| 单词 | androgen |
| 例句 | Until I reached puberty and androgens flooded my bloodstream, the ways in which I differed from other litde girls were hard to detect. Middlesex: A Novel 2002-06-05T00:00:00Z You could even start before you were eighteen with pills called androgen blockers that stopped the boy hormones already inside you from turning your body into a man's. George 2015-08-25T00:00:00Z She successfully challenged her 1985 disqualification on the grounds that she also has androgen insensitivity syndrome, a condition in which her body cannot respond to testosterone, either natural or synthetic. Forget blade runners: What if some female Olympians have high testosterone? 2016-08-16T04:00:00Z Dr. Engelman likes Prose, which makes supplements that are tailored to age, hair type, lifestyle and other factors, and the prescription drug spironolactone, which is an androgen blocker and can also help with acne. Feeling Bad About … Your Hair? 2021-12-21T05:00:00Z But they appear to resolve decades of contradictory findings about the heart safety of testosterone treatment for men who have a medical condition called androgen deficiency, or hypogonadism. Testosterone Therapy Does Not Raise Heart Risk in a Group of Men 2023-06-16T04:00:00Z The activity of the sebaceous glands increases during puberty because of heightened levels of androgens. Fundamentals of Biology 2015-01-01T00:00:00Z “Special emphasis was placed on administering androgens to women and adolescent girls because this practice proved to be particularly effective for sports performance.” Werner Franke, Who Exposed East German Doping Program, Dies at 82 2022-12-04T05:00:00Z Examples of steroid hormones include estradiol, which is an estrogen, or female sex hormone, and testosterone, which is an androgen, or male sex hormone. Biology for AP Courses 2022-06-09T00:00:00Z So some dermatologists, including Dr. Sinclair, have added another drug — very low doses of spironolactone, a blood pressure drug that also blocks certain sex hormones called androgens — to try to prevent unwanted hair growth. An Old Medicine Grows New Hair for Pennies a Day, Doctors Say 2022-08-18T04:00:00Z The work of Tobiansky and his colleagues suggests that steroid hormones such as androgens and estrogens may have protective effects on the birds’ brain. Head-Banging Woodpeckers Could Give Themselves a Concussion Every Day: Here’s How They Avoid It 2022-07-14T04:00:00Z In particular, BPA mimics the hormonal effects of estrogens and has the opposite effect—that of androgens. Anatomy and Physiology 2013-06-19T00:00:00Z Many women who have androgen insensitivity syndrome never know that they have a Y chromosome. Opinion | Requiring fixed, binary sex on birth certificates erases real Oklahomans 2022-05-19T04:00:00Z Other steroid hormones include aldosterone and cortisol, which are released by the adrenal glands along with some other types of androgens. Biology for AP Courses 2022-06-09T00:00:00Z Early on, some scientists suspected the reason was primarily biological, and that sex-based treatments for men — like estrogen injections or androgen blockers — could help reduce their risk of dying. Why Are Men More Likely to Die of Covid? It’s Complicated. 2022-01-19T05:00:00Z As women get closer to menopause, he said, the balance of hormones in their bodies shifts, and they can start producing more male-type hormones known as androgens. Why Do Women Sprout Chin Hairs as They Age? 2021-12-14T05:00:00Z Hormones, such as androgens, stimulate the release of sebum. Anatomy and Physiology 2013-06-19T00:00:00Z Food and Drug Administration-approved androgen receptor blocker to see whether it produces comparable results. ‘Too good to be true’: Doubts swirl around trial that saw 77% reduction in COVID-19 mortality 2021-07-07T04:00:00Z The most widely known androgen in males is testosterone. Biology for AP Courses 2022-06-09T00:00:00Z Animals form bonds through a number of chemical messengers acting in the brain to regulate social connection, such as oxytocin, vasopressin, glucocorticoids, endogenous opioids, and hormones, including androgens and estrogens. How catfishers exploit basic human neuroscience 2021-05-31T04:00:00Z These cysts lead to increased androgen production, promoting hair growth, Dr. Cohen explained, resulting in coarser, darker hair. Why Do Women Sprout Chin Hairs as They Age? 2021-12-14T05:00:00Z During puberty and most of adulthood, androgens are produced in the gonads. Anatomy and Physiology 2013-06-19T00:00:00Z The preprint also claims the drug, which blocks the activity of androgens—male hormones such as testosterone—cut patients’ average hospital stay by 5 days, far more than any other treatment yet tested. ‘Too good to be true’: Doubts swirl around trial that saw 77% reduction in COVID-19 mortality 2021-07-07T04:00:00Z The hair loss condition is controlled by variations in the androgen receptor, or AR, gene, which affects how the body responds to androgens, or hormones such as testosterone. Balding men appear at higher risk for severe COVID-19, researchers find 2021-05-07T04:00:00Z The high-speed wing clapping in some species requires extra fast and powerful wing pectoral muscles—which are highly sensitive to the male hormone androgen. The genes behind the sexiest birds on the planet 2021-03-03T05:00:00Z The link to androgen excess is new and important — it’s the first pathogenic pathway associated with IIH to be found. Treating headache to save sight 2020-10-13T04:00:00Z The androgens produced in the zona reticularis supplement the gonadal androgens. Anatomy and Physiology 2013-06-19T00:00:00Z “Obese people have more androgens and male hormones. Maybe that’s impacting the virus affecting the cells,” she hypothesized. One man’s battle shows why covid-19 and obesity are a toxic mix 2020-09-04T04:00:00Z “The identification of a biomarker connected with the androgen receptor is another piece of evidence highlighting the important role of androgens in COVID-19 disease severity,” he said in a statement Thursday. Balding men appear at higher risk for severe COVID-19, researchers find 2021-05-07T04:00:00Z First, the female immune system is simply stronger at just about every level, partly because female estrogen hormones tend to amp up the immune system, whereas male androgen hormones tend to dial it back. Why Some People Get Terribly Sick from COVID-19 2020-08-20T04:00:00Z And preliminary observations from Spain suggest that a disproportionate number of men with male pattern baldness—which is linked to a powerful androgen—end up in hospitals with COVID-19. Why coronavirus hits men harder: sex hormones offer clues 2020-06-03T04:00:00Z This means that very low concentrations of androgens or estrogens will negatively feed back onto the hypothalamus and pituitary, keeping the production of GnRH, LH, and FSH low. Anatomy and Physiology 2013-06-19T00:00:00Z As a urologist workings in testosterone therapy and research, Mills questioned how the studies accounted for testosterone, considering how androgen receptors are on the lungs. Experts doubt coronavirus patients will see 'miracle cure' from hormone therapy 2020-04-28T04:00:00Z But about one-third of them receive androgen deprivation therapy. Perspective | I’m an oncologist who treats prostate cancer. For many patients and their manhood, the cure seems worse than the disease. 2020-04-10T04:00:00Z Where I had chemotherapy, I have something called androgen deprivation therapy where they take the testosterone out of your body, which basically gives you male menopause. John Tesh recalls how he was 'ready to take’ himself ‘out’ while battling cancer: 'I was angry at God' 2020-03-26T04:00:00Z Researchers are rushing to test already approved drugs that block androgens’ effects, deploying them early in infection in hopes of slowing the virus and buying time for the immune system to beat it back. Why coronavirus hits men harder: sex hormones offer clues 2020-06-03T04:00:00Z The placenta converts weak androgens secreted by the maternal and fetal adrenal glands to estrogens, which are necessary for pregnancy to progress. Anatomy and Physiology 2013-06-19T00:00:00Z Similarly, 21.6% of those who got androgen deprivation and 15.8% of those who didn’t were diagnosed with other forms of dementia. Risk of dementia rises with prostate cancer hormone-blocking therapy 2019-07-03T04:00:00Z “It’s called androgen deprivation therapy,” I said, “but you can call it hormone therapy.” Perspective | I’m an oncologist who treats prostate cancer. For many patients and their manhood, the cure seems worse than the disease. 2020-04-10T04:00:00Z Boosting DHT levels in pregnant mice induced higher, more feminine digit ratios in the hind paws of male pups, whereas blocking the androgen receptor led to lower, more masculine ratios in female pups. Talk to the hand. Scientists try to debunk idea that finger length can reveal personality and health 2019-06-06T04:00:00Z “Our conclusion supports the hypotheses that androgen signaling might increase the risk of severe outcomes from COVID-19 and that androgen deprivation may limit those severe outcomes,” Oh says. Why coronavirus hits men harder: sex hormones offer clues 2020-06-03T04:00:00Z They produce both sperm and androgens, such as testosterone, and are active throughout the reproductive lifespan of the male. Anatomy and Physiology 2013-06-19T00:00:00Z It also has a testosterone-like compound, or androgen, which balances a drop in the male hormone caused by the progestin. Hopes rise for male contraceptive pill breakthrough 2019-03-25T04:00:00Z It may be that slight benefits in survival from using androgen or other novel therapies are not going to be worth the long-term physical and emotional side effects of castrating a man. Perspective | I’m an oncologist who treats prostate cancer. For many patients and their manhood, the cure seems worse than the disease. 2020-04-10T04:00:00Z "I think there is no longer any doubt that these ratios in humans reflect prenatal androgen exposure," Breedlove says. Talk to the hand. Scientists try to debunk idea that finger length can reveal personality and health 2019-06-06T04:00:00Z It degrades the androgen receptor, a protein that is already targeted by a handful of approved drugs. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z The adrenal cortex—the outer layer of the gland—produces mineralocorticoids, glucocorticoids, and androgens. Anatomy and Physiology 2013-06-19T00:00:00Z The organization added that, following the medical policies adopted by the International Powerlifting Federation, it does not permit the use of “testosterone or other androgens, commonly used to assist in transition from female to male.” USA Powerlifting organization bans transgender women from competing 2019-02-05T05:00:00Z Though Sophia’s acne was more challenging than most cases, it finally responded to a combination of the androgen blocker spironolactone and oral contraceptives, and she’s now looking forward to a far less stressful senior year. Managing Teenage Acne 2019-01-07T05:00:00Z I don’t know a more accurate biomarker for prenatal androgen that can be readily measured in adults. Talk to the hand. Scientists try to debunk idea that finger length can reveal personality and health 2019-06-06T04:00:00Z Second, Brown’s team points to androgen receptor binding, a process key to neurodevelopment. DDT banned for decades may still be affecting autism risk 2018-09-20T04:00:00Z In humans, the most important male androgen is testosterone. Anatomy and Physiology 2013-06-19T00:00:00Z "This applies to any and all medical conditions which might be treated through use of androgens." USA Powerlifting organization bans transgender women from competing 2019-02-05T05:00:00Z Mutations of the AR gene or amplifications of DNA that increase the copies of sequence encoding AR might enable tumour cells to enhance AR-pathway signalling even when androgen levels are low7,8. Sequence of events in prostate cancer 2018-08-23T04:00:00Z "I don't know a more accurate biomarker for prenatal androgen that can be readily measured in adults," says neuroscientist Marc Breedlove of Michigan State University in East Lansing. Talk to the hand. Scientists try to debunk idea that finger length can reveal personality and health 2019-06-06T04:00:00Z A study in rats found that DDE inhibits androgen receptor binding, an outcome also seen in a rat model of autism. DDT banned for decades may still be affecting autism risk 2018-09-20T04:00:00Z DDT is also known to bind to proteins in the body called androgen receptors, which allow cells to respond to testosterone and other hormones. Autism and DDT: What One Million Pregnancies Can--and Can't--Reveal 2018-08-16T04:00:00Z "These advantages are not eliminated by reduction of serum androgens such as testosterone yielding a potential advantage in strength sports such as powerlifting." USA Powerlifting organization bans transgender women from competing 2019-02-05T05:00:00Z DDT is also known4 to bind to proteins in the body called androgen receptors, which allow cells to respond to testosterone and other hormones. Autism and DDT: What one million pregnancies can — and can’t — reveal 2018-08-15T04:00:00Z "I'm not saying androgen is not at all important for human behavior. It is," she says. Talk to the hand. Scientists try to debunk idea that finger length can reveal personality and health 2019-06-06T04:00:00Z The second measure is the number and sensitivity of androgen receptors, which vary significantly from person to person. Does testosterone make you mean? 2018-03-20T04:00:00Z Evolution Small peptides known as selective androgen receptor modulators, or SARMs, increase the sensitivity of muscle cells to natural steroid hormones—with fewer undesirable side effects than traditional steroids. The Scientific American Guide to Cheating in the Olympics 2017-12-05T05:00:00Z “It’s because we don’t have any sensitivity to androgens,” the culprit behind acne, one member of the group explained. The intersex rights movement is ready for its moment 2017-10-05T04:00:00Z This early start seems to be related to a rapid 'catch-up' of postnatal growth, with premature infants having higher circulating levels of androgens in early childhood. Puberty: Early starters : Nature : Nature Research 2017-10-03T04:00:00Z Prenatal exposure to different levels of androgen does seem to produce different effects throughout the life span. Google CEO caves in to the mob 2017-08-11T04:00:00Z The new study also found that female competitors with high levels of androgens benefit from improved visuospatial abilities. Caster Semenya could be forced to undertake hormone therapy for future Olympics 2017-07-03T04:00:00Z And men undergoing androgen therapy shouldn't stop the treatment based on these findings, the researchers said, because more studies are needed to verify this potential link. Can Hormonal Rx for Prostate Cancer Raise Dementia Risk? 2016-10-13T04:00:00Z They also appear to disrupt “androgen function,” or the way your body produces and uses the hormone testosterone, Patisaul says. 5 Things Wrong With Your Deodorant 2016-07-05T04:00:00Z When Chand’s results came in a few days later, the doctor said her “male hormone” levels were too high, meaning she produced more androgens, mostly testosterone, than most women did. The Humiliating Practice of Sex Testing Female Athletes 2016-06-28T04:00:00Z Instead they create an abnormal form of androgen receptor which is not linked to the growth of hormones and therefore does not respond to standard hormone treatment. New drugs for aggressive prostate cancer 'promising' - BBC News 2016-05-01T04:00:00Z Synthetic androgens: Androgens are the general class of hormones to which testosterone belongs. “Male contraceptive options haven’t changed since Elvis was thin”: These revolutionary alternatives to condoms are dragging male birth control into the 21st century 2016-04-21T04:00:00Z "In the brain, the ability of neurons to repair themselves and not die off, those are at least partially regulated by androgens," he said. Can Hormonal Rx for Prostate Cancer Raise Dementia Risk? 2016-10-13T04:00:00Z If a lion mother had abnormally high androgens during pregnancy, her female offspring may end up “masculinized”—a situation that occurs occasionally in people but which is rarely observed in wild animals. No, Those Aren't Male Lions Mating. One Is Likely a Female. 2016-04-18T04:00:00Z This is what the androgen normally attaches to, but with no receptor mechanism to interfere with, the drugs are powerless. Metastasis: Resistance fighters : Nature : Nature Publishing Group 2015-12-14T05:00:00Z For one thing, androgens appear to keep circulating levels of a protein called beta amyloid low in a person's bloodstream, said Keith Fargo, director of scientific programs and outreach for the Alzheimer's Association. Hormone Therapy for Prostate Cancer Tied to Possible Alzheimer's Risk 2015-12-07T05:00:00Z The ideal androgen and the ideal mode of administration are still being investigated. MENT is a promising synthetic androgen that is being developed as a subdermal implant. “Male contraceptive options haven’t changed since Elvis was thin”: These revolutionary alternatives to condoms are dragging male birth control into the 21st century 2016-04-21T04:00:00Z But, the picture might be more complex, with factors other than androgen therapy boosting dementia risk, said Heather Snyder, senior director of medical and scientific operations for the Alzheimer's Association. Can Hormonal Rx for Prostate Cancer Raise Dementia Risk? 2016-10-13T04:00:00Z Yet some of them were insensitive to androgens, which meant high level of testosterone wouldn’t help them. Win for Dutee Chand, but Line Between Male and Female Athletes Remains Blurred 2015-07-28T04:00:00Z However, the area of the androgen receptor that triggers the cell to divide, found at the protein's opposite end, still works. Metastasis: Resistance fighters : Nature : Nature Publishing Group 2015-12-14T05:00:00Z So, the researchers decided to investigate a possible association between androgen deprivation therapy and the degenerative neurological disease. Hormone Therapy for Prostate Cancer Tied to Possible Alzheimer's Risk 2015-12-07T05:00:00Z Some synthetic androgens suppress spermatogenesis at lower doses and with fewer side effects than testosterone. “Male contraceptive options haven’t changed since Elvis was thin”: These revolutionary alternatives to condoms are dragging male birth control into the 21st century 2016-04-21T04:00:00Z However, the military initially declined my request to receive the medically-mandated treatment for my diagnosed gender dysphoria, which is to live as a woman and receiving a regular regiment of estrogen and androgen blockers. The years since I was jailed for releasing the 'war diaries' have been a rollercoaster | Chelsea E Manning 2015-05-27T04:00:00Z I also discovered that less is often more with respect to androgen deprivation. This is what 25 years of castration terror looks like 2015-05-18T04:00:00Z Prostate cancer feeds on male hormones, which are called androgens and include the commonly known hormone testosterone. Can Statins Help Improve Prostate Cancer Survival? 2015-03-09T04:00:00Z Complete androgen insensitivity syndrome, or CAIS, for example, arises when a person's cells are deaf to male sex hormones, usually because the receptors that respond to the hormones are not working. Sex redefined 2015-02-17T05:00:00Z Those with an early cancer that is growing rapidly might do best with multiple treatment regimens such as surgery followed by radiation along with androgen deprivation therapy. Prostate Cancer Treatment: Surgery or Radiation? 2015-01-28T05:00:00Z However, a new, small study suggests that a treatment strategy called bipolar androgen therapy -- where patients alternate between low and high levels of testosterone -- might make prostate tumors more responsive to standard hormonal therapy. Strategy Might Thwart Resistance to a Common Prostate Cancer Treatment 2015-01-07T05:00:00Z Six to eight months of androgen blockade, then back to normal levels of testosterone for about a year and a half. This is what 25 years of castration terror looks like 2015-05-18T04:00:00Z By reducing cholesterol levels, statins might cause a reduction in available androgens by inadvertently robbing the body of a key building block for those hormones. Can Statins Help Improve Prostate Cancer Survival? 2015-03-09T04:00:00Z Hormone therapy, which suppresses male hormones called androgens, helps stop cancer cells from growing. Too Few Prostate Cancer Patients Get Bone-Strengthening Meds: Study 2014-12-02T05:00:00Z So, one common treatment, called androgen deprivation therapy, involves reducing a patient's levels of these hormones. Some Prostate Cancer Patients Might Safely Delay Hormonal Therapy: Study 2014-05-14T04:00:00Z "It needs to be stressed that bipolar androgen therapy is not ready for adoption into routine clinical practice, since these studies have not been completed," he said. Strategy Might Thwart Resistance to a Common Prostate Cancer Treatment 2015-01-07T05:00:00Z Eastman says that the results of testing, analysed by Thomas Osimitz of Science Strategies, a consulting firm in Charlottesville, Virginia, and his colleagues, verified that Tritan's monomers do not bind to oestrogen or androgen receptors. Toxicology: The plastics puzzle 2014-04-16T17:21:06.648Z Last year, a bioassay of this kind found androgens in 35% of freshwater samples tested, far more than chemical assays would suggest. Hormone Disruptors Rise from the Dead Like Zombies 2013-09-30T15:45:00.927Z Moreover, vasopressin receptor density itself depends on the presence of androgens, including testosterone. Touching a Nerve: Exploring the Implications of the Self as Brain, Part 2 [Excerpt] 2013-07-27T13:45:00.477Z Small but important correction: Once it passes from the blood into the brain, some testosterone is transformed by an enzyme into a more potent androgen, dihydrotestosterone. Touching a Nerve : Exploring the Implications of the Self as Brain, Part 1 [Excerpt] 2013-07-26T14:45:03.867Z For the study, 16 men with hormone therapy-resistant prostate cancer received bipolar androgen therapy. Strategy Might Thwart Resistance to a Common Prostate Cancer Treatment 2015-01-07T05:00:00Z If the finding is replicated in other studies, he said doctors should consider checking men's kidney function before prescribing androgen deprivation therapy. Prostate cancer hormonal therapy tied to kidney risks 2013-07-16T20:04:43Z Researchers analyzed health insurance claims for more than 10 million men aged 40 and over and found that by 2011, almost 3 percent were taking so-called androgen replacement therapy. More men treated for low T, some without evidence 2013-06-04T18:46:28Z Additionally, androgens stimulate the genes that express vasopressin itself. Touching a Nerve: Exploring the Implications of the Self as Brain, Part 2 [Excerpt] 2013-07-27T13:45:00.477Z But the latest marketing push by drugmakers is for easy-to-use gels and patches that are aimed at a much broader population of otherwise healthy older men with low testosterone, or androgen deficiency. Testosterone marketing frenzy draws skepticism 2012-09-09T18:46:04Z Along with her co-author Katrina Karkazis, of Stanford’s Center for Biomedical Ethics, she cites the fact that women who are unable to process androgens—including testosterone—tend to excel in sports, not fail at them. Olympics Gender Bender 2012-07-26T08:45:00Z In total, just over half of the men were taking androgen deprivation therapy. Prostate cancer hormonal therapy tied to kidney risks 2013-07-16T20:04:43Z In mice the digit ratio corresponds to the female-male hormonal balance in the womb during the week digits form; androgen apparently produces a longer ring finger. Fact Finder: Digit Divide 2012-06-30T14:15:00.223Z This usually results from a genetic abnormality that causes the adrenal glands to produce extra androgens. Touching a Nerve: Exploring the Implications of the Self as Brain, Part 2 [Excerpt] 2013-07-27T13:45:00.477Z Also in 2006, the Endocrine Society published the first physician guidelines for prescribing testosterone for men with androgen deficiency. Testosterone marketing frenzy draws skepticism 2012-09-09T18:46:04Z The new rules said that women with levels of testosterone that reach a man’s normal level will be barred from competing with other women if it is found that her body is responsive to androgens. Critics Say Olympic Sex-Verification Policy Is a Failure 2012-06-26T02:00:15Z Unlike current use, past use of androgen deprivation therapy was not tied to a higher risk of kidney injury, the study team wrote Tuesday in the Journal of the American Medical Association. Prostate cancer hormonal therapy tied to kidney risks 2013-07-16T20:04:43Z Fuxjager and his team discovered that winning a series of contests boosted the number of androgen receptors in a part of the brain that controls social aggression - this is the winner effect. The science of home advantage 2012-06-19T00:39:15Z The androgens fit into the receptors like a key into a lock. Touching a Nerve: Exploring the Implications of the Self as Brain, Part 2 [Excerpt] 2013-07-27T13:45:00.477Z Rasmussen & Murru3 studied androgen levels in a number of captive sharks over time. Mythbusting 101: bulking up with bull shark testosterone 2012-06-15T18:15:00.223Z Opt for these to get plenty of zinc, a mineral that helps regulate the production of androgens. 10 Best Foods for Your Hair 2012-06-14T14:50:00Z In particular, we observed clustering of androgen and oestrogen receptors in male samples and showed that androgen-receptor expression was associated with better overall survival. Perspective: Not just for women 2012-05-30T17:51:20.620Z Using enzymes and Y-shaped proteins called antibodies, the scientists analyzed the fecal extracts for levels of androgens—steroid hormones, such as testosterone, that promote male sexual behavior. In the Heat for a Moment: The Male Giant Panda's Sex Drive Fluctuates to Match the Female's Short-Lived Libido 2012-04-04T20:15:00.213Z In these conditions, the androgens cannot masculinize the brain or the body, despite the XY genetic makeup. Touching a Nerve: Exploring the Implications of the Self as Brain, Part 2 [Excerpt] 2013-07-27T13:45:00.477Z By binding specific 'ligands' -- hormones ranging from estrogens and androgens to cortisol - the receptors trigger "these remarkable cascades of biological activity during development and physiology," Thornton says. Biologist Resurrects Prehistoric Proteins 2012-03-21T20:15:00.223Z The Medivation drug, called an androgen receptor signaling inhibitor, works to blunt the effects of male hormones that spur tumor growth, Scher said. Medivation Surges on Prostate Cancer Drug: San Francisco Mover 2012-02-01T19:23:24Z One is that an excess of androgens caused by obesity provokes acne. Well Blog: Really? The Claim: Excess Weight Raises the Risk of Acne 2012-01-23T16:04:57Z But by the peak breeding season—March 22 to April 15—androgen levels had started to drop back down to baseline. In the Heat for a Moment: The Male Giant Panda's Sex Drive Fluctuates to Match the Female's Short-Lived Libido 2012-04-04T20:15:00.213Z In some genetic variants, the receptor lacks the right shape to allow the androgens to bind to it. Touching a Nerve: Exploring the Implications of the Self as Brain, Part 2 [Excerpt] 2013-07-27T13:45:00.477Z The studies included about 2,500 men that were treated with androgen deprivation therapy over anywhere from three months to indefinitely, and 2,300 that weren't. Prostate cancer hormonal therapy cuts deaths: report 2011-12-06T21:42:08Z The company calls this an androgen receptor signaling inhibitor. Prescriptions Blog: Prostate Cancer Drug Shows Promise in Study 2011-11-03T16:21:37Z While androgens, such as testosterone, are typically associated with male development, they are also present in women. Breast cancer prostate drug hope 2011-06-25T01:25:08Z "We will monitor for possible side effects of androgen therapy, which are acne, oiliness of skin or deepening of the voice," he e-mails later. Amortality: Young or Old, Why It's No Longer Necessary to Act Your Age 2011-06-11T17:33:50Z In other genetic variants, no receptor proteins are produced at all, so the androgen has nothing to bind to. Touching a Nerve: Exploring the Implications of the Self as Brain, Part 2 [Excerpt] 2013-07-27T13:45:00.477Z Why not accept different androgen levels as natural genetic variation? Women with High Male Hormone Levels Face Sports Ban 2011-04-14T20:45:00.267Z Testing levels for men and women differ because males naturally produce more androgens. IAAF introduce new gender rules 2011-04-12T12:16:17Z Dr Lesley Walker, from Cancer Research UK, said: "Prostate cancer depends on the androgen receptor for growth so it's a great surprise that a type of breast cancer might also be fuelled by this protein." Breast cancer prostate drug hope 2011-06-25T01:25:08Z Researchers believe that sharing the womb with a male twin might mean that females are exposed to greater amounts of predominantly male hormones, called androgens, than those without a male twin. Girls in girl-boy twin pairs may be a bit heavier 2011-03-18T21:29:22Z A male XY fetus may also carry the genetic defect, but in that case, the extra androgens are consistent with the male body and brain, and the condition may go unrecognized. Touching a Nerve: Exploring the Implications of the Self as Brain, Part 2 [Excerpt] 2013-07-27T13:45:00.477Z They have pinpointed it as the loss of a particular chunk of non-coding DNA that influences the expression of the androgen receptor gene involved in hormone signalling. How the Penis Lost Its Spikes 2011-03-09T23:45:05.407Z A female athlete will be permitted to compete in women's competition if their androgen levels are below the male range. IAAF introduce new gender rules 2011-04-12T12:16:17Z A number of environmental factors—including a mother’s smoking or obesity—appear able to perturb fetal androgen levels. Low Sperm Counts Linked to Fetal Effects 2011-03-04T15:35:00Z While the exact mechanism isn't know, experts suspect that the male hormones known as androgens may play a critical role in promoting both conditions. Early Balding is Linked to Prostate Cancer 2011-02-17T08:20:00Z It blocks the conversion of testosterone to an androgen hormone called dihydrotestosterone, which is thought to cause hair loss. Early balding linked to risk of prostate cancer 2011-02-16T00:27:30Z The scientists strongly recommended that all pesticides in use today be screened to check if they block testosterone and other androgens, the hormones critical to a healthy reproductive system for men and boys. Pesticides May Block Male Hormones 2011-02-15T18:15:05.270Z Pharmaceutical companies, too, are working on drugs called selective androgen receptor modulators, designed to increase muscle mass without the side effects of the hormones sometimes used now. The New Old Age: Strengthening Older Muscles 2011-01-18T17:00:45Z “AGD therefore offers a lifelong readout of fetal androgen exposure—and just for this critical period of vulnerability,” which he says roughly corresponds to weeks eight through 14 of human gestation. Low Sperm Counts Linked to Fetal Effects 2011-03-04T15:35:00Z Some experts believe that androgens are thought to protect against colorectal cancer, and possible side effects of the therapy include several conditions considered risk factors for the disease. Study: Treatment for prostate cancer may increase risk of colorectal cancer 2010-11-29T23:09:00Z In February, various doctors' groups wrote in the medical journal Circulation that they felt androgen deprivation treatment was likely to raise the risk of heart attack. FDA warns of prostate cancer drug risks 2010-10-21T00:45:00Z But this process wasn't perfect: It "failed" female athletes with androgen insensitivity syndrome, since their genes made them seem male. Athletic cases show line between male and female can be hazy 2009-10-20T04:00:00Z Three of the nine brain regions they looked at showed an increase in androgen receptors after the test dispute. 'Winner effect' linked to changes in brain circuitry 2010-07-17T00:55:00Z But there remained the nagging question of whether AGD provided a similarly important readout of androgen exposure in early human development. Low Sperm Counts Linked to Fetal Effects 2011-03-04T15:35:00Z "The androgen receptors in liver cells bind to this sequence and trigger a cascade of damage to liver tissue," they explained. Sex hormone explains higher liver cancer risk in men 2010-05-19T08:07:00Z It was reasonable to think, as many people did, that androgen receptors—which respond to male hormones—were mediating the manly transformation. Behaviour of the sexes: The hormone of laddishness 2010-04-29T11:22:00Z An advisory published in the American Heart Association's journal Circulation recommends that doctors keep a close eye on men they treat with so-called androgen deprivation therapy and help them avoid trading cancer for heart disease. 2010-02-01T21:22:00Z Animals with lower levels of androgen receptors displayed less winning behavior. 'Winner effect' linked to changes in brain circuitry 2010-07-17T00:55:00Z Tinkering with the receptors did not change overall androgen levels or leave any obvious toxic effects in the mice. Sex hormone explains higher liver cancer risk in men 2010-05-19T08:07:00Z Some of these were genetically modified to be lacking in androgen receptors in their livers. Sex hormone explains higher liver cancer risk in men 2010-05-19T08:07:00Z But androgen receptors were found to be nearly non-existent in the brains of newborn animals. Behaviour of the sexes: The hormone of laddishness 2010-04-29T11:22:00Z Without male hormone receptors to respond to testosterone, the researchers started to suspect androgen receptors were not the players they had been assumed to be. Behaviour of the sexes: The hormone of laddishness 2010-04-29T11:22:00Z In their study, published this week in Neuron, the researchers decided to look at male mice which had been genetically engineered to lack androgen receptors in their nervous systems. Behaviour of the sexes: The hormone of laddishness 2010-04-29T11:22:00Z These males still had androgen receptors in their muscles and elsewhere, so they had masculine bodies, and they experienced the testosterone surge and responded to normally circulating testosterone. Behaviour of the sexes: The hormone of laddishness 2010-04-29T11:22:00Z |
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