单词 | aneuploidy |
例句 | Human embryos experience unusually high rates of chromosome gain and loss, known as aneuploidy, in early development. Researchers studied thousands of fertility attempts hoping to improve IVF 2023-10-02T04:00:00Z When random mistakes occur during chromosome replication, fertilized eggs can inherit cells with these errors and result in a condition called aneuploidy, which essentially means "the wrong number of chromosomes." Most human embryos naturally die after conception 2022-09-05T04:00:00Z The PGT-A test is used to screen for aneuploidy, which is when an improper number of chromosomes — either too few or too many — is detected in sampled cells. Study raises questions about popular genetic test for ‘abnormal’ embryos 2022-04-20T04:00:00Z The factors that govern whether or not a tumour will tolerate aneuploidy remain mostly unknown. Watching cancer cells evolve through chromosomal instability 2019-06-02T04:00:00Z The test also checked the samples for aneuploidy, the presence of abnormal numbers of chromosomes in cells. Modified Pap smears provide early detection for two deadly gynecologic cancers 2018-03-23T04:00:00Z Scientists have studied aneuploidy for decades by screening IVF embryos, and these mishaps are well understood to be the cause of pregnancy loss in humans. Researchers studied thousands of fertility attempts hoping to improve IVF 2023-10-02T04:00:00Z With the instructions for development now disorganized due to mixed-up chromosomes, embryos with aneuploidy are usually doomed. Most human embryos naturally die after conception 2022-09-05T04:00:00Z Thompson, S. L. & Compton, D. A. Examining the link between chromosomal instability and aneuploidy in human cells. Chromosomal instability drives metastasis through a cytosolic DNA response 2018-01-16T05:00:00Z Finally, aneuploidy is emerging as a possible early event driving tumour evolution12,13, but information about the frequency and types of chromosomal instability during the initial stages of tumour evolution is extremely limited. Watching cancer cells evolve through chromosomal instability 2019-06-02T04:00:00Z A search through genome sequences from more than 5,000 human tumours representing 12 cancer types showed that those with a high degree of aneuploidy tended to contain fewer immune cells. Cancer: Chromosome total affects therapy : Nature : Nature Research 2017-01-24T05:00:00Z Because aneuploidy is rare in many other species, McCoy said, the findings could help explain why pregnancy loss and miscarriage are so common in humans. Researchers studied thousands of fertility attempts hoping to improve IVF 2023-10-02T04:00:00Z They didn’t understand the science behind Down syndrome, terms like “trisomy” and “aneuploidy.” Most people saw limits for this boy with Down syndrome. His parents saw potential. 2016-03-02T05:00:00Z Merotelic kinetochore orientation is a major mechanism of aneuploidy in mitotic mammalian tissue cells. Chromosomal instability drives metastasis through a cytosolic DNA response 2018-01-16T05:00:00Z The variant in a woman's genome, which causes errors in the cell replication process, is strongly associated with risk of aneuploidy -- an abnormal number of chromosomes in a cell, the researchers said. Common Gene Variant May Raise Miscarriage Risk, Study Finds 2015-10-08T04:00:00Z Cancer biologist Jan van Deursen at the Mayo Clinic in Rochester, Minnesota, and his colleagues were initially interested in studying a common feature of cancers, called aneuploidy. Revved-Up Protein Fights Aging 2012-12-16T18:00:00Z Figure 3: Analysis of aneuploidy and chromosome instability in retinoblastoma. A novel retinoblastoma therapy from genomic and epigenetic analyses 2012-01-18T18:21:09.930Z “It looks like aneuploidy is in other tissues, and that’s not very well appreciated right now,” Duncan says. Vital Flaw 2010-09-23T15:16:00Z Sheltzer, J. M. A transcriptional and metabolic signature of primary aneuploidy is present in chromosomally unstable cancer cells and informs clinical prognosis. Chromosomal instability drives metastasis through a cytosolic DNA response 2018-01-16T05:00:00Z The investigators found the gene variant known as rs2305957 was strongly associated with risk of aneuploidy. Common Gene Variant May Raise Miscarriage Risk, Study Finds 2015-10-08T04:00:00Z They used mice to show that aneuploidy is probably a result of poor chromosome cohesion. Why It's Harder For Older Women to Have Healthy Babies 2010-09-22T14:20:00Z Figure 3: Analysis of aneuploidy and chromosome instability in retinoblastoma. a, Chromosomal mis-segregation of SJRB001X cells after at least 21 rounds of cell division is plotted in red. A novel retinoblastoma therapy from genomic and epigenetic analyses 2012-01-18T18:21:09.930Z A woman's age affects the risk for aneuploidy, but the study authors theorized that genetics also played a role. Common Gene Variant May Raise Miscarriage Risk, Study Finds 2015-10-08T04:00:00Z But aneuploidy upends the normal path of cell division. Why It's Harder For Older Women to Have Healthy Babies 2010-09-22T14:20:00Z |
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