| 单词 | enhancer |
| 例句 | Their high cheekbones shimmered with silver fae dust, a magic enhancer, and their long purple hair flowed in shiny waves. Witchlings 2022-04-05T00:00:00Z There is a breakdown in the supply chain for the performance enhancers. Pedaling Uphill, on a Bike and in a Marriage 2018-06-18T04:00:00Z I didn't care at all about the morality, or otherwise, of taking brain enhancers. The drugs do work: my life on brain enhancers 2013-05-03T22:00:00Z Installers are typically the ones who apply sealers and color enhancers after the stone is installed. Restoring the color to slate that’s lost its blackness 2019-09-13T04:00:00Z Penton’s signature bone broth relies on pork and/or chicken and enhancers including fennel, lemon and sherry vinegar. Hälsa in Brookland, previewed 2015-01-29T05:00:00Z Despite the enhancers, the citrus-“cooked” fish lacks the sparkle of a model ceviche. Review | Peruvian classics drowned out by a heaping side of noise 2018-09-27T04:00:00Z American wines are very bad and very expensive.15 to 17 degres alcohol kills the food and any taste.They add many different taste enhancers... Want to Pick Better Bottles? Repeat After Me: Wine Is Food 2017-03-06T05:00:00Z Ms. Acra’s cannier clients view such collaborations as potential image enhancers. For Hollywood Actresses, a Custom Dress on the Red Carpet Shows Fashion Clout 2014-01-11T00:36:27Z There's a whole world of plant-based flavor enhancers. 4 simple tips to embolden your home cooking, gleaned from Andrea Nguyen's “Ever-Green Vietnamese” 2023-03-28T04:00:00Z Instead of looking at each table as if a price tag were attached, he prefers to view seating as a social enhancer. Perspective | The latest trend I loathe in restaurants: No space between tables 2017-06-12T04:00:00Z Sleep may be a performance enhancer, but it’s an inefficient one. How a good night's sleep became the ultimate status symbol 2016-06-01T04:00:00Z The kitchen employs the enhancer with the restraint of a straitjacket. China Chilcano review: Strap in for a fun, but bumpy, ride from José Andrés 2015-03-24T04:00:00Z Ms. Stewart’s smooth, glowing complexion has spurred the widespread assumption that photo and video appearance enhancers — filters, as they’re known — were employed to alter her face in the Clé de Peau videos. Martha Stewart Welcomes You to Generation Ageless 2022-04-28T04:00:00Z And crucial to this task was the discovery by Orkin and colleagues that a small piece of the BCL11A gene, called the enhancer, controls foetal haemoglobin expression. Gene therapy offers hope for treatment of sickle cell anaemia 2016-10-01T04:00:00Z The typical amounts of vodka and heavy cream are reduced; because the liquor doesn’t cook for very long, you become aware of its role as a flavor enhancer. How this vodka cream sauce does more with less 2016-12-19T05:00:00Z The best career enhancer, she advised, is not a fashion campaign but playing a “crazy person” or starring in an indie. Golden Globes Alert: Seeking the Next Young Actress to Reign in Red Carpet Fashions 2012-01-04T22:13:35Z Taste the sauce: It should be a little sweet; the vodka acts as a flavor enhancer and doesn’t really evaporate. How this vodka cream sauce does more with less 2016-12-19T05:00:00Z It’s sweet/salty/nutty flavor is an undeniable flavor enhancer to so many savory dishes. A 5-ingredient lemon pasta with just one caveat 2018-08-05T04:00:00Z Sonic effects didn’t seem detached from what was happening onstage, a vision of the pit as its own private world of hermetic beauties; instead, the orchestra acted as an enhancer and interlocutor. Review: William Kentridge’s Triumphant ‘Wozzeck’ Will Come to the Met Opera 2017-08-09T04:00:00Z The next day, recipients encounter a meaty porridge, its bowl ringed with spoonfuls of fresh mint, ginger, clarified butter and other enhancers, allowing diners to season according to taste. Review | Punjab Grill is a feast for all the senses 2019-04-11T04:00:00Z It has been banned by most professional sports leagues in the US and by the International Olympic Committee, since some athletes use it as a performance enhancer. A 'miracle' healing gel, a cult-like following, and a fiercely protected empire 2019-05-01T04:00:00Z “It’s the underappreciated enhancer and my most favorite food attribute,” she says. The one food texture that makes me happiest 2016-01-15T05:00:00Z Bet you can’t eat just one of the chips, stippled with avocado-lime sauce and an enhancer of cashews, lemon and bell pepper. Tom Sietsema’s 8 favorite places to eat right now 2019-08-20T04:00:00Z Maybe Lance Armstrong needs performance enhancers to keep the lights on at ESPN, but come on, a guy has to do what he can to keep his job. The 12 Best “This Is SportsCenter” Spots as Chosen by TIME and ESPN 2013-11-21T17:49:54Z Suffice it to say, the grace note coaxed from soy sauce, Thai basil, sriracha, rice vinegar and other enhancers does wonders for whatever it touches. Conosci review: Michael Schlow’s crudo concept is a hidden gem 2016-05-31T04:00:00Z Richardson specified in a separate tweet that THC is not a performance enhancer. Sha’Carri Richardson, Tara Lipinski, Johnny Weir and others push back at doping decision leniency 2022-02-17T05:00:00Z Glutamate, an amino acid naturally found in food, is a flavour enhancer in cooking. A gourmet revival for St. Lawrence River marine algae 2022-09-11T04:00:00Z Photograph: Sophia Evans for the Observer Like cosmetic surgery, developed out of procedures for wounded soldiers, egg freezing has shifted from medical treatment to life enhancer, with the bin bag of ethical dilemmas that entails. We need to talk about egg freezing 2016-02-07T05:00:00Z Many people sneer at flavor enhancers, but this is fried chicken; no point in getting snobby. Self-protective cooking for a judgemental mother requires this recipe 2018-06-24T04:00:00Z Mascara, eyeliner, eyebrow enhancers, false lashes and eye shadow are a bright spot for beauty. A New Look for a New World 2021-12-09T05:00:00Z Asked to suggest military priorities for brain research, the US National Research Council pressed for the development of improved cognitive enhancers to add to the existing drugs. Mind Wars by Jonathan D Moreno – review 2012-06-01T21:55:07Z In contrast, the liver kebab is a hit — crusty, tender and accompanied by enhancers of minced garlic, cayenne, paprika and cumin. At Mazagan, a glimpse of modern Morocco Char is a trending flavor enhancer at restaurants and in processed foods, but home cooks often end up burning foods instead. Feel the char, not the burn: It heightens flavors, and here’s how to do it right 2018-10-05T04:00:00Z The chef hopes to bottle some of his enhancers and make them available for purchase this summer. Review | Cane doubles the pleasures with chef-driven Caribbean cooking 2019-06-12T04:00:00Z Buy stone color enhancer, which is sold along with masonry supplies in home centers and building-materials dealers. Be wary of a ‘leather finish’ on granite 2019-08-09T04:00:00Z Still, drinking remains less a performance enhancer than a byproduct of the game’s inherently social character. City Dwellers With Time to Kill 2011-05-20T22:16:28Z In the last year or two, Dr. Kunin said, enhancers that promote “eyebrow and eyelash growth have become booming business.” Skin Deep: After Overplucking, It?s Time to Call the Professionals 2009-12-17T06:12:47Z What they’re tasting, he says, is “the essence” of sopressata, from an oil he infuses with fennel seeds, garlic and other enhancers. At Modena, excellent Italian cooking is primed to ‘make a splash’ 2019-09-26T04:00:00Z Fried rice will also often contain soy sauce or other flavour enhancers, so treat with caution. How to order a healthier Chinese takeaway: swap noodles for rice and avoid the soup 2018-03-13T04:00:00Z “It’s like MSG,” Tseng says, with a smile that seems to acknowledge monosodium glutamate’s controversial role as a flavor enhancer. Confirmed: Sherry makes food taste better 2015-08-02T04:00:00Z Food technologists, who know MSG as a “salivation enhancer” and “flavour potentiator”, are fully aware of its prodigious ability to modulate our perception of otherwise humdrum ingredients. Chinese restaurant syndrome: has MSG been unfairly demonised? 2018-05-21T04:00:00Z Sleep, she says, is the ultimate performance enhancer. How a good night's sleep became the ultimate status symbol 2016-06-01T04:00:00Z SAM has been supplanted by MULE, a “material unit life enhancer,” and within months of its arrival Construction Robotics has moved an impressive 75 MULEs at $73,000 a pop. A Team of Engineers Invented a Brick-Laying Robot. This Is Their Story. 2020-01-07T05:00:00Z “Adding a lash enhancer would feel like cheating.” Skin Deep: Batter Up: Eyelashes Enjoy a Spike 2010-12-29T19:52:53Z If the Times searched its own archives, it would see several earlier periods of promotion of speed as a cognitive enhancer and study aid, followed by hysteria over psychosis and addictions. Getting prescription meds right 2013-02-18T16:00:00Z When reached by phone at his home in California, he explained to me that he doesn’t think of it as a performance enhancer so much as a “life enhancer.” These famous athletes are advocating for marijuana as a workout tool 2016-03-01T05:00:00Z The menu sets us up for finger licking by detailing crushed peanuts and sriracha aioli as enhancers, but the reality is a frequently dry and not very meaty mess. Review | Bar Charley has grown up. Now, you’ll dine as well as you drink. 2019-11-05T05:00:00Z This make-ahead version relies on a base of caramelized red onion, with nutritional yeast as an optional umami enhancer to add nuance and depth. A Beginner’s Thanksgiving: 7 Recipes That Lighten the Workload 2021-11-15T05:00:00Z A reader in the UK writes that when his wife was dying of breast cancer, “I purchased a vaporiser for her, it quickly became invaluable for both pain relief and as a mood enhancer”. Is marijuana a medical miracle? The truth is, we still don't know 2018-01-15T05:00:00Z The signature nigiri are sold by the piece and keep the focus on the fish while slipping in a pleasant enhancer or two. Review | Big and beautiful, D.C.’s newest Japanese restaurant masters the grill 2018-08-01T04:00:00Z Yet McCain learned relatively early in his political career that good press relations could be more than just a career enhancer: It could save his entire career. John McCain knew how to make journalists love him 2018-08-27T04:00:00Z If you're pining for something sweet but with a little extra tang, these vitamin C-packed bites are exceptional as a late afternoon pick-me-up or simply an oatmeal or granola enhancer. 10 budget-friendly Costco products with cult followings 2022-03-29T04:00:00Z A new study published in the International Society for Sexual Medicine examined eight of today’s most popular mood enhancers to answer the question. Which of these 8 so-called aphrodisiacs is the real deal? 2015-08-18T04:00:00Z The most common are used in sushi, salads, soups, even in desserts or as seasoning and flavour enhancers. A gourmet revival for St. Lawrence River marine algae 2022-09-11T04:00:00Z Sliced flank steak sponges the heat of the curry paste in which it’s stir-fried, along with eggplant and such tropical enhancers as lemongrass and lime leaves. Review | These three restaurants can help you keep date night on your to-do list 2020-08-20T04:00:00Z While I don't question the sanity of the millions of people who believe open air is a natural flavor enhancer, my side in the discourse remains firmly on the in side. Meet me inside — I hate eating al fresco 2022-07-03T04:00:00Z A garlicky all-purpose flavor enhancer, it is, as its name suggests, ideal for dipping crunchy fried things. 20 Simple Sauces That Will Transform Any Meal 2021-07-12T04:00:00Z June S.: MSG, also known as monosodium glutamate, is a flavor enhancer that is used in a number of Chinese dishes, soups and processed meats. Perspective | Hints From Heloise: The best gift 2019-03-14T04:00:00Z Indeed, Martino’s beer enhancers are also useful for customizing a pint of craft beer. Can a simple tea bag turn Coors Light into something worth drinking? 2015-05-10T04:00:00Z B. Coffee has been ruled a legal performance enhancer for Olympic swimmers. Style Invitational Week 1168: Asterisky business — give us nerdy humor 2016-03-24T04:00:00Z And what does a “material unit life enhancer” do? A Team of Engineers Invented a Brick-Laying Robot. This Is Their Story. 2020-01-07T05:00:00Z Generally, “natural” on a food label means no artificial preservatives, coloring or flavor enhancers were used on the item. Perspective | Hints From Heloise: Can banana aging be foiled? 2018-06-26T04:00:00Z A supposedly Malaysian curry with shrimp and tofu is stingy with both enhancers; its brick-colored gravy registers mainly as dull heat on the tongue. Mama Rouge in Georgetown leaves this diner feeling bleu 2014-12-12T05:00:00Z “Same with granite. You don’t get the true color until you polish it. But with a leather finish, they don’t polish. So to get the color, they put on a color enhancer — a stain.” Be wary of a ‘leather finish’ on granite 2019-08-09T04:00:00Z Some of these wines are like processed foods, laboratory creations in which the product is fabricated with enzymes, yeasts, tannins and other enhancers until the goal is met. Our Critic Wants You to Try These Supermarket Wines 2018-12-28T05:00:00Z Your slate was probably coated with a sealer or color enhancer, and that’s what’s turning white or gray in response to heat. Restoring the color to slate that’s lost its blackness 2019-09-13T04:00:00Z The trick is to use salt as a flavor enhancer without people noticing that you have used salt. The Single Most Important Ingredient 2017-04-25T04:00:00Z Klayman says the desire for success that drives some people to seek these kind of performance enhancers is “particularly American, and particularly late-stage capitalist”. 'It's a snapshot of America in this moment' - behind the Netflix film on Adderall abuse 2018-03-14T04:00:00Z After cleaning the countertop, apply the color enhancer to just the light areas, Gargiulo said, and then follow that with an application over the entire countertop. Be wary of a ‘leather finish’ on granite 2019-08-09T04:00:00Z The project started in a mouse model of Parkinson's disease where researchers in the laboratory of Julie Andersen, PhD, a senior author of the paper, were looking at known enhancers of mitophagy, including rapamycin. New drug-like molecule extends lifespan, ameliorates pathology in worms and boosts function in mammalian muscle cells 2023-11-13T05:00:00Z Lu envisions the synthetic melanin cream being used as a sunscreen booster for added protection and as an enhancer in moisturizer to promote skin repair. 'Super melanin' heals skin injuries from sunburn, chemical burns 2023-11-02T04:00:00Z Particularly, the accessibility of enhancer regions, a kind of master regulator acting upon many genes at once. Epigenetic changes are paramount in cancer progression 2023-11-06T05:00:00Z This is because DNA contains so-called enhancers, "switches" that ensure that the right genes are turned-on in the right cells at the right time. DNA organization influences the growth of deadly brain tumors in response to neuronal signals 2023-10-31T04:00:00Z This new product, which uses nonspecific ingredients to provide short-term protection against diverse bacteria and fungi, is better called an “immune stimulant” or “enhancer,” they say. Immunity-enhancing cocktail protects mice against multiple hospital germs 2023-10-03T04:00:00Z Composting turns rotting garbage into a valuable soil enhancer that helps plants thrive. How to compost—and why it’s good for the environment 2023-09-26T04:00:00Z Indeed, it often reads like a performance enhancer: “My nerves decohered. I popped two yellow jackets to tamp them down and quash this schizzy limbo.” James Ellroy has his way with 1960s L.A. — and the corpse of Marilyn Monroe 2023-09-08T04:00:00Z “That was the mandate for the team: How do we build something that’s the ultimate productivity enhancer?” OpenAI unveils ChatGPT for businesses, stepping up revenue push 2023-08-28T04:00:00Z This recent study by Umeå researchers highlights that alterations in DNA structure and in enhancers, which in turn affect how genes are expressed, are crucial for the communication between neurons and tumour cells. DNA organization influences the growth of deadly brain tumors in response to neuronal signals 2023-10-31T04:00:00Z Medina Spirit had a positive test for betamethasone, an anti-inflammatory that is not considered a performance enhancer in the traditional sense. Churchill Downs extends trainer Bob Baffert's ban for at least one more year 2023-07-03T04:00:00Z Composting with worms, or vermicomposting, produces an even more valuable soil enhancer. How to compost—and why it’s good for the environment 2023-09-26T04:00:00Z They also argue that because the bill is geared toward stopping widespread doping conspiracies, and not necessarily individual cheaters, athletes won’t be singled out for criminal liability in the U.S. simply for taking performance enhancers. U.S. law passed to stop doping nets its 1st guilty plea 2023-05-08T04:00:00Z “For me it became a performance enhancer,” said Mr. Hess, who founded the Veterans Alliance for Holistic Alternatives, which provides veterans with information about treatments including cannabis and psychedelics. Needing Younger Workers, Federal Officials Relax Rules on Past Drug Use 2023-04-30T04:00:00Z Diners are encouraged to mix the enhancers — unite the elements of mousseline — then do as they please. Review | Yet another French spot in D.C., Petite Cerise charts a personal course 2023-04-21T04:00:00Z Marketing late-night meals as sleep enhancers is a way for the food industry to achieve one of its longtime objectives: To boost sales by creating a so-called fourth meal that follows dinner. Cereal before bed? Food makers push ‘sleep’ snacks at night. 2023-03-14T04:00:00Z "It does things that you can't do in reality. It's a reality enhancer, not an escapism tool." Can VR influencers save the metaverse? 2023-03-10T05:00:00Z It is one of the world’s largest producers of monosodium glutamate, a flavor enhancer. Pentagon: Proposed Chinese plant near N. Dakota base ‘threat to national security’ 2023-02-01T05:00:00Z CLAIM: Flavor enhancers made from aborted fetal tissue are being added to food products without consumers’ knowledge. NOT REAL NEWS: A look at what didn’t happen this week 2023-01-27T05:00:00Z The people behind the famously orange snack food are now suggesting that a sprinkling of ground-up Cheetos can be a flavor enhancer for everything from ice cream to Brussels sprouts to lobster tails. New Cheetos Duster lets you add that unique flavor (and color) to all your food 2022-12-26T05:00:00Z Don’t misunderstand; the sliced duck, aged for three days before it’s smoked with cedar and tea and massaged with five-spice and other enhancers, is a testament to succulence. Review | Worth the wait: Peter Chang finally opens a Chinese restaurant in D.C. 2022-11-11T05:00:00Z Some experts argue that ultra-processed foods hook our brains and overwhelm our biology because they contain unnatural combinations of fat and carbs along with sodium and other flavor enhancers. What are ultra-processed foods? What should I eat instead? 2022-09-27T04:00:00Z Those counts also have a use-of-a-dangerous-weapon penalty enhancer, which would add another five years on each count. Judge lets Wisconsin parade suspect represent himself 2022-09-28T04:00:00Z THE FACTS: Biotechnology companies have frequently used fetal cell lines in their research and testing, but flavor enhancers used in food products do not contain any tissue from aborted fetuses. NOT REAL NEWS: A look at what didn’t happen this week 2023-01-27T05:00:00Z Benzene is one of the compounds used as octane enhancers in unleaded gasoline. Chemistry 2019-02-14T00:00:00Z In addition to promoter sequences, enhancer regions help augment transcription. Biology for AP Courses 2022-06-09T00:00:00Z Some people swear by adding "enhancers" to speed up the breakdown process — alfalfa from your local feed store being a popular choice — but it's not necessary, as your compost is designed to be self-sufficient. How to make compost (because it's not hard) 2022-06-26T04:00:00Z Smoked paprika is one such enhancer, which can also help make up for the quicker cook time. How to grill plant-based meats for the best texture and flavor 2022-05-23T04:00:00Z Totoaba swim bladders, purported to be a fertility enhancer, are prized in China. Genome study offers hope for vaquita, an endangered porpoise in Mexico’s waters 2022-05-13T04:00:00Z He was arrested on suspicion of second-degree criminal tampering with a domestic violence enhancer, a misdemeanor, and had to spend the night in jail until he could appear before a judge because of the enhancer. Jeudy’s girlfriend asks for case against him to be dismissed 2022-05-13T04:00:00Z An army of basal transcription factors, enhancers, and silencers also help to regulate the frequency with which pre-mRNA is synthesized from a gene. Biology for AP Courses 2022-06-09T00:00:00Z Because of the domestic violence enhancer, Jeudy couldn’t be released on bond until appearing before a judge, she said. Broncos WR Jerry Jeudy arrested in domestic-violence case 2022-05-12T04:00:00Z In Anju and Kaechon, north of the capital Pyongyang, people created ponds, added fertiliser and growth enhancer to crops, and sent tractors, trucks and cultivators to carry water to farms, Rodong said. N.Korea mobilises office workers to fight drought amid food shortages 2022-05-04T04:00:00Z It’s generally agreed that the 21 picograms, one-trillionth of a gram, found in Medina Spirit’s system would not be a performance enhancer. Kentucky regulators recorded calls without consent with Baffert after Medina Spirit test 2022-04-03T04:00:00Z Even though authorities did not allege Jeudy committed violence, the sheriff’s office said such enhancers are typically added to cases when there is an intimate relationship between the victim and the suspect. Jeudy’s girlfriend asks for case against him to be dismissed 2022-05-13T04:00:00Z The initiation step in eukaryotes requires an initiation complex with enhancers and transcription factors. Biology for AP Courses 2022-06-09T00:00:00Z The steroid, which MLB does not classify as a performance enhancer, is typically prescribed only for acute pain, according to David Geier, director of sports medicine at the Medical University of South Carolina. Tyler Skaggs’s agent urged him to pitch through pain for years before death, texts show 2022-03-22T04:00:00Z Richards repeatedly acknowledged that his struggles last year were tied to a midseason crackdown by Major League Baseball on the use of illegal grip enhancers by pitchers. Rangers sign veteran RHP Richards to pitch in relief 2022-03-20T04:00:00Z The flavor enhancer MSG is a controversial subject. The year’s big cookbook release is here. A Q&A with Seattle author J. Kenji López-Alt 2022-03-08T05:00:00Z Re-examine the philosophical question of what a recovery agent is in relation to other proven performance enhancers. Perspective | The Kamila Valieva ordeal proved a need for Olympic reform. Here are three places to start. 2022-02-18T05:00:00Z The initiation step in prokaryotes requires an initiation complex with enhancers and transcription factors. Biology for AP Courses 2022-06-09T00:00:00Z History won’t blame her for failing, brand her as a choker or consider her the sole culprit if she’s deemed guilty of taking a performance enhancer. Perspective | Olympic leaders hail the power of the Games. It’s time to use it for some good. 2022-02-18T05:00:00Z The drug is believed to improve endurance by helping the heart work more efficiently, though expert opinions diverge on its potential effectiveness as a performance enhancer. Failed Test Casts Shadow Over Skating, the Olympics’ Showcase Event 2022-02-11T05:00:00Z It is not considered a performance enhancer in the traditional sense but if it relieves discomfort it could allow a horse to run better, much like a human athlete who takes an aspirin or ibuprofen. Cause of Medina Spirit's death remains unknown, no unexpected drugs found 2022-02-11T05:00:00Z And even if the recipient doesn’t bake, present the extract as an instant mood enhancer. Make vanilla extract at home for luxe flavor at a fraction of the cost 2021-11-29T05:00:00Z The elongation step in eukaryotes requires an initiation complex with enhancers and transcription factors. Biology for AP Courses 2022-06-09T00:00:00Z Further crowding the table is a brass plate set off with a bed of rice topped with a fried egg, sprinkled with ground chiles and enhancers of purple onion and lemon wedge. 2021 Fall Dining Guide Psychedelic Water is marketed as a mood enhancer, “like a glass of wine,” that also acts an aphrodisiac for some. Psychedelic Water founder looks to new legal era for powerful drugs 2021-09-19T04:00:00Z Betamethasone is an anti-inflammatory that is not considered a performance enhancer, however is it generally accepted that if a horse is without irritation or pain, it can run better. Churchill Downs goes after suspended trainer Bob Baffert with new policy 2021-09-10T04:00:00Z He studied the vegan meat section in grocery stores and experimented with meat substitutes, wood and flavor enhancers such as brewed coffee and mushrooms. Vegan barbecue is carving out a place in traditional meat-smoking regions 2021-09-02T04:00:00Z Each enhancer is made up of short DNA sequences called distal control elements. Biology for AP Courses 2022-06-09T00:00:00Z Further crowding the table is a brass plate set off with a bed of rice topped with a fried egg, sprinkled with chili powder, and enhancers of purple onion and lemon wedge. Review | Tom Sietsema’s 8 favorite places to eat right now 2021-08-24T04:00:00Z The 35-year-old Donaldson has been among baseball’s most outspoken hitters against the use of illicit grip enhancers by pitchers, which can generate more spin — and therefore more movement. Donaldson gives Giolito his spin on sticky stuff comments 2021-06-30T04:00:00Z Many of us consider that keeping the heat index down is an effective summertime mood enhancer. Sunday was hot, but not unpleasant and not 90 degrees in D.C. 2021-06-27T04:00:00Z The first two were initiated by umpires under Major League Baseball’s new crackdown against sticky substances used as grip enhancers. LEADING OFF: Rays rookie Franco slumping, Harper plunked 2021-06-26T04:00:00Z This shape change allows for the interaction of the activators bound to the enhancers with the transcription factors bound to the promoter region and the RNA polymerase. Biology for AP Courses 2022-06-09T00:00:00Z Cole's explosive fastball was missing and his spin rate dropped as he pitched for the first time since Major League Baseball’s crackdown on grip enhancers began. Cole's strikeouts, spin rate down, Royals rally past Yanks 2021-06-23T04:00:00Z As with all pitchers under MLB’s new policy, Wheeler was checked for grip enhancers. Check, mate: Miffed Max stares down Girardi, Nats top Phils 2021-06-22T04:00:00Z Earlier this week, the Court of Arbitration for Sport upheld Houlihan’s four-year ban for testing positive for trace amounts of the performance enhancer nandrolone. Banned runner allowed to race at US trials pending appeals 2021-06-17T04:00:00Z Glasnow said he’s sure that trying to throw slick baseballs without any grip enhancer helped cause the problem. LEADING OFF: MLB crackdown coming, deGrom up, Glasnow down 2021-06-15T04:00:00Z Transcriptional repressors can bind to promoter or enhancer regions and block transcription. Biology for AP Courses 2022-06-09T00:00:00Z The drug is not considered a performance enhancer. Bob Baffert files suit to spur more testing on Medina Spirit sample 2021-06-08T04:00:00Z There is no scientific evidence that betamethasone is a performance enhancer. What trainer Bob Baffert's suspension means to California racetracks 2021-06-03T04:00:00Z On Monday, Alissa was charged with 13 additional attempted murder counts and dozens of sentence enhancers. Boulder mass shooting suspect slapped with more charges: DA 2021-05-24T04:00:00Z It is not considered a performance enhancer, according to two nationally known equine veterinarians contacted by The Times. All horses, including Kentucky Derby winner Medina Spirit, cleared to run Preakness 2021-05-14T04:00:00Z Alternatively, a mutation in the DNA of a promoter or enhancer region can increase the binding ability of a transcription factor. Biology for AP Courses 2022-06-09T00:00:00Z The Pfizer-BioNTech and Moderna vaccines do not contain live virus or any enhancers to boost an immune response and are not thought to be a risk to the breastfeeding infant. Your questions about coronavirus vaccines, answered Fuller will miss the opener to complete a six-game suspension for using performance enhancers. Dolphins newcomer Will Fuller eager to disprove doubters 2021-03-23T04:00:00Z He now faces 115 criminal charges for his alleged role in the shooting, including 47 crime-of-violence sentence enhancers. Boulder mass shooting suspect slapped with more charges: DA 2021-05-24T04:00:00Z “It’s not something you get arrested for. It’s a sentence enhancer,” said Pete Skandalakis, a former prosecutor and executive director of the Prosecuting Attorneys’ Council of Georgia. Spa shootings could be first test of Georgia hate crimes law 2021-03-19T04:00:00Z The initiation step in eukaryotes requires an initiation complex with enhancers and transcription factors. Biology for AP Courses 2022-06-09T00:00:00Z He missed the first four games of 2019 for using a performance enhancer. Giants cut WR Golden Tate, LB Dave Mayo in salary cap moves 2021-03-04T05:00:00Z One person on Twitter wrote: "Taste of RMB is much better than MSG. Isn't that right Uncle Roger", referring to the Chinese currency and a flavour enhancer commonly added to some Asian foods. Uncle Roger comedian deletes video with China critic 2021-01-13T05:00:00Z The Pfizer-BioNTech and Moderna vaccines do not contain live virus, or any enhancers to boost an immune response, and are not thought to be a risk to the breastfeeding infant. Your questions about coronavirus vaccines, answered The common yet scientifically disproven claim that MSG causes illness made the Chinese food flavor enhancer highly unpopular in the 1970s, forcing many Asian American restaurants to eliminate it from their kitchens. Racism targets Asian food, business during COVID-19 pandemic 2020-12-20T05:00:00Z In addition, other areas on the DNA called enhancer regions help augment transcription. Biology for AP Courses 2022-06-09T00:00:00Z She liked her solitary spin around the city, running on music and mood enhancers. Seeing 2020: A vision of Seattle’s future from 1984 2020-12-13T05:00:00Z Both players set career highs in Houston’s first game since star receiver Will Fuller received a six-game suspension for violating the NFL’s policy on performance enhancers. Rivers, defense help Colts to 26-20 win over Houston Texans 2020-12-06T05:00:00Z He tested positive for performance enhancers and “substances of abuse,” the league said in a statement at the time. NFL reinstates Gordon, can play in final 2 games for Seattle 2020-12-03T05:00:00Z It’s debate night, so I’ve got my earpiece and performance enhancers ready. Biden mocks earpiece, drug testing drama 2020-09-29T04:00:00Z Transcription factors can bind to enhancer regions to increase or prevent transcription. Biology for AP Courses 2022-06-09T00:00:00Z On Tuesday evening, just hours before the debate, the Democratic candidate offered a tongue-in-cheek confirmation that he will be using an "earpiece and performance enhancers." Biden mocks Trump campaign with tweet touting 'earpiece and performance enhancers' ahead of debate 2020-09-29T04:00:00Z It’s debate night, so I’ve got my earpiece and performance enhancers ready. Presidential debate live: Trump and Biden to face off for first time 2020-09-29T04:00:00Z The president on Monday also repeated his demand that Biden take some sort of drug test, asserting without evidence that the Democratic nominee was somehow using a performance enhancer. Trump, Biden prepare to debate at a time of mounting crises 2020-09-28T04:00:00Z That’s not something I ever expected to write about game enhancer software on an Android phone. Sony announces the Xperia 5 II with 120Hz screen and actually useful game enhancements 2020-09-17T04:00:00Z Figure 16.10 An enhancer is a DNA sequence that promotes transcription. Biology for AP Courses 2022-06-09T00:00:00Z Gordon tested positive for performance enhancers and “substances of abuse,” the league said in a statement at the time. Agent: Seahawks bring back suspended WR Josh Gordon 2020-09-03T04:00:00Z Another theory is transport by a misguided performance enhancer. ‘Murder hornets’ threaten apple, cherry harvests 2020-08-30T04:00:00Z As well as being a unisex hairdresser, the business also provides custom-made wigs and hair enhancers. Has pandemic made more want to be their own boss? 2020-08-08T04:00:00Z Most are classified as promoters or enhancers — CREs respectively located at or some distance from the genomic site at which transcription of a gene begins. Expanded ENCODE delivers invaluable genomic encyclopedia 2020-07-28T04:00:00Z Transcription factors bind to enhancer regions to increase or prevent transcription. Biology for AP Courses 2022-06-09T00:00:00Z It neither alleviated nighttime apprehension nor proved effective daytime mood enhancer. Commentary: Bach wrote BWV 82 to transcend tragedy. It's a lullaby for our times too 2020-07-22T04:00:00Z Also, the first ingredient listed on Goya’s original sazón is the flavor enhancer MSG, or monosodium glutamate. You can make sazón at home. All you need are some common kitchen spices. 2020-07-21T04:00:00Z All three busts involve the performance enhancer EPO, cycling’s drug of choice. AP Sportlight 2020-07-16T04:00:00Z They used chromatin-looping data to link enhancers to genes that they might regulate. Expanded ENCODE delivers invaluable genomic encyclopedia 2020-07-28T04:00:00Z Menno Creyghton of the Erasmus University Medical Center in the Netherlands and his colleagues found that certain enhancers in humans and chimps differed significantly from those in more distantly related macaques and marmosets. How Human Brains Are Different: It Has a Lot to Do with the Connections 2020-07-07T04:00:00Z In Navarro’s barn, horses were subjected to something called “a drench,” a cocktail of enhancers shot into their stomach via a tube forced down the larynx and esophagus. Perspective | If horsemen care so much about animals, why does it take the feds to stop doping? 2020-03-09T04:00:00Z Or it may contain additives such as “flavour enhancers, colours, emulsifiers, emulsifying salts, sweeteners, thickeners and anti-foaming, bulking, carbonating, foaming, gelling and glazing agents”. How ultra-processed food took over your shopping basket 2020-02-12T05:00:00Z One approach delivers engineered viruses into the brain to test thousands of enhancers for the gene-expression profile of interest. Technologies to watch in 2020 2020-01-20T05:00:00Z Intriguingly, both groups demonstrated that the human equivalents of some mouse enhancer elements — those that are active only in specific tissues — are enriched for genetic variants associated with diseases relevant to the corresponding tissue. Expanded ENCODE delivers invaluable genomic encyclopedia 2020-07-28T04:00:00Z Meanwhile, Josh Gordon’s career hangs in the balance after the Seahawks wide receiver was suspended indefinitely for violating league policies on performance enhancers and substance abuse. US briefing: impeachment fight, North Korea and capital punishment 2019-12-17T05:00:00Z In many countries, it is thought to be a mood enhancer or treatment for depression and post-traumatic stress. `'Safer opioid’ has sparked a crisis in vulnerable countries 2019-12-13T05:00:00Z In any case, these problems are only hypothetical, and current use of potent enhancers is limited to relatively small sections of society. The Runaway Train of Cognitive Enhancement 2019-12-09T05:00:00Z In 2019, researchers at the Allen Institute for Brain Science in Seattle, Washington, used this strategy to look for enhancers in specific cortical layers in the human brain9. Technologies to watch in 2020 2020-01-20T05:00:00Z The researchers are also testing the use of another vaccine as an enhancer, or adjuvant, for the hepatitis B vaccine. Tailoring vaccines for older people and the very young 2019-11-26T05:00:00Z Many of the waitstaff seemed to be on chemical mood enhancers. My Life as a Child Chef 2019-11-18T05:00:00Z He was one of several horses that tested positive for the drug, which is not a performance enhancer. After a year marred by horse deaths, CHRB head Rick Baedeker says he's retiring 2019-11-10T05:00:00Z If a response comes only once the next generation of enhancers is readily available, it will be too little too late. The Runaway Train of Cognitive Enhancement 2019-12-09T05:00:00Z Prosecutors added hate crime and use of a dangerous weapon as sentencing enhancers that could increase his punishment if convicted. The Latest: Acid attack victim glad for hate crime charge 2019-11-06T05:00:00Z Climate change acts as a performance enhancer, and understandably, it claims most of the attention because it’s global and its reach extends beyond flames to oceans, mass extinctions and other knock-on effects. California wildfires signal the arrival of a planetary fire age 2019-11-03T04:00:00Z Tate’s four-game suspension for using performance enhancers and injuries to Shepard and Barkley prevented that in the opening eight games. Giants WR Sterling Shepard coming back after 2nd concussion 2019-11-02T04:00:00Z "Climate change acts as a performance enhancer, and understandably, it claims most of the attention because it's global and its reach extends beyond flames to oceans, mass extinctions and other knock-on effects," he explains. California wildfires signal a ‘fire age,’ expert claims 2019-11-01T04:00:00Z Increasingly prevalent and effective enhancers carry the likelihood of deepening inequality, since the wealthier in society will have early access to the most advanced drugs and neurotechnology, gaining even more of an advantage. The Runaway Train of Cognitive Enhancement 2019-12-09T05:00:00Z Prosecutors added the sentencing enhancers of hate crime and use of a dangerous weapon. The Latest: Acid attack victim glad for hate crime charge 2019-11-06T05:00:00Z It’s easy to overlook these flavor enhancers as just that — flavor — but herbs are plants, and spices are concentrated plants. How and why to boost your intake of antioxidants 2019-10-29T04:00:00Z Salazar was also accused of misusing and trafficking in testosterone, which has long been recognized as one of the most basic and easy-to-detect performance enhancers. Suspicious athletes led to coaching great Salazar’s downfall 2019-10-01T04:00:00Z Salazar was also accused of misusing and trafficking in testosterone, which has long been recognized as one of the most basic and easy-to-detect performance enhancers. Suspicious athletes led to coaching great Salazar’s downfall 2019-10-01T04:00:00Z Jones needs to incorporate Tate as he returns from a four-game suspension for using performance enhancers. After winning 2 in row, Giants face real test with Vikings 2019-09-30T04:00:00Z Most veterinarians believe the banned drug, scopolamine, found in the feed is not a performance enhancer. Santa Anita opens fall season Friday under scrutiny 2019-09-26T04:00:00Z While collagen is probably most well known for its touted skin care benefits and as a major component of lip enhancers and injections, some celebrities, like Kourtney Kardashian, are suggesting that people drink it. Collagen in your coffee? A scientist says forget it 2019-09-22T04:00:00Z Veteran Golden Tate III is suspended for the first four games for violating the policy on performance enhancers. Elliott, Manning take center stage in Cowboys-Giants opener 2019-09-05T04:00:00Z The owner wasn’t shy about revealing some other performance enhancers he gives his steeds. For Indonesia’s Child Jockeys, Time to Retire at 10, After 5 Years of Racing 2019-08-24T04:00:00Z The hardest decision for Shurmur and his staff may be at wide receiver, even with Golden Tate III out for the first four games for a violation of the rules on using performance enhancers. Shurmur has tough choices to make with cuts next week 2019-08-23T04:00:00Z New England signed Ben Watson out of retirement in the offseason, but he’s suspended the first four games for violating the NFL’s policy on performance enhancers. NFL 2019: AFC East: It’s Old Man Brady and the Young Gun QBs 2019-08-22T04:00:00Z Arizona already knew that cornerback Patrick Peterson would miss the season’s first six games for violating the NFL’s policy on performance enhancers. NFL 2019: Kingsbury, Murray lead Cardinals into new era 2019-08-22T04:00:00Z He will be serving a four-game suspension for violating the policy on performance enhancers. NFL 2019: Eyes on Jones in what could be Eli’s final year 2019-08-22T04:00:00Z Add accessory enhancers such as artwork, fun bedding, area rugs and toss pillows. How to incorporate kid-friendly colors into your home | Produced by Advertising Publications 2019-07-12T04:00:00Z In the late 19th and early 20th centuries it was used in small doses as an athletic performance enhancer and recreational stimulant. Kenyan banned after positive test for rat poison substance 2019-06-12T04:00:00Z Ultra-processed foods tend to be formulated from industrial ingredients, blending starches, sugar and saturated fats with additives such as preservatives, binders, bulkers, sweeteners, flavourings and “sensory enhancers”. Studies link too much heavily processed food to early death 2019-05-29T04:00:00Z Nearly all the food at grocery stores is subject to some processing: It’s pasteurized, vacuum sealed, cooked, frozen, fortified, and mixed with preservatives and flavor enhancers. ‘Ultraprocessed’ foods may make you eat more, clinical trial suggests 2019-05-16T04:00:00Z He was waived after serving a two-game suspension to start last season for violating the league’s policy on performance enhancers. Former Alabama, Jets receiver Ardarius Stewart arrested 2019-04-11T04:00:00Z The tACS tuning prompted greater improvements in older people than in younger ones, the study found, which suggests that the tool is more a corrective than an enhancer of memory. To Improve Memory, Tune It Like an Orchestra 2019-04-08T04:00:00Z Her family's mixes don't contain preservatives or flavour enhancers and are made using traditional grinding methods, with matriarch Bhagvanti overseeing the process and giving the final sign-off. Would you put cumin on a pizza? 2019-03-14T04:00:00Z He ran into injury trouble in each of the last two seasons and also missed four weeks for violating the league’s policy on performance enhancers. Steelers sign CB Steven Nelson, bring back Chickillo, Berry 2019-03-13T04:00:00Z Consider his line of grooming products, which includes deodorant, liniment balm and tattoo enhancer cream. The Truth According to Zlatan 2019-03-01T05:00:00Z The first suspension for Irving at the start of 2017 was for violating the league’s policy on performance enhancers. David Irving suspended indefinitely for 3rd ban in 3 years 2019-03-01T05:00:00Z But most permeation enhancers allow less than 1% of peptides to cross into the bloodstream. Pills armed with tiny needles could inject insulin, other important meds directly into the stomach 2019-02-07T05:00:00Z He missed the entire 2017 season with a torn ACL and the first four games of this season for violating the league’s performance enhancers policy. ‘Bromance’ of Brady and Edelman key to Patriots success 2019-01-29T05:00:00Z Then came news that stalwart receiver Julian Edelman would be suspended for the first four games of the regular season for violating the league’s policy on performance enhancers. Hurdles cleared, Patriots head to 3rd straight Super Bowl 2019-01-21T05:00:00Z “If you ever failed a test, got suspended, or admitted to using performance enhancers you should NOT be in the hall of fame,” he wrote. Baseball players linked to PEDs 'disgraced the integrity of the game,' don't belong in Hall of Fame, MLB star says 2019-01-18T05:00:00Z But the role of these clusters was unclear because deletion of potential trans enhancers affected only the expression of olfactory genes on the same chromosome10. Chromosomes come together to help mice distinguish odours 2019-01-08T05:00:00Z The waste will be sent elsewhere to be made into a "compost-like soil enhancer", according to the council. How to get rid of your Christmas tree 2019-01-03T05:00:00Z The flavor enhancers and preservatives BHA and BHT are subject to severe restrictions in Europe but are widely used in American food products. What Foods Are Banned in Europe but Not Banned in the U.S.? 2018-12-28T05:00:00Z For exposure by inhalation, powdered drugs would have to be aerosolized; for absorption through the skin, they would have to be dissolved in liquid or formulated with a “permeation enhancer,” according to a scholarly article. What Can Make a 911 Call a Felony? Fentanyl at the Scene 2018-12-17T05:00:00Z But it is still unclear whether these DNA segments are truly stronger versions of better-known gene-regulating sequences called enhancers. Cancer researchers seek to harness mysterious DNA ‘super-enhancers’ 2018-12-04T05:00:00Z The expression of vertebrate genes is regulated by activating genomic elements called enhancers. Chromosomes come together to help mice distinguish odours 2019-01-08T05:00:00Z She is a more persuasive sleep saleswoman precisely because she does not champion slumber solely as a mental-health aid—an enhancer of acuity and efficiency, and so forth—but as an end in itself. Why We Sleep, and Why We Often Can’t 2018-12-03T05:00:00Z Liuget missed the first four games for violating the league’s policy on performance enhancers but bolstered the pass rush in the six games he played. Chargers look to regroup after loss to Broncos 2018-11-19T05:00:00Z He demonstrated familiarity with, if not authority about, fermented black beans, Chinese five spice, Chinese barbecue pork and even monosodium glutamate, or MSG, which he wholeheartedly embraced as a flavor enhancer. Review | With tiki drinks and Chinese food, this U Street bar channels Trader Vic’s for millennials 2018-11-05T05:00:00Z But in 2013, researchers found2 that some enhancers, called super-enhancers, cluster together near genes that help to determine a cell’s unique identity — whether it becomes a mammary or a muscle cell, for instance. Cancer researchers seek to harness mysterious DNA ‘super-enhancers’ 2018-12-04T05:00:00Z To think of meditation as some type of performance enhancer in deep-breathing form is to misinterpret the underlying machinations at work. Can meditation make you a better golfer? Yes . . . eventually - Golf Digest 2018-10-30T04:00:00Z I find it to be a mild enhancer of daily subjective experience, not an agitator provoking bar fights and public outbursts. Opinion | I'm Just a Middle-Aged House Dad Addicted to Pot 2018-10-06T04:00:00Z Cornerback Jimmy Smith returned to the team Monday and will practice this week after serving a four-game suspension from the NFL for using performance enhancers. Harbaugh views Ravens victory over Steelers as “a big deal” 2018-10-01T04:00:00Z The good news for Brady is that receiver Julian Edelman is now eligible to play after being suspended for the first four games of the season for violating the NFL’s policy on performance enhancers. Patriots again look like pride of division in win over Miami 2018-10-01T04:00:00Z But the results are inconclusive: some enhancers show signs of working together, whereas others seem to work independently. Cancer researchers seek to harness mysterious DNA ‘super-enhancers’ 2018-12-04T05:00:00Z Stewart was suspended two games by the NFL after violating the league’s policy on performance enhancers. Jets waive 2017 third-rounder WR ArDarius Stewart 2018-09-19T04:00:00Z Baltimore also waived tight end Darren Waller, who recently returned from a year-long suspension for violating the league’s policy on performance enhancers. Robert Griffin III survives Ravens’ final cut 2018-09-01T04:00:00Z The main region of sequence amplification associated with AR was in the same enhancer region that was identified by Takeda and colleagues. Sequence of events in prostate cancer 2018-08-23T04:00:00Z The burgers can ride that fine line between salt as flavor enhancer and salt as sodium pirate — the latter can hijack an entire dish. Review | A steakhouse chain makes the cut with its tasty new burger joint 2018-08-20T04:00:00Z Mark Ingram, suspended the first four games of the regular season for violating NFL policy on performance enhancers, carried seven times for 23 yards and a touchdown. Jaguars’ Bortles solid in exhibition opener against Saints 2018-08-09T04:00:00Z Mark Ingram, suspended the first four games of the regular season for violating NFL policy on performance enhancers, carried seven times for 23 yards and a touchdown. Mayfield and Barkley have strong debuts in preseason opener 2018-08-09T04:00:00Z According to the OECD, just 16 percent of German firms use cloud services, “a key productivity enhancer.” Special Report: Rebooting Germany - Where Europe's most powerful... 2018-06-25T04:00:00Z Viswanathan and colleagues found that the enhancer amplification was present in 87% of their samples, either with or without an amplified copy of AR. Sequence of events in prostate cancer 2018-08-23T04:00:00Z Across the genome about 1 million enhancers control nearly 21,000 genes. The little piece of DNA that makes girls boys 2018-06-14T04:00:00Z "It's only recently I've thought about using these enhancers to get me to where I want to be by summer." Steroids a 'ticking time bomb' for NHS 2018-06-13T04:00:00Z The fall from grace of Dr. Jackson has served as a mood enhancer for Dr. Bornstein, who coveted the White House job. Former Trump doctors create thorny political issues for president 2018-05-01T04:00:00Z Great piece, but I wish there had been mention of worm compost as a valuable soil enhancer. Can Dirt Save the Earth? 2018-04-18T04:00:00Z The high prevalence of this type of amplification is notable because enhancer amplifications identified so far for other cancer types generally arise at much lower frequency13–16. Sequence of events in prostate cancer 2018-08-23T04:00:00Z If allowed sports betting, will be a revenue enhancer for education in New York. Editorials from around New York 2018-04-18T04:00:00Z Irving was suspended the first four games last season for violating the NFL’s ban on performance enhancers and missed the last four with a concussion. Pass rusher David Irving returns to Cowboys on $2.9M deal 2018-04-16T04:00:00Z Environment drives selection and function of enhancers controlling tissue-specific macrophage identities. Innate immune memory in the brain shapes neurological disease hallmarks 2018-04-10T04:00:00Z This indicates that long-lasting enhancer activation in microglia requires both brain pathology and an inflammatory insult. Immune memory in the brain 2018-04-10T04:00:00Z One end of the counter was piled with “mood enhancers” - vegetables and whole grains - while the other sported a sign listing “mood depressors” such as candy, soda and fried food. Cooking classes aim to restore health after addiction 2018-04-01T04:00:00Z Firearms charges are usually penalty enhancers, adding years to someone’s sentence if they carry a weapon while dealing drugs or engaging in another crime. Firearm offense convictions declined under Obama, says new report 2018-03-15T04:00:00Z Here we show that the pervasive presence of multiple enhancers with similar activities near the same gene confers phenotypic robustness to loss-of-function mutations in individual enhancers. Enhancer redundancy provides phenotypic robustness in mammalian development 2018-01-30T05:00:00Z Latent enhancers activated by stimulation in differentiated cells. Innate immune memory in the brain shapes neurological disease hallmarks 2018-04-10T04:00:00Z The researchers demonstrated that microglial tolerance led to enhancer and gene-expression changes associated with a process called phagocytosis, by which microglia ingest material to be broken down. Immune memory in the brain 2018-04-10T04:00:00Z "By law, it has to be made with 100% agave, which eliminates the possibility of additives or flavor enhancers." You'll avoid a New Year's hangover with these spirits – LA Times 2017-12-23T05:00:00Z Kerley, who was able to practice last week, reiterated that he didn’t knowingly ingest a performance enhancer but jokingly said perhaps “a ghost put it in me.” With suspension over, WR Jeremy Kerley cut by Jets 2017-12-18T05:00:00Z We used genome editing to create 23 mouse deletion lines and inter-crosses, including both single and combinatorial enhancer deletions at seven distinct loci required for limb development. Enhancer redundancy provides phenotypic robustness in mammalian development 2018-01-30T05:00:00Z Remodeling of the enhancer landscape during macrophage activation is coupled to enhancer transcription. Innate immune memory in the brain shapes neurological disease hallmarks 2018-04-10T04:00:00Z By contrast, training led to enhancer and gene-expression changes associated with inflammation and energy expenditure. Immune memory in the brain 2018-04-10T04:00:00Z Reorganization of enhancer patterns in transition from naive to primed pluripotency. Pluripotent state transitions coordinate morphogenesis in mouse and human embryos 2017-11-28T05:00:00Z Houston lost linebacker Brian Cushing for 10 games because of a suspension for performance enhancers. Houston’s Savage returned to game after concussion 2017-12-10T05:00:00Z Unexpectedly, none of the ten deletions of individual enhancers caused noticeable changes in limb morphology. Enhancer redundancy provides phenotypic robustness in mammalian development 2018-01-30T05:00:00Z Baltimore will be without veteran cornerback Jimmy Smith , who is serving a four-game suspension for violating the league’s policy on performance enhancers. Steelers can clinch AFC North title against surging Ravens 2017-12-07T05:00:00Z Could targeting enhancer activity be a way of regulating immune memory in the brain, thereby altering the progress of neurological disorders? Immune memory in the brain 2018-04-10T04:00:00Z Titgemeier also recommends using vinegars and citrus for marinades and cooking: “They are acidic, which works as a natural flavor enhancer.” Too much sodium is unhealthy, and some favorite foods are a problem 2017-11-03T04:00:00Z An atlas of active enhancers across human cell types and tissues. Association analysis identifies 65 new breast cancer risk loci 2017-10-22T04:00:00Z In a genetic background sensitized by reduced baseline expression of the target gene, even single enhancer deletions caused limb abnormalities, suggesting that functional redundancy is conferred by additive effects of enhancers on gene expression levels. Enhancer redundancy provides phenotypic robustness in mammalian development 2018-01-30T05:00:00Z Marshall served a four-game suspension to start the season for violating the NFL’s policy on performance enhancers to start the season. Jets sign WR Jalin Marshall to practice squad 2017-10-16T04:00:00Z For instance, metabolic products are often required for the activity of enzymes that regulate enhancers. Immune memory in the brain 2018-04-10T04:00:00Z He served a four-game suspension for violating the NFL’s policy on performance enhancers to start the season and was reinstated to the active roster last Monday. Jets waive WR Jalin Marshall, promote CB Xavier Coleman 2017-10-14T04:00:00Z Combinatorial effects of multiple enhancer variants in linkage disequilibrium dictate levels of gene expression to confer susceptibility to common traits. Association analysis identifies 65 new breast cancer risk loci 2017-10-22T04:00:00Z Together, our data indicate that enhancer redundancy is a remarkably widespread feature of mammalian genomes that provides an effective regulatory buffer to prevent deleterious phenotypic consequences upon the loss of individual enhancers. Enhancer redundancy provides phenotypic robustness in mammalian development 2018-01-30T05:00:00Z Marshall was suspended the first four games of the regular season for violating the NFL’s policy on performance enhancers. Jets activate WR Marshall, waive CB Williams 2017-10-09T04:00:00Z Perhaps changes in metabolism mediate and perpetuate enhancer activation in microglia. Immune memory in the brain 2018-04-10T04:00:00Z The move Tuesday potentially clears a spot on the active roster for wide receiver Jalin Marshall, who was suspended the first four games for violating the NFL’s policy on performance enhancers. Jets waive TE Tye, release RB Murphy from practice squad 2017-10-03T04:00:00Z The two-time Pro Bowl running back was activated Monday after completing a four-game suspension for violating the NFL’s policy on performance enhancers and expects to play against the New England Patriots on Thursday night. Bucs’ Martin back from suspension, expects to face Patriots 2017-10-02T04:00:00Z A high-resolution enhancer atlas of the developing telencephalon. Enhancer redundancy provides phenotypic robustness in mammalian development 2018-01-30T05:00:00Z For Pang, this shows how “modern capitalism is capable of turning anything either into a product you consume or an enhancer of productivity”. Do yoga, work harder: how productivity co-opted relaxation 2017-09-20T04:00:00Z Whether this is the case, and how specific enhancers are then targeted for training or tolerance, remains unknown. Immune memory in the brain 2018-04-10T04:00:00Z To write this article, I drank a beverage containing an effective cognitive enhancer - something that helps me - almost daily - to focus. Science debate: Should we embrace an enhanced future? - BBC News 2017-09-08T04:00:00Z Johnson was suspended 10 games last season for violating the NFL’s policy on performance enhancers. Redskins’ Brown responds to trash talk from Eagles’ Johnson 2017-08-25T04:00:00Z Partially redundant enhancers cooperatively maintain mammalian pomc expression above a critical functional threshold. Enhancer redundancy provides phenotypic robustness in mammalian development 2018-01-30T05:00:00Z Jalin Marshall was the Jets’ main returner last season as a rookie, but is suspended the first four games for violating the league’s policy on performance enhancers. Jets’ Whitehead having foot surgery, return duties uncertain 2017-08-16T04:00:00Z Collins would not share specifics of the performance enhancer or say if it was the same one that led to the 2016 suspension. Collins’ future with Falcons uncertain following suspension 2017-08-07T04:00:00Z The player honorees on Sunday made their statistical bones in the so-called steroid era, and two of them were not immune from suspicions of using performance enhancers. At Cooperstown, a Good Day for Bud Selig, but Not a Perfect One 2017-07-30T04:00:00Z Likewise, PRDM6—a presumed histone methyltransferase38 not previously implicated in MB—was identified as the probable target of SNCAIP-associated enhancer hijacking in Group 4, now representing the most prevalent driver alteration in this subgroup. The whole-genome landscape of medulloblastoma subtypes : Nature : Nature Research 2017-07-18T04:00:00Z Shadow enhancers are pervasive features of developmental regulatory networks. Enhancer redundancy provides phenotypic robustness in mammalian development 2018-01-30T05:00:00Z I had a little bit of reflux, heartburn, but in general it was a cognitive enhancer. Tweaking brains with ‘smart drugs’ to get ahead in Silicon Valley 2017-06-09T04:00:00Z This “revenue enhancer” punishes seniors and those with chronic medical problems who see doctors frequently. Rant & Rave: Expert guides to low-tide sea life 2017-06-02T04:00:00Z By contrast, he said the “My Brilliant Friend” production represented a “huge opportunity for the city,” as both a financial investment and an image enhancer. A Casting Call in Naples Lets Children Dream, if for a Day 2017-05-18T04:00:00Z He had 421 yards and three touchdowns a year ago, when he missed eight games because of injuries and a suspension that will extend into next season for violating the NFL's policy on performance enhancers. NFL report: Buccaneers RB Doug Martin sustains minor injuries in car accident 2017-05-04T04:00:00Z Progressive loss of function in a limb enhancer during snake evolution. Enhancer redundancy provides phenotypic robustness in mammalian development 2018-01-30T05:00:00Z He was plagued by a series of injuries and also served a four-game suspension for violating the NFL policy on performance enhancers. Colts release veteran DT Arthur Jones 2017-03-24T04:00:00Z Yet ephedra extracts that weren’t included in the agency’s ban are still available online as a performance enhancer for athletes. Bitter pill to swallow: Less FDA oversight of supplements seems likely 2017-03-21T04:00:00Z As Jones says, God’s help on the field of play would indeed be the ultimate “performance enhancer”. Divine intervention: will God decide Super Bowl 51? 2017-02-03T05:00:00Z Resisting these life enhancers takes steely resolve, which not everybody possesses. Not Seen on TV: Hefty Handling Charges 2017-01-13T05:00:00Z Selig was baseball’s commissioner for nearly a quarter of a century, including the period in which the use of steroids and other performance enhancers flourished. Hall of Fame Odds Slip for Barry Bonds and Roger Clemens 2017-01-09T05:00:00Z As a result, enhancers from neighboring estates suddenly had access to genes they were not meant to activate. A Family’s Shared Defect Sheds Light on the Human Genome 2017-01-09T05:00:00Z The grills are used as display enhancers in retail, liquor, convenience and other stores or were received by consumers as promotional giveaways and at charity auctions. Recalls this week: strollers, crossbows 2016-12-23T05:00:00Z “While half of Americans believe God may function as a kind of performance enhancer for religious athletes, only one-quarter believe God actually throws the game to one side or the other.” Divine intervention: will God decide Super Bowl 51? 2017-02-03T05:00:00Z There is very little solid clinical evidence on “performance enhancers” at all. WADA report misses mark by focusing on the wrong targets 2016-12-09T05:00:00Z Natural herbs and spices are another category of satiety enhancers. How to Build a Healthy Meal That Actually Keeps You Full 2016-12-05T05:00:00Z The new research indicates that switches and enhancers act only on those genes, those protein codes, stationed within their own precincts. A Family’s Shared Defect Sheds Light on the Human Genome 2017-01-09T05:00:00Z Meanwhile washers and dryers offer increasingly specialized settings, and detergents and fabric enhancers are getting more specific, adding to the necessity of reading and understanding the labels. Does Anyone Understand Those Laundry-Tag Symbols? 2016-11-01T04:00:00Z An enhancer controls the activation of the Sonic hedgehog gene, causing it to flicker on and off. Snakes Evolved Out of Their Legs—but They Still Have the Gene And look, I’ve got to tell you, I am so flattered that Donald thought I used some sort of performance enhancer. Read Hillary Clinton's Al Smith Dinner Speech 2016-10-21T04:00:00Z “I am so flattered that Donald thought I use some sort of performance enhancer,” she said. Trump booed for calling Clinton 'corrupt' as bipartisan dinner turns sour 2016-10-20T04:00:00Z But under normal circumstances, one thing an Upper West Side enhancer will not do is reach across town to twiddle genes residing on the Upper East Side. A Family’s Shared Defect Sheds Light on the Human Genome 2017-01-09T05:00:00Z Even with the fish and human enhancers, the mouse legs developed normally, demonstrating that enhancers from other species still work in the mice. Tiny DNA tweaks made snakes legless 2016-10-20T04:00:00Z In snakes, a mutation in the enhancer keeps the gene from staying in the “on” position, allowing for limbs to grow. Snakes Evolved Out of Their Legs—but They Still Have the Gene The drug at the center of the controversy, triamcinolone acetonide, when used without permission is an old-fashioned sort of performance enhancer. Team Sky Tried to Rise Above Doping and Landed in an Ethics Quagmire 2016-10-14T04:00:00Z There are transmission paddle shifters, an engine noise enhancer and heated and air-conditioned sport seats with leather upholstery. Lexus redesigns 2016 SUV 2016-10-16T04:00:00Z In this instance, disruption of the nearby binding site, Dr. Young said, “broke up the neighborhood and allowed an outside enhancer to push TAL1 to the point of tumorigenesis,” the production of tumors. A Family’s Shared Defect Sheds Light on the Human Genome 2017-01-09T05:00:00Z Situated in front of the gene, this switch, called an enhancer, is a docking site for proteins that control the gene’s activity. Tiny DNA tweaks made snakes legless 2016-10-20T04:00:00Z The CAS ruling on Tuesday rejected that finding and concluded that Sharapova had taken the drug, on the advice of her physician, for medical reasons, not as a performance enhancer. Maria Sharapova’s Doping Suspension Reduced to 15 Months 2016-10-04T04:00:00Z But what I don’t understand is that you’ve automatically just assumed that this was a performance enhancer. Wiggins: ‘I was paranoid about making excuses. It wasn’t something I was going to shout from the rooftops’ 2016-09-30T04:00:00Z “This intervention is not a self-esteem enhancer, which is a failed model,” Dr. Steinberg said. Teaching Teenagers to Cope With Social Stress 2016-09-29T04:00:00Z Bernie’s job is to serve as an enhancer to the traditional therapies by performing specific tasks that get me through the day, and sometimes the night. 9/11 First Responder: How My Service Dog Helps Me Heal 2016-09-09T04:00:00Z They then showed that a mutated Sonic hedgehog enhancer does indeed affect leg growth by testing its influence on mouse limbs. Tiny DNA tweaks made snakes legless 2016-10-20T04:00:00Z Record enhancer postbaccalaureate programs offer applicants the opportunity to redeem themselves by taking upper-division life science courses over the span of a year. 6 Types of Applicants Who Would Benefit from a Postbaccalaureate Program 2016-09-01T04:00:00Z Johnson reportedly is in line for a 10-game suspension for violating the league’s performance enhancers policy. Eagles coach preparing for possible Lane Johnson suspension 2016-08-11T04:00:00Z It’s possible that legalizing performance enhancers may be the most honest and efficient thing we could do to level the playing field for all and promote better health among athletes. Want to end the Olympic war on performance-enhancing drugs? Legalize them 2016-08-04T04:00:00Z “Brewers are allowed to artificially color, flavor, sweeten, and preserve their products, as well as use foam enhancers,” he said in a statement. Beers may offer nutrition info alongside ingredient details 2016-07-12T04:00:00Z They also repeated the experiment, subbing in the same enhancer from a fish and, later, from a human. Tiny DNA tweaks made snakes legless 2016-10-20T04:00:00Z His beloved status is somewhat remarkable, given that in 2012, while playing for the Oakland Athletics, Colon was suspended 50 games for using performance enhancers. Crafty Bartolo Colon Defeats Jake Arrieta, Cubs’ Ace 2016-07-02T04:00:00Z According to Nicholas Christenfeld, a professor of psychology at UC San Diego who has researched the role of spoilers relative to literature, the leaked tidbits could just as easily be called enhancers. 'The Bachelorette' and its spoilers 2016-05-23T04:00:00Z These enhancers were located close to genes involved in limb development, so he and his colleagues expected the embryo's limbs to be defective in some way. Biologists identify the backup systems that ensure genes build limbs 2016-05-20T04:00:00Z Fufeng Group, the world's largest producer of food flavor enhancer MSG, didn't return a Reuters request for comment after regular business hours. JPMorgan becomes first global bank to fall foul of Hong Kong's stricter IPO sponsorship rules 2016-05-05T04:00:00Z But with the snake enhancer, the legs turned into little nubs, Visel and his colleagues report today in Cell. Tiny DNA tweaks made snakes legless 2016-10-20T04:00:00Z “I was making a speech about sleep as a performance enhancer,” she said. Arianna Huffington’s Sleep Revolution Starts at Home 2016-04-28T04:00:00Z Complicated makes a line-up of flavor enhancers that you can use to spruce up your cocktail... or soda, if you're boring. The weird future of movie theater food 2016-04-15T04:00:00Z The enhancers “are redundant on an organismal level, but additive at a molecular level,” Osterwalder concluded. Biologists identify the backup systems that ensure genes build limbs 2016-05-20T04:00:00Z The two chefs plan on developing their own all-natural version of the notorious flavor enhancer. Encino is about to get a new ramen restaurant from two big-name chefs 2016-03-30T04:00:00Z Recently, for example, other researchers discovered that another enhancer was responsible for snakes’ extra ribs and long backbones. Tiny DNA tweaks made snakes legless 2016-10-20T04:00:00Z “It’s another revenue enhancer for the State of New York,” Mr. Bonacic said on Monday. New York State Considers Further Expansion of Once-Illicit Activities 2016-03-22T04:00:00Z Incorporate mushrooms. These are an important flavor enhancer because they provide a rich and savory taste associated with foods like meat, but without the fat, calories and sodium. Savor the Flavor of Eating Right While Managing Diabetes 2016-03-22T04:00:00Z Three years ago, another team studying enhancers in the development of the mouse face and skull uncovered similar complexity. Biologists identify the backup systems that ensure genes build limbs 2016-05-20T04:00:00Z Ivars, of Latvia’s Institute of Organic Synthesis, called meldonium “the safest cardiovascular drug in the world” and added: “Nobody has demonstrated that it is an enhancer or performance booster. The only evidence is anecdotal.” Banned Substance Defended 2016-03-18T04:00:00Z And it’s possible that the Sonic hedgehog enhancer was not the first step in leg loss, Hanken says. Tiny DNA tweaks made snakes legless 2016-10-20T04:00:00Z Food and Drug Administration in 2013 released voluntary guidelines for drug makers and agricultural companies to phase out antibiotic use as a growth enhancer in livestock. Cargill says to cut antibiotic use in cattle by 20 percent 2016-03-08T05:00:00Z Other sequences are 'enhancers' that amplify the expression of the genes under their command. CRISPR: gene editing is just the beginning 2016-03-06T05:00:00Z And studies in Drosophila suggest, too, that interactions of multiple enhancers are commonplace. Biologists identify the backup systems that ensure genes build limbs 2016-05-20T04:00:00Z “What better value enhancer for dividend yielders than the threat of the fixed-income market going to negative yields?” said James Paulsen, chief investment officer at Wells Capital Management, which oversees $348 billion. High-Dividend Stocks Gain Appeal 2016-02-28T05:00:00Z Finally, when researchers put the missing DNA into the snake enhancer and then put the modified enhancer back into mice, their legs grew just fine. Tiny DNA tweaks made snakes legless 2016-10-20T04:00:00Z “There was much grief and suffering because so many of her family members were being killed in battle, so she used a homemade mood enhancer from rose petals, a fore-runner of modern day antidepressants.” Jacksonport woman uses Civil War era medicinal practices 2016-02-15T05:00:00Z Most of the DNA sequences linked to the risk of common diseases lie in regions of the genome that contain non-coding RNA and enhancers. CRISPR: gene editing is just the beginning 2016-03-06T05:00:00Z Noncoding DNA includes stretches called enhancers, short sequences that help control a target gene. Biologists identify the backup systems that ensure genes build limbs 2016-05-20T04:00:00Z But when engaging in the same behavior ourselves, we see the enhancer as simply enabling latent ability that we already had. All You Need to Know About the Election You Learned From Sports 2016-02-05T05:00:00Z They were then known as bodybuilding enhancers and were not known to the public. Letters to the Editor 2016-01-23T05:00:00Z But Mitchell doesn’t avoid alcohol entirely—in fact, he regards it as a performance enhancer. The Making of a Champion Darts Player 2016-01-09T05:00:00Z In one unpublished experiment, her team deleted an enhancer that was thought to be important, yet no gene within one million bases of it changed expression. CRISPR: gene editing is just the beginning 2016-03-06T05:00:00Z The result was a functional map of genetic 'enhancer' sequences that allows researchers to determine what these enhancers do, how strongly, and — most importantly — where they are located in the genome. Epigenetics: The genome unwrapped : Nature : Nature Publishing Group 2015-12-01T05:00:00Z But it’s not often thought of as a performance enhancer in the bedroom. Does alcohol really make you better in bed? 2015-11-17T05:00:00Z By changing the proportion of yeast extract and other flavorings, Mr. Fellows said, he was able to offset the loss of the chemical flavor enhancers. Campbell Rethinks Its Recipe as Consumer Tastes Change 2015-11-09T05:00:00Z Indeed, this Indian flavor enhancer was a lot more popular in 19th-century America than most people might imagine. Some Surprising Relics at the Tenement Museum 2015-11-06T05:00:00Z Should their use as cognitive enhancers be approved by the FDA, the medical community and society at large? ‘Smart pills’ for college students: Would that be cheating? 2015-10-26T04:00:00Z General Mills’ research and development team for Annie’s soups wanted to use a natural chicken flavoring with yeast extract—a flavor enhancer that many Annie’s consumers avoid because they fear it spurs overeating. Annie’s Inc., Look How You’ve Grown 2015-09-16T04:00:00Z Gates, one of the most prolific players at his position in league history, is docked four games under the performance enhancers policy. Bell, Gates among 26 suspended NFL players 2015-09-09T04:00:00Z The day’s lesson was meant to be a “skill enhancer,” focussing on improving the officers’ interpersonal skills. What’s New About Bill Bratton’s N.Y.P.D.? 2015-09-07T04:00:00Z Owner Michael Schlesinger says the stuff was just soil enhancer for landscaping, but some homeowners thought it was laid down to annoy residents who fought his plans to build hundreds of homes on the property. Southern California golf club owner agrees to pay $100,000 to settle stink over chicken manure 2015-08-29T04:00:00Z This correlation may reflect modulation of gene expression by transposon-derived enhancers or a greater tolerance for transposon insertion near genes with less complex patterns of tissue-specific gene regulation. The octopus genome and the evolution of cephalopod neural and morphological novelties : Nature : Nature Publishing Group 2015-08-11T04:00:00Z It is also a significant career enhancer even for officers who do not serve in combat units. Army Ranger School a Test for Women in Combat Roles 2015-08-07T04:00:00Z My basket is filled with flavor enhancers but no main meals. A Brooklyn Grocery's Last Night 2015-08-07T04:00:00Z And just about every horse running in the Triple Crown races this year was running on Lasix, a drug that is widely recognized as a performance enhancer. Dozens of racing horses die every week because of drug abuse 2015-08-02T04:00:00Z “Baggage fees that are revenue enhancers for airlines are just taking advantage of you.” More Fees Propel Airlines’ Profits, and Embitter Travelers 2015-07-27T04:00:00Z Promptly voting in Bonds, whom most people believe did take performance enhancers late in his career, would at least establish a precedent for admitting those locked in that holding pen of grudge-holding and guesswork. It’s Time to Reconsider Barry Bonds for the Hall of Fame 2015-07-24T04:00:00Z It’s also been used, often illegally, as a “cognitive enhancer” that can make the user more alert, focused and able to concentrate for hours on end. Anti-doping in e-sports: World's largest gaming organization will test for PEDs 2015-07-23T04:00:00Z The following four tracks contain green blocks indicating the location of super enhancers, enhancers and hypomethylated DMRs in the aorta, respectively. Human body epigenome maps reveal noncanonical DNA methylation variation : Nature : Nature Publishing Group 2015-05-31T04:00:00Z In fact, he’s not convinced these drugs are cognitive enhancers at all. The Problem of Artificial Willpower 2015-07-07T04:00:00Z “I think of it like these performance enhancers that some stellar athletes use: it bumps up performance, but not for ever.” The hunt for the world’s missing carbon 2015-06-29T04:00:00Z This is not to condone the use of performance enhancers, or to rewrite the damage done by their past infestation. It’s Time to Reconsider Barry Bonds for the Hall of Fame 2015-07-24T04:00:00Z Their comments beg the obvious question: how many more British distance runners were offered thyroid medication as a performance enhancer? Alberto Salazar has admirers but he may tarnish Mo Farah’s reputation 2015-06-08T04:00:00Z The following four tracks contain green blocks indicating the location of super enhancers, enhancers and hypomethylated DMRs in the aorta, respectively. Human body epigenome maps reveal noncanonical DNA methylation variation : Nature : Nature Publishing Group 2015-05-31T04:00:00Z Treating that alienation with a motivation enhancer, rather than re-evaluating the course of your life, seems like a bad idea. The Problem of Artificial Willpower 2015-07-07T04:00:00Z Maggi was also undergoing tests for high levels of monosodium glutamate or MSG, a common but harmful chemical ingredient used as a flavor enhancer in packaged and fast foods worldwide. Nestle Takes Maggi Instant Noodles Off Shelves Across India 2015-06-05T04:00:00Z “Nestlé claims its products are not harmful but we found lead in the taste enhancer powder,” Singh said. India withdraws Maggi noodles from shops in mounting food-safety scare 2015-06-03T04:00:00Z "Nestle claims its products are not harmful but we found lead in the taste enhancer powder," Singh said. Maggi noodles ordered off India's shelves due to lead level 2015-06-03T04:00:00Z The tests also detected the chemical flavor enhancer monosodium glutamate, or MSG, which is not mentioned in the product’s list of ingredients. Maggi noodles ordered off India’s shelves due to lead level 2015-06-03T04:00:00Z Vrecko notes these and other, similar descriptions and asks just how cognitive these “cognitive” enhancers really are. The Problem of Artificial Willpower 2015-07-07T04:00:00Z At that point, he not been linked to the use of performance enhancers. For Alex Rodriguez, a Milestone Looms, and Perhaps a Dispute 2015-04-10T04:00:00Z The tests also detected the chemical flavour enhancer monosodium glutamate, or MSG, which is not mentioned in the product’s list of ingredients. India withdraws Maggi noodles from shops in mounting food-safety scare 2015-06-03T04:00:00Z To improve the taste, chill it first or ask your doctor whether it’s okay to add lemon, lime, ginger or a flavor enhancer such as Crystal Light. How to have a safe and smart colonoscopy 2015-03-30T04:00:00Z “Nestle claims its products are not harmful but we found lead in the taste enhancer powder,” Singh said. Maggi noodles ordered off India’s shelves due to lead level 2015-06-03T04:00:00Z Seven of the counts to which Sullivan pleaded guilty are so-called "sentence enhancer" crimes, authorities said, including being a convicted felon in possession of a weapon, and other crimes of violence. Colorado carjacker pleads guilty to crime spree caught on live TV 2015-03-24T04:00:00Z “La Niña is kind of the enhancer, but it’s not the clearest enhancer,” Allen said. Experimental Forecast Projects Tornado Season 2015-03-16T04:00:00Z Perhaps the reason drug abuse is prevalent among physicians is that drugs are perceived as performance enhancers: no doctor wants to be seen as drowsy or moody. Readers Respond to "The Neuroscience of Meditation" 2015-03-08T05:00:00Z The solution in Wisconsin will have to be a mix of spending reductions, slowing down projects and what he called “some type of revenue enhancer” constituents will accept, he said. Loss of federal highway aid adds to Wisconsin road woes 2015-02-21T05:00:00Z Wray is particularly interested in DNA segments called enhancers, which control the activity of genes nearby. Human DNA enlarges mouse brains 2015-02-19T05:00:00Z The authors found that these variants are often located in or near enhancers or promoters. Epigenomics: Roadmap for regulation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z The only exception was significant switching between transcribed states and active promoter and enhancer states, possibly due to alternative usage of promoters22 and enhancers60 embedded within transcribed elements. Integrative analysis of 111 reference human epigenomes : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Shown to the right is the level of mRNA-seq data for each allele of the FAM65B gene, the level of histone acetylation at the allelic enhancer bait region. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z We calculate the significance using a binomial P value, in which the probability of success in the changing enhancers is based on the frequency in the unchanging enhancers. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease : Nature : Nature Publishing Group 2015-02-17T05:00:00Z They first inserted each enhancer into embryonic mice to learn whether it really did turn genes on. Human DNA enlarges mouse brains 2015-02-19T05:00:00Z The authors developed computational models to predict the transcription factors that bind to core neural-differentiation enhancers, as well as those that bind enhancers of distinct neural lineages only. Epigenomics: Roadmap for regulation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z In contrast, for repressive factors and CTCF, positional biases were found in large numbers of tissues, even when the motifs were not enriched in active enhancers. Integrative analysis of 111 reference human epigenomes : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Next, these modification signals in all cell lines were tested to predict enhancers. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z The mapped enhancer regions were annotated with their chromatin state in human hippocampus, and across all 127 cell types and tissues, using BEDTools47. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease : Nature : Nature Publishing Group 2015-02-17T05:00:00Z And, Wray says, given the growing ability of researchers to study enhancers and other DNA in mice, “my guess is there are probably other stories like this in the works.” Human DNA enlarges mouse brains 2015-02-19T05:00:00Z Enhancers are activated through interactions with transcription factors, which recognize and bind to specific DNA sequences within the enhancer region. Epigenomics: Roadmap for regulation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Allelic histone acetylation at enhancers is highly specific to individual genotypes, and often occurs near sequence variants that alter transcription factor binding, suggesting cis-acting sequence drivers for at least a subset of these regions61, 72. Integrative analysis of 111 reference human epigenomes : Nature : Nature Publishing Group 2015-02-17T05:00:00Z After constructing two 1 by 10 vectors for both allelic gene and allelic enhancer, we calculated the Pearson correlation coefficient between them. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z The results for the consistently increasing enhancers were slightly more significance when using a hypergeometric test instead of the binomial. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Bar graph shows the percentage of MS SNPs overlapping immune enhancers using different algorithms for calling candidate causal SNPs. Genetic and epigenetic fine mapping of causal autoimmune disease variants : Nature : Nature Publishing Group 2014-10-28T04:00:00Z Therefore, the delineation of a particular cell's active enhancer repertoire provides a powerful means of predicting the transcription factors required for that cell's identity. Epigenomics: Roadmap for regulation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Interestingly, inflammatory bowel disease and ulcerative colitis variants show enrichment in both immune and gastrointestinal enhancer marks, suggesting that dysregulation of both organs may underlie disease predisposition. Integrative analysis of 111 reference human epigenomes : Nature : Nature Publishing Group 2015-02-17T05:00:00Z We observe that regions that are involved gain of interactions tend to contain more enhancers in differentiated lineages compared to H1 cells. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z We define enhancers based on peaks of H3K27ac labelled by the enhancer chromatin state. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Nearly all of the autoimmune diseases preferentially mapped to enhancers and promoters active in CD4+ T-cell subpopulations. Genetic and epigenetic fine mapping of causal autoimmune disease variants : Nature : Nature Publishing Group 2014-10-28T04:00:00Z This suggests that there is more to an enhancer than a 'simple' collection of sites of transcription-factor binding embedded in the composition of its DNA sequence. Epigenomics: Roadmap for regulation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z A large number of metabolic trait variants are enriched in liver enhancer marks, including LDL, HDL, total cholesterol, lipid metabolism phenotypes, and metabolite levels83, 84. Integrative analysis of 111 reference human epigenomes : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Random enhancers were selected to match the read coverage of allele-biased enhancers. c, Number of allele specific genes linked to concordantly biased allele specific enhancers. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z We used a hypergeometric test to evaluate whether or not these external annotations were enriched in the set of increased-level or decreased-level enhancers relative to the enhancers whose levels do not change. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Nonetheless, their modest overlap with eQTLs and their striking correspondence to enhancers suggest that most disease variants exert subtle and highly context-specific effects on gene regulation. Genetic and epigenetic fine mapping of causal autoimmune disease variants : Nature : Nature Publishing Group 2014-10-28T04:00:00Z Finally, although the DNA sequences found in cell-specific enhancers provides clues to the identities of the transcription factors that regulate enhancer activation, functional roles must be validated experimentally. Epigenomics: Roadmap for regulation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Several cardiac traits were enriched in heart tissue enhancers, including the PR heart repolarization interval, blood pressure and aortic root size. Integrative analysis of 111 reference human epigenomes : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Predicted enhancers, H3K27ac, RNA-seq, and RefSeq gene information are shown together. b, Box plots showing the reproducibility of predicted enhancer–promoter interactions between two biological replicates for each chromosome with different P value cutoffs. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z In this case, only enhancers that map to human are taken to be the background. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease : Nature : Nature Publishing Group 2015-02-17T05:00:00Z In contrast, the candidate causal SNPs identified by PICS, but missed by both of the other methodologies, were significantly enriched for immune enhancers. Genetic and epigenetic fine mapping of causal autoimmune disease variants : Nature : Nature Publishing Group 2014-10-28T04:00:00Z Our results therefore suggest that genetic variations are probably responsible for allelic enhancer activities and consequently allelically biased gene expression. Integrative analysis of haplotype-resolved epigenomes across human tissues : Nature : Nature Publishing Group 2015-02-17T05:00:00Z We clustered motifs using a 0.75 correlation cutoff resulting in 300 motif clusters68 and selected for each motif cluster the motif with the highest enrichment in any enhancer module for further analysis. Integrative analysis of 111 reference human epigenomes : Nature : Nature Publishing Group 2015-02-17T05:00:00Z The regions with more lineage-specific enhancers in differentiated lineages are enriched by gain of interactions. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Decreased-level enhancers and promoters were targeted by different regulators, suggesting distinct regulatory programs. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Bar graph shows the percentage of MS SNPs overlapping immune enhancers using different algorithms for calling candidate causal SNPs. Genetic and epigenetic fine mapping of causal autoimmune disease variants : Nature : Nature Publishing Group 2014-10-28T04:00:00Z KS test was performed for P value calculation. b, Allelically biased enhancers were tested in thymus from donor 1 and pancreas from donors 2 and 3. Integrative analysis of haplotype-resolved epigenomes across human tissues : Nature : Nature Publishing Group 2015-02-17T05:00:00Z We found that enhancers and promoters maintained their identity, except for a small subset of regions switching between enhancer signatures and promoter signatures61. Integrative analysis of 111 reference human epigenomes : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Random enhancers were selected to match the read coverage of allele-biased enhancers. c, Number of allele specific genes linked to concordantly biased allele specific enhancers. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z We then calculated enrichment of human orthologues of different categories CK-p25 enhancers relative to stable regions and used a binomial P value to estimate the significance. Conserved epigenomic signals in mice and humans reveal immune basis of Alzheimer/'s disease : Nature : Nature Publishing Group 2015-02-17T05:00:00Z The enrichment of candidate causal variants within enhancers suggests that they affect disease risk by altering gene regulation, but does not distinguish the underlying mechanisms. Genetic and epigenetic fine mapping of causal autoimmune disease variants : Nature : Nature Publishing Group 2014-10-28T04:00:00Z KS test was performed for P value calculation. b, Allelically biased enhancers were tested in thymus from donor 1 and pancreas from donors 2 and 3. Integrative analysis of haplotype-resolved epigenomes across human tissues : Nature : Nature Publishing Group 2015-02-17T05:00:00Z We found that enhancers showing coordinated differences in multiple marks were enriched near genes showing common tissue-specific expression, and common knockout phenotypes based on their mouse orthologues. Integrative analysis of 111 reference human epigenomes : Nature : Nature Publishing Group 2015-02-17T05:00:00Z To systematically study allelic enhancers, we combined several enhancer marks to obtain a combined acetylation bam file. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z They were also able to pinpoint active regulatory DNA called enhancers, which are under the sway of epigenetic tags and control where and when different genes are expressed. Massive project maps DNA tags that define each cell's identity 2015-02-18T05:00:00Z To compare enhancer regions across different cell types, we first subdivided regions of the genome that were marked as enhancers into enhancer segments ~1 kb in size. Genetic and epigenetic fine mapping of causal autoimmune disease variants : Nature : Nature Publishing Group 2014-10-28T04:00:00Z These sites possessed histone modification signatures of active enhancers in some tissue/cell types but were enriched with active promoter marks in others. Integrative analysis of haplotype-resolved epigenomes across human tissues : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Fasting glucose was most enriched for pancreatic islet enhancer marks and insulin-like growth factors in placenta, consistent with their endocrine regulatory roles85, 86. Integrative analysis of 111 reference human epigenomes : Nature : Nature Publishing Group 2015-02-17T05:00:00Z For evaluating allelic enhancers, we obtained readout for enhancers defined in ref. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z The work indicates that enhancers play an important role in shaping the 3D structure of the DNA, the team reports. Massive project maps DNA tags that define each cell's identity 2015-02-18T05:00:00Z Although these enhancers frequently reside within extended clusters, their distinct regulatory patterns and phenotypic associations suggest they represent independent functional units. Genetic and epigenetic fine mapping of causal autoimmune disease variants : Nature : Nature Publishing Group 2014-10-28T04:00:00Z Furthermore, if allelic imbalances of enhancer activities indeed contribute to allelically biased gene expression, we expect that chromatin states at enhancers will be concordant with the expression of their targets. Integrative analysis of haplotype-resolved epigenomes across human tissues : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Also on Saturday, the Orioles slugger Chris Davis said he used Adderall last season not as a performance enhancer but rather as a way to cope with an oblique muscle injury. Blue Jays Pursued Executive 2015-02-01T05:00:00Z If more than one bin of ASM overlapped an enhancer, we checked to see whether the patterns of ASM were concurrent between all bins. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Further analyses indicated that enhancers specific to particular cell types "appear to be where the major action is for disease," LaSalle says. Massive project maps DNA tags that define each cell's identity 2015-02-18T05:00:00Z Notable examples include SNPs associated with Alzheimer’s disease and migraine, which map to enhancers and promoters active in brain tissues, and SNPs associated with fasting blood glucose, which map to elements active in pancreatic islets. Genetic and epigenetic fine mapping of causal autoimmune disease variants : Nature : Nature Publishing Group 2014-10-28T04:00:00Z Also Saturday, suspended slugger Chris Davis says his use of Adderall last season was not as a performance enhancer but rather a way to cope with injuries and struggles at the plate. Duquette puts Toronto in past, focuses on improving Orioles 2015-01-31T05:00:00Z All the panelists hailed the product, calling it a “yield enhancer” that would increase profits. A Push for a Greater Government Role in Housing Finance 2015-01-28T05:00:00Z For each identified allele-biased enhancer, we selected 100 random enhancers from the same coverage bin. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z These enhancers are often located where large-scale population studies of genetic variation—so-called genome-wide association studies—pinpoint an increased risk of disease. Massive project maps DNA tags that define each cell's identity 2015-02-18T05:00:00Z One of its discoveries, Sweetmyx, is a sweetness enhancer; it might allow Pepsi to use less sugar to get the same taste. A Perfect Sugar Substitute Would Save Lives and Make Billions. Why Can't We Make One? 2015-01-16T05:00:00Z Proponents see big potential for the soil enhancer, which is produced by heating biological material — such as husks and other agricultural waste — in a low-oxygen chamber. Agriculture: State-of-the-art soil 2015-01-13T05:00:00Z “Since beliefs are strong performance enhancers, I would recommend compression clothing to persons who believe in the performance-enhancing effect,” he said. Can Compression Clothing Enhance Your Workout? 2015-01-14T05:00:00Z This limits the effects of local variation in heterozygosity rates throughout the genome on the likelihood of identifying allele-biased enhancers near allele-biased genes. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z “It’s an alcohol enhancer,” added her friend Sonji Helena, also 25, of Atlantic City. Cigarettes out, hookahs in at Philadelphia clubs 2015-01-12T05:00:00Z The annual vote may also foreshadow future prospects of dominant players such as Barry Bonds and Roger Clemens, who have been snubbed so far over suspected use of performance enhancers. Randy Johnson could lead large class into Hall of Fame 2015-01-05T05:00:00Z This bodes well for PepsiCo, which holds exclusive rights to use this flavor enhancer in its soft drinks. The Year That Was: PepsiCo 2014-12-30T05:00:00Z Nicer looking photos from your friends means a more enjoyable Facebook all around, so it's good news for everyone if Facebook's photo enhancer works. Facebook has started automatically enhancing your mobile photos 2014-12-16T05:00:00Z At a given P value cutoff, we defined enhancer–promoter interactions. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z "I’d had my fun and experimented with my fair share of mood enhancers. I knew by the second sip of the drink Cosby had given me that I’d been drugged—and drugged good." Model Beverly Johnson says in Vanity Fair that Bill Cosby drugged her 2014-12-12T05:00:00Z Sometimes, they activate genes that force the cell to commit suicide; in others, they bind to distant control regions called enhancers that encourage the activation of genes known to be involved in the reprogramming process. Stem cells: The black box of reprogramming 2014-12-09T05:00:00Z As a result, Bonds and Clemens are being dragged down by their ties to performance enhancers. In Hall of Fame Vote, Split Tickets and Tainted Candidates 2014-12-04T05:00:00Z Although some of the effects like ‘eye enhancer’ and ‘face contour’ – which makes your face slimmer – perpetuate unsecurely obsessive vanity that seems to have gripped the selfie crazed. Nokia Lumia 830 Vs HTC Desire EYE: 2014's Best Mid-Range Phones 2014-12-04T05:00:00Z Shown to the right is the level of mRNA-seq data for each allele of the FAM65B gene, the level of histone acetylation at the allelic enhancer bait region. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Charged with social and cultural meanings, it is a powerful enhancer, sending signals that may not really reflect an entity's true nature. How the Color Red Influences Our Behavior 2014-11-24T05:00:00Z This observation was further validated by in vivo enhancer assays in transgenic mice. Principles of regulatory information conservation between mouse and human : Nature : Nature Publishing Group 2014-11-18T05:00:00Z Future studies will be necessary to determine whether retroviral elements at or near enhancers are generally involved in driving tissue-specific gene expression programs in different mammalian species. A comparative encyclopedia of DNA elements in the mouse genome : Nature : Nature Publishing Group 2014-11-18T05:00:00Z But as more Americans pay attention to what they eat, they are demanding to know what those natural and artificial flavors - and other ingredients added as flavor enhancers - are made of. Colorado Editorial Roundup 2014-11-19T05:00:00Z If there were divergent patterns between ASM bins at an enhancer, these enhancers were excluded. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z She assured me that she passed her drug test, unless gumbo is considered a performance enhancer. Running the New York City Marathon at Age 60 2014-11-02T04:00:00Z The in vivo enhancer activity assays were conducted at the E.O. Principles of regulatory information conservation between mouse and human : Nature : Nature Publishing Group 2014-11-18T05:00:00Z Instead of gene expression levels, we selected the histone modification H3K27ac as an indicator of promoter or enhancer activity as previously reported56. A comparative encyclopedia of DNA elements in the mouse genome : Nature : Nature Publishing Group 2014-11-18T05:00:00Z Pepsi recently announced that it would start to use Sweetmyx, a flavor enhancer in its drinks starting this year. Coca-Cola and rivals promise health changes but are profits the real reason? 2014-10-01T04:00:00Z This was accomplished by binning all enhancers into increments of 50 sequencing reads, from 0 to 49, 50 to 99, etc, up to 1,700 reads. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Others, like the “focus enhancers” — effectively black mesh laundry bags worn over masks — were born over a few beers. Goalie guru Mitch Korn helps man the post for the Washington Capitals The red line shows the fraction of TF OSs at which occupancy is conserved within each bin of Shannon index. b, Association between occupancy conservation and enhancer usage across several tissues. Principles of regulatory information conservation between mouse and human : Nature : Nature Publishing Group 2014-11-18T05:00:00Z While the effectiveness of Lasix is in no doubt, question marks over exactly how it manages to improve racehorse performance lead to concerns about its role as a potential performance enhancer. Lasix: the drug debate which is bleeding US horse racing dry 2014-08-31T04:00:00Z But in a climate of fallout from concussions and other injurious long-term effects of playing this sport, scheduling expansion now seems settled on another revenue enhancer, adding wild-card playoff teams to the postseason. Preseason N.F.L. Games May Not Count, but They Can Have Meaning 2014-08-29T04:00:00Z The regions with more lineage-specific enhancers in differentiated lineages are enriched by gain of interactions. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z In contrast, the enhancer mark H3K4me1 is down-weighted, perhaps reflecting that signals for most human enhancers are not near the TSS. Comparative analysis of the transcriptome across distant species : Nature : Nature Publishing Group 2014-08-26T04:00:00Z The stained embryo images are highlighted by activity in different tissues: light pink for those showing enhancer activity only in heart and vascular tissues, darker pink for those with activities in other tissues. Principles of regulatory information conservation between mouse and human : Nature : Nature Publishing Group 2014-11-18T05:00:00Z Moreover, these context-specific HOT regions are specifically enriched for enhancers in matching cell types or developmental stages. Comparative analysis of regulatory information and circuits across distant species : Nature : Nature Publishing Group 2014-08-26T04:00:00Z In particular, these regions seem to segregate to enhancer and promoter regions with different chromatin architectures and different sets of transcription factors. Regulatory analysis of the C. elegans genome with spatiotemporal resolution : Nature : Nature Publishing Group 2014-08-26T04:00:00Z We observe that regions that are involved gain of interactions tend to contain more enhancers in differentiated lineages compared to H1 cells. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Home runs kept coming at inflated rates, and sluggers looked more like body builders as use of steroids and other performance enhancers began to make a mockery of the record book. Selig oversaw prosperity and both ends of Steroids Era 2014-08-14T04:00:00Z The stained embryo images are highlighted by activity in different tissues: light pink for those showing enhancer activity only in heart and vascular tissues, darker pink for those with activities in other tissues. Principles of regulatory information conservation between mouse and human : Nature : Nature Publishing Group 2014-11-18T05:00:00Z They say Lasix is therapeutic, but Lasix is a performance enhancer. 'Drugs and dead horses': US racing reels after Peta video broadside 2014-08-03T04:00:00Z But three managers were also inducted, and at least one benefited from star players’ use of performance enhancers. Letters to the Sports Editor 2014-08-02T04:00:00Z Predicted enhancers, H3K27ac, RNA-seq, and RefSeq gene information are shown together. b, Box plots showing the reproducibility of predicted enhancer–promoter interactions between two biological replicates for each chromosome with different P value cutoffs. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Expanding pharmaceutical industries could design many more sedatives, stimulants and performance enhancers for armies - but the U.S. at least will likely be cautious about this. 1914-2014: Weapons of the Next Great War 2014-08-01T04:00:00Z The red line shows the fraction of TF OSs at which occupancy is conserved within each bin of Shannon index. b, Association between occupancy conservation and enhancer usage across several tissues. Principles of regulatory information conservation between mouse and human : Nature : Nature Publishing Group 2014-11-18T05:00:00Z Strawbridge disagrees with those who argue that certain drugs are therapeutic, rather than performance enhancers: 'Drugs and dead horses': US racing reels after Peta video broadside 2014-08-03T04:00:00Z The codon affected by the Y1003* mutation is predicted to disrupt multiple splicing enhancer sequences, but the mechanism of skipping remains unknown in this case. Comprehensive molecular profiling of lung adenocarcinoma : Nature : Nature Publishing Group 2014-07-08T04:00:00Z These local changes are best predicted by changes in levels of H3K4me1 and the density of enhancer elements. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Both riders were later sanctioned in connection with banned performance enhancers. With Nibali in command, Tour is about 2nd place 2014-07-25T04:00:00Z Conservation of occupancy is consistently higher in the promoter regions and lower in distal regions for almost all TFs, suggesting that the promoters may be under stronger selection than distal enhancers. Principles of regulatory information conservation between mouse and human : Nature : Nature Publishing Group 2014-11-18T05:00:00Z Those players deserve recognition as the best of their time despite being linked to performance enhancers, said La Russa, who will join five other new inductees at Cooperstown this weekend. Inductee La Russa says let steroid era players in Hall 2014-07-25T04:00:00Z Brain tissues used to define enhancers consist of heterogeneous populations of cells. Biological insights from 108 schizophrenia-associated genetic loci : Nature : Nature Publishing Group 2014-07-21T04:00:00Z Final interaction scores were defined as summation of interaction frequencies between promoter and enhancer with multiple window sizes. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z The main problem, law enforcement officials say, remains the perception that the cameras are used as revenue enhancers. What happens when speed cameras no longer generate millions of dollars? Is that possible, you might ask? There’s little scientific evidence, however, to support abstinence as a performance enhancer. A World Cup quandary: sex or abstinence 2014-06-04T04:00:00Z There's little scientific evidence, however, to support abstinence as a performance enhancer. A World Cup quandary: sex or abstinence 2014-06-04T04:00:00Z We defined cell and tissue type enhancers as the top 10% of enhancers with the highest ratio of reads in that cell or tissue type divided by the total number of reads. Biological insights from 108 schizophrenia-associated genetic loci : Nature : Nature Publishing Group 2014-07-21T04:00:00Z According to interaction distance, enhancer–promoter interaction scores were calculated between target and off-target gene relationships. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Hill was suspended for violating the performance enhancers policy two years ago, missing four games. Giants safety Hill suspended 6 games 2014-05-30T04:00:00Z Speed-reading is either a productivity enhancer or a gimmick that lets people gobble up content without really understanding or retaining what they’ve read. Speed-Reading Reborn for Smartphones, Smartwatches 2014-05-28T04:00:00Z Appearance enhancers: “There is no shame in defying your age,” writes Ryan. How Older Job Seekers Can Look Sharp In Interviews 2014-05-27T04:00:00Z We defined cell and tissue type enhancers as the top 10% of enhancers with the highest ratio of reads in that cell or tissue type divided by the total number of reads. Biological insights from 108 schizophrenia-associated genetic loci : Nature : Nature Publishing Group 2014-07-21T04:00:00Z Of note, this allele-biased enhancer forms no specific contacts with any allelic genes. h, Similar to d, but for an enhancer located near the MT2A gene. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z In the later stages of life, music therapy is not as rehabilitative as it is for younger populations, but Bumanis says it’s a “quality-of-life enhancer.” Therapists use music to deliver treatment 2014-05-26T04:00:00Z Without revealing what the substance was, Konopka defended himself by saying it was an ingredient found in an over-the-counter product and not used as a performance enhancer. NHL suspends Sabres F Konopka 20 games 2014-05-15T04:00:00Z Nicotine is the most reliable cognitive enhancer that currently known. May/June 2014 Scientific American MIND News Ticker 2014-04-28T16:30:00Z And now new research adds “memory enhancer” to the list. Study: Green Tea Boosts Working Memory 2014-04-15T02:58:00Z There are no specific interactions between the allelic enhancer and the MT2A gene. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Asked about the effect of Rodriguez’s suspension on the team, Strohmeyer said, “He’s kind of outlived his usefulness, regardless of his issues with steroids and performance enhancers.” Though Sad to See Him Go, Yankees Fans Support Jeter’s Decision to Leave 2014-04-07T11:00:00Z Not only does even that now seem elusive, but the peace process is also hung up on the issue of prisoner releases — a matter that has turned out to be a confidence destroyer, not enhancer. We Can’t Trade Pollard for Peace 2014-04-01T15:12:25Z |
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