| 单词 | familial hypercholesterolemia |
| 例句 | In the human genetic disease familial hypercholesterolemia, the LDL receptors are defective or missing entirely. Biology for AP Courses 2022-06-09T00:00:00Z As evidence, she points to studies of people with familial hypercholesterolemia—a condition that arises from a mutation in the gene encoding the LDL receptor protein. Is There More to a Healthy-Heart Diet Than Cholesterol? 2021-12-02T05:00:00Z Riksen says some of the most direct evidence came from studying people with familial hypercholesterolemia, a genetic condition causing high levels of blood cholesterol. Immune Cells That Remember Inflammation Could Offer Treatment Targets for Atherosclerosis 2021-12-01T05:00:00Z To reduce the risk of stroke, as well as heart attack, some people with familial hypercholesterolemia are prescribed PCSK9 inhibitors to lower "bad" cholesterol. What to Do If You’re Denied Coverage for a New Cholesterol Drug You Need 2016-09-09T04:00:00Z The findings may help doctors explain the risks of familial hypercholesterolemia more clearly to patients. Inherited Cholesterol Disorder Significantly Boosts Heart Risks 2016-06-30T04:00:00Z The chain of events leading up to the current controversy began in late May, when AstraZeneca won approval of Crestor to treat children with the rare disease, homozygous familial hypercholesterolemia, or HoFH. AstraZeneca Pushes to Protect Crestor From Generic Competition 2016-06-27T04:00:00Z As a result, people with familial hypercholesterolemia have abnormally high levels of LDL cholesterol and, if left untreated, are up to 13 times more likely to develop coronary heart disease than someone without the mutation. Is There More to a Healthy-Heart Diet Than Cholesterol? 2021-12-02T05:00:00Z Estimates are that familial hypercholesterolemia affects between roughly 1 in 250 to 1 in 500 people. 1 in 5 Children Estimated to Have High – or Abnormally Low – Cholesterol 2016-02-09T05:00:00Z These include patients with the inherited condition familial hypercholesterolemia, which causes abnormally high levels of LDL, or atherosclerotic heart conditions. Need help paying for Amgen's Repatha? Get ready to give up your privacy 2015-11-13T05:00:00Z For others, statins just don't do the job -- including people with familial hypercholesterolemia, an inherited condition that causes very high LDL levels and heart attacks at an early age. FDA Approves Second Drug in New Class of Cholesterol-Lowering Medications 2015-08-27T04:00:00Z As it did with Praluent, the FDA approved Repatha to be taken with statin drugs, for patients with a hereditary condition called familial hypercholesterolemia or with coronary artery disease that requires additional lowering of cholesterol. FDA Approves Amgen’s Cholesterol-Lowering Drug Repatha 2015-08-27T04:00:00Z "I think the first patients to receive this drug will be those with familial hypercholesterolemia," Reed said, referring to a genetic condition that causes very high LDL levels that often resist statin treatment. Can U.S. Health-Care System Afford New, Improved Cholesterol Drugs? 2015-06-18T04:00:00Z The committee unanimously agreed that Amgen’s drug should be approved for people with a rare genetic disorder, homozygous familial hypercholesterolemia, because of their dire need for treatments. Panel Tells F.D.A. to Back Second Drug to Help Heart 2015-06-10T04:00:00Z In particular, that includes individuals with a genetic condition called familial hypercholesterolemia, which is characterized by strikingly high cholesterol levels. Nonstatin Cholesterol-Lowering Drugs Show Promise 2015-05-14T04:00:00Z In children with familial hypercholesterolemia, atherosclerosis progression begins before puberty, so guidelines recommend that they begin taking statins as young as age 8. Statins May Help Kids With Genetic Cholesterol Disorder 2014-09-09T04:00:00Z The RUTHERFORD-2 study included patients with familial hypercholesterolemia, an inherited condition that causes high levels of "bad" LDL cholesterol starting at birth. Amgen's cholesterol fighter succeeds in fifth late-stage study 2014-01-30T22:45:17Z The drug was approved in December 2012 to help further lower cholesterol in patients with homozygous familial hypercholesterolemia. Justice Department Investigating Aegerion Over Marketing Of New Cholesterol Drug 2014-01-10T03:27:00Z This is the very worst form of a genetic disorder called familial hypercholesterolemia. For Isis CEO, A Victory After 24 Years Of Battle 2013-01-30T11:40:39Z These are the first drugs specifically developed and approved for familial hypercholesterolemia. FDA Approves Mipomersen For Homozygous Familial Hypercholesterolemia 2013-01-30T00:04:49Z "Early initiation of statins to children with familial hypercholesterolemia showed significant improvement...," said Dr. Shahed Querichi, director of pediatric cardiology at Staten Island University Hospital, in New York City. Statins May Help Kids With Genetic Cholesterol Disorder 2014-09-09T04:00:00Z The disorder, called familial hypercholesterolemia, is a genetic disease that results in elevated bad cholesterol levels and increased risk of premature heart disease. FDA reviewers spot safety concerns with Sanofi, Isis lipid drug 2012-10-16T18:53:12Z Some people develop extremely high LDL levels because of a genetic disease called familial hypercholesterolemia that severely limits their ability to clear cholesterol from their blood. Cholesterol Conundrum 2011-10-25T15:15:00.250Z Patients with familial hypercholesterolemia are unable to properly metabolize LDL due to dysfunctional LDL receptors. Safety is key for upcoming Isis cholesterol data 2010-08-01T16:34:00Z Clinicians were therefore eager to see the results of a 2008 study named ENHANCE, which compared a combination of ezetimibe and one particular statin drug, simvastatin, against simvastatin alone in people with familial hypercholesterolemia. Cholesterol Conundrum 2011-10-25T15:15:00.250Z |
| 随便看 |
英语例句辞典收录了117811条英语例句在线翻译词条，基本涵盖了全部常用单词及词组的例句翻译及用法，是英语学习的有利工具。