| 单词 | heterozygosity |
| 例句 | LOH, loss of heterozygosity; NA, not available. c, Bar graph depicting the proportion of cases per subgroup for which at least one driver event could be assigned. The whole-genome landscape of medulloblastoma subtypes : Nature : Nature Research 2017-07-18T04:00:00Z Percentage heterozygosity within these genomes and the level of nucleotide variance between genomes are shown. The crown-of-thorns starfish genome as a guide for biocontrol of this coral reef pest : Nature : Nature Research 2017-04-04T04:00:00Z Homozygous mismatches are classified as sequencing errors, and heterozygous mismatches indicate sites of heterozygosity. Single-molecule sequencing of the desiccation-tolerant grass Oropetium thomaeum : Nature : Nature Publishing Group 2015-11-10T05:00:00Z A single male was used for each species to minimize the impact of heterozygosity on assembly. Hemichordate genomes and deuterostome origins : Nature : Nature Publishing Group 2015-11-17T05:00:00Z By comparison, East Asian populations exhibited the lowest levels of deletion heterozygosity and the highest levels of homozygosity. An integrated map of structural variation in 2,504 human genomes : Nature : Nature Publishing Group 2015-09-29T04:00:00Z LOH, loss of heterozygosity; NA, not available. c, Bar graph depicting the proportion of cases per subgroup for which at least one driver event could be assigned. The whole-genome landscape of medulloblastoma subtypes : Nature : Nature Research 2017-07-18T04:00:00Z Percentage heterozygosity within these genomes and the level of nucleotide variance between genomes are shown. The crown-of-thorns starfish genome as a guide for biocontrol of this coral reef pest : Nature : Nature Research 2017-04-04T04:00:00Z This limits the effects of local variation in heterozygosity rates throughout the genome on the likelihood of identifying allele-biased enhancers near allele-biased genes. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Ordinarily, greater genetic variation - or heterozygosity - is a good thing because it enables a population to better withstand disease and environmental stress. Fur seals feel climate impacts 2014-07-23T04:00:00Z By comparison, East Asian populations exhibited the lowest levels of deletion heterozygosity and the highest levels of homozygosity. An integrated map of structural variation in 2,504 human genomes : Nature : Nature Publishing Group 2015-09-29T04:00:00Z One would expect 50% under the null model, but almost the entire chromosome is biased towards heterozygosity. The genome of Eucalyptus grandis : Nature : Nature Publishing Group 2014-06-10T04:00:00Z Such methods may not yet be applicable to every rare disease scenario, and will require work to extend to more exotic inheritance modes such as parental imprinting or obligate compound heterozygosity. Guidelines for investigating causality of sequence variants in human disease 2014-04-23T17:21:03.147Z Table 1: Genetic variation summary by species and subspecies Figure 1: Samples, heterozygosity and genetic diversity. a, Geographical distribution of great ape populations across Indonesia and Africa sequenced in this study. Great ape genetic diversity and population history 2013-07-24T17:21:11.837Z Figure 2: Distribution of heterozygosity for individual pig genomes. Analyses of pig genomes provide insight into porcine demography and evolution 2012-11-14T18:22:24.580Z The wild rice accessions with sequencing coverage >9 were selected to investigate the heterozygosity based on the overlapped reads that were aligned onto the reference sequence. A map of rice genome variation reveals the origin of cultivated rice 2012-10-24T17:21:24.910Z One would expect 50% under the null model, but almost the entire chromosome is biased towards heterozygosity. The genome of Eucalyptus grandis : Nature : Nature Publishing Group 2014-06-10T04:00:00Z Furthermore, heterozygosity in Mukisi is much lower, suggesting a reduced population size in the eastern species. Insights into hominid evolution from the gorilla genome sequence 2012-03-07T18:21:00.777Z Therefore, populations of pygmy mice occurring to the south in central M�xico might be expected to maintain a relatively high degree of heterozygosity in morphological and behavioral characters. Speciation and Evolution of the Pygmy Mice, Genus Baiomys 2011-12-15T03:00:11.933Z Figure 2: Distribution of heterozygosity for individual pig genomes. Analyses of pig genomes provide insight into porcine demography and evolution 2012-11-14T18:22:24.580Z In contrast to the single modality of DM, RH exhibits clear bi-modality caused by heterozygosity. c, Genomic distribution of premature stop, frameshift and presence/absence variation mutations contributing to inbreeding depression. Genome sequence and analysis of the tuber crop potato 2011-07-13T17:21:42.673Z Despite the strong bias towards heterozygosity in these regions, a small proportion of either homozygous haplotype was always present, suggesting that there are genetic backgrounds in which homozygosity of any particular gene is not lethal. The genome of Eucalyptus grandis : Nature : Nature Publishing Group 2014-06-10T04:00:00Z The scientists also sequenced substantial sections of the heterozygous diploid variety RH, although due to its heterozygosity were not able to assemble it into a complete genome. Scientists Finally Sequence Tricky Potato Genome 2011-07-10T21:15:00.257Z First, three of the four tumours with mutations exhibited loss of heterozygosity via deletion of the remaining allele. Initial genome sequencing and analysis of multiple myeloma 2011-03-23T18:52:33.100Z Had mountain goats simply spread back from this region, one would expect a northward decrease in genetic heterozygosity and a nested phylogeny. Editors' Choice 2011-02-03T19:25:02.600Z High heterozygosity and inbreeding depression are inherent to potato, a species that predominantly outcrosses and propagates by means of vegetative organs. Genome sequence and analysis of the tuber crop potato 2011-07-13T17:21:42.673Z In contrast to the single modality of DM, RH exhibits clear bi-modality caused by heterozygosity. c, Genomic distribution of premature stop, frameshift and presence/absence variation mutations contributing to inbreeding depression. Genome sequence and analysis of the tuber crop potato 2011-07-13T17:21:42.673Z |
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