| 单词 | DNA polymerase |
| 例句 | There is a recursion here that is worth noting: like all proteins, DNA polymerase, the enzyme that enables DNA to replicate, is itself the product of a gene.* The Gene 2016-06-02T00:00:00Z DNA replication requires many more proteins than just DNA polymerase to unfold the twisted double helix and to ensure that the genetic information is copied accurately. The Gene 2016-06-02T00:00:00Z Mutations might occur during replication if the enzyme DNA polymerase makes a mistake. Cosmos 1980-01-01T00:00:00Z Once the unwinding is under way, a remarkable enzyme called DNA polymerase helps ensure that the copying works almost perfectly. Cosmos 1980-01-01T00:00:00Z Why did the chromosome blush when the DNA polymerase* came into the room? Style Invitational Week 1168: Asterisky business — give us nerdy humor 2016-03-24T04:00:00Z PCR uses a special form of DNA polymerase, the enzyme that replicates DNA, and other short nucleotide sequences called primers that base pair to a specific portion of the DNA being replicated. Concepts of Biology 2013-04-25T00:00:00Z DNA polymerase reads the template strand in the 3’ to 5’ direction and adds nucleotides only in the 5’ to 3’ direction. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase, or the main enzyme involved in DNA replication, joins nucleotides to synthesize a new complementary strand of DNA. Miller & Levine Biology 2018-01-01T00:00:00Z DNA polymerase brings in the correct bases to complement the template strand, synthesizing a new strand base by base. Anatomy and Physiology 2013-06-19T00:00:00Z This technique, developed in the 1980s, uses the ability of DNA polymerase chains to synthesize new strands and make billions of copies of the sequences that are unique to the virus. Frequent testing could not insulate the president from the coronavirus 2020-10-02T04:00:00Z Figure 10.4 Polymerase chain reaction, or PCR, is used to produce many copies of a specific sequence of DNA using a special form of DNA polymerase. Concepts of Biology 2013-04-25T00:00:00Z DNA unwinds, transcription factors bind, the termination complex forms, and DNA polymerase adds nucleotides to the mRNA. Biology for AP Courses 2022-06-09T00:00:00Z Then an enzyme called DNA polymerase creates the bonds connecting nucleotides, and ensures that each new strand is an exact copy of its original. Miller & Levine Biology 2018-01-01T00:00:00Z A DNA polymerase is an enzyme that adds free nucleotides to the end of a chain of DNA, making a new double strand. Anatomy and Physiology 2013-06-19T00:00:00Z Using ϕ29 DNA polymerase proved to be much more efficient: the technique was called multiple displacement amplification. Margarita Salas (1938–2019) 2019-12-05T05:00:00Z During elongation, an enzyme called DNA polymerase adds DNA nucleotides to the 3' end of the template. Concepts of Biology 2013-04-25T00:00:00Z One of the key players is the enzyme DNA polymerase, also known as DNA pol, which adds nucleotides one by one to the growing DNA chain that are complementary to the template strand. Biology for AP Courses 2022-06-09T00:00:00Z For example, when you studied DNA replication, you learned about the enzyme DNA polymerase. Miller & Levine Biology 2018-01-01T00:00:00Z Replication of the Leading Strand is very straightforward, with the DNA polymerase enzyme copying from the purple template strand to form the new DNA strand, shown in orange. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z Kording is part of a team trying to do this by exploiting DNA polymerase, the enzyme that cells use to build DNA from its component bases. Neuroscience: Solving the brain 2013-07-17T17:20:30.610Z Because DNA polymerase can only add new nucleotides at the end of a backbone, a primer sequence, which provides this starting point, is added with complementary RNA nucleotides. Concepts of Biology 2013-04-25T00:00:00Z DNA polymerase can only extend in the 5' to 3' direction, which poses a slight problem at the replication fork. Biology for AP Courses 2022-06-09T00:00:00Z The next candidate to be considered was DNA polymerase, an enzyme that promotes the incorporation of precursor substances into new DNA in a way that is specified by the composition of the preexisting "template" DNA. Transplanted Nuclei and Cell Differentiation, by Sir John B. Gurdon 2012-10-09T23:45:00.177Z The RNA primers are now removed, and the gaps are filled in by DNA polymerase to form a complete replicate of the lagging strand. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z He and his colleagues have designed a synthetic DNA polymerase that, when surrounded by high levels of calcium, inserts the wrong base into the artificial DNA strand it constructs. Neuroscience: Solving the brain 2013-07-17T17:20:30.610Z As you have learned, the DNA polymerase enzyme can add nucleotides in only one direction. Concepts of Biology 2013-04-25T00:00:00Z A protein called the sliding clamp holds the DNA polymerase in place as it continues to add nucleotides. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase activity in living cells has been tested by introducing purified DNA and tritium-labeled thymidine into eggs. Transplanted Nuclei and Cell Differentiation, by Sir John B. Gurdon 2012-10-09T23:45:00.177Z This directionality matters because DNA replication takes place under the direction of an enzyme known as DNA polymerase. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z In the wells in which the sensor detects a hydrogen ion, the ion shows that the DNA that the DNA polymerase added an A to its growing strand. A $1000 Genome by 2013? 2011-07-20T21:35:09Z Once the lagging strand template is sufficiently elongated, DNA polymerase can now add nucleotides that are complementary to the ends of the chromosomes. Concepts of Biology 2013-04-25T00:00:00Z Once the 3' end of the lagging strand template is sufficiently elongated, DNA polymerase can add the nucleotides complementary to the ends of the chromosomes. Biology for AP Courses 2022-06-09T00:00:00Z This means that the cytoplasmic factor in ducing DNA synthesis in eggs includes DNA polymerase or something that ac tivates this enzyme. Transplanted Nuclei and Cell Differentiation, by Sir John B. Gurdon 2012-10-09T23:45:00.177Z DNA polymerase is now able to use these RNA fragments as a starting point to synthesize complementary fragments of DNA in between the RNA fragments. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z Sequencing primers and DNA polymerase are then bound to the templates and pipetted into the chip’s loading port. An integrated semiconductor device enabling non-optical genome sequencing 2011-07-20T17:20:42.953Z Because DNA polymerase can only synthesize DNA in a 5' to 3' direction, the other new strand is put together in short pieces called Okazaki fragments. Concepts of Biology 2013-04-25T00:00:00Z DNA replication is a highly accurate process, but mistakes can occasionally occur, such as a DNA polymerase inserting a wrong base. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase reads the template strand in the 5’ to 3’ direction and adds nucleotides only in the 3’ to 5’ direction. Biology for AP Courses 2022-06-09T00:00:00Z This new strand is formed in the 5' to 3' direction, since DNA polymerase only works in that direction. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z Primase synthesizes RNA primer which is used by DNA polymerase to form a daughter strand. Biology for AP Courses 2022-06-09T00:00:00Z Primase synthesizes an RNA primer to initiate synthesis by DNA polymerase, which can add nucleotides in only one direction. Concepts of Biology 2013-04-25T00:00:00Z Thus, DNA polymerase is able to remove the wrongly incorporated bases from the newly synthesized, non- methylated strand. Biology for AP Courses 2022-06-09T00:00:00Z Primase synthesizes RNA primer which is used by DNA polymerase to form a daughter strand. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase is now able to use these short RNA fragments as a starting point to synthesize DNA between the RNA gaps, shown in orange. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z Primase synthesizes DNA primer which is used by DNA polymerase to form a daughter strand. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase I removes the RNA primers from the developing copy of DNA. Biology for AP Courses 2022-06-09T00:00:00Z Primase synthesizes an RNA primer to initiate synthesis by DNA polymerase, which can add nucleotides only in the 5' to 3' direction. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase I seals the ends of the new segment, especially the Okazaki fragments. Biology for AP Courses 2022-06-09T00:00:00Z This solves the directionality problem of DNA polymerase, but now we run into another problem, known as the end replication problem. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z A primer, DNA polymerase and all four nucleotides are added. Biology for AP Courses 2022-06-09T00:00:00Z A primer, DNA polymerase and all four nucleotides are added. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase can then extend the DNA using the primer. Biology for AP Courses 2022-06-09T00:00:00Z The DNA can be replicated by the DNA polymerase enzyme. Biology for AP Courses 2022-06-09T00:00:00Z Although the basis for each of these different DNA polymerase molecules is the same, each one has been adapted to function in the organism’s environmental niche. Biology for AP Courses 2022-06-09T00:00:00Z A primer is required to initiate synthesis, which is then extended by DNA polymerase as it adds nucleotides one by one to the growing chain. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase I adds the RNA primers to the already developing copy of DNA. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase reads the template strand in the 3’ to 5’ direction and adds nucleotides only in the 5’ to 3’ direction. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase I removes the enzyme primase from the developing copy of DNA. Biology for AP Courses 2022-06-09T00:00:00Z The enzyme primase synthesizes RNA primers to initiate DNA synthesis by DNA polymerase, which can add nucleotides only in the 5' to 3' direction. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase recognizes the 3'-OH end as its landing site; thus, polymerase “reads” the template strand in the 3' to 5' direction and builds the complementary DNA polymer in the 5' to 3' direction. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase starts adding nucleotides to the 3'-OH end of the primer. Biology for AP Courses 2022-06-09T00:00:00Z DNA polymerase reads the template strand in the 5’ to 3’ direction and adds nucleotides only in the 5’ to 3’ direction. Biology for AP Courses 2022-06-09T00:00:00Z A primer, DNA polymerase and all four nucleotides are added. Biology for AP Courses 2022-06-09T00:00:00Z For example, all organisms use DNA polymerase to replicate their genomes. Biology for AP Courses 2022-06-09T00:00:00Z |
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