| 单词 | granulation |
| 例句 | The visit to the Victoria and Albert certainly had that effect, especially the jewelry rooms and one particular ancient gold Etruscan bowl decorated with an esoteric technique called granulation. Daniel Brush, Boundary-Defying Artist, Is Dead at 75 2022-12-28T05:00:00Z The arachnoid granulations are outpocketings of the arachnoid membrane into the dural sinuses so that CSF can be reabsorbed into the blood, along with the metabolic wastes. Anatomy and Physiology 2013-06-19T00:00:00Z When skin is tattooed, the healing process is called granulation. Tattoos without borders: the Ukrainian artist mapping migration 2019-05-26T04:00:00Z Add sugar, and mix until there is no longer granulation to the sugar. Union Saloon’s chocolate dessert is a piece of cake 2018-01-30T05:00:00Z The telescope also will let people one at a time view sunspots, prominences and granulations of the sun’s surface, Snyder said. Former teacher hopes to reunite with students for eclipse 2017-08-20T04:00:00Z The burning fuse then lights much larger granulations of gunpowder at the bottom of the firework. The chemistry behind a firework explosion 2015-07-03T04:00:00Z Angiogenesis, the growth of new blood vessels, results in vascularization of the new tissue known as granulation tissue. Anatomy and Physiology 2013-06-19T00:00:00Z Preventing or checking the process of healing, or granulation. Webster's Unabridged Dictionary 2012-03-24T02:00:23.513Z Janssen of Paris took photographs of the solar photosphere so highly magnified that the granulation or willow-leaf structure of the surface was clearly visible, and its variations traceable from hour to hour. Astronomy: The Science of the Heavenly Bodies 2012-03-17T02:01:02.630Z The floor of the ulcers covers itself with delicate granulations, which in course of time are converted into connective tissue. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z On reaching the surface the granulations which form this out-growth exude a fluid which is highly contagious. The Fijians A Study of the Decay of Custom 2011-12-30T03:00:25.917Z When a large amount of granulation tissue forms and capillaries disappear, a pale scar is often visible in the healed area. Anatomy and Physiology 2013-06-19T00:00:00Z Filling up; promoting granulation of wounds or ulcers. Webster's Unabridged Dictionary 2012-03-24T02:00:23.513Z Once the cervix is torn the raw surfaces become covered by granulations and later by cicatricial tissue, but as a rule they do not unite. Encyclopaedia Britannica, 11th Edition, Volume 12, Slice 7 "Gyantse" to "Hallel" 2011-12-26T03:00:11.613Z The sequel� of otitis media, such as granulations sprouting out from the drumhead, some of which may be of large size and are known as polypi, may require treatment by the aurist. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z Inflammation is said to terminate in resolution, effusion, adhesion, suppuration, ulceration, granulation, cicatrization, and mortification. The American Reformed Cattle Doctor 2011-11-14T03:00:19.813Z The arachnoid emerges into the dural sinuses as the arachnoid granulations, where the CSF is filtered back into the blood for drainage from the nervous system. Anatomy and Physiology 2013-06-19T00:00:00Z By giving the cion and stock two or three months in which to form granulations and cohesion, there would be more certainty of success. The Nut Culturist A Treatise on Propogation, Planting, and Cultivation of Nut Bearing Trees and Shrubs Adapted to the Climate of the United States 2011-11-12T03:00:31.793Z As is everywhere the case throughout the body, granulation tissue in the process of healing contracts and forms scars. Arteriosclerosis and Hypertension: with Chapters on Blood Pressure, 3rd Edition. 2011-10-11T02:01:07.890Z In the severest types of the disease gangrene results from the intensity of the dermatitis, and the loss of tissue which thus occurs is repaired by the processes of granulation and cicatrization. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z Unhealthy granulations may be kept down by touching them with burnt alum, or sprinkling on their surface powdered bloodroot. The American Reformed Cattle Doctor 2011-11-14T03:00:19.813Z The CSF is then reabsorbed into the blood at the arachnoid granulations, where the arachnoid membrane emerges into the dural sinuses. Anatomy and Physiology 2013-06-19T00:00:00Z But to get to this point where these techniques will work, you really need to clean up the wound, get rid of dead tissue, and get robust granulation tissue into the wound. Creepy-crawlies may help heal diabetes wounds 2011-09-23T21:14:18Z These rabbits became tuberculous; they died in a few weeks with tuberculous granulations in lungs and liver. The Pros and Cons of Vivisection 2011-08-23T02:00:31.033Z Under favorable sanitary conditions the deposit, which consists in the main of pus-cells, clears away and the surface heals by granulation. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z This granulation leaves clots on the slab which are fatal to good work: whenever they are seen, the roller must be cleaned at once. Finger Prints 2011-08-07T02:00:07.827Z From the arachnoid granulations, CSF is reabsorbed into the blood, removing the waste from the privileged central nervous tissue. Anatomy and Physiology 2013-06-19T00:00:00Z The granulated surface of the paper, causing similar granulations in the touches on the ground, gives the character of a chalk drawing. The New Gresham Encyclopedia Volume 4, Part 2: Ebert to Estremadura 2011-04-14T02:00:56.200Z If too much acid is used it prevents the sugar advancing to the caramel stage, and also may cause granulation. The Century Cook Book 2011-01-04T03:01:10.367Z Meantime, the retraction of the uterus, the closure of the sinuses, and the formation upon the wounded surfaces of protecting granulations, all act as natural barriers to the penetration of poison-germs. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z After cleaning the plate, you proceed with the weaker solutions in the same way, the weakest giving the finest granulation for skies, distances, &c. Encyclopaedia Britannica, 11th Edition, Volume 2, Slice 3 "Apollodorus" to "Aral" Before the basal stem cells of the stratum basale can recreate the epidermis, fibroblasts mobilize and divide rapidly to repair the damaged tissue by collagen deposition, forming granulation tissue. Anatomy and Physiology 2013-06-19T00:00:00Z The same current is also rendered visible in the stems themselves by the motion of the granulations and gas bubbles in the interior of the osmotic cells. The Mechanism of Life One of the most common diseases of the eye is trachoma, often called “granular lids,” because the inner surface of the lid seems to be covered with little granulations. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 1 "Bisharin" to "Bohea" If, after a time, the granulations become flabby, Peruvian balsam or iodoform should be introduced into the sac at each change of the dressing. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z Thus it will be seen that the process of granulation with reference to its fineness is determined by the rapidity of evaporation. Nature's Miracles, Volume 1 Familiar Talks on Science—World-Building and Life. Earth, Air and Water. Specimens occur in which there is a slight granulation in the centre of the cap, but they are rare. Student's Hand-book of Mushrooms of America, Edible and Poisonous The granulations have agglomerated at the centre of the drops. The Mechanism of Life The granulation and crystallization is effected in large flat pans. History of Cuba; or, Notes of a Traveller in the Tropics Being a Political, Historical, and Statistical Account of the Island, from its First Discovery to the Present Time K�ster57 called attention to the regularity of the occurrence of miliary tubercles in the fungous granulations of the inflamed joints of scrofulous and tuberculous individuals. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z I put my fist against my forehead and heard the words echoing there emptily; "laceration ... primary efflusion ... serum and lymph ... granulation tissue...." The Planet Savers Even a simple inorganic crystal does not spring ready formed from its solvent, but first passes through phases of granulation and striation comparable with those which characterise the beginnings of vital growth. God and the World A Survey of Thought These artificial cells have heterogeneous cell-contents, and produce in their interior granulations which are disposed in a regular order. The Mechanism of Life The ulcers have a hemorrhagic border, a depressed suppurating surface, and contain a brownish or yellowish colored d�bris, which is soon replaced by granulation tissue. Special Report on Diseases of Cattle The granulations, if previously healthy, may soon slough. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z The granulation and crystallization are effected in large flat pans, or now more commonly by centrifugal machines, rotating at great speed. Due South or Cuba Past and Present And this conclusion is strengthened by comparison with the behaviour of the mast cells, which are related to the eosinophils in many points, and only differ from them essentially in the nature of their granulation. Histology of the Blood Normal and Pathological These spherical granulations united after a time to form crystals. The Mechanism of Life Afterwards antiseptic injections may be needed to stimulate healthy granulation and to prevent septic infection of the ocular membranes. Special Report on Diseases of Cattle The granulations, when previously healthy, soon slough, and venous oozing sometimes takes place. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z A masseuse told me she could effect no permanent improvement as there was granulation of the joints and a lesion. The Practice of Autosuggestion The fixation is complete in one minute, and the granulations can be demonstrated. Histology of the Blood Normal and Pathological In such cases the consequences must be the same, viz. granulation and segmentation. The Mechanism of Life The wound in the soft tissue should be kept open until the cavity in the bone has filled with granulation tissue. Special Report on Diseases of Cattle Ordinarily, where the pus is evacuated by spontaneous rupture or by incision the abscess heals quickly by granulation, leaving the gland enlarged and indurated for some time. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z Those of the vena portæ spread around the acini, or granulations of the liver; and 4. North American Medical and Surgical Journal, Vol. 2, No. 3, July, 1826 The best known example is the eosin-aurantia-nigrosin mixture, in which the hæmoglobin takes on an orange, the nuclei a black, and the acidophil granulations a red hue. Histology of the Blood Normal and Pathological In 1839, Link obtained spherical granulations by the precipitation of calcic or plumbic solutions by potash, soda, or carbonic acid. The Mechanism of Life Methods of healing.—Technically these may be divided into a number of distinct processes, but practically we may speak of them as two only, namely, by primary union, or adhesion, and by granulation. Special Report on Diseases of Cattle But neither the eyes, alas, nor the purses of our two emigrants are conformable to the Law; the former are filled with granulations of trachoma, the latter have been emptied by the sharpers of Marseilles. The Book of Khalid During granulation, the dough must be prevented from sticking, by using a little of the dry compound powder. The Cook and Housekeeper's Complete and Universal Dictionary; Including a System of Modern Cookery, in all Its Various Branches, Adapted to the Use of Private Families Nuclei are blue, hæmoglobin red, neutrophil granulation violet, acidophil pure red, mast cell granulation deep blue, forming one of the most beautiful microscopic pictures. Histology of the Blood Normal and Pathological On either side of the residue of the nucleus there appears a concentration of plasma, thus forming two perfectly regular star-like figures, whose rays are straight lines of granulations. The Mechanism of Life The second method of healing, namely, by granulation, which is, however, the manner in which most wounds in animals heal, takes much longer. Special Report on Diseases of Cattle The first point to consider in filtration is the dimensions of the filter bag, or container of the ground coffee, in relation to the quantity of coffee used and the granulation of same. All About Coffee This mode of granulation, though tedious, is the only one to be used for so small a quantity, for the sake of experiment. The Cook and Housekeeper's Complete and Universal Dictionary; Including a System of Modern Cookery, in all Its Various Branches, Adapted to the Use of Private Families The nuclei are greenish, the red blood corpuscles orange, the acidophil granulation copper red, the neutrophil violet. Histology of the Blood Normal and Pathological The sigmoid sinus is then exposed, and after any granulation tissue or pus that may be in the groove has been cleared away, the sinus is opened and the thrombus removed. Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. It is their magnificent opaque white granulations which, seen through the transparent skin, form the snow-white stripes in the live Spider. The Glow-Worm and Other Beetles The coarser the granulation the longer it is necessary to let the grounds remain in contact with the boiling water. All About Coffee She sought what she had seen fortune-tellers find in the granulations and the almost imperceptible traces left by the coffee as it trickled away. Germinie Lacerteux It is much to be recommended for good general preparations; it is indispensable in all cases where the study of the neutrophil granulations is concerned. Histology of the Blood Normal and Pathological If the incision is made early, this bone may soon be covered by granulations and recover its vitality; but if operation is delayed, it usually undergoes necrosis. Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. The granulations and their hardness are also objectionable, and if ground up too small, contraction to a greater degree takes place, and the repairer's object is defeated. The Repairing & Restoration of Violins 'The Strad' Library, No. XII. The degree of granulation also, of course, affects the rate of flow. All About Coffee The pulp is either white or red, and is full of little egg-shaped granulations. Travels in Peru, on the Coast, in the Sierra, Across the Cordilleras and the Andes, into the Primeval Forests The nuclei and the mast cell granulations stain deep blue, malaria plasmodia light sky blue, red corpuscles and eosinophil granules a fine red. Histology of the Blood Normal and Pathological The abscess should be laid open, all tuberculous granulations scraped away, and the sequestrum removed, with the aid of the chisel if it has not already become loose. Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. The external opening, which is through the centre of a corn-like formation, is small, and may or may not show the presence of granulations. Essentials of Diseases of the Skin Including the Syphilodermata Arranged in the Form of Questions and Answers Prepared Especially for Students of Medicine A chinaware sieve cannot be made as fine as a metal sieve and cannot of course hold very fine granulation as can cotton cloth. All About Coffee New granulation tissue would then find some degree of mechanical obstacle in the presence of a corky cell layer at first. Northern Nut Growers Association Report of the Proceedings at the Fifteenth Annual Meeting New York City, September 3, 4 and 5, 1924 The mast cell granulations are stained pure blue, the eosinophil red, the neutrophil in mixed colour. Histology of the Blood Normal and Pathological In cases of compound fracture, and in other conditions associated with necrosis of bone, masses of redundant granulation tissue growing from the soft parts outside the skull may simulate a hernia cerebri. Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. It is usually superficial, has thin, red, undermined edges of a violaceous color, and an irregular base with granulations covered scantily with pus. Essentials of Diseases of the Skin Including the Syphilodermata Arranged in the Form of Questions and Answers Prepared Especially for Students of Medicine The amount of ground coffee to use may vary from a heaping teaspoonful to a rounded tablespoonful for each cup of coffee desired, depending upon the granulation, the kind of apparatus used and individual taste. All About Coffee "Come, then! a hundred slaves, soldiers, a heap wherewith to buy——" Here the granulations of the cup's rim, detaching themselves, form a pearl necklace. The Temptation of St. Antony or A Revelation of the Soul The latter is free from granulations, feebly basophil, and in contrast to the protoplasm of the lymphocytes stains less deeply than the nucleus. Histology of the Blood Normal and Pathological The reparative material, consisting of granulation tissue in the process of conversion into bone, is called callus, on account of its hard and unyielding character. Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. Tracing paper is recommended instead of linen, which latter, on account of its thickness and granulation, gives less satisfactory results in regard to the transparency of the ground and the continuity of the lines. Photographic Reproduction Processes Unbleached muslin makes the best bag for this granulation. All About Coffee Here it is boiled till it is reduced to syrup, and then it is boiled again, until it is ready for granulation. The Land of the Kangaroo Adventures of Two Youths in a Journey through the Great Island Continent These are characterised by a coarse, round granulation, staining deeply with acid dyes, and similar in other respects to the polynuclear neutrophils. Histology of the Blood Normal and Pathological The presence of polypi and granulations, with pus oozing out from between them, and increasing after withdrawal of the probe, and the detection of carious bone are significant of ethmoidal suppuration. Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. In a majority of cases the process of cicatrization will take place, and the cavity fill up by granulation, the discharge, at first abundant, gradually diminishing and the wound closing, usually without leaving any mark. Special Report on Diseases of the Horse In that case, a portion of the gruel with which the animal is drenched escapes for a few days; but I always found that the wound healed by granulation, without any particular attention. Cattle and Their Diseases Embracing Their History and Breeds, Crossing and Breeding, And Feeding and Management; With the Diseases to which They are Subject, And The Remedies Best Adapted to their Cure Acini: granulations, like those on a blackberry: the terminal secreting tubes of glands. Explanation of Terms Used in Entomology Their intensely basophil granulation, of very irregular size and unequal distribution, must specially be mentioned. Histology of the Blood Normal and Pathological The surface of the ulcer is uneven, pale and flabby, and is covered with a yellowish-grey discharge, with here and there feeble granulations showing through. Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. If the wound is pale in color, the granulations transparent and glistening, the tincture of aloes, tincture of gentian, or the spirits of camphor may do best. Special Report on Diseases of the Horse The chief difficulty in grafting or budding the hickories is due to slow formation of callus and of granulation processes which carry on repair of wounds. Northern Nut Growers Association Report of the Proceedings at the Second Annual Meeting Ithaca, New York, December 14 and 15, 1911 A few days later this granulation tissue begins to contract and pull the lips of the wound together. Preventable Diseases The granulation possesses the further peculiarity, in that with the majority of basic dyes it stains, not in the pure colour of the dye, but metachromatically—most deeply with thionin. Histology of the Blood Normal and Pathological The tricuspid and mitral valves were thickened, and exhibiting minute granulations on their surface. An Investigation into the Nature of Black Phthisis or Ulceration Induced by Carbonaceous Accumulation in the Lungs of Coal Miners These openings are surrounded by a small mass of granulations which are elevated above the adjacent skin and bleed readily if handled. Special Report on Diseases of the Horse Antyllus performed an operation for aneurism, which consisted in laying open the sac, turning out the clots, securing the vessels above and below, and allowing the wound to heal by granulation. Outlines of Greek and Roman Medicine The clot is transformed into what we term granulation tissue and begins to organize. Preventable Diseases A fundamental distinction from the large mononuclear cells lies in the fact that the protoplasm exhibits a more or less numerous neutrophil granulation. Histology of the Blood Normal and Pathological This sequence was chiefly of prognostic significance as an indication of intra-cranial inflammation, usually of a chronic character, and affecting rather the lowly organised granulation tissue formed in the cavity than the brain itself. Surgical Experiences in South Africa, 1899-1900 Being Mainly a Clinical Study of the Nature and Effects of Injuries Produced by Bullets of Small Calibre When the granulations look red, dress the wound with oakum balls saturated in a weak solution of tincture of aloes or spirits of camphor and apply a roller bandage. Special Report on Diseases of the Horse In this way the approximate granulation of any grade of flour may be determined, and the granulation of an unknown sample be compared with that of a standard flour. Human Foods and Their Nutritive Value If the wound fails to heal immediately, a treatment calculated to encourage granulations should be undertaken. Old-Time Makers of Medicine The Story of The Students And Teachers of the Sciences Related to Medicine During the Middle Ages This granulation, which Ehrlich had previously found in the rabbit, is easily distinguishable from the true eosinophil, since it is much finer, and stains quite differently in eosine-aurantia-nigrosin mixtures. Histology of the Blood Normal and Pathological This bone, together with the middle finger, was removed, and healing took place by granulation slowly. Surgical Experiences in South Africa, 1899-1900 Being Mainly a Clinical Study of the Nature and Effects of Injuries Produced by Bullets of Small Calibre Healing then occurs by granulation or suppuration, which is termed healing by second intention. Special Report on Diseases of the Horse In determining the granulation of a flour, if there are any coarse or discolored particles of bran or dust, they should be noted, as it is an indication of poor milling. Human Foods and Their Nutritive Value This may be thin or serum-like, or it may be heavier, something like granulations. The Sagebrusher A Story of the West The true eosinophil granulation remains, on the other hand, quite unchanged under these conditions. Histology of the Blood Normal and Pathological The patient made an uneventful and uninterrupted recovery, the wound healing by granulation and leaving little weakness of the abdominal wall. Surgical Experiences in South Africa, 1899-1900 Being Mainly a Clinical Study of the Nature and Effects of Injuries Produced by Bullets of Small Calibre The sides of the wound become covered with granulation tissue which may fill the wound and sometimes overlap the lips, forming a fungoid growth called proud flesh. Special Report on Diseases of the Horse The commercial grade of a flour can be accurately determined from the color, granulation, absorption, gluten and ash content, and the quality of the bread. Human Foods and Their Nutritive Value The paraffin is waterproof and prevents evaporation from the scion, which otherwise is prone to dry out before granulation of the wound has taken place in the hickories, as in other species which callus slowly. Northern Nut Growers Association, Report Of The Proceedings At The Tenth Annual Meeting. Battle Creek, Michigan, December 9 and 10, 1919 In their general appearance, in the size of the cell and the granulation, they completely correspond to the eosinophil cell. Histology of the Blood Normal and Pathological Disturbed granulations result in bleeding which further hampers the operation; therefore, they should not be touched until ready to apply the forceps, unless it is impossible to study the presentation without disturbing them. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery Four or five days of irrigation will be sufficient, for granulations will then have formed and pus will remain on the outside if it forms. Special Report on Diseases of the Horse How does the granulation affect the physical properties of flour? Human Foods and Their Nutritive Value The system of granulation adopted by the Army differs from that of the Navy, as follows: All Through— All On— Mammoth 0.9 in. Ordnance Instructions for the United States Navy. 1866. Fourth edition. The only distinction between them consists in a chemical difference in the granulation. Histology of the Blood Normal and Pathological It remains in the lung, held in a bed of granulation tissue. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery An ulcer is a circumscribed area of necrosis occurring on the skin or mucous membrane and covered with granulation tissue. Special Report on Diseases of the Horse How is the granulation of flour approximately determined? Human Foods and Their Nutritive Value With regard to scars and their permanence, it will be remembered that scars occasioned by actual loss of substance, or by wounds healed by granulation, never disappear. Aids to Forensic Medicine and Toxicology The two granulations always show different shades in the triacid preparation as well; for the nigrosinophil cells stain a blacker hue. Histology of the Blood Normal and Pathological The stenotic tissue in cases of a few months' sojourn maybe composed of granulations, in which case axis-traction will safely withdraw it. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery The secretions of the ulcer should be washed off with antiseptic solutions and the formation of granulation tissues stimulated by antiseptic salves, such as carbolated vaseline, lead ointment, or by dressings of camphor. Special Report on Diseases of the Horse The granulation of the middlings is done after the impurities are removed, the object being first to separate as perfectly as possible the middlings from the branny portions of the kernel. Human Foods and Their Nutritive Value They were the granulation of bricks and mortar and earth mixed by the blasts of shell fire which crushed solids into dust and splintered splinters. My Second Year of the War It shews transitions in the blood, from large mononuclear to transitional and polynuclear forms, but is marked by the lack of any kind of granulation. Histology of the Blood Normal and Pathological The work is completed by cutting off the sac and either suturing the esophageal wound or touching it with the cautery, and allowing it to heal by granulation. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery The hairs over this part loosen and fall off, and in a short time the abscess opens, the contents escape, and the cavity gradually fills up—heals by granulations. Special Report on Diseases of the Horse Grades of Flour.—Flour is the purified, refined, and bolted product obtained by reduction and granulation of wheat during and after the removal of the branny portions of the wheat kernel. Human Foods and Their Nutritive Value It is chronic in character, and is distinguished by the development of raspberry-like tumors of granulation tissue on different parts of the body. Scientific American Supplement, No. 315, January 14, 1882 This is proved by the complete agreement in general morphological character, in staining properties of the protoplasm and nucleus, and from the absence of granulation. Histology of the Blood Normal and Pathological If the skin-wound heals before the fibrous union of the tracheal cartilages is complete, exuberant granulations are apt to form and occlude the trachea, perhaps necessitating a new tracheotomy for dyspnea. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery The surface of the resulting ulcers or abscess cavities soon fills up with exuberant granulations which protrude beyond the surface of the skin, giving it a fungoid appearance. Special Report on Diseases of the Horse The high grades are characterized by a lighter color, more elastic gluten, better granulation, and a smaller number of débris particles. Human Foods and Their Nutritive Value A more sluggish form than the preceding, distinguished by its larger size, its dense granulation, and by short, rounded pseudopodia, which, as in Amœba proteus, may come from any part of the body. Marine Protozoa from Woods Hole Bulletin of the United States Fish Commission 21:415-468, 1901 The kinds of special granulations so far investigated have the common property, that they stain in acid and neutral dyes respectively; they shew a much smaller affinity for the basic dyes. Histology of the Blood Normal and Pathological Aluminum becomes roughened by boiling and contact with secretions, and causes the formation of granulations which in time lead to stenosis. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery Diagnosis.—The diagnosis is based on the characteristic appearance of the ulcerations, which show exuberant granulation of a bright red color, inverted edges, and a thick, creamy, glutinous discharge. Special Report on Diseases of the Horse As fast as it evaporates, fresh sap is poured in until the syrup becomes thick, and then follows granulation, or, as the farmers call it, 'sugaring off.' The Story of a Summer Or, Journal Leaves from Chappaqua These latter appear on the surface of the granulations as small bluish islets which gradually increase in size, become of a greyish-white colour, and ultimately blend with one another and with the edges. Manual of Surgery Volume First: General Surgery. Sixth Edition. Ehrlich has been able by special differential staining to bring forward proof that the constitution of the granulation changes during the metamorphosis of the mononuclear to the polynuclear cells. Histology of the Blood Normal and Pathological Luetic ulcers commonly show a surrounding inflammatory areola, and they usually have thickened elevated edges, generally free from granulation tissue, with a pasty center not bleeding readily when sponged. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery These manifestations differentiate the disease from glanders, in which the ulcers are craterlike, do contain exuberant granulations, and the discharge is of a viscous, oily character. Special Report on Diseases of the Horse Take a little tallow and put it into a spoon, and heat it over a lamp until it becomes very hot; then pour it on the sore or granulation. Our Deportment Or the Manners, Conduct and Dress of the Most Refined Society When the disease begins in the bone, the marrow is converted into granulation tissue, which eats into the cartilage and separates it from the bone. Manual of Surgery Volume First: General Surgery. Sixth Edition. Arnold, explain this double staining of the eosinophil cells by the presence of eosinophil and mast cell granulation side by side. Histology of the Blood Normal and Pathological The fenestrum is, moreover, rarely so situated that air can pass through it; the fenestral edges act as a constant irritant to the wound, producing bleeding and granulation tissue. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery This is pulverized or granulated, the degree of granulation depending upon the size of the furnace. Scientific American Supplement, No. 508, September 26, 1885 Gunpowder they make in great quantities, but either from the injudicious proportion of the ingredients in the composition, or the imperfect granulation, it is very defective in strength. The History of Sumatra Containing An Account Of The Government, Laws, Customs And Manners Of The Native Inhabitants The disease spreads throughout the capsule and synovial membrane, which becomes diffusely thickened and infiltrated with granulation tissue which eats into and replaces the articular cartilage. Manual of Surgery Volume First: General Surgery. Sixth Edition. That this is certainly not the case is shewn by the fact that the "basophil" granulation of the eosinophil cells does not in metachromatic staining shew the metachromasia characteristic for the mast cells. Histology of the Blood Normal and Pathological Caution should be used as to removal of the granulations with which the abscess "cavity" is filled in chronic cases. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery This minimizes granulation of tissue, and there results less scar if the detached portions are kept near, even if not in contact with the proximal wound margins. Lameness of the Horse Veterinary Practitioners' Series, No. 1 Every particle of the flesh had sloughed off, and the leg began to heal not "by first intention" but by unhealthy granulations like excrescences. Memories A Record of Personal Experience and Adventure During Four Years of War Where the soft tissues are pressed against the edge of the nail, the skin gives way and there is the formation of exuberant granulations and of discharge which is sometimes fœtid. Manual of Surgery Volume First: General Surgery. Sixth Edition. Earlier observations, especially on the mast cells, led me to expect that these granulations, though they had long been inaccessible to chemical analysis, could be distinguished by their behaviour with certain stains. Histology of the Blood Normal and Pathological Erosion through of peri-bronchial or peri-tracheal lymph masses may be associated with granulation tissue, usually of pale color, but occasionally reddish; and sometimes oozing of blood is noticed. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery Where the divided parts of the tendon are maintained in fairly close and constant relation, granulation of tissue, sufficient to sustain weight takes place in from six weeks to three months. Lameness of the Horse Veterinary Practitioners' Series, No. 1 To a scientific eye, and under my instruction you shall get one, there is something delightful in witnessing the granulations. The Lost Hunter A Tale of Early Times Sooner or later the epidermis gives way in the centre, exposing a smooth raw surface devoid of granulations. Manual of Surgery Volume First: General Surgery. Sixth Edition. He then found red granulations almost exclusively, only the granules of the smooth musculature of the stomach were stained intensely blue. Histology of the Blood Normal and Pathological Later, granulation tissue and the formation of stricture further hide the object. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery When the wound has filled with granulation, a protective dressing is applied which is rendered water proof by the use of bandages covered with oil of tar. Lameness of the Horse Veterinary Practitioners' Series, No. 1 Gun-cotton, analysis of, 212. boiling, 64. complete series of, 52, 54. compressing, moulding, and packing, 67, 77, 78. dipping and steeping the cotton, 60. drying the cotton, 58. granulation of, 79. manufacture of, 57. Nitro-Explosives: A Practical Treatise The sequestrum is separated from the living bone by a clear zone which corresponds to the layer of granulations lining the cavity in which it lies. Manual of Surgery Volume First: General Surgery. Sixth Edition. The substance of the mast cell granulations is also crystalline in some species of animals. Histology of the Blood Normal and Pathological If it is a continuation from more extensive extra-esophageal tuberculous ulceration, pale cauliflower granulations may be present. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery If the synovitis or arthritis remains non-infected and the wound, traumatic or surgical, is not too large, healing by granulation occurs, and the discharge of synovia ceases. Lameness of the Horse Veterinary Practitioners' Series, No. 1 It then undergoes the processes of granulation, sifting, dusting, drying, and glazing. Nitro-Explosives: A Practical Treatise Sometimes the tuberculous granulation tissue spreads in the marrow, assuming the characters of a diffuse infiltration—diffuse tuberculous osteomyelitis. Manual of Surgery Volume First: General Surgery. Sixth Edition. The eosinophil granulation reaches its greatest size in the horse, where really gigantic examples are found. Histology of the Blood Normal and Pathological An ulcer surrounded by an inflammatory areola and the granulation tissue together illustrates the etiology of cicatricial tissue. Bronchoscopy and Esophagoscopy A Manual of Peroral Endoscopy and Laryngeal Surgery As the water boils, the camphor rises with the steam, and attaches itself as a sublimate to the stalks, under the form of granulations of a grey color. The Commercial Products of the Vegetable Kingdom Considered in Their Various Uses to Man and in Their Relation to the Arts and Manufactures; Forming a Practical Treatise & Handbook of Reference for the Colonist, Manufacturer, Merchant, and Consumer, on the Cultivation, Preparation for Shipment, and Commercial Value, &c. of the Various Substances Obtained From Trees and Plants, Entering into the Husbandry of Tropical and Sub-tropical Regions, &c. Even where there is no immediate contact, the proximity of such a mass gives rise to modifications of solidification, cohesion, granulation, and crystallization. COSMOS: A Sketch of the Physical Description of the Universe, Vol. 1 The bone is replaced by granulation tissue, and disappears, or part of it may become sclerosed and in time form a sequestrum. Manual of Surgery Volume First: General Surgery. Sixth Edition. In birds we recognise two oxyphil granulations, of which one is embedded in the cells in the crystalline, the other in the usual granular form. Histology of the Blood Normal and Pathological It was smooth, dark-grey, and clear; free from air, and free from surface lines; very hard, and suggesting the idea of coarse internal granulation. Ice-Caves of France and Switzerland On the other hand, a rightly fermented vat is easy to work; the froth, though abundant, vanishes whenever the granulations make their appearance. The Commercial Products of the Vegetable Kingdom Considered in Their Various Uses to Man and in Their Relation to the Arts and Manufactures; Forming a Practical Treatise & Handbook of Reference for the Colonist, Manufacturer, Merchant, and Consumer, on the Cultivation, Preparation for Shipment, and Commercial Value, &c. of the Various Substances Obtained From Trees and Plants, Entering into the Husbandry of Tropical and Sub-tropical Regions, &c. Face to face with ruin because of the failure of the indigo crop, he staked his all on the granulation of sugar. The Journal of Negro History, Volume 1, January 1916 After the tuberculous granulation tissue erupts through the cortex of the bone, it gives rise to a cold abscess or infects adjacent joints or tendon sheaths. Manual of Surgery Volume First: General Surgery. Sixth Edition. In the majority of the animals observed, he found too that the polynuclear cells contained neutrophil granules; in only one animal, the white mouse, did he find them, or granulations analogous to them, completely wanting. Histology of the Blood Normal and Pathological This is, of course, when the gun, cartridge case, primer, and projectile are adapted to the use of smokeless powder, and the granulation of the powder is adapted to them. Scientific American Supplement, No. 821, September 26, 1891 If large round granulations are formed, the beating is continued, in order to see if they will grow smaller. The Commercial Products of the Vegetable Kingdom Considered in Their Various Uses to Man and in Their Relation to the Arts and Manufactures; Forming a Practical Treatise & Handbook of Reference for the Colonist, Manufacturer, Merchant, and Consumer, on the Cultivation, Preparation for Shipment, and Commercial Value, &c. of the Various Substances Obtained From Trees and Plants, Entering into the Husbandry of Tropical and Sub-tropical Regions, &c. To prevent granulation, it often is advisable to add a pinch of cream of tartar, to the pound of sugar. The Story of Crisco Finally, the sequestrum lies loose in a cavity lined by tuberculous granulation tissue, and is readily identified in a radiogram. Manual of Surgery Volume First: General Surgery. Sixth Edition. The lymphocytes on the contrary, incapable of emigration, are almost totally devoid of specific granulations. Histology of the Blood Normal and Pathological Antonyms: meek, humble. proud flesh. granulation, fungus. provable, a. demonstrable. prove, v. verify, corroborate, substantiate, demonstrate. Putnam's Word Book Whenever the granulations become round, and begin to subside, and the liquor clears up, the beating must be discontinued. The Commercial Products of the Vegetable Kingdom Considered in Their Various Uses to Man and in Their Relation to the Arts and Manufactures; Forming a Practical Treatise & Handbook of Reference for the Colonist, Manufacturer, Merchant, and Consumer, on the Cultivation, Preparation for Shipment, and Commercial Value, &c. of the Various Substances Obtained From Trees and Plants, Entering into the Husbandry of Tropical and Sub-tropical Regions, &c. The task, now is to induce the granulation of a new one. Lippincott's Magazine of Popular Literature and Science Volume 17, No. 098, February, 1876 Changes in the Synovial Membrane.—In the majority of cases there is a diffuse thickening of the synovial membrane, due to the formation of granulation tissue, or of young connective tissue, in its substance. Manual of Surgery Volume First: General Surgery. Sixth Edition. A further indication that the granulations really are connected with a specific cell activity lies in the fact, that one cell bears but one specific granulation. Histology of the Blood Normal and Pathological Hexagonal areas with an acute angle above and below; bottom of area pyriform, surface covered with minute transparent granulations. Narrative of the Voyage of H.M.S. Rattlesnake, Commanded By the Late Captain Owen Stanley, R.N., F.R.S. Etc. During the Years 1846-1850. Including Discoveries and Surveys in New Guinea, the Louisiade Archipelago, Etc. to Which Is Added the Account of Mr. E.B. Kennedy's Expedition for the Exploration of the Cape York Peninsula. By John Macgillivray, F.R.G.S. Naturalist to the Expedition. — Volume 1 One is manifest; the sugar may be grained in the pan, and the granulation is completely under the control of the operator. The Commercial Products of the Vegetable Kingdom Considered in Their Various Uses to Man and in Their Relation to the Arts and Manufactures; Forming a Practical Treatise & Handbook of Reference for the Colonist, Manufacturer, Merchant, and Consumer, on the Cultivation, Preparation for Shipment, and Commercial Value, &c. of the Various Substances Obtained From Trees and Plants, Entering into the Husbandry of Tropical and Sub-tropical Regions, &c. Into what granulations might not our society have crumbled? The Last Leaf Observations, during Seventy-Five Years, of Men and Events in America and Europe The young bone is replaced by granulation tissue, so that large clear areas are seen with the X-rays. Manual of Surgery Volume First: General Surgery. Sixth Edition. The contrary assertions that neutrophil and eosinophil, or eosinophil and mast cell granulations occur in the same cell Ehrlich regards as unfounded, from extensive researches specially directed to this point. Histology of the Blood Normal and Pathological Cells biserial; opening oval, truncated above, and the upper margin recedent, with a spine on each side, the outer the longer surface of cell covered with transparent granulations. Narrative of the Voyage of H.M.S. Rattlesnake, Commanded By the Late Captain Owen Stanley, R.N., F.R.S. Etc. During the Years 1846-1850. Including Discoveries and Surveys in New Guinea, the Louisiade Archipelago, Etc. to Which Is Added the Account of Mr. E.B. Kennedy's Expedition for the Exploration of the Cape York Peninsula. By John Macgillivray, F.R.G.S. Naturalist to the Expedition. — Volume 1 The ramifications are lost in the periphery amid fine granulations that resemble spores. Scientific American Supplement, No. 481, March 21, 1885 I asked her to report to me in two or three days, and, on reporting, I found a healthy granulation presenting. Scientific American Supplement, No. 415, December 15, 1883 It may follow upon fibrous or cartilaginous ankylosis, or may result from the fusion of two articular surfaces which have lost their cartilage and become covered with granulations. Manual of Surgery Volume First: General Surgery. Sixth Edition. Doubtless other granulations have a more complicated constitution, and very often are a mixture of various chemical substances. Histology of the Blood Normal and Pathological Where a counter-opening is thus made it is found that it very readily closes with granulation tissue, and the purpose for which it was made defeated. Diseases of the Horse's Foot Preparations made from fragments of Sable and Lamore coal could not be made sufficiently thin to be transparent; the mass remained very opaque, and the clearest parts exhibited merely amorphous, irregular granulations. Scientific American Supplement, No. 481, March 21, 1885 Instead of healing, the broken vessels became blackish and healed slowly, leaving ulcers, granulations, and scars, and the gangrenous tendency of the skin increased. Anomalies and Curiosities of Medicine Sometimes the epidermis gives way, forming an ulcer with flabby granulations. Manual of Surgery Volume First: General Surgery. Sixth Edition. It should be mentioned that according to Barker the eosinophil granulations appear to contain iron. Histology of the Blood Normal and Pathological Their increase in size is due to the inflammatory absorption of the bony tissue forming them, and in the larger of them may be seen inflammatory granulation tissue surrounding the bloodvessels. Diseases of the Horse's Foot These granulations eventually fill the contracting cavity and obliterate it by forming interstitial scar-tissue. The Project Gutenberg Encyclopedia Volume 1 of 28 This extent is shown in Figure 228, taken five months after the accident, when the granulations had grown over the edge about an inch. Anomalies and Curiosities of Medicine The sheath itself is thickened by the growth of tuberculous granulation tissue. Manual of Surgery Volume First: General Surgery. Sixth Edition. In the first place it is occasionally seen that the mast cell granulation is dissolved within the cell, and diffuses in solution into the nucleus. Histology of the Blood Normal and Pathological Directly a healthy and pink-looking granulation is observed along the track of the iron, and the discharge therefrom takes on a thick and yellow appearance, the strength of the antiseptic solutions should be gradually diminished. Diseases of the Horse's Foot This lowly organized material is called granulation tissue, and exactly resembles the growth which covers the floor of an ulcer. The Project Gutenberg Encyclopedia Volume 1 of 28 There was little hemorrhage, and the wound was healed by granulation. Anomalies and Curiosities of Medicine In this process the coagulum only plays a passive rôle by forming a scaffolding on which the granulation tissue is built up. Manual of Surgery Volume First: General Surgery. Sixth Edition. How little adequate tinctorial differences by themselves are to settle the chemical identity of a granulation, is at once evident on consideration of the granules of other organs. Histology of the Blood Normal and Pathological One week after treatment the diseased surface was drier, and granulations were more healthy. Diseases of the Horse's Foot When evacuating an abscess it is often advisable to scrape away the lining of unhealthy granulations and to wash out the cavity with an antiseptic lotion. The Project Gutenberg Encyclopedia Volume 1 of 28 The protuberance will slough off and healthy granulations will spring up. The Dog The articular cartilages are destroyed, the ends of the bones are covered with granulations, extra-articular abscesses form, and complete osseous ankylosis results. Manual of Surgery Volume First: General Surgery. Sixth Edition. As shewn by the former they appear as polynuclear cells free from granules, since their granulation takes on no dye of the triacid mixture. Histology of the Blood Normal and Pathological The mouth of each fistula is generally filled with a mulberry-like granulation tissue, standing above the level of the skin, and bleeding easily if touched. Diseases of the Horse's Foot Healing by second intention is characterized by pus formation and granulation tissue. Common Diseases of Farm Animals In a little more than three weeks the wound had completely filled up with healthy granulations, and the dog was sent home to all appearance quite well. The Dog In moderately acute cases the tendon and its sheath become covered with granulations, which subsequently lead to the formation of adhesions; while in more acute cases the tendon sloughs. Manual of Surgery Volume First: General Surgery. Sixth Edition. The larva is distinguished from that of æsculana by having the minute granulations of the skin smooth, whereas in the latter each granule has a minute sharp point. 3d. Scientific American Supplement, No. 363, December 16, 1882 From it there is a discharge of pus, black in colour and offensive in smell, and, protruding from the opening, are excessive granulations of the remains of the sensitive sole. Diseases of the Horse's Foot This is termed excessive granulation or "proud flesh." Common Diseases of Farm Animals Fungous granulations spring from it, protrude through the lids, and the animal evidently suffers extreme torture. The Dog The tuberculous granulation tissue is liable to break down and lead to the formation of a cold abscess and sinuses, and in our experience is often associated with disease in an adjacent bone or joint. Manual of Surgery Volume First: General Surgery. Sixth Edition. If the whole tree is hewn down the trunk tries to repair the injury by producing small granulations of tissue between the wood and the bark, which gradually coalesce while becoming larger. Species and Varieties, Their Origin by Mutation The most serious complication arising from this method of treatment is one of excessive granulation of the sensitive sole. Diseases of the Horse's Foot This protects the surface of the wound until finally the destroyed tissue is replaced by the granulations, and the skin surface is restored. Common Diseases of Farm Animals He makes of the countenances of his foes a fry and of their bodies a comprehensive granulation. My Tropic Isle The carious process is preceded by the formation of granulation tissue in the marrow or periosteum, which eats away and replaces the bone in contact with it. Manual of Surgery Volume First: General Surgery. Sixth Edition. By slow evaporation, they make large crystals of salt; by quick boiling, small granulations. Life of Johnson, Volume 5 Tour to the Hebrides (1773) and Journey into North Wales (1774) Should the granulations become very exuberant, then the knife must be called to our aid, and the wound so made afterwards dressed with an astringent. Diseases of the Horse's Foot Abnormal granulation is not an uncommon form of healing in domestic animals. Common Diseases of Farm Animals This simple experiment illustrates the important fact that granulations have no inherent tendency to form pus, but do so only when subjected to preternatural stimulus. The Harvard Classics Volume 38 Scientific Papers (Physiology, Medicine, Surgery, Geology) The granulation tissue may undergo caseation and liquefaction, or may become encapsulated by fibrous tissue—“encysted tubercle.” Manual of Surgery Volume First: General Surgery. Sixth Edition. Its surface was jewel smooth, hyaline—yet beneath it was a suggestion of granulation, of close-packed, innumerable, microscopic crystals. The Metal Monster The poultices were directed to be discontinued, and the parts dressed every other day with sol. sulph. cupri, as the granulations were getting rather luxuriant. Diseases of the Horse's Foot Unhealthy granulations may be kept down by applying caustic occasionally. Common Diseases of Farm Animals It began now to discharge pus; granulations sprang up, and it healed. The Harvard Classics Volume 38 Scientific Papers (Physiology, Medicine, Surgery, Geology) Ultimately the dead bone becomes loose and lies in a cavity a little larger than itself; the wall of the cavity is formed by the new case, lined with granulation tissue. Manual of Surgery Volume First: General Surgery. Sixth Edition. Locally, the imperfect granulations should be scraped away, and some stimulating agent applied to the raw surface to promote the growth of healthy granulations. Manual of Surgery Volume First: General Surgery. Sixth Edition. These latter may be readily detected by their standing out as dark and uncovered spots in the healthy granulation around, and should be at once removed. Diseases of the Horse's Foot In such a wound, excessive and rapid granulation occurs, the new tissue piling up over the cut surfaces and appearing red and uneven. Common Diseases of Farm Animals Further, it shows that the mere contact of a foreign body does not of itself stimulate granulations to suppurate; whereas the presence of decomposing organic matter does. The Harvard Classics Volume 38 Scientific Papers (Physiology, Medicine, Surgery, Geology) The dead bone having been removed, the lining granulations are scraped away with a spoon, and the cavity is disinfected. Manual of Surgery Volume First: General Surgery. Sixth Edition. The term “proud flesh” is popularly applied to such redundant granulations. Manual of Surgery Volume First: General Surgery. Sixth Edition. They are small in size and have prominent granulations, and by the aid of a probe points of excessive tenderness may be discovered. Manual of Surgery Volume First: General Surgery. Sixth Edition. After the wound shows healthy granulations longer intervals should lapse between treatments. Common Diseases of Farm Animals The pyogenic membrane, like the granulations of a sore, which it resembles in nature, forms pus, not from any inherent disposition to do so, but only because it is subjected to some preternatural stimulation. The Harvard Classics Volume 38 Scientific Papers (Physiology, Medicine, Surgery, Geology) The presence of a foreign body is often suggested by a mass of redundant granulations at the mouth of the sinus. Manual of Surgery Volume First: General Surgery. Sixth Edition. The raw surface left after the separation of the dead skin may be allowed to heal by granulation, or may be covered by skin-grafts. Manual of Surgery Volume First: General Surgery. Sixth Edition. A sinus is lined by granulation tissue, and when it is of long standing the opening may be dragged below the level of the surrounding skin by contraction of the scar tissue around it. Manual of Surgery Volume First: General Surgery. Sixth Edition. In poorly cared for, and badly infected wounds, the part may become badly swollen, the granulations pile up and the wound refuse to "heal over." Common Diseases of Farm Animals The borders of the cells soon become more marked, a proof that their walls undergo a thickening; their protoplasm also becomes denser, and the granulations more distinct. The Harvard Classics Volume 38 Scientific Papers (Physiology, Medicine, Surgery, Geology) The base is soft, pale, and covered with feeble granulations and grey shreddy sloughs. Manual of Surgery Volume First: General Surgery. Sixth Edition. In any case it is necessary to disinfect the track, and, it may be, to remove the unhealthy granulations lining it, by means of the sharp spoon, or to excise it bodily. Manual of Surgery Volume First: General Surgery. Sixth Edition. They grow until they reach the level of the surrounding skin, and so fill the gap with a fine velvety mass of granulation tissue. Manual of Surgery Volume First: General Surgery. Sixth Edition. It may be advisable in such cases to cut away the excessive granulations and stop the haemorrhage by cauterization with a red-hot iron, or by compression. Common Diseases of Farm Animals Under this scab the formation of granulation tissue, its transformation into cicatricial tissue, and the growth of epithelium on the surface, go on until in the course of time the crust separates, leaving a scar. Manual of Surgery Volume First: General Surgery. Sixth Edition. If, however, at the inauguration of the tuberculous disease the bacilli prevail, the infection tends to spread into the tissues surrounding those originally infected, and more and more tuberculous granulation tissue is formed. Manual of Surgery Volume First: General Surgery. Sixth Edition. An extensive new formation of capillary loops and fibroblasts takes place towards the free surface, and goes on until the gap is filled by a fine velvet-like mass of granulation tissue. Manual of Surgery Volume First: General Surgery. Sixth Edition. These grafts may be placed either on a fresh raw surface or on healthy granulations. Manual of Surgery Volume First: General Surgery. Sixth Edition. The surrounding inflammation subsides, the discharge of pus lessens, and healing takes place by the formation of granulation tissue—the so-called “healing by second intention.” Manual of Surgery Volume First: General Surgery. Sixth Edition. At the edges the epithelium has proliferated and is covering over the newly formed granulation tissue. Manual of Surgery Volume First: General Surgery. Sixth Edition. The changes subsequent to the formation of tuberculous granulation tissue are liable to many variations. Manual of Surgery Volume First: General Surgery. Sixth Edition. Healing by Union of two Granulating Surfaces.—In gaping wounds union is sometimes obtained by bringing the two surfaces into apposition after each has become covered with healthy granulations. Manual of Surgery Volume First: General Surgery. Sixth Edition. The exudate on the surfaces causes them to adhere, capillary loops pass from one to the other, and their final fusion takes place by the further development of granulation and cicatricial tissue. Manual of Surgery Volume First: General Surgery. Sixth Edition. The walls of the abscess fall in; granulation tissue grows into the space and gradually fills it; and later this is replaced by cicatricial tissue. Manual of Surgery Volume First: General Surgery. Sixth Edition. Skin grafts may be applied to a raw surface or to one that is covered with granulations. Manual of Surgery Volume First: General Surgery. Sixth Edition. A tuberculous abscess results from the disintegration and liquefaction of tuberculous granulation tissue which has undergone caseation. Manual of Surgery Volume First: General Surgery. Sixth Edition. This granulation tissue is gradually replaced by young cicatricial tissue, and the surface is covered by the ingrowth of epithelium from the edges. Manual of Surgery Volume First: General Surgery. Sixth Edition. On removing the packing on the fifth or sixth day, the surface is found to be covered with minute, red, papillary granulations, which are beginning to fill up the cavity. Manual of Surgery Volume First: General Surgery. Sixth Edition. If only a small opening is made in the nail it is apt to be blocked by granulations. Manual of Surgery Volume First: General Surgery. Sixth Edition. Giant cells are not uncommon, but the endothelioid cells, which are so marked a feature of tuberculous granulation tissue, are practically absent. Manual of Surgery Volume First: General Surgery. Sixth Edition. The action of the threads is to convert the cyst wall into granulation tissue, which undergoes the usual conversion into scar tissue. Manual of Surgery Volume First: General Surgery. Sixth Edition. It is sometimes found necessary to employ moist or oily substances, such as boracic poultices, eucalyptus ointment, or balsam of Peru, to facilitate the separation of sloughs, or to promote the growth of granulations. Manual of Surgery Volume First: General Surgery. Sixth Edition. The caseation of tuberculous granulation tissue and its liquefaction is a slow and insidious process, and is unattended with the classical signs of inflammation—hence the terms “cold” and “chronic” applied to the tuberculous abscess. Manual of Surgery Volume First: General Surgery. Sixth Edition. Around each colony of actinomyces is a zone of granulation tissue in which suppuration usually occurs, so that the fungus comes to lie in a bath of greenish-yellow pus. Manual of Surgery Volume First: General Surgery. Sixth Edition. It is, however, only when the proliferative changes have come to predominate that the reparative process is effectively established by the production of healthy granulation tissue. Manual of Surgery Volume First: General Surgery. Sixth Edition. After granulations have formed, skin-grafting is of value in hastening healing. Manual of Surgery Volume First: General Surgery. Sixth Edition. This method of healing is sometimes spoken of as “healing by granulation”—although, as we have seen, it is by granulation that all repair takes place. Manual of Surgery Volume First: General Surgery. Sixth Edition. The base of a callous ulcer lies at some distance below the level of the swollen, thickened, and white edges, and presents a glazed appearance, such granulations as are present being unhealthy and irregular. Manual of Surgery Volume First: General Surgery. Sixth Edition. Sloughs of granulation tissue or of connective tissue may form. Manual of Surgery Volume First: General Surgery. Sixth Edition. These nodules break down by suppuration, and numerous minute abscesses lined by granulation tissues are thus formed. Manual of Surgery Volume First: General Surgery. Sixth Edition. The base of the ulcer becomes red and angry-looking, the granulations disappear, and a copious discharge of thin yellow pus, mixed with blood, escapes. Manual of Surgery Volume First: General Surgery. Sixth Edition. In extensive ulcers resulting from recent burns, if the granulations are healthy and aseptic, skin-grafts may safely be placed on them directly. Manual of Surgery Volume First: General Surgery. Sixth Edition. |
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