单词 | endothelial |
例句 | "If the weight goes down and the inflammation goes down, then the endothelial function, or the workings of the blood vessel, improves," she added. Chicago woman loses 143 pounds, reverses diabetes: Expert weighs in 2022-02-11T05:00:00Z "Several studies have determined that heart disease can be linked to oxidative stress, inflammation, and endothelial damage. Resveratrol has been shown to reduce oxidative stress, stimulate endothelial production of nitric oxide, and inhibit vascular inflammation." These are the best foods for your heart, experts say 2022-02-01T05:00:00Z Importantly, this trend was much stronger pronounced in vascular endothelial cells than lung epithelial cells. Human Lung Chip leveraged to faithfully model radiation-induced lung injury 2023-10-17T04:00:00Z "We reduce the effects of the stressor on endothelial cells and we improve regenerative processes, accelerating healing," Komarova said. New strategy for eye condition could replace injections with eyedrops 2023-10-03T04:00:00Z When they searched the literature, they found that other hormone-degrading enzymes—such as one called 17-beta-HSD, which degrades testosterone—are present in mouse brains’ endothelial cells. What turns an ant into a soldier or a forager? It may be all in their heads 2023-09-14T04:00:00Z Ranibizumab injections into the eye can block the action of vascular endothelial growth factor, which promotes growth of new blood vessels. NHS to offer sight-saving drug to premature babies 2023-07-03T04:00:00Z The endothelial lining of the nasal cavity also contains tiny hairlike projections, called cilia. Fundamentals of Biology 2015-01-01T00:00:00Z To more systematically understand the cellular changes triggered by radiation in the Lung Chip, and identify potential drug targets, the researchers analyzed the complete gene expression programs of epithelial and endothelial cells over time. Human Lung Chip leveraged to faithfully model radiation-induced lung injury 2023-10-17T04:00:00Z Even subtle disruption of endothelial cells in the brain could contribute to cognitive dysfunction. Long COVID Now Looks like a Neurological Disease, Helping Doctors to Focus Treatments 2023-02-14T05:00:00Z It is also possible that covid causes long-term damage to the endothelial cells that line blood vessels, and that such damage is leading to persistent symptoms. Opinion | The pandemic after the pandemic: Long covid haunts millions of people 2023-02-08T05:00:00Z We also found that Wnt2 and Wnt9b were located in the endothelial cells lining the blood vessels in zone 3 of the liver, an area that plays a role in a number of metabolic functions. Helping the liver regenerate itself could give patients an option other than a transplant 2022-11-03T04:00:00Z The first tunic is a smooth, inner lining of endothelial cells that are in contact with the red blood cells. Biology for AP Courses 2022-06-09T00:00:00Z Recall that cells and the medium-to-large proteins cannot pass between the podocyte processes or through the fenestrations of the capillary endothelial cells. Anatomy and Physiology 2013-06-19T00:00:00Z The coronavirus may damage blood vessels and the lining of the vessels, called the endothelium, as it binds to the molecular receptors that are plentiful on endothelial cells. Can COVID lead to impotence? 2022-05-05T04:00:00Z One possible mechanism is inflammation of the endothelial cells that line the inside of the heart and blood vessels, Al-Aly says. COVID-19 takes serious toll on heart health—a full year after recovery 2022-02-08T05:00:00Z Eliminating the two Wnt genes from endothelial cells also completely stopped liver cell division, and thus regeneration, after partial surgical removal of the liver. Helping the liver regenerate itself could give patients an option other than a transplant 2022-11-03T04:00:00Z The endothelial tunic is continuous with the endocardium of the heart. Biology for AP Courses 2022-06-09T00:00:00Z Some white blood cells have the ability to cross the endothelial layer that lines blood vessels and enter adjacent tissues. Anatomy and Physiology 2013-06-19T00:00:00Z Jannini said he suspected the risk was higher in patients who suffered from pneumonia accompanying COVID-19, which triggers inflammation of the blood vessels — specifically, endothelial cells that line the body’s blood vessels. COVID-19 and lasting erectile dysfunction: Here's what we know 2021-07-06T04:00:00Z When COVID-19 infections cause a blood vessel dysfunction known as endothelial dysfunction, it can damage the tissues that receive their blood supply from the malfunctioning small vessels. COVID-19 may increase chance of erectile dysfunction, studies say 2021-05-13T04:00:00Z Over the course of two days, we gave this drug to mice that were genetically engineered to lack Wnt2 and Wnt9b in their liver endothelial cells. Helping the liver regenerate itself could give patients an option other than a transplant 2022-11-03T04:00:00Z In capillaries, this single layer of cells is the location of diffusion of oxygen and carbon dioxide between the endothelial cells and red blood cells, as well as the exchange site via endocytosis and exocytosis. Biology for AP Courses 2022-06-09T00:00:00Z Thrombi are most commonly caused by vessel damage to the endothelial lining, which activates the clotting mechanism. Anatomy and Physiology 2013-06-19T00:00:00Z Not only is it found in the lungs, but also on nerve and endothelial cells. Their Teeth Fell Out. Was It Another COVID-19 Consequence? 2020-11-30T05:00:00Z Li said one theory is that the virus directly attacks endothelial cells. Clots, strokes and rashes: Is COVID a disease of the blood vessels? 2020-11-14T05:00:00Z But “we think that signaling is being changed by COVID,” Hunt says, because the virus injures endothelial cells, which respond to the insult by activating the coagulation system. Why COVID-19 is more deadly in people with obesity—even if they're young 2020-09-08T04:00:00Z The “leaky” connections between the endothelial cells of the glomerular capillary network allow solutes to pass through easily. Biology for AP Courses 2022-06-09T00:00:00Z A filtration membrane is formed by the fused basement membranes of the podocytes and the capillary endothelial cells that they embrace. Anatomy and Physiology 2013-06-19T00:00:00Z The authors also identified genes whose expression in endothelial cells correlates both positively and negatively with plasma-protein uptake. Unexpected amount of blood-borne protein enters the young brain 2020-06-30T04:00:00Z "The endothelial cells get leaky, so instead of being like saran wrap, it turns into a sieve and then it allows fluid from the bloodstream to accumulate in the air spaces," Harvard's Libby said. Clots, strokes and rashes: Is COVID a disease of the blood vessels? 2020-11-14T05:00:00Z They found that gene-expression changes were more evident in fibroblasts and endothelial cells than in epithelial cells. An antiviral response beyond immune cells 2020-06-30T04:00:00Z Monagle is trying to understand what happens when the virus enters endothelial cells. Why do children avoid the worst coronavirus symptoms? The answer might lie in their arteries 2020-06-10T04:00:00Z This epithelium is extremely thin and borders the endothelial membrane of capillaries. Anatomy and Physiology 2013-06-19T00:00:00Z And they warn their fellow endothelial cells to be on alert for invaders. Blood vessel attack could trigger coronavirus’ fatal ‘second phase’ 2020-06-02T04:00:00Z Those reveal that the virus warps a critical piece of our vascular infrastructure: the single layer of cells lining the inside of every blood vessel, known as the endothelial cells or simply the endothelium. Clots, strokes and rashes: Is COVID a disease of the blood vessels? 2020-11-14T05:00:00Z They also found inflammatory cells associated with endothelial cells in his heart, small bowel and lungs. Coronavirus is a blood vessel disease, scientists find — and its mysteries suddenly make sense 2020-06-01T04:00:00Z Some evidence suggests that the coronavirus may directly infect the endothelial cells that line the inside of blood vessels, causing injury and swelling that draws proteins that promote clotting, Dr. Cuker said. Coronavirus May Pose a New Risk to Younger Patients: Strokes 2020-05-14T04:00:00Z In contrast, the thicker stratum functionalis layer contains the glandular portion of the lamina propria and the endothelial tissue that lines the uterine lumen. Anatomy and Physiology 2013-06-19T00:00:00Z Together with the activated endothelial cells, the immune cells release a host of signaling molecules, including interleukins, which raise local blood pressure and weaken cell junctions. Blood vessel attack could trigger coronavirus’ fatal ‘second phase’ 2020-06-02T04:00:00Z Lab experiments have shown that the coronavirus can infect engineered human endothelial cells. Clots, strokes and rashes: Is COVID a disease of the blood vessels? 2020-11-14T05:00:00Z This causes disruption of junctions between adjoining endothelial cells, opening the BBB in brain regions involved in learning and memory. Risk factor for Alzheimer’s disease breaks the blood–brain barrier 2020-04-28T04:00:00Z This movement is aided by endothelial cells, which demarcate the border between blood and tissue, and which produce a panoply of monocyte-attracting chemical messengers, enabling monocyte surveillance of and migration across the blood-vessel wall. Platelets have a dangerous hold over immune cells in cardiovascular disease 2019-12-08T05:00:00Z Some large proteins in blood plasma can move into and out of the endothelial cells packaged within vesicles by endocytosis and exocytosis. Anatomy and Physiology 2013-06-19T00:00:00Z This emerging view of the key role of endothelial cells suggests that a number of existing drugs might dampen or even arrest the fatal second phase of the disease, Becker says. Blood vessel attack could trigger coronavirus’ fatal ‘second phase’ 2020-06-02T04:00:00Z It's also possible the problems begin elsewhere, and the endothelial cells sustain collateral damage along the way as the immune system reacts — and sometimes overreacts — to the invading virus. Clots, strokes and rashes: Is COVID a disease of the blood vessels? 2020-11-14T05:00:00Z Pegaptanib binds to and blocks the function of the protein vascular endothelial growth factor, leading to a reduction in the growth and permeability of blood vessels in the eye. RNA therapies explained 2019-10-15T04:00:00Z Similarly, the central nervous system has a backdoor that enables researchers to bypass the blood–brain barrier — a tightly-packed conformation of endothelial cells that protects the brain from potentially harmful molecules circulating in the blood. The challenge of delivering RNA-interference therapeutics to their target cells 2019-10-15T04:00:00Z Cytokines are glycoproteins secreted by a wide variety of cells, including red bone marrow, leukocytes, macrophages, fibroblasts, and endothelial cells. Anatomy and Physiology 2013-06-19T00:00:00Z Surrounding those sacs are capillaries lined like bricks with endothelial cells. Blood vessel attack could trigger coronavirus’ fatal ‘second phase’ 2020-06-02T04:00:00Z When that happens, endothelial cells change the way they function, he said. Clots, strokes and rashes: Is COVID a disease of the blood vessels? 2020-11-14T05:00:00Z The scientist was looking at: How did endothelial cells grow? Medicine in Space: What Microgravity Can Tell Us about Human Health 2019-08-07T04:00:00Z They observed genome-wide differences between the young and old animals in the gene-expression patterns of endothelial cells and of cells called microglia and oligodendrocytes. Infiltration of old brains by T cells causes dysfunction of neural stem cells 2019-07-02T04:00:00Z It is released naturally by endothelial cells but is also used in clinical medicine. Anatomy and Physiology 2013-06-19T00:00:00Z Typically taken to lower cholesterol, they also reduce inflammation and improve endothelial cell function. Blood vessel attack could trigger coronavirus’ fatal ‘second phase’ 2020-06-02T04:00:00Z In that case, the endothelial cells turn against their host and start to promote clotting and high blood pressure. Clots, strokes and rashes: Is COVID a disease of the blood vessels? 2020-11-14T05:00:00Z He injected a cancer drug, an antibody to vascular endothelial growth factor A, into the eye of the patient. A Streamlined Pathway to Drug Approval 2019-06-26T04:00:00Z Further neuroblast-cell profiling did not reveal any obvious similarities to other types of cell in the tumour microenvironment, such as immune or endothelial cells. Nerve cells from the brain invade prostate tumours 2019-05-14T04:00:00Z The platelets begin to clump together, become spiked and sticky, and bind to the exposed collagen and endothelial lining. Anatomy and Physiology 2013-06-19T00:00:00Z Mangalmurti welcomes such trials but cautions that patients may respond differently depending on how healthy their endothelial cells are to start. Blood vessel attack could trigger coronavirus’ fatal ‘second phase’ 2020-06-02T04:00:00Z The novel coronavirus triggers a condition seen in other cardiovascular diseases called endothelial dysfunction. Clots, strokes and rashes: Is COVID a disease of the blood vessels? 2020-11-14T05:00:00Z An enzyme shears VCAM1 off endothelial cells at roughly the same rate it is produced, so the total amount in cells stays fairly stable and the amount in circulation is a good proxy for this. How Young Blood Rejuvenates an Old Animal's Brain 2019-05-14T04:00:00Z Bursac has recently woven in more complexity, adding populations of endothelial cells, which develop into blood vessels, and fibroblast cells, which he realized can help the patch form and become stronger. Lab-grown patch of heart muscle and other cells could fix ailing hearts 2019-04-24T04:00:00Z The critical endothelial lining of the tunica intima is intact. Anatomy and Physiology 2013-06-19T00:00:00Z Damage to the endothelial cells also exposes the membrane underneath them. Blood vessel attack could trigger coronavirus’ fatal ‘second phase’ 2020-06-02T04:00:00Z A recent study found elevated levels of a protein produced by endothelial cells, called von Willebrand factor, that is involved in clotting. Clots, strokes and rashes: Is COVID a disease of the blood vessels? 2020-11-14T05:00:00Z The researchers’ working theory for what happens, is that cytokines in aged blood first trigger brain endothelial cells to produce more VCAM1. How Young Blood Rejuvenates an Old Animal's Brain 2019-05-14T04:00:00Z However, Neelapu notes that research reported last year suggests that the cytokines released by T cells might be linked to endothelial dysfunction and disruption of the blood–brain barrier. Genetically modified T cells target lymphoma 2018-11-13T05:00:00Z The wall of a capillary consists of the endothelial layer surrounded by a basement membrane with occasional smooth muscle fibers. Anatomy and Physiology 2013-06-19T00:00:00Z The endothelial and immune cells add fuel to the fire, recruiting additional clotting factors and platelets, which help form clots. Blood vessel attack could trigger coronavirus’ fatal ‘second phase’ 2020-06-02T04:00:00Z Figure 1 | Enhancing adhesion between a bacterium and an endothelial cell. Nanofibres induce remodelling of cell membranes 2018-11-04T04:00:00Z The glomerulus chip not only maintained healthy podocytes and endothelial cells, but its realistic mechanical environment actually developed the podocytes even further than any other method. Futuristic organ-on-a-chip technology now seems more realistic than ever 2018-10-21T04:00:00Z Analysis of the labelled cells revealed that EMPs actively migrate from the yolk sac into the embryo and differentiate into endothelial cells — reverting to their initial endothelial fate but now in an intraembryonic site. A dual origin for blood vessels 2018-09-25T04:00:00Z Continuous capillaries are characterized by a complete endothelial lining with tight junctions between endothelial cells. Anatomy and Physiology 2013-06-19T00:00:00Z Researchers are also uncertain about how to get endothelial cells in blood vessels to form the blood–brain barrier. How cerebral organoids are guiding brain-cancer research and therapies 2018-09-25T04:00:00Z Moderate exercise seems to hone endothelial and cardiac health, he says, probably in large part by increasing the flow of blood through blood vessels. Exercise vs. Standing? You Probably Need to Do Both 2018-06-13T04:00:00Z If growing endothelial cells is like baking from a cake-mix, growing realistic podocytes is more like finding yourself on salt flat with a bale of wheat, a hen, and a sugarcane. Futuristic organ-on-a-chip technology now seems more realistic than ever 2018-10-21T04:00:00Z EMP-derived endothelial cells are incorporated into mesoderm-derived blood vessels in developing organs such as the brain, liver and lung, forming a mosaic pattern across the vessel lining. A dual origin for blood vessels 2018-09-25T04:00:00Z The endothelial lining of the vessels arise from the angioblasts within these islands. Anatomy and Physiology 2013-06-19T00:00:00Z Among the protein's normal sources are fat cells, immune cells, and endothelial cells, which produce low baseline levels. What's your risk of kidney disease, heart attack, or diabetes? A single molecule can tell 2018-04-19T04:00:00Z Kieda’s lab combines melanoma and endothelial cells in a matrix composed of collagen, growth factors and a 3D scaffold called Matrigel. Cancer research with a human touch 2018-04-09T04:00:00Z This protein is induced under low-oxygen conditions and acts through receptors on vascular endothelial cells to induce proliferation, resulting in fragile new blood vessels prone to bleeding. A dark side to omega-3 fatty acids The authors also examined the gene-expression profiles of endothelial cells in blood vessels. A dual origin for blood vessels 2018-09-25T04:00:00Z Eventually, the muscular and endothelial components of the ductus arteriosus degenerate, leaving only the connective tissue component of the ligamentum arteriosum. Anatomy and Physiology 2013-06-19T00:00:00Z After two weeks, the researchers added specialized cells that line the inside of blood vessels, or endothelial cells. Scientists used human stem cells to build a new rat intestine 2017-10-10T04:00:00Z Chandan Sen, a physiologist at Ohio State, and his colleagues developed a genetic cocktail that rapidly converts skin cells into endothelial cells—the main component of blood vessels. Chip Reprograms Cells to Regenerate Damaged Tissue 2017-09-29T04:00:00Z Writing in the journal PNAS, the team reveal the missing link is a protein, known as vascular endothelial growth factor, which is made in the region of the pituitary gland that detects melatonin. Why do sheep get horny in winter? Because the light is baaad, says study 2017-03-06T05:00:00Z Whereas large sections of vascular smooth muscle are derived from the same developmental source, it seems that EMP-derived endothelial cells interlace with cells of direct mesodermal origin. A dual origin for blood vessels 2018-09-25T04:00:00Z Damage to this endothelial lining and exposure of blood to the collagenous fibers beneath is one of the primary causes of clot formation. Anatomy and Physiology 2013-06-19T00:00:00Z And high levels of three other biomarkers -- vascular endothelial growth factor, C-reactive protein, and tumor necrosis factor receptor 2 -- also indicated a similar heightening of stroke risk, the investigators said. Blood Test Might Someday Predict Your Stroke Risk 2016-08-24T04:00:00Z They said these results were especially evident among patients with Fuchs endothelial dystrophy -- a condition affecting a thin layer of cells that line the back of the cornea. Cornea Transplants Riskier for Women When They Come From Men? 2016-07-15T04:00:00Z Hendrix and colleagues discovered that cancer cells involved in vasculogenic mimicry release some of the same anticlotting molecules endothelial cells do. Tumors have found a bloody new way to grow and spread 2016-06-16T04:00:00Z Extending this idea, maybe the high percentage of EMP-derived endothelial cells in the liver is a factor in that organ’s remarkable capacity for regeneration. A dual origin for blood vessels 2018-09-25T04:00:00Z Small molecules, such as gases, lipids, and lipid-soluble molecules, can diffuse directly through the membranes of the endothelial cells of the capillary wall. Anatomy and Physiology 2013-06-19T00:00:00Z For this study, Cooke and his colleagues cultured the cells that line the walls of blood vessels, which are called endothelial cells. Clues to How Popular Heartburn Drug Might Harm Arteries 2016-05-10T04:00:00Z The shots deliver drugs that fight a substance called vascular endothelial growth factor, and thus shrink the growth of what amounts to an abnormal blood vessel harming the retina. Fighting Macular Degeneration 2016-03-19T04:00:00Z But to the scientists’ surprise, the networks lacked the endothelial cells that line normal blood vessels, suggesting that the cancers themselves formed the channels. Tumors have found a bloody new way to grow and spread 2016-06-16T04:00:00Z Plein and colleagues’ work will most certainly inspire investigators to pursue new experiments that explore the relationship between the origin of endothelial cells and their function. A dual origin for blood vessels 2018-09-25T04:00:00Z As interstitial pressure increases, the filaments pull on the endothelial cell flaps, opening up them even further to allow easy entry of fluid. Anatomy and Physiology 2013-06-19T00:00:00Z Protective endothelial cells produce substances that relax the blood vessel, and create a slick "Teflon" coating inside the vessel that prevents plaques or blood clots from sticking, Cooke said. Clues to How Popular Heartburn Drug Might Harm Arteries 2016-05-10T04:00:00Z However, recent studies show that endothelial cell damage persists long after delivery. Pregnancy and the Heart: a Difficult Pregnancy May Warn of Future Cardiovascular Risk 2016-02-01T05:00:00Z The protein, called CD59, normally stays on the surface of endothelial cells to protect them from part of the body's immune system, according to background notes with the study. Statins May Reduce Heart Risks Linked to Sleep Apnea: Study 2016-01-06T05:00:00Z In a paper in Nature, Plein et al.3 reveal a second origin for endothelial cells, and refine our understanding of the relationship between the endothelial and blood lineages. A dual origin for blood vessels 2018-09-25T04:00:00Z In the PCT, there is a single layer of simple cuboidal endothelial cells against the basement membrane. Anatomy and Physiology 2013-06-19T00:00:00Z The waste buildup caused endothelial cells to age rapidly, Cooke said, which could hamper their ability to protect blood vessels. Clues to How Popular Heartburn Drug Might Harm Arteries 2016-05-10T04:00:00Z Vasotide prevents the excessive growth of blood vessels, termed angiogenesis, by stopping a protein called vascular endothelial growth factor from binding to two receptors on blood-vessel walls, the study said. How the Brain Regulates Simultaneous Pains 2015-10-26T04:00:00Z In the small, laboratory study, researchers closely examined endothelial cells, which line the inside of blood vessels. Statins May Reduce Heart Risks Linked to Sleep Apnea: Study 2016-01-06T05:00:00Z Atherosclerosis and endothelial dysfunction are closely related processes that are both fueled by smoking, lack of physical activity, obesity, diabetes, high blood pressure and high cholesterol, all well-known players in cardiovascular disease. Beyond Sex: Erectile Dysfunction Could Spell Heart Trouble 2015-10-14T04:00:00Z It is produced in the lungs but binds to the surfaces of endothelial cells in the afferent arterioles and glomerulus. Anatomy and Physiology 2013-06-19T00:00:00Z But results showed an improvement in their fitness levels, and in endothelial function -- a measure of how well the blood vessels dilate and constrict in response to blood flow. Exercise Boosts Obese Kids' Heart Health 2015-08-10T04:00:00Z The channels are separated by a porous membrane which is lined on the top with epithelial cells derived from human lung alveoli, and on the bottom with endothelial cells from blood vessels. Towards a body-on-a-chip 2015-06-11T04:00:00Z To mimic the conditions of the lung within a microfluidic device, Ingber's team cultivated epithelial cells derived from human alveoli and endothelial cells derived from blood vessels on either side of a porous polymer membrane. Artificial organs: Honey, I shrunk the lungs : Nature : Nature Publishing Group 2015-03-24T04:00:00Z Impaired function in the blood vessel's walls -- called reduced endothelial function -- is the earliest sign of heart disease, the researchers noted. Early Onset Hot Flashes May Point to Raised Heart Disease Risk 2015-03-05T05:00:00Z Some cells have the ability to cross the endothelial layer that lines vessels and enter adjacent tissues. Anatomy and Physiology 2013-06-19T00:00:00Z "I think that improvement in endothelial function is very important," Church said. Exercise Boosts Obese Kids' Heart Health 2015-08-10T04:00:00Z Further analyses indicated that consumption of more lean fish and raw vegetables and fewer high-fat dairy products was associated with less endothelial dysfunction. Healthy Diet May Curb Dysfunction that Leads to Cardiovascular Disease 2015-01-16T05:00:00Z In my lab, for example, I study endothelial cells, which line the insides of our veins, arteries, and capillaries. How 3-D Printing Is Changing Medicine 2014-11-17T05:00:00Z Tea is thought to offer endothelial protection by helping blood vessels relax, allowing blood to flow more freely. This Kind of Tea Lowers Blood Pressure 2014-10-21T04:00:00Z Interstitial fluid slips through spaces between the overlapping endothelial cells that compose the lymphatic capillary. Anatomy and Physiology 2013-06-19T00:00:00Z But what is now a virus that latches onto receptors outside endothelial cells lining the circulatory system won’t change into one that can attach to the alveolar cells of the lungs. Five myths about Ebola Intravital imaging studies showed that macrophages, along with tumour cells and endothelial cells, form a structure that pumps tumour cells into the bloodstream — a key step in metastasis. Imaging: Cancer caught in the act 2014-05-07T17:20:20.854Z The total number of endothelial cells present, and therefore the percentage of dead endothelial cells, was estimated from the total number of pericytes, assuming a 1:3 ratio of pericytes to endothelial cells. Capillary pericytes regulate cerebral blood flow in health and disease 2014-04-04T18:24:22.627Z Hall . report that pericytes, which surround the endothelial cells that form capillaries, are involved in regulating cerebral blood flow. Vascular biology: Brain vessels squeezed to death 2014-04-04T18:23:16.270Z When interstitial pressure is low, the endothelial flaps close to prevent “backflow.” Anatomy and Physiology 2013-06-19T00:00:00Z We report that endothelial lamellipodia surround emboli within hours of occlusion, markedly reducing hemodynamic washout and tissue plasminogen activator–mediated fibrinolysis in mice. [Research Articles] Angiophagy Prevents Early Embolus Washout But Recanalizes Microvessels Through Embolus Extravasation 2014-03-05T19:25:27.845Z Macrophages cause the endothelial cells to lose contact with each other, opening a hole in the vessel wall and allowing tumour cells to stream out of the tissue and into the bloodstream. Imaging: Cancer caught in the act 2014-05-07T17:20:20.854Z Blood and lymphatic endothelial cells never intermixed during vessel development, nor did blood and lymphatic capillaries anastomose under the described circumstances. [Research Articles] Bioengineering Dermo-Epidermal Skin Grafts with Blood and Lymphatic Capillaries 2014-01-29T19:55:08.973Z Later, recovery of endothelial Angiopoetin-2 expression facilitates angiogenesis in the regenerating liver in a vascular endothelial growth factor receptor 2–dependent manner. [Report] Endothelial Cell-Derived Angiopoietin-2 Controls Liver Regeneration as a Spatiotemporal Rheostat 2014-01-23T19:26:26.766Z During this process endothelial cells were also released into the blood, the researchers said. Heart attack 'leaves cellular trace' 2014-01-10T02:10:51Z Studies in recent years concluded that laughter “reduces arterial wall stiffness” and “improves endothelial function.” Well: Who Says Laughter’s the Best Medicine? 2013-12-20T05:01:04Z A growing library of molecular markers has given researchers the ability to visualize up to eight different kinds of cells and structures, including various immune-system cells and the endothelial cells that line blood vessels. Imaging: Cancer caught in the act 2014-05-07T17:20:20.854Z These are support cells, providing structural support for the newly formed blood vessels, promoting the survival of the endothelial cells, and guiding the sprouting of new blood vessels. The Hallmarks of Cancer 5: Sustained Angiogenesis 2013-10-19T00:45:00.460Z This genetic strategy initially induced a dense network of loosely adjoined endothelial cells and pericytes near lateral ventricles, similar to the immature vascular rete in human fetal brains. [Research Articles] Overexpression of Vascular Endothelial Growth Factor in the Germinal Matrix Induces Neurovascular Proteases and Intraventricular Hemorrhage 2013-07-10T18:25:11.093Z The team, at the Scripps Research Institute in California, looked for circulating endothelial cells in the blood of patients. Heart attack 'leaves cellular trace' 2014-01-10T02:10:51Z Those without endothelial cells failed to create a network of blood vessels. Stem-cell therapies: Prometheus unbound 2013-07-03T17:33:19Z This may reflect stromal or endothelial cell contributions, or tumour cell heterogeneity. Comprehensive molecular characterization of clear cell renal cell carcinoma 2013-07-03T17:20:51.807Z The walls of all these vessels are lined with endothelial cells. Messing With the Blood-Brain Barrier May Be Key to Treating a Host of Diseases (preview) 2013-06-12T11:15:00.430Z The TNF then binds preferentially to the endothelial cells in a tumour's blood vessels and kills them. Biomedicine: The new gold standard 2013-03-13T18:21:23.433Z At the same time, endothelial and smooth muscle cells begin to pump out chemicals that attract monocytes. Pathology: At the heart of the problem 2013-01-30T18:23:07.253Z An alternative technique is to deliver a protein called vascular endothelial growth factor, or VEGF, to promote blood-vessel growth in the heart. Nanotechnology Holds Promise for Heart Patients 2012-08-08T18:25:00Z First the investigators looked at variations in a well-known gene, endothelial lipase, that affects only HDL. HDL ?Good Cholesterol? Found Not to Cut Heart Risk 2012-05-17T14:54:10Z Two years ago the Mayo clinic released a study showing a direct tie between endothelial... Scientists hunt ways to stall Alzheimer's earlier 2012-05-16T13:31:05Z Mitochondrial network of an endothelial cell is shown in green Research projects evolve in a fortuitous manner, often guided by a convergence of novel observations, intuition, helpful colleagues and unique personal circumstances. Dynamic Mitochondrial Networks in Cancer 2012-03-29T15:45:03.977Z The LDL in artery walls prompts endothelial cells, which line the vessels, to produce sticky molecules that snag macrophage precursor cells, monocytes, from the blood. Pathology: At the heart of the problem 2013-01-30T18:23:07.253Z They counted lots of the endothelial cells floating in the heart attack victims' blood, and very little in the healthy people's blood. Doctors find clue in quest to predict heart attack 2012-03-21T23:26:08Z When the vessel is damaged, endothelial cells break away and enter the bloodstream. Doctors find clue in quest to predict heart attack 2012-03-22T00:13:03Z Such tumors are to be regarded as of an endothelial rather than epithelial character, and as such their histogenesis falls under the general laws of the development of tissues. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z A tightly controlled Notch4 molecular switch in blood vessel endothelial cells induces regression of arteriovenous malformations in mice. [Focus] Arteriovenous Malformations in Five Dimensions 2012-01-18T20:25:08.187Z Using in vitro and ex vivo models of vessel wall stiffness and aging, we show that stiffening of extracellular matrix within the intima promotes endothelial cell permeability—a hallmark of atherogenesis. [Research Articles] Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration 2011-12-07T19:55:09.007Z These are endothelial tubes in the substance of the organs, the tissue of the organ giving them the necessary support. Arteriosclerosis and Hypertension: with Chapters on Blood Pressure, 3rd Edition. 2011-10-11T02:01:07.890Z The new technique involves tracking a type of cell in the blood called a circulating endothelial cell. Doctors find clue in quest to predict heart attack 2012-03-22T00:13:03Z A granulation-tissue is formed at the periphery, which extends into the infarcted region, very much as the endothelial and vascularized growth extends into a thrombus. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z However, these stents may still lead to in-stent stenosis; they also show increased rates of late stent thrombosis, an obstacle to optimal revascularization possibly related to endothelial recovery. [Research Articles] Neutrophil-Derived Cathelicidin Protects from Neointimal Hyperplasia 2011-10-05T18:55:12.217Z This increase in endothelial permeability results in increased leukocyte extravasation, which is a critical step in atherosclerotic plaque formation. [Research Articles] Age-Related Intimal Stiffening Enhances Endothelial Permeability and Leukocyte Transmigration 2011-12-07T19:55:09.007Z The essential portion of any blood vessel is the endothelial tube, composed of flat cells cemented together by intercellular substance and having no stomata between the cells. Arteriosclerosis and Hypertension: with Chapters on Blood Pressure, 3rd Edition. 2011-10-11T02:01:07.890Z One key question is how long before a heart attack the circulating endothelial cells appear. Doctors find clue in quest to predict heart attack 2012-03-22T00:13:03Z The compound also prevented the storms in these animals, suggesting that endothelial cells, not lymphocytes, orchestrate cytokine release. Surprising Cells Rein In Killer Flu 2011-09-15T17:00:00Z We decided to address this problem by comparing thee groups of endothelial cells -- ones derived from lungs affected with fibrosis, with hypertension, and with emphysema. Close Encounters of Science and Medicine 2011-06-23T13:15:02.633Z It took advantage of the brain’s own mechanism for getting a necessary nutrient, iron, across the lining of endothelial cells that form the blood-brain barrier. Tricking the Brain Into Taking Its Medicine 2011-05-25T19:35:58Z The whole vascular system, including the heart, has an endothelial lining, which may constitute a distinct inner coat, the tunica intima, or may be without coverings, as in the case of the capillaries. Arteriosclerosis and Hypertension: with Chapters on Blood Pressure, 3rd Edition. 2011-10-11T02:01:07.890Z The researchers found substantially more endothelial microparticles in smokers than in the nonsmokers. Blood Tests Could Forewarn of Emphysema 2011-03-16T17:07:00Z This paper "points to a clear role for endothelial cells in influenza pathogenesis," says immunologist W. Conrad Liles of the University of Toronto in Canada. Surprising Cells Rein In Killer Flu 2011-09-15T17:00:00Z The team made two cell types: muscle cells for the tube's outer layer and endothelial cells -- cells that line blood vessels and other tubular structures -- for the inner layer. Scientists grow viable urethras from boys' cells 2011-03-07T23:34:40Z By means of endothelial or mesothelial membranes the surfaces of the parts covered by them are rendered very smooth, so that movement over the surface is greatly facilitated. Encyclopaedia Britannica, 11th Edition, Volume 9, Slice 6 "English Language" to "Epsom Salts" 2011-02-19T03:00:59.807Z The intima is a thin line composed of endothelial cells. Arteriosclerosis and Hypertension: with Chapters on Blood Pressure, 3rd Edition. 2011-10-11T02:01:07.890Z The role of FAS and lipid abnormalities is an "exciting new idea" in understanding endothelial dysfunction, according to King, but their specific contribution to the microvascular complications of diabetes is less clear. Mouse Study Reveals Mechanism behind Diabetes Blood Vessel Damage 2011-02-18T15:15:04.180Z The drug, bevacizumab, is used against some cancers because it inhibits manufacture of a protein called vascular endothelial growth factor, or VEGF, that drives vessel growth. Saving Preemies' Vision 2011-02-17T15:33:00Z Those vessels were “seeded” inside with natural vessel-lining cells called endothelial cells. Bioengineering Better Blood Vessels 2011-02-03T15:46:00Z These cells develop from that portion of the mesoderm known as the mesothelium, and are therefore frequently termed mesothelial, though by many they are also included as endothelial cells. Encyclopaedia Britannica, 11th Edition, Volume 9, Slice 6 "English Language" to "Epsom Salts" 2011-02-19T03:00:59.807Z The last two are probably the same process, the connective tissue having its origin in the proliferated endothelial cells. Arteriosclerosis and Hypertension: with Chapters on Blood Pressure, 3rd Edition. 2011-10-11T02:01:07.890Z A, tunica adventitia; E, elastic coat; M, muscular coat; F, fenestrated coat; En, endothelium continuous with the endothelial wall of C, the capillaries. Encyclopaedia Britannica, 11th Edition, Volume 2, Slice 6 "Armour Plates" to "Arundel, Earls of" The inner surface has the appearance of a serous membrane, and when examined microscopically is seen to consist of a layer of squamous endothelial cells. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 4 "Bradford, William" to "Brequigny, Louis" In people, a vessel recipient would donate his or her own endothelial cells for placement in a bioengineered vessel, which would delay surgery only a few weeks, the researchers say. Bioengineering Better Blood Vessels 2011-02-03T15:46:00Z There is further a great tendency for the endothelial cells to form muscles, and this is especially pronounced in the small arm-sinus, where a conspicuous muscle is built up. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 3 "Borgia, Lucrezia" to "Bradford, John" In the absence of plain muscular fibres contraction and dilatation of the capillaries can only be effected by a corresponding contraction and expansion of the nuclei of the endothelial cells. On Snake-Poison: its Action and its Antidote Most internal of all is a layer of endothelial cells, which form the free surface over which the blood flows. Encyclopaedia Britannica, 11th Edition, Volume 2, Slice 6 "Armour Plates" to "Arundel, Earls of" Microscopically, it may contain some large endothelial cells and a few lymphocytes, or may be entirely devoid of cells. Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. The wall of capillaries consists of a single layer of endothelial cells. Manual of Surgery Volume First: General Surgery. Sixth Edition. Some of the endothelial cells lining the coelom are ciliated, the cilia keeping the corpusculated fluid contents in movement. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 3 "Borgia, Lucrezia" to "Bradford, John" This was formerly believed to be an endothelioma derived from a proliferation of the endothelial cells lining the lymph spaces and blood vessels of the gland. Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. The sections show proliferation of endothelial cells, the formation of numerous giant cells quite unlike those of tuberculosis and a progressive fibrosis. Manual of Surgery Volume First: General Surgery. Sixth Edition. The synovia owes its lubricating property to mucin, derived from the solution of the endothelial cells on the free surface of the synovial layer. Manual of Surgery Volume Second: Extremities—Head—Neck. Sixth Edition. Gouty Teno-synovitis.—A deposit of urate of soda beneath the endothelial covering of tendons or of that lining their sheaths is commonly met with in gouty subjects. Manual of Surgery Volume First: General Surgery. Sixth Edition. Others of the endothelial cells show a great tendency to form muscle fibres. Encyclopaedia Britannica, 11th Edition, Volume 4, Slice 3 "Borgia, Lucrezia" to "Bradford, John" |
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