| 单词 | EBV |
| 例句 | The team checked for other infections, such as cytomegalovirus, but only EBV had a crystal clear connection with the neurodegenerative disease. Is a virus we all have causing multiple sclerosis? 2022-04-13T04:00:00Z For years, EBV has been thought to be a possible cause for MS, a chronic disease affecting the central nervous system. Multiple sclerosis and commonly found Epstein-Barr virus likely to be linked, major study says 2022-01-14T05:00:00Z “These findings cannot be explained by any known risk factor for MS and suggest EBV as the leading cause of MS,” the researchers wrote. Epstein-Barr Virus Found to Trigger Multiple Sclerosis 2022-01-13T05:00:00Z EBV, a herpesvirus that infects most people by adolescence and then lies latent in B cells throughout life, has long been a prime suspect. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z Computer models will then convert the data into EBV values and biodiversity “indicators,” which can be compared globally. Satellites offer new ways to study ecosystems—and maybe even save them 2021-11-17T05:00:00Z Prof Ascherio says the study is the "first" compelling evidence that EBV is causing the disease. Is a virus we all have causing multiple sclerosis? 2022-04-13T04:00:00Z The study said contracting EBV could increase by 32 times the risk of developing MS, and while the findings were praised by experts, they also noted that the results did not provide a definitive link. Multiple sclerosis and commonly found Epstein-Barr virus likely to be linked, major study says 2022-01-14T05:00:00Z In an accompanying commentary, immunologists William H. Robinson and Lawrence Steinman, both at Stanford University, wrote, “These findings provide compelling data that implicate EBV as the trigger for the development of MS.” Epstein-Barr Virus Found to Trigger Multiple Sclerosis 2022-01-13T05:00:00Z Ideally, researchers would track a group of young people who haven’t yet been infected by EBV to see whether those who contract the infection are more likely to develop MS than those who don’t. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z This variation, an EBV called ecosystem phenology, depends on rainfall. Satellites offer new ways to study ecosystems—and maybe even save them 2021-11-17T05:00:00Z It will take a study that is able to prevent people catching EBV - and see if that also prevents multiple sclerosis - to definitively prove the virus has a critical role in the disease. Is a virus we all have causing multiple sclerosis? 2022-04-13T04:00:00Z Nonetheless, the research suggests that many MS cases could be prevented by stopping EBV infection, Ascherio said, adding that targeting the virus could also lead to a cure for MS. Multiple sclerosis and commonly found Epstein-Barr virus likely to be linked, major study says 2022-01-14T05:00:00Z Epidemiologist Alberto Ascherio, senior author of the new study, says, “The bottom line is almost: if you’re not infected with EBV, you don’t get MS. It’s rare to get such black-and-white results.” Epstein-Barr Virus Found to Trigger Multiple Sclerosis 2022-01-13T05:00:00Z That means an EBV infection multiplies a person’s risk of MS 32-fold, comparable to the increase in risk of getting lung cancer from heavy smoking, Ascherio says. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z But whether the world is ready to embrace remote sensing in general and the EBV strategy, in particular, is unclear. Satellites offer new ways to study ecosystems—and maybe even save them 2021-11-17T05:00:00Z Prof Bill Robinson, an immunologist at Stanford University in California, was an EBV sceptic until a couple of years ago. Is a virus we all have causing multiple sclerosis? 2022-04-13T04:00:00Z Most people are infected by EBV as children. Multiple sclerosis and commonly found Epstein-Barr virus likely to be linked, major study says 2022-01-14T05:00:00Z Thirty-five of the people who developed MS and 107 controls tested negative for EBV initially. Epstein-Barr Virus Found to Trigger Multiple Sclerosis 2022-01-13T05:00:00Z To bolster their case, they showed that people who eventually developed MS had a rise in levels of a protein linked to neural degradation after their EBV infection. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z CMV and EBV are both known for causing different strains of mono. NASA study finds herpes viruses reactivate in astronauts, what causes flare-ups in space 2019-03-18T04:00:00Z "I was dismissive, everybody has EBV so there's no way it can really cause MS." Is a virus we all have causing multiple sclerosis? 2022-04-13T04:00:00Z The second, a control group of 90 people who did not have MS, only contained 51 EBV cases. Multiple sclerosis and commonly found Epstein-Barr virus likely to be linked, major study says 2022-01-14T05:00:00Z Antivirals that target EBV in infected B cells are one possibility. Epstein-Barr Virus Found to Trigger Multiple Sclerosis 2022-01-13T05:00:00Z “How do you explain the fact that you don’t get MS unless you get EBV? There is no other alternative explanation,” he says. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z More than half a century ago, EBV was identified as the first virus to help trigger a cancer in humans — Burkitt’s lymphoma, a type of non-Hodgkin’s lymphoma that typically occurs in children in Africa. Building a better lymphoma vaccine 2018-11-13T05:00:00Z His study, published in the journal Nature, showed the myelin sheath suffers from mistaken identity and is attacked by a confused part of the immune system that thinks it is fighting EBV. Is a virus we all have causing multiple sclerosis? 2022-04-13T04:00:00Z The risk of getting multiple sclerosis increased by 32-fold following an EBV infection, the researchers’ analysis found. Multiple sclerosis and commonly found Epstein-Barr virus likely to be linked, major study says 2022-01-14T05:00:00Z And children infected with EBV are up to 50 times more likely to eventually develop lupus, which currently has no cure. How the virus behind ‘kissing disease’ may increase your risk for autoimmune diseases like lupus 2018-04-16T04:00:00Z And the study doesn’t explain why most people who get EBV don’t develop MS, says neurologist Emmanuelle Waubant of the University of California, San Francisco. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z But the lengthening list of human ills caused by EBV, including autoimmune diseases such as multiple sclerosis1, is prompting a rethink. Building a better lymphoma vaccine 2018-11-13T05:00:00Z Clearly this does not happen to everybody who is infected with EBV. Is a virus we all have causing multiple sclerosis? 2022-04-13T04:00:00Z Bruestle noted that all the people with EBV in the two groups were infected as adults. Multiple sclerosis and commonly found Epstein-Barr virus likely to be linked, major study says 2022-01-14T05:00:00Z So Harley’s team compared three sequencing data sets that show where EBV proteins land on the genome in B lymphocytes, the immune cells that run interference against the virus when someone becomes infected. How the virus behind ‘kissing disease’ may increase your risk for autoimmune diseases like lupus 2018-04-16T04:00:00Z Also dissatisfying is the lack of a known mechanism for how EBV might cause the immune attack. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z One problem facing vaccine researchers is the complicated life cycle of EBV. Building a better lymphoma vaccine 2018-11-13T05:00:00Z There are several companies already working on an EBV vaccine, including Moderna, which is using the same technology it used to rapidly develop a Covid vaccine. Is a virus we all have causing multiple sclerosis? 2022-04-13T04:00:00Z EBV can behave differently in children — adolescents and young adults may develop infectious mononucleosis — so the conclusions of the Harvard study might not be applicable to those infected when very young, she said. Multiple sclerosis and commonly found Epstein-Barr virus likely to be linked, major study says 2022-01-14T05:00:00Z His research follows up a theory11 that vitamin D may boost immune responses to EBV and, conversely, that a lack of vitamin D may lead to poor responses to EBV. Aetiology: Neighbourhood watch : Nature : Nature Research 2016-11-29T05:00:00Z Some researchers suspect EBV transforms B cells so they become pathogenic; others, including Steinman, suggest an EBV protein resembles a neural protein and teaches the immune system to attack nerves. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z EBV infection is a life long, dynamic infection that is usually kept in check by the immune system in healthy people. Building a better lymphoma vaccine 2018-11-13T05:00:00Z Therapies that target B cells that have been infected with EBV - and drugs that attack the virus itself - are also being investigated. Is a virus we all have causing multiple sclerosis? 2022-04-13T04:00:00Z He noted that EBV’s relatively mild symptoms meant there had been little interest in preventing it, and there is no vaccine for the virus. Multiple sclerosis and commonly found Epstein-Barr virus likely to be linked, major study says 2022-01-14T05:00:00Z Røsjø says that this study was the first indication of an interaction between vitamin D and EBV. Aetiology: Neighbourhood watch : Nature : Nature Research 2016-11-29T05:00:00Z An EBV vaccine could help researchers prove the virus has a causal role by vaccinating a large cohort of young people at high risk for MS because of family history. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z His team is looking at other EBV surface proteins in addition to gp350, including ones that the virus uses to invade epithelial cells. Building a better lymphoma vaccine 2018-11-13T05:00:00Z Once you get EBV, you are stuck with it in your body for life - as it takes up residence in those antibody-making B cells. Is a virus we all have causing multiple sclerosis? 2022-04-13T04:00:00Z As part of the study, the researchers examined 123 people who had neither MS nor EBV when their blood samples were first taken. Multiple sclerosis and commonly found Epstein-Barr virus likely to be linked, major study says 2022-01-14T05:00:00Z Perhaps EBV causes such an imbalance in MS by activating the B cells that they no longer perform their crucial regulatory functions, but instead start to promote inflammation. Aetiology: Neighbourhood watch : Nature : Nature Research 2016-11-29T05:00:00Z Several years ago, GlaxoSmithKline developed a vaccine based on an EBV envelope protein but abandoned it after a trial showed it reduced the incidence of mono but didn’t prevent EBV infections. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z Studies of immunosuppressed transplant patients show that the higher the level of EBV in their blood, the higher their chances of developing an EBV lymphoma. Building a better lymphoma vaccine 2018-11-13T05:00:00Z EBV has been on the list of suspects for MS for decades, but definitive proof has been hard to gather because the virus is so common and multiple sclerosis is so rare. Is a virus we all have causing multiple sclerosis? 2022-04-13T04:00:00Z Immigration Minister Scott Morrison: "These measures include temporarily suspending our immigration programme... from EBV affected countries" Australia's Ebola visa ban condemned 2014-10-28T04:00:00Z The distribution of histological subtypes of gastric cancer and the frequencies of H. pylori and EBV associated gastric cancer vary across the globe5. Comprehensive molecular characterization of gastric adenocarcinoma : Nature : Nature Publishing Group 2014-07-22T04:00:00Z Another from Moderna contains messenger RNA that instructs cells to make four different EBV proteins. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z The trouble is, EBV is adept at flying under the radar. Building a better lymphoma vaccine 2018-11-13T05:00:00Z A team at Harvard University went looking through samples from 10 million people to establish the connection between EBV and multiple sclerosis. Is a virus we all have causing multiple sclerosis? 2022-04-13T04:00:00Z Stalwart investigators continued to track EBV until the viral culprit was declared a class I carcinogen by the International Agency for Research on Cancer and the World Health Organization in the late 1990s. [Perspective] Epstein-Barr Virus Turns 50 2014-03-20T18:25:37.322Z Historically, Velasquez-Manoff explains, the transfer of saliva from parents to infants was a key mechanism for exposing young babies to EBV during the optimal window of immunological tolerance: that is, before age 2. Should You Pre-Chew Your Baby's Food? 2013-05-21T21:11:00Z Vaccine expert Larry Corey of the Fred Hutchinson Cancer Research Center cautions that despite the potential public health benefits, there’s no guarantee a company will take an EBV vaccine through licensing. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z Here, scientists extract immune cells from people with cancer, stoke them with EBV proteins and grow armies of responsive immune cells in the lab, before transfusing them back into patients. Building a better lymphoma vaccine 2018-11-13T05:00:00Z The study authors hope it will spur the development of a vaccine against EBV. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z Despite the consensus that EBV is a bona fide tumor virus, the mechanisms of cancer causation by EBV remain an area of active investigation and controversy 50 years since its initial discovery. [Perspective] Epstein-Barr Virus Turns 50 2014-03-20T18:25:37.322Z But EBV is often asymptomatic when contracted by babies – or it may simply result in one of the generic runny nose/low-grade fever episodes that characterize a normal winter season. Should You Pre-Chew Your Baby's Food? 2013-05-21T21:11:00Z Still, the new evidence firming up the role of EBV in MS “should make the risk benefit of that investment much greater,” he says. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z Balfour, for example, set up the Mono Project at the University of Minnesota partly to drive forward research, but also, he says, to raise awareness of EBV and glandular fever. Building a better lymphoma vaccine 2018-11-13T05:00:00Z Researchers then want to test whether vaccinating young people against EBV prevents MS. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z Of the 801 with sufficient blood samples, 35 were negative for EBV in their first blood test; all but one became EBV positive during the study before developing MS on average 5 years later. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z The disappearance of premastication as a feeding practice during weaning, he suggests, may be partially responsible for the later age of EBV exposure in Western countries compared to historical norms. Should You Pre-Chew Your Baby's Food? 2013-05-21T21:11:00Z The work leaves many questions, such as why MS only affects about one in 1000 people even though nearly everyone will contract EBV in their lifetime. Two decades of soldiers’ medical records implicate common virus in multiple sclerosis 2022-01-12T05:00:00Z And Cohen thinks there is a need for more epidemiological studies to gain a better idea of the economic burden of EBV. Building a better lymphoma vaccine 2018-11-13T05:00:00Z |
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