| 单词 | antitoxin |
| 例句 | WHO purchases antitoxin, made in horses, from just two companies, and supply has been problematic for a decade. News at a glance: Diphtheria vaccine shortage, prisoner release, and iNaturalist’s growth 2023-09-20T04:00:00Z As diphtheria - a serious and sometimes fatal bacterial infection - spread among Nome's people, its port was icebound, meaning antitoxin would have to be delivered overland. A good dog with great genes - 1920s Alaska sled-relay hero Balto 2023-04-27T04:00:00Z In February 1925, in the midst of a diphtheria outbreak, a relay of sled dog teams delivered an emergency supply of antitoxin to Nome, Alaska, which had been isolated by snow. What Can You Do With a Menagerie of Mammal Genomes? 2023-04-27T04:00:00Z Dr. Park was responsible for helping mass-produce an antitoxin that served as a breakthrough in treating and preventing diphtheria, a disease that killed many of the small children and others who share his burial ground. Dancing Among Tombs on a Moonlit Brooklyn Night: ‘It Feels So Alive’ 2021-09-23T04:00:00Z So even if this approach works, patients will likely also need the approved antitoxin treatment to remove toxin from the blood. New strategy to fight world’s most potent poison passes first tests in animals 2021-01-06T05:00:00Z It has a case fatality rate of as high as 40% if not treated with antitoxin—supplies of which are “very constrained,” WHO reported. News at a glance: Diphtheria vaccine shortage, prisoner release, and iNaturalist’s growth 2023-09-20T04:00:00Z “Could there be anything such as a premature antidote to a poison? A premature antiseptic? A premature antitoxin? A premature anti-racist? If you were not premature, what sort of anti-fascist were you supposed to be?” The contested legacy of the anti-fascist International Brigades 2020-10-22T04:00:00Z Diphtheria antitoxin was especially persuasive that the germ theory was true. Opinion | Rushing convalescent plasma therapy for covid-19 isn’t wise 2020-08-27T04:00:00Z An unnamed ironist had appropriated a quotation from Mao about revolutionary war as “an antitoxin” that “eliminates the enemy’s poison” and offered it as a rebuke of the solemnity of Communist propaganda. Hong Kong’s Protest Movement and the Fight for the City’s Soul 2019-12-09T05:00:00Z By so doing, it would have prepared conditions for the third mutation—the one with the heftiest antitoxin effect. How Monarch Butterflies Evolved to Eat a Poisonous Plant 2019-10-02T04:00:00Z As the only source of botulism antitoxin in the United States, it also sends medicine for about 100 cases a year of severe food poisoning. Inside the secret U.S. stockpile meant to save us all in a bioterror attack 2018-04-24T04:00:00Z Science, in the form of powerful antitoxins and antibiotics administered by scientifically trained physicians, saved my life. Vaccinations: Science under attack 2018-04-20T04:00:00Z Watching a dying child recover after an injection of antitoxin is powerful evidence. Opinion | Rushing convalescent plasma therapy for covid-19 isn’t wise 2020-08-27T04:00:00Z The most famous of those missions was in 1925, when a relay of teams completed a “Serum Run” delivering a supply of antitoxin to Nome for children stricken by a diphtheria epidemic. Alaska's renowned Iditarod race, mired in controversy, to start... 2018-03-01T05:00:00Z Among those molecules were toxins and antitoxins; drugs to treat bacterial infections, malaria and heart ailments; anticarcinogens; and explosives. Isabella L. Karle, chemist who helped reveal structure of molecules, dies at 95 2017-10-20T04:00:00Z In the section of the warehouse where biologic drugs such as botulism antitoxins are stored at minus-4 degrees Fahrenheit, workers wear full-body insulated suits. Inside the secret U.S. stockpile meant to save us all in a bioterror attack 2018-04-24T04:00:00Z The gentlemen in Greenburgh on Monday also invoked all the correct balms, elixirs and antitoxins. At Knicks’ Facility, Hopeful Talk and Lessons Learned (or Maybe Not) 2017-07-17T04:00:00Z A more permanent solution now under study involves an injectable antitoxin vaccine. Wide Use of Antibiotics Allows C.Diff to Flourish 2015-05-25T04:00:00Z The most famous of those missions was in 1925, when a relay of teams completed a “Serum Run” delivering a supply of antitoxin to Nome for children stricken by a diphtheria epidemic. Alaska's renowned Iditarod race, mired in controversy, to start... 2018-03-01T05:00:00Z A botulism antitoxin arrived this week from the Centers for Disease Control and Prevention to treat those who are ill. Ohio: 26 people suspected of having botulism; 27th confirmed 2015-04-24T04:00:00Z On Monday, officials announced plans to add more anthrax antitoxin. Inside the secret U.S. stockpile meant to save us all in a bioterror attack 2018-04-24T04:00:00Z Officials said a botulism antitoxin arrived in Ohio earlier this week from the Centers for Disease Control and Prevention to treat those who are ill. Ohio woman who died after getting botulism identified 2015-04-24T04:00:00Z Trinity Hospital says the antitoxin to treat botulism costs about $50,000. Rare botulism case diagnosed at Minot hospital; patient OK 2015-03-27T04:00:00Z The idea of producing “artificial antibodies” traces back to the work of late 19th-century German physician Paul Ehrlich who first proposed that the immune system can neutralize toxins or pathogens by forming "antitoxins." A Pill That Mimics the Immune System 2015-02-09T05:00:00Z The journal plans to add the genetic sequence to the scientific record once an H antitoxin is developed. Botulism Bioterror Worries Keep Research under Wraps 2014-01-07T12:15:00.524Z The journal plans to add the sequence data to the scientific record later, once an H antitoxin is made. Researchers Keep Mum on Botulism Discovery 2013-10-22T10:45:00.560Z But the injection of antitoxin is a “surgical operation” and therefore not provided for by the annual fee. Dr. Grenfell's Parish The Deep Sea Fisherman 2012-03-15T02:00:30.867Z If you find a physician opposed to the use of antitoxin this simply means that he is a quack. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z Based on the idea he and his colleagues began developing drugs meant to function like these antitoxins, including one to treat Trypanosoma parasite infections. A Pill That Mimics the Immune System 2015-02-09T05:00:00Z If you do, it is sufficient evidence that you sadly need them; for they are the antitoxin to counteract the bacillus of pedantry. The Gentle Reader 2012-02-15T03:00:37.463Z The antitoxin has been found, and is applied successfully. A Ten Year War An Account of The Battle with The Slum in New York 2012-02-11T03:03:42.997Z The change in his blood which we effect by injecting antitoxin makes him temporarily safe against diphtheria. Human Personality and its Survival of Bodily Death 2012-01-05T03:00:42.307Z One serious disadvantage in the use of antitoxin is that it leaves the dangerous bacillus in the throat of the patient about as long as an unaided convalescence would leave it. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z Calcium gluconate and gas gangrene antitoxin as well as antibiotics are helpful. Natural History of Cottonmouth Moccasin, Agkistrodon piscovorus (Reptilia) 2011-12-17T03:00:17.963Z The value of antitoxin in the treatment of diphtheria. The Pros and Cons of Vivisection 2011-08-23T02:00:31.033Z The effect of the abnormal conditions is probably to stop the production of, or weaken or destroy the protective enzymes or antitoxins, the presence of which normally confers immunity on the leaf. Encyclopaedia Britannica, 11th Edition, Volume 11, Slice 3 "Frost" to "Fyzabad" 2011-08-15T02:00:28.473Z The treatment must be both general with antitoxin and local with antiseptics. Encyclopaedia Britannica, 11th Edition, Volume 10, Slice 1 "Evangelical Church Conference" to "Fairbairn, Sir William" 2011-07-16T02:00:16.387Z As to the use of antitoxin as a preventive and cure for diphtheria, too much praise cannot be given to that wonderful discovery. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z Place of Personal Influence.—When the antitoxins and directly curative serums seemed about to make for themselves a place in therapeusis, it looked for a time as though this personal element might be entirely superseded. Psychotherapy 2011-06-19T02:00:20.053Z There are substances in the fluid part of the blood which are called antitoxins, because they neutralise the toxins produced by the bacteria. The Pros and Cons of Vivisection 2011-08-23T02:00:31.033Z For in the minds of prisoners anti-bodies to the disease of pessimism multiply so fast that their combative antitoxin keeps pace with the worst of news. A Prisoner in Turkey 2011-05-28T02:00:23.023Z Here it is difficult to remove the cause, but many cases can be cured and almost all are alleviated be means of a special antitoxin applied locally. Encyclopaedia Britannica, 11th Edition, Volume 10, Slice 1 "Evangelical Church Conference" to "Fairbairn, Sir William" 2011-07-16T02:00:16.387Z The antitoxin produced in the contest of the body cells against some diseases will not only neutralise the toxin of a particular disease, but it will also neutralise the toxin of a second disease. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z Unfortunately, our further experience with antitoxins and therapeutic sera of various kinds has not been satisfactory, and now the medical world is looking elsewhere for progress in therapeutics. Psychotherapy 2011-06-19T02:00:20.053Z The marvellous part of the defence is that, although we all have a certain amount of antitoxin in our blood, the amount increases in proportion to the amount of toxin. The Pros and Cons of Vivisection 2011-08-23T02:00:31.033Z Because the antitoxin is known to sometimes cause a severe, even life-threatening allergic reaction, the patient was transferred to the I.C.U. for closer monitoring, and the botulism antitoxin was given. Well: Think Like a Doctor: A Toothache and Slurred Speech 2011-05-18T04:02:56Z All about him he perceives in the midst of the worst wrongs and evils many fertile germs of righteousness; vice itself seems to distil its own antitoxin. Prophets of Dissent : Essays on Maeterlinck, Strindberg, Nietzsche and Tolstoy 2011-05-17T02:00:20.900Z The bacillus remains after the use of antitoxin just as if antitoxin had not been used. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z As an interne at a hospital during an epidemic of diphtheria he took a dose of diphtheria antitoxin for immunizing purposes. Psychotherapy 2011-06-19T02:00:20.053Z We owe the invention of diphtheria antitoxin entirely to experiments on animals. The Pros and Cons of Vivisection 2011-08-23T02:00:31.033Z The use of antitoxin, which prevents annually many thousands of deaths from diphtheria, does not help us in many other diseases. Proceedings of the Second National Conservation Congress at Saint Paul, September 5-8, 1910 2011-05-07T02:00:26.100Z The antitoxin, although making some people uncomfortable for a day or two, never does any real harm. Diphtheria how to recognize the disease, how to keep from catching it, how to treat those who do catch it 2011-05-03T02:00:14.537Z The acquired antitoxin lasts after smallpox, vaccinia, yellow fever, scarlet fever, measles, typhoid, mumps, and whooping-cough; it is very transient after pneumonia, influenza, diphtheria, erysipelas, and cholera. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z Organs cannot perform their function, and are predisposed to disease from disuse and from weakness of the disease-fighting phagocytes and antitoxins. Degeneracy Its Causes, Signs and Results 2011-05-02T02:00:17.657Z This blood is then rich in antitoxin, the natural antidote that has enabled the horse to get well again. The Pros and Cons of Vivisection 2011-08-23T02:00:31.033Z Today we give antitoxin and the child's life is saved. Little Pills, An Army Story Being Some Experiences of a United States Army Medical Officer on the Frontier Nearly a Half Century Ago 2011-04-28T02:00:13.453Z Diphtheria is preventable and, when properly treated with antitoxin, is curable. Diphtheria how to recognize the disease, how to keep from catching it, how to treat those who do catch it 2011-05-03T02:00:14.537Z The membrane often will disappear in twenty-four hours where antitoxin has been used, and the child will be playing about the floor. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z To the direct toxic effects of alcohol are therefore added results of imperfect liver and kidney action and defective strengthening powers from deficient antitoxin secretion. Degeneracy Its Causes, Signs and Results 2011-05-02T02:00:17.657Z With its antitoxins damaged, the toxins present within the bacterial cell are left unchecked and damage the cell’s metabolic processes so that it essentially shuts down, he adds. How Some Bacteria Hide From Antibiotics 2011-04-27T15:33:00Z In the early days of the employment of diphtheria antitoxin, all of these complications were noted in many cases. Makers of Modern Medicine 2011-03-05T03:00:29.580Z The night we discovered the Hamilton antitoxin, the night that made the Baker Institute famous! Why Marry? 2011-02-26T03:00:44.307Z Nearly the same thing might be said of antitoxin for diphtheria. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z An antibody for the hemolysin has been produced, but an antitoxin for the other poisonous substance seems to be formed in very small amount. Food Poisoning The probable explanation is that an antitoxin is developed within them. Encyclopaedia Britannica, 11th Edition, Volume 2, Slice 6 "Armour Plates" to "Arundel, Earls of" They were sufficient to make many who were interested in the demonstration of the value of antitoxin so disappointed and discouraged that they gave up the task. Makers of Modern Medicine 2011-03-05T03:00:29.580Z Why, Mr. Baker is tickled to death about the Hamilton antitoxin. Why Marry? 2011-02-26T03:00:44.307Z Clergymen seem to consider it necessary for them to have their minds made up as to whether the use of diphtheria antitoxin is advisable or not. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z The use of the antitoxin to the toxin of diphtheria is most efficacious in curing that disease, and the treatment has caused a great fall in the death-rate. The New Gresham Encyclopedia. Vol. 1 Part 2 Amiel to Atrauli The more recent furore against antitoxin is still in many persons' minds. The Popes and Science The History of the Papal Relations to Science During the Middle Ages and Down to Our Own Time The medical profession understands very well now how unfavorable were the conditions under which diphtheria antitoxin was used at first. Makers of Modern Medicine 2011-03-05T03:00:29.580Z An antitoxin exerts its effects by actual combination with the respective toxin, the combination being inert. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea" The only hope in such cases, is in Calmette's antitoxin, administered within an hour or two after the poisoning. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z Less success has been achieved when the disease is fully established, but if the antitoxin be injected immediately after the wound has been incurred, then the subsequent development of the disease is prevented. The New Gresham Encyclopedia. Vol. 1 Part 2 Amiel to Atrauli Weichardt has also obtained, by the usual methods," he replied, "an antitoxin with the power of neutralizing the fatigue properties of the toxin. The Social Gangster It is almost providential that, notwithstanding this failure to understand the serum properly, the verdict of the profession did not go so generally against antitoxin as to condemn its use hopelessly. Makers of Modern Medicine 2011-03-05T03:00:29.580Z It is probable that the ultimate source of the antitoxin is to be found in the living cells of the tissues and that it passes from them into the blood. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea" If they have once committed themselves to the expression of the opinion that antitoxin is of no value, then no amount of evidence will succeed in changing their opinion. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z Finally, the counteracting effect of antitoxin in preventing the disintegrating action of the 294 diphtheritic toxin on the nervous tissues has been demonstrated pathologically. Encyclopaedia Britannica, 11th Edition, Volume 8, Slice 5 "Dinard" to "Dodsworth" That person," pursued Kennedy relentlessly, "was defeated in the attempt to discredit Murchie when, by my injection of the antitoxin, Lady Lee finally did win. The Social Gangster There was another difficulty, however, in the way of the adoption of antitoxin that had to be overcome, one that proved no little source of discouragement to many of those who were testing the remedy. Makers of Modern Medicine 2011-03-05T03:00:29.580Z Laboratory research goes on constantly, and doubtless many more substances will eventually be discovered that will reduce human misery as vaccines and antitoxin have already reduced it. American Red Cross Text-Book on Home Hygiene and Care of the Sick Reliable diphtheria antitoxin, used in proper quantity and early enough, is almost an absolute cure. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z This is partly accounted for by the use of antitoxin, which only began on a considerable scale in 1895, and did not become general until a year or two later at least. Encyclopaedia Britannica, 11th Edition, Volume 8, Slice 5 "Dinard" to "Dodsworth" In the testing and analyzing of serums and antitoxins and for experimental purposes generally the demand is enormous, thousands and thousands of them being used every year. The Raising and Care of Guinea Pigs A complete guide to the breeding, feeding, housing, exhibiting and marketing of cavies The original experiments had been made in the laboratory with small animals, and the amount of antitoxin necessary to produce good effects in human beings was not well understood. Makers of Modern Medicine 2011-03-05T03:00:29.580Z Serum.—The fluid which separates from the clot after blood has coagulated; especially, that containing an antitoxin. American Red Cross Text-Book on Home Hygiene and Care of the Sick In consequence, it was now being taken to Beaufort to receive the antitoxin—that new remedy for which such miracles were claimed. When the Cock Crows Since the antitoxin treatment was introduced in 1894 it has overshadowed all other methods. Encyclopaedia Britannica, 11th Edition, Volume 8, Slice 5 "Dinard" to "Dodsworth" Previous to October 25, 1907, there were as many units or standards for tetanus antitoxin as there were producers. Euthenics, the science of controllable environment a plea for better living conditions as a first step toward higher human efficiency After all, it must not be forgotten that the first doses of antitoxin contained at most 50 to 100 antitoxin units, as we now measure serum efficacy for the treatment of diphtheria. Makers of Modern Medicine 2011-03-05T03:00:29.580Z Death rates from diphtheria and typhoid fever have been greatly reduced by the use of antitoxin and antityphoid vaccine. American Red Cross Text-Book on Home Hygiene and Care of the Sick He insisted that in spite of what he had done, the baby should be taken to the town, in order to receive treatment with the antitoxin. When the Cock Crows Since then an enormous mass of facts has accumulated from all quarters of the globe, all testifying to the value of antitoxin in the treatment of diphtheria. Encyclopaedia Britannica, 11th Edition, Volume 8, Slice 5 "Dinard" to "Dodsworth" As for diphtheria antitoxin, it is in the same class as the white of an egg. Carmen Ariza It is owing to O'Dwyer and a few other sympathetic souls, who "hoped almost against hope," that finally experience succeeded in demonstrating the true value of diphtheria antitoxin. Makers of Modern Medicine 2011-03-05T03:00:29.580Z A special antitoxin for use in treating snake bite is now prepared and may be had from the leading druggists. Special Report on Diseases of Cattle A religious epidemic is not analogous to those physical disorders which deposit an antitoxin and so protect against future attacks. Religion & Sex Studies in the Pathology of Religious Development On Acor we have abolished disease entirely, having a reagent or an antitoxin for every malady; we will use our cures upon you immediately after we have seen how you react to each disease. Astounding Stories of Super-Science, November, 1930 They are foredoomed to failure, despite the discovery of antitoxins. Carmen Ariza Not so, however, with O'Dwyer, who continued its use, and encouraged others by his example so that in spite of these objections antitoxin obtained a firm foothold. Makers of Modern Medicine 2011-03-05T03:00:29.580Z Some vaccines and antitoxins are administered in this way. Special Report on Diseases of Cattle Modern thought turns to test-tube and microscope, searches for the malignant germ, and manufactures an antitoxin. Religion & Sex Studies in the Pathology of Religious Development To make use of the antitoxin at the proper stage of the disease, early recognition is important, and fortunately science here can be of great service. Rural Hygiene This route is sometimes selected for the induction of spinal anæsthesia, and for the injection of antitoxin in cases of tetanus. Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. The antitoxin made him dizzy and he lost some blood before he could get the wound dressed. Deathworld We had popular education, aseptic surgery, the wireless, and antitoxin, but war came nevertheless, and in the wake of Hague conferences and much preaching of internationalism. The Story of the Great War, Volume I (of 8) Introductions; Special Articles; Causes of War; Diplomatic and State Papers The antitoxin has been found, and it is applied successfully. The Battle with the Slum The fourth disease for which an antidote in the form of antitoxin has been developed is tetanus, commonly known as lockjaw. Rural Hygiene It does not contain the antitoxins and opsonins which are normally found in the plasma and lymph, hence the liability to infective meningitis after injuries and operations on the central nervous system. Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. The machine clicked and Meta jumped as the antitoxin needle stabbed down. Deathworld The proper dose and method of employing antitoxin it is impossible to impart in a book of this kind. The Home Medical Library, Volume II (of VI) By the issuance alone of vaccine and antitoxin, the Board saved to the citizens of the State $210,000, or $74,000 more than the total appropriation for all the varied work of the institution. McClure's Magazine, Vol. XXXI, No. 3, July 1908. The more reasonable treatment is to inject the antitoxin, which neutralizes the poison and prevents, or at least minimizes, the disease. Rural Hygiene It has, moreover, been found that the serum of various animals has a certain amount of antitoxic action, and thus the basis for antitoxin production, according to Ehrlich's theory, is afforded. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" There are no remissions in the various antitoxins; there is no hope for you through hollow needles. The No Breakfast Plan and the Fasting-Cure That is one sort of "immunity" or "resistance" which we can confer, and is largely in use at the present day—the "antitoxin" treatment. More Science From an Easy Chair The old death rate from diphtheria, before antitoxin was discovered, ranged from 35 to 50 per cent. of those stricken. McClure's Magazine, Vol. XXXI, No. 3, July 1908. Rabies is the third assumed bacterial disease which is reacted upon by the administration of an antitoxin. Rural Hygiene The theory also supplies the explanation of the power which an animal possesses of producing various antitoxins, since this depends ultimately upon susceptibility to toxic action. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" Since then the medical world has advanced to antitoxin as a specific, leaving me nearly alone to plodding ways that are by sight and not by faith. The No Breakfast Plan and the Fasting-Cure The first is the power to convert the poison of a microbe into a destroyer of that poison—toxin into antitoxin. More Science From an Easy Chair Treatment.—Diphtheria antitoxin is the specific treatment of this malady, and should be given early in the disease. Health on the Farm A Manual of Rural Sanitation and Hygiene The health officer visited the house, offered to use antitoxin, which was refused, and instructed quarantine. Rural Hygiene In recent years the relations of toxin and antitoxin, still obscure, have been the subject of much study and controversy. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" The theory is advanced that the stock develops antitoxins to these foreign bodies which succeed in killing the scion a few weeks later. Northern Nut Growers Association Report of the Proceedings at the Thirty-Seventh Annual Report Wooster, Ohio, September 3, 4, 5, 1946 The healthy blood converts any one of a large series of microbe poisons into antitoxins. More Science From an Easy Chair It is well to remember that it is safer to give too much antitoxin than too little. Health on the Farm A Manual of Rural Sanitation and Hygiene This special prevalence of the disease is so well recognized that health officers usually lay in a large stock of antitoxin about the first of July, awaiting the inevitable demand for it. Rural Hygiene In view of the fact that antitoxin has a direct action on toxin, we may say that theoretically this may take place in one of two ways. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" The trained, clean mind develops a moral antitoxin which at every pulse-beat of life destroys the poisonous toxins produced by the germs which enter the system. Psychology and Social Sanity Gunpowder was invented long before the antitoxin for diphtheria was discovered. Gossamer 1915 There are very few risks in giving antitoxin. Health on the Farm A Manual of Rural Sanitation and Hygiene The most important result of bacterial studies has been the production of what are known as antitoxins, and no more wonderful discovery has ever been made. Rural Hygiene One other important fact in support of what has been stated is that a toxin may have its toxic action diminished, and may still require the same amount of antitoxin as previously for neutralization. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" The spirit of the man was invincible, and then, too, his knowledge of the drugs, both Adresol and those antitoxins which he had been forced to oppose to it, was well-nigh complete. The Heart of Unaga Prevention.—When a valuable horse has sustained a wound that it is feared may be followed by tetanus, it is well to administer a dose of tetanus antitoxin. Special Report on Diseases of the Horse This hypersensitiveness is manifested by the extraordinary peculiarity that any number of doses of antitoxin may be given provided they are administered within a period of less than ten or twelve days. Health on the Farm A Manual of Rural Sanitation and Hygiene The writer feels that it is in these last two methods of prevention rather than in the use of antitoxin that the hope of the future lies. Rural Hygiene There is, however, still dispute with regard to the exact nature of the union of toxin and antitoxin. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" An American invented the German submarine; an American invented the German torpedo; an American invented the German machine-gun; an American invented the Murphy button, the yellow fever antitoxin, the Dakin solution. The Blot on the Kaiser's 'Scutcheon Tetanus antitoxin appears to be useful as a remedy in some cases, if given in very large quantities early in the disease; otherwise it is useless. Special Report on Diseases of the Horse Should he now contract diphtheria, we would be confronted with the possibility that the treatment by means of antitoxin might possibly produce serious and even fatal results. Health on the Farm A Manual of Rural Sanitation and Hygiene At present, rabies, tetanus, diphtheria, and cerebrospinal meningitis are the four diseases for which antitoxin is made commercially and generally used. Rural Hygiene As, however, most of the work has been done with regard to antitoxin production we may consider here the theoretical aspect of the subject. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" They are going to try that new treatment—antitoxin. A Modern Tomboy A Story for Girls Meanwhile the bacteriologists are steadily at work on a vaccine or antitoxin. Preventable Diseases In addition to the antitoxin all that can be done is to keep the patient quiet with anodynes, and to minister to his comfort in every way possible. Health on the Farm A Manual of Rural Sanitation and Hygiene For that reason a physician should always be called because if it is "true" croup antitoxin must be given at once. 4th. The Eugenic Marriage, Volume IV. (of IV.) A Personal Guide to the New Science of Better Living and Better Babies The first of these, which would imply a process of a very remarkable nature, is disproved by what is observed after bleeding an animal whose blood contains antitoxin. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" One physician may challenge another's faults, ridicule his remedies, call his antitoxin dangerous poison, but their common profession he proudly styles "the most exalted form of altruism." Civics and Health Evidently some substance was produced in his blood which was a natural antidote for the toxin, and a little further search quickly resulted in discovering and filtering out of his body the now famous antitoxin. Preventable Diseases If we wait until the disease develops, the antitoxin is of no value. Health on the Farm A Manual of Rural Sanitation and Hygiene An examination of the throat contents,—a culture of which is taken during the first visit of the physician,—will, of course, reveal the true condition and dictate the future use of the antitoxin. The Eugenic Marriage, Volume IV. (of IV.) A Personal Guide to the New Science of Better Living and Better Babies In such a case it has been shown that, without the introduction of fresh toxin, new antitoxin appears, and therefore must be produced by the living tissues. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" Large cities should have their own pasteurizing plants, just as many cities now have their own vaccine farms and antitoxin laboratories. Civics and Health Could this antitoxin be obtained in sufficient amounts to protect the body of a human being? Preventable Diseases A physician is called at once, and, not only to the child, but to the other members of the family, antitoxin is immediately administered. The Mother and Her Child So important are these conditions that it is the proper treatment to give antitoxin at once in every case of tonsilitis that in the slightest way resembles diphtheria. The Eugenic Marriage, Volume IV. (of IV.) A Personal Guide to the New Science of Better Living and Better Babies In antitoxin production this combination takes place, though not in sufficient amount to produce serious toxic symptoms. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" When these dead, or half-dead, bacilli are injected into the system, they stir up the body to produce promptly large amounts of its antitoxin. A Handbook of Health These effects of the diphtheria toxin are also of interest for a somewhat unexpected reason, since it has been claimed that they are effects of the antitoxin, by those who are opposed to its use. Preventable Diseases The early use of antitoxin greatly lessens all these serious complications. The Mother and Her Child The difficulty here again is that if we wait till the diphtheritic membrane covers the whole throat, antitoxin will not be of much use. The Eugenic Marriage, Volume IV. (of IV.) A Personal Guide to the New Science of Better Living and Better Babies It has been found, for example, that a toxin may pass through such a filter while an antitoxin may not. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" Name the diseases for which we now have vaccines and antitoxins. A Handbook of Health We have no antitoxin and no bacteriologic means of positive diagnosis. Preventable Diseases These serious results are to be prevented by the science of good nursing and the prompt use of antitoxin. The Mother and Her Child Since the introduction of antitoxin we do not see the severe cases now, so that a description of them would not be of any use in a book of this character. The Eugenic Marriage, Volume IV. (of IV.) A Personal Guide to the New Science of Better Living and Better Babies The facts with regard to passive immunity were thus established and were put to practical application by the introduction of diphtheria antitoxin as a therapeutic agent in 1894. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" None of these vaccines is so powerful, or so certain in its effects, as the diphtheria antitoxin. A Handbook of Health Or if, as often happens, an antitoxin is formed, which protects the whole body, this is largely built out of substances set free from the bodies of slain leucocytes. Preventable Diseases The physician's prayer is the diphtheria antitoxin, which in his hands is the life-saving device. The Necessity of Atheism The deaths in most cases are children of the poorer classes who cannot afford to pay the exorbitant prices lately put upon antitoxin by the Medicine Trust. Born Again Theoretically there are two possible modes of action: antitoxin may act by means of the cells of the body, i.e. indirectly or physiologically; or it may act directly on the toxin, i.e. chemically or physically. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" Then came the idea that if they could only get enough of this antitoxin, and inject it into the blood of a child who had diphtheria, it might cure the disease. A Handbook of Health This was what we had to expect, in spite of our utmost effort, in from seventy to ninety per cent of these laryngeal cases, before the days of the blessed antitoxin. Preventable Diseases Laryngeal diphtheria is the condition most frequently thought of when these symptoms are present, and antitoxin is rightly given while waiting for a positive diagnosis. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery Chemistry, for instance, discovered an antitoxin for the deadly gangrene, or gas bacillus, poisoning of the battlefields. Kelly Miller's History of the World War for Human Rights If, however, toxin be mixed with antitoxin for some time, it can no longer be passed through, presumably because it has become combined with the antitoxin. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" We now have antitoxins, or vaccines, for blood-poisoning; for typhoid fever; for one of the forms of rheumatism; for boils; for the terrible cerebro-spinal meningitis, or "spotted fever"; and for tetanus, or lock-jaw. A Handbook of Health Not knowing the precise cause, we have as yet no reliable antitoxin for any. Preventable Diseases In doubtful cases, the administration of diphtheria antitoxin is a wise precaution pending the establishment of a definite diagnosis. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery The gangrene antitoxin is injected to prevent the development of gangrene poisoning. Kelly Miller's History of the World War for Human Rights Accordingly, the most actively toxic molecules will be neutralized first, and those which are left over, that is, uncombined with antitoxin, will have a weaker toxic action. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" In some cases the reaction is so prompt and so vigorous that the antitoxin is produced almost without any discomfort, or disturbance, and the patient scarcely knows anything about it. A Handbook of Health Workers in such fields or gardens, who scratch or cut themselves, are warned to report themselves promptly for treatment with the tetanus antitoxin. Preventable Diseases The local application of diphtheria antitoxin to the trachea and bronchi has also been recommended. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery The antitoxin method of treating diphtheria has robbed this disease of much of its terror, yet it not infrequently happens that the physician is called too late to administer this remedy to the best advantage. Physiology and Hygiene for Secondary Schools Arrhenius, who hold that the union of toxin and antitoxin is comparatively loose, and belongs to the class of reversible actions, being comparable in fact with the union of a weak acid and base. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" They are accompanied by fever, with headache, backache, and often chills; they "run their course" until the body has manufactured enough antitoxins to stop them, and then they get well of their own accord. A Handbook of Health If, in his experimental animals, he carefully sought for the cut end of the nerve-trunk in the wound that had been infected, and injected the antitoxin directly into that, the disease was stopped. Preventable Diseases When this antitoxin is injected into the blood, it will cure diphtheria. The Child's Day The Catholic paper, indeed, reacts as an antitoxin against the virus of unbelief and indifferentism which a non-Catholic atmosphere is bound to spread. Catholic Problems in Western Canada It may be stated that while in certain instances the union of toxin and antitoxin may be reversible, all the facts established cannot be explained on this simple hypothesis of reversible action. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" This can be done either by supplying it with antitoxin from an outside source, or helping it to make its own antitoxin by giving it dead germs to practise on. The Third Great Plague A Discussion of Syphilis for Everyday People Prophylactic injection of tetanus antitoxin may be indicated. Manual of Surgery Volume First: General Surgery. Sixth Edition. Everyday examples of their methods may be seen in the use of quinine in Malaria, antitoxins in Diphtheria and vaccines in Smallpox, etc. Mother's Remedies Over One Thousand Tried and Tested Remedies from Mothers of the United States and Canada The method may be considered as in accord with the modern theory that the bile of many animals contains strong antitoxins. Unknown Mexico, Volume 1 (of 2) A Record of Five Years' Exploration Among the Tribes of the Western Sierra Madre; In the Tierra Caliente of Tepic and Jalisco; and Among the Tarascos of Michoacan The development of the immune body with specific combining affinity thus presents an analogy to antitoxin production, the difference being that in lysogenesis another substance is necessary to complete the process. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" In diphtheria, nowadays, we help the body out promptly by supplying it with antitoxin from an outside source, before it has time to make any for itself. The Third Great Plague A Discussion of Syphilis for Everyday People The most important of these antibodies are the antitoxins. Manual of Surgery Volume First: General Surgery. Sixth Edition. The inefficiency of drugs is recognized and besides the articles of the Materia Medica the "regular" physician makes use of antitoxins, vaccines, surgery, electricity, baths, etc., in treating diseases. Mother's Remedies Over One Thousand Tried and Tested Remedies from Mothers of the United States and Canada If the infection is internal, antitoxins are produced within the body. Outwitting Our Nerves A Primer of Psychotherapy Ultimately the regeneration becomes an over-regeneration and free side-chains produced in excess are set free and appear in the blood as antitoxin molecules. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" It is as safe to take salvarsan at the hands of an expert as it is to take ether for an operation or to take antitoxin for diphtheria, and that is saying a good deal. The Third Great Plague A Discussion of Syphilis for Everyday People Leucocytosis is usually well marked before the injection of antitoxin; after the injection there is usually a diminution in the number of leucocytes. Manual of Surgery Volume First: General Surgery. Sixth Edition. Some homeopathic doctors claim that the antitoxin treatment for diphtheria, etc. is an application of the homeopathic law. Mother's Remedies Over One Thousand Tried and Tested Remedies from Mothers of the United States and Canada I sat down and wrote to Melrose peremptorily demanding a proper supply of antitoxin at once, at his expense. The Mating of Lydia In other words the substances, which when forming part of the cells fix the toxin to the cells, constitute antitoxin molecules when free in the serum. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" Perhaps antitoxin; I don't know; perhaps formalin later. The Tracer of Lost Persons The fatigue toxin in normal quantities is said to be counteracted by an antidote or antitoxin, also generated in the body. What eight million women want After the first treatment with antitoxin she seemed to rally, her throat cleared up, but I soon found that the poison had pervaded her entire system, and so I stayed with her day and night. Court Life in China That night, however, on arriving at my surgery, I found a splendid supply of antitoxin, labelled 'for Mainstairs,' without another word. The Mating of Lydia Further, these molecules in the nervous system present the same susceptibility to heat and other physical agencies as does tetanus antitoxin. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" Indigency, like typhus, was a pandemic which must ultimately respond to an antitoxin. Star-Dust "Fads may be said to constitute a perfect mental antitoxin for the poison generated by cerebral acuity." Why Worry? In communities, or on premises where tetanus is a common disease, animals that have punctured or open wounds should be given a protective dose of tetanus antitoxin. Common Diseases of Farm Animals She, the missionary nurse, thereupon took up her station in the sick room, kept out the numerous callers, administered antitoxin, and nursed the child back to life. Home Missions in Action There is therefore strong evidence that antitoxin molecules do exist as part of the living substance of nerve cells. Encyclopaedia Britannica, 11th Edition, Volume 3, Part 1, Slice 2 "Baconthorpe" to "Bankruptcy" In those early days, before the antitoxin treatment of the disease, diphtheria in Southern California was the deadliest of plagues. Bunch Grass A Chronicle of Life on a Cattle Ranch Lucky for us that we did not need to inject the wounded with tetanus antitoxin. Sketches of the East Africa Campaign Tetanus antitoxin may be given in large doses. Common Diseases of Farm Animals She gave the antitoxin treatment in other cases where the parents were willing. Home Missions in Action A sample of the blood from this person will be identical with the spot on the portiere, and—much the easier test—will contain traces of the antitoxin. The Film Mystery If an animal that is immune to a toxin is bled and the serum collected, the antitoxin in it may be injected into a healthy animal and render it immune. The Treasure-Train Yet people expect to find vaccines and antitoxins and the like retailed at "popular prices" in private enterprise shops just as they expect to find ounces of tobacco and papers of pins. The Doctor's Dilemma: Preface on Doctors In order to hold in check the destructive activity of bacteria and to prevent their multiplication beyond the danger point, Nature resorts to inflammation and manufactures her own antitoxins. Nature Cure And in three minutes he had given all four an antitoxin injection. The Doctor : a Tale of the Rockies Ten minutes later he was on his way to the station with the little wooden case containing the precious antitoxin, wrapped and addressed, in his pocket. The Depot Master I am that desperate that I would try the Noguchi antivenene, but it would have no more effect than the antitoxin. The Treasure-Train But we of the Nature Cure school claim and can prove that the hydropathic treatment of diphtheria shows a much lower percentage of mortality than the antitoxin treatment. Nature Cure All feverish diseases are more or less interfered with or suppressed by antiseptics, antipyretics, serums and antitoxins. Nature Cure I make the following claims: that the antitoxin, being itself a most powerful poison, may be and often is the direct cause of paralysis, or of death due to heart-failure. Nature Cure It directs him to send the antitoxin by the early train. The Depot Master That diphtheria treated with antitoxin may be and often is followed by paralysis, heart-failure, or lifelong invalidism of some kind after the patient has apparently recovered from the disease. Nature Cure That these undesirable after-effects of diphtheria do not occur when the disease is treated by natural methods, but that they are the result of the antitoxin treatment and of its suppressive effect upon. the disease. Nature Cure It has also been found that the phagocyte and tissue cells in the neighborhood of the area of irritation produce antipoisons or natural antitoxins, which neutralize the bacterial poisons and kill the microorganisms of disease. Nature Cure It was thought to be a case of diphtheria, and the doctor, to protect his little son, one and one-half years old, against possible infection, administered an injection of antitoxin. Nature Cure If I could administer antitoxin by to-morrow noon the patient might recover. The Depot Master In his announcement in the columns of the "Lokalanzeiger," Dr. Langerhans stated explicitly that his little son had died after an injection of diphtheria antitoxin for immunization. Nature Cure The child was given an injection of antitoxin, and this was followed by a severe and protracted illness. Nature Cure The vaccines, serums and antitoxins of medical science are prepared from these bacterial excrements and from extracts made of the bodies of bacteria. Nature Cure The cases that Dr. Osler refers to undoubtedly received the antitoxin treatment, because it is administered on the slightest suspicion of diphtheria, nay, even to perfectly healthy persons "for purposes of immunization." Nature Cure That gentleman had telegraphed for antitoxin, and said it was important that he should have it; therefore, antitoxin must be sent in spite of time-tables and forgetful butlers. The Depot Master Then is it not most likely that these "mysterious after-effects" are caused rather by the highly poisonous antitoxin than by the "sore throat?" Nature Cure In my own practice, I am frequently consulted by chronic patients whose troubles date back to diphtheria "cured" by antitoxin. Nature Cure Therefore, we claim that there is no necessity for the employment of poisonous drugs, serums and antitoxins for this purpose. Nature Cure In the iris of the eye, the effect of the antitoxin on the system shows as a darkening of the color. Nature Cure She does not remember whether she was given antitoxin, but recalls that her throat was painted and her body rubbed with oil, and that she had to take a great deal of medicine. Nature Cure The effect upon the iris of the eye would be very much the same whether the attacks of diphtheria had been suppressed by antitoxin or by the old-time drug treatment. Nature Cure You replied: "You know what to do—wet packs, no food except fruit juices, osteopathic treatment and no antitoxin." Nature Cure According to the enthusiastic advocates of this treatment among the "regular" physicians in this country, the antitoxin is a "certain cure" for diphtheria; but how is this claim borne out by actual facts? Nature Cure A physician from the Board of Health came and quarantined us and inquired if we had used the antitoxin treatment. Nature Cure In contrast to this experience of ours, I would like to cite the case of a neighbor of ours whose little girl died of the disease under the antitoxin treatment. Nature Cure The experience of Mr. White's neighbor is another proof of the fatal effect of the antitoxin treatment. Nature Cure Vaccination The pernicious aftereffects of vaccination upon the system are similar to those of the various serum and antitoxin treatments. Nature Cure The Health Bulletins sent regularly to every physician in the City of Chicago by the City Health Department show an average of from fifteen to twenty deaths every week from diphtheria treated with antitoxin. Nature Cure Modern allopathy, in applying the isopathic principle, gives large and poisonous doses of virus, lymph, serums and antitoxins, while homeopathy, as did ancient mysticism, applies the isopathic remedies in highly diluted and triturated doses only. Nature Cure Looking Forward At present the trend of allopathic medical science is undoubtedly toward the serum, antitoxin and vaccine treatment. Nature Cure Every few days we see in the daily papers reports of new serums and antitoxins which are claimed to cure or create immunity to certain diseases. Nature Cure Therefore neurotherapy would not suppress acute processes by manipulative treatment any more than by drugs, ice, antitoxins, surgery or any other suppressive method. Nature Cure I do not deny that the antitoxin treatment may have reduced somewhat the mortality percentage of this disease, allowing even for the great uncertainty of medical statistics. Nature Cure |
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