单词 | globin |
例句 | The globin chains are too short to form functional hemoglobin. Biology for AP Courses 2022-06-09T00:00:00Z Carbon dioxide does not bind to iron as oxygen does; instead, carbon dioxide binds amino acid moieties on the globin portions of hemoglobin to form carbaminohemoglobin, which forms when hemoglobin and carbon dioxide bind. Anatomy and Physiology 2013-06-19T00:00:00Z Even Linus Pauling, who famously discovered that sickle cell was caused by the substitution of a single amino acid in the globin protein, was part of this dismal history. Sickle Cell Math Is Brutally Simple, but Not Widely Taught 2021-12-28T05:00:00Z But that gene, the adult globin gene, is the one that can carry a sickle cell mutation. Pioneering gene therapy freed her of sickle cell. Is a cure at hand? 2021-09-14T04:00:00Z The earliest protein — a common ancestor of haemoglobin and the monomeric globin protein myoglobin, named AncMH by the authors — exists only as a monomer. Extinct proteins resurrected to reconstruct the evolution of vertebrate haemoglobin 2020-05-19T04:00:00Z Fewer globin chains are synthesized because less mRNA is transcribed. Biology for AP Courses 2022-06-09T00:00:00Z The hemoglobin molecule contains four globin proteins bound to a pigment molecule called heme, which contains an ion of iron. Anatomy and Physiology 2013-06-19T00:00:00Z Hemoglobin arose out of four interlinked globin proteins, each holding a heme, and it rapidly became ubiquitous. Icefish Study Adds Another Color to the Story of Blood 2019-05-06T04:00:00Z Bluebird Bio has a different strategy — using a disabled virus to deliver a copy of a functioning globin gene. Pioneering gene therapy freed her of sickle cell. Is a cure at hand? 2021-09-14T04:00:00Z The normal gene codes for a protein called globin, which helps red blood cells carry oxygen to the body’s tissues. How 3-D Printing Is Changing Medicine 2014-11-17T05:00:00Z The globin chains produced are too long to form functional hemoglobin. Biology for AP Courses 2022-06-09T00:00:00Z A patient has thalassemia, a genetic disorder characterized by abnormal synthesis of globin proteins and excessive destruction of erythrocytes. Anatomy and Physiology 2013-06-19T00:00:00Z Vertebrates typically carry genes for several variant globin proteins with finely tuned uses. Icefish Study Adds Another Color to the Story of Blood 2019-05-06T04:00:00Z Bluebird’s treatment uses a modified HIV virus, known as a lentivirus, to replace the defective gene for beta globin in the blood-producing stem cells found in these bones. New Gene Therapy Rapidly Helps Patients With Rare Blood Disorder 2014-06-14T04:00:00Z Another example from the same fold is the evolution of the globin family of genes, with hemoglobin carrying oxygen in the bloodstream and myglobin binding it in the muscles. Gene duplication frees up enzymes for molecular promiscuity 2012-07-28T11:45:06.120Z Conservation of codons means that a purified mRNA encoding the globin protein in horses could be transferred to a tulip cell, and the tulip would synthesize horse globin. Biology for AP Courses 2022-06-09T00:00:00Z The gamma globin gene is active only in the fetus. Mammoth Hemoglobin Offers More Clues to Its Arctic Evolution 2010-05-03T23:05:00Z Our skeletal muscles make myoglobin, a single globin protein ancestral to hemoglobin, which helps muscle hang on to a reserve of oxygen to use during exercise. Icefish Study Adds Another Color to the Story of Blood 2019-05-06T04:00:00Z And as a coup de grâce, the isolated globin proteins can clog the filtration system of the kidneys and shut them down. Icefish Study Adds Another Color to the Story of Blood 2019-05-06T04:00:00Z The team’s next step was to synthesize copies of the mammoth’s two globin genes. Mammoth Hemoglobin Offers More Clues to Its Arctic Evolution 2010-05-03T23:05:00Z The mammoth genes were then inserted into bacteria, which synthesized the two mammoth globin chains, inserted the required iron atoms, and assembled the chains into working hemoglobin molecules. Mammoth Hemoglobin Offers More Clues to Its Arctic Evolution 2010-05-03T23:05:00Z Dr. Campbell figured that the hemoglobin system of living elephants would offer the best guide to how mammoth globin genes operate. Mammoth Hemoglobin Offers More Clues to Its Arctic Evolution 2010-05-03T23:05:00Z Compounding the problem is that hemoglobin, when unprotected in blood plasma, decomposes into its component globin subunits. Icefish Study Adds Another Color to the Story of Blood 2019-05-06T04:00:00Z |
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