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单词 haemoglobin
例句 haemoglobin
David Williams, of the Boston Children’s Cancer and Blood Disorders Center, is using a slightly different technique to boost foetal haemoglobin but also hopes to begin trials next year. Gene therapy offers hope for treatment of sickle cell anaemia 2016-10-01T04:00:00Z
But almost immediately they saw something astonishing: each of the four protein chains that makes up haemoglobin looked like myoglobin. Myoglobin: turd of the century? 2013-04-19T06:29:00Z
In 1959 Max Perutz, whose methodological work had been crucial to Kendrew's success, solved the structure of haemoglobin, only the second protein molecule to be analysed by X-ray crystallography. Myoglobin: turd of the century? 2013-04-19T06:29:00Z
The mutated haemoglobin undergoes a change in shape and blocks veins. Gene therapy offers hope for treatment of sickle cell anaemia 2016-10-01T04:00:00Z
Give away a pint and your plasma will regenerate within 24 hours and your haemoglobin within weeks. Blood tales: the magic liquid that keeps us alive 2018-10-20T04:00:00Z
What made this observation all the more remarkable is that Kendrew's myoglobin had been purified and crystallised from the meat of a sperm whale, while Perutz's haemoglobin came from a horse. Myoglobin: turd of the century? 2013-04-19T06:29:00Z
Type 2 diabetes can be confirmed by a blood test to measure average levels of haemoglobin A1c in the last three months. Millions unnecessarily labelled pre-diabetic, health experts say 2014-07-15T04:00:00Z
The prospect of boosted foetal haemoglobin levels in patients was helped when it was found that a gene called BCL11A acts as a suppressor of foetal haemoglobin production. Gene therapy offers hope for treatment of sickle cell anaemia 2016-10-01T04:00:00Z
It might make sense on simple logic because this is what it does in plants, and the pigment's similarities to haemoglobin. What is chlorophyll water? 2022-12-05T05:00:00Z
But in some individuals foetal haemoglobin production is not turned off at birth. Gene therapy offers hope for treatment of sickle cell anaemia 2016-10-01T04:00:00Z
“What we aim to do is to stop it doing this. We want to suppress the suppressor and allow foetal haemoglobin to continue to be made in the body.” Gene therapy offers hope for treatment of sickle cell anaemia 2016-10-01T04:00:00Z
And crucial to this task was the discovery by Orkin and colleagues that a small piece of the BCL11A gene, called the enhancer, controls foetal haemoglobin expression. Gene therapy offers hope for treatment of sickle cell anaemia 2016-10-01T04:00:00Z
“When you knock BCL11A down, you simultaneously increase foetal haemoglobin and repress sickling haemoglobin, which is why we think this is the best approach,” said Williams. Gene therapy offers hope for treatment of sickle cell anaemia 2016-10-01T04:00:00Z
People with beta thalassaemia do not produce enough haemoglobin, which is used by red blood cells to carry oxygen around the body. Casgevy: UK approves gene-editing drug for blood disorders 2023-11-16T05:00:00Z
The drug increases both the number of red blood cells and the amount of haemoglobin - a protein that carries oxygen in your body - found in those cells. Why has Halep been given four-year doping ban? 2023-09-15T04:00:00Z
"So the common symptoms are for people to go to their GP saying they feel a bit lethargic, they have their blood tested, their haemoglobin is low and that is quite a common presentation." NHS at 75: Robotic arms used in delicate colon surgery 2023-07-05T04:00:00Z
Studies have shown that male puberty results in increased muscle mass, bone density, changes to the shape of the skeleton, and the haemoglobin levels, all of which are significant contributors to performance. World Athletics proposes new transgender rules 2023-01-23T05:00:00Z
Red blood cells are normally round and squishy, but mutated haemoglobin can make them rigid and take on their characteristic sickle shape. Sickle cell: ‘The revolutionary gene-editing treatment that gave me new life’ 2022-02-19T05:00:00Z
This is a revolutionary advance for two inherited blood conditions, both triggered by errors in the gene for haemoglobin. Casgevy: UK approves gene-editing drug for blood disorders 2023-11-16T05:00:00Z
"Proteins are vitally important - for organs like our brain and heart, the antibodies in our immune system, the haemoglobin that carries oxygen in our blood, and to keep our muscles and bones healthy," she says. The appetite for protein bars gives much to chew on 2022-02-16T05:00:00Z
Blood-forming stem cells from her bone marrow were collected and treated outside her body to alter a gene involved in haemoglobin production, before being transfused back. After the Nobel, what next for Crispr gene-editing therapies? 2021-02-21T05:00:00Z
Abhijit suffered from thalassaemia major, a disorder where his haemoglobin count was dangerously low and he required frequent blood transfusions. India's first 'saviour sibling' cures brother of fatal illness 2020-10-26T04:00:00Z
In the trial, scientists would genetically engineer his body so he no longer produced that tainted haemoglobin. Sickle cell: ‘The revolutionary gene-editing treatment that gave me new life’ 2022-02-19T05:00:00Z
The modified cells are infused back, allowing the body to start producing functioning haemoglobin. Casgevy: UK approves gene-editing drug for blood disorders 2023-11-16T05:00:00Z
Doctors measure what they call oxygen saturation - the percentage of haemoglobin molecules in the blood that are carrying oxygen. 'Baffling' observations from the front line 2020-05-23T04:00:00Z
Writing in Nature, Pillai et al.4 reconstruct the stepwise evolution of haemoglobin from precursors that existed more than 400 million years ago. Extinct proteins resurrected to reconstruct the evolution of vertebrate haemoglobin 2020-05-19T04:00:00Z
Dr Amit Raithatha, from London, suffers from thalassaemia, a rare blood disorder that means he produces very little haemoglobin, which is used by blood cells to carry oxygen around the body. Blood donations needed after 15% drop, says NHS 2020-03-22T04:00:00Z
It is caused by a genetic mutation that leads to the body making abnormal haemoglobin. Sickle cell: ‘The revolutionary gene-editing treatment that gave me new life’ 2022-02-19T05:00:00Z
In trials, it has been "found to restore healthy haemoglobin production in the majority of participants with sickle-cell disease and transfusion-dependent beta thalassaemia, relieving the symptoms of disease", he said. Casgevy: UK approves gene-editing drug for blood disorders 2023-11-16T05:00:00Z
At MIT, he created a class of biomimetic molecule that reversibly binds oxygen when complexed with iron, just as haemoglobin does in the blood, and formulated his rules for ring formation. Jack Baldwin (1938–2020) 2020-02-06T05:00:00Z
Figure 1 | Key steps in the evolution of the tetrameric haemoglobin protein. Extinct proteins resurrected to reconstruct the evolution of vertebrate haemoglobin 2020-05-19T04:00:00Z
The haemoglobin A1C test, which monitors how well a person is managing the condition, would not be developed by researchers at the Joslin Diabetes Center in Boston, Massachusetts, for three more years. How I find career motivation in my father’s diabetes 2020-01-26T05:00:00Z
When we are still in the womb, our bodies use a different type of haemoglobin called foetal haemoglobin. Sickle cell: ‘The revolutionary gene-editing treatment that gave me new life’ 2022-02-19T05:00:00Z
Sickle cell anaemia is a genetic disorder marked by misshapen haemoglobin.Credit: Quest to use CRISPR against disease gains ground 2020-01-05T05:00:00Z
Roughly a quarter of these will be snapped up by the hungry iron atoms in the haemoglobin of your red blood cells. Deep Breather 2019-12-22T05:00:00Z
The authors showed that the protein AncMH, the last common ancestor of haemoglobin and the related protein myoglobin, existed as a monomer. Extinct proteins resurrected to reconstruct the evolution of vertebrate haemoglobin 2020-05-19T04:00:00Z
On 25 November, the US Food and Drug Administration approved a drug for sickle-cell that aims to reduce clumping between haemoglobin molecules. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z
This grabs hold of oxygen more tightly than adult haemoglobin and is essential for a developing baby to take oxygen out of its mother's bloodstream. Sickle cell: ‘The revolutionary gene-editing treatment that gave me new life’ 2022-02-19T05:00:00Z
Made by Global Blood Therapeutics in South San Francisco, California, it reduces the interactions between mutated haemoglobin proteins that lead to the sickled blood cells characteristic of the condition. Expensive treatments for genetic disorders are arriving. But who should foot the bill? 2019-12-03T05:00:00Z
One protein degrades haem, a component of the blood protein haemoglobin. Only vaccines can eradicate parasitic worms 2019-11-26T05:00:00Z
The earliest protein — a common ancestor of haemoglobin and the monomeric globin protein myoglobin, named AncMH by the authors — exists only as a monomer. Extinct proteins resurrected to reconstruct the evolution of vertebrate haemoglobin 2020-05-19T04:00:00Z
Others are introducing modified copies of the genes that encode fetal haemoglobin, a form of the protein that is produced in the developing fetus but usually shuts off soon after birth. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z
After we're born, a genetic switch is flipped and we start making adult haemoglobin. Sickle cell: ‘The revolutionary gene-editing treatment that gave me new life’ 2022-02-19T05:00:00Z
Ambient light passes easily through human skin and tissue, but is absorbed by the haemoglobin in red blood cells. Wearable graphene sensors use ambient light to monitor health 2019-11-17T05:00:00Z
The other protein prevents hookworms from breaking down haemoglobin for consumption. Only vaccines can eradicate parasitic worms 2019-11-26T05:00:00Z
These features are shared by all living jawed vertebrates, but are absent or achieved in a different way in jawless vertebrates, whose haemoglobin proteins are of more ancient origin. Extinct proteins resurrected to reconstruct the evolution of vertebrate haemoglobin 2020-05-19T04:00:00Z
A third approach seeks to block a mechanism that switches off production of fetal haemoglobin after birth. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z
Crucially, it's only the adult form of haemoglobin that is affected by sickle cell disease. Sickle cell: ‘The revolutionary gene-editing treatment that gave me new life’ 2022-02-19T05:00:00Z
Light at certain wavelengths passes easily through human skin and adjacent tissue, but is absorbed strongly by blood7 — more specifically, it is absorbed by haemoglobin, the molecule that transports oxygen in red blood cells. Wearable graphene sensors use ambient light to monitor health 2019-11-17T05:00:00Z
Perutz’s group was using X-ray crystallography to unravel the structures of the proteins haemoglobin and myoglobin. The structure of DNA 2019-10-08T04:00:00Z
However, haemoglobin is well suited for this type of study for several reasons. Extinct proteins resurrected to reconstruct the evolution of vertebrate haemoglobin 2020-05-19T04:00:00Z
Now, Malik is leading a trial that introduces stem cells that produce fetal haemoglobin. Gene therapy is facing its biggest challenge yet 2019-12-03T05:00:00Z
The same genetic procedure has been performed on a total of 45 patients with either sickle cell disease or another blood disorder called beta thalassaemia, which is caused by malformed haemoglobin. Sickle cell: ‘The revolutionary gene-editing treatment that gave me new life’ 2022-02-19T05:00:00Z
The parasites attach to your red blood cells, penetrate the outer defences, and feast on the haemoglobin within. Man v mosquito: what to do about our biggest killer 2019-09-20T04:00:00Z
Similarly, the team found that a variant in the haemoglobin gene - a gene known for its role in sickle cell anaemia - is associated with a greater amount of blood glucose attached to haemoglobin in African-Americans. Is routine genetic profiling coming closer? 2019-07-29T04:00:00Z
It will be interesting to probe the evolutionary origins of the regulation of haemoglobin oxygen binding by other effectors, such as carbon dioxide or physiologically relevant organic phosphates including ATP and 2,3-bisphosphoglycerate. Extinct proteins resurrected to reconstruct the evolution of vertebrate haemoglobin 2020-05-19T04:00:00Z
He went to hospital and had blood samples taken, which showed his haemoglobin level was dangerously low and he did not have enough platelets. 'I call my stem cell donor my sister' 2019-06-08T04:00:00Z
Testosterone increases muscle mass, strength and haemoglobin, which affects endurance. Physicians group calls on members to reject IAAF regulations 2019-05-03T04:00:00Z
Testosterone is a hormone that increases muscle mass, strength and haemoglobin - which affects endurance. Semenya decision to be announced by CAS on Wednesday 2019-04-29T04:00:00Z
Haem is a key component of the haemoglobin in red blood cells that transport oxygen around the body. 'New class' of medicine reverses disease 2019-04-13T04:00:00Z
This remains an open question in the evolution of the genes that encode haemoglobin’s subunits. Extinct proteins resurrected to reconstruct the evolution of vertebrate haemoglobin 2020-05-19T04:00:00Z
The disease is caused by mutations in the β-globin gene, which encodes a subunit of haemoglobin, the oxygen-carrying protein found in red blood cells. Prenatal gene therapy offers the earliest possible cure 2018-12-11T05:00:00Z
The approach is promising because just a single gene needs correcting: the one for the β-globin subunit of haemoglobin, the body’s oxygen ferry. Gene therapy targets sickle-cell disease 2018-12-11T05:00:00Z
The year after, he did theoretical studies on the kinetics of oxygen uptake by the blood pigment haemoglobin with physiologist F. J. W. Roughton. Aaron Klug (1926-2018) 2018-12-11T05:00:00Z
His sentence, which was based on evidence that suggested abnormal levels of haemoglobin in the players’ blood, was overturned on appeal a year later. Is the World Cup really free from doping? 2018-07-06T04:00:00Z
Testosterone is a hormone that increases muscle mass, strength and haemoglobin, which affects endurance. South Africa's Semenya to challenge IAAF 2018-06-18T04:00:00Z
In β-thalassaemia, haemoglobin is less able to carry oxygen, leading to fatigue, growth stunting and damage to organs. Prenatal gene therapy offers the earliest possible cure 2018-12-11T05:00:00Z
He said: "A major question hanging over this approach, which is hugely expensive, is whether this procedure will ever become clinically possible in developing countries, where the majority of these disorders of haemoglobin occur." 'Encouraging' therapy for blood disorder 2018-04-18T04:00:00Z
Clinical trials may soon test whether gene editing can cure a group of debilitating haemoglobin disorders. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z
For one thing, they are not in hospital and are living close to normal lives — regular transfusions notwithstanding — yet they are assessed using the same haemoglobin thresholds as people in intensive care, McQuilten says. Transfusion: Too much of a good thing : Nature : Nature Research 2017-09-26T04:00:00Z
In A Study in Scarlet, for instance, Holmes exclaims, “I have found a reagent which is precipitated by haemoglobin, and by nothing else.” Fiction: The science in Sherlock Holmes : Nature : Nature Research 2017-09-19T04:00:00Z
The component estimates the amount of oxygenated haemoglobin in blood. Fitbit Ionic smartwatch introduces blood oxygen sensor - BBC News 2017-08-29T04:00:00Z
My heart was beating in an irregular rhythm, which I am pretty sure has been the case for years, and I had a really low haemoglobin count. Roxane Gay: ‘My body is a cage of my own making’ 2017-07-01T04:00:00Z
The second encourages the production of fetal haemoglobin, the form of haemoglobin used by humans in the womb. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z
The death rate from all causes within 30 days of patients' admission to intensive care was similar regardless of whether the decision to transfuse blood was implemented at the higher or lower haemoglobin level. Transfusion: Too much of a good thing : Nature : Nature Research 2017-09-26T04:00:00Z
The plant-based ingredients they settled on were wheat and potato proteins, natural flavourings and coconut oil, with the key addition of haem — the iron-containing group that is abundant in animal tissue as haemoglobin or myoglobin. Sustainability: A meaty issue : Nature : Nature Research 2017-04-25T04:00:00Z
Sickle cell is caused by a typo in the instructions for making the protein haemoglobin, which is densely packed into red blood cells. World-first therapy reverses sickle cell in teenage boy - BBC News 2017-03-02T05:00:00Z
The orthopaedic surgeon couldn’t operate because of my low haemoglobin, so I got my first blood transfusion. Roxane Gay: ‘My body is a cage of my own making’ 2017-07-01T04:00:00Z
It turns out that people with sickle-cell disease who are not badly affected by symptoms have genetic variations that enable them to produce fetal haemoglobin into adulthood. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z
But a restrictive threshold and a lower level of haemoglobin may not be suitable for all patients. Transfusion: Too much of a good thing : Nature : Nature Research 2017-09-26T04:00:00Z
When DNA-cloning technologies became available, Smithies studied some of the human genes for haptoglobin and haemoglobin. Oliver Smithies (1925-2017) : Nature : Nature Research 2017-02-07T05:00:00Z
In mice, only up to 5% of the transplanted, edited cells produced the normal form of haemoglobin. CRISPR deployed to combat sickle-cell anaemia 2016-10-11T04:00:00Z
Monitoring haemoglobin therefore monitors how much oxygen brain cells are using, which in turn is a proxy for how hard they are working. Computer says: oops 2016-07-14T04:00:00Z
Red blood cells produced from the edited haematopoietic stem cells of patients with sickle-cell disease produced 25% more fetal haemoglobin than unedited cells, and the edited cells successfully engrafted in mice. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z
But he objects to transfusions being given simply to raise a patient's haemoglobin level. Transfusion: Too much of a good thing : Nature : Nature Research 2017-09-26T04:00:00Z
This group is blasting X-ray pulses at haemoglobin — the oxygen-carrying protein in red blood cells — in the hope of working out exactly how oxygen molecules bind to its iron-atom core. 24 hours at the X-ray factory 2016-03-28T04:00:00Z
It is caused by a mutation that affects the shape of the oxygen-carrying protein haemoglobin in red blood cells. CRISPR deployed to combat sickle-cell anaemia 2016-10-11T04:00:00Z
For instance, red meat is rich in iron derived from haemoglobin, which is more easily absorbed than the non-haem form found in beans and leafy greens. Brain food: Clever eating : Nature : Nature Publishing Group 2016-03-01T05:00:00Z
Most people, however, stop making fetal haemoglobin after they are born, and instead begin to produce haemoglobin containing β-globin. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z
For instance, Ceracor will debut a sensor that measures the level of haemoglobin in the blood, which it says athletes can use to boost their endurance. CES 2016: Preview of the Las Vegas tech showcase - BBC News 2016-01-01T05:00:00Z
Red meat is a darker colour than white meat and includes beef, lamb and pork because of higher levels of proteins that bind to oxygen, haemoglobin and myoglobin in blood and muscle. What is processed meat? - BBC News 2015-10-26T04:00:00Z
Despite taking EPO for seven weeks, seeing steady rises in my haemoglobin and haematocrit counts, and gaining a significant performance benefit, I was clean. How I became a drug cheat athlete to test the system - BBC News 2015-06-04T04:00:00Z
But the hospital's electronic medical records revealed that 84% of patients in one unit and 92% in the other received transfusions before their haemoglobin levels fell that low. Evidence-based medicine: Save blood, save lives 2015-03-30T04:00:00Z
Most people with haemoglobin disorders, though, live in the developing world and will not be able to pay, says Sankaran. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z
When near-infrared light is transmitted through your finger, part of it gets absorbed by the haemoglobin in your veins. The new rise of biometric banking 2015-03-19T04:00:00Z
A phase I trial in patients with β-thalassaemia — a genetic blood disorder caused by insufficient haemoglobin production — is scheduled to begin this year. Don’t edit the human germ line 2015-03-11T04:00:00Z
With support from the Jamaican ministries of health and education, we offered free, voluntary testing for haemoglobin genotype to students mostly aged 15–19 over a period of six years. Q&A: Healthy progress : Nature : Nature Publishing Group 2014-11-11T05:00:00Z
All six studies revealed that patients fare just as well, and sometimes better, when doctors use lower haemoglobin thresholds. Evidence-based medicine: Save blood, save lives 2015-03-30T04:00:00Z
They hope to cure sickle-cell disease while patients are still children, by editing the haemoglobin genes in stem cells taken from the children's blood-producing bone marrow, which can then be transplanted back. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z
This results in the production of abnormal haemoglobin proteins that cause the red blood cells that house them to twist and become sickle shaped. Gene therapy: Editorial control : Nature : Nature Publishing Group 2014-11-11T05:00:00Z
The disease-causing mutation occurs in a gene responsible for the production of haemoglobin, the protein in red blood cells that carries oxygen to tissues throughout the body. Epidemiology: A moving target : Nature : Nature Publishing Group 2014-11-11T05:00:00Z
What begins as one small genetic alteration — a single faulty nucleotide in a haemoglobin gene — ends in a cascade of damage. Drug development: A complicated path : Nature : Nature Publishing Group 2014-11-11T05:00:00Z
Doctors typically decide whether to do a transfusion by measuring a patient's level of haemoglobin, the protein inside red blood cells that binds to oxygen. Evidence-based medicine: Save blood, save lives 2015-03-30T04:00:00Z
Made from a combination of subunits that does not include β-globin, it binds to oxygen more strongly than does adult haemoglobin, helping the fetus to take up oxygen from the mother's blood. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z
The researchers correct the haemoglobin gene defect in vitro using gene editing, then differentiate the repaired iPS cells into blood stem cells. Gene therapy: Editorial control : Nature : Nature Publishing Group 2014-11-11T05:00:00Z
The gene responsible for sickle haemoglobin confers increased resistance to the malaria parasite when inherited from only one parent. Epidemiology: A moving target : Nature : Nature Publishing Group 2014-11-11T05:00:00Z
Rather than treating the acute pain of vaso-occlusive crises, hydroxycarbamide prevents long-term consequences of the disease primarily by stimulating production of the fetal form of haemoglobin. Drug development: A complicated path : Nature : Nature Publishing Group 2014-11-11T05:00:00Z
Historically, doctors would consider a transfusion when a patient's haemoglobin fell below 10 g dL−1, a trigger that was proposed in a 1942 paper3. Evidence-based medicine: Save blood, save lives 2015-03-30T04:00:00Z
On the other side of the United States, two CRISPR-focused start-up companies are taking what they hope will be a less risky approach — interfering with genes that regulate fetal haemoglobin. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z
Work by scientists at Lund University built upon an earlier study published in the journal Plant & Cell Physiology that found haemoglobin had an important role in plant development. Plant protein could be used in blood 2014-11-05T05:00:00Z
Light transmitted through the finger is partially absorbed by haemoglobin passing through the veins, enabling the unit to authenticate the user's vein pattern. Bank customers to sign in with veins 2014-09-04T04:00:00Z
So researchers are investigating other drugs that stimulate fetal haemoglobin. Drug development: A complicated path : Nature : Nature Publishing Group 2014-11-11T05:00:00Z
In the year before the computerized alerts began, just over half of transfusions were done on patients with haemoglobin levels of greater than 8 g dL−1. Evidence-based medicine: Save blood, save lives 2015-03-30T04:00:00Z
Meanwhile, Editas Medicine presented results from their work on fetal haemoglobin genes at the American Society of Gene and Cell Therapy annual meeting in May. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z
She said her work raised two possibilities - potentially adapting plant haemoglobin for use in humans and looking at using plants as a way of producing human haemoglobin. Plant protein could be used in blood 2014-11-05T05:00:00Z
When P. falciparum invades red blood cells and feeds on their contents, it breaks down haemoglobin into amino acids and haem, a chemical compound that contains iron. Quick test for malaria shows promise 2014-08-30T04:00:00Z
In each case, says Pace, “our goal is to reactivate the fetal haemoglobin gene, or to keep it active, if you treat a very young child”. Drug development: A complicated path : Nature : Nature Publishing Group 2014-11-11T05:00:00Z
Red meat looks darker than white meat like poultry because of higher levels of haemoglobin and myoglobin, the iron and oxygen-binding proteins you find in blood and muscle. How safe is eating meat? 2014-08-17T04:00:00Z
Specialists said he had suffered significant blood loss and his haemoglobin had fallen to "an extremely life-threatening level". Prisoner blood decision 'right' 2014-05-06T16:53:37Z
But he said the idea of using the plant protein to substitute for human haemoglobin was speculative and would be a long-term prospect. Plant protein could be used in blood 2014-11-05T05:00:00Z
When Michael Tift, a comparative physiologist at Scripps, analysed blood samples from 24 elephant seals on a California beach, he found high levels of haemoglobin. Elephant Seals Reveal Anti-Inflammatory Secrets of Carbon Monoxide 2014-05-02T16:23:00Z
As haemoglobin strongly absorbs green light, the captured light intensity decreases as the total haemoglobin concentration increases during changes in cerebral blood volume and flow. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z
This functions like haemoglobin in the blood, allowing the whales to store much higher levels of oxygen, and thus breathe less frequently while remaining active. Beaked whale is deep-dive champion 2014-03-26T21:22:58Z
"Since then studies on this vulture revealed a number of features in their haemoglobin and a number of cardio-vascular adaptations that allow breathing in rarefied atmosphere," explains Mr Thomsett. Seven surprising facts about vultures 2014-01-31T01:58:55Z
The plant haemoglobin behaved similarly to a version found in the human brain and had a similar structure, he said. Plant protein could be used in blood 2014-11-05T05:00:00Z
In the 1960s, researchers discovered that mammals produce carbon monoxide when haemoglobin and myoglobin proteins in their cells degrade. Elephant Seals Reveal Anti-Inflammatory Secrets of Carbon Monoxide 2014-05-02T16:23:00Z
Other structures such as myoglobin and haemoglobin were also later recognised with Nobel Prizes. Unsung technique behind key science discoveries 2013-12-18T01:20:48Z
But she said: "Not everyone is going to benefit from it and experience an increase of haemoglobin and improvement in the transport of oxygen." How can an athlete enhance performance legally? 2013-11-23T00:55:16Z
The inmate said he turned a corner eight weeks ago when his haemoglobin levels plummeted, he became anaemic and needed a blood transfusion. Agency backs drugs policy rethink 2012-12-10T08:59:28Z
A recent looked at some of the attempts, past and present, to create artificial blood products, including efforts to develop haemoglobin treatments from E.coli bacteria and from stem cells. New blood 'booster' tested in UK 2012-09-30T23:24:38Z
This substance reacts with iron in blood's haemoglobin to produce a blue-white glow. Covenant signature 'not in blood' 2012-09-27T16:57:07Z
Eradicate money and marketing from the Olympic haemoglobin. Barney Ronay on those empty seats 2012-07-31T14:43:21Z
Once inside the bacterium, the haemoglobin is broken down to release the precious iron that it carries. Pathogens that feed off human blood 2012-05-05T19:15:00.220Z
Alcohol prevents the haemoglobin of the blood from doing its office, which is to supply oxygen and remove carbon dioxid. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z
Simple daily tasks become very hard for someone with MDS, Patricia says She suffers from chronic tiredness and weakness due to extremely low levels of haemoglobin in her blood. 'My son disabled by rare disease' 2012-02-26T01:04:37Z
This is the result of the very considerable destruction of the blood-corpuscles which takes place, the haemoglobin of which is absorbed by the parasites as nutriment. Encyclopaedia Britannica, 11th Edition, Volume 12, Slice 7 "Gyantse" to "Hallel" 2011-12-26T03:00:11.613Z
The tincture of guaiacum is universally used as a test for the presence of blood, or rather of haemoglobin, the red colouring matter of the blood, in urine or other secretions. Encyclopaedia Britannica, 11th Edition, Volume 12, Slice 6 "Groups, Theory of" to "Gwyniad" 2011-12-16T03:00:12.320Z
It’s not quite clear whether the exporters are taking away the haem or some other toxic product, but they are vital for preventing the toxic effects of haemoglobin within the bacteria. Pathogens that feed off human blood 2012-05-05T19:15:00.220Z
The reason is that, besides its well-known role in haemoglobin, the oxygen-transporting molecule in the blood, iron is also involved in many aspects of brain development. Infantile anaemia: Blood simple 2011-11-23T19:48:00Z
In red blood cells containing the aberrant sickle-cell haemoglobin, Lanzer and his team observed that the hijacking of actin filaments by the parasite was hobbled. Sickle-Cell Anemia Mystery Is Solved 2011-11-11T16:45:00.273Z
Their sudden destruction results in the liberation of large quantities of haemoglobin in the plasma, which turns deep-red in colour; and hence haemoglobinuria, which occurs only rarely in malaria, is a constant symptom in piroplasmosis. Encyclopaedia Britannica, 11th Edition, Volume 12, Slice 7 "Gyantse" to "Hallel" 2011-12-26T03:00:11.613Z
If “ozonic ether”—an ethereal solution of hydrogen peroxide—be now poured gently into the test-tube, a deep blue coloration is produced along the line of contact if haemoglobin be present. Encyclopaedia Britannica, 11th Edition, Volume 12, Slice 6 "Groups, Theory of" to "Gwyniad" 2011-12-16T03:00:12.320Z
This is more dangerous than it sounds, because the iron in haemoglobin is carrying oxygen, which means that there is potential for reactive oxgyen species to be released and cause havoc inside the cell. Pathogens that feed off human blood 2012-05-05T19:15:00.220Z
Here we present the genome sequence of Atlantic cod, showing evidence for complex thermal adaptations in its haemoglobin gene cluster and an unusual immune architecture compared to other sequenced vertebrates. The genome sequence of Atlantic cod reveals a unique immune system 2011-09-07T17:20:58.640Z
Today, we are looking at haemoglobin and the 'off scores' which are all linked to blood and the blood profile. In the blood? 2011-07-27T10:21:34Z
The technique takes advantage of the fact that compared with constituents of other tissues, haemoglobin in blood absorbs more light in the near-infrared spectrum. Psychiatric science: Thought experiment 2011-01-19T16:52:48.510Z
The reaction is due to the oxidation of the resin by the peroxide of hydrogen—such oxidation occurring only if haemoglobin be present to act as an oxygen-carrier. Encyclopaedia Britannica, 11th Edition, Volume 12, Slice 6 "Groups, Theory of" to "Gwyniad" 2011-12-16T03:00:12.320Z
The whole process of extracting iron from haemoglobin is actually fraught with dangers for the bacteria. Pathogens that feed off human blood 2012-05-05T19:15:00.220Z
Well-studied haemoglobin polymorphisms in Atlantic cod are indicative of functional molecular adaptation to thermal variation. The genome sequence of Atlantic cod reveals a unique immune system 2011-09-07T17:20:58.640Z
"At the moment, we are looking at blood profiles - and some of the key variables we look at are haemoglobin, and ," he told BBC News. In the blood? 2011-07-27T10:21:34Z
So monitoring the changes in haemoglobin concentration gives a site-specific read on blood flow and thus on neuronal activity. Psychiatric science: Thought experiment 2011-01-19T16:52:48.510Z
In high altitudes, there is less oxygen and so the amount of haemoglobin in blood increases. Waiting to exhale 2011-01-12T11:32:54Z
Once bound, the haemoglobin passes through the bacterial cell wall and into the interior of the cell. Pathogens that feed off human blood 2012-05-05T19:15:00.220Z
Two of the genes are linked to haemoglobin - the substance in blood that transports oxygen round the body. DNA clue to life at high altitude 2010-05-13T23:53:00Z
This protein, called haemoglobin, carries oxygen around in the blood of mammoths and other mammals. Mammoths had 'anti-freeze blood' 2010-05-02T18:58:00Z
One on radio astronomy and another on the structure of haemoglobin and myoglobin. 2010-02-04T13:57:00Z
In certain forms of anaemia it increases the number of the red corpuscles and also their haemoglobin content. Encyclopaedia Britannica, 11th Edition, Volume 2, Slice 6 "Armour Plates" to "Arundel, Earls of"
A further striking characteristic of haemoglobin is that it contains iron in its molecule. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
Two appear to contribute to lower levels of haemoglobin in the blood, which may help the body fight altitude sickness. DNA clue to life at high altitude 2010-05-13T23:53:00Z
The team found that mammoths possessed a genetic adaptation allowing their haemoglobin to release oxygen into the body at low temperatures. Mammoths had 'anti-freeze blood' 2010-05-02T18:58:00Z
It is very poisonous, uniting with the haemoglobin of the blood to form carbonyl-haemoglobin. Encyclopaedia Britannica, 11th Edition, Volume 5, Slice 3 "Capefigue" to "Carneades"
The origin of these pigments is yet uncertain, but it is probable that they are derived from the haemoglobin or red colouring matter of the blood. Encyclopaedia Britannica, 11th Edition, Volume 9, Slice 1 "Edwardes" to "Ehrenbreitstein"
It is proved, however, that the destruction of the haemoglobin is entirely effected there. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
The blood is usually deficient in haemoglobin, which is often only 40-50% of the normal. Encyclopaedia Britannica, 11th Edition, Volume 7, Slice 6 "Coucy-le-Château" to "Crocodile"
The researchers sequenced haemoglobin genes from the DNA of three Siberian mammoths preserved in the Siberian permafrost where they died tens of thousands of years ago. Mammoths had 'anti-freeze blood' 2010-05-02T18:58:00Z
It is a curious and noteworthy fact that in some invertebrate animals in which no haemoglobin occurs, we meet with its derivatives. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 6 "Cockaigne" to "Columbus, Christopher"
Chlorophyll is related chemically to the proteids; a decomposition product, phylloporphyrin, being very closely related to haematoporphyrin, which is a decomposition product of haemoglobin, the red colouring matter of the blood. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 3 "Chitral" to "Cincinnati"
In reptiles and amphibia the red corpuscles are also nucleated, but the stroma portion containing the haemoglobin is arranged in a thickened annular part encircling the nucleus. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
The blood is coloured red by haemoglobin in blood corpuscles. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 2 "Chicago, University of" to "Chiton"
Scientists then tested the "revived" mammoth proteins and confirmed that three highly unusual changes in the haemoglobin sequence allowed mammoth blood to deliver oxygen to cells even at very low temperatures. Mammoths had 'anti-freeze blood' 2010-05-02T18:58:00Z
In some worms the transparent skin allows the haemoglobin of the blood to be seen through the integument, and in certain fishes also the haemoglobin is visible through the integument. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 6 "Cockaigne" to "Columbus, Christopher"
The red cells are diminished, but usually are not below eighty per cent of the normal; the haemoglobin is greatly reduced, sometimes to thirty-five or forty per cent. Mother's Remedies Over One Thousand Tried and Tested Remedies from Mothers of the United States and Canada
The concentration of the haemoglobin in the corpuscles attains its maximum in the mammal and the bird. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
Insofar as haemoglobin hastens the departure of the excrementitious matter in urine out of the system, there is a daily loss of iron in the urine. Valere Aude Dare to Be Healthy, Or, The Light of Physical Regeneration
No influence was exerted on the corpuscles and the haemoglobin of the blood. The Project Gutenberg Encyclopedia Volume 1 of 28
In vertebrates the latter is generally accompanied by haemoglobin, but in invertebrates—with the exception of the pharyngeal muscles of the mollusca—it occurs alone. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 6 "Cockaigne" to "Columbus, Christopher"
The red blood cells are diminished, also the haemoglobin. Mother's Remedies Over One Thousand Tried and Tested Remedies from Mothers of the United States and Canada
In contrast with this, in higher vertebrates the blood pressure is high and the haemoglobin content of the blood is high, consequently both rate of blood-flow and oxygen-content are high. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
Such eggs might be justly classed as haemoglobin eggs, and they would be a godsend to our boys suffering from anaemia due to wounds or operations. Valere Aude Dare to Be Healthy, Or, The Light of Physical Regeneration
The oxygen contained in that fluid, and destined for consumption by the tissues, is retained by the influence of alcohol in its combination with the haemoglobin or colouring matter of the red blood corpuscles. The Project Gutenberg Encyclopedia Volume 1 of 28
Like haemoglobin, it acts as an oxygen-carrier in respiration, but it takes no part in surface coloration. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 6 "Cockaigne" to "Columbus, Christopher"
Anaemia, or Anemia.—This may be defined as a reduction of the amount of blood as a whole or of its corpuscles, or of certain of its more important constituents, such as albumin and haemoglobin. Mother's Remedies Over One Thousand Tried and Tested Remedies from Mothers of the United States and Canada
In the lower vertebrates the blood pressure is low and the haemoglobin content of the blood is low, consequently both rate of blood-flow and oxygen-content are low. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
What could be more effective in treating the anaemic condition of wounded and crippled boys, and in treating the same condition in women industrial workers, than haemoglobin eggs? Valere Aude Dare to Be Healthy, Or, The Light of Physical Regeneration
Lutein is a colouring matter sometimes found in blood-clots, and probably derived from haemoglobin. Hormones and Heredity
No direct connexion has been traced between the chlorophyll eaten with the food and the haemoglobin of blood and muscle. Encyclopaedia Britannica, 11th Edition, Volume 6, Slice 6 "Cockaigne" to "Columbus, Christopher"
Chlorosis, a primary anemia chiefly of young girls, characterized by marked relative decrease of haemoglobin. Mother's Remedies Over One Thousand Tried and Tested Remedies from Mothers of the United States and Canada
Most of the above symptoms and organic changes are directly due to diminished respiratory interchange from the loss of haemoglobin, and to its effect on the various organs involved. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
In some of the Nemertina the blood is already coloured, and the red colouring matter is real haemoglobin, connected with elliptical discoid cells, as in the Vertebrates. The Evolution of Man — Volume 2
The violet, and especially these latter ultra-violet rays, redden the life stream by increasing the haemoglobin—that crystallizable body which forms so large a portion of the coloured corpuscles of the blood. The Art of Living in Australia ; together with three hundred Australian cookery recipes and accessory kitchen information by Mrs. H. Wicken
One gram of haemoglobin crystals can combine with 1.34 cc. of oxygen. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
Certain mesodermic cells, resembling those of the connective tissue, collect masses of haemoglobin, and from these elaborate red blood corpuscles which thus come to lie in the fluid part of the cell. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
One important food substance, oxygen, is, however, only partly carried in solution, being mainly combined with haemoglobin in the red corpuscles. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
Thus in a given solution of haemoglobin the amount of it which is combined with oxygen depends absolutely on the oxygen concentration. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
In association with this, oxyhaemoglobin has a typical bright red colour, whereas haemoglobin is dark purple. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
As haemoglobin is the medium of respiratory interchange, its diminution causes obvious symptoms, which are much more easily appreciated by the patient than those caused by alterations in the plasma or the leucocytes. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea"
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