| 单词 | angiogenesis |
| 例句 | Tumors, hungry for oxygen and nutrients, would have to stimulate new blood vessels to sprout and grow to them; by preventing these vessels from forming, angiogenesis inhibitors should starve tumors and curb their growth. Failed cancer therapy revived as powerful tumor killer when combined with newer drugs 2023-05-16T04:00:00Z “It works by angiogenesis or creating new blood vessel formation,” says John L. Ferrell III, director of sports medicine for D.C.- based Regenerative Orthopedics and Sports Medicine. The ‘most common crippling hand condition’ you’ve never heard of 2022-11-20T05:00:00Z The training can trigger the formation of more extensive capillary networks around the fiber, a process called angiogenesis, to supply oxygen and remove metabolic waste. Anatomy and Physiology 2013-06-19T00:00:00Z A similar approach has been used to stimulate the growth of blood vessels in the heart and neck, so the therapy, known as therapeutic angiogenesis, is well established postnatally. Prenatal gene therapy offers the earliest possible cure 2018-12-11T05:00:00Z When it is functioning, VHL suppresses tumours by regulating angiogenesis — the formation of new blood vessels. Targeted therapy: An elusive cancer target : Nature : Nature Research 2016-09-13T04:00:00Z By restoring normal circulation in the tumor, angiogenesis inhibitors may reverse the immune-suppressing conditions and permit tumor-targeting T cells to pounce. Failed cancer therapy revived as powerful tumor killer when combined with newer drugs 2023-05-16T04:00:00Z This includes the expression of genes that are involved in host nutrient absorption and processing, barrier functions, gut motility, intestinal immune responses, angiogenesis and the metabolism of xenobiotics. The microbiome and innate immunity : Nature : Nature Publishing Group 2016-07-05T04:00:00Z This angiogenesis—the creation of new blood vessels from existing ones—continues as needed throughout life as we grow and develop. Anatomy and Physiology 2013-06-19T00:00:00Z Folkman himself famously struggled to convince the many angiogenesis skeptics among cancer researchers. Tumors have found a bloody new way to grow and spread 2016-06-16T04:00:00Z Another new class of drug targets a different enzyme linked to angiogenesis, known as mTOR. Targeted therapy: An elusive cancer target : Nature : Nature Research 2016-09-13T04:00:00Z And some extend patients’ lives by many months over angiogenesis inhibitors alone. Failed cancer therapy revived as powerful tumor killer when combined with newer drugs 2023-05-16T04:00:00Z “It also kickstarts angiogenesis, which is the creation of new blood vessels, and helps repair damaged ones.” Hyperbaric chambers offer natural wound care benefits 2016-06-03T04:00:00Z Explain why drugs called angiogenesis inhibitors would be used in cancer treatment. Anatomy and Physiology 2013-06-19T00:00:00Z But by the late 1990s, drug companies were bustling to develop compounds that curtail angiogenesis, and DNA pioneer James Watson announced that Folkman’s approach would “cure cancer in 2 years.” Tumors have found a bloody new way to grow and spread 2016-06-16T04:00:00Z Tumours need their own blood supply to grow, the loss of VHL allows this angiogenesis. Targeted therapy: An elusive cancer target : Nature : Nature Research 2016-09-13T04:00:00Z “We are making the same mistakes we made the first time” with angiogenesis inhibitors, he says, adding, “We should take our time and think a little bit.” Failed cancer therapy revived as powerful tumor killer when combined with newer drugs 2023-05-16T04:00:00Z Scientists are seeking ways to block tumor angiogenesis. U2 guitarist The Edge makes history as he rocks Sistine Chapel for cancer 2016-05-01T04:00:00Z Vasotide prevents the excessive growth of blood vessels, termed angiogenesis, by stopping a protein called vascular endothelial growth factor from binding to two receptors on blood-vessel walls, the study said. How the Brain Regulates Simultaneous Pains 2015-10-26T04:00:00Z “Vasculogenic mimicry is one of the ways in which tumors develop a blood supply independently from classical angiogenesis.” Tumors have found a bloody new way to grow and spread 2016-06-16T04:00:00Z I really wanted to solve this because I wanted to isolate this angiogenesis inhibitor. Nanotech Pioneer Langer Wins Award by Thinking Small 2015-02-10T05:00:00Z More than 200 clinical trials are now testing this approach in various kinds of cancers, spurred by evidence that angiogenesis inhibitors help cancer-fighting T cells find their way deep into tumors. Failed cancer therapy revived as powerful tumor killer when combined with newer drugs 2023-05-16T04:00:00Z The rock star sprinkled his address with technical terms such as bio markers and angiogenesis. U2 guitarist The Edge makes history as he rocks Sistine Chapel for cancer 2016-05-01T04:00:00Z Among other things, she was soon writing 15-page primers on tumour angiogenesis and treatments for multiple sclerosis. Public relations: For your information 2014-04-30T17:20:43.825Z This process, called angiogenesis, is also exploited by a tumor as it fuels its growth by creating its own parasitic blood supply. Raw Data: A Tumor, the Embryo’s Evil Twin 2014-03-17T20:26:20Z I felt like if I couldn’t do that, I couldn’t develop this bioassay to study angiogenesis. Nanotech Pioneer Langer Wins Award by Thinking Small 2015-02-10T05:00:00Z This resurgence for angiogenesis inhibitors comes after astronomical expectations for the drugs were dashed in the late 1990s. Failed cancer therapy revived as powerful tumor killer when combined with newer drugs 2023-05-16T04:00:00Z Later, recovery of endothelial Angiopoetin-2 expression facilitates angiogenesis in the regenerating liver in a vascular endothelial growth factor receptor 2–dependent manner. [Report] Endothelial Cell-Derived Angiopoietin-2 Controls Liver Regeneration as a Spatiotemporal Rheostat 2014-01-23T19:26:26.766Z It must learn to initiate angiogenesis—the sprouting of its own blood vessels—and finally to eat into surrounding tissue and to metastasize. Book Excerpt: George Johnson Explores the Latest Discoveries about Cancer (preview) 2013-11-04T13:15:00.340Z The formation of new blood vessels, known as angiogenesis, satisfies these needs. The Hallmarks of Cancer 5: Sustained Angiogenesis 2013-10-19T00:45:00.460Z Both drugs work by stopping a process called angiogenesis, which in feeds tumors and, in eye disease, results in too much blood entering the eye and causing damage. Billionaires Anoint Biogeeks 2013-02-20T16:04:30Z The monoclonal antibody bevacizumab gained regulatory approval in 2004 for patients with advanced colon cancer, and more than a dozen other angiogenesis inhibitors have since joined the antitumor arsenal. Failed cancer therapy revived as powerful tumor killer when combined with newer drugs 2023-05-16T04:00:00Z Endostatin is one of the so-called angiogenesis inhibitors, a group of much-touted drugs that block the formation of new blood vessels that tumors need for growth. Tumor Blocker May Fight Fibrosis 2012-05-30T19:00:00Z Forty years ago, Judah Folkman predicted that tumor growth is dependent on angiogenesis and that inhibiting this process might be a new strategy for cancer therapy. [Reviews] Forty-Year Journey of Angiogenesis Translational Research 2011-12-21T20:25:06.737Z Angiogenesis Inhibition How important is angiogenesis for cancer progression? The Hallmarks of Cancer 5: Sustained Angiogenesis 2013-10-19T00:45:00.460Z This strategy, known as angiogenesis inhibition, is the basis for more than 15 drugs used to treat cancers of the brain, colon, lungs and kidneys. Cancer drug helps obese monkeys lose weight ? fast 2011-11-10T05:14:24Z But on their own, angiogenesis inhibitors typically add only a few months to patients’ lives. Failed cancer therapy revived as powerful tumor killer when combined with newer drugs 2023-05-16T04:00:00Z Immune system cells, maneuvered into behaving as if they were healing a wound, emit growth factors that embolden the tumor and stimulate angiogenesis, the generation of new blood vessels. Cancer?s Secrets Come Into Sharper Focus 2011-08-15T17:02:05Z Here, we guide readers through 40 years of angiogenesis research and discuss challenges of antiangiogenic therapy. [Reviews] Forty-Year Journey of Angiogenesis Translational Research 2011-12-21T20:25:06.737Z The angiogenesis within the context of a tumor is a warped, twisted version of what it should be; the vessels are convoluted and excessively branched. The Hallmarks of Cancer 5: Sustained Angiogenesis 2013-10-19T00:45:00.460Z To date, however, the promise of angiogenesis hasn’t been achieved. Could Bypass Surgeries Become a Thing of the Past? 2011-04-18T13:34:45Z In people with diabetes defective angiogenesis is implicated in peripheral vascular disease, which often leads to limb amputations. Mouse Study Reveals Mechanism behind Diabetes Blood Vessel Damage 2011-02-18T15:15:04.180Z Most of these genes encode transcription factors associated with angiogenesis and wound repair — including EPAS1, a gene that is transcribed three times as much in the gut cells of breastfed infants. Development: Mother's milk: A rich opportunity 2011-01-04T22:22:32.713Z Avastin is the first medicine to fight cancer by blocking the growth of blood vessels that feed tumors, a process called angiogenesis. Cancer drug Avastin doesn't fare well in study 2010-12-11T04:08:00Z Counterbalancing positive and negative signals circulate in the cellular microenvironment surrounding every cell, respectively encouraging or blocking angiogenesis. The Hallmarks of Cancer 5: Sustained Angiogenesis 2013-10-19T00:45:00.460Z MRI highlights angiogenesis, the formation of new blood vessels, especially those that feed cancerous tissues. Women With Breast Cancer History Should Consider MRI: Study 2010-11-29T14:00:00Z This binding also might play a role in angiogenesis, the formation of new blood vessels. Protein Implicated in Many Cancers 2010-10-21T15:43:00Z However, some intriguing newer research suggests plants may protect us from cancer in a far more novel way they may block a cancer's ability to grow via a process known as angiogenesis. Enlist fruits and vegetables in cancer fight 2010-10-15T20:55:00Z I was at a lecture there a year ago on angiogenesis — new blood vessels. "Roadmap to 100," author says its all about exercise and diet 2010-05-03T19:46:00Z In the course of normal development, the arrangement of our blood vessels is fixed; angiogenesis is switched off. The Hallmarks of Cancer 5: Sustained Angiogenesis 2013-10-19T00:45:00.460Z Simply put, they change the balance of angiogenesis inducers and counteracting inhibitors in the surrounding cellular environment. The Hallmarks of Cancer 5: Sustained Angiogenesis 2013-10-19T00:45:00.460Z To multiply, cancer cells begin producing chemicals that initiate angiogenesis — in other words, they learn to feed themselves by creating their own blood supply. Enlist fruits and vegetables in cancer fight 2010-10-15T20:55:00Z In a healthy person, angiogenesis is finely regulated; it starts when new blood vessels are needed and stops when that new growth is complete. Enlist fruits and vegetables in cancer fight 2010-10-15T20:55:00Z The plant chemicals in these foods seem to be able to inhibit angiogenesis so that a single cancer cell or cluster of cancer cells is never able to grow enough to cause any mischief. Enlist fruits and vegetables in cancer fight 2010-10-15T20:55:00Z In this image, angiogenesis causes blood vessels to sprout more branches. The Hallmarks of Cancer 5: Sustained Angiogenesis 2013-10-19T00:45:00.460Z |
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