| 单词 | Gram-negative |
| 例句 | Gram-negative bacteria are getting less research attention because they are harder to find drugs against. Too few antibiotics in pipeline to tackle global drug-resistance crisis, WHO warns 2017-09-19T04:00:00Z Hiley envisioned them as the “Gram twins,” representing two different types of bacteria: Gram-positive and Gram-negative. In a Musical About Penicillin’s Inventor, Superbugs Take Center Stage 2022-10-21T04:00:00Z Both groups have a cell wall composed of peptidoglycan: in Gram-positive bacteria, the wall is thick, whereas in Gram-negative bacteria, the wall is thin. Fundamentals of Biology 2015-01-01T00:00:00Z Bacteria are divided into two major groups: Gram-positive and Gram-negative, based on their reaction to a procedure called Gram staining. Concepts of Biology 2013-04-25T00:00:00Z Gram-negative organisms have a thin cell wall and an outer envelope containing lipopolysaccharides and lipoproteins. Biology for AP Courses 2022-06-09T00:00:00Z Some deficiencies, such as those for complement, cause only a higher susceptibility to some Gram-negative bacteria. Anatomy and Physiology 2013-06-19T00:00:00Z Swabs from the skin, nose and mouth, as well as saliva and stool samples, showed that 34 percent of all participants had antibiotic-resistant bacteria, such as resistant Gram-negative bacilli or vancomycin-resistant enterococci. Living with Lead Creates Antibiotic-Resistant ‘Superbugs’ 2022-05-16T04:00:00Z In Gram-negative bacteria, the cell wall is surrounded by an outer membrane that contains lipopolysaccharides and lipoproteins. Fundamentals of Biology 2015-01-01T00:00:00Z Bacteria can be divided into two major groups: Gram-positive and Gram-negative. Concepts of Biology 2013-04-25T00:00:00Z For instance, antibody cross reactivity may occur against the similar surface structures of various Gram-negative bacteria. Biology for AP Courses 2022-06-09T00:00:00Z One group of bacteria, called Gram-negative bacteria, is particularly difficult to treat, because the cells are shielded by a double-membrane envelope, which constitutes a formidable barrier to antibiotics2. New antibiotics target the outer membrane of bacteria 2019-12-08T05:00:00Z As many as 16 percent of white coats tested positive for MRSA, and up to 42 percent for the bacterial class Gram-negative rods. Why Your Doctor’s White Coat Can Be a Threat to Your Health 2019-04-29T04:00:00Z Porins are proteins in this cell membrane that allow substances to pass through the outer membrane of Gram-negative bacteria. Fundamentals of Biology 2015-01-01T00:00:00Z Gram-negative organisms have a thin cell wall and an outer membrane. Concepts of Biology 2013-04-25T00:00:00Z Gram-negative bacteria have an inner cytoplasmic membrane separated by a peptidoglycan layer from a second outer membrane. Biology for AP Courses 2022-06-09T00:00:00Z Gram-negative bacteria are protected by inner and outer membranes. New antibiotics target the outer membrane of bacteria 2019-12-08T05:00:00Z This finding provides insight into how protein transit through both complexes is coordinated. b, Bacterial proteins that are part of protein complexes called BAM or TAM aid protein export in the Gram-negative group of bacteria. Exit route evolved into entry path in plants 2018-11-20T05:00:00Z In Gram-negative bacteria, a thin peptidoglycan cell wall is sandwiched between an outer and an inner plasma membrane. Fundamentals of Biology 2015-01-01T00:00:00Z Gram-negative bacteria have a cell wall made of peptidoglycan, while Gram-positive bacteria have a cell wall made of phospholipids. Concepts of Biology 2013-04-25T00:00:00Z The electron-transfer apparatus is simpler in Gram-positive bacteria than in Gram-negative bacteria. The electrifying energy of gut microbes 2018-09-11T04:00:00Z The three current studies took different approaches to develop antibiotics against Gram-negative bacteria. New antibiotics target the outer membrane of bacteria 2019-12-08T05:00:00Z In Gram-negative bacteria, when membrane proteins are transported from the cytoplasm to the outer membrane, they cross the inner membrane through a protein complex called Sec. Exit route evolved into entry path in plants 2018-11-20T05:00:00Z The cell wall of Gram-negative bacteria is thick, and the cell wall of Gram-positive bacteria is thin. Fundamentals of Biology 2015-01-01T00:00:00Z LPS is an essential component of the cell surface of a subset of bacterial pathogens called Gram-negative bacteria. An immune response with a sweet tooth 2018-08-14T04:00:00Z "Gram-negative bacteria cause pneumonia, blood and urinary tract infections as skin infections. We need new antibiotics to treat this class." New antibiotic family discovered in dirt 2018-02-12T05:00:00Z Together, these studies describe new antibiotics that are active against difficult-to-treat Gram-negative bacteria. New antibiotics target the outer membrane of bacteria 2019-12-08T05:00:00Z He and his colleagues finally identified the culprit: Gram-negative bacteria, named for the way they stain, that carry a molecule in their cell walls, a lipopolysaccharide. A Rare Brain Defect Is Linked to Gut Bacteria, Scientists Say 2017-05-10T04:00:00Z Porins allow entry of substances into both Gram-positive and Gram-negative bacteria. Fundamentals of Biology 2015-01-01T00:00:00Z All the potential medicines under development in this first phase target Gram-negative bacteria, among the most dangerous types of superbugs because they are increasingly resistant to most available antibiotics. Quest for new antibiotics gets first major funding from global partnership 2017-03-30T04:00:00Z False color scanning electron micrograph of Vibrio vulnificus, a species of Gram-negative, motile, curved, rod-shaped, pathogenic bacteria of the genus Vibrio that lives in marine environments such as estuaries, brackish ponds, or coastal areas. Living in a horror film: How Trump could make a deadly flesh-eating bacteria spread, again 2017-01-28T05:00:00Z Among the compounds the biotech discovered, starting last year, were the few dozen compounds that belong to a class of Gram-negative antibiotics known as aminoglycosides, according to Warp Drive Bio CEO Laurence Reid. Sanofi Partnership Passes First Test With Delivery of Antibiotic Compounds 2016-11-29T05:00:00Z In the old lab, mice without the gene carried enough Gram-negative bacteria to set off the disease. A Rare Brain Defect Is Linked to Gut Bacteria, Scientists Say 2017-05-10T04:00:00Z Structural studies elucidate the mechanism of a reaction that contributes to antibiotic resistance in Gram-negative bacteria. Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation | Science 2016-02-04T05:00:00Z A complex in the outer membrane of Gram-negative bacteria inserts other outer membrane proteins sideways. The structure of the β-barrel assembly machinery complex | Science 2016-01-07T05:00:00Z Gram-negative bacteria are among the most worrisome in medicine today because of the limited antibiotics against them. Merck, New England Patriots Boss Bet $30M on Antibiotics Startup, Spero 2015-06-08T04:00:00Z But it is ineffective against “Gram-negative” bacteria such as E. coli. The Superbug Armageddon Has Been Cancelled -- For Now 2015-01-08T05:00:00Z Only those that developed abscesses, which let large numbers of Gram-negative bacteria leak into their blood, developed the brain defect. A Rare Brain Defect Is Linked to Gut Bacteria, Scientists Say 2017-05-10T04:00:00Z Structural studies elucidate the mechanism of a reaction that contributes to antibiotic resistance in Gram-negative bacteria. Structures of aminoarabinose transferase ArnT suggest a molecular basis for lipid A glycosylation | Science 2016-02-04T05:00:00Z A complex in the outer membrane of Gram-negative bacteria inserts other outer membrane proteins sideways. The structure of the β-barrel assembly machinery complex | Science 2016-01-07T05:00:00Z The compound isn’t effective against so-called Gram-negative bacteria, increasingly feared in hospitals for their resistance to existing drugs. Microbe found in grassy field contains powerful antibiotic 2015-01-07T05:00:00Z But the fact that the antibiotic isn’t effective against most Gram-negative bacteria is slightly disappointing. A new antibiotic discovery promises more help in the fight against resistance 2015-01-07T05:00:00Z Zerbaxa treats Gram-negative bacteria, a group named for its appearance in Gram identification stains. FDA OKs Cubist antibiotic for serious infections 2014-12-19T05:00:00Z Silver acts against Gram-negative bacteria - one of the two main types of bacteria - which are particularly difficult pathogens to treat. Silver 'boost to antibiotic success' 2013-06-20T06:21:51Z Additionally, we demonstrate in vitro and in two different mouse models of peritonitis that silver sensitizes Gram-negative bacteria to the Gram-positive–specific antibiotic vancomycin, thereby expanding the antibacterial spectrum of this drug. [Research Articles] Silver Enhances Antibiotic Activity Against Gram-Negative Bacteria 2013-06-19T18:55:08.280Z In vivo, peptide treatment increased phagocyte recruitment and accelerated bacterial clearance in murine models of Gram-negative and Gram-positive bacterial peritonitis. [Research Articles] Targeting the TLR Co-Receptor CD14 with TLR2-Derived Peptides Modulates Immune Responses to Pathogens 2013-05-15T18:55:06.783Z Gram-negative bacteria on the tongue may produce most of the foul odors in breath, but recent research emphasizes that no single type of oral bacterium creates bad breath on its own. To Beat Bad Breath, Keep the Bacteria in Your Mouth Happy 2013-05-05T14:15:02.467Z Gram-negative bacteria include E. coli, Salmonella, Shigella and other species in the class known as Enterobacteriaceae bacteria. Drug pipeline for worst superbugs "on life support": report 2013-04-18T04:09:43Z In contrast, the Gram-negative bacteria are not really a natural grouping, but more of an “everything else”. The Dark Bacillus Crystal 2012-12-20T21:45:00.373Z At least one of the microbial products that induces this process is peptidoglycan derived from Gram-negative bacteria. Reciprocal interactions of the intestinal microbiota and immune system 2012-09-13T11:20:55.227Z The Gram-negative bacteria Klebsiella pneumoniae is a major cause of nosocomial infections, primarily among immunocompromised patients. [Research Articles] Tracking a Hospital Outbreak of Carbapenem-Resistant Klebsiella pneumoniae with Whole-Genome Sequencing 2012-08-22T18:55:22.163Z The paper also highlights the dangers of resistant Gram-negative bacteria like Klebsiella p., he adds. 'Genomic CSI' Helps Contain a Killer 2012-08-22T19:09:39Z KPC is part of the so-called Gram-negative group of bacteria, which also includes E. coli and Pseudomonas. Greek Doctors Battle Hospital Superbug as Crisis Depletes Budget 2012-02-09T23:17:08Z These compounds appear to be effective against both Gram-negative and Gram-positive bacteria. Lunchtime science 2011-10-12T17:20:55.227Z Expression of — and signalling by — TLR4, which is the receptor for the abundant product of Gram-negative bacteria, lipopolysaccharide, are significantly increased antecedent to intestinal colonization at birth. Reciprocal interactions of the intestinal microbiota and immune system 2012-09-13T11:20:55.227Z “We are all seeing so many difficult or impossible to treat Gram-negative bacteria infections, and there’s nothing in the pipeline capable of fighting the most resistant of them.” Prostate Exam Deaths From ‘Superbugs’ Spur Cancer-Test Inquiry 2011-05-05T22:00:28Z As Maryn McKenna explains in "," antibiotic resistance in the gram-negative bacteria is particularly worrisome because Gram-negative germs are more likely than Gram-positive ones to share the genes responsible for drug resistance across species. Antibiotic Resistance Is Taking Out "Last-Resort" Drugs Used to Combat Worrisome Category of Germs 2011-04-01T22:15:00.463Z Gram-negative bugs are more sophisticated organisms, easily able to acquire and pass resistance between each other, AstraZeneca’s Rex said. Greek Doctors Battle Hospital Superbug as Crisis Depletes Budget 2012-02-09T23:17:08Z Carbapenems are key antibiotic weapons against these "Gram-negative" bacteria, which already are challenging to treat. Drug-resistant superbugs reach 3 states 2010-09-14T15:57:00Z Because Reg-III is selectively bactericidal for Gram-positive bacteria, it is likely that antimicrobial peptides specific for Gram-negative bacteria also contribute to the microbe-sparse zone. Reciprocal interactions of the intestinal microbiota and immune system 2012-09-13T11:20:55.227Z By comparison, the drug-resistant Gram-negative germs for the most part threaten only hospitalized patients whose immune systems are weak. A Rising Threat of Infections Unfazed by Antibiotics 2010-02-27T00:36:00Z The latter are Gram-negative, and vary greatly in both dimensions as well as in form. The Bacillus of Long Life a manual of the preparation and souring of milk for dietary purposes, together with and historical account of the use of fermente But for a combination of business reasons and scientific challenges, the pharmaceuticals industry is pursuing very few drugs for Acinetobacter and other organisms of its type, known as Gram-negative bacteria. A Rising Threat of Infections Unfazed by Antibiotics 2010-02-27T00:36:00Z All strains show tendency to chain formation, some being arranged 116in chains of six to twenty-five segments, which may contain both Gram-positive and Gram-negative individuals. The Bacillus of Long Life a manual of the preparation and souring of milk for dietary purposes, together with and historical account of the use of fermente |
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