| 单词 | growth factor |
| 例句 | “Learning happens when brain cells make new connections. The strength of these connections is enhanced by a group of proteins in the brain called growth factors.” The Smartest Kid in the Universe 2020-12-01T00:00:00Z Platelet rich plasma therapy, in which growth factors from the patient’s own blood are injected into the scalp, can stimulate hair growth, too. What Black Women Need to Know About Hair Loss 2018-04-02T04:00:00Z What’s more, aerobic exercise helps release human growth factor hormones that promote healing in the tendons and connective tissues, said Stephen Pribut, a D.C. podiatrist. Maintaining fitness — not resting — may be key to recovering from an injury 2016-04-25T04:00:00Z He has made significant contributions in several of these areas, including the use of imaging technology to locate genes associated with mental disorders, and research on growth factors and stem cells. This is your brain on murder: What the mind of a psychopath looks like 2014-03-09T18:30:00Z The cells feed on a complex broth that contains nutrients like carbohydrates and amino acids, and some type of growth factor, to become muscle, fat or connective tissue. The New Secret Chicken Recipe? Animal Cells. 2022-02-15T05:00:00Z The team also looked at proteins in the blood called growth factors, which are linked with some cancers. Alcohol-free months are all the rage – but will a sober October lead to long-term health benefits? 2018-09-17T04:00:00Z When the gene is mutated, it overproduces the corresponding human epidermal growth factor receptor 2 protein to trigger unhinged cell division. Precision Cancer Drugs Glitter with Promise—If You Can Get Them 2023-11-03T04:00:00Z To make stem cells differentiate, scientists "feed" them with growth factors and embed them in a nutrient solution. Controlling organoids with light 2023-10-30T04:00:00Z The mechanism involves betacellulin, a protein growth factor that plays multiple positive roles in the body but also contributes to liver fibrosis, or scarring, and the progression to cirrhosis and liver cancer. Researchers uncover mechanism for treating dangerous liver condition 2023-10-25T04:00:00Z The hiPSCs were differentiated into neural progenitor cells for two different layers of the cerebral cortex, by using specific combinations of growth factors and chemicals. Scientists develop 3D printing method that shows promise for repairing brain injuries 2023-10-04T04:00:00Z “The idea behind PRP is that there’s some growth factors in there that might stimulate a healing response,” Dr. Bowman said. Q&A: What's next for Shohei Ohtani and the Angels in the wake of his torn UCL? 2023-08-24T04:00:00Z Ranibizumab injections into the eye can block the action of vascular endothelial growth factor, which promotes growth of new blood vessels. NHS to offer sight-saving drug to premature babies 2023-07-03T04:00:00Z Xylem is the tissue responsible for the storage and long-distance transport of water and nutrients, as well as the transfer of water-soluble growth factors from the organs of synthesis to the target organs. Fundamentals of Biology 2015-01-01T00:00:00Z Xylem is the tissue responsible for long-distance transport of water and minerals, the transfer of water-soluble growth factors from the organs of synthesis to the target organs, and storage of water and nutrients. Concepts of Biology 2013-04-25T00:00:00Z One result that the team wasn’t expecting came from a gene called E.G.F., or epidermal growth factor; or rather, from the lack of it. Unlocking the Genes That Made Whales Into Giants 2023-01-19T05:00:00Z They also experienced sharp reductions in cancer-related growth factors — a particularly important finding, the researchers noted, because even low levels of alcohol consumption can increase the risk of many cancers. The benefits of ‘Dry January’ last longer than a month, studies show 2022-12-27T05:00:00Z It’s a serum that uses a combination of stem-cell-derived growth factors, peptides and hyaluronic acid to create an environment where the skin can repair and protect itself. 7 items to nourish the soul headed into the extended culinary holiday in L.A. 2022-11-11T05:00:00Z Most growth factors bind to cell-surface receptors that are linked to tyrosine kinases. Biology for AP Courses 2022-06-09T00:00:00Z A key step involves placing the embryos in an incubator outfitted with a Ferris wheel–like device, which rotates the embryos inside bottles of liquid filled with nutrients and growth factors. With innovative bioreactor as womb, mouse stem cells transform into organ-filled embryos 2022-08-02T04:00:00Z The researchers suggest salivary gland ionocytes probably regulate saliva pH and viscosity and secrete the growth factor that is crucial for salivary gland repair. ‘Frog Skin’ Cell Type Found in Mammal Mouths 2022-07-22T04:00:00Z Saliva also contains epidermal growth factor, which might have given rise to the adage “a mother’s kiss can heal a wound.” Anatomy and Physiology 2013-06-19T00:00:00Z The researchers cannot say for sure if the jumping genes are responsible for the absence of the growth factor genes. ‘Evolution Gone Crazy’: What Makes Sea Dragons So Strange 2022-07-07T04:00:00Z Cell growth is almost always stimulated by external signals called growth factors. Biology for AP Courses 2022-06-09T00:00:00Z Conaghan investigates new drugs for arthritis, including a growth factor called sprifermin that appears to slow the loss of cartilage in some patients. Your Body May Be Able to Repair Its Arthritic Joints with Help from Drugs or Surgery 2022-06-18T04:00:00Z Although the cells have not yet been directly observed in human salivary glands, the growth factor they produce has been isolated in human saliva. ‘Frog Skin’ Cell Type Found in Mammal Mouths 2022-07-22T04:00:00Z Examples of proto-oncogene products include cell-surface receptors for growth factors, or cell-signaling molecules, two classes of molecules that can promote DNA replication and cell division. Anatomy and Physiology 2013-06-19T00:00:00Z It was of the type ER+/PR+, positive for the hormones estrogen and progesterone, and HER2-, negative for human epidermal growth factor receptor 2. Review | A former nurse calls out the lack of compassion in health care 2022-05-13T04:00:00Z In addition, other nutrients and environmental conditions can be characterized as growth factors. Biology for AP Courses 2022-06-09T00:00:00Z Researchers found that early stage melanomas which are at risk of spreading secrete a growth factor which causes the reduction, or downregulation, of certain proteins in the skin overlying the tumour. Skin cancer: Newcastle University test predicts spread of melanoma 2022-01-14T05:00:00Z The first step was to check the level of one of the growth factors usually stimulated by this kind of brain tumor. What Was Causing the Strange Grooves in the Man’s Scalp? 2021-12-29T05:00:00Z These cells are located outside the sarcolemma and are stimulated to grow and fuse with muscle cells by growth factors that are released by muscle fibers under certain forms of stress. Anatomy and Physiology 2013-06-19T00:00:00Z The real work of regeneration happens, she explains, when the cells produce growth factors, which in turn affect heart repair by reducing inflammation and stimulating the development of new heart muscle. Cells or Drugs? The Race to Regenerate the Heart 2021-12-03T05:00:00Z During the formation of the neural system, special signaling molecules called growth factors signal some cells at the edge of the ectoderm to become epidermis cells. Biology for AP Courses 2022-06-09T00:00:00Z The cells grow in nutrient-rich media typically consisting of a unique, species-specific combination of glucose, amino acids, peptides, fatty acids, vitamins, salts and growth factors such as hormones, recombinant proteins and cytokines. No Bones, No Scales, No Eyeballs: Appetite Grows for Lab-Grown Seafood 2021-11-23T05:00:00Z Bone marrow aspirate contains growth factors that decrease inflammation and promote healing, while micro-fragmented adipose tissue is marketed for cushioning and support. Could platelet-rich plasma injections help avoid knee surgery? More studies may give answer. 2021-11-05T04:00:00Z They also secrete a variety of growth factors essential for growth and repair of tissue, particularly connective tissue. Anatomy and Physiology 2013-06-19T00:00:00Z These foods increase insulin and insulinlike growth factor, hormones that can foster acne development. The Emotional Toll of Adult Acne 2021-10-25T04:00:00Z If the signaling by growth factors were disrupted, then the entire ectoderm would differentiate into neural tissue. Biology for AP Courses 2022-06-09T00:00:00Z When NHS England rolled out wider placental growth factor testing in 2019, it said evidence suggested it sped up diagnosis, which could save lives. Pregnancy: Some women in Wales to get pre-eclampsia test 2021-10-15T04:00:00Z A protein in the seeds, called a growth factor, is harvested, milled and purified before it can be used. The plant with seeds that can grow meat 2021-10-11T04:00:00Z While many platelets are stored in the spleen, others enter the circulation and are essential for hemostasis; they also produce several growth factors important for repair and healing. Anatomy and Physiology 2013-06-19T00:00:00Z Some of these substances, including growth factors and molecules known as cytokines, also make dorsal horn neurons overly excitable, and drugs blocking that hyperactivity should help undercut excessive sensitivity. Toward Better Pain Control 2021-10-10T04:00:00Z On the extracellular side of the membrane, one or more sites are present that bind to signaling ligands such as insulin or growth factors. Biology for AP Courses 2022-06-09T00:00:00Z Multiply that number by the “growth factor” of your tree. Become an Outdoor Scientist 2021-05-29T04:00:00Z While the first growth factors came from animals, it is hoped this barley plant method will be cheaper and scalable. The plant with seeds that can grow meat 2021-10-11T04:00:00Z In general, these products try to rehydrate the skin and thereby fill out the wrinkles, and some stimulate skin growth using hormones and growth factors. Anatomy and Physiology 2013-06-19T00:00:00Z Manipulating these intracellular signals, combined with the addition of a widening field of neuron growth factors, offers hope to ramp up the extent, speed and accuracy of regeneration. Readers Respond to the January 2021 Issue 2021-05-23T04:00:00Z External influences, such as growth factors, play a large role in carrying the cell past the G1 checkpoint. Biology for AP Courses 2022-06-09T00:00:00Z The “growth factor” is an average estimate of your tree’ species’ growth over time. Become an Outdoor Scientist 2021-05-29T04:00:00Z Research at Orf Genetics is now on-going to find out which barley produces the best growth factors. The plant with seeds that can grow meat 2021-10-11T04:00:00Z Anabolic hormones are required for the synthesis of molecules and include growth hormone, insulin-like growth factor, insulin, testosterone, and estrogen. Anatomy and Physiology 2013-06-19T00:00:00Z We stained the brains in ways that highlighted the activated form of the growth factor as well as the astrocytes that produced it. Damage to a Protective Shield around the Brain May Lead to Alzheimer’s and Other Diseases 2021-05-10T04:00:00Z These membrane receptors provide extracellular attachment sites for effectors like hormones and growth factors, and they activate intracellular response cascades when their effectors are bound. Biology for AP Courses 2022-06-09T00:00:00Z Regional growth factors, high traffic volumes and congestion causing backups, resulting in long travel times, would be carefully examined along with conclusions on what needs to be done to alleviate high-traffic volumes and congestion. Why Seattle and the rest of the state should care about Highway 2 2021-04-05T04:00:00Z We found a high level of zinc in the hippocampus, and we began following a trail that led us to growth factors that are involved in brain development. Neuroscientist’s research helped unearth how human brains can make new cells 2021-02-05T05:00:00Z The isolated stem cells are then grown in culture using the appropriate hemopoietic growth factors, and analyzed or sometimes frozen for later use. Anatomy and Physiology 2013-06-19T00:00:00Z Fetal bovine serum, a rich source of growth factors, is commonly added to mouse stem-cell cultures. A menagerie of stem-cell models 2020-09-21T04:00:00Z Cell division and growth are almost always stimulated by external signals called growth factors; left unregulated, cell growth leads to cancer. Biology for AP Courses 2022-06-09T00:00:00Z This switch affects growth factors, immune signals and other chemicals. How Good a Diet Is Intermittent Fasting? 2020-09-09T04:00:00Z We were interested in nerve growth factors and wondered if these factors were the source of this new growth that we were observing in the brains of the animals we studied. Neuroscientist’s research helped unearth how human brains can make new cells 2021-02-05T05:00:00Z Platelets are essential for the repair of blood vessels when damage to them has occurred; they also provide growth factors for healing and repair. Anatomy and Physiology 2013-06-19T00:00:00Z And when Menzorov used a medium specifically for growing neurons, he wound up with fat-storing and bone cells instead — cells that typically require specific growth factors to form. A menagerie of stem-cell models 2020-09-21T04:00:00Z A researcher intends to test the effects of several growth factors on the differentiation of plant tissue. Biology for AP Courses 2022-06-09T00:00:00Z The investigators suggest that this raises blood levels of insulin and other growth factors. Older people can still get celiac disease 2020-06-21T04:00:00Z We also took skin fibroblasts, which are known to divide and grow, and overexpressed nerve growth factors and then inserted them into the hippocampus. Neuroscientist’s research helped unearth how human brains can make new cells 2021-02-05T05:00:00Z It is a hemopoietic growth factor that prompts lymphoid stem cells to leave the bone marrow. Anatomy and Physiology 2013-06-19T00:00:00Z Some cells differentiate better under the influence of growth factors from their own species, rather than from a model organism. A menagerie of stem-cell models 2020-09-21T04:00:00Z The authors sequentially added growth factors to the stem cells. Regenerative medicine could pave the way to treating baldness 2020-06-02T04:00:00Z A plethora of growth factors are involved in the development of these dopaminergic neurons in the immature brain, but these factors are either lacking or expressed at much lower levels in the adult brain. Parkinson’s disease grafts benefit from well-timed growth factor 2020-05-25T04:00:00Z We found that when we put cells expressing a certain growth factor in a dish with neural progenitor cells, they grew like crazy. Neuroscientist’s research helped unearth how human brains can make new cells 2021-02-05T05:00:00Z A node at the caudal or “tail” end of the primitive streak emits growth factors that direct cells to multiply and migrate. Anatomy and Physiology 2013-06-19T00:00:00Z But for other growth factors, the species of origin is less important, she says. A menagerie of stem-cell models 2020-09-21T04:00:00Z Animal studies suggest that they might not create new muscle, but secrete growth factors that rejuvenate the existing heart tissue, a process known as the paracrine effect4. Revealed: First trial of pioneering stem-cell treatment for heart disease performed in China 2020-05-12T04:00:00Z The introduction of growth factors into the adult brain, therefore, might be a way to improve the success of cell-engraftment approaches. Parkinson’s disease grafts benefit from well-timed growth factor 2020-05-25T04:00:00Z One growth factor Strandwitz identified turned out to be the key to launching his entrepreneurial dreams. Meet the ‘psychobiome’: the gut bacteria that may alter how you think, feel, and act 2020-05-07T04:00:00Z Dr. Cohen determined that this early development was spurred by a substance similar to NGF, which he called epidermal growth factor, or EGF. Stanley Cohen, Nobel Prize-winning scientist who studied cellular growth, dies at 97 2020-02-06T05:00:00Z In those cases, glypicans are thought to bind to and regulate the signalling of growth factors that promote tumour growth. Brain tumours manipulate neighbouring synapses 2020-01-28T05:00:00Z To the team’s surprise, the snake stem cells responded to the same growth factors that work on human and mouse cells. Tiny organs grown from snake glands produce real venom 2020-01-23T05:00:00Z But when she tried to board her plane at Atlanta airport in September 2016, US federal agents confiscated the growth factors. United States drops charges against two more scientists after Iran prisoner swap 2019-12-12T05:00:00Z He began to track down growth factors to keep recalcitrant species going. Meet the ‘psychobiome’: the gut bacteria that may alter how you think, feel, and act 2020-05-07T04:00:00Z He called the protein the epidermal growth factor receptor, or EGF receptor. Stanley Cohen, Nobel Prize-winning scientist who studied cellular growth, dies at 97 2020-02-06T05:00:00Z Pegaptanib binds to and blocks the function of the protein vascular endothelial growth factor, leading to a reduction in the growth and permeability of blood vessels in the eye. RNA therapies explained 2019-10-15T04:00:00Z When the scientists removed the growth factors, the cells began to morph into the epithelial cells that produce venom in the glands of snakes. Tiny organs grown from snake glands produce real venom 2020-01-23T05:00:00Z A 2006 study in Neuroscience found that exercise spurs the brain to release growth factors that promote new connections between neurons, keeping the brain healthy. The longevity files: A strong grip? Push-ups? What actually can help you live to a ripe old age. 2019-09-27T04:00:00Z The first “big basket” of changes includes a rise in growth factors, including insulin and those that promote blood vessel formation, he explains. Losing Weight May Lower the Risk of Cancer 2019-09-26T04:00:00Z The engineered strain of cells then had to be multiplied in a special brew of nutrients and growth factors. The Promise and Price of Cellular Therapies 2019-07-15T04:00:00Z He injected a cancer drug, an antibody to vascular endothelial growth factor A, into the eye of the patient. A Streamlined Pathway to Drug Approval 2019-06-26T04:00:00Z Three Iranian biologists are facing trial in a US court over charges that they violated trade sanctions by attempting to export chemicals known as growth factors, which are commonly used in medical research. Iranian biologists face US trial for trying to take proteins out of the country 2019-06-23T04:00:00Z Researchers looking for ways to grow HSCs in large numbers in the lab had tried using growth factors without much success. Blood stem cells produced in vast quantities in the lab 2019-05-29T04:00:00Z He notes that, unlike other gels, this one does not include growth factors and other biological signaling molecules, instead relying on the body to supply its own. This injectable gel could one day rebuild muscle, skin, and fat 2019-05-01T04:00:00Z Why don’t we give them another two days and a little squeeze of a growth factor?’ The Promise and Price of Cellular Therapies 2019-07-15T04:00:00Z At one point, Dr. Pourcho says that platelets release growth factors that tell the brain which types of stem cells to send to the site of an injury. Hospitals plunge into market of experimental injections as patients try to avoid surgery 2019-04-04T04:00:00Z But when she tried to board her plane at the Atlanta airport in September 2016, US border agents searched her luggage and confiscated the growth factors. Iranian biologists face US trial for trying to take proteins out of the country 2019-06-23T04:00:00Z Some of those changes can affect growth factors for both the placenta and the embryo, Dr. Eisenberg and colleagues suggested. The Risks to Babies of Older Fathers 2019-03-25T04:00:00Z She said they also contained very few “growth factors” — substances that many companies often claim stimulate healing. ‘Miraculous’ stem cell therapy has sickened people in five states 2019-02-26T05:00:00Z Every time Bashiri added a drop of a chemical—a growth factor, say—he announced the action out loud. The Promise and Price of Cellular Therapies 2019-07-15T04:00:00Z They found that the most disrupted genes were those for growth factors, proteins that act like a kind of brain fertilizer. Opinion | How to Be More Resilient 2018-12-15T05:00:00Z All that is needed is the right number and combination of cells, growth factors and, sometimes, a means of physically confining the cells, such as in microwells8. Debate ethics of embryo models from stem cells 2018-12-11T05:00:00Z For example, “When hair follicles form, their spacing is determined by gradients of growth factors,” he says. Unlocking the secrets of scar-free skin healing 2018-11-20T05:00:00Z If these products have any effect on patients, Fortier said, “it’s not through live cells or growth factors.” ‘Miraculous’ stem cell therapy has sickened people in five states 2019-02-26T05:00:00Z The authors found that VCT cells express receptors that promote differentiation and are stimulated by growth factors produced by various placental cells. Cell atlas reveals the landscape of early pregnancy 2018-11-13T05:00:00Z Dr. Akil and colleagues at the Pritzker Neuropsychiatric Disorders Research Consortium found that one growth factor that is depleted in depressed brains, called fibroblast growth factor 2, also plays a role in resilience. Opinion | How to Be More Resilient 2018-12-15T05:00:00Z You need nutrients and then you need growth factor, and that’s the hard part. These are the technology advances that could end animal farming 2018-11-09T05:00:00Z Still other scientists are investigating nerve growth factors, chemical compounds that are injected at the site of an injury to promote repair. Once Paralyzed, Three Men Take Steps Again With Spinal Implant 2018-10-31T04:00:00Z It is also more expensive because it uses purified growth factors rather than serum. Tapping into the brain’s star power 2018-10-30T04:00:00Z Sluggish lymphangiogenesis does not result from a shortage of the growth factor, he says. New therapies could treat tissue swelling that afflicts cancer surgery patients and others 2018-10-10T04:00:00Z Another growth factor, BDNF, promotes neurogenesis in animals and may enhance resilience in humans. Opinion | How to Be More Resilient 2018-12-15T05:00:00Z By isolating those cells and growing them in a dish alongside a bone growth factor protein, the scientists created skeletal stem cells. Skeletal stem cells found in humans for first time, promising new treatments for fractures and osteoporosis 2018-09-20T04:00:00Z “Now we understand what it takes,” he says, referring to the trifecta of axon growth factors, laminin and chemical bait placed along the path to lure the axon. Growth Cocktail Helps Restore Spinal Connections in the Most Severe Injuries 2018-08-30T04:00:00Z We’re still learning about hunger and appetite hormones, and there’s a new insulin growth factor, too. How hormones went from theoretical to overhyped in one century 2018-08-07T04:00:00Z And they didn't need to keep adding growth factors to make this growth happen. Engineered pig lung transplant 'success' 2018-08-03T04:00:00Z Perhaps someday we might be able to protect young people exposed to violence and adversity by supplementing them with neuroprotective growth factors. Opinion | How to Be More Resilient 2018-12-15T05:00:00Z “We see health as a growth factor for us over the long term,” he said. Investors Step Back From Social-Media Highfliers 2018-07-27T04:00:00Z A third of adenocarcinoma cancers carry a mutant gene called KRAS, which the researchers show requires the activity of any of four “EGFR/ERBB growth factor receptors” to drive cell proliferation. Existing treatment could be used for 'untreatable' form of lung cancer 2018-06-21T04:00:00Z When they are grown in the appropriate conditions, for example with specific growth factors, the stem cells self-organize into structures in which the different cell types are arranged similarly to the in vivo tissue. Stem-cell culture moves to the third dimension 2018-06-10T04:00:00Z Histogen is convinced that these cells stimulate “growth factors” that signal hair formation. Is the Age-Old Quest for a Baldness Cure Reaching Its End? 2018-06-07T04:00:00Z Further analysis will also be needed to determine whether a single telocyte population is responsible for niche function, or if different populations orchestrate the many stromal growth factors and inhibitors that regulate intestinal stem-cell function. Debate over the identity of an intestinal niche-cell population settled 2018-06-05T04:00:00Z He thinks that instead they release growth factors that help to regenerate the damaged muscle. ‘Reprogrammed’ stem cells approved to mend human hearts for the first time 2018-05-28T04:00:00Z They also treated the cells with a series of growth factors that stimulated them to form the various cell layers seen in early embryos. Hybrid Human–Chicken Embryos Illuminate Key Developmental Milestone 2018-05-24T04:00:00Z Those growth factors prompted some of the cells to express the genetic hallmarks of an organizer. Elusive master organizer of human embryo growth seen for the first time 2018-05-23T04:00:00Z Cardiovascular exercise decreases stress biomarkers, releases growth factors that support the immune system and improves memory. Why Exercise Alone May Not Be the Key to Weight Loss 2018-04-11T04:00:00Z Kieda’s lab combines melanoma and endothelial cells in a matrix composed of collagen, growth factors and a 3D scaffold called Matrigel. Cancer research with a human touch 2018-04-09T04:00:00Z Among the suspected reasons: chronic low-level inflammation, too much insulin, excess hormones and growth factors released by fat tissue, and metabolic abnormalities. Why Pancreatic Cancer Is on the Rise 2018-04-09T04:00:00Z A critical role for transcription factor Smad4 in T cell function that is independent of transforming growth factor β receptor signaling. Reversing SKI–SMAD4-mediated suppression is essential for TH17 cell differentiation 2017-10-24T04:00:00Z Turner, N. & Grose, R. Fibroblast growth factor signalling: from development to cancer. Association analysis identifies 65 new breast cancer risk loci 2017-10-22T04:00:00Z Mutation in transforming growth factor beta induced protein associated with granular corneal dystrophy type 1 reduces the proteolytic susceptibility through local structural stabilization. Structure of phycobilisome from the red alga Griffithsia pacifica 2017-10-17T04:00:00Z Stem cells collected from the patients' own bone marrow were cultured and stimulated into producing nerve-cell growth factors, then transplanted back into the patients. Drug therapy: On the treatment trail for ALS : Nature : Nature Research 2017-10-17T04:00:00Z There are drugs like growth factor 1 for which there are no reliable tests. The Home Run Explosion Is Not Exactly Beyond Suspicion 2017-09-21T04:00:00Z Likewise, they didn’t undertake a proper risk assessment of the procedure, nor did Macchiarini’s team seek government permits for the plastic windpipes, stem cells, and chemical “growth factors” they used. Dr Con Man: the rise and fall of a celebrity scientist who fooled almost everyone 2017-09-01T04:00:00Z Clevers's mix of growth factors grows organoids consisting primarily of epithelial cells, so his technique doesn't work for the brain and other organs with few or no epithelial cells. This scientist is building miniature guts, livers, and lungs that could save your life one day 2017-08-23T04:00:00Z The cells may also release signaling molecules of their own, known as growth factors. Scientists Discover a Key to a Longer Life in Male DNA 2017-06-16T04:00:00Z Estrogen and growth factors also surge early in pregnancy. Winning While Pregnant: How Athletes Do It 2017-04-27T04:00:00Z "Fetal lungs are designed to function in fluid. We simulate that environment ... allowing the lungs and other organs to develop while supplying nutrients and growth factors," he said. Scientists develop fluid-filled artificial womb to help premature babies 2017-04-26T04:00:00Z Before birth, amniotic fluid flows into their lungs, bringing growth factors crucial for proper lung development. Hope for preemies as artificial womb helps tiny lambs grow 2017-04-25T04:00:00Z The Harvard researchers showed that many of the effects they saw were attributable to a growth factor called GDF11, which is in higher concentration in young blood than in old blood. Giving young blood to older animals raises tantalizing possibilities for people 2017-04-14T04:00:00Z Writing in the journal PNAS, the team reveal the missing link is a protein, known as vascular endothelial growth factor, which is made in the region of the pituitary gland that detects melatonin. Why do sheep get horny in winter? Because the light is baaad, says study 2017-03-06T05:00:00Z But Longo notes that levels of insulin-like growth factor 1, a hormone that promotes aging in rodents and other lab animals, plunged in the low-cal group. Five-day fasting diet could fight disease, slow aging 2017-02-15T05:00:00Z Scientists designed Tarceva to block an enzyme associated with epidermal growth factor receptor, or EGFR, a protein believed to play a role in the formation and growth of cancer. This $7,800-a-month cancer drug caused rashes and rarely worked. Now Trump could make FDA approvals even easier 2017-02-04T05:00:00Z Instead, the stem cells released growth factors that made existing bone cells in the mice multiply and mature more effectively. Pregnant women's stem cells could treat osteoporosis, say scientists 2016-12-20T05:00:00Z Instead of being a drop-in, friendly replacement tissue, these grafts rapidly die from a lack of nutrients, appropriate growth factors and innervation4. Perspective: Work with, not against, biology : Nature : Nature Research 2016-12-06T05:00:00Z Instead, the cells seem to secrete growth factors that encourage the formation of new neurons and blood vessels, and foster connections called synapses between neurons. Neuroscience: New nerves for old : Nature : Nature Research 2016-12-06T05:00:00Z Developed in Cuba and available to patients there since 2011, it works by targeting a protein called epidermal growth factor, or E.G.F., that enables lung cancer cells to grow. A Hot Souvenir From Cuba for Some Americans: Cancer Vaccine 2016-11-14T05:00:00Z And in healthy older women or women with mild cognitive impairment, treatment with insulin-like growth factor I for 1 year showed no effect on bone density, bone strength, mood or memory93. Ageing, neurodegeneration and brain rejuvenation : Nature : Nature Research 2016-11-08T05:00:00Z They used a mixture of proteins and growth factors to prod both types of stem cells into becoming the primordial germ cells that are the precursor of eggs, the scientists said. Japanese Scientists Master Egg Creation Process in Mice 2016-10-17T04:00:00Z Nerve growth factor and the receptor are important to the proper development of the nervous system. How naked mole rats conquered pain—and what it could mean for us 2016-10-11T04:00:00Z Exercise increases the level of brain chemicals called growth factors, which help make new brain cells and establish new connections between brain cells to help us learn. How to Hack Your Workout for Brain Health 2016-10-11T04:00:00Z And high levels of three other biomarkers -- vascular endothelial growth factor, C-reactive protein, and tumor necrosis factor receptor 2 -- also indicated a similar heightening of stroke risk, the investigators said. Blood Test Might Someday Predict Your Stroke Risk 2016-08-24T04:00:00Z They are “activated with the patient’s growth factors,” then infused back into the individual. Want to enroll in a clinical trial? NIH database is huge — but lacks a few key details 2016-07-26T04:00:00Z “All Occasions is still the lion, but the growth factor is Marbella,” Brown said of the two divisions that often accompany each other on a project. Company brings all the furnishings, regardless of the party 2016-07-09T04:00:00Z The pain pathway is kicked off when a substance called nerve growth factor is released by injured or inflamed cells. How naked mole rats conquered pain—and what it could mean for us 2016-10-11T04:00:00Z Researchers found that neratinib is particularly helpful in women with HER2-positive breast cancer, in which a protein called human epidermal growth factor receptor 2 promotes the growth of cancer cells. Innovative Trials Produce Promising Breast Cancer Drugs 2016-07-07T04:00:00Z Platelets, the blood cells that promote clotting, contain hundreds of proteins, called growth factors, that are important in repairing injuries. I’ll never go through shoulder surgery again, so here’s what I did 2016-07-01T04:00:00Z Outside the United States, doctors have administered small doses of human growth hormone and other so-called “growth factors” on stem cells to grow ligament tissue in labs before injecting them into a patient. Angels' pitchers trying stem cell treatment instead of Tommy John surgery 2016-06-28T04:00:00Z The researchers will look at markers of inflammation and metabolism, including levels of insulin, insulinlike growth factor and hormones that regulate fat storage. Putting Breast Cancer on a Diet 2016-06-27T04:00:00Z Epidermal growth factor receptor is a type of protein found on the surface of cells in the body. Drugmakers pay $67 million to settle claims they exaggerated cancer drug's effectiveness 2016-06-07T04:00:00Z The first artificial genes were synthesized in the 1970s and were successfully incorporated into bacteria and other organisms to produce life-saving growth factors, including insulin. The Brave New World of the Synthetic Human Genome 2016-06-03T04:00:00Z It's also possible that excess fat increases cancer risk because it promotes the release of hormones such as insulin, human growth factors and other inflammatory chemicals into the bloodstream, they added. Alcohol, Processed Meats May Raise Stomach Cancer Risk 2016-04-20T04:00:00Z But HGH is prohibited by Major League Baseball's drug program, and the use of growth factors is banned domestically by the Food and Drug Administration. Angels' pitchers trying stem cell treatment instead of Tommy John surgery 2016-06-28T04:00:00Z Some of the research focuses on the drugs used to treat diabetes, since they regulate insulin and growth factors that are also involved in tumor growth. This Diabetes Drug Promotes Tumor Spread In Mice: Study 2016-04-13T04:00:00Z Experts say extra fat may produce hormones and growth factor molecules that encourage cells to replicate, increasing the chance of tumours forming. Obesity 'likely culprit' behind womb cancer rise - BBC News 2016-04-12T04:00:00Z The tumor secretes a protein called growth hormone that signals the liver to produce a substance called insulin-like growth factor 1, or IGF 1, which in turn tells cells throughout the body to start proliferating. Think Like a Doctor: Packing on the Pounds Solved! 1464-02-07T05:00:00Z The shots deliver drugs that fight a substance called vascular endothelial growth factor, and thus shrink the growth of what amounts to an abnormal blood vessel harming the retina. Fighting Macular Degeneration 2016-03-19T04:00:00Z Cancer cells grow rapidly and uncontrollably, and growth factors are crucial for cancer to progress, Andersen said. Diabetes Treatment May Affect Breast Density 2016-03-09T05:00:00Z According to study co-author Stephanie Melkonian, high-glycemic diets are linked to insulin resistance, which in turn may encourage the activity of certain cellular "growth factor" chemicals that are known to play a role in cancer. Can Certain 'Poor Carb' Diets Raise Nonsmokers' Lung Cancer Risk? 2016-03-04T05:00:00Z The scientists then recreated the chemical environment that sperm cells need to grow, including early development factors and sex hormones including testosterone, follicle stimulating hormone and a growth factor from the pituitary gland. It’s Now Possible to Make Mouse Sperm in a Lab 2016-02-25T05:00:00Z Mitosomal growth factors, stem cells and pig brain peptide: He talked of all with a chemist’s ease. Following the Names in the Al Jazeera Doping Report 2016-01-05T05:00:00Z There is also a new drug target: a substance called platelet-derived growth factor that causes abnormal vessel growth as well. Fighting Macular Degeneration 2016-03-19T04:00:00Z As the table shows, when you add the growth factors together, you get a doubling of the Hispanic population in Clark. Las Vegas encapsulates problems facing the GOP 2015-12-15T05:00:00Z However, Jain agreed that the downstream effect of a high-glycemic diet on cellular growth factors might explain the link to lung cancer risk. Can Certain 'Poor Carb' Diets Raise Nonsmokers' Lung Cancer Risk? 2016-03-04T05:00:00Z This particular gene helps regulate a protein known as "nerve growth factor." Genetic Abnormality May Explain Health Complications of Down Syndrome 2015-12-14T05:00:00Z The subtype of 'triple-receptor-negative' breast cancer is particularly difficult to treat because these cancers do not respond to signals from any of the breast growth hormones: oestrogen, progesterone and human epidermal growth factor 2. A tumour through time : Nature : Nature Publishing Group 2015-11-17T05:00:00Z Vasotide prevents the excessive growth of blood vessels, termed angiogenesis, by stopping a protein called vascular endothelial growth factor from binding to two receptors on blood-vessel walls, the study said. How the Brain Regulates Simultaneous Pains 2015-10-26T04:00:00Z The fractures create blood clots, which attract naturally occurring stem cells and growth factors. Implanting Lab-Grown Cartilage to Fix Damaged Knees 2015-10-05T04:00:00Z “Wall Street’s going to want to know what the next big growth factor is” for Monsanto, said Bill Selesky, analyst with Argus Research. Monsanto to Chart Growth Plan as Farmers Feel Squeezed 2015-10-03T04:00:00Z For example, RCAN1 also plays a role in regulating nerve growth factor in an area of the brain linked to Alzheimer's disease. Genetic Abnormality May Explain Health Complications of Down Syndrome 2015-12-14T05:00:00Z The final product is low in antibodies and high in growth factors – a perfect food, if you will, for the muscle tissue being cultivated for in vitro meat. Is company's claim of meat without murder too good to be true? 2015-09-05T04:00:00Z What was most valuable about that class wasn't the grade – I received a B – but the growth factor. Boost Medical School Prep With Undergrad Courses in Other Fields 2015-08-18T04:00:00Z The Advocate, Baton Rouge, Louisiana, on state’s economic growth factors: Louisiana editorial roundup 2015-08-05T04:00:00Z The researchers went for a trial-and-error approach: they made some educated guesses and painstakingly tested different combinations of growth factors. The boom in mini stomachs, brains, breasts, kidneys and more 2015-07-28T04:00:00Z Excess amounts of RCAN1 lower the activity of nerve growth factor, the researchers observed. Genetic Abnormality May Explain Health Complications of Down Syndrome 2015-12-14T05:00:00Z These are a broader set of risk and growth factors beyond conventional financial metrics that investors are now increasingly taking into account in a systematic way in the investment process. Taking the ESG Process From Chaos to Clarity 2015-06-17T04:00:00Z And whereas growth factors, antibodies and other complex 'biological' drugs can be produced in vats by bioengineered cells, these are mostly limited to secreted molecules. Business: The billion-dollar biotech 2015-06-02T04:00:00Z They prepared these cells by growing them in media containing different combinations of growth factors and chemicals. Scientists stumble across unknown stem-cell type 2015-05-05T04:00:00Z For three years, they tried various combinations and timings of growth factors. The boom in mini stomachs, brains, breasts, kidneys and more 2015-07-28T04:00:00Z The final growth factor is the emerging advances in robotics, nanotechnology, genomics, artificial intelligence and ubiquitous connectivity, which are just hitting the new product lines of big corporations and the radar screens of venture capitalists. In The U.S., Private Equity Investors Find Rich Opportunities And Fierce Competition 2015-04-28T04:00:00Z “We may end up using the same fluid throughout the chip, but locally supplementing each compartment with distinct growth factors,” says Bhatia. Artificial organs: Honey, I shrunk the lungs : Nature : Nature Publishing Group 2015-03-24T04:00:00Z High speed Internet has remained the leading growth factor for companies such as Comcast and Time Warner Cable for quite some time now. Republicans Question FCC's Net Neutrality Rules 2015-03-24T04:00:00Z In previous research he used growth factors extracted from tumors to stimulate cells, but this is not appropriate for food. After first lab-grown burger, test-tube chicken is next on menu 2015-03-12T04:00:00Z It offers what she calls “the trilogy of tissue repair”: a thick clot that serves as a short-term scaffold, stem cells to generate new tissue and growth factors to guide that regeneration. Three Biotech Solutions for Knee Repair 2015-03-10T04:00:00Z In Kobren’s view, the most promising option involves infusing growth factors from patients’ own platelets to their scalps to help regenerate hair. Hair Loss: Not Just a Man's Issue 2015-03-02T05:00:00Z Fasting glucose was most enriched for pancreatic islet enhancer marks and insulin-like growth factors in placenta, consistent with their endocrine regulatory roles85, 86. Integrative analysis of 111 reference human epigenomes : Nature : Nature Publishing Group 2015-02-17T05:00:00Z The swelling, redness, and warmth are signs that your immune system is sending white blood cells, immune cell-stimulating growth factors, and nutrients to the affected areas. 13 Ways Inflammation Can Affect Your Health 2015-02-14T05:00:00Z To mimic the harsh conditions inside a large tumor, Dr. Archetti and his colleagues fed their cancer cells a meager diet with a scarce supply of growth factors. In the Way Cancer Cells Work Together, a Possible Tool for Their Demise 2015-01-29T05:00:00Z PRP is replete with growth factors and other substances that promote healing. Three Biotech Solutions for Knee Repair 2015-03-10T04:00:00Z The bacterial strains confined in the chambers will form colonies—thanks in part, the team suspects, to growth factors from neighboring organisms that cross the membranes. Microbe found in grassy field contains powerful antibiotic 2015-01-07T05:00:00Z The platelets, which release growth factors for tissue healing, are re-injected into the injured joints and muscles. Warriors’ Bogut out indefinitely after PRP therapy 2014-12-18T05:00:00Z For Cisco Systems, the primary growth factor is going to be in new technologies and new products. Cisco Systems Earnings Preview - The Balancing Act Continues 2014-11-12T05:00:00Z He suspects that the other cells produce a growth factor of their own, creating “a reciprocal cross-talk,” as he put it. In the Way Cancer Cells Work Together, a Possible Tool for Their Demise 2015-01-29T05:00:00Z When those growth factors are strong enough, he said, it's apparent that those neighborhoods are becoming something different from what they were in the past. Downtown L.A. real estate is drawing N.Y. investors' interest 2014-10-05T04:00:00Z By carefully adding growth factors, he coaxed the organoids into forming the front or the back of the cortex. Yoshiki Sasai (1962-2014) : Nature : Nature Publishing Group 2014-09-02T04:00:00Z For example, a single exon gene on the opposite strand and in the last intron of the early developmental growth factor spätzle encodes a 42-amino-acid protein that is highly conserved across all sequenced Drosophila species. Diversity and dynamics of the Drosophila transcriptome : Nature : Nature Publishing Group 2014-03-15T04:00:00Z By far the biggest issue Post will address in the next year is the growth factor problem, which is more or less a deal-maker or breaker for lab-grown meat. The Frankenburger Is Coming Sooner Than You Think Thanks to Google 2014-08-15T04:00:00Z As tumors rapidly develop, they outgrow their blood supply, and stores of nutrients and growth-stimulating chemicals, known as growth factors, run low. In the Way Cancer Cells Work Together, a Possible Tool for Their Demise 2015-01-29T05:00:00Z By adding nutrients and growth factors, scientists kept the brain-like tissue alive in an incubator for two months, at which point they experimented on it. Scientists Create 3D Model That Mimics Brain Function 2014-08-11T04:00:00Z Those stem cells were then used to create primitive neurons, which the researchers embedded into a special scaffold created with the help of proteins called growth factors. Scientists Inch Closer Toward Using Stem Cells for Spinal Injuries 2014-08-07T04:00:00Z The research team worked from a basis of follower growth factors that were made up of variables from social science, linguistics, computer-mediated communication, and network theory. These Are Twitter's Biggest Secrets 2014-07-29T04:00:00Z Doctors also told Ms Meena it was important the baby received mother's milk as it contained hormones and growth factors that would help him become stronger. India's growing breast milk banking network 2014-07-16T04:00:00Z If the cheaters became too numerous, they ran low on the donated growth factors and their growth became sluggish. In the Way Cancer Cells Work Together, a Possible Tool for Their Demise 2015-01-29T05:00:00Z The process creates a solution of concentrated platelets and growth factors that is injected into the injured area to promote healing. Platelet-rich plasma treatment is popular for sports injuries, whether it works or not The main problem with intravenous administration is that the blood–brain barrier limits the passage of growth factors into the brain, so higher drug doses are often needed, leading to unwanted side effects. Drug delivery: Brain food : Nature : Nature Publishing Group 2014-06-24T04:00:00Z Other benefits include the release of nerve growth factors that keep neural connections healthy and functioning properly. The Surprising Key to Better Grades 2014-06-19T04:00:00Z One reason is that it appears to trigger the production of a growth factor, IGF-I, which is linked to cancer cell proliferation. Why Meat And Protein Are Not The Same 2014-06-15T04:00:00Z Add to those improved valuations the underlying growth factors plus the recent collision of technical indicators, and the stock market appeared to be at a tipping point. Fed's Warnings Launch Next Bull Market Leg 2014-06-06T04:00:00Z He objected to the removal of the automatic growth factor, citing increasing retirement costs for school districts. $3.6B school funding plan receives final passage 2014-05-30T04:00:00Z Suspended within the gel are two cellular growth factors, both neatly encapsulated in polymer shells that control the timing of their release. Drug delivery: Brain food : Nature : Nature Publishing Group 2014-06-24T04:00:00Z A new study finds that shining a low-power laser on damaged rat teeth activates molecular growth factors already present in the tissue. Laser Light Coaxes Damaged Rodent Tooth Repair 2014-05-28T04:00:00Z The drug specifically targets the "growth factor" proteins that cause lung tissue to stiffen and scar. 2 Drugs Offer Hope for Fatal Lung Disease 2014-05-18T04:00:00Z Researchers extract these cells and grow them in the lab, where they are treated with the appropriate growth factors and other agents to develop into specific types of cells, like neurons, muscle, or insulin-producing cells. Researchers Clone Cells from Two Adult Men 2014-04-17T16:00:43Z All growth factors were purchased from R&D. Mouse liver repopulation with hepatocytes generated from human fibroblasts 2014-04-04T18:27:44.990Z Eylea was developed from technology that was originally used to find growth factors that would be used as brain drugs. Regeneron Chief Leonard Schleifer Becomes A Billionaire After 25 Year Search For New Drugs 2014-02-25T21:20:00Z These growth factors cue stem cells to generate dentin, the bone-like substance that teeth are mostly made of. Laser Light Coaxes Damaged Rodent Tooth Repair 2014-05-28T04:00:00Z Later, recovery of endothelial Angiopoetin-2 expression facilitates angiogenesis in the regenerating liver in a vascular endothelial growth factor receptor 2–dependent manner. [Report] Endothelial Cell-Derived Angiopoietin-2 Controls Liver Regeneration as a Spatiotemporal Rheostat 2014-01-23T19:26:26.766Z It included peptides and female fertility drugs to supplement testosterone, human growth hormone and an insulin-like growth factor. Anti-doping expert says Alex Rodriguez used ‘potent cocktail of sophisticated PEDs’ 2014-01-15T05:09:54Z These tumor-associated macrophages also supply growth factors to cancer cells, to enable them to divide and grow; cancer cells reciprocally stimulate the macrophages by producing their favorite growth factor, known as Colony Stimulating Factor. The Hallmarks of Cancer 6: Tissue Invasion and Metastasis 2013-10-30T23:15:03.320Z The human body is a thriving biological metropolis of cells, growth factors, hormones, enzymes, nutrients, waste products and more. The Nobel Prize Winners Explained 2013-10-07T23:05:21Z Regional differences in selective pressures such as hypoxia, acidity and the presence of growth factors exist within a tumour and actively shape its development. Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z Binding of growth factor to the receptor binding site activates the kinase domain on the interior end of the receptor protein. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z Height is associated with increased milk intake in childhood, and higher levels of insulinlike growth factor, which promotes cell growth and inhibits programmed cell death, the authors noted. Cancer risk in women increases with height, study finds 2013-07-26T00:04:11Z Instead, say scientists, the association between height and cancer may help guide researchers to study hormones and growth factors that influence height and may also play a role in cancer. Well: Cancer Risk Increases With Height 2013-07-25T18:37:23Z But urging them to become functional, beating cardiomyocytes requires more than just oxygenated media and growth factors. Tissue engineering: How to build a heart 2013-07-03T17:20:24.187Z One possible reason: increased amounts of growth factor in obese people may promote tumor development. Well: A Label Calls Attention to Obesity 2013-07-01T04:01:23Z For example, one of the key downstream components of the growth factor signaling pathway is a protein known as Ras. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z But the stroma bathes the cells in growth factors and chemical signals that keep them in a dormant phase resistant to chemotherapy. Stem cells: Bad seeds 2013-06-26T17:20:57.320Z The long-term effects of deliberately inducing genetic manipulations on these growth factors aren’t known. The Man of Steel, Myostatin, and Super-Strength 2013-06-14T13:45:00.470Z On the other hand, loneliness may result in “a lack of sensory and cognitive stimulation,” which in turn reduces levels of nerve growth factors in the brain and may contribute to dementia. Personal Health: Shaking Off Loneliness 2013-05-13T18:55:29Z The drugs, known as leukocyte growth factors, will be the subject of a Friday meeting of an advisory committee to the U.S. Drugs from Amgen, others assessed by FDA as radiation treatments 2013-05-01T20:21:52Z Gleevec, used as treatment for chronic myelogenous leukemia and Herceptin, for the treatment of breast cancer, both inhibit specific components of growth factor response pathways to starve the cancer of this signal. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z In addition, a third type of cancer, called HER2-positive, produces too much of a protein called human epidermal growth factor receptor 2; it may be treatable with a targeted immunotherapy called Herceptin. Our Feel-Good War on Breast Cancer 2013-04-27T01:21:08Z Assessing these variables—including expression system, cell culture, fermentation, and various media components such as growth factors—is costly and time intensive if done individually. [Business Office Feature] Science Webinar Series: Advances in Protein Expression: High Throughput Tools for Improving Analysis 2013-04-18T17:56:49.430Z Normal full-term babies produce enough growth factors on their own to prevent diseases like ROP. UPDATE 1-Shire boosts rare diseases business by buying Premacure 2013-03-12T12:46:04Z Would human astrocytes maintain their unique properties inside the mouse brain where the cellular environment and mix of growth factors are different from those in the human brain? Human Brain Cells Make Mice Smart 2013-03-07T17:45:00.740Z All growth factors exert their effects by binding to a receptor. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z The three-times major winner said he was unaware the deer-antler spray, which he has been using for a couple of months, contained an insulin-like growth factor that is banned by the U.S. circuit. O'Meara calls for Singh ban over controversial spray use 2013-01-31T11:20:22Z The spray includes small amounts of a substance, insulin-like growth factor, banned by the NFL and other pro leagues, the magazine reported in an online story. Super Bowl XLVII: Ravens’ Ray Lewis endures the media day circus 2013-01-30T02:45:21Z "We believe a lot in growth factor treatment and plasma platelet treatments," Villas-Boas said. Tottenham in market for striker while Jermain Defoe nurses muscle tear 2013-01-29T22:30:04Z Receptors are proteins that are usually located on the external surface of the cell membrane; they provide specific recognition sites for messenger substances such as hormones, neurotransmitters and growth factors. The Nerve-Growth Factor: A New Tool for Manipulating Neurons 2013-01-03T11:15:00.190Z The binding of the growth factor to its specific receptor triggers a phosphorylation reaction inside the cell. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z One, called epidural growth factor and discovered by Dr. Cohen, plays a central role in ; in part by studying its behavior, scientists developed drugs to combat the abnormal growth. Dr. Rita Levi-Montalcini, a Revolutionary in the Study of the Brain, Dies at 103 2012-12-30T18:44:12Z There she discovered nerve growth factor, which regulates the growth of cells. Italy's Rita Levi-Montalcini dies 2012-12-30T18:51:30Z She is studying the role of nerve growth factor in the immune and endocrine systems. Finding the Good in the Bad: A Profile of Rita Levi-Montalcini 2012-12-30T17:45:00.203Z Like many anti-aging doctors, he diagnoses patients by testing for a blood component called insulin growth factor, which is indirectly tied to HGH. AP IMPACT: Big Pharma cashes in on HGH abuse 2012-12-21T11:02:11Z This liberation from being dependent on externally supplied growth factors removes a very critical checkpoint on the path towards cancer. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z If the skin is infected or wounded, the inflammatory response prompts immune cells to produce growth factors that promote both keratinocyte cell division and wound closure. Immunology: A many layered thing 2012-12-19T18:20:51.857Z Senescent cells secrete a variety of signalling molecules such as cytokines and chemokines; proteins such as growth factors; and enzymes such as proteases. Stem cells: Repeat to fade 2012-12-06T12:21:18.613Z In spite of the hardship—or perhaps, as Levi-Montalcini sees it, because of the adversity—it was during this time that she laid the groundwork for her later investigation of nerve growth factor. Finding the Good in the Bad: A Profile of Rita Levi-Montalcini 2012-12-30T17:45:00.203Z Meditation can improve blood flow, reduce stress, improve concentration and attention, enhance growth factors and reduce isolation. Ask an Expert: Ask and Expert About Alzheimer’s, Part 3 2012-11-21T17:21:55Z Since cancer cells hijack normal growth factor response pathways to become self sufficient, it is logical for us to target these errant pathways specifically. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z He threw out the serum usually added to growing embryonic stem cells, which contains a brew of uncharacterized growth factors and other signalling molecules. Tissue engineering: The brainmaker 2012-08-22T17:20:37.893Z To Adams's surprise, the mystery substance turned out to be a protein that's crucial to the development and survival of sensory neurons: neural growth factor, or NGF. Semen's Secret Ingredient 2012-08-20T20:04:00Z Her discovery of nerve growth factor led to a new understanding of the development and differentiation of the nervous system. Finding the Good in the Bad: A Profile of Rita Levi-Montalcini 2012-12-30T17:45:00.203Z An alternative technique is to deliver a protein called vascular endothelial growth factor, or VEGF, to promote blood-vessel growth in the heart. Nanotechnology Holds Promise for Heart Patients 2012-08-08T18:25:00Z Finally, there are alterations further downstream of the signaling pathway, so that the requirement for growth factor and receptor are both bypassed. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z Sasai found that balls left entirely alone give rise to cells like those in the developing brain region called the hypothalamus, but those given just a whiff of growth factors start differentiating into cerebral-cortex cells. Tissue engineering: The brainmaker 2012-08-22T17:20:37.893Z Erbitux blocks receptors to a different protein, called epidermal growth factor. FDA approves Sanofi/Regeneron colon cancer drug 2012-08-03T22:20:22Z Once the condition is identified, a person can be treated with blood transfusions or injections of a synthetic growth factor, which can help keep the illness at bay for a while. Nora Ephron’s Leukemia Was an Uncommon and Complicated Type 2012-06-28T04:14:31Z Colostrum works because it contains growth factors designed to strengthen the gut lining. How does colostrum help athletes? 2012-06-24T20:00:02Z Before I explain how growth signals are intimately involved in the development of cancer, it is necessary to define and understand what growth factors are, and explain how they control normal cellular behavior. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z All it took to grow a retina, it turned out, were a few tweaks, such as a reduction in the concentration of growth factors and the addition of a standard cell-culture ingredient called Matrigel. Tissue engineering: The brainmaker 2012-08-22T17:20:37.893Z Cancer occurs through genetic changes in cells allowing tumor growth factor receptors which activate various pathways, including a protein known as MEK. Glaxo melanoma drugs beat chemo in pivotal trials 2012-06-04T08:36:34Z One test measured growth hormone directly, and the other measured one of the downstream products of growth hormone, a blood chemical known as insulinlike growth factor, or I.G.F. Well: Dr. Lisa Sanders on Diagnosis 2012-05-04T16:34:12Z And there’s the ecological transition, which is a growth factor. Op-Ed Contributor: Pinning Down the Master of Evasion 2012-05-02T12:21:26Z The assortment of growth factors in this microenvironment is the most important aspect regulating the behavior of that cell. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z Once I combined my work with a colleague's, a bigger story emerged of how growth factors help to control how human embryonic stem cells differentiate into, say, bone marrow or skin. Turning point: Sean Bendall 2012-03-16T14:50:49.920Z Then we use growth factors to turn the cells into mesenchymal cells, an intermediate stage in the transformation to bone, cartilage and fat. Stem Cells: Flexible friends 2012-02-29T18:21:27.080Z In addition to secondary mutations and gene amplification, we also identified aberrant activation of other kinases including marked amplification of KIT and increased autophosphorylation of epidermal growth factor receptor in drug-resistant tumors from patients. [Research Articles] Mechanisms of Acquired Crizotinib Resistance in ALK-Rearranged Lung Cancers 2012-02-08T20:55:12.513Z Their blood also was tested for changes in brain-derived neurotropic growth factor, which encourages the health and growth of nerve cells. Exergaming may offer older people cognitive benefits 2012-01-23T18:14:04Z Even normal cells growing on a petri dish need growth factors supplied from animal serum to divide; if not they enter a dormant state and eventually die. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z RPE cells lie at the back of the eye and bathe the retina's rods and cones in substances called growth factors. First patients shown to improve with embryonic stem cells 2012-01-23T20:25:32Z They also had more VEGF, a growth factor whose functions include stimulating new blood vessel development. Stem Cells Build a Better Rat Penis 2012-01-23T20:02:00Z Using a similar approach, several studies in the 1990s and early 2000s showed that when myeloma binds to various neighbours, it spurs them to produce growth factors that benefit the cancer cell. Microenvironment: Neighbourhood watch 2011-12-14T18:21:10.780Z When, in the mid-1990s, several research groups developed procedures for turning mouse ES cells into heart cells using a cocktail of growth factors, Brüstle adapted the method to generate neural cells. Stem cells: The cell division 2011-12-14T18:20:32.107Z Additionally in some tumors, the growth factor receptor is structurally altered, sometimes lacking the regulatory regions, which results in the switch being permanently stuck at ‘on’. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z He believes that the transplanted RPE cells both bathed the deteriorating rods and cones in nourishing growth factors and gobbled up fragments of dead rods and cones, keeping the retinal environment healthier for the survivors. First patients shown to improve with embryonic stem cells 2012-01-23T20:25:32Z Their intraocular implant consists of human cells genetically modified to secrete a nerve growth factor they say is capable of rescuing and protecting dying photoreceptors. Electric Eye: Retina Implant Research Expands in Europe, Seeks FDA Approval in U.S. 2011-12-12T12:15:00.287Z And despite being termed senescent, the cells are very active: They convert themselves into factories that churn out 100 different kinds of growth factors, along with cytokines, the inflammatory agents that stimulate the immune system. In Body?s Shield Against Cancer, a Culprit in Aging May Lurk 2011-11-21T19:46:51Z Regeneron first focused on nerve growth factors to treat neurological illnesses like Lou Gehrig’s disease. Eylea, a Vision Drug, Wins Long-Sought Approval 2011-11-21T01:33:42Z Image credit: Gizmag It is impossible to talk about growth factors and cancer without going over some of the basics of cell signaling. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z He hopes that, over time, new technology will allow much lower doses of the drug to be used in combination with other growth factors or agents. Medtronic's Infuse sales drop seen worsening 2011-11-07T20:53:05Z “Changing demographics and the willingness to spend more for quality at convenience stores are major growth factors,” Takeshi Niinami, president of Lawson, the country’s second- biggest chain, said in an interview. Lawson Stores Thrive in Economy That Hammers Japan Inc.: Retail 2011-10-20T23:51:06Z The tumor cells lacked receptors for estrogen and progesterone that are associated with more curable cancers, but the cells carried receptors for HER-2/neu, a growth factor associated with aggressive disease. Personal Health: A Doctor?s Story of Survival and Transformation 2011-10-10T16:29:34Z In 2005, the Food and Drug Administration approved erlotinib, a drug that specifically targets growth factors found on cancer cells, for the treatment of patients with advanced pancreatic cancer who are receiving chemotherapy. Pancreatic Cancer: Steve Jobs' Battle 2011-10-06T06:06:32Z Normally, growth factors are made by one type of cell in order to act on another type of cell. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z Blood contains platelets that secrete growth factors that, in turn, can help tissue heal. As Sports Medicine Surges, Hope and Hype Outpace Proven Treatments 2011-09-05T02:25:21Z The researchers also found that the precursor fat cells were producing a platelet-derived growth factor — at 100 times the level of surrounding cells — that appeared to be kick-starting the follicles to grow hair. A Stem Cell Technique to Reverse Baldness? 2011-09-02T12:31:06Z From there, the concentrated platelets are then re-injected into the area where they release regenerating growth factors. Banks out while receiving PRP treatments 2011-08-21T20:07:39Z Immune system cells, maneuvered into behaving as if they were healing a wound, emit growth factors that embolden the tumor and stimulate angiogenesis, the generation of new blood vessels. Cancer?s Secrets Come Into Sharper Focus 2011-08-15T17:02:05Z This means that the cancer cell becomes hyper-responsive to ambient levels of growth factor that would normally not be enough to trigger cell division. Hallmarks of Cancer 1: Self-Sufficiency in Growth Signals 2013-09-18T13:15:00.663Z The problem may be that growth factors released from platelets need cells that can respond. As Sports Medicine Surges, Hope and Hype Outpace Proven Treatments 2011-09-05T02:25:21Z I believe mobile is far and away the next big growth factor in our industry. Technology versus the regulators 2011-08-03T23:02:07Z His team is also developing versions of the passport to detect steroid and growth-hormone abuse by charting changes in the urine or blood levels of compounds such as testosterone and insulin-like growth factor-1. New Anti-Doping Test Looks for Biochemical Changes over Time 2011-07-15T21:45:00.253Z The strongest response was to cells made by incorporating genes for certain growth factors into the DNA of the skin cells. Versatile Stem Cells Suffer Body Blow in a Study 2011-05-13T17:01:32Z The cell types needed for such devices are becoming more accessible, as are the growth factors and extracellular-matrix proteins needed to keep the cells healthy. Tissue models: A Living system on a chip 2011-03-30T17:21:20.057Z To that, they add a soup of growth factors that nourish the cells and encourage them to multiply into large quantities. Scientists grow viable urethras from boys' cells 2011-03-07T23:34:40Z Perhaps most importantly, the strategy decreases levels of a hormone known as insulin-like growth factor 1. Animals Aging Well 2011-03-02T15:07:00Z The study raises new questions about what besides estrogen drives tumors, suggesting a possible role for other growth factors or inflammation, Amy Trentham-Dietz of the University of Wisconsin said in a statement. Being too fat raises risk of deadly breast cancer: study 2011-03-01T23:52:38Z The cells were mixed with growth factors to make them multiply and then infused back into the patients. Gene therapy raises hope for a future AIDS cure 2011-02-28T20:01:20Z “Cells need a third plane to express the extracellular-matrix proteins and growth factors that they would express in the body,” says Applegate. Tissue models: A Living system on a chip 2011-03-30T17:21:20.057Z The drug, bevacizumab, is used against some cancers because it inhibits manufacture of a protein called vascular endothelial growth factor, or VEGF, that drives vessel growth. Saving Preemies' Vision 2011-02-17T15:33:00Z However, to be effective these growth factors must be retained at the ischemic site so as to reduce systemic side effects and also to allow for adequate time for new blood vessel formation. [Editors' Choice] Going With the Flow 2011-02-02T19:55:16.327Z Patients are usually treated with chemotherapy because the cancer does not respond to hormone-based drugs like tamoxifen, or drugs that target epidermal growth factors like Herceptin. Sanofi-Aventis says cancer drug has little effect 2011-01-28T15:55:59Z But in the end, the lower concentration of platelets and growth factors in the whole blood was better. Well: Phys Ed: Does Platelet-Rich Plasma Therapy Really Work? 2011-01-26T05:01:45Z "This compound traps the growth factor and renders it ineffective." Bayer to test drug to treat eye disease in Asia 2011-01-18T11:38:53Z The receptors thus join a family known as “dependence receptors” because in their presence, a cell is addicted to the presence of growth factor in order to prevent the proapoptotic effect of the unliganded receptor. Editors' Choice 2011-01-13T19:25:02.660Z These results highlight the potential of sustained and targeted growth factor delivery to stimulate blood vessel formation as a treatment for coronary artery disease. [Editors' Choice] Going With the Flow 2011-02-02T19:55:16.327Z "The recovery is becoming more sustainable and less dependent on temporary growth factors, particularly inventories," said Harm Bandholz, chief U.S. economist at UniCredit Research in New York. Payrolls seen hitting seven-month high 2011-01-07T05:18:18Z Regeneron Pharmaceuticals Inc. of Tarrytown, New York, said yesterday the FDA had halted trials of the company’s treatment in the class known as anti- nerve growth factors. J&J, AstraZeneca Halt Pain Drug Tests on Bone-Damage Concerns 2010-12-28T01:30:36Z Instead, he posits, the replacement cells release growth factors and wrap around new blood vessels, stabilizing them. Stem cells in fat may help repair damaged hearts 2010-11-22T17:38:00Z Other researchers also found blood levels of nerve growth factor, or NGF, also increased. Falling in Love Is 'More Scientific Than You Think' 2010-10-26T15:00:00Z Government spending is becoming an increasingly important growth factor in Britain, too. Cities hold key to healthier GDP 2010-10-24T19:05:00Z The Intuit report also suggests that as technology continues to advance, emerging markets will become an important growth factor in the economy. A Glimpse Into the Future 2010-10-13T15:53:00Z In their legs, genes were being expressed that activated growth factors that, in turn, increased levels of ‘‘important enzymes associated with cell defense’’ and ‘‘adaptation to exercise,’’ the researchers wrote. Phys Ed: Free the Free Radicals 2010-10-06T04:01:00Z The Celldex Therapeutics Inc vaccine works by targeting a mutation in a gene called the epidermal growth factor receptor, which fuels cancer growth. Developing brain cancer vaccine doubles survival 2010-10-04T20:16:00Z At Columbia University, researchers reported this summer they were able to regenerate rabbit joints inside the animals using bio-scaffolds treated with a specific growth factor. Medical: In future, our cells may repair arteries, joints, limbs 2010-08-18T17:50:00Z Exercise increases the level of brain chemicals called growth factors that help make new brain cells and establish new connections between brain cells to help us learn. 5 Mind-Blowing Benefits of Exercise 2010-06-30T20:45:00Z These platelets contain proteins known as growth factors, which promote cell growth and, thus, are beneficial to areas that normally are slow to heal, such as tendons. Studies don't agree on whether blood treatment speeds healing 2010-04-26T16:04:00Z Those contain growth factors thought to accelerate tissue repair and regeneration. Kenyon Martin to return to Nuggets lineup vs Spurs 2010-04-10T19:45:00Z Epidermal growth factor receptor mutations are found in many other cancers, and the teams say the vaccine should be tested in other cancers as well. Developing brain cancer vaccine doubles survival 2010-10-04T20:16:00Z The risk of breast cancer, too, is about 16 percent lower among physically active women, perhaps because exercise reduces tissue exposure to insulin-like growth factor, a known cancer promoter. Personal Health: Even More Reasons to Get a Move On 2010-03-01T22:53:00Z Our present society allows almost unlimited exercise of the growth factor in individuals, regardless of how powerful it may be. The Colonists Underlying growth factors have included expansion in the key agricultural and mining sectors, a more favorable atmosphere for business initiative, a more realistic exchange rate, a moderate inflation rate, and continued support by international organizations. The 2001 CIA World Factbook Compared with upland oak, walnut exceeded it in almost all growth factors up to 70 years of age and then they were about the same. Northern Nut Growers Association Report of the Proceedings at the Forty-Second Annual Meeting Urbana, Illinois, August 28, 29 and 30, 1951 Intensive gardening is a strategy holding that yield per square foot is the supreme goal; it succeeds by optimizing as many growth factors as possible. Gardening Without Irrigation: or without much, anyway As a group, they possessed a growth factor forcing them beyond the confines of the culture in which they lived. The Colonists But the essence of colonization is a growth factor—of the kind you so very accurately described when Bonnie pushed you into digging up some insight on the matter. The Colonists It is so often associated with rebellion because rebellion is or has been, historically, necessary to the exercise of this growth factor. The Colonists The latter may or may not have a sufficiently high growth factor. The Colonists In the past, colonies have invariably failed when they consisted only of members fleeing from something, without possessing an adequate growth factor. The Colonists |
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