英语词汇“ex vivo”造句的方法、技巧、例句及翻译-英语例句辞典

The machines pump oxygen and nutrients through the lungs and keep them warm—a process called ex vivo lung perfusion. No One Should Die Waiting for an Organ Transplant. These Doctors Want to Ensure That Doesn’t Happen 2023-10-19T04:00:00Z

One early-phase clinical trial employed an ex vivo gene-editing method to treat people with sickle cell disease or with a related blood disorder called beta thalassemia. The Definition of Gene Therapy Has Changed 2021-10-19T04:00:00Z

After this step, called “ex vivo” because a patient’s cells are treated outside the body, doctors infuse the cells back into the person. Gene therapy trials for sickle cell disease halted after two patients develop cancer 2021-02-16T05:00:00Z

The method revived lungs that ex vivo lung perfusion, the normal method of maintaining and repairing lungs outside the body, had failed to fix. Daily briefing: How Vietnam managed zero deaths from coronavirus 2020-07-13T04:00:00Z

This ex vivo approach is unlikely to correct many genetic conditions. Manage risk of accidental gene editing of germline 2019-04-22T04:00:00Z

One method of testing cancer therapies, including glioblastomas, has been so-called “ex vivo” cancer models, in which malignant cells are probed in the lab. New Strategies Take On the Worst Cancer--Glioblastoma 2019-03-27T04:00:00Z

Once, he rightly questioned the clinical validity of an ex vivo cardiovascular model that flushed fluid through the heart in the opposite direction of blood flow. The Widening Chasm between Research and Clinical Practice 2018-11-30T05:00:00Z

In past small clinical trials, several boys with an inherited immune disorder who received similar ex vivo gene therapy developed leukemia. Gene therapy trials for sickle cell disease halted after two patients develop cancer 2021-02-16T05:00:00Z

For both of these trials, the gene editing is done ex vivo — meaning outside the patient’s body. Perspective | Here’s what we know about CRISPR safety – and reports of ‘genome vandalism’ 2018-08-31T04:00:00Z

That treatment is known as “ex vivo” because it involves editing a patient’s blood cells in a dish, then putting the cells back into the patient. Gene edited monkeys offer hope for heart disease patients 2018-07-09T04:00:00Z

Nader Sanai, a neurosurgeon specializing in cancer of the brain at the Barrow Neurologic Institute in Phoenix, is supportive of ex vivo modeling research. New Strategies Take On the Worst Cancer--Glioblastoma 2019-03-27T04:00:00Z

By contrast, pharmacological inhibition of the cell cycle increased artery formation in an ex vivo experiment. Coronary artery development, one cell at a time 2018-07-03T04:00:00Z

Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites. Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors 2017-11-28T05:00:00Z

Amyloid is defined pathologically by the demonstration of green birefringence on binding of the dye Congo red and biophysically by a cross-β fibre diffraction pattern. b, Models of recombinant PrP fibrils and ex vivo prions. Mammalian prions and their wider relevance in neurodegenerative diseases : Nature : Nature Research 2016-11-08T05:00:00Z

To fulfil these predictions, ex vivo genetic modification and culturing of HSCs and their progenitors must become more robust and reliable. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z

A report on new research technology published recently in the journal Nature Biomedical Engineering may address the limitations of previous ex vivo approaches. New Strategies Take On the Worst Cancer--Glioblastoma 2019-03-27T04:00:00Z

Enrichment analysis of consensus markers reinforced the primacy of peritoneal macrophage infiltration and activation, which was demonstrably elevated in ex vivo cultures. [Research Articles] Molecular Network Analysis of Endometriosis Reveals a Role for c-Jun-Regulated Macrophage Activation 2014-02-05T19:55:05.837Z

CD8 T cell lines specific for these phosphopeptides recognized and killed both leukemia cell lines and human leukocyte antigen–matched primary leukemia cells ex vivo. [Research Articles] MHC Class I-Associated Phosphopeptides Are the Targets of Memory-like Immunity in Leukemia 2013-09-18T18:55:08.247Z

HSC gene therapy is administered by ex vivo gene transfer into haematopoietic progenitors. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z

The new report of a chip from researchers in South Korea may represent the most advanced ex vivo model of a glioblastoma to date. New Strategies Take On the Worst Cancer--Glioblastoma 2019-03-27T04:00:00Z

This study aimed to validate the technique by applying it to the analysis of fresh human tissue samples ex vivo and to demonstrate the translation to real-time use in vivo in a surgical environment. [Research Articles] Intraoperative Tissue Identification Using Rapid Evaporative Ionization Mass Spectrometry 2013-07-17T18:55:09.017Z

Notably, the peptides’ immune boosting capacity helped to rescue proinflammatory responses of immunosuppressed sepsis patients ex vivo. [Research Articles] Targeting the TLR Co-Receptor CD14 with TLR2-Derived Peptides Modulates Immune Responses to Pathogens 2013-05-15T18:55:06.783Z

The systematic production of high-titre prions from rPrP therefore probably requires a detailed knowledge of the quaternary structure of authentic ex vivo prions. Mammalian prions and their wider relevance in neurodegenerative diseases : Nature : Nature Research 2016-11-08T05:00:00Z

This depletes endogenous progenitors and differentiated cells in the bone marrow — as well as the lymphoid organs, in some cases — and favours engraftment of the ex vivo gene-corrected cells. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z

Sanai laments that while ex vivo models of other cancer types can be fairly faithful representations of their human counterpart, this just isn’t true for glioblastoma. New Strategies Take On the Worst Cancer--Glioblastoma 2019-03-27T04:00:00Z

We first applied the peptide ex vivo to esophageal specimens from 17 patients to validate specific binding. [Research Articles] Targeted Imaging of Esophageal Neoplasia with a Fluorescently Labeled Peptide: First-in-Human Results 2013-05-08T18:55:08.117Z

In addition, ex vivo treatment of human skin averted the disease-related shift from quiescent to effector T cell phenotype. [Research Articles] Mutant HSP70 Reverses Autoimmune Depigmentation in Vitiligo 2013-02-27T19:25:08.233Z

This feature is not reflected in the image presented by Catani ., but is reflected in our images, presumably owing to improved technical characteristics ex vivo. [Technical Response] Response to Comment on “The Geometric Structure of the Brain Fiber Pathways” 2012-09-27T17:55:32.233Z

T cells are also popular targets for ex vivo gene therapy. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z

We analyzed the movements of nanoparticles of various diameters and surface coatings within fresh human and rat brain tissue ex vivo and mouse brain in vivo. [Research Articles] A Dense Poly(Ethylene Glycol) Coating Improves Penetration of Large Polymeric Nanoparticles Within Brain Tissue 2012-08-29T19:25:11.930Z

When mixed with human blood ex vivo, oxygen transfer from 70 volume % microparticles was complete within 4 s. [Research Articles] Oxygen Gas-Filled Microparticles Provide Intravenous Oxygen Delivery 2012-06-27T18:55:14.913Z

Here, we report on the ex vivo detection of 2HG in -mutated tissue samples from patients with recurrent low-grade gliomas using the nuclear magnetic resonance technique of proton high-resolution magic angle spinning spectroscopy. [Research Articles] Magnetic Resonance of 2-Hydroxyglutarate in IDH1-Mutated Low-Grade Gliomas 2012-01-11T20:25:08.257Z

We show that the resolution for tissue microstructure in our ex vivo experiments is approximately threefold higher than the in vivo studies compared. [Technical Response] Response to Comment on “The Geometric Structure of the Brain Fiber Pathways” 2012-09-27T17:55:32.233Z

Using in vitro and ex vivo models of vessel wall stiffness and aging, we show that stiffening of extracellular matrix within the intima promotes endothelial cell permeability—a hallmark of atherogenesis. [Research Articles] Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration 2011-12-07T19:55:09.007Z

These data establish a method for the ex vivo generation of graft-reactive, functional mouse and human T that uses a clinically approved agent, making pharmacological PDE inhibition a potential strategy for T-based therapies. [Research Articles] Functional Regulatory T Cells Produced by Inhibiting Cyclic Nucleotide Phosphodiesterase Type 3 Prevent Allograft Rejection 2011-05-18T19:25:13.117Z

Both he and Dr. Kato likened ex vivo operations to the early days of liver transplants, which originally took twice as long as they do now and met with harsh criticism. In Surgery, a Tangled Tumor Meets Its Match 2009-12-16T19:00:00Z

Relative 2HG levels from pathologically confirmed mutant tissues correlated with levels of other ex vivo metabolites and histopathology parameters associated with increases in mitotic activity, relative tumor content, and cellularity. [Research Articles] Magnetic Resonance of 2-Hydroxyglutarate in IDH1-Mutated Low-Grade Gliomas 2012-01-11T20:25:08.257Z

Dr. Emond said he expected the team in New York to continue performing ex vivo operations, even though health care “bean counters will be appalled at our profligate ways.” Cancer Patient Dies Four Months After Daring Operation 2010-04-26T20:50:00Z

We have seen the truth of the maxim "Omne vivum ex vivo," and therefore that all particular forms of life are differentiations of the one Basic Life. The Law and the Word

He said ex vivo surgery was still in its early days, and the team hoped to improve it to help patients like Mr. Collison. Cancer Patient Dies Four Months After Daring Operation 2010-04-26T20:50:00Z

单词	ex vivo
例句	ex vivo The machines pump oxygen and nutrients through the lungs and keep them warm—a process called ex vivo lung perfusion. No One Should Die Waiting for an Organ Transplant. These Doctors Want to Ensure That Doesn’t Happen 2023-10-19T04:00:00Z One early-phase clinical trial employed an ex vivo gene-editing method to treat people with sickle cell disease or with a related blood disorder called beta thalassemia. The Definition of Gene Therapy Has Changed 2021-10-19T04:00:00Z After this step, called “ex vivo” because a patient’s cells are treated outside the body, doctors infuse the cells back into the person. Gene therapy trials for sickle cell disease halted after two patients develop cancer 2021-02-16T05:00:00Z The method revived lungs that ex vivo lung perfusion, the normal method of maintaining and repairing lungs outside the body, had failed to fix. Daily briefing: How Vietnam managed zero deaths from coronavirus 2020-07-13T04:00:00Z This ex vivo approach is unlikely to correct many genetic conditions. Manage risk of accidental gene editing of germline 2019-04-22T04:00:00Z One method of testing cancer therapies, including glioblastomas, has been so-called “ex vivo” cancer models, in which malignant cells are probed in the lab. New Strategies Take On the Worst Cancer--Glioblastoma 2019-03-27T04:00:00Z Once, he rightly questioned the clinical validity of an ex vivo cardiovascular model that flushed fluid through the heart in the opposite direction of blood flow. The Widening Chasm between Research and Clinical Practice 2018-11-30T05:00:00Z In past small clinical trials, several boys with an inherited immune disorder who received similar ex vivo gene therapy developed leukemia. Gene therapy trials for sickle cell disease halted after two patients develop cancer 2021-02-16T05:00:00Z For both of these trials, the gene editing is done ex vivo — meaning outside the patient’s body. Perspective \| Here’s what we know about CRISPR safety – and reports of ‘genome vandalism’ 2018-08-31T04:00:00Z That treatment is known as “ex vivo” because it involves editing a patient’s blood cells in a dish, then putting the cells back into the patient. Gene edited monkeys offer hope for heart disease patients 2018-07-09T04:00:00Z Nader Sanai, a neurosurgeon specializing in cancer of the brain at the Barrow Neurologic Institute in Phoenix, is supportive of ex vivo modeling research. New Strategies Take On the Worst Cancer--Glioblastoma 2019-03-27T04:00:00Z By contrast, pharmacological inhibition of the cell cycle increased artery formation in an ex vivo experiment. Coronary artery development, one cell at a time 2018-07-03T04:00:00Z Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites. Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors 2017-11-28T05:00:00Z Amyloid is defined pathologically by the demonstration of green birefringence on binding of the dye Congo red and biophysically by a cross-β fibre diffraction pattern. b, Models of recombinant PrP fibrils and ex vivo prions. Mammalian prions and their wider relevance in neurodegenerative diseases : Nature : Nature Research 2016-11-08T05:00:00Z To fulfil these predictions, ex vivo genetic modification and culturing of HSCs and their progenitors must become more robust and reliable. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z A report on new research technology published recently in the journal Nature Biomedical Engineering may address the limitations of previous ex vivo approaches. New Strategies Take On the Worst Cancer--Glioblastoma 2019-03-27T04:00:00Z Enrichment analysis of consensus markers reinforced the primacy of peritoneal macrophage infiltration and activation, which was demonstrably elevated in ex vivo cultures. [Research Articles] Molecular Network Analysis of Endometriosis Reveals a Role for c-Jun-Regulated Macrophage Activation 2014-02-05T19:55:05.837Z CD8 T cell lines specific for these phosphopeptides recognized and killed both leukemia cell lines and human leukocyte antigen–matched primary leukemia cells ex vivo. [Research Articles] MHC Class I-Associated Phosphopeptides Are the Targets of Memory-like Immunity in Leukemia 2013-09-18T18:55:08.247Z Amyloid is defined pathologically by the demonstration of green birefringence on binding of the dye Congo red and biophysically by a cross-β fibre diffraction pattern. b, Models of recombinant PrP fibrils and ex vivo prions. Mammalian prions and their wider relevance in neurodegenerative diseases : Nature : Nature Research 2016-11-08T05:00:00Z HSC gene therapy is administered by ex vivo gene transfer into haematopoietic progenitors. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z The new report of a chip from researchers in South Korea may represent the most advanced ex vivo model of a glioblastoma to date. New Strategies Take On the Worst Cancer--Glioblastoma 2019-03-27T04:00:00Z This study aimed to validate the technique by applying it to the analysis of fresh human tissue samples ex vivo and to demonstrate the translation to real-time use in vivo in a surgical environment. [Research Articles] Intraoperative Tissue Identification Using Rapid Evaporative Ionization Mass Spectrometry 2013-07-17T18:55:09.017Z Notably, the peptides’ immune boosting capacity helped to rescue proinflammatory responses of immunosuppressed sepsis patients ex vivo. [Research Articles] Targeting the TLR Co-Receptor CD14 with TLR2-Derived Peptides Modulates Immune Responses to Pathogens 2013-05-15T18:55:06.783Z The systematic production of high-titre prions from rPrP therefore probably requires a detailed knowledge of the quaternary structure of authentic ex vivo prions. Mammalian prions and their wider relevance in neurodegenerative diseases : Nature : Nature Research 2016-11-08T05:00:00Z This depletes endogenous progenitors and differentiated cells in the bone marrow — as well as the lymphoid organs, in some cases — and favours engraftment of the ex vivo gene-corrected cells. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z Sanai laments that while ex vivo models of other cancer types can be fairly faithful representations of their human counterpart, this just isn’t true for glioblastoma. New Strategies Take On the Worst Cancer--Glioblastoma 2019-03-27T04:00:00Z We first applied the peptide ex vivo to esophageal specimens from 17 patients to validate specific binding. [Research Articles] Targeted Imaging of Esophageal Neoplasia with a Fluorescently Labeled Peptide: First-in-Human Results 2013-05-08T18:55:08.117Z In addition, ex vivo treatment of human skin averted the disease-related shift from quiescent to effector T cell phenotype. [Research Articles] Mutant HSP70 Reverses Autoimmune Depigmentation in Vitiligo 2013-02-27T19:25:08.233Z This feature is not reflected in the image presented by Catani ., but is reflected in our images, presumably owing to improved technical characteristics ex vivo. [Technical Response] Response to Comment on “The Geometric Structure of the Brain Fiber Pathways” 2012-09-27T17:55:32.233Z T cells are also popular targets for ex vivo gene therapy. Gene therapy returns to centre stage : Nature : Nature Publishing Group 2015-10-13T04:00:00Z We analyzed the movements of nanoparticles of various diameters and surface coatings within fresh human and rat brain tissue ex vivo and mouse brain in vivo. [Research Articles] A Dense Poly(Ethylene Glycol) Coating Improves Penetration of Large Polymeric Nanoparticles Within Brain Tissue 2012-08-29T19:25:11.930Z When mixed with human blood ex vivo, oxygen transfer from 70 volume % microparticles was complete within 4 s. [Research Articles] Oxygen Gas-Filled Microparticles Provide Intravenous Oxygen Delivery 2012-06-27T18:55:14.913Z Here, we report on the ex vivo detection of 2HG in -mutated tissue samples from patients with recurrent low-grade gliomas using the nuclear magnetic resonance technique of proton high-resolution magic angle spinning spectroscopy. [Research Articles] Magnetic Resonance of 2-Hydroxyglutarate in IDH1-Mutated Low-Grade Gliomas 2012-01-11T20:25:08.257Z We show that the resolution for tissue microstructure in our ex vivo experiments is approximately threefold higher than the in vivo studies compared. [Technical Response] Response to Comment on “The Geometric Structure of the Brain Fiber Pathways” 2012-09-27T17:55:32.233Z Using in vitro and ex vivo models of vessel wall stiffness and aging, we show that stiffening of extracellular matrix within the intima promotes endothelial cell permeability—a hallmark of atherogenesis. [Research Articles] Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration 2011-12-07T19:55:09.007Z These data establish a method for the ex vivo generation of graft-reactive, functional mouse and human T that uses a clinically approved agent, making pharmacological PDE inhibition a potential strategy for T-based therapies. [Research Articles] Functional Regulatory T Cells Produced by Inhibiting Cyclic Nucleotide Phosphodiesterase Type 3 Prevent Allograft Rejection 2011-05-18T19:25:13.117Z Both he and Dr. Kato likened ex vivo operations to the early days of liver transplants, which originally took twice as long as they do now and met with harsh criticism. In Surgery, a Tangled Tumor Meets Its Match 2009-12-16T19:00:00Z Relative 2HG levels from pathologically confirmed mutant tissues correlated with levels of other ex vivo metabolites and histopathology parameters associated with increases in mitotic activity, relative tumor content, and cellularity. [Research Articles] Magnetic Resonance of 2-Hydroxyglutarate in IDH1-Mutated Low-Grade Gliomas 2012-01-11T20:25:08.257Z Dr. Emond said he expected the team in New York to continue performing ex vivo operations, even though health care “bean counters will be appalled at our profligate ways.” Cancer Patient Dies Four Months After Daring Operation 2010-04-26T20:50:00Z We have seen the truth of the maxim "Omne vivum ex vivo," and therefore that all particular forms of life are differentiations of the one Basic Life. The Law and the Word He said ex vivo surgery was still in its early days, and the team hoped to improve it to help patients like Mr. Collison. Cancer Patient Dies Four Months After Daring Operation 2010-04-26T20:50:00Z
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