| 单词 | heterogeneity |
| 例句 | Mr. Maillot’s preference for heterogeneity means that the school is not a feeder for the 48-strong company. Jean-Christophe Maillot Brings ‘Lac’ to City Center 2014-03-13T22:17:53Z In some previous years, the available pool of work has been weaker or thinner, and the committee has at times pursued a narrow aesthetic agenda at odds with the essential heterogeneity of the art form. Critic?s Notebook: A Film Festival With a Penchant for Making Tastes, Not Deals 2010-09-23T22:17:00Z However you define it, for Amos, there was resistance and freedom in heterogeneity — an ability to be her multiple selves at once and an opportunity to rethink the tropes and traps of history. The Many Styles of Emma Amos, and Her Drive to Get Free 2021-10-21T04:00:00Z The sheer heterogeneity could be called a kind of sales strategy — something for everyone — and also an earnest commitment to democratization. Worth the Ride: 5 Surprising Exhibition Spaces in Upstate New York 2018-08-30T04:00:00Z Since I really wanted to explore heterogeneity, I couldn't just look like a guy up on the stage, and I can't look like a guy who's trying to look like a woman on stage. For Taylor Mac, the stage show is just part of the fight for the LGBT community 2016-03-11T05:00:00Z “There is no monolithic American fashion,” said Mr. Bolton, who for “In America: A Lexicon of Fashion’’ radically expanded the curatorial brief to encompass “American fashion in all its heterogeneity.” ‘Stick It to the Man’ and Other Lessons From the Met Gala Cocktails 2021-09-14T04:00:00Z Organized by Facebook Open Arts in partnership with We the Culture and ArtBridge, Not a Monolith was established to show the heterogeneity of Black art. 5 Things to Do This Weekend 2021-06-24T04:00:00Z The asymmetrical arrangement of the discs — whose razor-thin edges emphasize the building’s lightness — speaks to contemporary architectural ideas about heterogeneity and openness. Architecture Review: Celebrating the Delicate Beauty of the Desert Landscape 2010-03-22T22:46:00Z And at the very least, its tableau of heterogeneity keeps things interesting. American Gods recap: season one, episode three – the man with fire in his eyes 2017-05-14T04:00:00Z Brain injuries are noteworthy for their heterogeneity; an affected person can perform certain tasks--light social interactions, for instance--yet suddenly have a flare of impulsive, reactive behavior that can cause great harm. Tracy Morgan Is a Survivor. And ‘a Better Man Now.’ 2018-03-14T04:00:00Z The sheer heterogeneity of human experience is one of his enduring preoccupations, and he has found, once again, an impossible and perfect embodiment of just how curious our species can be. | 'Tabloid': Was It Love? The ?Manacled Mormon? and His Kinky Weekend 2011-07-14T22:11:29Z But it’s also hard to ignore the irony here: Universities are now terrible places to find political heterogeneity. ‘Unwanted Advances’ Tackles Sexual Politics in Academia 2017-04-05T04:00:00Z Research papers estimate the prevalence is anywhere from 0.5 to 6 percent thanks to the wide variation in how it’s defined and the heterogeneity in study designs. Perspective | Want a verdict on gluten-free diets? You won’t find it in a study. 2017-06-01T04:00:00Z Thus one wonders why the history of the elevator should rest on a single, canonical incident despite the multifarious data, a heterogeneity that only increased in the decades preceding Otis’s experiment. The most important invention in the history of the modern city 2014-02-23T13:00:00Z They’re quickly turned into plot points that push ahead to another scene, another action; their narrative connections remain too obvious and strip them precisely of their heterogeneity. Mike Mills’s Too-Sweet “20th Century Women” 2017-01-11T05:00:00Z And so focusing on 12 black British women was my way of addressing our invisibility and also exploring our heterogeneity. Booker Prize Winner ‘Girl, Woman, Other’ Is Coming to America 2019-11-01T04:00:00Z “We expect a level of heterogeneity among White people that communities of color aren’t granted,” she says. D.C.’s rising libertarian star, with her ‘healthy skepticism of state power,’ secures an influential podcast 2021-04-08T04:00:00Z The challenge when teaching is to structure knowledge without doing violence to its complexity and heterogeneity. Harvard’s three-in-one ‘teaching museum’ offers other art institutions much to learn 2014-12-31T05:00:00Z The series as a whole aims to avoid easy formulas and, instead, to exhibit the heterogeneity and individuality of modern-day witches, Denny told me recently, adding, “I’m not pinning these women down.” The Many Faces of Women Who Identify as Witches 2018-08-24T04:00:00Z Ms. Chavkin values what she calls “heterogeneity” in her troupes, and thought Mr. Hughes would fit into “the rust belt/heavy industry world in which our ensemble is rooted.” Solving the 6 Biggest Mysteries of This Broadway Season 2019-05-15T04:00:00Z And heterogeneity is all but on the menu at Burger Heaven, where both the customers and the staff mirror the city’s diversity of race, ethnicity and class. Everybody Goes to Burger Heaven 2020-02-25T05:00:00Z For example, I’m always amazed at the heterogeneity of flora and fauna I encounter camping in cities, which are popularly but erroneously considered biological dead zones. Above the streets, beneath the stars: why you should try urban rooftop camping 2016-06-18T04:00:00Z Sidestepping conflict and controversy, Ewald suggests that the best way to enter the conversation “This Place” sparks is by recognizing and understanding that heterogeneity. Israel and the West Bank, Through the Eyes of a Dozen Visitors 2016-03-16T04:00:00Z It’s this very heterogeneity, the readiness of filmmakers to open their stories and their films to the fullness of contingency, that lends even the most confected fiction an aspect of documentary. The Odd Factual Gaps in Michael Grandage’s “Genius” 2016-06-09T04:00:00Z Sequencing copolymers is so difficult in large part because of heterogeneity in synthetic polymers, Chen said. Chemists image basic blocks of synthetic polymers 2023-11-09T05:00:00Z This new insight emphasizes the importance of considering heterogeneities in public health research to understand who benefits from life satisfaction and who does not. Life satisfaction may not enhance cognitive functioning among some older adults 2023-09-29T04:00:00Z "I think that there's a real need to appreciate the heterogeneity of hardware that we are surrounded by all the time and look at it as a resource," Mandel said. 'Garbatrage' spins e-waste into prototyping gold 2023-09-20T04:00:00Z “The one tumor-one gene-one drug approach oversimplified cancer biology and did not take into account tumor heterogeneity, clonal evolution, or other mechanisms of resistance,” ComboMATCH’s leaders wrote in an April paper. U.S. study will test whether drug combinations can wipe out tumors 2023-06-01T04:00:00Z The complexity of tropical ecosystems may promote speciation by increasing the habitat heterogeneity, or number of ecological niches, in the tropics relative to higher latitudes. Concepts of Biology 2013-04-25T00:00:00Z If these pictures appear to have little in common beyond Dillon’s predilection for them, their heterogeneity is in part his point. Review | ‘Affinities’ opens our eyes to the ‘mundane miracle of looking’ 2023-04-20T04:00:00Z But the departing coalition’s heterogeneity was also its downfall. Coalition Deal Puts Netanyahu on Brink of Power in Israel 2022-12-21T05:00:00Z The "Zeitenwende" or epochal change of times, as Scholz dubbed it, has proven all the trickier given the heterogeneity of his government -- the first three-way coalition at national level in decades. Analysis: Germany's government looks inward as challenges mount, allies fret 2022-12-08T05:00:00Z Recognizing this heterogeneity, the Obama campaign aired campaign ads in 2012 that were tailored to particular Latino populations and their countries of origin. Echoes of Latin American Racism Reverberate in the U.S. 2022-10-14T04:00:00Z Clumped dispersions may also be a function of habitat heterogeneity. Biology for AP Courses 2022-06-09T00:00:00Z But its heterogeneity and slender majority made it increasingly prone to crisis, with lawmakers from its left and right constantly threatening to resign if their personal demands were not met. Israel’s Government Teeters Again, Losing Vote on Law that Supports West Bank Settlers 2022-06-06T04:00:00Z This heterogeneity does come at a price, though. Perspective | The European Union needs its own army 2022-05-18T04:00:00Z Such heterogeneity in cities subconsciously plants seeds of appreciation for diversity, tolerance and empathy that can benefit the natural world. Cities Build Better Biologists 2022-04-22T04:00:00Z And Diaz and Rousseau argue that their team’s two-drug approach will spin out so many potent neoantigen targets for T cells that any harm from greater genetic heterogeneity within the tumor will be minimal. Surprising strategy would fight mutant cancer cells by making more mutations 2022-04-19T04:00:00Z The complexity of tropical ecosystems may promote speciation by increasing the heterogeneity, or number of ecological niches, in the tropics relative to higher latitudes. Biology for AP Courses 2022-06-09T00:00:00Z In the past year, however, the number of cases has exploded to more than 1,000 with a heterogeneity of symptoms. Opinion | The ‘Havana syndrome’ is still a mystery. It is too soon to stop investigating. 2022-01-23T05:00:00Z Despite this heterogeneity, PRS studies have generally demonstrated the ability to boost the sensitivity of risk assessment for coronary heart disease. Ranking the Risk of Heart Disease 2021-11-30T05:00:00Z And considering the heterogeneity of autism, it’s possible that a subset of autistic people will still respond to an oxytocin-based treatment, Anagnostou says. Large Trial Finds Oxytocin Nasal Spray Is Ineffective for Autism 2021-10-14T04:00:00Z We’re told there is a great deal of heterogeneity in the cases. Opinion | The source of the ‘Havana syndrome’ must be found. National security demands it. 2021-09-28T04:00:00Z The greater heterogeneity provides more opportunities for coevolution, specialization, and perhaps greater selection pressures leading to population differentiation. Biology for AP Courses 2022-06-09T00:00:00Z There's so much heterogeneity across kids and across families, both in what questions they have and in how to think about the answers to those. Emily Oster’s parenting wisdom is wildly popular with some and lambasted by others. Here's why 2021-08-03T04:00:00Z "They were moving and creating a landscape that had great heterogeneity," he added. When the bison come back, will the ecosystem follow? 2021-06-02T04:00:00Z Let’s teach our children about the considerable heterogeneity within Asian cultures, and at the same time, the importance of a pan-Asian identity for Asian American communities. Yes, Asians and Asian Americans experience racism 2021-03-10T05:00:00Z At the very least, the term disorder suggests a common causal structure, which goes against all our current knowledge on causal heterogeneity in psychiatry. We Need to Rename ADHD 2021-03-08T05:00:00Z “That will help in focusing the response, so you don’t get the same kind of heterogeneity that you would see in an infected population,” she said. Immunity to the coronavirus may last years, new research suggests 2020-11-17T05:00:00Z Not much heterogeneity between Germany, France and Italy as regards the Q3 GDP level. Eurozone emerges from Covid-19 slump with fastest growth on record – business live 2020-10-30T04:00:00Z In the company statement sent to Fox News, Gilead pointed to the WHO trial's "significant heterogeneity in trial adoption, implementation, controls and patient populations" because the trial design prioritized broad access. 4 coronavirus treatments, including remdesivir, hydroxychloroquine, flop in large WHO study 2020-10-16T04:00:00Z Because of its design, there was “significant heterogeneity” in the way the trial was conducted. Remdesivir fails to prevent COVID-19 deaths in large trial 2020-10-15T04:00:00Z Whether tissue-agnostic or not, Horning adds, approvals of these types of drug and their combinations are all about understanding the heterogeneity of the disease. The future of tissue-agnostic drugs 2020-09-22T04:00:00Z To cope with that challenge, researchers have in recent years begun to posit the concept of "heterogeneity." Why "herd immunity" is a distraction 2020-09-11T04:00:00Z In a paper published in Science in June, he and other researchers estimated that population heterogeneity shaves the coronavirus herd immunity rate to 43 percent. In the Brazilian Amazon, a sharp drop in coronavirus sparks questions over collective immunity 2020-08-23T04:00:00Z What is making it difficult to contain the infection is the country's size, population and heterogeneity. India surpasses two million Covid-19 cases 2020-08-06T04:00:00Z We must also continuously question why we distill the complex heterogeneity and diversity of our backgrounds into inflexible racial categories. Medical Students Should Be Taught How to Care for Immigrant Patients 2020-07-13T04:00:00Z This bloom of life lasted for months and spread through food chains – even creating scrubby areas and heterogeneity in the landscape, scientists found. 'Landscape of fear': what a mass of rotting reindeer carcasses taught scientists 2020-07-08T04:00:00Z Efforts to clarify these therapeutic mechanisms are further confounded by the considerable heterogeneity in exosome preparations. Inside the stem-cell pharmaceutical factory 2020-06-16T04:00:00Z The blanket application of R in the context of such population heterogeneities seems questionable. Coronavirus R number hides raised risk for minority ethnic groups 2020-06-09T04:00:00Z Given the heterogeneity of groups we call “black” or “white,” treating those categories as proxies for genetic variation almost always leads us astray. Racism, Not Genetics, Explains Why Black Americans Are Dying Of COVID-19 2020-06-07T04:00:00Z Previously calculated cluster-growth rates in cities were averaged over space and time, and therefore did not capture this heterogeneity. Airborne particles might grow fast in cities 2020-05-12T04:00:00Z In Hardangervidda – the largest plateau in Europe – carcasses are likely to be benefitting biodiversity and creating heterogeneity in ecosystems. 'Landscape of fear': what a mass of rotting reindeer carcasses taught scientists 2020-07-08T04:00:00Z One of the things I’m particularly interested is the heterogeneity in welfare among different ages and different types of worker. This physicist-turned-economist is modelling the pandemic’s financial fallout 2020-05-03T04:00:00Z By contrast, the AID equates inequality with heterogeneity in educational attainment within a population. Tracking inequalities in education around the globe 2020-04-14T04:00:00Z The top doctor also acknowledged that multiple factors were involved with the current situation in the US, such as the nation's size and heterogeneity, not just a later start on mitigation. US 'could have saved lives' with earlier action 2020-04-12T04:00:00Z I argue it is important to see the heterogeneity of black Americans. Black Americans are not a monolithic group so stop treating us like one | Rashawn Ray 2020-02-14T05:00:00Z This fourth wave of the far right exists in extreme heterogeneity, but they do share some common ideas. Impeachment won't slow the global rise of the radical right — but an alternative vision might 2019-12-19T05:00:00Z These inefficiencies are not only due to imperfect demand forecasts, but also to heterogeneity within individual rush hours. How Bike Sharing Can Be More Efficient 2019-10-30T04:00:00Z This distinctive population of Type II diamonds reveals a previously undocumented heterogeneity in the mantle. Why Carbon? 2019-10-22T04:00:00Z The immune system really thrives on diversity and heterogeneity. "Breakthrough's" James Allison is having fun and curing cancer 2019-09-27T04:00:00Z The fourth wave is characterized by extreme heterogeneity as well as mainstreaming and normalization, all of which were on display in Houston this weekend. Trump and Modi are the mainstream faces of the global far-right | Cas Mudde 2019-09-23T04:00:00Z Strong reactions to touch are remarkably widespread among people who have autism, despite the condition’s famed heterogeneity. ‘I will feel actual rage.’ Unusual responses to kind touches could help explain autism traits 2019-05-29T04:00:00Z So what is the huge heterogeneity in the autism spectrum? The Concept of Neurodiversity Is Dividing the Autism Community 2019-04-30T04:00:00Z Both figures embody a heterogeneity that Hugo saw as a reflection of nature’s fundamental versatility. Victor Hugo gave Notre Dame life as the vibrant heart of France. It can be reborn | Bradley Stephens 2019-04-22T04:00:00Z The GOP is the party of older people; the Democrats are the party of the young, partly because of the racial and ethnic heterogeneity of the rising generations. Opinion | Democrats need to pick up this trait. Republicans need to nix it. 2019-04-14T04:00:00Z That heterogeneity extends to the few studies done on antibiotic resistance. Antibiotics set to flood Florida’s troubled orange orchards 2019-03-18T04:00:00Z Shugerman does, however, raise an important point about the normative heterogeneity that exists within the world of constitutional hardball. Welcome to the era of constitutional beanball: How Republican dirty tricks got even dirtier 2019-02-09T05:00:00Z The other source of the huge heterogeneity is that autism is frequently accompanied by co-occurring conditions. The Concept of Neurodiversity Is Dividing the Autism Community 2019-04-30T04:00:00Z "We were aiming to get heterogeneity, but it's difficult." Huge trove of British biodata is unlocking secrets of depression, sexual orientation, and more 2019-01-03T05:00:00Z Perhaps no specialty shows more heterogeneity with respect to the delivery of nonsurgical and surgical care than treatment of spinal disorders. How AI Could Help Your Bad Back 2018-12-19T05:00:00Z The paper notes the "heterogeneity" of the protesters - from nationalists and far-right student groups to hard-left militants and anarchists. Woman dies in France fuel protests 2018-12-03T05:00:00Z Her current work seeks insights into the heterogeneity within tumours. A venture under pressure 2018-10-30T04:00:00Z For a start, they show extreme genetic heterogeneity, which means that the mutations that contribute to their growth can differ dramatically across such tumours. Immunotherapy offers a promising bet against brain cancer 2018-09-25T04:00:00Z We were aiming to get heterogeneity, but it's difficult. Huge trove of British biodata is unlocking secrets of depression, sexual orientation, and more 2019-01-03T05:00:00Z Part of the problem may be that nobody really knows where to intervene for autism traits; and given the condition’s heterogeneity, the best location may well differ from one autistic person to the next. Can brain-stimulating implants treat some severe cases of autism? 2018-09-14T04:00:00Z The United States is not alone in confronting this puzzle, which Beckham calls “massive heterogeneity.” How a Government Program to Get Ethanol from Plants Failed 2018-07-16T04:00:00Z “For rapeseed, heterogeneity remains the word, with yields on the same plot showing a ratio of one to two,” consultancy Agritel said. Droughts set to cause late damage to EU rapeseed crop 2018-07-12T04:00:00Z This heterogeneity was probably a factor in the failure of the rindopepimut phase III trial. Immunotherapy offers a promising bet against brain cancer 2018-09-25T04:00:00Z Right now, in the face of America’s reactionary narrow-mindedness, the work’s insistent cross-cultural heterogeneity feels joyfully subversive. 'Made in L.A. 2018': Why the Hammer biennial is the right show for disturbing times 2018-06-05T04:00:00Z However, because of the considerable heterogeneity among autistic people, I think it could be helpful for them and their families—together with autism researchers, clinicians and relevant professionals—to discuss whether subtypes should be introduced. The Truth About Hans Asperger's Nazi Collusion 2018-05-17T04:00:00Z Yet in the absence of cultural and institutional supports, heterogeneity and trust are frequently in tension, as different ways of life give rise to suspicion and animosity. Opinion | Is the United States Too Big to Govern? 2018-05-11T04:00:00Z However, because of the considerable heterogeneity among autistic people, I think it could be helpful for them and their families — together with autism researchers, clinicians and relevant professionals — to discuss whether subtypes should be introduced. The truth about Hans Asperger’s Nazi collusion 2018-05-07T04:00:00Z The term spectrum also refers to the heterogeneity in autism. Is it Time to Give Up on a Single Diagnostic Label for Autism? 2018-05-04T04:00:00Z The work, while interesting, is “not entirely surprising,” said Deborah Caswell, a researcher at the Francis Crick Institute who studies tumor heterogeneity, particularly in lung cancer. Scientists Find Mini Gastrointestinal Tract Growing Inside Tumor 2018-03-29T04:00:00Z Although the Dems’ strength lies in its diversity and heterogeneity, we must urgently capitalize on that which binds us as one - our morality based on care, liberty, and fairness. Opinion | Democrats Are Primed for 2018 and Looking Pretty in 2020 2018-03-17T04:00:00Z Mac prefers when the audience reflects the heterogeneity of the nation. Taylor Mac on gay history, 'Hamilton' and his epic 24-hour extravaganza at the Ace 2018-03-14T04:00:00Z Most notable may be a sense of heterogeneity. For Sacramento, 'Lady Bird' offers a vivid portrait of a city that revels in its 'modest pleasures' 2018-03-01T05:00:00Z This heterogeneity is also part of what is meant by a spectrum. Is it Time to Give Up on a Single Diagnostic Label for Autism? 2018-05-04T04:00:00Z They conclude that Réunion magmas tap an unusually ancient, primitive source compared to other volcanic hotspots, which could offer a window into the formation and preservation of ancient heterogeneities in Earth's interior. Hadean silicate differentiation preserved by anomalous 142Nd/144Nd ratios in the Réunion hotspot source 2018-02-27T05:00:00Z However, with regard to oxide materials, there are challenges associated with the presence of chemical disorder and heterogeneities. The two faces of a magnetic honeycomb 2018-02-13T05:00:00Z For example, using this technique to investigate abnormal cellular growths that eventually progress to a malignant state would be a good choice for future studies into the origin and clonal heterogeneity of tumour cells. On the trail of invasive cells in breast cancer 2018-02-11T05:00:00Z Using a functional model of breast cancer heterogeneity, we previously showed that clonal sub-populations proficient at generating circulating tumour cells were not all equally capable of forming metastases at secondary sites1. Asparagine bioavailability governs metastasis in a model of breast cancer 2018-02-06T05:00:00Z In fact isn't the link between heterogeneity and social cohesion noted in any intro sociology textbook? Opinion | The Necessary Immigration Debate 2018-02-03T05:00:00Z Our results show that Réunion magmas tap into a particularly ancient, primitive source compared with other volcanic hotspots7,8,9,10, offering insight into the formation and preservation of ancient heterogeneities in Earth’s interior. Hadean silicate differentiation preserved by anomalous 142Nd/144Nd ratios in the Réunion hotspot source 2018-02-27T05:00:00Z Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer. Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes 2018-01-23T05:00:00Z Combined single-cell functional and gene expression analysis resolves heterogeneity within stem cell populations. From haematopoietic stem cells to complex differentiation landscapes 2018-01-23T05:00:00Z A model of breast cancer heterogeneity reveals vascular mimicry as a driver of metastasis. Asparagine bioavailability governs metastasis in a model of breast cancer 2018-02-06T05:00:00Z Targeted identification of short interspersed nuclear element families shows their widespread existence and extreme heterogeneity in plant genomes. Genome sequence of the progenitor of the wheat D genome Aegilops tauschii 2017-11-14T05:00:00Z Distinct evolution and dynamics of epigenetic and genetic heterogeneity in acute myeloid leukemia. BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation 2017-11-07T05:00:00Z Reconciling dynamic and seismic models of Earth’s lower mantle: the dominant role of thermal heterogeneity. Tidal tomography constrains Earth’s deep-mantle buoyancy 2017-11-14T05:00:00Z The inherent heterogeneity and asynchronous nature of the reprogramming process renders it difficult to study this process using bulk genomic techniques. Single-cell transcriptomics reconstructs fate conversion from fibroblast to cardiomyocyte 2017-10-24T04:00:00Z Miller, F. R., Miller, B. E. & Heppner, G. H. Characterization of metastatic heterogeneity among subpopulations of a single mouse mammary tumor: heterogeneity in phenotypic stability. Asparagine bioavailability governs metastasis in a model of breast cancer 2018-02-06T05:00:00Z As a further layer of heterogeneity in Xi expression, we find a unique pattern for TIMP1. Landscape of X chromosome inactivation across human tissues : Nature : Nature Research 2017-10-10T04:00:00Z “I think my work is about heterogeneity,” he says. Taylor Mac on queering history: 'Someone like me doesn't normally get to represent America' 2017-09-12T04:00:00Z Even as its status as one of the most diverse cities in the country is threatened by tech-boom-era gentrification, its vibrant cultural heterogeneity remains its greatest strength. null 2017-09-12T04:00:00Z Still, considerable molecular and clinical heterogeneity has been demonstrated11, 40, suggesting that currently defined MB subgroups are likely to be an oversimplification of true molecular substructure. The whole-genome landscape of medulloblastoma subtypes : Nature : Nature Research 2017-07-18T04:00:00Z In the case of vector-borne diseases, local heterogeneity is high owing to a variety of factors such as mosquito population abundance, human–mosquito interactions, and control interventions67, 68, 69, 70, 71, 72. Genomic epidemiology reveals multiple introductions of Zika virus into the United States : Nature : Nature Research 2017-05-23T04:00:00Z We show that XCI at 683 X-chromosomal genes is generally uniform across human tissues, but identify examples of heterogeneity between tissues, individuals and cells. Landscape of X chromosome inactivation across human tissues : Nature : Nature Research 2017-10-10T04:00:00Z But when we do this, it does not capture the heterogeneity of the disease. Wanted: More Data, the Dirtier the Better 2017-06-12T04:00:00Z What looks like heterogeneity right now might turn into a homogenous world where consultants rule the foreign policy roost. Analysis | The traditional think tank is withering. In its place? Bankers and consultants. 2017-04-06T04:00:00Z HERROD: The future, as the past has always been, is heterogeneity. Three VCs on What’s Next in Technology 2017-03-07T05:00:00Z The German structural imbalance in trade with the rest of the E.U. and the U.S. underscores the economic heterogeneity within the E.U. — ergo, this is a multilateral deal in bilateral dress.” Trump’s administration has a new target on trade — and it’s not China or Mexico 2017-01-31T05:00:00Z Considerable heterogeneity exists in the general rubric of ALS. Decoding ALS: from genes to mechanism : Nature : Nature Research 2016-11-08T05:00:00Z The biggest difference is that our group ignores heterogeneity across data sets, whereas in traditional meta-analysis we are taught to reduce heterogeneity. Wanted: More Data, the Dirtier the Better 2017-06-12T04:00:00Z Mess, heterogeneity, is bad — the opposite impulse of artistic minimalism. The Oppressive Gospel of ‘Minimalism’ 2016-07-26T04:00:00Z “The heterogeneity brought about by quotas has enhanced the quality of boardroom deliberations and overall corporate governance,” he wrote. The weird thing that happens when you put more women in the boardroom 2016-05-24T04:00:00Z Indeed, given the apparent heterogeneity of IBS, many scientists agree that it seems far-fetched to imagine that any one animal model will ever tell the full story. Microbiome: Bacterial broadband : Nature : Nature Publishing Group 2016-05-17T04:00:00Z No other human disease is known to possess this degree of genetic heterogeneity. The Improvisational Oncologist 2016-05-12T04:00:00Z And if we found a signal, despite the heterogeneity, wouldn’t you then say, oh, that’s what I should be looking at? Wanted: More Data, the Dirtier the Better 2017-06-12T04:00:00Z This is particularly important in neuroscience, says Rouleau, where progress is slowed by both the vast complexity of the brain and the heterogeneity of neurological diseases. Data sharing: Access all areas : Nature : Nature Publishing Group 2016-05-10T04:00:00Z Yet despite its heterogeneity, the groups still live in somewhat segregated communities. Radicalization of a Belgium Student Turned Bomb Maker Was Invisible 2016-04-08T04:00:00Z The sequencing of tumour genomes has revealed heterogeneity not only among cancers and patients, but in a single tumour. Back to Earth 2016-02-16T05:00:00Z America also retained a high degree of social and cultural heterogeneity in its communities. Trump’s America 2016-02-12T05:00:00Z Using dirty data allows you to account for clinical heterogeneity. Wanted: More Data, the Dirtier the Better 2017-06-12T04:00:00Z As the economists Alberto Alesina and Edward Glaeser put it in an important paper, European countries are much more generous to the poor relative to the United States mainly because of American racial heterogeneity. Racial Identity, and Its Hostilities, Return to American Politics 2016-01-05T05:00:00Z Brain cancers classified as a single subtype, in fact, contain cells from multiple subtypes of cancer, and this heterogeneity means that treatments are more likely to fail. With Cancer, Forgetting the Stakes Becomes Its Own Disease 2015-11-30T05:00:00Z But given the heterogeneity of women’s interests, we need to look beyond numbers to ensure there is also a greater diversity of female voices: one woman’s voice is not the equivalent of another’s. Hurrah for female bosses, but let’s not forget their cleaners | Sonia Sodha 2015-10-31T04:00:00Z “Diversity and heterogeneity is the new structure of urban society,” the authors conclude. Which is the world's most segregated city? 2015-10-28T04:00:00Z What I’m saying is, don’t worry about the heterogeneity. Wanted: More Data, the Dirtier the Better 2017-06-12T04:00:00Z This is perhaps unsurprising given expected locus and allelic heterogeneity, and modest sample size40. The UK10K project identifies rare variants in health and disease : Nature : Nature Publishing Group 2015-09-13T04:00:00Z “Normally you expect differentiation by latitude … but that doesn’t explain the huge heterogeneity within a latitude,” William Grundy of Lowell Observatory told a press briefing earlier today. New Horizons Delivers First Close-up Glimpse of Pluto and Charon 2015-07-15T04:00:00Z Local firms tend to dominate the market, especially for products of low market heterogeneity and low manufacturing complexity, as highlighted in research by my colleagues Sea-Jin Chang and Sam Park. Is The Good Enough Market Attractive Enough? 2015-06-10T04:00:00Z Why it is hard to answer Colorectal cancer shows a high degree of heterogeneity in mutations, both between and within individual tumours. Colorectal cancer: 5 big questions : Nature : Nature Publishing Group 2015-05-12T04:00:00Z When asking questions about culture and facial expressions, she says, historical heterogeneity provides “another axis we should be thinking about.” What your smile says about where you’re from 2015-05-05T04:00:00Z That means there are some heterogeneities along the base of the Himalayas that are modulating the slip in these very large earthquakes. Dire Prospects Seen When the Full Nepal Earthquake Death Toll is Tallied 2015-04-29T04:00:00Z The geographic isolation of small groups breeds heterogeneity, both of dialects and of language isolates, as it probably did among Paleolithic hunters. Can Dying Languages Be Saved? 2015-03-23T04:00:00Z Full understanding of the factors contributing to mutational heterogeneity in cancer genomes thus requires the evaluation of the relationship between multiple epigenetic marks and mutation patterns in a cell-type-specific manner. Cell-of-origin chromatin organization shapes the mutational landscape of cancer : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Zweig savoured the pluralistic nature of his character – just as he relished nothing more in his writing and his travels than humanity’s own heterogeneity. The Real-Life Muse Behind Wes Anderson's 'Grand Budapest Hotel' 2015-02-17T05:00:00Z They hit upon something called historical heterogeneity, which captures the history of a country’s migrations in a single number. What your smile says about where you’re from 2015-05-05T04:00:00Z They are characterized by phenotypic, aetiological, biological and clinical heterogeneity. Comprehensive genomic characterization of head and neck squamous cell carcinomas : Nature : Nature Publishing Group 2015-01-27T05:00:00Z Describing the heterogeneity of a winter 1865 gathering, one reporter glowed: “The crowd here symbolizes the nation.” New Year’s in the Lincoln White House 2015-01-01T05:00:00Z This, combined with diagnostic 'noise' — that is, the heterogeneity and misdiagnosis of people with MDD — drives up the number of subjects needed to find significant genetic associations. Mental health: Depression needs large human-genetics studies 2014-11-11T05:00:00Z In ecosystems with a recent paucity of burning, fire management that fosters burning under diverse conditions may be useful for achieving this desired heterogeneity and reducing fuel accumulations41. Learning to coexist with wildfire : Nature : Nature Publishing Group 2014-11-04T05:00:00Z Instead we ask detailed questions about causality, robustness, bias, heterogeneity, external validity, etc. Enough Already With The Sweeping Claims That Economics Is Unscientific 2014-09-28T04:00:00Z According to this idea, genetic heterogeneity allows bodies to be more adaptive and resilient. Garbled DNA Might Be Good for You 2014-09-12T04:00:00Z This heterogeneity of product characteristics outside of molecule design is a larger driver of quality differences for manufacturers of larger molecules than for smaller ones. Preventing A Dangerous Race To The Bottom In Biotechnology 2014-08-17T04:00:00Z There are wide differences in the ability of various ethnic groups and individuals to clear medications from the bloodstream because of heterogeneity in the activity of the enzymes that metabolize drugs. Better Clinical Trial Designs Could Lower Development Costs And Yield More New Drugs 2014-08-13T04:00:00Z The many organisms and propagules that may survive the fire, combined with heterogeneity in age, structure and species composition across landscapes, confer resilience against shifts to non-forest types. Learning to coexist with wildfire : Nature : Nature Publishing Group 2014-11-04T05:00:00Z The exciting thing for investors and entrepreneurs alike is the abundance of opportunities due to the heterogeneity of innovation today. EYVoice: Jeff Fagnan Of Atlas Venture On Surviving The Start-Up Rollercoaster 2014-08-07T04:00:00Z We show that the use of alternative ascertainment and diagnostic schemes designed to rapidly increase sample size does not inevitably introduce a crippling degree of heterogeneity. Biological insights from 108 schizophrenia-associated genetic loci : Nature : Nature Publishing Group 2014-07-21T04:00:00Z The new robust integration fabrics that are event enabled, in memory-in motion, become great enablers that can embrace the heterogeneity of legacy, cloud, sensors, GPS, functional packages, customers, suppliers and employees. Secrets Of The Greatest CIO For Hire In History 2014-07-07T04:00:00Z This environmental heterogeneity encompasses extensive variation in the onset, season and intensity of flowering35. The genome of Eucalyptus grandis : Nature : Nature Publishing Group 2014-06-10T04:00:00Z “Innovation loves diversity and heterogeneity…be it gender, ethnicity, or culture. Our main challenge now is to create more Haredi startup success stories,” said the economy ministry’s chief scientist Avi Hasson. With a Bit of Faith, Religious Tech Entrepreneurs Hope to Make a Splash - Digits - WSJ 2014-05-16T04:00:00Z However, we need to apply this doubt to the data itself – keeping spatial heterogeneity and other sources of variability in mind. Which bacteria are in my poop? It depends where you look... 2014-05-12T12:00:30Z Yet in this small nation there is at least some increasingly notable heterogeneity. Latvia Watches Nervously As Putin Seeks to Exert Power 2014-05-05T17:19:35Z Although such consortium approaches are desirable, investigators should be mindful of systematic differences among cohorts stemming from technical biases, population stratification, and genetic and phenotype heterogeneity. Guidelines for investigating causality of sequence variants in human disease 2014-04-23T17:21:03.147Z This was probably due to the heterogeneity of day-9 mitochondria. Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans 2014-04-04T22:52:36.299Z Favouring this possibility, genetically distinct subclones cooperatively enhanced tumour growth in models engineered to recapitulate a form of tumour cell heterogeneity identified in brain cancers. Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers 2014-04-04T18:28:38.990Z Pericytes can be constricted and dilated by neurotransmitters in vitro, through poorly understood signalling pathways, and capillary blood flow heterogeneity might reflect differences in pericyte tone. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z These observations provide a rational strategy to overcome the multifaceted clonal heterogeneity that emerges when tumors are treated with targeted agents. [Research Articles] Blockade of EGFR and MEK Intercepts Heterogeneous Mechanisms of Acquired Resistance to Anti-EGFR Therapies in Colorectal Cancer 2014-02-19T19:26:02.687Z In particular, for many diseases there is overwhelming evidence that both locus and allelic heterogeneity is high, such as in autism, epilepsy and schizophrenia. Guidelines for investigating causality of sequence variants in human disease 2014-04-23T17:21:03.147Z We used this approach to profile ~90 proteins in cells from FNAs and subsequently map patient heterogeneity at the protein level. [Research Articles] Cancer Cell Profiling by Barcoding Allows Multiplexed Protein Analysis in Fine-Needle Aspirates 2014-01-15T19:25:17.496Z In the case of human breast cancer, recent studies highlight the phenotypic and genetic diversity present locally within individual tumours, but whether this heterogeneity is a cause or a consequence of tumour progression remains unclear. Tumour cell heterogeneity maintained by cooperating subclones in Wnt-driven mammary cancers 2014-04-04T18:28:38.990Z Such stochasticity in transcription increases the heterogeneity among cells and likely contributes to the phenotypic variance among individuals of identical genotype. [Report] Single-Cell RNA-Seq Reveals Dynamic, Random Monoallelic Gene Expression in Mammalian Cells 2014-01-09T18:56:54.368Z Intratumoral heterogeneity contributes to cancer drug resistance, but the underlying mechanisms are not understood. [Report] Targeted Therapy Resistance Mediated by Dynamic Regulation of Extrachromosomal Mutant EGFR DNA 2014-01-02T19:26:29.255Z A study design that assumes low locus and allelic heterogeneity would be certain to fail for these conditions, and this fact would be revealed by even casual evaluations of power for reasonable genetic models. Guidelines for investigating causality of sequence variants in human disease 2014-04-23T17:21:03.147Z Ironically, it was only in the diaspora that he came to appreciate the linguistic and religious heterogeneity of his own homeland. Ramachandra Guha on why Gandhi remains globally relevant 2013-12-24T01:59:25Z “I think it is becoming apparent that intra-tumor heterogeneity is one of several major impediments to personalized cancer treatment by single ‘magic bullet’ chemotherapies,” Schaffer said. Evolution of an Individual's Cancer Can Be Tracked Cell by Cell 2013-11-15T17:45:04.163Z “It is important to measure and analyze this heterogeneity because it can have important implications for aggregate figures.” Economists Discover the Poor Behave Differently From the Rich 2013-11-07T23:58:36Z But they all quickly realized that IT heterogeneity is what customers want. Hybrid Cloud? It's About Choice. 2013-10-21T13:07:00Z Our analysis provides the lower bound for tumour heterogeneity, because only coding mutations were used for clustering. Mutational landscape and significance across 12 major cancer types 2013-10-16T17:22:05.383Z Each simulated data set therefore contained identical numbers of sites and taxa to the observed alignment; and because we fitted a mixture model, sites’ heterogeneity parameters should reflect heterogeneity in the observed sequences. Genome-wide signatures of convergent evolution in echolocating mammals 2013-10-09T17:21:23.207Z “Understanding tumor heterogeneity will hopefully help end the problem of disease recurrence,” Ried said. Evolution of an Individual's Cancer Can Be Tracked Cell by Cell 2013-11-15T17:45:04.163Z Flynn saw a surprising heterogeneity in lung pathology among individual monkeys — and even within the same individual. Latency: A sleeping giant 2013-10-09T17:21:03.410Z The earthquake ruptured along a fault over 180-kilometer-long and structural heterogeneity resulted in a massive release of stress from the subducting slab. [Report] Deep-Focus Earthquake Analogs Recorded at High Pressure and Temperature in the Laboratory 2013-09-19T17:56:47.773Z However, disseminated cancer cells that remain after 'curative' surgery exhibit extreme genomic heterogeneity before the manifestation of metastasis. Selection and adaptation during metastatic cancer progression 2013-09-18T17:22:42.817Z Inter- and intratumour heterogeneity pose a challenge to personalized cancer medicine because a single needle biopsy or surgical excision is unlikely to accurately capture the complete genomic landscape of a patient's cancer. Tumour heterogeneity in the clinic 2013-09-18T17:22:34.247Z In light of immense tumour heterogeneity, it is unclear how and when to clinically evaluate tumour heterogeneity. Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z We focus on the role of genomic instability in generating inter- and intratumour heterogeneity, and review the array of instability mechanisms observed in cancer and their contribution to tumour evolution. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z To what extent do metastasis, therapy resistance and disease progression reflect the intrinsic properties of cancer stem cells as opposed to genetic evolution or other sources of heterogeneity? Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z This heterogeneity is later reduced by selected clonal expansion, suggesting that the disseminated cells had yet to acquire key traits of fully malignant cells. Selection and adaptation during metastatic cancer progression 2013-09-18T17:22:42.817Z Their integration into the aforementioned clinical-trial design frameworks that focus on interpatient tumour heterogeneity is possible but would necessitate that the frameworks become dynamic models that consider changes across space and time within individuals. Tumour heterogeneity in the clinic 2013-09-18T17:22:34.247Z Accurately modelling tumour complexity and heterogeneity poses a significant challenge. Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z During linear evolution, if a new clone fails to outcompete its predecessor, or predecessors, a degree of heterogeneity will be observed. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z The cancer stem-cell model provides one explanation for the phenotypic and functional heterogeneity among cancer cells in some tumours. Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z In light of these observations and the multilevel complexity and heterogeneity of systemic cancer in particular, focusing merely on individual genetic alterations and corresponding targeted therapies is unlikely to be the most promising approach. Selection and adaptation during metastatic cancer progression 2013-09-18T17:22:42.817Z These samples, in addition to other biorepositories such as tissue banks and autopsy programmes, provide a means to build knowledge bases that help us to gain insight into complex molecular events such as intratumour heterogeneity. Tumour heterogeneity in the clinic 2013-09-18T17:22:34.247Z How does the genetic and phenotypic variation that exists within tumours, or intratumoral heterogeneity, influence tumour growth? Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z There is considerable heterogeneity in both the patterns and extent of genomic instability that are prevalent in different tumour types. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z In these circumstances it is not necessarily clear which phenotypic and functional differences among cells arise from which sources of heterogeneity. Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z In summary, benign lesions share DNA methylation changes, restricted loss of heterogeneity and multiple oncogenic mutations with malignant lesions, but they are insufficient to predispose lesions to invasion and metastasis. Selection and adaptation during metastatic cancer progression 2013-09-18T17:22:42.817Z Exploring the impact of intratumour heterogeneity in a therapeutic context adds a further layer of complexity. Tumour heterogeneity in the clinic 2013-09-18T17:22:34.247Z Figure 1: Origins and influence of tumour heterogeneity. Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z Whatever the explanation, these observations suggest that not all forms of genetic heterogeneity are equal in terms of their impact on patient outcome. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z Integration of results from multiple experimental approaches will be necessary to distinguish the relative contributions of these sources of heterogeneity to disease progression. Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z Furthermore, sequencing studies revealing genomic heterogeneity in primary tumours and metastases suggest that several attractor states may exist for a given cancer. Selection and adaptation during metastatic cancer progression 2013-09-18T17:22:42.817Z Given the complexity of intratumour heterogeneity and clonal evolution, it is impossible to provide approaches that are universally applicable. Tumour heterogeneity in the clinic 2013-09-18T17:22:34.247Z Conceivably, distinct environmental landscapes within a given tumour select for mutations that engender survival and expansion, thereby creating tumour cell heterogeneity. Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z However, it is important to note that phenotypic heterogeneity is not only mediated through genetic diversity. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z Nonetheless, if the genetic heterogeneity involves mutations that influence cancer cell phenotype or function, the genetic heterogeneity will contribute to tumour heterogeneity through mechanisms independent of cancer stem cell differentiation. Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z This Insight covers some of the key topics relevant to the fast-moving field of cancer research, ranging from the basic understanding of tumour heterogeneity to translational cancer research and clinical trials. Tumour heterogeneity 2013-09-18T17:21:11.727Z The aim of this study is to genomically evaluate all archived tumour samples from a cohort of molecularly profiled patients to assess heterogeneity and clonal evolution. Tumour heterogeneity in the clinic 2013-09-18T17:22:34.247Z The targeting of multiple tumour compartments may represent a solution to avoid resistance and achieve durable patient responses; however, elucidating the relationship between tumour heterogeneity and therapeutic response is still a significant challenge. Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z In addition, there is a need to develop clinically useful measures of heterogeneity. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z As we develop a more complete understanding of genetic heterogeneity within tumours, there may be some cancers in which genetic heterogeneity is the main driver of phenotypic and functional heterogeneity. Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z Here, we consider the heterogeneity in development and phenotype of memory B cells and whether particular functions are partitioned into distinct subsets. [Special Issue Review] Diversity Among Memory B Cells: Origin, Consequences, and Utility 2013-09-12T17:56:44.660Z Subpopulations of cancer cells with unique genomes in the same patient may exist across different geographical regions of a tumour or evolve over time, called intratumour heterogeneity. Tumour heterogeneity in the clinic 2013-09-18T17:22:34.247Z In this Review, we briefly define the tumour cell extrinsic compartments and discuss how they contribute to tumour heterogeneity. Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z Both mathematical and experimental modelling approaches are also likely to inform our understanding of how heterogeneity affects tumour progression. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z Nonetheless, if the genetic heterogeneity involves mutations that influence cancer cell phenotype or function, the genetic heterogeneity will contribute to tumour heterogeneity through mechanisms independent of cancer stem cell differentiation. Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z Our study sampled a single site of the primary tumour, in a disease with a potentially high level of tumour heterogeneity. Comprehensive molecular characterization of clear cell renal cell carcinoma 2013-07-03T17:20:51.807Z Here, we review the clinical implications of interpatient and intratumour heterogeneity for cancer diagnosis, making a prognosis, treatment selection and resistance. Tumour heterogeneity in the clinic 2013-09-18T17:22:34.247Z In addition, these studies do not account for tumour heterogeneity. Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z This heterogeneity affects key cancer pathways, driving phenotypic variation, and poses a significant challenge to personalized cancer medicine. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z It is time to critically test the model and its predictions, to acknowledge when the data do not fit the model and to integrate the data with other sources of heterogeneity when they do. Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z This may reflect stromal or endothelial cell contributions, or tumour cell heterogeneity. Comprehensive molecular characterization of clear cell renal cell carcinoma 2013-07-03T17:20:51.807Z To prospectively assess geographical or spatial heterogeneity, profiling of multiregional tumour samples would be indicated. Tumour heterogeneity in the clinic 2013-09-18T17:22:34.247Z As discussed, the complexity of the tumour is a result of continuous crosstalk between the tumour cells and the environment over time, adding the complication of temporal heterogeneity on top of spatial heterogeneity. Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z A major cause of genetic heterogeneity in cancer is genomic instability. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z New models of cancer heterogeneity and plasticity may emerge. Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z But the longer the fighting goes on, so the diversity and heterogeneity of the opposition becomes clearer. Gruesome Syria video pinpoints West's dilemma 2013-05-14T10:47:49Z Current efforts are focused on gathering evidence to support the idea that intratumour heterogeneity substantially affects disease outcome, although the relationship is probably context dependent. Tumour heterogeneity in the clinic 2013-09-18T17:22:34.247Z A more comprehensive understanding of heterogeneity within the tumour cell extrinsic compartments and how this influences resistance development will expand our understanding of treatment responses. Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z This emphasizes again the heterogeneity of the euro area which is one of the main challenges of the ECB. Eurozone unemployment hits new high 2013-04-30T18:14:00Z It will also be crucial to integrate our understanding of the biology of these cells with our understanding of other sources of heterogeneity, to develop a realistic view of how each contributes to disease progression. Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z The growing number of solved structures provides a framework to now interpret such functional heterogeneity, paving the path towards personalized medicine and hence improving human health. Molecular signatures of G-protein-coupled receptors 2013-02-13T18:21:29.900Z Surgical resections of primary tumours or metastatic lesions provide large volumes of tumour tissue that are required for assessment of regional heterogeneity and clonal diversity. Tumour heterogeneity in the clinic 2013-09-18T17:22:34.247Z Conversely, the FEM variance data are a complex four-body data set that is rich with details about spatial heterogeneity but is difficult to invert into a specific structure. [Technical Response] Response to Comment on “The Local Structure of Amorphous Silicon” 2012-12-20T21:25:57.750Z There’s a lot of heterogeneity so there are hundreds of different prostate cancers or breast cancers and people need to know what kind of cancer they have. Top CEOs Share how Big Data is Transforming our Health, Wealth and Security 2012-12-17T16:04:03Z Phenotypic and functional heterogeneity arise among cancer cells within the same tumour as a consequence of genetic change, environmental differences and reversible changes in cell properties. Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z The heterogeneity of mood disorders further complicates the pinpointing of precise circuit dysfunctions mediating symptoms of depression. The dopamine side(s) of depression 2012-12-17T15:15:03.510Z Last, intratumour heterogeneity and clonal evolution occur and there are feasible technologies to measure these phenomena in the clinical setting. Tumour heterogeneity in the clinic 2013-09-18T17:22:34.247Z To deconvolute cellular heterogeneity and detect subtle genomic aberrations, we introduced an algorithm based on tumor cellularity to increase the comparability of copy number profiles between samples. [Research Articles] Quantitative Image Analysis of Cellular Heterogeneity in Breast Tumors Complements Genomic Profiling 2012-10-28T19:57:21.520Z In EMs, heterogeneity in inflation allows us to divide the sample in “high” and “low” inflation episodes. Jobless recoveries: Labour lost 2012-10-25T18:02:19Z In this Review, we evaluate the implications of these new data for the cancer stem-cell model and the extent to which this model accounts for clinically important forms of heterogeneity in cancer. Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z Improved integrative models, based on research in the behavioral, social, and neurosciences, are urgently needed that better reflect the heterogeneity and complexity of mood disorders. [Editorial] The Burden of Mood Disorders 2012-10-04T17:55:05.150Z “What amazes me is the heterogeneity,” he says. Trio of Genome-Sequencing Studies Offer a Broader View of Lung Cancer 2012-09-13T21:45:00.287Z These findings enhance our understanding of the genomic complexity and heterogeneity underlying medulloblastoma, and provide several potential targets for new therapeutics, especially for Group 3 and 4 patients. Dissecting the genomic complexity underlying medulloblastoma 2012-08-01T17:52:34.853Z However, the accrual of large numbers of patients and the use of comprehensive sequencing and gene expression approaches will be required because of the extreme genomic heterogeneity documented by this investigation. Whole-genome analysis informs breast cancer response to aromatase inhibition 2012-06-20T17:22:05.433Z The utility of weighting trials according to LDL reduction is not that it maintains the equivalence of randomization, it is that it helps to neutralize the heterogeneity in the overall statin meta-group. Fascinating Debate Over Statins For Primary Prevention 2012-05-30T17:22:15Z While an aggregate evolves, not only the matter composing it, but also the motion of that matter, passes from an indefinite, incoherent homogeneity to a definite, coherent, heterogeneity. A Review of the Systems of Ethics Founded on the Theory of Evolution 2012-03-17T02:01:00.033Z The second reason relates to a growing appreciation of the heterogeneity of 'common' diseases. The great beyond 2012-02-29T18:20:03.553Z It is the most common malignant brain tumour in children, and shows tremendous biological and clinical heterogeneity. Dissecting the genomic complexity underlying medulloblastoma 2012-08-01T17:52:34.853Z If we turn to its functions, we find these similarly show an ever-increasing inter-dependence, an augmentation in number and heterogeneity, and a greater precision. Herbert Spencer 2012-02-29T03:00:20.773Z When things are too homogeneous she breaks them up into new and amazing kinds of heterogeneity. The Gentle Reader 2012-02-15T03:00:37.463Z With this increase of definiteness and coherence goes also an increase of heterogeneity; the moral man performs more varied duties, adjustments of acts to ends in more varied relations, than does the immoral man. A Review of the Systems of Ethics Founded on the Theory of Evolution 2012-03-17T02:01:00.033Z These devastating mitochondrial disorders are characterized by phenotypic and genetic heterogeneity, with more than 100 causal genes identified to date. [Research Articles] Molecular Diagnosis of Infantile Mitochondrial Disease with Targeted Next-Generation Sequencing 2012-01-25T20:25:04.410Z Both ALL and AML share common features of clonal heterogeneity at presentation followed by dynamic clonal evolution at relapse, including the addition of new mutations that may be relevant for relapse pathogenesis. Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing 2012-01-25T18:51:09.287Z Thus Evolution and Dissolution appeared "under their primordial aspects," and differentiations, with resulting increase of heterogeneity, were seen to be secondary not primary traits of evolution. Herbert Spencer 2012-02-29T03:00:20.773Z Alas for the ill-fated pundit who, forgetting his aim, flounders in the bottomless morass of heterogeneity. The Gentle Reader 2012-02-15T03:00:37.463Z And while approaching this goal, society is ever acquiring in its economic structure both greater heterogeneity and greater specialization. A Review of the Systems of Ethics Founded on the Theory of Evolution 2012-03-17T02:01:00.033Z One is that lessening of the reciprocal sentiment of collective responsibility which the complex heterogeneity of the modern State involves. The Great Illusion A Study of the Relation of Military Power to National Advantage 2012-01-11T03:00:19.077Z Mesozoic marine tetrapod diversity: mass extinctions and temporal heterogeneity in geological megabiases affecting vertebrates. Rigid Swimmer and the Cretaceous Ichthyosaur Revolution (part I) 2012-01-03T23:45:00.273Z Thus arise differentiations of structure, a transition from a uniform to a multiform state, a passage from homogeneity to heterogeneity, and this must go on cumulatively. Herbert Spencer 2012-02-29T03:00:20.773Z The goal now, says Anderson, is to combine these methods of molecular analysis to provide a clearer picture of the genome's heterogeneity. Genetics: Profiling a shape-shifter 2011-12-14T18:21:12.203Z The result of greater and greater heterogeneity is to produce a new principle, which combines the warring elements. A Review of the Systems of Ethics Founded on the Theory of Evolution 2012-03-17T02:01:00.033Z The physical heterogeneity may be seen at all exposures, and is illustrated in Plate XXXV. The Geography of the Region about Devils Lake and the Dalles of the Wisconsin 2011-11-29T03:00:17.347Z African slavery dying out in the north, but prospering in the south, was this heterogeneity. The Brothers' War 2011-11-01T02:00:24.007Z Thus there is an almost continuous movement towards heterogeneity. Herbert Spencer 2012-02-29T03:00:20.773Z The removal of rubrimaculatus from the western complex results in a more homogeneous remainder and does not greatly increase the heterogeneity of the eastern complex. A Taxonomic Revision of the Leptodactylid Frog Genus Syrrhophus Cope 2011-10-23T02:00:22.253Z “There is a great heterogeneity in the behavior of these tumors,” Hicks said in a telephone interview. Jobs’s Apple Exit Follows Eight-Year Health Fight After Cancer 2011-08-25T21:36:03Z The heterogeneity of the drift arising from the diverse nature of the rocks which contributed to it is lithological heterogeneity—a term which implies the commingling of materials derived from different rock formations. The Geography of the Region about Devils Lake and the Dalles of the Wisconsin 2011-11-29T03:00:17.347Z In the preceding chapter I have spoken about the heterogeneity of the Japanese as a race. An Introduction to the History of Japan 2011-08-25T02:00:29.177Z But how is that kind of heterogeneity insured which is required to carry on life? Herbert Spencer 2012-02-29T03:00:20.773Z At South Side, the district believes in heterogeneity throughout. A tale of two schools: Who?s to blame for the differences? 2011-08-22T14:30:00Z FL is an indolent and typically incurable disease characterized by clinical and genetic heterogeneity. Frequent mutation of histone-modifying genes in non-Hodgkin lymphoma 2011-08-17T17:21:43.793Z Lithological heterogeneity is one of the notable characteristics of glacial formations. The Geography of the Region about Devils Lake and the Dalles of the Wisconsin 2011-11-29T03:00:17.347Z The superiority of animals to plants and metals in the possession of special organs of sense is connected with the greater complexity and heterogeneity of their structure. Encyclopaedia Britannica, 11th Edition, Volume 10, Slice 1 "Evangelical Church Conference" to "Fairbairn, Sir William" 2011-07-16T02:00:16.387Z First there is heterogeneity among progenitors which "generates new deviations by composition of forces"; in other words new patterns arise from the mingling of diverse hereditary contributions in fertilisation. Herbert Spencer 2012-02-29T03:00:20.773Z With every additional pulse, more heterogeneities in the heart are activated and gradually suppress the chaotic activity and "reprogram" the heart. New Method Defibrillates Heart With Less Electricity, Pain 2011-07-15T14:21:00Z "Those who question the viability of the euro area as a single currency area on the grounds of economic heterogeneity are misguided," Mr. Trichet said in a lecture at the London School of Economics. Trichet Draws U.S.-EU Comparison 2011-06-13T19:04:56Z It follows that this double heterogeneity constitutes a feature which can be utilized in determining the former extension of existing glaciers, as well as the former existence of glaciers where glaciers do not now exist. The Geography of the Region about Devils Lake and the Dalles of the Wisconsin 2011-11-29T03:00:17.347Z I at once set aside the ordinary orchestra because of its heterogeneity, with its groups of string, wood, brass, and percussion instruments. An Autobiography 2011-05-21T02:00:10.850Z Development.—Growth is increase in bulk, development is increase in structure, and Spencer's chief induction in regard to development is that we see a change from an incoherent, indefinite homogeneity to a coherent, definite heterogeneity. Herbert Spencer 2012-02-29T03:00:20.773Z It should be noted that given the possibility of many confounding variables owing to the heterogeneity and size of our cohort, these observations will need to be substantiated using larger, independent cohorts in the future. Enterotypes of the human gut microbiome 2011-05-11T17:21:02.573Z A potential cell bank would need to decide how to handle such heterogeneity, because it affects the potential uses of a cell line. California ponders cell-banking venture 2011-04-27T17:20:29.863Z Another characteristic of the drift is its physical heterogeneity. The Geography of the Region about Devils Lake and the Dalles of the Wisconsin 2011-11-29T03:00:17.347Z The new methods and the willingness to tackle human Mendelian genetics, with attention to modifiers and heterogeneity, will enable the realization of the impact of genomics in genetics. [Essay] Genome-Sequencing Anniversary: Bringing Genomics and Genetics Back Together 2011-02-03T19:25:49.703Z No one can doubt that development is progressive differentiation, but it is rather a realisation of a complex inheritance of materialised potentialities than a change from an incoherent, indefinite homogeneity to a coherent, definite heterogeneity. Herbert Spencer 2012-02-29T03:00:20.773Z Across countries, urbanization and ethnic heterogeneity increase the frequency of riots. Economix: It's Always the Urban Pot That Boils Over 2011-02-01T11:00:40Z They were surprised by the chemical heterogeneity of the fibers, which hints at how organisms modulate chemistry at the nanoscale. Cracking a Tooth 2011-01-13T17:53:00Z Since lithological and physical heterogeneity are characteristics of glacial drift, they together afford a criterion which is often of service in distinguishing glacial drift from other surface formations. The Geography of the Region about Devils Lake and the Dalles of the Wisconsin 2011-11-29T03:00:17.347Z This heterogeneity is due to the facts that HCV replicates at a high rate and the viral polymerase, which makes copies of the RNA genome, is prone to error. Triple-Drug Cocktail in the Works for Hepatitis C Therapy 2011-01-05T22:16:21.493Z With advancing integration there went that advancing heterogeneity implied by inclusion of the several classes of inorganic phenomena and the several classes of super-organic phenomena in the same category with organic phenomena. Herbert Spencer 2012-02-29T03:00:20.773Z For the purpose he would make a few remarks as a basis of his "so-to-speak destructive construction of this social heterogeneity." The Song of Songs 2011-01-01T03:00:25.907Z Bill Bishop, author of "The Big Sort," adds that the heterogeneity of state, as opposed to city, electorates makes policy achievement extremely difficult. Why would a mayor ever want to be a governor? 2010-10-05T01:01:00Z This heterogeneity cannot fail to attract the attention of one examining any of the many exposures of drift about Baraboo at road gradings, or in the cuts along the railway. The Geography of the Region about Devils Lake and the Dalles of the Wisconsin 2011-11-29T03:00:17.347Z This diversity in thinking and action is reflected in the heterogeneity of their leadership team and how they make and execute their decisions. Do Multinationals Really Understand Globalization? 2010-08-06T18:06:00Z “Devonian landscape heterogeneity recorded by a giant fungus.” Bubbles, Bread and Beer 2010-06-23T11:40:00Z This is, after all, a country of near-impossible heterogeneity, with 22 official languages, scores of caste groups and representation by virtually every major religion in the world. Letter from India: Evidence of Tolerance: Clashes Are Rare 2010-02-25T11:50:00Z Thus, the heterogeneity of the Family Fringillidae, as now recognized, is emphasized by differences in the muscle patterns of the leg. Myology and Serology of the Avian Family Fringillidae A Taxonomic Study To deny this qualitative heterogeneity is to reduce the struggles and difficulties of life, its comedies and tragedies to illusion: to the non-being of the Greeks or to its modern counterpart, the "subjective." Creative Intelligence Essays in the Pragmatic Attitude Besides heterogeneity of tenure and jurisdiction in the borough, there was also heterogeneity of status; there were burh-thegns and cnihts, mercatores, burgesses of various kinds, the three groups representing perhaps military, commercial and agricultural elements. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 3 "Borgia, Lucrezia" to "Bradford, John" But the true view is that the State, as an organism, is a unity which contains heterogeneity. A Critical History of Greek Philosophy Evolution, as he tells us, is a change from homogeneity to heterogeneity, from a simple to a complex. The Vagabond in Literature The heterogeneity of the Family Fringillidae has been emphasized by many authors. Myology and Serology of the Avian Family Fringillidae A Taxonomic Study The existence of genuine connexions of all manner of heterogeneity cannot be doubted. Creative Intelligence Essays in the Pragmatic Attitude For the huge heterogeneity of the modern age, whose only common bond is usefulness, is nowhere so pitifully exposed against the dignity and hidden power of reticent beauty, as in Japan. The Spirit of Japan Calling it, merely for the moment, electricity, we know that all experimental analysis of electricity has given, as an ultimate result, the principle, or seeming principle, heterogeneity. Eureka: A Prose Poem In this kaleidoscopic vortex of phantasmal images were occasional snap-shots, if one might use the term, of singular clearness but unaccountable heterogeneity. The Shunned House And the lapse into heterogeneity of temperature, so obvious in this extreme case, is ever taking place more or less in all cases. Essays: Scientific, Political, & Speculative, Vol. I One might not look for any kind of physical phenomenon which was not due to the presence and activity of some heterogeneity. The Machinery of the Universe Mechanical Conceptions of Physical Phenomena What of that heterogeneity for which New York is famous, or infamous? Imaginary Interviews I reach the same result—heterogeneity of the secondary masses immediately resulting from the atoms—purely from an à priori consideration of their general design—Relation. Eureka: A Prose Poem The fact that the material foundation annuls itself and establishes for itself a realm in the clouds can only be explained from the heterogeneity and self-contradiction of the material foundation. Feuerbach: The roots of the socialist philosophy When, at a later period, there arose salts and other compounds of similar degrees of complexity, there was again an increase of heterogeneity, alike in the aggregate and in its members. Essays: Scientific, Political, & Speculative, Vol. I Perfect knowledge implies the peace of death, implies the state of being one—our pleasures are derived from action, from differences, from heterogeneity. The Wonder No abstract conception can be developed, according to him, until the outward experiences have reached a certain degree of heterogeneity, definiteness, coherence, and so forth. The Will to Believe : and Other Essays in Popular Philosophy I have spoken of a subtle influence which we know to be ever in attendance upon matter, although becoming manifest only through matter’s heterogeneity. Eureka: A Prose Poem Vital changes, both visceral and cerebral, also differ from other changes in their heterogeneity; neither the simultaneous nor the serial acts of digestion or of ratiocination are at all alike. The World's Greatest Books — Volume 14 — Philosophy and Economics To these illustrations of growing heterogeneity, which, though deduced from known physical laws, may be regarded as more or less hypothetical, Geology adds an extensive series that have been inductively established. Essays: Scientific, Political, & Speculative, Vol. I However, the stock was grown in thoroughly mixed soil in a coldframe and differences in performance of seedlings could hardly be attributed to soil heterogeneity. Northern Nut Growers Association Report of the Proceedings at the Thirty-Eighth Annual Meeting Guelph, Ontario, September 3, 4, 5, 1947 But—infinite heterogeneity—or débris from many different kinds of aerial cargoes—there have been red rains that have been colored by neither sand nor animal matter. The Book of the Damned Through the aid—by the means—through the agency of Matter, and by dint of its heterogeneity—is this Ether manifested—is Spirit individualized. Eureka: A Prose Poem Development, or Increase of Structure In each of the organic sub-kingdoms the change from an incoherent, indefinite homogeneity to a coherent definite heterogeneity is illustrated in a quadruple way. The World's Greatest Books — Volume 14 — Philosophy and Economics Thus, between our existing Earth, the phenomena of whose crust neither geographers, geologists, mineralogists, nor meteorologists have yet enumerated, and the molten globe out of which it was evolved, the contrast in heterogeneity is extreme. Essays: Scientific, Political, & Speculative, Vol. I A baby or a barbarian may delight in loud heterogeneity and vivid confusion, but extravagance of sensation does not constitute an æsthetic experience. Human Traits and their Social Significance The physicists have more or less consciously perceived this, and, not being able to overcome by a frontal attack the difficulty created by the heterogeneity of our sensations, they have turned its flank. The Mind and the Brain Being the Authorised Translation of L'Âme et le Corps Any common experiment shows us how readily a crust of the character suggested, is separated, through heterogeneity, from the interior mass. Eureka: A Prose Poem The obstacles to be overcome—native conservatism, intercantonal jealousy, and ecclesiastical heterogeneity—were tremendous. The Governments of Europe Thus the influences which determine this division of labour grow stronger in both ways; and the incipient heterogeneity is, on the average of cases, likely to become permanent for that generation if no longer. Essays: Scientific, Political, & Speculative, Vol. I The two former insure the heterogeneity, while "segregation" brings about the definiteness and coherence, and "equilibration" arrests the process, and determines when dissolutive changes shall begin. Memories and Studies This principle bears the name of the axiom of heterogeneity, or the principle of psycho-physical dualism. The Mind and the Brain Being the Authorised Translation of L'Âme et le Corps While eugenic strength in a state is promoted by variety, too great a heterogeneity offers serious social difficulties. Applied Eugenics It cannot be repeated too often that it is not sameness of function, but heterogeneity of function, that unity requires. The Continental Monthly, Vol. 5, No. 3, March, 1864 Devoted to Literature and National Policy Once more, this double change in the extent and in the elevation of the lands, involved yet another species of heterogeneity—that of coast-line. Essays: Scientific, Political, & Speculative, Vol. I In the first edition of "First Principles" an evolutive change in anything was described as the passage of it from a state of indefinite incoherent homogeneity to a definite coherent heterogeneity. Memories and Studies On looking closely into it, we shall perceive that the principle of heterogeneity does not contain the consequences it is sought to ascribe to it. The Mind and the Brain Being the Authorised Translation of L'Âme et le Corps Herbert Spencer calls it the dissolution of definite coherent heterogeneity into indefinite incoherent homogeneity. Creative Chemistry Descriptive of Recent Achievements in the Chemical Industries An analysis of the advertisements of the Argus is almost equally interesting as showing the heterogeneity of the wants of the community. Town Life in Australia We merely learn that some kind of heterogeneity is inevitable; but as yet there is nothing to tell us what kind. Essays: Scientific, Political, & Speculative, Vol. I Once more, this double change in the extent and in the elevation of the lands, involved yet another species of heterogeneity, that of coast-line. Essays on Education and Kindred Subjects Everyman's Library The criticisms which have been directed against materialism are all, or nearly all, variations of the principle of heterogeneity. The Mind and the Brain Being the Authorised Translation of L'Âme et le Corps To the two preceding causes of the formations of castes, the ethnological cause, now very weak, and the professional, which is still very strong, are added political office, and the heterogeneity of religious beliefs. The Great Events by Famous Historians, Volume 01 The principal shops are noticeable for their size and the heterogeneity of their contents. Town Life in Australia The first is that since the cooling of the Earth reached an advanced stage, the components of its crust have been ever increasing in heterogeneity. Essays: Scientific, Political, & Speculative, Vol. I To these illustrations of growing heterogeneity, which, though deduced from the known laws of matter, may be regarded as more or less hypothetical, Geology adds an extensive series that have been inductively established. Essays on Education and Kindred Subjects Everyman's Library These three quotations show very conclusively that their authors thought they could establish the heterogeneity of the two phenomena by opposing matter to sensation. The Mind and the Brain Being the Authorised Translation of L'Âme et le Corps There are also the issues of labour heterogeneity and optimal taxation that we have encountered in discussing the Simple View, but that have not had sufficient attention. Definition & Reality in the General Theory of Political Economy These Irish are less impertinent than the colonials; but if you do get hold of a well trained colonial, she is worth her weight in gold on account of her heterogeneity. Town Life in Australia The nature of the case thus forbids us to expect to find the Chinese myths exhibiting the advanced state and brilliant heterogeneity of those which have become part of the world’s permanent literature. Myths and Legends of China Thus the influences that determine this division of labour grow stronger in both ways; and the incipient heterogeneity is, on the average of cases, likely to become permanent for that generation, if no longer. Essays on Education and Kindred Subjects Everyman's Library It seems that all materialists have acknowledged that here is the vulnerable point in their theory, for it is the principle of heterogeneity which they have especially combated. The Mind and the Brain Being the Authorised Translation of L'Âme et le Corps The group only exists if we acknowledge heterogeneity. Definition & Reality in the General Theory of Political Economy Spencer invented the notion of a primordial homogeneity, from which it is impossible to conceive how any heterogeneity could originate. Tragic Sense Of Life Nature and Law compel it: whose direction now is towards grand centripetalism, where before they had ordained heterogeneity and the scattering and aloofness of peoples. The Crest-Wave of Evolution A Course of Lectures in History, Given to the Graduates' Class in the Raja-Yoga College, Point Loma, in the College-Year 1918-19 Moreover, through the complications of effects flowing from single causes, we here find, what we before inferred, not only an increase of general heterogeneity, but also of special heterogeneity. Essays on Education and Kindred Subjects Everyman's Library That which philosophers criticised in materialism was the misunderstanding of the principle of heterogeneity. The Mind and the Brain Being the Authorised Translation of L'Âme et le Corps We will use heterogeneity mainly to explain the effect of the minimum wage. Definition & Reality in the General Theory of Political Economy For how, without any action from without, can any heterogeneity emerge from perfect and absolute homogeneity? Tragic Sense Of Life One result that a miscellany of racial heterogeneities was washed up into the peninsular and island extremities of the continent. The Crest-Wave of Evolution A Course of Lectures in History, Given to the Graduates' Class in the Raja-Yoga College, Point Loma, in the College-Year 1918-19 The faint scent of iodoform that he now gave off was a heterogeneity, like a whiff of brandy on a parson. V. V.'s Eyes Antonyms: agree, concur. difference, n. dissimilarity, unlikeness, distinction, variation, contrast, discrepancy, discrimination, disparity, diversity, dissimilitude, incompatibility, inequality, heterogeneity, variety; dissension, variance. Putnam's Word Book With heterogeneity, the unemployment that is relevant for a submarket will have effects on the evolution of the wage in that submarket. Definition & Reality in the General Theory of Political Economy Science seeks to reduce the multiplicity and heterogeneity of facts as they occur to these simple formulas of law. Heart of Man He had to deal, then, with a heterogeneity as pronounced as that which confronted Napoleon; but he was not of the stuff for which you prepare Waterloos. The Crest-Wave of Evolution A Course of Lectures in History, Given to the Graduates' Class in the Raja-Yoga College, Point Loma, in the College-Year 1918-19 In any case philosophy retains as an inalienable possession the negative conclusion, that, in view of the heterogeneity of consciousness and motion, the inner life is not reducible to material phenomena. History of Modern Philosophy From Nicolas of Cusa to the Present Time The conception of a pure Aryan, Indo-European race has been abandoned in scientific circles, and the secret of the progress of Europe has been found in racial heterogeneity, rather than in racial purity. The Wife of his Youth and Other Stories of the Color Line, and Selected Essays Their formal analysis uses homogeneous labour and proportional taxes, though some of their statements allow for an interpretation of heterogeneity and nonproportionality. Definition & Reality in the General Theory of Political Economy The psychological basis of the twice-born character seems to be a certain discordancy or heterogeneity in the native temperament of the subject, an incompletely unified moral and intellectual constitution. Varieties of Religious Experience, a Study in Human Nature No one dreamed that he would treat the world other than as such a heterogeneity. The Crest-Wave of Evolution A Course of Lectures in History, Given to the Graduates' Class in the Raja-Yoga College, Point Loma, in the College-Year 1918-19 "Talking of Herbert Spencer," he began, "do you really find no logical difficulty in regarding Nature as a process of involution, passing from definite coherent homogeneity to indefinite incoherent heterogeneity?" Sylvie and Bruno To him the world is truly a universe, not a heterogeneity of unrelated things. The Poet's Poet : essays on the character and mission of the poet as interpreted in English verse of the last one hundred and fifty years Mere heterogeneity, together with gravitation, is sufficient to explain all the apparently discordant laws of molecular action. Heart and Science A Story of the Present Time All writers about that temperament make the inner heterogeneity prominent in their descriptions. Varieties of Religious Experience, a Study in Human Nature —Now Math—he was a famous wizard of old—means 'sort,' 'kind'; and so implies such ideas as 'differentiation,' 'heterogeneity.' The Crest-Wave of Evolution A Course of Lectures in History, Given to the Graduates' Class in the Raja-Yoga College, Point Loma, in the College-Year 1918-19 Matter moves by its own energy, by a necessary consequence of its heterogeneity. Good Sense Considerations on the aspect of a country are independent of those which indicate the nature of the soil, the heterogeneity of matter, the superposition of rocks and the direction and inclination of strata. Personal Narrative of Travels to the Equinoctial Regions of America, During the Year 1799-1804 — Volume 3 The truth that all organic development is a change from a state of homogeneity to a state of heterogeneity is regarded by Spencer as the organizing principle of his subsequent beliefs. Beacon Lights of History, Volume 14 The New Era; A Supplementary Volume, by Recent Writers, as Set Forth in the Preface and Table of Contents This amount of inconsistency will only count as amiable weakness; but a stronger degree of heterogeneity may make havoc of the subject's life. Varieties of Religious Experience, a Study in Human Nature Such reckless heterogeneity as this is impossible with Froebel's educational materials, for even if they are given to the child without a single word, they carry something of their own logic with them. Children's Rights A book of nursery logic La duree appears as a "wholly qualitative multiplicity, an absolute heterogeneity of elements which pass over into one another." Bergson and His Philosophy The condition that has contributed to its great width is the heterogeneity of the different formations—some hard and some soft. Time and Change The primordial cell in differentiating out of homogeneity into heterogeneity developed different qualities in different beings, and of the organs integrated from the heterogeneous elements each has its use and many are essential to life. The Inhumanity of Socialism Unable to differentiate themselves from the hated Serbs racially - they appealed to religious heterogeneity. Terrorists and Freedom Fighters "A Truth-Seeker," he gravely explained, "is one who believes in—eh—in a progress from an indefinite, incoherent homogeneity to a definite, coherent heterogeneity." Tillie, a Mennonite Maid; a Story of the Pennsylvania Dutch The war with Croatia and more so in Bosnia was a direct result of ethnic heterogeneity. After the Rain : how the West lost the East Already, too, it presents an increased heterogeneity—especially in the distribution of its convolutions. Physics and Politics, or, Thoughts on the application of the principles of "natural selection" and "inheritance" to political society I believe, however, that the justification of this apparent heterogeneity, and the basis for explanation, is given in the reduction of all elements to their lowest term,—as objects for the expenditure of attention. The Psychology of Beauty It stood for the American factory town; for municipal indifference and social neglect, for heterogeneity in population, for the tinder pile awaiting the incendiary match. The Armies of Labor A chronicle of the organized wage-earners It introduces expectations of cultural homogeneity in a context that thrives on heterogeneity. The Civilization of Illiteracy The nationalist school depended on denial and repression of the existence of heterogeneity and of national minorities. After the Rain : how the West lost the East Polynesians, wide geographical range of; difference of stature among the; crosses of; variability of; heterogeneity of the; aversion of, to hairs on the face. The Descent of Man All life, whether organic or inorganic, consists, as we know, in a change from a state of simple homogeneity to one of complex heterogeneity. The Soul of the Far East At bottom Mr Bergson is bringing forward the necessity, in the case before us, of substituting a new notion of continuous qualitative heterogeneity for the old notion of numerical and spatial continuity. A New Philosophy: Henri Bergson The other, of the adopted country, is focused upon needs that effect the transition to the civilization of illiteracy- heterogeneity, horizontality, decentralism, tradition as choice, but not way of life. The Civilization of Illiteracy The heterogeneity of the world, its intrinsic relativity, and its dynamics of change mark religious practical experiences in ways not dissimilar to those of scientific, artistic, political, educational, moral, and many other experiences. The Civilization of Illiteracy The pragmatic framework of our new age corresponds to the need to acknowledge differences and derive from heterogeneity new sources of creativity. The Civilization of Illiteracy The multiplicity of food-related experiences in our time is representative of segmentation and heterogeneity in the civilization of illiteracy. The Civilization of Illiteracy But in biology and psychology quite different characteristics become essential; age and memory, heterogeneity of musical phases, irreversible rhythm "which cannot be lengthened or shortened at will." A New Philosophy: Henri Bergson Cognitive skills are required in the new pragmatic context together with meta-cognitive skills: how to control one's own learning, for example, in a world of change, variety, distributed effort, mediated work, interconnection, and heterogeneity. The Civilization of Illiteracy The underlying structure of the civilization of illiteracy supports a pragmatics of heterogeneity, distributed tasks, and networking. The Civilization of Illiteracy |
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