 2011-04-11T04:03:54Z Others have chosen to stay with a pump because they do not like the prospect of taking the immunosuppressive and other drugs that are standard for transplant recipients. Doctor's World: Pump Device Helps Cheney With Steady Pressure 2010-07-19T17:39:00Z He mentioned a study last year on mice that lived significantly longer after being given rapamycin, a and immunosuppressive drug. The New Landscape: Preparing to Care for an Aging Population 2010-06-28T21:07:00Z Those being treated for this condition with long-term immunosuppressive therapy should avoid using Depo-Provera, since both drugs can decrease bone density. How to Choose a Safe Birth Control Method: 11 Factors to Consider 2010-06-03T21:31:00Z |
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