| 单词 | endpoint |
| 例句 | “The big thing you learn is there’s not an endpoint,” Wayne says. Drama High 2013-09-26T00:00:00Z As far as the endpoints, we don't have a full stop written down at this stage. "All Creatures Great and Small" writer on bringing "bittersweet" comforts of WWII to the Dales 2023-02-20T05:00:00Z There is no endpoint, only success and failure and a dedication to jumping back into play. "Billions" is better than "Game of Thrones" at studying power, hate and corruption 2019-05-05T04:00:00Z If it had already peaked by the time Bennett wrote about it, in the fall of 2015, we can locate its hard endpoint about a year later, in November of last year. The Personal-Essay Boom Is Over 2017-05-18T04:00:00Z Really: who better to stand at the endpoint of all these tangled historical roads than Kraftwerk? Kraftwerk at Tate Modern, night two: Radio-Activity 2013-02-08T14:53:56Z If there was a beginning to the end of this era, and we are at the endpoint now, it was probably Letterman's arrival at CBS in 1993. Regis, Carson, Letterman, Conan ? late-night wars chronicled in new book 2011-01-27T00:53:04Z RoboCop, for the love of God, because kids have traditionally always gone crazy for pitch-black satires dealing with the logical endpoint of military-industrial capitalism. 2 Fast 2 Furious 2 Animated: in praise of the cartoon spin-off series 2018-04-25T04:00:00Z It’s certainly the logical endpoint for a character like Zack Morris, a sneering, smirking, smug little rich boy who skated through life on his own privileged secretions. Saved by the Bell: will the revival be 2020's most depressing show? 2019-09-18T04:00:00Z And my mom and dad were waiting at the wrong 19.6-mile endpoint. Camping According to Your Taste 2015-04-01T04:00:00Z If Hollywood can make that so, then instead of an endpoint, Yeoh’s historic Oscar will serve as a long-needed new beginning. After Her Oscar Win, Will Michelle Yeoh Get to Lead Again? 2023-03-15T04:00:00Z “It’s art that is not just about the endpoint,” she explains. What happens when two artists move into an unfinished museum for 10 days of 'Performance Lessons' 2016-10-28T04:00:00Z And scientists are generally looking for what they call “surrogate endpoints,” like increased cholesterol rather than death from heart disease, since it’s impractical to keep a trial going until people die. Perspective | Here’s what the government’s dietary guidelines should really say 2019-03-25T04:00:00Z It’s a party every time but one with a clear and blessedly early endpoint. Skiing the Alps, Making It My Own 2016-11-29T05:00:00Z The museum is building a boathouse for it near the airport on Lake Pontchartrain, the eventual endpoint of the barge trip that began on Saturday. New Victory for World War II PT Boat: Restored and Museum-Ready 2016-11-21T05:00:00Z And “American Idol,” the series that made Cowell a star, seems to be nearing its endpoint. Why did people stop caring about “American Idol”? 2014-05-22T04:00:00Z There are various formal and informal designations of the Mohawk Trail’s endpoints, but the most rewarding miles lie between North Adams, in the northern Berkshires, and Greenfield. Journeys: Driving the Mohawk Trail in Massachusetts 2012-10-04T16:29:55Z Seen in that light, underwear on Fifth Avenue was probably always a logical endpoint in a progressive blurring of distinctions between public and private. Suddenly It’s Bare Season 2021-07-22T04:00:00Z “It is a journey. There’s no endpoint, actually, as we continue to explore and try to find new things in even music that we’ve played a lot.” Philharmonic Announces 2015-16 Concerts and Residencies 2015-01-21T05:00:00Z Not because it’s enjoyable or fun or even particularly good, but because it very clearly signals the logical endpoint of the televised singing competition. The Masked Singer: the year's strangest TV show is already here 2019-01-11T05:00:00Z The piece, titled “Comedian,’’ was the endpoint in a creative process that saw him cycling through renditions of the fruit in resin and bronze, before settling on the real thing. The $120,000 Banana Wins Art Basel 2019-12-06T05:00:00Z More and more series were naturally driven toward an endpoint, like “Lost,” for which ABC took the unusual step of setting a three-season glide path to its finale. ‘The Americans’ Finished? Thank You for Killing My Favorite Show 2016-05-26T04:00:00Z It’s a stinging indictment of what it’s become fashionable to call “late capitalism,” as if anyone had an idea of its endpoint. She Dropped Everything to Meet the K-Pop Star of Her Fantasies 2023-03-14T04:00:00Z If a trial does not succeed in meeting its primary endpoint, it is considered a failure, even if there is evidence of other beneficial effects. Medical Terms You Need To Know 2010-08-23T10:00:00Z “It’s there very deliberately to ask, ‘Is secularism the endpoint?’ ” Norton’s Latest Anthology Explores World Religion 2014-11-02T04:00:00Z Still, Istria’s fame does not approach that of Dubrovnik at the southern endpoint of Croatia or of Trieste to the north. Sipping the Pleasures of Istria 2013-08-22T19:03:39Z Her chapter on superhero comics goes narrow, treating antihero stories such as “Watchmen” and “The Boys” as the endpoints of the cape comics genre. What Even Is a Nerd Anymore? 2022-10-12T04:00:00Z This is the logical endpoint of the American dance-music explosion of the last decade, which was almost certainly never going to end in a nightclub. Review: The Chainsmokers Find That Pop Is an Awkward Fit 2017-04-12T04:00:00Z "Luther" has given its audience at least three natural endpoints. For Idris Elba's sake, let "Luther" retire 2023-03-12T05:00:00Z Always, the endpoint is California, “this endlessly striving state at the end of America, where everyone was always going somewhere, and fast.” From Digging for Gold to Drinking It, in a Novel of American Striving 2021-04-06T04:00:00Z In the real world, it's relatively easy to arrive at a natural endpoint to the evening. My virtual social life is exhausting: Turns out Zoom cocktail hours can burn you out, too 2020-04-03T04:00:00Z Getting into a series is a commitment, and one that almost always presumes there’ll be some kind of endpoint. Louis C.K.'s 'Horace and Pete' Shows Independent TV's Limits 2016-04-12T04:00:00Z It is radical, at least in a structural sense, to take the endpoint of so much other entertainment — finding true love — and make it the starting line. True Love? On TV, There’s an App for That. 2021-04-21T04:00:00Z In his eyes, Trump is a logical endpoint to what started with Hart. When a Collision Between Politics and Sex Shocked Americans 2018-10-31T04:00:00Z We seem to have reached a kind of endpoint in western culture and to be on the edge of something else, brought about by the information age and the global economic crisis. Edinburgh festival turns back clock 50 years to literary debates of 1962 2012-08-10T15:45:44Z We’re conditioned to think of an Oscar win as the endpoint to a journey. After Her Oscar Win, Will Michelle Yeoh Get to Lead Again? 2023-03-15T04:00:00Z From those two endpoints, Dafoe began to fill in his career with whatever he found fascinating, be it erotic thrillers with Madonna and action films against Ice Cube, or Wes Anderson wundercabinets and Marvel flicks. Willem Dafoe: 'With success comes certain things that corrupt you' 2018-11-19T05:00:00Z Even though there were no dwarves, Harfoots or Elrond this week, it sure seemed like we were reaching a natural endpoint. ‘The Lord of the Rings: The Rings of Power,’ Season 1, Episode 6: Doom 2022-09-30T04:00:00Z So putting the returned bronzes on display isn’t the endpoint to you, but a beginning? A New Museum to Bring the Benin Bronzes Home 2020-11-13T05:00:00Z And then came his 2016 comeback, which felt like a logical endpoint. Ricky Gervais isn't the Golden Globes host we want – but the one we deserve 2020-01-03T05:00:00Z Others were optimistic that the evening was not an endpoint. A Chinatown Loft Party in the Spirit of Warhol’s Factory 2018-09-12T04:00:00Z "A lot of people who I think build startups or companies think that selling the company or going public is this endpoint," he said. Time honor caps celebrity-making of Zuckerberg 2010-12-16T07:01:04Z And yet the show’s saving grace was always knowing that an endpoint was in sight. The Good Place: was this the most devastating TV finale ever? 2020-02-04T05:00:00Z The Roadium is a typical endpoint for the city's abandoned storage unit hauls, so a lot of film and music industry gems end up among its vendor booths. Leo Nocentelli’s long-lost folk-funk album sees the light of day, 50 years later 2021-11-17T05:00:00Z Yet that slow pace can have benefits: the first two seasons took time to reach their climaxes, but when those endpoints came they were both explosive and fully earned. Boardwalk Empire: a slow-burner with a fierce flame 2012-09-28T14:15:00Z Last night’s episode started in the middle of a frantic scene, rolled the opening credits, then went back to the beginning to show us how we got to that endpoint. The Walking Dead Watch: 18 Miles Out 2012-02-27T13:45:51Z This Biennale would have been a failure if reversing the old gender bias were its mere endpoint. Looking Inward, and Back, at a Biennale for the History Books 2022-04-30T04:00:00Z There are echoes here of the early days of cancer research, when it too seemed to be a shared endpoint of several possible causes, including infections. Does our immune system hold the key to beating Alzheimer’s disease? 2019-03-03T05:00:00Z The date lasted a bit over an hour, stopping at what both felt was a natural endpoint. Date Lab: He was prepared to get roasted 2021-05-07T04:00:00Z At times, especially in the depths of these nightmarish sequences, I admired Riker’s audacity more than I enjoyed following his logic to its gruesome endpoints. Body Hopping for a Better View of America 2018-11-09T05:00:00Z But with this, you get to that endpoint and it's, "You were leading me here all along." Harlan Coben on why even bestselling authors get those self-loathing writer blues 2019-03-25T04:00:00Z Then he drove that line, from the northwest corner of the continental United States to its southeastern endpoint—alone. My father loved epic solo road trips. But for his final journey, we all came along 2020-02-09T05:00:00Z The similarities do, however, bear some obvious endpoints. Bridging the Racial Divide in a Middle School Friendship 2018-01-15T05:00:00Z After that, after finally unveiling himself as the walking embodiment of Neil Strauss’s The Game taken to its logical endpoint, the gloves were off for good. So long, Dennis Reynolds – you might just be TV's greatest monster 2017-11-23T05:00:00Z And there are, unexpectedly, even surprises in store on a journey whose endpoint seems preordained. Review: Women’s Hard Choices, Cutting Deep at Williamstown Festival 2016-08-18T04:00:00Z She doesn’t arrive at a totalizing, liberated endpoint. How Much Power Do Women Want? A Novel Circles the Question 2020-01-07T05:00:00Z This highlights a growing problem, however: As the family’s tribulations proceed with no discernible arc or endpoint, the hovering question of who will die next provides the only real tension. The Best of New Sci-Fi and Fantasy, From an Intergalactic Love Story to New York City Under Water 2017-03-21T04:00:00Z As we neared the endpoint of the work, though, I was beginning to fall apart a little. My tantric “awakening” turned me off sex 2013-03-17T01:00:00Z “At last,” he writes, “we arrive at the inevitable endpoint of the monotheistic experiment … God is not the creator of everything that exists. God is everything that exists.” Reza Aslan’s ‘God: A Human History’ 2017-12-19T05:00:00Z Its endpoint: a daybed for people to reflect on. Essential Arts & Culture: Kusama-palooza, Getty Center's birthday, censored Hollywood public art 2017-10-20T04:00:00Z The trailer suggests that the film’s focus is Dunham, or perhaps that “Eloise” was a stepping stone in an artistic journey whose endpoint was “Girls,” but this, thankfully, turns out not to be the case. The Girl with the Eloise Tattoo 2015-03-23T04:00:00Z A marriage is often the endpoint of a comedy. Love May Be Time’s Fool in Fates and Furies 0002-11-29T05:00:00Z But that not knowing, pausing the drive for resolution to explore one’s messy present, feels like a more revelatory endpoint in itself. Why Mrs Fletcher is the most underrated show on TV right now 2019-11-26T05:00:00Z “The influencer industry is simply the logical endpoint of American individualism, which leaves all of us jostling for identity and attention but never getting enough,” Rebecca Jennings wrote recently in Vox. Young Creators Are Burning Out and Breaking Down 2021-06-08T04:00:00Z Perhaps it’s the only plausible endpoint for this album, poised between music and entropy. Radiohead’s Thom Yorke Releases a Surprise Album 2014-09-28T04:00:00Z For years, Lykke Li viewed Los Angeles as a happy endpoint: the edge-of-the-continent spot where this Swedish singer regularly wrapped tours after months spent on the road. L.A.'s 'positivity' allows Lykke Li to unleash her dark side 2014-09-23T04:00:00Z Originally, Petit had hoped to complete a walk across the National Mall, with the Smithsonian Castle as one of its endpoints. At 73, ‘Man on Wire’ Philippe Petit still dances high above the void 2023-03-24T04:00:00Z The classic tour begins at the 50-acre Boston Common, the nation’s oldest public park and endpoint of Frederick Law Olmsted’s green-space network known as the Emerald Necklace. 36 Hours in Boston 2015-09-16T04:00:00Z This is the biggest news to hit the long-running reality franchise in years, and would seem to represent a symbolic endpoint for a show that’s long celebrated its stars’ over-the-top lifestyles. Why Teresa and Joe Giudice Ending Up in Prison Makes Perfect Sense 2014-10-02T04:00:00Z But the drug failed to show a benefit on the more rigorous overall survival endpoint, which measures how long patients lived, irrespective of tumor growth. How Big Pharma Undermined Medical Innovation for Financial Gain 2012-02-16T00:22:16Z Plus, this is a tale that would seem to have a definitive endpoint, once the bombs level Hiroshima and Nagasaki. 'Manhattan' traces a culture of secrecy, nuclear anxiety 2014-07-25T04:00:00Z President Biden said on Wednesday that the endpoint of the Israel-Hamas conflict has to be a Palestinian state that is “real,” existing alongside an Israeli one. Biden Says a ‘Real’ Palestinian State Must Come After War 2023-11-15T05:00:00Z They used current data on Venus' atmosphere as the endpoint for their models and started by assuming Venus has had a stagnant lid through its entire existence. Venus had Earth-like plate tectonics billions of years ago, study suggests 2023-10-26T04:00:00Z We also mentioned that "aha" experiences provide a sense of clarity or understanding that works as an endpoint in one's information search. What if they're not crazy? Belief in conspiracy theories may be normal 2023-10-21T04:00:00Z Liquid biopsies may help determine which patients are benefiting from available immunotherapies and could be a new endpoint for clinical trials testing these treatments. Capturing immunotherapy response in a blood drop 2023-10-09T04:00:00Z After the story’s original endpoint, Robert comes lurking outside Margot’s workplace. How the viral story 'Cat Person' became a movie that goes off the rails — in a good way 2023-10-05T04:00:00Z The soaring “A Sky Full of Stars” would have been fitting endpoint to the show, which was the final concert of the season at Lumen Field. Coldplay shows two decades of evolution at sold-out Seattle concert 2023-09-21T04:00:00Z Each book is a journey, the endpoint of which isn’t clear until she writes her way there. J.A. Jance on ‘Blessing of the Lost Girls’ and how she writes her bestsellers 2023-09-19T04:00:00Z Eventually, the endpoint is this outcome, which is more sustainable and good PR, too: No more disposables at Starbucks. Starbucks is overhauling its iconic cup to save the planet 2023-09-15T04:00:00Z Dr. Carrillo doesn't see it that way at all, noting that the drugs have met endpoints established years earlier in the process through negotiation between the FDA and the drug companies. Navigating new Alzheimer's drugs can be confusing and expensive. So do they really help patients? 2023-09-13T04:00:00Z Highways paralleling the river as it nears its endpoint at the Gulf pass farmland and fishing camps, shrimp boats, offshore oil rig supply vessels and industrial storage yards. A billion-dollar coastal project begins in Louisiana. Will it work as sea levels rise? 2023-08-09T04:00:00Z “Once you introduce content-based criminal prosecutions based on what somebody is thinking, then there really is no logical endpoint,” he said. November trial set for British man accused of ‘thought crime’ in silent prayer 2023-08-09T04:00:00Z "There is no clear endpoint. While that remains the case, this is going to be a question mark hanging over Israel's economy." Analysis: Israel's judicial reform turmoil threatens economic growth, investment 2023-07-30T04:00:00Z "DDOS to critical endpoints are never random. One needs to know a lot of information to know exactly where to hit, thus bringing a lot of systems to a halt," he said. Kenya cyber-attack: Why is eCitizen down? 2023-07-28T04:00:00Z Yellow-clad fare ambassadors, and staff at the Northgate and Angle Lake endpoint stations, will be deployed to help visitors navigate and buy tickets. Getting around Seattle during All-Star Week: bus, train, car, boat and more 2023-07-05T04:00:00Z Lagarde said the endpoint "is something we will know when we get there" because of how inflation is behaving. Central banks, waiting for relief on inflation, lean towards higher rates 2023-06-16T04:00:00Z Current humanity need not be the endpoint of evolution. AI and the threat of "human extinction": What are the tech-bros worried about? It's not you and me 2023-06-11T04:00:00Z "I think omicron represents the endpoint of the evolution of the virus for its fitness," he said, referring to the virus's ability to transmit and evolve. Is the COVID-19 vaccine ready to move on from the original strain? 2023-06-04T04:00:00Z Or they might require developers to stage head-to-head clinical trials that use reduction in mild COVID-19 disease as the endpoint. Companies won’t share COVID-19 shots, stalling future vaccine research 2023-05-30T04:00:00Z Another example is endpoints, like the antivirus program on your laptop – or malware detection software that runs on networks. Insider Q&A: Artificial intelligence and cybersecurity in military tech 2023-05-29T04:00:00Z Large clinical trials testing cancer therapies frequently alter their primary endpoint—the key health outcomes being measured—midstream, a study reports. News at a glance: China’s ethics oversight, ARPA-H’s new science, and $210 million for protein research 2023-05-24T04:00:00Z In a statement on Wednesday, the partners said that the Phase II dose-finding trial met its primary endpoint of weight loss, the Danish company added. Zealand, Boehringer's drug meets main weight-loss goal in mid-stage trial 2023-05-10T04:00:00Z The statue is in a grotto on the property near a lake, an endpoint for the Croome River, which winds through the grounds. Statue Is Defaced in England After Children Were Given Crayons 2023-04-24T04:00:00Z A comparison such as that is often the endpoint of confirmation bias. The NFL’s riskiest behavior: ‘Nexting’ while drafting 2023-04-21T04:00:00Z On maps, rivers are typically depicted as blue lines — with a starting point, usually near a mountain where rainwater collects; and an endpoint, usually in a lake or ocean. There's a river in Pennsylvania whose endpoint is unknown — and it's not the only "lost" river 2023-04-22T04:00:00Z The practice has raised concerns that researchers rework the endpoints to cast the trial results in a more positive light. News at a glance: China’s ethics oversight, ARPA-H’s new science, and $210 million for protein research 2023-05-24T04:00:00Z Ms. Easterly said the cash and authority Congress has already granted to her agency has been used to implement endpoint detection and response capabilities across federal networks. Federal cyber agency’s leader supports banning TikTok, frets China using it to influence elections 2023-03-28T04:00:00Z It’s true that the crash in the bank’s fortunes developed after Dec. 31, the endpoint of KPMG’s audit. Column: As Silicon Valley Bank's red flags were flying, the Fed was AWOL 2023-03-13T04:00:00Z That may change now, with some analysts suggesting it could tilt the Fed toward a lower endpoint in its rate-hiking cycle. SVB collapse to test Fed's faith in a strong, low-risk financial system 2023-03-12T05:00:00Z One of the biggest triggers employees cited was a lack of “endpoint notification”—a heads up when an animal they were looking after was about to be euthanized. Suffering in silence: Caring for research animals can take a severe mental toll 2023-03-09T05:00:00Z Those will show how high they expect interest rates to move in 2023 — illustrating whether they think rate moves will stop after May, the endpoint implied by their latest projections. Why the Federal Reserve Won’t Commit 2023-03-07T05:00:00Z “I think the primary endpoint was clearly met here,” said Dr. Daniel Feikin, a respiratory disease consultant who voted in favor of the vaccine. FDA panel narrowly backs Pfizer RSV vaccine for older adults 2023-02-28T05:00:00Z Unfortunately, all three failed to meet the study endpoints. Opinion | The Checkup With Dr. Wen: Key lessons from recent measles and Marburg outbreaks 2023-02-23T05:00:00Z There’s also something of a feint in the film’s title, which suggests a journey, or at least an endpoint. Review | ‘Return to Seoul’: Portrait of a young woman, untethered 2023-02-22T05:00:00Z To tackle the lack of endpoint notification, the program has begun to place heart-shaped stickers or notes on the enclosures of animals slated to be euthanized. Suffering in silence: Caring for research animals can take a severe mental toll 2023-03-09T05:00:00Z Capitol and ended at their usual endpoint on the steps of the Supreme Court anyway. Pro-lifers debate moving DC anti-abortion march to June 2023-02-22T05:00:00Z Some videos’ comments sections descended into political fighting or conspiracy theories, a common endpoint of modern social media debate on Facebook, Twitter and other American social media sites. How the Chinese spy balloon drama played out on Chinese-owned TikTok 2023-02-07T05:00:00Z But putting up people temporarily in hotels or placing them in housing is not an endpoint. Opinion | There’s an unraveling of humanity at D.C.’s McPherson Square 2023-02-03T05:00:00Z “They feel like they’ve caught up, but they don’t know where the endpoint is. So you approach it more gingerly. They feel their way there.” The Fed’s new challenge: Stay on the gas or tap the brakes? 2023-01-22T05:00:00Z But I didn’t see classical training as an endpoint. John Cale at 80, on collaborations old (Leonard Cohen, Lou Reed, David Bowie) and new 2023-01-23T05:00:00Z It is already getting thinner, and the glaciers at its endpoint have lost mass — one of them, the Zachariae Isstrom, has also lost its frozen shelf that once extended over the ocean. Parts of Greenland now hotter than at any time in the past 1,000 years, scientists say 2023-01-18T05:00:00Z “They are the logical endpoint of this culture of challenging the legitimacy of our democratic processes,” he said. New Mexico shootings follow two years of election assaults 2023-01-18T05:00:00Z Now, after a long vacuum, new multilateral groupings are emerging, though analysts say the endpoint is still hard to ascertain. China threat sparks a web of new relationships for U.S. military in region 2023-01-17T05:00:00Z "If the labor market doesn't soon slow markedly, the Fed will need to push policy rates" beyond the 5.00%-5.25% range most officials now see as an endpoint. Fed's 'inclusive' jobs promise hits reality of inflation control 2023-01-06T05:00:00Z There is no endpoint where the party has finally cleansed itself. McCarthy debacle comes with a lesson: There's a downside to being a party of fascist trolls 2023-01-05T05:00:00Z “I’m not sure what their endpoint is,” Mendelson said of Gray’s response. In D.C., simmering concern over a lawmaker’s health bursts into public view 2023-01-01T05:00:00Z Financial planners say the allocations they suggest for client portfolios are the endpoint — not the starting point — of an investment plan. May I Speak to a Human, Please? 2022-12-22T05:00:00Z His sentences often take a circuitous route before reaching an endpoint, sometimes baffling audiences. In Georgia, a Heated Senate Race Stirs Mixed Emotions in Black Voters 2022-12-03T05:00:00Z Along with the aesthetic benefit of a more attractive flora, I now take this as a health maintenance program for my approaching 70s, and no longer do I look for some endpoint. Opinion | How to beat back the brush, wherever you are 2022-12-01T05:00:00Z “Although the drug did not meet its primary endpoint, the trials further illustrate the relationship between removal of beta-amyloid and reduction of clinical decline,” the association said. Experimental Alzheimer’s drug from Roche fails in trials 2022-11-14T05:00:00Z "Quit paying attention to the pace and start paying attention to where the endpoint is going to be. Until we get inflation down, that endpoint is still a ways out there," Waller said. Morning Bid: Reality check 2022-11-14T05:00:00Z As primary season nears its Tuesday endpoint, Democrats are giving the strategy one more try in New Hampshire, in two congressional races. Democrats spend tens of millions amplifying far-right candidates in nine states 2022-09-12T04:00:00Z Instead, we can recognize, as even Marx would have to admit by now, that any seemingly inevitable endpoint of history often proves to be a mere hitching post before the next stage of the journey. Perspective | Why Gorbachev’s death feels like it’s part of an alternate history 2022-09-02T04:00:00Z As a result, this is the first major gathering of cardinals since 2019, a time when the endpoint of Francis’s pontificate seemed a far more distant notion. The world’s cardinals, who will pick the next pope, get to know one another 2022-08-28T04:00:00Z The blast at Abbey Gate, which also took the lives of more than 170 Afghans, served as a tragic endpoint to America’s 20-year war in Afghanistan. Austin, Inhofe mark anniversary of Afghan airport attack that killed 13 U.S. troops 2022-08-26T04:00:00Z The botched mission served as a tragic endpoint to America’s 20-year war in Afghanistan. Pentagon rolls out plan to safeguard civilians on the battlefield 2022-08-25T04:00:00Z PV diagrams clearly illustrate that the work done depends on the path taken and not just the endpoints. College Physics for AP Courses 2015-08-12T00:00:00Z In fact, quite to the contrary, novae originate from white dwarfs, which are actually the endpoint of stellar evolution for low-mass stars. Astronomy 2016-10-13T00:00:00Z It changes continually and develops through time toward an endpoint or goal, a view that philosophers call teleological. Introduction to Philosophy 2022-06-15T00:00:00Z It is incremental, and it can't be the endpoint of sustainability efforts in media arts. How Hollywood hopes to monster waste 2022-08-18T04:00:00Z Indicate inclusive endpoints with a solid circle and exclusive endpoints with an open circle. College Algebra 2021-12-21T00:00:00Z Or, average the upper and lower endpoints of the confidence interval. High School Statistics 2020-03-27T00:00:00Z Iron is, however, the endpoint of this process. Astronomy 2016-10-13T00:00:00Z We write the solution in interval notation being careful to determine whether the endpoints are included. Intermediate Algebra 2020-05-06T00:00:00Z Also, include left endpoint, but not the right endpoint. Introductory Statistics 2013-09-19T00:00:00Z Did you notice how the parenthesis or bracket in the interval notation matches the symbol at the endpoint of the arrow? Elementary Algebra 2020-04-22T00:00:00Z When working out problems that have a uniform distribution, be careful to note if the data are inclusive or exclusive of endpoints. High School Statistics 2020-03-27T00:00:00Z Manhattan Institute senior fellow Christopher Rufo tweeted: “The Minneapolis teachers union has negotiated a contract in which the district will fire white teachers first. This is the inevitable endpoint of ‘equity.’” Minneapolis school district defends deal to lay off White teachers ahead of minority teachers 2022-08-16T04:00:00Z The distance from the center to the endpoints of the minor axis is 2. Intermediate Algebra 2020-05-06T00:00:00Z The smallest and largest data values label the endpoints of the axis. Introductory Statistics 2013-09-19T00:00:00Z Figure 2.11 The notation for inequalities on a number line and in interval notation use similar symbols to express the endpoints of intervals. Elementary Algebra 2020-04-22T00:00:00Z For example, if an interval has three data values in it, the frequency polygon will show a 3 at the upper endpoint of that interval. High School Statistics 2020-03-27T00:00:00Z When you can consistently edit art, where is the endpoint? No song, movie or show can escape the digital age’s revisionist urges 2022-08-12T04:00:00Z The distance from the center to the endpoints of the minor axis is 2. Intermediate Algebra 2020-05-06T00:00:00Z When working out problems that have a uniform distribution, be careful to note if the data is inclusive or exclusive of endpoints. Introductory Statistics 2013-09-19T00:00:00Z Out in Ballard, a Salmon Bay tunnel now appears more feasible than a bridge, though debates have rekindled over where to place the line’s northwestern endpoint. Sound Transit 3: Progress in West Seattle, paralysis in Chinatown International District 2022-08-12T04:00:00Z Also, include the left endpoint but not the right endpoint. High School Statistics 2020-03-27T00:00:00Z The endpoints of the segment are called the initial point and the terminal point of the vector. Calculus, Volume 3 2016-03-30T00:00:00Z Find the endpoints of the minor axis Step 5. Intermediate Algebra 2020-05-06T00:00:00Z Using the class listing of confidence intervals, count how many of them contain the population mean μ; i.e., for how many intervals does the value of μ lie between the endpoints of the confidence interval? Introductory Statistics 2013-09-19T00:00:00Z Each of these integrals has an infinite discontinuity either at an endpoint or at an interior point of the interval. Calculus, Vol 2 2016-03-30T00:00:00Z The numbers 1 and 5 are called the endpoints of this set. Calculus, Volume 1 2016-03-30T00:00:00Z In other words, the integral of a “derivative” can be calculated by evaluating an “antiderivative” at the endpoints of the curve and subtracting, just as for single-variable integrals. Calculus, Volume 3 2016-03-30T00:00:00Z The notation for inequalities on a number line and in interval notation use the same symbols to express the endpoints of intervals. Intermediate Algebra 2020-05-06T00:00:00Z OR, average the upper and lower endpoints of the confidence interval. Introductory Statistics 2013-09-19T00:00:00Z Integrals of functions over an interval for which the function has a discontinuity at an endpoint may be defined in terms of limits. Calculus, Vol 2 2016-03-30T00:00:00Z We can use similar notation if we want to include one of the endpoints, but not the other. Calculus, Volume 1 2016-03-30T00:00:00Z As long as we have a potential function, calculating the line integral is only a matter of evaluating the potential function at the endpoints and subtracting. Calculus, Volume 3 2016-03-30T00:00:00Z Plot the endpoints and the midpoint on a rectangular coordinate system. Intermediate Algebra 2020-05-06T00:00:00Z All heights fall between the endpoints of an interval and not at the endpoints. Introductory Statistics 2013-09-19T00:00:00Z Is the area under the curve between the left and right endpoint sums? Calculus, Vol 2 2016-03-30T00:00:00Z It is continuous over a closed interval if it is continuous at every point in its interior and is continuous at its endpoints. Calculus, Volume 1 2016-03-30T00:00:00Z The circle on the integral symbol denotes that C is “circular” in that it has no endpoints. Calculus, Volume 3 2016-03-30T00:00:00Z Plot the endpoints and the midpoint on a rectangular coordinate system. Intermediate Algebra 2020-05-06T00:00:00Z The path to those decisions is too straight and too simple, but to Atkinson and Pink’s credit, the endpoint is never obvious. Review: The doc days of summer feature 'Aftershock,' GWAR, Don McLean and Nolan Ryan 2022-07-22T04:00:00Z The behavior at the endpoints depends on r. Calculus, Vol 2 2016-03-30T00:00:00Z As shown in Figure 4.13, one or both of these absolute extrema could occur at an endpoint. Calculus, Volume 1 2016-03-30T00:00:00Z If the linear mass density at point P is directly proportional to its distance from the line through the endpoints, find the mass of the wire. Calculus, Volume 3 2016-03-30T00:00:00Z For an inequality in one variable, the endpoint is shown with a parenthesis or a bracket depending on whether or not a is included in the solution: Intermediate Algebra 2020-05-06T00:00:00Z Find the distance between the two endpoints using the distance formula. Algebra and Trigonometry 2015-02-13T00:00:00Z Note that although Term-by-Term Differentiation and Integration for Power Series guarantees the same radius of convergence when a power series is differentiated or integrated term-by-term, it says nothing about what happens at the endpoints. Calculus, Vol 2 2016-03-30T00:00:00Z If an absolute extremum does not occur at an endpoint, however, it must occur at an interior point, in which case the absolute extremum is a local extremum. Calculus, Volume 1 2016-03-30T00:00:00Z Security lines with unclear endpoints would snake into a new course at the request of airport workers. Turbulence on the Ground at Toronto’s Pearson Airport 2022-07-16T04:00:00Z Since the inequality is strictly less than, the endpoints ar e not included. Intermediate Algebra 2020-05-06T00:00:00Z Highly applicable in calculus, it is a system of parentheses and brackets that indicate what numbers are included in a set and whether the endpoints are included as well. Algebra and Trigonometry 2015-02-13T00:00:00Z Determine whether the resulting series converges at the endpoints. Calculus, Vol 2 2016-03-30T00:00:00Z Figure 4.20 This function has an absolute maximum at an endpoint of the interval. Calculus, Volume 1 2016-03-30T00:00:00Z For those who have lived through bouts of high inflation, projecting an endpoint is fraught with risk and uncertainty. Veterans of Carter-Era Inflation Warn That Biden Has Few Tools to Tame Prices 2022-07-05T04:00:00Z For example, if you have the endpoints of the diameter of a circle, you may want to find the center of the circle which is the midpoint of the diameter. Intermediate Algebra 2020-05-06T00:00:00Z An average rate of change can also be computed by determining the function values at the endpoints of an interval described by a formula. Algebra and Trigonometry 2015-02-13T00:00:00Z However, checking the endpoints and using the alternating series test, we find that the series converges at x = 1 and x = −1. Calculus, Vol 2 2016-03-30T00:00:00Z Therefore, the absolute maximum does not occur at either endpoint. Calculus, Volume 1 2016-03-30T00:00:00Z But now, any parent — and kid — who has been waiting for the vaccines can finally see the endpoint. Relief for Parents 2022-06-17T04:00:00Z To find the midpoint of a line segment, we find the average of the x-coordinates and the average of the y-coordinates of the endpoints. Intermediate Algebra 2020-05-06T00:00:00Z For the following exercises, the vertex and endpoints of the latus rectum of a parabola are given. Algebra and Trigonometry 2015-02-13T00:00:00Z Testing the endpoints by using the divergence test, we find that the series diverges at both endpoints x = ±1. Calculus, Vol 2 2016-03-30T00:00:00Z These extreme values occur either at endpoints or critical points. Calculus, Volume 1 2016-03-30T00:00:00Z It’s true that early June is the time of year often held up for months as the potential endpoint for Virginia high school soccer. Boys’ soccer final Top 10: Langley reigns after Class 6 title 2022-06-13T04:00:00Z Plot the endpoints and the midpoint on a rectangular coordinate system. Intermediate Algebra 2020-05-06T00:00:00Z The first point is called the endpoint of the ray. Algebra and Trigonometry 2015-02-13T00:00:00Z In the case of a line segment, arc length is the same as the distance between the endpoints. Calculus, Vol 2 2016-03-30T00:00:00Z Why do you need to check the endpoints for optimization problems? Calculus, Volume 1 2016-03-30T00:00:00Z “These are different populations. The studies were done at different times. The results are reported in different manners, with different endpoints,” said Dr. Jesse L. Goodman, a former chief scientist for the F.D.A. F.D.A. advisers will debate the long-awaited Covid vaccines for young children. 2022-06-15T04:00:00Z Intermediate endpoints could suffice, he says, and Exact Sciences, the company that owns the test he worked on, is discussing proper test design with the F.D.A. Blood Tests That Detect Cancers Create Risks for Those Who Use Them 2022-06-10T04:00:00Z We can refer to a specific ray by stating its endpoint and any other point on it. Algebra and Trigonometry 2015-02-13T00:00:00Z It is possible that the differentiated and integrated power series have different behavior at the endpoints than does the original series. Calculus, Vol 2 2016-03-30T00:00:00Z Each extremum occurs at a critical point or an endpoint. Calculus, Volume 1 2016-03-30T00:00:00Z That has brought to the foreground questions about Francis’s future — whether his pontificate is nearing its endpoint, and whether he might consider stepping down. Is Pope Francis nearing the end of his pontificate? 2022-06-07T04:00:00Z The new integration system is designed to make the Chrome browser and Chrome OS devices easier for IT departments to implement with existing security, endpoint, and authentication solutions as well as bother management solutions. Google opens up Chrome and Chrome OS to enterprise security, control integrations 2022-05-26T04:00:00Z The endpoint is called the vertex of the angle, and the two rays are the sides of the angle. Algebra and Trigonometry 2015-02-13T00:00:00Z Term-by-Term Differentiation and Integration for Power Series does not guarantee anything about the behavior of this series at the endpoints. Calculus, Vol 2 2016-03-30T00:00:00Z We then form six rectangles by drawing vertical lines perpendicular to xi − 1, the left endpoint of each subinterval. Calculus, Volume 1 2016-03-30T00:00:00Z But whether the endpoint comes in a matter of months or a couple of years is anybody’s guess, and this pontificate has been typified by its surprises. Is Pope Francis nearing the end of his pontificate? 2022-06-07T04:00:00Z The companies said that final data on efficacy, a secondary endpoint for the clinical trial, would be shared “once available.” Pfizer Says 3 Vaccine Doses Produce Strong Response in Young Children 2022-05-23T04:00:00Z The transverse axis is a line segment that passes through the center of the hyperbola and has vertices as its endpoints. Algebra and Trigonometry 2015-02-13T00:00:00Z Term-by-Term Differentiation and Integration for Power Series does not guarantee anything about the behavior of this power series at the endpoints. Calculus, Vol 2 2016-03-30T00:00:00Z When the left endpoints are used to calculate height, we have a left-endpoint approximation. Calculus, Volume 1 2016-03-30T00:00:00Z But the two-dose trial failed to meet its primary endpoint after results for children ages 2 to 4 showed a weaker immune response than in adults. Pfizer/BioNTech say 3 COVID shots elicit good response in children under 5 2022-05-23T04:00:00Z Their pain has meaning, and it has an endpoint. One-fifth of American adults live with chronic pain. Why aren't we talking about it more? 2022-05-04T04:00:00Z The conjugate axis is perpendicular to the transverse axis and has the co-vertices as its endpoints. Algebra and Trigonometry 2015-02-13T00:00:00Z However, checking the endpoints, we find that at x = 1 the series is the alternating harmonic series, which converges. Calculus, Vol 2 2016-03-30T00:00:00Z Express the following endpoint sums in sigma notation but do not evaluate them. Calculus, Volume 1 2016-03-30T00:00:00Z According to OpenText, the companies are using patented technology in their anti-malware applications, specifically in the endpoint security systems that protect specific devices on a network. A series of patent lawsuits is challenging the history of malware detection 2022-04-12T04:00:00Z “We do not know the endpoints of where either of those other two are going, either in capability or capacity,” he said. What Russia’s nuclear escalation means for Washington, with world’s third-largest atomic arsenal 2022-03-12T05:00:00Z If we sketch lines tangent to the parabola at the endpoints of the latus rectum, these lines intersect on the axis of symmetry, as shown in Figure 6. Algebra and Trigonometry 2015-02-13T00:00:00Z Again, Term-by-Term Differentiation and Integration for Power Series does not guarantee anything about the convergence of this series at the endpoints. Calculus, Vol 2 2016-03-30T00:00:00Z In the following exercises, use a calculator or a computer program to evaluate the endpoint sums RN and LN for N = 1,10,100. Calculus, Volume 1 2016-03-30T00:00:00Z Instead of matching file data to a library of known viruses, modern endpoint security looks at actions performed within a computer system. A series of patent lawsuits is challenging the history of malware detection 2022-04-12T04:00:00Z The program allows companies to use what are called “surrogate endpoints” — certain signs in clinical trials that show a medicine might be beneficial for patients. The FDA is approving more drugs that haven’t been shown to work. Are patients being harmed? 2022-03-03T05:00:00Z “For some people, this is a steppingstone toward a more positive body image, and for others, it may be the endpoint.” You don’t have to love or hate your body. Here’s how to adopt ‘body neutrality.’ 2022-02-25T05:00:00Z With a final chocolate chip cookie tucked into a side pocket, I led the way along the easygoing, eight-mile romp toward our endpoint among the trails of the Rikert Nordic Center. Three days along North America’s longest backcountry ski trail 2022-02-18T05:00:00Z It almost seems too simple that the area of an entire curved region can be calculated by just evaluating an antiderivative at the first and last endpoints of an interval. Calculus, Volume 1 2016-03-30T00:00:00Z It’s a real shift in the way companies approach endpoint security. A series of patent lawsuits is challenging the history of malware detection 2022-04-12T04:00:00Z Authorizing vaccines without meeting the endpoint for effectiveness could have worsened vaccine hesitancy. Opinion | Parents of little kids might be disappointed, but the FDA was right to delay vaccine authorization 2022-02-15T05:00:00Z Understanding it is like trying to truly know another person — there is no endpoint, no takeaway, just a lifetime of learning. Perspective | For this Surrealist art couple, love was an alien landscape 2022-02-12T05:00:00Z That endpoint, known as progression free survival, Dr. Pazdur said at the meeting, is out of date for such studies. F.D.A. Panel Rejects Lilly’s Cancer Drug Tested Only in China 2022-02-10T05:00:00Z Calculate the right endpoint estimate R50 and solve for the exact area. Calculus, Volume 1 2016-03-30T00:00:00Z “These lawsuits allege that defendants infringe and unlawfully compete against aspects of the OpenText family of companies’ endpoint security products and platforms. A series of patent lawsuits is challenging the history of malware detection 2022-04-12T04:00:00Z Others offer no reasonable endpoint for restrictions and make continued masking a symbol of their belief in science. Opinion | In this next phase of the pandemic, beware of the extremes 2022-02-08T05:00:00Z An important aspect of the “integration” phase is that it’s not a fixed endpoint. What’s up with white women? Seattle authors wrote a book about that 2022-02-07T05:00:00Z Instead, the appropriate endpoint, he suggested, is what matters to patients most — how long will they live. F.D.A. Panel Rejects Lilly’s Cancer Drug Tested Only in China 2022-02-10T05:00:00Z In my naiveté, I thought that the moment he pulled her onto his surfboard was the endpoint of the drama. Australia revisited - a country changed by Covid 2022-02-03T05:00:00Z Engagement has not meant abandonment of principle, even if its endpoint is unclear. Emmanuel Macron Walks a Fine Line on Ukraine 2022-01-29T05:00:00Z Such training focused on helping clients seek “closure,” an endpoint to grief. What if There’s No Such Thing as Closure? 2021-12-15T05:00:00Z That process relies on a “surrogate endpoint”—here, beta amyloid reduction—rather than a demonstration of clinical benefit. Science’s 2021 Breakthrough of the Year: AI brings protein structures to all 2021-12-15T05:00:00Z I don’t think that that represents the endpoint for the evolution of personal technology, but rather a way station along the road. The metaverse is already here — and it’s full of Pokemon, Niantic CEO John Hanke explains 2021-12-14T05:00:00Z Two wildfires ignited in the foothills of the Colorado Rockies last weekend, pushing residents out of their homes and stretching the state’s fire season past its traditional endpoint. December Fires Raise Concerns Over Remarkable Colorado Drought 2021-12-10T05:00:00Z After walking about nine miles, the group reached their endpoint at a bridge. In Bakersfield, many push for bringing back the flow of the long-dry Kern River 2021-12-09T05:00:00Z Inspired in part by the queries, “The Myth of Closure” takes a sweeping look at racial unrest and the pandemic while refuting the idea that grief has a prescribed endpoint. What if There’s No Such Thing as Closure? 2021-12-15T05:00:00Z The group's poor evidence rating was largely rooted in Biogen's controversial use of "surrogate endpoints," proxy measures that are assumed to correlate with actual clinical endpoints. This one drug threatens to tank Medicare's entire prescription drug model 2021-12-04T05:00:00Z But the lesson of the Delta Works was that progress is not an endpoint. What Does It Mean to Save a Neighborhood? 2021-12-02T05:00:00Z The endpoints of cardiovascular disease are exceptionally well characterized. How a Child’s Heart Health Could Be Decided before Birth 2021-11-30T05:00:00Z It is important to underscore that for all coronavirus vaccine trials, symptomatic infection has been the primary endpoint, and has tracked well with hospitalizations and deaths. Opinion | The CDC got it wrong. It should have urged all adults to get covid-19 booster shots. 2021-11-24T05:00:00Z It also illustrates how violence is the logical endpoint of the right-wing obsession with trolling liberals. The line between right-wing trolling and violence is collapsing 2021-11-22T05:00:00Z Nearly two-thirds had received money through foundations or other philanthropy, according to an analysis released by the center, but such funding often has an endpoint. At this L.A. County health center, a lawyer is just what the doctor ordered 2021-11-15T05:00:00Z There’s also the question of how exporting data works if a company wants to leave iCloud, endpoint security management, and the other issues that can crop up later. Apple’s Business Essentials subscriptions support small businesses that only use Apple 2021-11-14T05:00:00Z But the paths that lead to that endpoint are much less well understood. How a Child’s Heart Health Could Be Decided before Birth 2021-11-30T05:00:00Z Couples on the ropes work through marital problems as they make their way to the endpoint at the Cathedral of Santiago de Compostela. On Spain’s Camino de Santiago, Even Óscar the Donkey Is a Pilgrim 2021-11-06T04:00:00Z Since treatment completion is directly linked to outcomes, this was felt to be an adequate endpoint. Perspective | Tackling racial disparities in cancer care by creating new ways for institutions to operate 2021-10-22T04:00:00Z For Brown, this return to theater is also an endpoint. Making Waves Fall Arts Festival showcases Seattle artists’ experimental and developmental work 2021-10-25T04:00:00Z In actuality, these laws are not only racist in intent but also meant to enable permanent minority rule for the Republican Party, the endpoint of which is a form of authoritarianism. How higher education can win the war against neoliberalism and white supremacy 2021-10-24T04:00:00Z The difficulty, he says, is that there are few studies that directly connect childhood risk factors and the hard adult endpoints of cardiovascular disease—death, for example. How a Child’s Heart Health Could Be Decided before Birth 2021-11-30T05:00:00Z Seeing photographs can be the passive endpoint of the experience, rather than a spur to action. Review: A remarkable ode to union workers in photographer LaToya Ruby Frazier's 'Last Cruze' 2021-10-18T04:00:00Z Is there any hope for creating monuments that will outlast this terrestrial endpoint? Looking for Interstellar Monuments 2021-09-11T04:00:00Z “We don’t have the luxury of waiting three to five years for whatever that magical endpoint might be.” Should the FDA move faster on COVID-19 vaccines for young children? 2021-09-11T04:00:00Z Many of the panels’ questions involve why the agency granted the drug accelerated approval, which is based on a “surrogate endpoint” thought to predict a clinical benefit. House committees step up investigation into FDA approval of controversial Alzheimer’s drug 2021-09-02T04:00:00Z Only recently have some studies begun using more nuanced endpoints measuring changes in a person's quality of life, such as their ability to stand up from a seated position or walk a certain distance. Recovery from an ICU stay is tough. Could more protein help? 2021-08-29T04:00:00Z Our engagements since Sept. 11, 2001, quickly bled beyond America’s immediate incursion in Afghanistan, and they remain without any endpoint even with troops gone from the first place they set foot. Perspective | Biden pulled troops out of Afghanistan. He didn’t end the ‘forever war.’ 2021-08-17T04:00:00Z And there's no evidence that anyone "peeked" at the results before changing the endpoints. Debate erupts (again) over women’s libido drugs 2021-08-20T04:00:00Z And these trials should examine actual outcomes such as hospitalization — not “surrogate” endpoints such as antibody levels. Opinion | Why the Biden administration’s recommendation on booster shots is a mistake 2021-08-18T04:00:00Z In Aduhelm’s case, the endpoint is the drug’s effectiveness at removing sticky clumps of a brain protein known as beta amyloid. House committees step up investigation into FDA approval of controversial Alzheimer’s drug 2021-09-02T04:00:00Z The 2024 Paris Summer Games are less of a dream and more another endpoint. Meet Alabama runner and 2024 Olympic hopeful Chanice Spicer 2021-08-07T04:00:00Z Washington Pass Overlook is at the road’s highest point, offering a 400-foot-long paved trail to an endpoint view of surrounding granite spires and peaks. North Cascades Highway: Explore a stretch of Washington’s newest Scenic Byway | Provided by Western Washington Toyota Dealers 2021-08-04T04:00:00Z In a way, though, the gruesome endpoints Kean describes — the scrambled brains, the ransacked ships, the deathbeds — are the least interesting part of his story. Tales of scientists gone rogue (or worse) 2021-08-01T04:00:00Z Because I think that, to me, one of the reasons the more partisan journalists are succeeding right now is that they’re constantly telling a narrative and that narrative comes to endpoints. Chuck Todd on why Meet the Press can’t survive on just one platform 2021-07-27T04:00:00Z Instead, it granted “accelerated approval” to the drug based on a “surrogate endpoint” — in this case, the drug’s ability to remove amyloid plaque from the brain. The controversial approval of an Alzheimer’s drug reignites the battle over the underlying cause of the disease 2021-07-05T04:00:00Z She noted that under accelerated approval, officials can approve a drug based on a surrogate endpoint — in this case, a reduction in amyloid — if it is “reasonably likely” to produce a clinical benefit. FDA releases fresh details on internal debate over controversial Alzheimer’s drug 2021-06-22T04:00:00Z Other critics have complained about the FDA’s use of “accelerated approval,” which relies on a “surrogate endpoint” that is thought likely to predict clinical benefit but is not a measure of benefit itself. Furor rages over FDA approval of controversial Alzheimer’s drug 2021-06-17T04:00:00Z Waiting to call an endpoint made sense, she said, as the committee was watching for evidence of a second wave of virus outbreak that might cause the economy to tumble again. The Recession Isn’t Over Till They Say It’s Over. (But Who Are They?) 2021-06-14T04:00:00Z O’Connor’s timeline set 2028 as a potential endpoint for racial preferences. Justices consider Harvard case on race in college admissions 2021-06-13T04:00:00Z Today, they often are used for cancer therapies — with tumor shrinkage, for example, serving as a surrogate endpoint. The controversial approval of an Alzheimer’s drug reignites the battle over the underlying cause of the disease 2021-07-05T04:00:00Z Maple, another quarter-mile leg, marks the quadrant’s southern edge; it meets Overlook Trail and kicks north toward the ravine and the endpoint of our walk. Pioneer Park on Mercer Island is a cool, shady retreat for dogs, humans and horses 2021-06-11T04:00:00Z It’s unprecedented, he says, to switch at the last minute from a standard approval process to an “accelerated pathway” that doesn’t require clinical improvements but instead relies on a “surrogate endpoint,” beta amyloid. Alzheimer’s drug approved despite doubts about effectiveness 2021-06-07T04:00:00Z The show’s endpoints were set by events, both political and personal, important to Rasmussen. The 1960s didn’t end until the ’80s. So says this art show about painting in D.C. 2021-06-02T04:00:00Z It’s the endpoint of this route, one of 42 testaments to Japanese American art, culture, family, food and resilience. Get a history refresher on this walking tour of Seattle’s Japanese American Remembrance Trail 2021-05-14T04:00:00Z “Healing is a journey not an endpoint,” another student wrote. Editorial Roundup: New England 2021-05-07T04:00:00Z “Regardless of the reason, the endpoint is always the same. It’s children that are being left unprotected from infectious diseases.” Momentum grows for closing gaps in US vaccine requirements 2021-05-01T04:00:00Z Windows will soon only use a single audio endpoint to automatically switch to the correct Bluetooth profile depending on whether you’re listening to music or taking calls. The next big Windows 10 update improves Bluetooth audio with AAC support 2021-04-29T04:00:00Z Among the vaccinated, the rate of severe illness — the endpoint that really matters — is also extremely low. Opinion | The covid-19 vaccines are an extraordinary success story. The media should tell it that way. 2021-04-20T04:00:00Z Green Lake has bathrooms, parking and is worth a spring afternoon itself — it’s the midway point for this route, but it could justifiably be the start or endpoint. Seattle’s spring beauty is on display on this hike from Puget Sound to Lake Washington 2021-04-14T04:00:00Z If North Carolina’s legislation would impose the most wide-ranging burden on trans kids, it’s just the logical endpoint of these other proposals. Opinion | We should celebrate trans kids, not crack down on them 2021-04-12T04:00:00Z That’s where the book winds up — a quick endpoint that doesn’t feel like a finish. A beloved musician's memoir is cause for celebration ... and mourning 2021-04-06T04:00:00Z The next big Windows 10 update will create a single endpoint for Bluetooth audio. The next big Windows 10 update improves Bluetooth audio with AAC support 2021-04-29T04:00:00Z For sports, the endpoint of the study would be an instant test that could be taken on the sideline to validate a trainer’s concussion diagnosis. Concussions can be diagnosed through a saliva test, British researchers find 2021-03-23T04:00:00Z “If a significant number of people do not get vaccinated, that would delay where we would get to that endpoint,” Fauci warned recently. Half of Republican men say they don't want the vaccine. They're mooching off the rest of us 2021-03-21T04:00:00Z “The endpoint now appears in sight and the funds provided by the three bills for mass transit, airlines and airports is enough to see them all through that period.” Transportation gets a big boost in recovery package but still faces an uncertain future 2021-03-11T05:00:00Z The Johnson & Johnson trial endpoint was also somewhat different, including protection against severe illness. Opinion | All of the coronavirus vaccines can save lives. Take whichever you can get. 2021-03-11T05:00:00Z They even could — no doubt would — turn Trump into a martyr for the authoritarian cause, claiming his imprisonment is due to being "canceled," instead of the logical endpoint of a life of crime. Senate Republicans, too weak to convict Trump, should pray New York prosecutors lock him up 2021-02-23T05:00:00Z This hit its logical endpoint in the branded and sloganeered feminism of the last 10 years. The Lockdown Showed How the Economy Exploits Women. She Already Knew. 2021-02-17T05:00:00Z “Indeed, if we can just demonstrate that the virus grows in the nose, that’s really the endpoint we’re looking for,” he said. U.K. gets approval to infect healthy volunteers in world’s first coronavirus ‘challenge trial’ 2021-02-17T05:00:00Z Extending the season beyond May 8 and delaying the playoffs past the current endpoint of July 9 probably wouldn’t work for NBC, the NHL’s TV partner. Elliott: With no bubble, the NHL season is in trouble. But there is a solution 2021-02-10T05:00:00Z A different endpoint, such as asymptomatic illness, hospitalization or death, might have delayed the clinical trials when time was of the essence. Opinion | All of the coronavirus vaccines can save lives. Take whichever you can get. 2021-03-11T05:00:00Z Mr. Biden said he is sticking to his goal but it is “not the endpoint, it’s just the start.” Limited supply of coronavirus vaccine poses problem for Biden’s massive distribution plan 2021-01-26T05:00:00Z “Were the events at the Capitol the apotheosis and tragic endpoint of Trump’s four years, or was it the founding act of a new American political violence spurred by a dangerous energy?” Trump Bequeaths Biden an Upended World 2021-01-19T05:00:00Z “Democracy,” Repucci concluded, “is not an endpoint. It needs to be supported and fostered constantly by its citizens in order to stay strong and not regress.” Editorial Roundup: Excerpts from recent Minnesota editorials 2021-01-12T05:00:00Z “We didn’t say, ‘Here’s an extra endpoint that’s exciting,” says Hill. Debates over dosing plans for authorized COVID-19 vaccine intensify 2021-01-06T05:00:00Z Or maybe studio films have reached an endpoint in storytelling, suggests Kaufman. Storytelling that twists, bends, even confuses. Welcome to this trippy season 2021-01-05T05:00:00Z We are capable of managing this transition, Veronique de Rugy of George Mason said, but the problem is that we are in the middle of that shift, with little visibility into the endpoint: How Capitalism Is Coping in an Era of Populism 2020-12-16T05:00:00Z In an AstraZeneca news release on Wednesday, the company said that “the primary efficacy endpoint based on a pooled analysis showed that the vaccine was 70.4 percent.” U.K. authorizes Oxford-AstraZeneca coronavirus vaccine 2020-12-30T05:00:00Z This is his legacy: he has successfully led a vast number of voters along the path from hatred of government to contempt for rational deliberation to the inevitable endpoint: disdain for the electoral process itself. Biographer Michael D'Antonio on the most "subversive and traitorous federal official" in history 2020-12-30T05:00:00Z The McKinsey analysis notes that the restoration of parts of our social or economic lives, the second endpoint, may arrive sooner than the epidemiological end of the pandemic. Two authorized vaccines – here's what you need to know. 2020-12-20T05:00:00Z Most states managed to hobble along until the summer, a typical endpoint to the fiscal year. In Blue States and Red, Pandemic Upends Public Services and Jobs 2020-12-04T05:00:00Z This means the FDA recognises that the research “demonstrates the drug may have substantial improvement on at least one clinically significant endpoint over available therapy,” and that research and development will be “expedited.” Psilocybin Treatment for Mental Health Gets Legal Framework 2020-12-01T05:00:00Z It needs people with strong critical and abstract reasoning, who see their work in broader terms than endpoints. How Biden's COVID-19 task force is bringing humanity to science 2020-11-14T05:00:00Z The FDA staff said one of the two studies “provides the primary evidence of effectiveness as a robust and exceptionally persuasive study demonstrating a treatment effect on a clinically meaningful endpoint.” Biogen Alzheimer's drug gets U.S. FDA staff's backing ahead approval meeting 2020-11-04T05:00:00Z “It is the endpoint in a supply chain of disinformation — the tip of an iceberg with an amplification ecosystem of right-wing media, influencers and outright conspiracy theorists making up the bulk below.” The unseen machine pushing Trump’s social media megaphone into overdrive 2020-10-30T04:00:00Z But with levels of the virus rising, it will not be a long wait to reach the endpoint of the trials. Unprecedented vaccine trials on track to begin delivering results 2020-10-21T04:00:00Z “No deal or the thin deal on offer are both likely to be unsustainable endpoints,” they say. No-deal Brexit will cost UK more than Covid, report finds 2020-09-23T04:00:00Z As these hopeless timelines collapse, and now as restrictions on our social lives retighten, the dream of a cathartic endpoint is becoming harder to sustain. Coronavirus is here to stay. The sooner we accept that, the better | Samuel Earle 2020-09-21T04:00:00Z “There are a limited number of approaches to vaccination and a similarly limited number of endpoints, but for therapeutics, there is an enormously wide range of targets and goals.” Coronavirus therapeutics 'more complicated' than vaccine, expert says 2020-09-18T04:00:00Z That they have made it to the start of the season is an accomplishment but far from an endpoint. Tracking devices, ‘Ghostbuster packs’ and Plexiglass: How one NFL team fought coronavirus 2020-09-09T04:00:00Z Though the route of Roberto’s group had changed, its endpoint was the same: Twenty miles north of the border, they would near the town of Sells, on the Tohono O’odham reservation. How U.S. Policy Turned the Sonoran Desert Into a Graveyard for Migrants 2020-08-18T04:00:00Z Thus, lymph-node infiltration is not necessarily an endpoint, but rather a stopover on the cells’ journey elsewhere. Cancer cells stock up in lymph vessels to survive 2020-08-18T04:00:00Z Thirty state election offices have already integrated the so-called endpoint detection and response tools, which are routinely used in the private sector but less common at the local level. Federal program offers new cybersecurity tool for elections 2020-08-04T04:00:00Z What better way to demonstrate the logical endpoint of mankind’s rapaciousness than to cast out little reminders of Ahab’s crew spearing and stripping scores of whales for profit and pleasure? Review: A powerful climate novel reminds us that people are animals too 2020-08-03T04:00:00Z “The endpoint of that we saw in Europe 60 years ago, 70 years ago — what happens when those things get unleashed,” Mr. Obama said, according to the notes. Obama Unleashes on Trump Privately as He Raises $24 Million for Biden 2020-07-30T04:00:00Z The study did not find any statistically significant drop in “medically significant” lower respiratory disease in babies whose mothers received the vaccine, the trial’s primary endpoint. Two new medicines may curb serious respiratory disease in infants 2020-07-29T04:00:00Z If you hadn’t earned the ability to walk into an office, drop the songs on their desk, be like, “You’re welcome” and walk back out, there was no endpoint. Alanis Morissette and Liz Phair swap horror stories about men in the '90s 2020-07-29T04:00:00Z “If you don’t have the capacity to search in your endpoint infrastructure for the bad guys and have human cybersecurity experts work on that for you, in the end, compromise will likely be inevitable.” Federal program offers new cybersecurity tool for elections 2020-08-04T04:00:00Z If that’s the case, Election Day will not be the endpoint, even if Trump is defeated. Analysis | Trump turned July Fourth into a partisan event. The damage could be long-lasting. 2020-07-05T04:00:00Z Before the pandemic, I too imagined myself as, at worst, pre-elderly, while assuming there was widespread agreement about the endpoint of plausible youth. Perspective | With the novel coronavirus, suddenly at 60 we’re now ‘old’ 2020-06-26T04:00:00Z It’s really important to set up the trials with endpoints that are meaningful. ‘We’ve got to be able to move more quickly.’ The pandemic reality of COVID-19 clinical trials 2020-06-16T04:00:00Z But “a lot of times we see awareness, and understanding diversity and inclusion, as the endpoint, but really that’s only Step 1.” Around St. Louis, Black Live Matters resonating in ways it didn’t after Ferguson 2020-06-15T04:00:00Z As they made their way to Bailey Gatzert Elementary School, the march endpoint, students weighed in on what needed to change. Inspired by the 1963 Birmingham Children’s Crusade, Seattle Children’s March draws on rich history of youth protest 2020-06-13T04:00:00Z “Is it an infection endpoint, a transmission endpoint, preventing moderate disease, or preventing severe disease?” ‘It’s really complicated.’ United States and others wrestle with putting COVID-19 vaccines to the test 2020-06-12T04:00:00Z The protests aren’t about Floyd’s death, as such, but his death is a reminder that the endpoint of the system is too frequently the death of a black man. When memorializing George Floyd, Trump makes clear he doesn’t understand the protests 2020-05-31T04:00:00Z “And we’re seeing uncertainty everywhere. There’s no road map from the past. There’s never been this level of social upheaval. And there’s no clear endpoint.” If Life Is a Movie, It’s Called ‘Closed Until Further Notice’ 2020-05-19T04:00:00Z They couldn’t keep the trial going past its planned endpoint in hopes of detecting benefits still unseen. Coronavirus discoveries can come along faster with adaptive clinical trials 2020-05-18T04:00:00Z “What are your endpoints going to be?” she said, speaking to Stat News. 20K volunteer for coronvirus exposure in possible 'human challenge trial' 2020-05-14T04:00:00Z A COVID-19 vaccine that fails to prevent infection might still provide great benefit if it reduces symptomatic disease, so Warp Speed and Solidarity both ultimately chose that as the primary endpoint of the trials. ‘It’s really complicated.’ United States and others wrestle with putting COVID-19 vaccines to the test 2020-06-12T04:00:00Z This is the endpoint of the negative scenario: a giant domino effect, leading to the disintegration of the European Union. 'There is a glimmer of hope': economists on coronavirus and capitalism 2020-05-06T04:00:00Z Gilead said a separate trial by the National Institute of Allergy and Infectious Diseases met its goal, or “primary endpoint,” but said it is up to the agency to reveal more. Gilead Sciences reports promising early results in COVID-19 trial using remdesivir 2020-04-29T04:00:00Z The game’s puzzles require you to navigate one of the characters across various platforms to an endpoint. A Fold Apart turns working through anxiety into puzzle solving 2020-04-26T04:00:00Z Europe’s major leagues are still trying to find a way of completing their seasons by extending beyond their usual endpoints around May and June. Concern for players’ mental health with soccer shut down 2020-04-20T04:00:00Z Our points of departure were different, opposite sides of a shared story, yet our paths crossed and we arrive at an endpoint. On the trail of a Nazi war criminal: 'It's my duty as a son to find the good in my father' 2020-04-18T04:00:00Z That term, “developed economy”, sounds like an endpoint, like man standing upright after a series of hunched and hairy iterations. Coronavirus is revealing how broken America’s economy really is 2020-04-06T04:00:00Z And if scientists devise a coronavirus vaccine or treatment, it would provide a clear, obvious endpoint to the panic and fear, a signal that a leader’s powers should be curtailed. Perspective | Dictators are using the coronavirus to strengthen their grip on power 2020-04-02T04:00:00Z Migration isn’t a journey between two endpoints; migration is the point — the animals eat their way along the path, scientists say. Rocky Mountain animals will move as the climate changes. These corridors could give them a safer path. 2020-03-18T04:00:00Z But Voest acknowledges that if overall cancer-survival data are taken as the endpoint, the benefits might not yet be as clear. How cancer genomics is transforming diagnosis and treatment 2020-03-24T04:00:00Z “There is no endpoint in sight, and that’s causing a degree of panic because people are saying, ‘I just need to hold some cash.’ U.S. markets wrap up worst week since the 2008 financial crisis 2020-03-20T04:00:00Z The other key distinction is that unlike war, there is a definitive endpoint, the glimpses of which are slowly becoming apparent. What will the post-coronavirus global economy look like? 2020-03-20T04:00:00Z “It is how we respond to that challenge that’s going to determine what the ultimate endpoint is going to be.” The Coronavirus Show has but one star — and the rest are supporting players 2020-03-16T04:00:00Z The Manchester Arena suicide bombing, an attack lasting only a moment, was the endpoint of a lengthy conspiracy. The road to the Manchester Arena bombing 2020-03-17T04:00:00Z “It is how we respond to that challenge that is going to determine what the ultimate endpoint is going to be.” Trump calls on Americans to cease hoarding food, supplies 2020-03-16T04:00:00Z In the process, gender is revealed as complex, fluid and performative; a beginning, not an endpoint, in determining who we are. ‘A queer person can be anybody’: the African photographers exploring identity 2020-03-15T04:00:00Z She and her partner Joe had to navigate them to the endpoint, about 25 miles across land and water from where they started, she said. Lafayette nurse takes on ‘Naked and Afraid’ for late friend 2020-03-08T05:00:00Z And what is the endpoint of this mentality, when a man believes his status gives him access to women’s bodies? With Harvey Weinstein’s conviction, the old excuses no longer apply | Hadley Freeman 2020-02-25T05:00:00Z This year’s address was the logical endpoint of the long-gathering trend. Opinion | Congress should put an end to the State of the Union. For good. 2020-02-07T05:00:00Z The result could be the start of a prolonged investigation with no clear endpoint, keeping questions about the president’s conduct alive through the election in November. Trump wins acquittal, but Ukraine saga far from over 2020-02-05T05:00:00Z In his playing style, he took Jordan’s legendary competitive nature to its logical endpoint. Say hello to the bad guy: How Kobe Bryant crafted the Mamba mentality 2020-01-29T05:00:00Z A decrease in these markers is the most informative and crucial endpoint parameter for shock-and-kill approaches. Reactivation of latent HIV moves shock-and-kill treatments forward 2020-01-21T05:00:00Z “No one has a solution and an endpoint. We need to get our combat troops out,” Warren said. Democrats clash over positions on war and peace — and gender in politics 2020-01-15T05:00:00Z Donald Trump is the endpoint and the symptom of a social, political and economic system in crisis. Democracy fatigue and how to fight it: Philosopher Henry Giroux on life in the age of Trump 2020-01-07T05:00:00Z Its endpoint is a dystopia of embittered, terrified, suffering communities armed against each other, fighting against a backdrop of ever-increasing immiseration. The only way to fight antisemitism is solidarity and compassion - not division | Joshua Leifer 2019-12-30T05:00:00Z Second, potentially vulnerable Democrats may be breaking in support of impeachment as the process nears its House endpoint, but the party is not completely unanimous on the issue. Impeachment on track to pass thanks to Trump-district Democrats 2019-12-17T05:00:00Z Despite the varied paths leading to epilepsy, all share one endpoint: disruption in electrical missives between neurons, which manifests as seizures. As epilepsy drugs fail nearly one-third of patients, scientists seek root causes of seizures 2019-12-12T05:00:00Z They would be asked where they started and where is the endpoint. Friends spent 79 days cycling across the country 2019-12-10T05:00:00Z And that hardware was tied to software and services like never before — every light bulb the endpoint of a cloud service, every speaker imbued with the voice of the data center’s soul. The 100 gadgets that defined this decade 2019-12-10T05:00:00Z The new netting along the left-field line will extend an additional 85 feet from the previous endpoint and 8 feet from the previous height, making that side about 275 feet long and 22 feet high. Twins to add more safety netting at Target Field 2019-12-05T05:00:00Z I decided that our last game at White Hart Lane should be the endpoint of this project. A fan's-eye view at the football – a photo essay 2019-12-05T05:00:00Z Modi’s decision to revoke the article seemed the logical endpoint of the R.S.S. world view: the Kashmiri deadlock would be broken by overwhelming Hindu power. Blood and Soil in Narendra Modi’s India 2019-12-02T05:00:00Z The endpoint, the saving grace, is endurance, wry humor and a piece of something tucked away from a place once called home. Review: Migrant voices echo with wit, nostalgia 2019-10-26T04:00:00Z Each project feels like a playful take on modernity’s increasingly alienating trends; there’s nothing like seeing the astrology boom, for example, taken to its logical endpoint, which is to say being captured entirely by capitalism. There’s now an app that lets you pick stocks based on your astrological sign 2019-10-22T04:00:00Z The logical endpoint of all this would be the eventual fading-out of the breathing, acting middlemen entirely. Cinema’s digital impostors are coming 2019-10-22T04:00:00Z The film version has an explosive endpoint already set, and the filmmakers build carefully to it. Before HBO’s Watchmen, stream the best Alan Moore adaptation 2019-10-18T04:00:00Z When searching for common ground, I notice that both sides frequently reference China as an undesirable endpoint. 'We are hurtling towards a surveillance state’: the rise of facial recognition technology 2019-10-05T04:00:00Z A curiously detached an philosophical viewpoint on a looming catastrophe which is the logical endpoint of the last 30 plus years of conservative ideology and practice. Opinion | Last Exit From Trumpland 2019-09-27T04:00:00Z So it came as a surprise that Mr. Rouhani imagined meeting Mr. Trump as the logical endpoint of negotiations — assuming the conditions are right. Trump-Rouhani Meeting Was a Near Miss, but Iran Leaves the Door Open 2019-09-26T04:00:00Z Tsing says businesses need to “protect endpoints from being compromised and possibly infecting the rest of your network.” Edward Snowden’s new book 'Permanent Record' touted as bait in malware scam 2019-09-26T04:00:00Z FDA’s regulations allow approval of a drug based only on surrogate endpoints, if it addresses an unmet medical need and the condition is serious. A new sickle cell drug could soon get U.S. approval. But does it work? 2019-09-17T04:00:00Z They vary widely, however, in approach, endpoint, exposure characteristics, and quality. 5G Is Coming. How Worried Should We Be about the Health Risks? 2019-09-16T04:00:00Z The new funds, which double the amount raised to date, will be used to fuel global growth and further innovate its cloud-based endpoint protection platform, Cybereason said. Cyber defense firm Cybereason raises $200 million from Japan's... 2019-08-06T04:00:00Z The trial did not meet a component of the primary endpoint, defined as the pre-specified 15 percent lower bound of the confidence interval between treatment groups. A Possible New Way to Treat Peanut Allergy 2019-06-28T04:00:00Z Use of these endpoints would be a recognition of our published real-world, patient experience data. A Streamlined Pathway to Drug Approval 2019-06-26T04:00:00Z And when it grants approvals based on surrogate endpoints, the agency requires companies to conduct additional trials to prove a drug clinically benefits patients. A new sickle cell drug could soon get U.S. approval. But does it work? 2019-09-17T04:00:00Z The incel phenomenon is a predictable endpoint for a culture that increasingly uses sex as a marker of success, while at the same time losing human connection and substituting the Internet in its stead. Opinion | Men are in trouble. ‘Incels’ are proof. 2019-06-07T04:00:00Z "This is the first randomized trial where breast cancer was an endpoint, and we've been able to show a reduction in deaths," said Dr. Rowan Chlebowski, the study’s author, NBC News reports. New study suggests that certain diets lower risk of death from breast cancer 2019-05-16T04:00:00Z The Labs program and the first API endpoint changes will roll out in the coming weeks. How social networks are recruiting teenage extremists 2019-05-15T04:00:00Z Their survival seems impossible, which may not satisfy viewers who desired a more pronounced endpoint for the cruel, tormented Cersei, to say nothing of some salvation for her fleetingly redeemed brother. ‘Game of Thrones’ Season 8, episode 5: Dany's song of fear and fire unleashes war's horrors 2019-05-13T04:00:00Z But Endgame is meant as a significant endpoint for the Marvel movie universe. Why Avengers: Endgame shouldn’t have a post-credits scene 2019-03-27T04:00:00Z Nazism starkly illustrated the horrors that were a logical endpoint of eugenic privileging of population composition over individual human life. Opinion | Racist terrorists are obsessed with demographics. Let’s not give them talking points. 2019-03-18T04:00:00Z I’d reached the logical endpoint of virtual commerce, the point at which life mattered only in two dimensions. 'I looked like a clown': the truth about shopping on Instagram 2019-03-15T04:00:00Z The highest I saw was 79 wins during the event, hours before the endpoint. A Tetris pro helped me survive Tetris 99’s first big tournament 2019-03-12T04:00:00Z But Montgomery officials are concerned that moving the system opening to 5:30 a.m. would impose too much of a burden on residents who travel from endpoint stations such as Glenmont and Shady Grove. Compromise would close Metro at midnight weekdays, 2 a.m. weekends, but push weekday openings back to 5:30 a.m. 2019-02-21T05:00:00Z “A lot of people want to look way ahead, but there are stages and ways to reduce risk but not get to the endpoint right away.” Stephen Biegun tutored Sarah Palin on foreign policy. Now he’s trying to clinch a North Korea deal for Trump. 2019-02-20T05:00:00Z Oliver seemed momentarily taken aback, before saying the Constitution offers a clear endpoint to the Trump presidency – whether it comes in 2020 or 2024. John Oliver loudly booed during Stephen Colbert interview for suggesting Trump could be re-elected 2019-02-12T05:00:00Z The logical endpoint of excessively avid work, of course, is burnout. Why Are Young People Pretending to Love Work? 2019-01-26T05:00:00Z It includes surrogate endpoints and no placebo, but should satisfy European regulators. A father’s fight to help his sons — and fix clinical trials 2019-01-08T05:00:00Z You don’t necessarily need a full assistant on your dishwasher, but you might want it to do more than just act as an endpoint for receiving commands from your Assistant. This E Ink screen is the first of many new Google Assistant gadgets 2019-01-08T05:00:00Z Homecoming isn’t an endpoint, it’s a beginning, the crest of a new wave of shows that will soon flood TV screens. In the race to turn podcasts into TV shows, the podcasts are winning 2019-01-07T05:00:00Z They also need to evaluate the planned D.C. endpoint. Opinion | Can Amazon move D.C.-area commuting into the 21st century? 2018-12-07T05:00:00Z Two lived healthily for three months — the original designated endpoint of the experiment. Success for pig-to-baboon heart transplants 2018-12-04T05:00:00Z And success of the treatment — the clinical endpoint — was defined in a very narrow way. A father’s fight to help his sons — and fix clinical trials 2019-01-08T05:00:00Z An alternative term — perhaps ‘clinical improvement’ or ‘satisfactory endpoint’ — might help. Statistical pitfalls of personalized medicine 2018-11-26T05:00:00Z Eradication, while presented as an inevitable endpoint in press releases, seemed laughably far away to us on the ground. Three decades later, we’re still grappling with the guinea worm 2018-11-24T05:00:00Z This New York Times investigation is the logical endpoint of corporate feminism. Feminists gave Sheryl Sandberg a free pass. Now they must call her out | Jessa Crispin 2018-11-17T05:00:00Z Then, later on, researchers examined the samples to determine how well the ctDNA data correlated with information from biopsies and scans, as well as with various clinical endpoints, such as remission, relapse and death. Towards the better diagnosis of lymphoma 2018-11-13T05:00:00Z Still, without meeting its endpoint goals, nitisinone was not going to win approval in the United States. A father’s fight to help his sons — and fix clinical trials 2019-01-08T05:00:00Z The Federal Energy Regulatory Commission application says the project would start at the current project’s endpoint in Pittsylvania County, Virginia. Mountain Valley submits application for N Carolina pipeline 2018-11-08T05:00:00Z “It’s not just about trade. It’s geopolitical, military, diplomatic and economic, which is why there’s no real endpoint in sight. In many respects, it’s also an end-of-history-type competition between rival political systems.” Who will win the Trump-China trade war? And at what cost? - Los Angeles Times 2018-10-05T04:00:00Z “I think there is an understanding that we’re approaching the endpoint of these negotiations, and there will need to be some movement on the EU side,” he said. Britain's Brexit proposals imperfect but credible, Raab says 2018-09-19T04:00:00Z So we arrive at the logical endpoint of free market fundamentalism. Ignore Zuckerberg. With skill and imagination we can drive the haters offline | Zoe Williams 2018-07-31T04:00:00Z Rasenberg thinks European regulators will accept it for simple endpoints because it meets validating criteria for so-called quantitative structure-activity relationship models. New digital chemical screening tool could help eliminate animal testing 2018-07-11T04:00:00Z The debate over Exondys 51 centered on the value of a so-called surrogate endpoint, a biological or chemical measure that serves as a proxy for whether the drug actually treats or cures the disease. FDA repays industry by rushing risky drugs to market 2018-07-02T04:00:00Z Focusing on the potential of people with dementia shooting others is a “bloody shirt-waving tactic that’s used to stir emotions to advance support for a particular policy endpoint,” he said. Unlocked and loaded: Families confront dementia and guns 2018-07-01T04:00:00Z The company said that a clinical trial for its treatment of interstitial cystitis and bladder pain syndrome failed to meet its primary endpoint. Concho Resources, CMS Energy climb while Conagra stumbles 2018-06-27T04:00:00Z Leveraging on artificial intelligence, CrowdStrike’s Falcon platform prevents attacks on endpoints - which is a desktop or a server - on or off the network. Cybersecurity firm CrowdStrike raises $200 million 2018-06-19T04:00:00Z “They’re designed to make sure that only the endpoints have access to the communications.” Analysis | The Cybersecurity 202: Trump associates may need a lesson on how to use their encrypted apps 2018-06-18T04:00:00Z The trial also did not include heart failure as a primary endpoint, and alcohol consumption is associated with a higher risk of heart failure, the investigators said. Major Study of Drinking Will Be Shut Down 2018-06-15T04:00:00Z But diversity is a midpoint, not an endpoint. The strange failure of the educated elite 2018-05-29T04:00:00Z Similarly, Trump never seemed to take seriously the reality that Kim was looking not for a quick deal but for a messy multistage process, with denuclearization a distant endpoint. Opinion | Trump may be the worst presidential dealmaker in modern history 2018-05-27T04:00:00Z As Winchester points out, there is an Official History of precision that has a beginning, numerous interim phases and a possible endpoint lurking somewhere in ambiguous subatomic realms. ‘The Perfectionists’: In the world of geniuses, perfection is key to creation 2018-05-20T04:00:00Z Melania may not be reluctant, so much as theatrically embodying a 21st-century cultural endpoint, a wry, impeccably groomed nihilism, ascending each podium like a woman who, sentenced to the guillotine, doesn’t care. Is Melania Trump the most reluctant first lady ever? 2018-05-08T04:00:00Z About a month later, a Trump lawyer pointed to the end of March as an expected endpoint. Another failed prediction from Trump's legal team on the Mueller probe's end 2018-05-03T04:00:00Z I always knew the story had an endpoint. It's handled — 'Scandal' cast and producers pledge 'satisfying' ending as show says goodbye 2018-04-13T04:00:00Z But they consider qualifying for the playoffs to be the start of their journey, not the endpoint. Kings are excited to have earned a postseason berth, but a celebration can wait 2018-04-05T04:00:00Z As of yesterday afternoon, however, the duplicitous campaign reached its endpoint. With Bolton pick, Trump betrays his own vision 2018-03-23T04:00:00Z As a benchmark of clinical success, this “endpoint” is quicker, and cheaper, to prove. FDA wants to help unproductive drugmakers 2018-03-22T04:00:00Z While composting is a better endpoint than the landfill, it’s not the outcome that forestry-focused environmentalists like Paglia are looking for. As coffee cup controversy simmers, Starbucks vows to spend $10M to invent new ones 2018-03-20T04:00:00Z “We will permit an endpoint that shows substantial reductions but does not require the patient to be totally clean at every visit if the measurements are fairly frequent,” a senior F.D.A. official said. F.D.A. to Expand Medication-Assisted Therapy for Opioid Addicts 2018-02-25T05:00:00Z Just as a Google Cast-enabled TV is just an endpoint for any streaming video, perhaps Vaunt is just an endpoint where cloud apps can stream information. Intel is making smart glasses that actually look good 2018-02-05T05:00:00Z This is a long fight and, like it or not, the endpoint is Nov. 6. Opinion | Democrats lost the shutdown before it started 2018-01-24T05:00:00Z Psychology, epidemiology and the clinical sciences are all geared towards producing statistically significant, definitive studies centred on an endpoint that supports a hypothesis. Robust research needs many lines of evidence 2018-01-22T05:00:00Z I want students to see credit hours, classroom spaces and degrees as artificial endpoints that restrict the unbridled pursuit of knowledge. The Soul of My Pedagogy 2018-01-23T05:00:00Z The additional officers are working primarily at the endpoints of a handful of lines, including the E, A and No. 1. As Homeless Take Refuge in Subway, More Officers Are Sent to Help 2018-01-14T05:00:00Z The endpoint of this trend may not be favorable even to the Republican Party and the extremely wealthy individuals who control it and now seem to be its only true constituency. Opinion | The Tax Bill That Inequality Created 2017-12-16T05:00:00Z At peak travel times, boats might run directly from one high-volume stop on a route, say Long Island City, to an endpoint like Pier 11 in Lower Manhattan. New York City’s Ferry Fleet Is Off to a Fast Start 2017-11-29T05:00:00Z It's not clear precisely what the researchers had in mind, because Sarepta's description of this "key secondary efficacy endpoint" on the national clinical trial registry Web site was vague. Is the FDA Withholding Data about a Controversial Drug to Protect Its Manufacturer? 2017-11-29T05:00:00Z This was a Randomized Controlled Trial with hard-outcome endpoints, the “gold standard” of epidemiological proof, and one of the ten most important medical RCTs of the last decade. Nuts May Lower Your Risk for Heart Disease 2017-11-16T05:00:00Z The experts, though, seemed generally impressed by the results—with some reservations about the endpoint—and several were open to treating very young patients. FDA experts offer a unanimous endorsement for pioneering gene therapy for blindness 2017-10-13T04:00:00Z This time, both endpoints were significantly different from placebo, but the FDA was unhappy with the degree of change, and again rejected flibanserin. Sexual arousal: Sex matters : Nature : Nature Research 2017-10-03T04:00:00Z That being said, he wonders about the aims of the protests: “Once you start protesting open-ended societal problems there’s no obvious endpoint.” Right and Left React to the N.F.L. Protests and Trump Statements 2017-09-25T04:00:00Z That strategy currently includes leveraging its processing know-how to deliver serious power to everything from 5G's back-end delivery networks, to endpoint technology that we'll see deployed in smart cities, smart homes and smart vehicles. Intel Plans to Radically Change High-Speed Wireless Internet 2017-09-25T04:00:00Z Many of the trends that led to Trump’s election have been with us for years; he has created a crisis by pushing them to their alarming endpoints. Perspective | How Trump is helping to save our democracy 2017-09-22T04:00:00Z He did not view justice as an endpoint, or a goal with a clear finish line. UW’s Ana Mari Cauce: Together, we must stand against bigotry and work for justice 2017-08-28T04:00:00Z Its first final-stage clinical trial sought an improvement in 'satisfying sexual events', an ill-defined endpoint that was nonetheless achieved. Sexual arousal: Sex matters : Nature : Nature Research 2017-10-03T04:00:00Z Then we have the endpoint: Obi-Wan’s become this crazy hermit that hangs out in the Dune Sea. What would an Obi-Wan Kenobi film mean for the future of the Star Wars franchise? 2017-08-19T04:00:00Z And compromising endpoints – both smartphones and personal computers – is getting easier all the time. End-to-End Encryption Isn’t Enough Security for “Real People” 2017-08-15T04:00:00Z It’s important to keep in mind that the initial discovery of deception is not an endpoint. What We Learned From Watching Kids Figure Out How to Lie 2017-08-05T04:00:00Z Dieckmann tries too hard to force a character sketch into a dramatic shape by giving Darcy’s quest a preset endpoint: the Louisiana office of Walker’s old classmate, who stole his lucrative franchise restaurant idea. A fine Holly Hunter navigates a choppy narrative in Southern drama 'Strange Weather' 2017-07-27T04:00:00Z Its failure to meet “endpoints” for progression-free survival is seen as a major setback. Shares in AstraZeneca dive as key cancer drug trial fails 2017-07-27T04:00:00Z This was supposed to be the week the fight over the Republican health care overhaul reached its endpoint. Who benefits from a delayed vote on Republican health care plan? 2017-07-17T04:00:00Z Why are we most vulnerable at the endpoint? End-to-End Encryption Isn’t Enough Security for “Real People” 2017-08-15T04:00:00Z Uhlén says that the Human Cell Atlas is important and exciting, but adds: “We need to be very clear, what is the endpoint?” How to build a human cell atlas 2017-07-04T04:00:00Z Trump has inherited America's longest conflict with no clear endpoint or a defined strategy for American success, though U.S. troop levels are far lower than they were under Presidents Barack Obama and George W. Bush. The U.S. Is Sending About 4,000 More Troops to Afghanistan 2017-06-15T04:00:00Z Trump has inherited America’s longest conflict with no clear endpoint or a defined strategy for American success, though US troop levels are far lower than they were under presidents Barack Obama and George W Bush. US sending almost 4,000 extra forces to Afghanistan, Trump official says 2017-06-15T04:00:00Z That case, filed more than a year before the case against Boeing, is closer to an endpoint. WTO upholds ruling against Washington’s tax reduction for Boeing 2017-06-09T04:00:00Z Inventing new ways to protect our digital endpoints without reducing their usefulness is very challenging, but some new technologies just over the horizon might help. End-to-End Encryption Isn’t Enough Security for “Real People” 2017-08-15T04:00:00Z When we add the endpoints 0 and 1, the interval becomes compact. What Does Compactness Really Mean? 2017-05-27T04:00:00Z Meanwhile, 53 percent complained about the complexity and number of systems they had to manage, and almost as many said it was hard to monitor all the “endpoints” of the data itself. Inside the Beltway: ‘House of Cards’ confronts ‘age of Trump’ 2017-05-29T04:00:00Z “If Congress has a different way to get to that endpoint, God bless them — that’s great,” Mr. Mulvaney said on Monday as he previewed the plan. Republicans, Pushing Aside Trump’s Budget, Find Few Alternatives 2017-05-23T04:00:00Z The drug, galcanezumab, met its primary endpoint in three phase 3 studies, showing significant reductions in the number of monthly migraine headache days compared with placebo at both studied doses, the Indianapolis... Lilly’s New Migraine Drug Shows Positive Results 2017-05-12T04:00:00Z Computer security experts are excited about the idea that blockchain technology might be able to help us secure our own endpoints. End-to-End Encryption Isn’t Enough Security for “Real People” 2017-08-15T04:00:00Z The high-precision location features may allow train dispatchers to pinpoint the precise endpoints of a train, which could help avoid collisions or improve the efficiency of rail operations. This company wants to build a wireless network for drones, trains and automobiles 2017-05-05T04:00:00Z Throughout, she knew the book’s endpoint, but wasn’t sure how to get there. ‘Girl on the Train’ author Paula Hawkins dives into another thriller 2017-04-27T04:00:00Z Ostrander and Parker say they see this publication as a midpoint, not an endpoint. Where did your dog come from? New tree of breeds may hold the answer 2017-04-25T04:00:00Z Grizzly Steppe is the name given by the US government to efforts by "Russian civilian and military intelligence services to compromise and exploit networks and endpoints associated with the US election". Callisto Group hackers targeted Foreign Office data - BBC News 2017-04-13T04:00:00Z What this means for endpoint security is that computer scientists might be able to create blockchain-based tools to help us verify the origin of our apps. End-to-End Encryption Isn’t Enough Security for “Real People” 2017-08-15T04:00:00Z Cyberbit entered the commercial market by developing detection and response systems to protect "endpoints" such as laptops and mobile devices, where it competes with Carbon Black and FireEye of the United States. Elbit's Cyberbit hones military technology for commercial market 2017-04-13T04:00:00Z Adaptive designs, in contrast, allow researchers to review results before the study’s predetermined endpoint. Congress and FDA nominee heap love on ‘adaptive trials’ 2017-04-07T04:00:00Z The duration of drug treatment was typically 4 weeks before endpoint analysis. Effective combinatorial immunotherapy for castration-resistant prostate cancer : Nature : Nature Research 2017-03-19T04:00:00Z If the US Senate approves his appointment, in the future, more drug approvals might be made on the basis of surrogate endpoints. The FDA chief must not be a proxy for industry 2017-03-16T04:00:00Z To guard against either type of EvilRegime’s trickery, we need to improve our endpoint security game in a few key ways, making sure that: End-to-End Encryption Isn’t Enough Security for “Real People” 2017-08-15T04:00:00Z This is one of the world’s leading providers of endpoint protection. What the CIA thinks of your antivirus program 2017-03-08T05:00:00Z But experts said that rather than defeating the encryption of those applications, the CIA’s methods rely on exploiting vulnerabilities in the devices on which they are installed, a method referred to as “hacking the endpoint.” WikiLeaks says it has obtained trove of CIA hacking tools 2017-03-07T05:00:00Z It’s got to do all its computation at the endpoint and only pass back to the cloud, if it’s connected at all, important bits of curated information. Three VCs on What’s Next in Technology 2017-03-07T05:00:00Z The core technologies of both companies focus on some form of “endpoint” protection designed to automatically deny hackers access. Fairfax City cyber start-up Invincea sells to a British firm for up to $120 million 2017-02-08T05:00:00Z SentinelOne uses machine learning and behavior analysis to provide threat prevention, detection and response for endpoints. Cyber firm SentinelOne raises $70 million bringing total to over $110 million 2017-01-25T05:00:00Z It was so huge that some participants reached the endpoint at Seattle Center before others were even able to leave Judkins Park, where the trek started. Massive crowd in Seattle rallies against Trump 2017-01-21T05:00:00Z On Tuesday morning, that timeline finally reached its endpoint. Former Sounders forward Herculez Gomez retires, will join ESPN as studio analyst 2017-01-17T05:00:00Z They represent the logical endpoint of the Industrial Revolution, when all human labor has been offloaded onto machines. Why Peter Thiel Fears “Star Trek” 2017-01-13T05:00:00Z The liveliest question about Neanderthals was still the first one: Were they our direct ancestors or the endpoint of a separate evolutionary track? Neanderthals Were People, Too 2017-01-11T05:00:00Z Cue a UN summit about cyberwarfare, and the development of some code of conduct, or an anti-cyberwarfare treaty that provides historians with a neat endpoint. We're living through the first world cyberwar – but just haven’t called it that | Martin Belam 2016-12-30T05:00:00Z They have also suggested adopting a more modest endpoint. Cell-based therapy: Cells on trial : Nature : Nature Research 2016-12-20T05:00:00Z The measure also will allow far wider use of simpler goals in medical studies called “surrogate endpoints.” Senate Clears Bill to Ease FDA Drug and Device Approvals 2016-12-07T05:00:00Z But when negotiations neared a critical endpoint, the Taliban were gripped by a vicious power struggle. Ally, Enemy or Both? Saudi Arabia’s Many Roles in Afghanistan 2016-12-06T05:00:00Z Called “surrogate endpoints,” these can involve proving things like changes to biomarkers in a patient’s blood. House Passes Health Bill to Speed Drug Approvals, Boost Biomedical Research 2016-11-30T05:00:00Z The company came under fire over the summer when it changed the endpoint of the trial. A Promising Alzheimer’s Drug Doesn't Work After All 2016-11-23T05:00:00Z The trial's main endpoint was a difficult one: sustained clinical remission after one year, which was defined as no evidence of active disease on endoscopic imaging, and patients able to stop standard medication. Cell-based therapy: Cells on trial : Nature : Nature Research 2016-12-20T05:00:00Z With all of that in mind, the inauguration could be viewed as both a natural and convenient endpoint. Bloomberg to End Its Daily Politics Show 2016-11-17T05:00:00Z Dr. Lauer also was encouraged by the finding that the fourth study, which used imaging, showed the same pattern as the others that used heart attacks and other signs of heart disease as endpoints. Genetic Heart Disease Risk Eased by Healthy Habits, Study Finds 2016-11-13T05:00:00Z “To then drill into secondary endpoints and find superiority — that’s not really fair,” he said. Celebrex Is Found to Be No Riskier for Hearts Than Other Pain Drugs 2016-11-13T05:00:00Z Now so-called surrogate endpoints—such as how the agent affects tumor growth or levels of certain tumor-related proteins—are used as ways to validate the effectiveness of a new drug. Why New Cancer Drugs May Not Be As Successful As They Seem 2016-11-09T05:00:00Z Given that so few participants reached ASTIC's demanding endpoint, the researchers concluded that the trial had failed, leading some to write off these transplants for IBD. Cell-based therapy: Cells on trial : Nature : Nature Research 2016-12-20T05:00:00Z It is a way station rather than an endpoint. ‘Everyone Needs to Act’: What to Expect From Climate Talks in Morocco 2016-11-03T04:00:00Z He says investors should look at security vendors that can administer protection, detection and remediation as security platforms within a larger business organization, while providing traffic visibility from the endpoint to the cloud. How to Buy Security Technology Stocks 2016-10-19T04:00:00Z As Witt’s image of the Epcot monorail suggests, she preferred to see it as an endpoint, the moment that would bring the aimless liaisons of her single years to a full stop. “Future Sex”: Adventures in an Erotic Wonderland 2016-10-10T04:00:00Z Societal change so profound that no single policy or set of policies could address or deliver seems to be movement’s endpoint, and success a distant speck of possibility on a far-off horizon. Black Lives Matter tactics prompt questions about true aims of social justice movement 2016-10-04T04:00:00Z “It definitely can be a lifesaver. The trial's very strange endpoint doesn't reflect the potency of this strategy.” Cell-based therapy: Cells on trial : Nature : Nature Research 2016-12-20T05:00:00Z For a younger generation, Shimon was probably remembered more for a peace process that never reached its endpoint. Read Remarks from President Obama at Shimon Peres' Memorial 2016-09-30T04:00:00Z Like the seconds before you first danced the "Macarena" or were asked "Who Let the Dogs Out," this moment is an endpoint of a phase of your... Night mode is the greatest 2016-09-27T04:00:00Z As Caulfield explains, the “studies are often small, they use a very particular kind of compound, and the endpoints are often quite subjective”. Are skin serums miracle workers or the purest distillation of beauty industry BS? 2016-09-16T04:00:00Z Because the ultimate endpoint of keeping out mitts off experience that doesn’t belong to us is that there is no fiction. Lionel Shriver's Controversial Cultural Appropriation Speech 2016-09-14T04:00:00Z Such a high bar — designed to reflect the risk associated with the treatment — meant that only two people in the treatment group reached the endpoint, compared with one in the control group. Cell-based therapy: Cells on trial : Nature : Nature Research 2016-12-20T05:00:00Z "For example, many local authority staff used mobile digital devices that represented 'unsecured endpoints', potentially allowing unauthorised access to the PSN." Government data security slammed in new report - BBC News 2016-09-13T04:00:00Z Step two is to identify specific tests for each endpoint. Rethink how chemical hazards are tested 2016-08-15T04:00:00Z Kindness carries with it a commitment to a certain way of thinking and being rather than to a particular pre-defined endpoint. We all want our doctors to be kind. But does kindness actually help us get well? 2016-08-11T04:00:00Z He shifted his endpoint from New York City to Tybee Island, Ga., and finished the 2,500-mile run in 60 days. Running Across America 2016-08-11T04:00:00Z "While we are disappointed CheckMate -026 did not meet its primary endpoint in this broad patient population, we remain committed to improving patient outcomes through our comprehensive development program." Bristol-Myers Stock Collapses After Disastrous Cancer Study Failure (BMY) 2016-08-05T04:00:00Z If taste is globalized, then the logical endpoint is a world in which aesthetic diversity decreases. How Silicon Valley helps spread the same sterile aesthetic across the world 2016-08-03T04:00:00Z The highway, called Wapello Road in town, passes several gas stations, a restaurant and grocery store before continuing north to its final endpoint in Minnesota. US 61 to bypass Mediapolis, draws safety concerns 2016-07-23T04:00:00Z “Just Another Version of You” hits all these points dutifully but, understandably, has trouble finding a natural endpoint. ‘Norman Lear: Just Another Version of You’: Homage to a visionary TV producer 2016-07-21T04:00:00Z For many liberals, of course, Trump is merely the natural endpoint of Republican evolution since the late 1960s. Never-Trump Confidential 2016-07-18T04:00:00Z In fact, it should be the endpoint of education, to nurture the growth of knowledge . So Many Research Scientists, So Few Openings as Professors 2016-07-14T04:00:00Z Firstly, that company could cut support for older devices — turn off the servers that keep those old thermostats running, or simply change the endpoint it connects to so it doesn’t function anymore. The Internet of Things has a dirty little secret: it's not really yours 2016-07-12T04:00:00Z |
| 随便看 |
|
英语例句辞典收录了117811条英语例句在线翻译词条，基本涵盖了全部常用单词及词组的例句翻译及用法，是英语学习的有利工具。