单词 | endonuclease |
例句 | But the challenge was how to introduce the endonuclease gene and its associated genetic payload to a spot in the genome where it would work safely without inadvertently affecting other aspects of the animal’s physiology. Gene Drives Could Fight Malaria and Other Global Killers but Might Have Unintended Consequences 2023-01-13T05:00:00Z It is the first drug in a new class called endonuclease inhibitors. FDA Approves a Fast-acting Flu Drug that is Taken in a Single Dose 2018-10-25T04:00:00Z It is an endonuclease inhibitor; this is the first new class of influenza drugs to hit the market in over two decades. A Flu Drug May be Poised to Upend Treatment in U.S. 2018-06-28T04:00:00Z Researchers need only an enzyme that cuts DNA, such as the endonuclease Cas9, and a guide RNA molecule that directs the enzyme to cut the gene of interest. Gene therapy: Erasing sickle-cell disease : Nature : Nature Research 2017-09-26T04:00:00Z "And given the state of the chimeric restriction endonuclease art prior to the patent's 1999 date, there are some serious doubts as to its validity. We'll see what Cellectis does with it." Dramatic twists could upend patent battle over CRISPR genome-editing method 2016-10-05T04:00:00Z They did this by injecting the cells with a segment of RNA that was designed to produce a DNA-cutting enzyme known as an endonuclease. DNA editing in mouse embryos prevents disease 2015-04-22T04:00:00Z Inserting the strand into cells spurs their mitochondria to produce the enzyme, known as a restriction endonuclease, which cuts faulty mitochondrial DNA and leads to its destruction. Technique aims to cut disease-causing mutations out of eggs and embryos 2015-04-23T04:00:00Z Many of these will also carry the endonuclease, so the same thing will happen in the next generation. X marks the spot 2014-06-12T04:00:00Z This gene produces an enzyme called an "endonuclease" which chops up DNA when it recognises a particular sequence. GM strains crash mosquito population 2014-06-10T04:00:00Z The scientists injected mosquitoes with a gene from slime mould – a homing endonuclease called I-PpoI – which attached itself to their X chromosome during the male’s sperm-making process and effectively shredded part of the chromosome’s DNA. GM mosquitoes a ‘quantum leap’ towards tackling malaria 2014-06-10T04:00:00Z The second strategy aims to deliver an enzyme called an endonuclease that specifically clips HIV DNA lurking in chromosomes. Big Bolus for HIV/AIDS Cure Research 2011-07-11T23:59:37Z They inserted a gene into the mosquito DNA which is very good at looking after its own interests - a homing endonuclease called I-SceI. GM mosquitoes offer malaria hope 2011-04-20T23:46:08Z Eventually natural selection will find a way around the endonuclease, and the number of mosquitoes will return to normal. X marks the spot 2014-06-12T04:00:00Z In our mosquitoes the homing endonuclease gene is only passed on... directly to the carrier's offspring. Scientists manipulate mosquitoes in malaria fight 2011-04-20T19:13:01Z As a result the homing endonuclease gene is copied. GM mosquitoes offer malaria hope 2011-04-20T23:46:08Z |
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