| 单词 | differentiation |
| 例句 | Newton’s method of differentiation was based on a notational trick: he let the fluxions change, but he only let them change infinitesimally. Zero: The Biography of a Dangerous Idea 2000-02-07T00:00:00Z Newton’s style of differentiation was based upon fluxions—the flows—of mathematical expressions that he called fluents. Zero: The Biography of a Dangerous Idea 2000-02-07T00:00:00Z They are generally speaking as mistrustful of wizards as they are of Muggles and indeed seem to make little differentiation between us. Fantastic Beasts and Where to Find Them 2001-01-01T00:00:00Z Study after study around the world has shown that singing enables infants to train their brains and memories, to recognise pitch differentiation as a preparation for the full development of spatial awareness. The Story of Music 2012-12-25T00:00:00Z This process, the first half of calculus, is now known as differentiation; however, Newton's method of differentiation doesn't look very much like the one we use today. Zero: The Biography of a Dangerous Idea 2000-02-07T00:00:00Z There was frequently some element of truth in these essential lines of differentiation. The Boys in the Boat: Nine Americans and Their Epic Quest for Gold at the 1936 Berlin Olympics 2014-05-27T00:00:00Z Calculus is the combination of these two tools, differentiation and integration, in one package. Zero: The Biography of a Dangerous Idea 2000-02-07T00:00:00Z It’s alarming to discover — or remember — that the same popped-eyes and smacked lips Mr. Cosby used to delight children has previously been used, without much differentiation at all, to pursue women for sex. How to Think About Bill Cosby and ‘The Cosby Show’ 2017-06-18T04:00:00Z I think that’s where a new Chinese brand needs to be if it wants to claim some differentiation and build its own legitimacy. Special Report: A Cut Above: Watches: A Huge Market, With New Players 2011-03-24T07:01:13Z It would allow no differentiation and qualification, treating the site almost as if it were the Slave Market of Charleston. Critic?s Notebook: To Each His Own Museum, as Identity Goes on Display 2010-12-28T23:04:19Z There was some differentiation in clothing between Romans and Egyptians but the politics of this work, first seen at London's Haymarket theatre in 1724, remained vague. Julius Caesar; Siegfried – review 2012-10-06T23:08:03Z Those offerings are one component of what drives competition and product differentiation among airlines. Airplanes’ space wars are shifting to the human rights front 2015-09-17T04:00:00Z As elsewhere in the Bible, each verse of the psalm is a self-contained unit, often consisting of a single sentence, and the careful differentiation of comma, semi-colon and colon informs both sound and sense. Poem of the week: Psalm 23 2011-02-07T10:26:09Z When he would get on the floor, I would get on the floor with him, and it was a perspective and a height differentiation that was sort of infantilizing. Jake Gyllenhaal on Ambivalent Heroes and, Um, Perms 2018-01-11T05:00:00Z But in Champagne, such differentiation represents almost a sort of heresy against the art of blending. Champagne Seeks to Discover Itself in Single-Vineyard Wines 2017-12-21T05:00:00Z Much of what he looks for in acquisitions is obvious: a good product, differentiation, a solid, scalable supply chain. The Great Amazon Flip-a-Thon 2021-03-17T04:00:00Z There was never any differentiation of male or female roles, whether it be gender characteristics or a job to be done. Danny DeVito: I still miss my father 2012-06-15T23:05:18Z But "Expendables 3" arrives as the third such movie in four years, without much development or differentiation in the story lines, directorial vision or overall ambition. 'The Expendables 3' tanks at the box office: 5 things that went wrong 2014-08-18T04:00:00Z I especially liked the differentiation of instrumental voices: this was a living, moving Bruckner, not a faceless monument. A Hell-Raising Mezzo-Soprano Cuts Through a Dreary First Week at the Metropolitan Opera 2018-10-04T04:00:00Z “There appears to be a differentiation between national politics and people, which is quite uplifting and entirely in the spirit of the event,” she said. Eurovision 2017: UK gets excuses in early but is tipped to avoid nul points 2017-05-13T04:00:00Z In purely narrative terms, though, there's not enough visual differentiation between Jews and Babylonians for consistent clarity. Nabucco – review 2013-04-01T16:56:01Z “There’s no differentiation of my pay scale and the dance artist newbie that just walked onto the scene, just moved to L.A. a couple months ago, and this is her first job,” she said. What Do Dancers Bring to a Halftime Show? They Complete the Picture. 2022-01-28T05:00:00Z Guitars, often with only slight differentiation, appear in Malta, New Zealand, Argentina and the American Southwest. Museum Review: The Musical Instrument Museum Opens in Phoenix 2010-04-24T00:46:00Z That differentiation has happened perhaps more in the last 30 years than in any other time in human history. Doomed to relive high school? Science that says who we were at 16 still defines us 2017-06-04T04:00:00Z Still, this concerto requires differentiation between the many allusions and influences that Shostakovich crams together. Osmo Vanska Conducts the Mostly Mozart Festival Orchestra 2014-08-10T04:00:00Z As an additional differentiation, Dr. Reddy's is increasing its focus on biogenerics, an area not many large companies are focusing on. Dr. Reddy's Rejuvenation 2011-02-03T23:00:00Z “We wanted to be at a point of differentiation.” Great Oregon Wines Beyond the Willamette Valley 2021-09-17T04:00:00Z Clad in uniformly dun-colored garb, with little differentiation and definition among them, they also seem oddly generic, at least in appearance. A puppet version of Jane Austen's 'Northanger Abbey' is modest success 2014-12-09T05:00:00Z They would avoid discussing race out of a sincere ethical desire to wash the stain of racial differentiation from our nation. “Get Out” and the Death of White Racial Innocence 2017-03-27T04:00:00Z In general, the guidelines, including the differentiation between states in Mexico, for example, are a reflection of the restrictions that United States government personnel in the country adhere to. New Country Rankings Aim to Help Travelers Choose Safe Destinations 2018-01-19T05:00:00Z But there’s ample differentiation across the Electric Zoo schedule, especially with five stages running this year. | Pop: Microcultures on the Island 2013-08-23T17:55:05Z I grew up calling it "Mom's Pizza": an important differentiation, cravings-wise, from the rare occasion we got pizza takeout. The crispy-cheesy legend of Mimi's pizza 2021-02-08T05:00:00Z Italian soprano Patrizia Ciofi sounds a little faded and not exactly effortless on the many vocal acrobatics, but she brings a dramatic differentiation of vocal colors to the innocent girl Dinorah. CD reviews: Eschenbach and Goerne take on somber Brahms 2016-08-03T04:00:00Z The necessity of this slap, however, rests in the differentiation between recognizing what a joke is, which is it has a beginning and a middle, and defining story, which has a beginning, middle and end. Hannah Gadsby’s “Nanette” and the case for quitting comedy 2018-07-03T04:00:00Z I would say certainly in the last 100 years there has been more the differentiation between using it to refer to something more like “of the populace” than now using it to mean “a celebrity.” Doomed to relive high school? Science that says who we were at 16 still defines us 2017-06-04T04:00:00Z The differentiation between the two time frames came in part from using different kinds of camera lenses. ‘It’s a Labyrinth’: A Meta Detective Story Comes to the Screen 2022-10-13T04:00:00Z True to the improvisatory nature of the genre, Gewirtzman opened with a brassy, off-the-cuff approach but switched to a more refined differentiation of voicing in the fugal sections. A young virtuoso makes his D.C. debut 2015-11-10T05:00:00Z "They may be the only tools at the disposal of Pakistani society to stem the rising tide of hate, religious intolerance and ethnic differentiation," said Yusuf. Pakistan bans film featuring Indian James Bond 2012-03-26T09:16:04Z A lot of the differentiation is in the marketing: emotional appeals, headlines and external promotion. GoFundMe Confronts Coronavirus Demand 2020-03-26T04:00:00Z Though this goes against the current trend for brand consolidations, as espoused by Burberry and Zegna, Mr. Grieder said the differentiation would help Hugo Boss stand out. Can Hugo Boss Actually Be Cool? 2022-01-26T05:00:00Z But Rushford revels in finding minute differentiations of expression within the general climate of calm. 7 Things to Do This Weekend 2020-10-22T04:00:00Z “People want differentiation, and they want to experience a place,” said Chad Cuddy, general manager of the new dual Hyatt in Denver. At Budget Hotels, Local Flavor Is Now Included 2016-02-23T05:00:00Z Without that feeling of specificity and differentiation, the movement blurs into sequential torpor. Dance Review: Movements in the Cunningham Mode 2011-04-29T21:20:53Z The problems include no differentiation, classroom favoritism, poorly thought-out assignments, student work not returned or returned without comments or grading, and a teacher who texts during class. Motherlode Blog: How to Approach a Difficult Conversation 2014-01-30T20:12:30Z Dear Heloise: There can be some confusion when making the "o" and "zero" differentiation. Perspective | Hints From Heloise: Rummaging through some hints 2018-07-16T04:00:00Z There is little differentiation between the various vocal lines, and no real acting to be done. Music Review: A von Trier Tragedy, Recast as Opera 2011-07-31T21:40:49Z Now, I'm a little more relaxed about the differentiation between when and how to use a blender versus a food processor. How a $20 food processor made me a better weeknight cook 2023-03-11T05:00:00Z "In everything from wedding to portrait to commercial photography, young professionals are finding digital so prevalent that they're looking for a sense of differentiation," says Kayce Baker, a marketing director at Fujifilm North America. How much longer can photographic film hold on? 2011-05-30T21:16:07Z Skirts got ever larger, suits evermore unbound, gender differentiation increasingly irrelevant and the definition of just who got to send a message with what they wore ever more expansive. The Year on the Red Carpet 2021-12-08T05:00:00Z Schilling would eventually like to make a variety of chocolate bars using cacao beans from a single valley in each one so that you can “taste the differentiation of terroir.” T Magazine: Bali Wood 2011-11-15T14:00:04Z The other differentiation between the two, and something that sets Vimeo apart from every other streaming service, is that it is not subscription-based. Vimeo launches new originals and offers 'high-quality' alternative to YouTube 2016-03-10T05:00:00Z There's a rich, complex differentiation in the further-cooked oven sauce, which has a sharper flavor and often a darker color. How to avoid the 8 most common sheet pan mistakes 2023-02-04T05:00:00Z “We are showing the differentiation of the amount of cases in Africa ever since the U.S. started to educate people there,” Stephanie said. Helen Gurley Brown Scholars Redefine ‘Cosmo Girl’ 2015-07-29T04:00:00Z There is not enough differentiation of musical character, which dulls the dramatic richness and intensity, despite the pulsing, incisive performance that the conductor Titus Engel draws from the orchestra. Music Review: Lyrical Cowboys In Love, On Stage 2014-01-29T09:33:49Z Bicknell & Co. and “The American Builder’s Companion” by Asher Benjamin — that show historical precedence, proportions, molding shape used during specific eras, and style differentiation between, say, Victorian gingerbread and gothic revival. 7 mistakes homeowners make when renovating older properties 2018-11-05T05:00:00Z “There was no stage, no differentiation between the band and the crowd. It was just one big steamy ball of energy.” Lost punk record from Duff McKagan, Mother Love Bone drummer surfaces after nearly 40 years 2021-04-12T04:00:00Z But this differentiation is more formal than character defining or dancer revealing. Review: City Ballet Holds Steady as an Old Guard Meets the New 2023-05-05T04:00:00Z In some industries with little or no product differentiation, processes like advertising or merchandising may be more critical. Who's Running General Motors? 2010-03-26T17:00:00Z By contrast, Janáček’s Idyll for String Orchestra, a superficially appealing but callow rarity, went on too long and was performed with too little differentiation to generate real enthusiasm. The future is not here: Two 21st-century chamber ensembles in D.C. 2015-04-13T04:00:00Z “I think tactically it’s similar but the kind of creators we have and the kind YouTube has is where the differentiation comes from,” Toles says. Vimeo launches new originals and offers 'high-quality' alternative to YouTube 2016-03-10T05:00:00Z “I think the Chinese will never be fully assimilated as long as there is physical identity or physical differentiation,” she said. Betty Lee Sung, Scholar of Chinese in America, Dies at 98 2023-01-20T05:00:00Z Dr. Refardt sums up: "In view of these results, we recommend the salt infusion test as the gold standard for reliable differentiation between polydipsia and vasopressin deficiency." Excessive fluid consumption: Habit or hormonal disorder? 2023-11-16T05:00:00Z Scientists from St. Jude Children's Research Hospital comprehensively examined the transcription factors involved in T-cell differentiation states in cancer. Scientists identify T-cell differentiation nodes to improve cancer-killing 2023-11-15T05:00:00Z The researchers take stem cells from a single patient's blood and chemically wind them back in time, then forward again in a process called "directed differentiation," to eventually become insulin-producing cells. A step closer to injection-free diabetes care: Innovation in insulin-producing cells 2023-11-06T05:00:00Z It also revealed new insights into which parts of cat DNA are most likely to evolve rapidly and how they play a role in species differentiation. New secrets about cat evolution revealed 2023-11-02T04:00:00Z The differentiation strategy, meanwhile, placed a greater emphasis on factors such as demand conditions and professionals. What’s in a name? U.S. dominates, Russia plunges in national ‘brand’ rankings 2023-10-27T04:00:00Z "We were able to quantify cellular proliferation and differentiation rates of many cell types across the entire brain in a single experiment, which wasn't possible using conventional approaches," Cao says. New method tracks how brain cells age 2023-10-26T04:00:00Z They then used this information to enhance anticancer activity in preclinical models by promoting or blocking T-cell differentiation. Scientists identify T-cell differentiation nodes to improve cancer-killing 2023-11-15T05:00:00Z The other possibility is that “this becomes a moment of differentiation” separating the qualities of the various robotaxi companies in the eyes regulators and the general public. A Cruise car hit a pedestrian. The company's response could set back California's new robotaxi industry 2023-10-26T04:00:00Z The new study shows that this adaptive shift followed feeding niche differentiation and the global decline of other predatory marine reptiles over 170 million years ago. Ancient sea monster remains reveal oldest mega-predatory pliosaur 2023-10-20T04:00:00Z Aptamers are single-stranded pieces of DNA that bind to target proteins and are able to modulate signaling cascades during cell differentiation when a stem cell commits to a specific functional role or phenotype. DNA aptamer finds novel application in regulating cell differentiation 2023-10-10T04:00:00Z "In lakritz, all types of neuronal cells formed at the right place and numbers, only the speed of differentiation was slightly off." Vision in the brain: Hardwired for action 2023-09-28T04:00:00Z The scientists showed they could precisely interrupt the flow of the differentiation process, thereby enhancing antitumor efficacy. Scientists identify T-cell differentiation nodes to improve cancer-killing 2023-11-15T05:00:00Z With their new sensitive method, the researchers can follow microRNA targeting of thousands of RNAs during biological processes such as the cell cycle or differentiation into red blood cells. Researchers develop first method to study microRNA activity in single cells 2023-09-21T04:00:00Z “I feel we are in a huge hole with our games lineup both for platform marketing/differentiation and our Gamepass content,” Spencer wrote. Microsoft Gaming CEO discussed Nintendo acquisition, Xbox woes in leaked emails 2023-09-22T04:00:00Z The team set out to definitively investigate whether the evolution of enhanced colour visual system in some primates that allows the differentiation of red from green has facilitated the evolution of red colour traits. Colorful primates don't have better color vision, study finds 2023-09-22T04:00:00Z These findings help to better understand cell differentiation and could thus be a basis for future developments in the field of targeted culturing of tissue in cell replacement therapies. Career choice in stem cells: Predetermined or self-selected? 2023-09-19T04:00:00Z T-cell differentiation is conceptually similar to a river running down a mountain. Scientists identify T-cell differentiation nodes to improve cancer-killing 2023-11-15T05:00:00Z Although Eritreans supporting the regime would not appear to be in need of international protection as refugees, the authorities in Israel have not made differentiations between asylum seekers based on their political affiliations until now. Israel: Netanyahu wants immediate deportation of Eritreans after Tel Aviv violence 2023-09-03T04:00:00Z As a result, he’s seen growth and survival problems in the fish larvae and embryos he uses to study differentiation in neural cells. In Uruguay, a water crisis is upending research 2023-08-17T04:00:00Z Everywhere you go, you get that differentiation that you speak of, where everything looks the same. Are humans a cancer on the planet? A physician argues that civilization is truly carcinogenic 2023-08-05T04:00:00Z "Our research contributes to a better understanding of the process itself and the key players involved in cell differentiation," explains Christian Schröter. Career choice in stem cells: Predetermined or self-selected? 2023-09-19T04:00:00Z Their work showed which individual transcription factors and their networks are responsible for each T cell differentiation state, providing targets for improving immunotherapy. Scientists identify T-cell differentiation nodes to improve cancer-killing 2023-11-15T05:00:00Z “You just end up playing catch up unless you have some major differentiator. And in this business there’s just not a lot of differentiation. Most of it’s about scale,” Hoium said. Can Bartell store closures relief some of Rite Aid headaches? 2023-06-29T04:00:00Z The differentiation came from designing collections that fit to a market or a demographic and their needs. Modernist designer Paul McCobb is having a moment. Now you can tour a house full of his work 2023-05-23T04:00:00Z This differentiation and specialization of tissues is part of what allows for such incredible animal diversity. Fundamentals of Biology 2015-01-01T00:00:00Z Increasing exchange between Neolithic cultures and the prominence of war may also have led to greater social differentiation. World History: to 1500 2023-04-19T00:00:00Z By examining an individual T cell's gene expression pattern, the researchers could compare them to see which knocked-out transcription factors most affected T-cell differentiation and anticancer activity. Scientists identify T-cell differentiation nodes to improve cancer-killing 2023-11-15T05:00:00Z Organs develop from the germ layers through the process of differentiation. Concepts of Biology 2013-04-25T00:00:00Z This directly undermines markets, avoiding price wars through efforts at often-meaningless product differentiation through massive advertising, which is itself dedicated to undermining markets in the official sense, based on informed consumers making rational choices…. The corporate attack on democracy 2023-04-24T04:00:00Z As plant cells grow, they also become specialized into different cell types through cellular differentiation. Fundamentals of Biology 2015-01-01T00:00:00Z Evidence from the few discovered burial sites dating to around 2000 BCE supports the suggestion that wealth contributed to social differentiation even then. World History: to 1500 2023-04-19T00:00:00Z While the government charges different interest rates depending on the loan type, within those loan types there is no differentiation. Say Hi to SoFi. It’s Suing to Force You to Repay Student Loans Faster. 2023-04-22T04:00:00Z During differentiation, the embryonic stem cells express specific sets of genes that will determine their ultimate cell type. Concepts of Biology 2013-04-25T00:00:00Z "The differentiation really comes down to technology and services," he said. Ford must rethink its brand for China as EVs boom, CEO says 2023-04-21T04:00:00Z True secretory alveoli only develop in pregnancy, where rising levels of estrogen and progesterone cause further branching and differentiation of the duct cells, together with an increase in adipose tissue and a richer blood flow. Fundamentals of Biology 2015-01-01T00:00:00Z There was clearly some degree of differentiation within them. World History: to 1500 2023-04-19T00:00:00Z Yet a differentiation should be made between private equity and other financial outfits owning large numbers of properties as investments, and ordinary landlords who live off the rents on one or two houses. The battle is on to increase housing supply; we’ll see if it works 2023-03-03T05:00:00Z The process of differentiation is regulated by location-specific chemical signals from the cell’s embryonic environment that sets in play a cascade of events that regulates gene expression. Concepts of Biology 2013-04-25T00:00:00Z Even when the narrative splits into parallel tracks, there’s precious little differentiation or modulation from one scene to the next. Review: The Marvel machine hits a new low with 'Ant-Man and the Wasp: Quantumania' 2023-02-14T05:00:00Z Their other top picks included inflation-linked bonds to shield against price rises and selective exposure to corporate credit, as higher interest rates restore some differentiation in company bond spreads. Analysis: Global hedge funds plan 2023 around inflation risk 2023-01-04T05:00:00Z "But for platforms that mix own offerings and third-party offerings, they should consider - from a trade mark perspective - whether they want to create a different look and feel, or other clear differentiations." Amazon could be blamed for fake Louboutin shoe ads - EU 2022-12-22T05:00:00Z "We need specificity, objectivity and differentiation as investors," said Andrew Howard, global head of sustainable investment at British fund manager Schroders. China urges action as ministers meet at U.N. nature summit 2022-12-15T05:00:00Z "The patterns of genetic diversity and differentiation observed in worldwide random-bred cats parallel those of other species, especially humans once they became farmers, suggesting human history is written in the DNA of domesticated species." How the evolution of domestic cats traces the history of colonization 2022-12-14T05:00:00Z Under a March 2019 formal agreement, both agencies agreed to a joint regulatory framework wherein the FDA oversees cell collection, cell banks and cell growth and differentiation. Lab-grown meat is safe to eat, says FDA 2022-11-16T05:00:00Z Dispensing with the newspaper's differentiation between "deniers" and "skeptics," socialist writer Ashley Smith summarized the development as follows: "Two hundred deranged reactionaries elected to government." 210+ GOP candidates who spread doubt and lies about 2020 election won power in the midterms 2022-11-09T05:00:00Z His advice was simple: Look for as many specifics as possible, including time frames for increasing activity, benchmarks against which increases can be measured, and clear differentiations between charity and business. Where $30 Billion to Fix Systemic Racism Actually Goes 2022-10-21T04:00:00Z He also called the differentiation of so-called feminine and masculine traits as "total scientific absurdity". Hungarians warning education becoming 'too feminine'- report 2022-08-26T04:00:00Z Cytokinins are known to delay senescence in leaf tissues, promote mitosis, and stimulate differentiation of the meristem in shoots and roots. Biology for AP Courses 2022-06-09T00:00:00Z Yet Callisto seems to have frozen solid before the process of differentiation was complete. Astronomy 2016-10-13T00:00:00Z For example, the word Eskimo is a European term used to describe people living in the Arctic without regard for differentiation. Writing Guide 2021-12-21T00:00:00Z At the time of the changes, the government argued that the new scale "recognises more clearly the achievements of high-attaining students, as the additional grades allow for greater differentiation". GCSEs 2022: The 9-1 grading system explained 2022-07-25T04:00:00Z Do the rules of differentiation apply in this context? Calculus, Volume 3 2016-03-30T00:00:00Z B. During development, cell differentiation occurs, and the expression of genes is permanently switched off. Biology for AP Courses 2022-06-09T00:00:00Z The separation of Earth into layers of different densities is an example of differentiation, the process of sorting the major components of a planet by density. Astronomy 2016-10-13T00:00:00Z Evaluating the derivative and indefinite integral in this way is called term-by-term differentiation of a power series and term-by-term integration of a power series, respectively. Calculus, Vol 2 2016-03-30T00:00:00Z The process of finding a derivative is called differentiation. Calculus, Volume 1 2016-03-30T00:00:00Z In single-variable calculus, we found that one of the most useful differentiation rules is the chain rule, which allows us to find the derivative of the composition of two functions. Calculus, Volume 3 2016-03-30T00:00:00Z Before activation and differentiation, B cells can also function as APCs. Biology for AP Courses 2022-06-09T00:00:00Z In addition to the M-type asteroids, a few other asteroids show signs of early heating and differentiation. Astronomy 2016-10-13T00:00:00Z First, we state Term-by-Term Differentiation and Integration for Power Series, which provides the main result regarding differentiation and integration of power series. Calculus, Vol 2 2016-03-30T00:00:00Z At this point, by combining the differentiation rules, we may find the derivatives of any polynomial or rational function. Calculus, Volume 1 2016-03-30T00:00:00Z To calculate a partial derivative with respect to a given variable, treat all the other variables as constants and use the usual differentiation rules. Calculus, Volume 3 2016-03-30T00:00:00Z During differentiation, the embryonic stem cells express specific sets of genes which will determine their ultimate cell type. Biology for AP Courses 2022-06-09T00:00:00Z Accretion of infalling materials heated the planets, leading to their differentiation. Astronomy 2016-10-13T00:00:00Z There isn’t, but there is a technique based on the product rule for differentiation that allows us to exchange one integral for another. Calculus, Vol 2 2016-03-30T00:00:00Z Later on we will encounter more complex combinations of differentiation rules. Calculus, Volume 1 2016-03-30T00:00:00Z Finding derivatives of functions of two variables is the key concept in this chapter, with as many applications in mathematics, science, and engineering as differentiation of single-variable functions. Calculus, Volume 3 2016-03-30T00:00:00Z The process of differentiation is regulated by cellular signaling cascades. Biology for AP Courses 2022-06-09T00:00:00Z Cell differentiation requires genetic specialization, yet most of the cells in a multicellular organism carry the same DNA in their nucleus. Miller & Levine Biology 2018-01-01T00:00:00Z "We found that wolf populations were highly connected throughout the Late Pleistocene, with levels of differentiation an order of magnitude lower than they are today," the scientists write. A new study unlocks secrets of dog domestication 2022-07-15T04:00:00Z For the following exercises, use implicit differentiation to determine y′. Calculus, Volume 1 2016-03-30T00:00:00Z "By implication, the award system apparently exerts a chilling impact on artistic differentiation," the study suggests, "even though the intentions of award sponsors are often the reverse". The unintended side-effects of a Grammy nomination 2022-07-14T04:00:00Z The greater heterogeneity provides more opportunities for coevolution, specialization, and perhaps greater selection pressures leading to population differentiation. Biology for AP Courses 2022-06-09T00:00:00Z Homeobox genes code for transcription factors that activate other genes that are important in cell development and differentiation. Miller & Levine Biology 2018-01-01T00:00:00Z What is differentiation, and what must happen to a planet or asteroid for differentiation to occur?9. Physical Geology 2015-01-01T00:00:00Z Use logarithmic differentiation to find the derivative of y = xx. Calculus, Volume 1 2016-03-30T00:00:00Z The processes affecting magma composition include partial melting, magmatic differentiation, assimilation, and collision. An Introduction to Geology 2017-01-01T00:00:00Z They also control the differentiation of meristem into vascular tissue, and promote leaf development and arrangement. Biology for AP Courses 2022-06-09T00:00:00Z Master control genes are like switches that trigger particular patterns of development and differentiation in cells and tissues. Miller & Levine Biology 2018-01-01T00:00:00Z The separation of silicate minerals and metals into a rocky outer layer and a metallic core, respectively, is called differentiation. Physical Geology 2015-01-01T00:00:00Z We can use the inverse function theorem to develop differentiation formulas for the inverse trigonometric functions. Calculus, Volume 1 2016-03-30T00:00:00Z This temperature differentiation resulted in the inner four planets of the solar system becoming rocky, and the outer four planets becoming gas giants. An Introduction to Geology 2017-01-01T00:00:00Z Researchers hypothesize that mechanical strain induces growth and differentiation to strengthen the tissues. Biology for AP Courses 2022-06-09T00:00:00Z During development, cell differentiation is the process by which cells become specialized for specific functions. Miller & Levine Biology 2018-01-01T00:00:00Z This 30-week period of development is marked by continued cell growth and differentiation, which fully develop the structures and functions of the immature organ systems formed during the embryonic period. Anatomy and Physiology 2013-06-19T00:00:00Z By using implicit differentiation, we can find the equation of a tangent line to the graph of a curve. Calculus, Volume 1 2016-03-30T00:00:00Z This model does not solve the problem of continent formation since magmatic differentiation seems to need a thicker crust. An Introduction to Geology 2017-01-01T00:00:00Z In embryological development, this process of stimulating a group of neighboring cells may help to direct the differentiation of identical cells into the same cell type, thus ensuring the proper developmental outcome. Biology for AP Courses 2022-06-09T00:00:00Z Biologists have determined the pathway of cell differentiation in a microscopic worm, C. elegans. Miller & Levine Biology 2018-01-01T00:00:00Z Throughout development and adulthood, the process of cellular differentiation leads cells to assume their final morphology and physiology. Anatomy and Physiology 2013-06-19T00:00:00Z Use differentiation, applying the chain rule as necessary, to find an equation that relates the rates. Calculus, Volume 1 2016-03-30T00:00:00Z As magma slowly rises and cools into solid rock, it undergoes physical and chemical changes in a process called magmatic differentiation. An Introduction to Geology 2017-01-01T00:00:00Z It is hypothesized that phosphorylation of tyrosine residues is needed to control the more sophisticated functions of development, differentiation, and cellular communication used in multicellular organisms. Biology for AP Courses 2022-06-09T00:00:00Z However, there is a specific point in the development of the organism when cell differentiation is complete. Miller & Levine Biology 2018-01-01T00:00:00Z Figure 3.34 Hematopoiesis The process of hematopoiesis involves the differentiation of multipotent cells into blood and immune cells. Anatomy and Physiology 2013-06-19T00:00:00Z From there, we develop the Fundamental Theorem of Calculus, which relates differentiation and integration. Calculus, Volume 1 2016-03-30T00:00:00Z As magma begins to cool and crystallize, a process known as magmatic differentiation changes the chemistry of the resultant rock towards a more felsic composition. An Introduction to Geology 2017-01-01T00:00:00Z In this image, the chromosomes were exposed to fluorescent stains for differentiation of the different chromosomes. Biology for AP Courses 2022-06-09T00:00:00Z Homeotic genes are master control genes that regulate patterns of development and differentiation in different parts of the body. Miller & Levine Biology 2018-01-01T00:00:00Z The adult stem cells that are present in many organs and differentiated tissues, such as bone marrow and skin, are multipotent, being limited in differentiation to the types of cells found in those tissues. Anatomy and Physiology 2013-06-19T00:00:00Z These new techniques rely on the relationship between differentiation and integration. Calculus, Volume 1 2016-03-30T00:00:00Z Because subduction volcanism occurs in a volcanic arc, the thickened crust promotes partial melting and magma differentiation. An Introduction to Geology 2017-01-01T00:00:00Z The polymorphic aminopeptidase locus, Lap-1, has been shown to be useful for the genetic differentiation of populations of this organism. Biology for AP Courses 2022-06-09T00:00:00Z The process of differentiation gives rise to specialized tissues and organs. Miller & Levine Biology 2018-01-01T00:00:00Z Development includes the process of differentiation, in which unspecialized cells become specialized in structure and function to perform certain tasks in the body. Anatomy and Physiology 2013-06-19T00:00:00Z Part 1 establishes the relationship between differentiation and integration. Calculus, Volume 1 2016-03-30T00:00:00Z Xenoliths are also common in the processes of magma mixing and rejuvenation, two other processes that can contribute to magmatic differentiation. An Introduction to Geology 2017-01-01T00:00:00Z A researcher intends to test the effects of several growth factors on the differentiation of plant tissue. Biology for AP Courses 2022-06-09T00:00:00Z Plant growth happens in meristems, or regions of unspecialized cells in which mitosis produces new cells that are ready for differentiation. Miller & Levine Biology 2018-01-01T00:00:00Z Development also includes the processes of growth and repair, both of which involve cell differentiation. Anatomy and Physiology 2013-06-19T00:00:00Z In the following exercises, verify each identity using differentiation. Calculus, Volume 1 2016-03-30T00:00:00Z “We have tried to be everything to everyone and as a consequence we end up losing relevance and differentiation,” Boone said, referring to challenges of serving all customer groups from one brand. S.Africa retailer Pick n Pay to cut $187 million in costs in 3 years 2022-05-17T04:00:00Z As I walk, I admire the shifting light illuminating the gradients of the canyon’s opposite walls — differentiations that make manifest time itself, according to the geology museum I discover farther along at Yavapai Point. A Writer Returns to the Grand Canyon, This Time With His Mother’s Ashes 2022-05-12T04:00:00Z “The result is a significant disparity of sentences, an appearance of arbitrariness, and potential disrespect of the community because of the appearance of racial differentiation,” Hellerstein wrote. Judge eyes shorter sentence for ex-NYC jails union boss 2022-04-16T04:00:00Z These processes include: organization, in terms of the maintenance of essential body boundaries; metabolism, including energy transfer via anabolic and catabolic reactions; responsiveness; movement; and growth, differentiation, reproduction, and renewal. Anatomy and Physiology 2013-06-19T00:00:00Z For purposes of this section, assume we have not yet defined the natural logarithm, the number e, or any of the integration and differentiation formulas associated with these functions. Calculus, Volume 1 2016-03-30T00:00:00Z I get it — differentiation is hard and expensive. Luminary gets into the exclusive album game 2022-04-12T04:00:00Z This created the differentiation between able-bodied poor people versus those unable to work, and that division has carried on even to our health care and social welfare systems today, Ensign explains. Local author’s ‘Skid Road’ is a look at Seattle’s homeless past 2022-04-08T04:00:00Z One response to this problem is the differential pricing that some theater chains have experimented with, which could be part of a broader differentiation in the experience that different kinds of movies promise. Opinion | We Aren’t Just Watching the Decline of the Oscars. We’re Watching the End of the Movies. 2022-03-25T04:00:00Z Cell differentiation is the process of cells becoming specialized as they body develops. Anatomy and Physiology 2013-06-19T00:00:00Z We also want to verify the differentiation formula for the function y = ex. Calculus, Volume 1 2016-03-30T00:00:00Z "Elsewhere, there's evidence of this simplicity bias in models of neuron development, in studies of plant morphology, in teeth shapes and leaf shapes, and cell differentiation," Camargo elaborated. The weird reason symmetry abounds in nature may have to do with our genes striving for efficiency 2022-03-20T04:00:00Z “This is going to be the new brand differentiation going forward — the battery in electric vehicles,” said Hau Thai-Tang, chief product platform and operations officer at Ford. Carmakers Race to Control Next-Generation Battery Technology 2022-03-07T05:00:00Z “We’re leveraging that same type of experience and engaging with customers to create a product that has a differentiation.” Flying cabs steal thunder at air show as clean future beckons 2022-02-21T05:00:00Z Several sources of stem cells are used experimentally and are classified according to their origin and potential for differentiation. Anatomy and Physiology 2013-06-19T00:00:00Z To do this, we need to use implicit differentiation. Calculus, Volume 1 2016-03-30T00:00:00Z The world is changing: it is transforming into an electric automotive world where you will have less differentiation when it comes to engines. How Volkswagen can reinvent itself as an EV company, with CEO Herbert Diess 2022-01-18T05:00:00Z The Snapdragon phone highlights the chip and its capabilities because you would sell that chip to some phone maker who would add their differentiation. What comes after the smartphone, with Qualcomm CEO Cristiano Amon 2022-01-11T05:00:00Z Companies have used various names to make the process sound less harsh; Welch preferred “differentiation.” Legislature considers constraints on Amazon’s ‘rank-and-yank’ worker ratings 2022-01-10T05:00:00Z Although embryonic stem cells have a nearly unlimited range of differentiation potential, they are seen as foreign by the patient’s immune system and may trigger rejection. Anatomy and Physiology 2013-06-19T00:00:00Z Let’s now apply this definition to calculate a differentiation formula for ax. Calculus, Volume 1 2016-03-30T00:00:00Z This is why we think hardware differentiation will probably be decreased in the future. How Volkswagen can reinvent itself as an EV company, with CEO Herbert Diess 2022-01-18T05:00:00Z “The risk differentiation seems pretty big right now.” With omicron, it may be harder to tell if you have COVID, a cold or the flu 2021-12-23T05:00:00Z "Girls and boys must keep their distinctive identities. Allowing girls to dress up like boys is like initiating them into free sex. It will lead to sexual liberation by ending gender differentiation." Kerala school uniform: Why some Muslim groups are protesting 2021-12-21T05:00:00Z In brief, lymphoid stem cells quickly migrate from the bone marrow to lymphatic tissues, including the lymph nodes, spleen, and thymus, where their production and differentiation continues. Anatomy and Physiology 2013-06-19T00:00:00Z Next, we use this formula to find a differentiation formula for a logarithm with base a. Calculus, Volume 1 2016-03-30T00:00:00Z The differentiation, the competitiveness, and the customer experience will all depend 90 percent on software. How Volkswagen can reinvent itself as an EV company, with CEO Herbert Diess 2022-01-18T05:00:00Z The overall aims of the new engine formula, it said, would be to ensure a "powerful and high-revving power unit, car performance, sound, drivers' ability to race, avoiding excessive differentiation". Abu Dhabi GP 'tarnishing image' of F1 2021-12-15T05:00:00Z The meeting also will see the EU put the emphasis on “differentiation” – the acceptance that some of the six may be in a position to deepen their relations with the bloc more quickly. EU, ex-Soviet state leaders meet as Russia tensions simmer 2021-12-15T05:00:00Z Figure 18.4 Hematopoietic System of Bone Marrow Hemopoiesis is the proliferation and differentiation of the formed elements of blood. Anatomy and Physiology 2013-06-19T00:00:00Z In this section, we look at differentiation and integration formulas for the hyperbolic functions and their inverses. Calculus, Volume 1 2016-03-30T00:00:00Z Software will be decisive for the differentiation and for gaining the economies of scale, so we will become a software company as well — talking to the customer and delivering day in and day out. How Volkswagen can reinvent itself as an EV company, with CEO Herbert Diess 2022-01-18T05:00:00Z The district defines differentiation as “designing instruction to meet individual needs.” Perspective | Charlottesville labeled 86 percent of students as gifted. Will learning improve? 2021-11-12T05:00:00Z "Jiebei is gradually working on brand differentiation," an Ant Group spokesperson said, adding that consumer credit services provided independently by banks or other financial institutions will be presented on a "credit loan" page. Ant Group starts to differentiate consumer loan business Jiebei from bank loans 2021-11-08T05:00:00Z Researchers now suspect that interleukins may play other roles in body functioning, including differentiation and maturation of cells, producing immunity and inflammation. Anatomy and Physiology 2013-06-19T00:00:00Z It is easy to develop differentiation formulas for the hyperbolic functions. Calculus, Volume 1 2016-03-30T00:00:00Z Over the past year alone, New York City, the nation’s biggest school system, began phasing out its “gifted and talented” programs, arguing that such differentiation exacerbates disparities. Perspective | School culture wars stirred up voters for a reason: Classrooms really did change 2021-11-05T04:00:00Z "It says a lot about the differentiation between real people," Maher said. Bill Maher defends Dave Chappelle, knocks critics: 'Everyone needs to Netflix and chill the f--- out' 2021-10-23T04:00:00Z Ant did not elaborate on how much of its business would be affected by the brand differentiation. Ant Group starts to differentiate consumer loan business Jiebei from bank loans 2021-11-08T05:00:00Z This early release of testosterone results in the anatomical differentiation of the male sexual organs. Anatomy and Physiology 2013-06-19T00:00:00Z We summarize the differentiation formulas for the hyperbolic functions in the following table. Calculus, Volume 1 2016-03-30T00:00:00Z And we’ll get even more differentiation between brands, because we’ll put the money where the customer really wants and not in the core or base technology, the connectivity, autonomous drive, or the electrification. How Jeep is going electric, with CEO Christian Meunier 2021-10-19T04:00:00Z There is this differentiation about being auditory or visual learner. Even "low-level" noise is unhealthy: A neuroscientist explains how sound and health are connected 2021-10-17T04:00:00Z In general, we need to enable teachers and classes for differentiation to meet our students’ needs. Alexandria school board race: Meet the candidates running in each district 2021-10-16T04:00:00Z In this section, we’ll cover the pre-embryonic and embryonic stages of development, which are characterized by cell division, migration, and differentiation. Anatomy and Physiology 2013-06-19T00:00:00Z To find the derivatives of the inverse functions, we use implicit differentiation. Calculus, Volume 1 2016-03-30T00:00:00Z Instead of spending money on common technologies and common architecture, that really are common for 90 percent of the use cases, we spend the money on differentiation. How Jeep is going electric, with CEO Christian Meunier 2021-10-19T04:00:00Z But that requires many thousands of city educators to pull off some of the hardest work in public education: teaching children with a large range of abilities in one classroom, a practice known as differentiation. De Blasio to Phase Out N.Y.C. Gifted and Talented Program 2021-10-08T04:00:00Z Health and safety, followed by rigorous instructional practices that meet every child’s needs through differentiation. Alexandria school board race: Meet the candidates running in each district 2021-10-16T04:00:00Z Later, the bone marrow takes over most hematopoietic functions, although the final stages of the differentiation of some cells may take place in other organs. Anatomy and Physiology 2013-06-19T00:00:00Z We can derive differentiation formulas for the other inverse hyperbolic functions in a similar fashion. Calculus, Volume 1 2016-03-30T00:00:00Z In several cases representing individuals, Yagman shows no lessening of his sharp differentiation between the just and unjust. A fraud conviction ended his battles for civil rights. 14 years later, Stephen Yagman is back 2021-10-08T04:00:00Z While being driven home from the hospital, she saw the marshes and exclaimed: “God, the color differentiation is gorgeous.” A ‘Pacemaker for the Brain’: No Treatment Helped Her Depression — Until This 2021-10-04T04:00:00Z Acceleron, based in Massachusetts, is working with the transforming growth factor-beta superfamily of proteins that is known to play a central role in the regulation of cell growth, differentiation and repair. Merck buying Acceleron Pharma in $11.5B deal 2021-09-30T04:00:00Z Plasma cells often leave the secondary lymphoid organs, where the response is generated, and migrate back to the bone marrow, where the whole differentiation process started. Anatomy and Physiology 2013-06-19T00:00:00Z These differentiation formulas are summarized in the following table. Calculus, Volume 1 2016-03-30T00:00:00Z The snack bars were launched in 2016 in a range of colours so that "they have good differentiation on a shelf together", said Adam Draper, managing director of Nurture Brands. Mondelez threatens trademark battle over bar's lilac packaging 2021-09-24T04:00:00Z The pharmacy also fills orders using specialized equipment and can provide enhanced packaging with tactile differentiations for morning and night doses. Specialty Pharmacies Cater to the Blind and Those with Impaired Vision 2021-09-21T04:00:00Z In particular, baroque and classical music is of course a point of differentiation. Castlevania composer on returning to her ‘masterpiece’ with new Apple Arcade game 2021-09-18T04:00:00Z For more information and a figure of differentiation of the gonads, seek additional content on fetal development. Anatomy and Physiology 2013-06-19T00:00:00Z These differentiation formulas give rise, in turn, to integration formulas. Calculus, Volume 1 2016-03-30T00:00:00Z The rice is one major point of differentiation. This veggie jollof recipe with Ghanaian roots is a great way to appreciate the West African staple 2021-09-02T04:00:00Z “So that was the reason for that differentiation.” Titans’ Vrabel good with player vaccinations entering camp 2021-07-27T04:00:00Z We want to create true differentiation and preference for our products. Bed Bath & Beyond CEO Mark Tritton on the changing home 2021-07-20T04:00:00Z Its endocrine function is the production of a group of hormones called thymosins that contribute to the development and differentiation of T lymphocytes, which are immune cells. Anatomy and Physiology 2013-06-19T00:00:00Z Implicit differentiation yields differentiation formulas for the inverse hyperbolic functions, which in turn give rise to integration formulas. Calculus, Volume 1 2016-03-30T00:00:00Z “The bottle is our most significant point of differentiation,” the company’s website says. They want to age wine in the ocean off Santa Barbara. The Coastal Commission is wary 2021-07-15T04:00:00Z Based on a single color, a monochromatic color scheme uses various shades and tones to add a sense of differentiation within a space. Create a design that dazzles with a monochromatic color scheme 2021-06-22T04:00:00Z By using this outdated practice, physicians may be reinforcing the incorrect idea that race differentiation holds scientific value instead of being a clumsy artifact of the profession. A Tool Doctors Use Every Day Can Perpetuate Medical Racism 2021-06-07T04:00:00Z It facilitates the proliferation and differentiation of the erythrocyte lineage. Anatomy and Physiology 2013-06-19T00:00:00Z And back then there was still this differentiation between a New York actor and an LA actor. ‘Pretty in Pink’ star Andrew McCarthy on Brat Pack fame, facing alcohol abuse: ‘It was so all-consuming’ 2021-05-29T04:00:00Z I think the differentiation is key to preserving freedom of expression. Facebook’s Oversight Board has upheld Trump’s ban — what’s next? 2021-05-11T04:00:00Z It's unclear how exactly the differentiation would occur. Virginia moving to eliminate all accelerated math courses before 11th grade as part of equity-focused plan 2021-04-22T04:00:00Z While three sticks will technically fill you up, they come with two significant issues: one, little differentiation between bites, and two, a whole lot of guilt over so much fried food. Review | These Korean snacks look like corn dogs. But they’re so much more. 2021-02-26T05:00:00Z Th2 cells, on the other hand, are cytokine-secreting cells that act on B cells to drive their differentiation into plasma cells that make antibody. Anatomy and Physiology 2013-06-19T00:00:00Z Thomas-Greenfield told reporters Wednesday that representing the United States as a diplomat around the world, “I found that diplomacy is about showing compassion, it’s about managing points of differentiation and it’s about bringing people together.” New US envoy starts challenge to restore US on world stage 2021-02-25T05:00:00Z But he was swamped with questions about how an officer might make such differentiations. Supreme Court considers giving police greater powers when pursuing suspects 2021-02-24T05:00:00Z “It means finding common ground and managing points of differentiation. It means doing genuine, old-fashioned, people-to-people diplomacy.” Biden’s pick for UN post says US will counter China’s agenda 2021-01-27T05:00:00Z "There's increasing logic for Samsung to converge the Galaxy S and Note platforms, because there's so little differentiation between the two kinds of devices now," said Ben Wood, from the CCS Insight consultancy. Samsung Galaxy S21 Ultra: Does stylus spell end of the Note? 2021-01-14T05:00:00Z B cell differentiation and the development of tolerance are not quite as well understood as it is in T cells. Anatomy and Physiology 2013-06-19T00:00:00Z Ennos argues that our forward-facing eyes with binocular vision, upright posture and differentiation between hind limbs for locomotion and forelimbs for gripping all evolved for living in canopies. Review | How wood shaped human history, from spears to boats to books 2020-12-30T05:00:00Z “It is something that we would like to honor the cultural and the social aspects of. So I think we need to find a balance and the differentiation between the two.” Resort project near Navajo Nation stirs culture controversy 2020-12-19T05:00:00Z “We’re seeing a huge differentiation in quality among all these corporate commitments.” North American farmers profit as consumers pressure food business to go green 2020-12-03T05:00:00Z “But on the ground, we’re not seeing a lot of differentiation between Christians and Muslims. They do not appear to be targeting churches in particular, for instance.” With Village Beheadings, Islamic State Intensifies Attacks in Mozambique 2020-11-11T05:00:00Z These memory cells lead to the differentiation of more plasma cells and memory B cells during secondary responses. Anatomy and Physiology 2013-06-19T00:00:00Z The interior is also a chance for differentiation. Edmunds: 2021 Toyota Sienna versus Honda Odyssey 2020-11-11T05:00:00Z GM, Nissan and some other carmakers believe e-axles offer such a large margin for cost efficiencies and product differentiation that they want to design and manufacture their own systems. From iPhones to e-axles: how one tech firm is pushing into electric vehicles 2020-10-14T04:00:00Z Leucism occurs when some or all pigment cells fail to develop during differentiation, so part or all of the animal’s body surface lacks cells capable of making pigment. Rare all-white shark found: 'The fish of a lifetime' 2020-10-05T04:00:00Z “But I don’t put a lot of emphasis on the differentiation between light sleep and deep sleep.” The Withings ScanWatch knows when you’re sleeping and when you’re awake, but not why 2020-09-28T04:00:00Z In contrast with embryonic stem cells, hematopoietic stem cells are present throughout adulthood and allow for the continuous differentiation of blood cells to replace those lost to age or function. Anatomy and Physiology 2013-06-19T00:00:00Z “Originally when I started learning differentiation on my own it was kind of twitchy,” he said. In pandemic, Nigerian teacher can ‘teach the whole world’ 2020-09-07T04:00:00Z "I think you will find if you dig below the surface of some of the surface differentiations you will find overwhelmingly the UK takes the same approach," he said. Portugal quarantine rules come into force 2020-09-04T04:00:00Z The final stage of differentiation generates a layer of dead cells on the skin’s surface, which are continually shed. How cancer invasion takes shape 2020-09-01T04:00:00Z “You are making a claim that something is art, and this differentiation is, of course, like creating a sort of hierarchy. You cannot circumvent that. It’s not a democratic process,” she says. The Photographer Capturing Unvarnished Truths 2020-08-27T04:00:00Z Figure 21.5 Hematopoietic System of the Bone Marrow All the cells of the immune response as well as of the blood arise by differentiation from hematopoietic stem cells. Anatomy and Physiology 2013-06-19T00:00:00Z “But when I joined the online maths platform, I started slow at first, but with the way my maths teacher was teaching, holding the sessions, I started learning differentiation rapidly.” In pandemic, Nigerian teacher can ‘teach the whole world’ 2020-09-07T04:00:00Z Have a look at seed catalogues to get an idea for the visual differentiation. Eggplant can be a love-or-hate proposition. Here’s how to treat it right. 2020-08-03T04:00:00Z These cells, through cytoskeletal reorganization and changes in gene expression, coordinate stem-cell renewal and differentiation with adaptation to the mechanical force being experienced. Stretch exercises for stem cells expand the skin 2020-07-28T04:00:00Z The zonation pattern is determined according to the dosage of this regulator; high levels activate stem cells, low levels promote cell division, and very low levels are needed for differentiation to occur7. Growth-mediated sensing of long-term cold in plants 2020-07-14T04:00:00Z This ecological differentiation most likely worked hand in hand with increased physical separation to promote reproductive isolation between populations. How Oak Trees Evolved to Rule the Forests of the Northern Hemisphere 2020-07-14T04:00:00Z In addition to problems with neuronal integration, current approaches to stem-cell differentiation result in a mixed cell population from which only a relatively low percentage of grafted cells become dopaminergic neurons. Parkinson’s disease grafts benefit from well-timed growth factor 2020-05-25T04:00:00Z “It’s stuck in the middle with no differentiation.” J.C. Penney, 118-Year-Old Department Store, Files for Bankruptcy 2020-05-15T04:00:00Z Third, current models of stem-cell renewal postulate that a single stem cell is equally capable of undergoing renewal or differentiation. Stretch exercises for stem cells expand the skin 2020-07-28T04:00:00Z The different cell types in a tumor arise by differentiation from a kind of cancer “stem cell”—just as normal cells differentiate in ordinary tissues in a developing embryo. Close-Up Views of Tumors Reveal a New Cancer Biology 2020-04-21T04:00:00Z Ecological differentiation within the red and white oaks is influenced in part by the fact that no single species is able to master every habitat. How Oak Trees Evolved to Rule the Forests of the Northern Hemisphere 2020-07-14T04:00:00Z The league and players believe there will be further refinement and additional differentiation among the best-performing models beginning next year. New data lead to new testing, results for NFL helmets 2020-04-20T04:00:00Z “Rigorous differentiation delivers real stars — and stars build great businesses,” Mr. Welch wrote. Jack Welch, G.E. Chief Who Became a Business Superstar, Dies at 84 2020-03-02T05:00:00Z Communication within and between units would balance the loss of cells through differentiation with renewal. Stretch exercises for stem cells expand the skin 2020-07-28T04:00:00Z Cancer cell differentiation also seems to be more fluid than that of healthy cells. Close-Up Views of Tumors Reveal a New Cancer Biology 2020-04-21T04:00:00Z We are close to understanding what genes shape differentiation. How Oak Trees Evolved to Rule the Forests of the Northern Hemisphere 2020-07-14T04:00:00Z Writing in Cell, Waldman et al.3 report the identification of a gene that encodes a master regulator of this differentiation event. One gene to rule them all in a chronic brain infection 2020-03-01T05:00:00Z To be straight, white and male is taxonomy enough in today’s politics, with no further differentiation required or desired. Opinion | Joe Biden, the last of his political species 2020-02-11T05:00:00Z Tracking of these cell lineages over time confirmed that stretching tips the renewal–differentiation balance in favour of making more stem cells. Stretch exercises for stem cells expand the skin 2020-07-28T04:00:00Z However, when the researchers tracked MeSCs labelled with a fluorescent protein, they discovered that MeSC proliferation and differentiation increase markedly under extreme stress or exposure to a high level of noradrenaline. How the stress of fight or flight turns hair white 2020-01-21T05:00:00Z Those 200 years or older also saw decreases in gene expression associated with cell division, differentiation, and expansion. How the Ginkgo biloba achieves near-immortality 2020-01-13T05:00:00Z Many questions remain unanswered regarding BFD1’s regulation of differentiation, and how it might act upstream of a group of previously identified transcription factors called ApiAP2s, which are important, but not sufficient, for differentiation7. One gene to rule them all in a chronic brain infection 2020-03-01T05:00:00Z On PragerU’s website, there is little differentiation between its video presenters. Right-Wing Views for Generation Z, Five Minutes at a Time 2020-01-04T05:00:00Z People with better emotion differentiation recover more quickly from stress and are at less risk of developing depression. Wellbeing: six ways to put a smile back on your face in 2020 2020-01-04T05:00:00Z When proliferation was dampened, the effects of stress on MeSC proliferation, differentiation and migration were blocked. How the stress of fight or flight turns hair white 2020-01-21T05:00:00Z These are dramatic costs to attempt to achieve performance differentiation. Golf equipment truths: Are the prices for new clubs out of control? - Golf Digest 2020-01-02T05:00:00Z Considering that BFD1 is probably regulated by translational control, approaches that determine the RNA content of single cells might not be enough to identify the full cohort of factors driving differentiation. One gene to rule them all in a chronic brain infection 2020-03-01T05:00:00Z Thornberry has better differentiation from the old days, but was more compromised by her time in the shadow cabinet, especially in the runup to the election, when the party Rees-Mogged her. The task Labour members face is first and foremost: listen | Zoe Williams 2019-12-16T05:00:00Z Fortunately, emotion differentiation seems to improve with practice. Wellbeing: six ways to put a smile back on your face in 2020 2020-01-04T05:00:00Z “Our state charge makes no differentiation between domestic terrorism and foreign terrorism, and there is a material support charge.” With Rise of Far-Right Extremists, N.Y.P.D. Creates Special Unit 2019-12-11T05:00:00Z Yet the differentiation of T cells into cytotoxic CD8 T cells impairs successful retention of the potential to form long-lived memory cells. Antitumour T cells stand the test of time 2019-12-10T05:00:00Z The segue to differentiation began immediately after the abbreviated period of cellular reproduction. Research Using Brains-in-a-Dish Forces a Radical Rethinking of Huntington’s Disease 2019-12-10T05:00:00Z That would become the point of differentiation for golfers. USGA/R&A to explore letting amateurs sign endorsement deals as part of overall review of the Rules of Amateur Status - Golf Digest 2019-12-09T05:00:00Z The aim was to improve standards by making courses harder, and increase differentiation at the top of the grade range. New GCSEs 'widen gap between rich and poor' 2019-12-04T05:00:00Z So it is noteworthy that, in a historically large field, there is little differentiation among the candidates on abortion rights — even among the more moderate candidates who, on other issues, have emphasized courting swing voters. On Abortion Rights, 2020 Democrats Move Past ‘Safe, Legal and Rare’ 2019-11-25T05:00:00Z This exchange leads to conformational changes in KRAS, to binding of the protein Raf and so to activation of downstream signalling pathways that control cell growth and differentiation. Small molecule combats cancer-causing KRAS protein at last 2019-11-07T05:00:00Z More CAG repeats predicted more lingering in the first phase, less time for proliferating, and more premature differentiation. Research Using Brains-in-a-Dish Forces a Radical Rethinking of Huntington’s Disease 2019-12-10T05:00:00Z The extracellular matrix also provides essential cues for growth, cell orientation and differentiation. Growing Meat in a Lab That Doesn’t Look Like Mush 2019-10-27T04:00:00Z “I’m really looking for any differentiation on policy and personal interaction between him and others, like Elizabeth Warren and Beto O’Rourke.” Democratic voters concentrate on candidates, not impeachment 2019-10-18T04:00:00Z A developing tissue, she says, might decide: “Why not just remove losers through differentiation?” These secret battles between your body’s cells might just save your life 2019-10-14T04:00:00Z Thus, Briggs and King’s results demonstrated that the nuclei in blastomeres are not irreversibly changed with differentiation. Cell identity reprogrammed 2019-10-13T04:00:00Z Christina Reynolds, a Clinton 2016 spokeswoman, said that the former Democratic nominee “is commenting in a forward-looking way” while Trump “is commenting in a backward-looking way” — a differentiation echoed by several Clinton allies. ‘Crooked Hillary’ vs. the ‘corrupt human tornado’: How Clinton and Trump can’t seem to quit each other 2019-10-03T04:00:00Z In neurons, synaptic activity enables the depolarization and calcium-ion influx that is necessary for cellular differentiation, proliferation and survival. Dangerous liaisons as tumour cells form synapses with neurons 2019-09-17T04:00:00Z The timing of metastasis initiation varies depending on the size, stage and differentiation status of the tumour at the primary site1. Survival skills ensure that cancer spreads 2019-09-03T04:00:00Z It suggested loyalty; wasn’t I supposed to be looking for differentiation? A Year Without a Name 2019-08-12T04:00:00Z Despite this discordance, both groups agreed that the advance of a nucleus through differentiation was accompanied by a reduction in its ability to support normal development. Cell identity reprogrammed 2019-10-13T04:00:00Z The power game that college players display also is a point of differentiation from mid-ams. How an NHL referee's inspiring golf win has changed the outlook of the upcoming U.S. Amateur - Golf Digest 2019-08-10T04:00:00Z Mr. Schoenfeld cited a “key differentiation” that gave investigators an advantage: the Republican club provided them with a list of people who had obtained tickets for Mr. McInnes’s talk. How Police Used Antifa Information to Investigate Far-Right Proud Boys 2019-08-08T04:00:00Z “For the fish raised in Patagonia, their differentiation will be the purity of their waters.” Data rigging is latest Chile salmon farm scandal 2019-08-04T04:00:00Z The percentage of differentiation reflects the tumor’s aggressiveness: the higher the percentage, the more aggressive the tumor. ‘Maybe you’re just someone with blood in their urine’ 2019-07-26T04:00:00Z However, they also indicated that, as development progresses, the potential of transplanted nuclei to support normal development decreases — suggesting that cell differentiation might be irreversible and might involve irreversible genetic changes. Cell identity reprogrammed 2019-10-13T04:00:00Z “To be honest, the value differentiation using blockchain from using traditional technology has not been obvious,” he said. Wall Street finds blockchain hard to tame after early euphoria 2019-07-16T04:00:00Z However, CALR-mutant cells were more likely to follow certain differentiation pathways and therefore to become certain types of blood cell. How mutations express themselves in blood-cell production 2019-07-02T04:00:00Z “As these stocks sold off, there hasn’t be any differentiation, in terms of their product mix,” he said. Resurgent health insurer stocks face test at Democratic debates 2019-06-26T04:00:00Z Also expect quizzing on healthcare, a real point of differentiation where some contenders support Medicare for All, some are only up for improving Obamacare, and others are somewhere in the middle. Democratic debates 2019: everything you need to know 2019-06-26T04:00:00Z Together, this rich history of nuclear transfer revealed that cell differentiation can be reversed, resetting cell identity to the earliest embryonic stages. Cell identity reprogrammed 2019-10-13T04:00:00Z Consumers in both cities seek differentiation from the “condo-commodity” and authentic neighborhoods that are reborn. Condominiums located in Seattle’s ‘new Brooklyn’ | Provided by Gridiron Condominiums 2019-06-20T04:00:00Z The book’s main argument goes something like this: There is to be no elite in America, no linguistic differentiation between classes and regions. Mueller exits, says Congress must decide Trump’s fate 2019-05-29T04:00:00Z “Our instinct as universities is to seek differentiation — to compete with one another,” George Mason President Ángel Cabrera said. Businesses and universities team up on a new digital technology credential 2019-05-19T04:00:00Z An ideal protocol would promote the differentiation of stem cells into fully mature α-cells and β-cells, which would then be isolated, purified and reassembled into islet-like structures for transplantation into patients. A map of β-cell differentiation pathways supports cell therapies for diabetes 2019-05-07T04:00:00Z Gurdon and colleagues’ 1950s conclusions that the developmental clock can be reset challenged the long-standing theory at that time that cell differentiation is an irreversible process. Cell identity reprogrammed 2019-10-13T04:00:00Z And there’s plenty of room to compete in differentiation.” Inside Microsoft’s surprise decision to work with Google on its Edge browser 2019-05-06T04:00:00Z The authors also characterized cellular transcription dynamics in a mouse model of traumatic brain injury, revealing that an initial wave of cell proliferation after injury was followed by cellular differentiation. Pinpointing a spatial address for RNA profiles in tissues 2019-05-02T04:00:00Z The absence of Rb resulted in loss of cellular differentiation and an increase in the spread of cancer cells to other sites in the body through a process called metastasis. Manipulating the tumour-suppressor protein Rb in lung cancer reveals possible drug targets 2019-04-30T04:00:00Z To achieve such an ambitious goal, the differentiation programs of all islet cells, and the way in which islets are built, need to be fully understood. A map of β-cell differentiation pathways supports cell therapies for diabetes 2019-05-07T04:00:00Z Such women, he wrote, were “servants to whom, in the differentiation of economic functions, has been delegated the office of putting in evidence their master’s ability to pay.” The man who saw Trump coming a century ago 2019-04-19T04:00:00Z “The big differentiation at Mountain Vista at Cedar Falls is you get the same quality Toll Brothers house you’d get in Seattle, but without the hustle and bustle and city noise,” says Finney. Community features luxury homes, mountain views | Provided by Toll Brothers 2019-04-11T04:00:00Z As the first Latino to run a major bid for the Democratic nomination since Bill Richardson in 2008, he has been leaning on his Hispanic credentials as a point of differentiation. Julián Castro: mayor, housing secretary and America's first Latino president? 2019-04-01T04:00:00Z Bicknell & Co., and “The American Builder’s Companion” by Asher Benjamin — that show historical precedence, proportions, molding shape used during specific eras, and style differentiation between, say, Victorian gingerbread and gothic revival. 7 mistakes to avoid when renovating older houses | Produced by Advertising Publications 2019-03-28T04:00:00Z Therefore, the authors’ road map of in vitro islet-cell differentiation will inform the development of future differentiation protocols. A map of β-cell differentiation pathways supports cell therapies for diabetes 2019-05-07T04:00:00Z "Like rival smartphone-makers, the company faces a tough challenge to convince people that there is enough differentiation in the new devices to justify upgrading, particularly given their premium price tags," Mr Wood said. Huawei shows off flagship camera phone 2019-03-26T04:00:00Z In the run-up to its initial public offering next month, Uber is expected to tout its global reach and strong overseas markets to investors as a differentiation from U.S. rival Lyft. Uber drives Middle East mapping push ahead of IPO: source 2019-03-25T04:00:00Z This process, called differentiation, allowed heavier constituents like iron to sink to the interior. Metal world 'may have iron volcanoes' 2019-03-18T04:00:00Z This is because of the process of differentiation, in which relatively heavy materials sink and lighter materials rise when a planetary body is partially or almost fully molten. Mining the moon 2019-03-17T04:00:00Z Endocrine induction — the formation of hormone-producing cell types in the pancreas — is a key step in the differentiation of islet cells from stem cells. A map of β-cell differentiation pathways supports cell therapies for diabetes 2019-05-07T04:00:00Z The key to selling any product is differentiation, making your car seem cooler and more capable than all the others. Automakers Retool Marketing Machines as They Go Electric 2019-03-10T05:00:00Z I’m a big fan of this collaboration, as it still leaves room for differentiation between the various car manufacturers — on the basis of providing a more intuitive UX or more accurate battery life estimates. The Polestar 2’s secret weapon against the Tesla Model 3 is native Android Auto 2019-03-06T05:00:00Z “When we first got to the State, everything was orderly. There was no differentiation between Iraqi or Syrian or foreigner,” she said. To the bitter end, IS militants remain organized and brutal 2019-03-05T05:00:00Z Indeed, it’s because minor bodies such as asteroids generally don’t undergo differentiation that they’re such promising targets for mineral exploration and extraction. Mining the moon 2019-03-17T04:00:00Z It also revealed the order in which these cell types emerge, and the dynamic molecular changes that occur along each differentiation trajectory. A map of β-cell differentiation pathways supports cell therapies for diabetes 2019-05-07T04:00:00Z The mechanisms that regulate the sequence of differentiation of both stem-cell types are, however, still to be deciphered. A newly discovered stem cell that keeps bones growing 2019-02-26T05:00:00Z And in what ways are such differentiations nestled within streamed financial logics? What happens when you create a fake music record label and upload bad music to Spotify 2019-02-17T05:00:00Z Rival scouts and Dodgers officials noted the lack of differentiation between his fastball and his slider. Clayton Kershaw heads into Dodgers' season 'trying to regain some stuff I lost' 2019-02-12T05:00:00Z “We think big retailers are really leaning into this and it’s going to provide great differentiation for them.” FedEx to help retailers compete with Amazon with next-day delivery option 2019-01-29T05:00:00Z “Anything they’re working to market, they’re looking for differentiation of their product, and trying to describe it in a way that creates excitement for consumers,” he said. The names car companies use to describe their high-tech features sound like gibberish 2019-01-29T05:00:00Z Such accumulation of these cells might result from proliferation and differentiation of existing T cells in the colon, recruitment of the cells from elsewhere in the body, or a combination of both. A gut punch fights cancer and infection 2019-01-22T05:00:00Z The Austronesians and the Papuans had been separated by at least 40,000 years of genetic differentiation, which meant that it would be very easy to discriminate by genetic signature. Is Ancient DNA Research Revealing New Truths — or Falling Into Old Traps? 2019-01-17T05:00:00Z "You are not criminalising the speech, you are criminalising the behaviour. And that is a differentiation that is not seen in the US." How far do free speech protections go in the US? 2019-01-18T05:00:00Z “In a market with 450 million square feet of office space to choose from,” he added, “it’s a way of creating differentiation.” The Next Frontier in Office Space? The Outdoors 2019-01-15T05:00:00Z How much differentiation is enough differentiation for something to become an original work of dance? Fortnite keeps stealing dances — and no one knows if it’s illegal 2018-12-20T05:00:00Z The authors confirmed this supposition in vitro, showing that overexpression of GABPα in muscle progenitors leads to their differentiation into fat. Fat cells with a sweet tooth 2018-12-18T05:00:00Z It’s often said of Stoppard, as a point of differentiation from other playwrights, that he is uniquely interested in presenting complex ideas onstage. The Incarnation of Ideas in Tom Stoppard’s “The Hard Problem” 2018-12-03T05:00:00Z Cells from the outer layer of the blastocyst, called trophoblast cells, undergo differentiation. Cell atlas reveals the landscape of early pregnancy 2018-11-13T05:00:00Z Both studies look for “differentiation,” when a type of traffic on a network is treated differently than other types of traffic. Sprint Is throttling Microsoft’s Skype service, study finds 2018-11-08T05:00:00Z The differentiation cascade terminates with the formation of fully differentiated, mature muscle cells called myofibres, which contain multiple nuclei. b, By contrast, the liver contains no known professional stem cells. Definitions for adult stem cells debated 2018-10-28T04:00:00Z For such approaches to be successful, researchers would first need to determine how g-beige fat is induced, including which receptors and subsequent signalling cascades trigger GABPα-mediated differentiation. Fat cells with a sweet tooth 2018-12-18T05:00:00Z But the court did allow questions for another official, from the Justice Department, spawning a dissent by Gorsuch and Justice Clarence Thomas that said this differentiation made no sense. Trump’s quick return on his Supreme Court investment 2018-10-29T04:00:00Z The authors found that VCT cells express receptors that promote differentiation and are stimulated by growth factors produced by various placental cells. Cell atlas reveals the landscape of early pregnancy 2018-11-13T05:00:00Z The final differentiation for the M10-D is the genuine leather wrap that covers most of the camera; prior models used a leather-like polyurethane wrap. Leica’s new M10-D is a digital camera with an analog soul 2018-10-24T04:00:00Z In order for a mechanism of oppression to exist between two classes in society, differentiation between them is crucial. Authoritarians like Trump target trans people for a reason | Mischa Haider 2018-10-22T04:00:00Z And that’s the slight differentiation between all-out gore and what we were trying to achieve with this. Gareth Evans on Apostle’s restrained approach to extreme gore 2018-10-16T04:00:00Z Eicher Motors said in a statement that “all employees are treated equally without differentiation by level or location.” Labor strife in India's manufacturing hubs may undermine Modi's... 2018-10-15T04:00:00Z The inability of Clayton Kershaw to finish at-bats plagued him during the final month of the season, as hitters became more comfortable with the lack of differentiation between his fastball and his slider. Similarities of pitches could be hampering Clayton Kershaw's performance - Los Angeles Times 2018-10-13T04:00:00Z We must develop standardized analyses of gene expression, including on a cell-by-cell basis, and rigorous assays to establish the precise products of cell differentiation in various tissues. Clear up this stem-cell mess 2018-09-25T04:00:00Z Paltrow also serves another handy retail function, says Northwestern University marketing professor Tim Calkins: “Celebrity brands bring differentiation. When there are many choices, the celebrity brand stands out.” Ready to let Gwyneth Paltrow move into your living room? | Produced by Advertising Publications 2018-09-13T04:00:00Z As India’s official guidelines put it: “A differentiation should be made between ‘human kill’ due to chance encounters and ‘habituated man-eaters.’ Hunters of Man-Eating Tigress Can Shoot to Kill, Indian Court Rules 2018-09-11T04:00:00Z Her concern was that historically, when education access improves, there is a corresponding differentiation in how students are educated. The comeback kids: the struggling public school that turned itself around 2018-09-06T04:00:00Z Next, the authors used a different gene-editing approach to generate human neural progenitor cells lacking SIRT6 in vitro, and showed that the differentiation of these cells into neurons was delayed when compared with wild-type cells. Role for the longevity protein SIRT6 in primate development 2018-08-21T04:00:00Z But reports exist of their differentiation into muscle, endothelium and various cells of the heart, liver and kidney, as well as of the nervous and reproductive systems. Clear up this stem-cell mess 2018-09-25T04:00:00Z There are 14,000 species of ants, all of which are believed to share the same mechanism of differentiation between queens and workers. Worker Ants: You Could Have Been Queens 2018-07-26T04:00:00Z "As smartphones become more high-spec and product differentiation is becoming less clear, the global handset replacement cycles are getting longer," said one representative. Is Samsung's Galaxy S9 flagship a flop? 2018-07-31T04:00:00Z JOBS: Well, our theory on iPhone is that phone differentiation used to be about radios and antennas and things like that. ‘The Mobile Industry’s Never Seen Anything Like This’: An Interview With Steve Jobs at the App Store’s Launch 2018-07-25T04:00:00Z In fact, his recurrent theme was his industry’s penchant for wasting capital on duplicative under-the-hood differentiation that held no value for consumers. A Workaholic Saved Chrysler 2018-07-24T04:00:00Z Kate and Jonathan report 20 percent of people who took the drug in a clinical trial also developed a condition known as differentiation syndrome, which causes organs to swell. Analysis | The Health 202: HHS Secretary Alex Azar stars in liberal group's attack ads on migrant crisis 2018-07-23T04:00:00Z The researchers next built a circuit to generate differential gene expression in a population of cells that was initially identical — a process that mimics cell differentiation. Self-organizing multicellular structures designed using synthetic biology 2018-07-01T04:00:00Z Image quality is subpar: busy scenes tend to lack detail, color differentiation, and overall photos are just grainy. BlackBerry Key2 review: a keyboard with a phone 2018-06-27T04:00:00Z This differentiation reflects how today’s black ghetto differs from the ghetto under the rule of Jim Crow. This is what it feels like to be black in white spaces | Elijah Anderson 2018-06-09T04:00:00Z The self-renewal, proliferation and differentiation of these intestinal stem cells are prompted by molecular signals from nearby cells called niche cells. Debate over the identity of an intestinal niche-cell population settled 2018-06-05T04:00:00Z Bryan: Even that speaks to the larger point of differentiation, though. Where should Star Wars go after Solo’s box-office disappointment? 2018-06-01T04:00:00Z In it, he followed the fortunes of middle-class Jewish Americans caught between the old ways and the new, negotiating the boundaries between assimilation and differentiation in suburbia. Philip Roth: Portnoy's Complaint and American Pastoral author dies aged 85 2018-05-22T04:00:00Z When the researchers looked at population structure within the three mammal species, there was clear genetic and morphological differentiation between populations in different regions of the island. Wallace’s enigma: how the island of Sulawesi continues to captivate biologists 2018-05-17T04:00:00Z Transcriptome dynamics of developing photoreceptors in three-dimensional retina cultures recapitulates temporal sequence of human cone and rod differentiation revealing cell surface markers and gene networks. Restoring vision 2018-05-15T04:00:00Z Refs 68 and 69 were among the first to report differentiation of hES cells toward pancreatic endocrine progenitors and islet cells. Pancreas regeneration 2018-05-15T04:00:00Z The authors also showed that the increase in the reach and activation of super-enhancers led to the activation of genes involved in squamous-subtype-like differentiation. Pancreatic cancer foiled by a switch of tumour subtype 2018-05-13T04:00:00Z Outliers are displayed as open circles. c, Analysis of genetic diversity and differentiation. Genome sequence of the progenitor of wheat A subgenome Triticum urartu 2018-05-08T04:00:00Z A technical advisory committee at the Department of Education endorsed eliminating the four categories because the group felt there weren’t sufficient test questions to provide that differentiation. Editorial Roundup: Recent editorials in Oklahoma newspapers 2018-05-08T04:00:00Z “The variation in earth’s magnetic field around the nesting area seems to really predict genetic differentiation much better than geographic distance.” Sea Turtles Use Magnetic Fields to Find Their Birthplace Beach 2018-04-13T04:00:00Z A dual program for translation regulation in cellular proliferation and differentiation. An evolutionarily conserved ribosome-rescue pathway maintains epidermal homeostasis 2018-04-10T04:00:00Z REI plans to promote products with these attributes, creating an incentive for companies to continue pursuing more ambitious sustainability goals and maintaining a point of differentiation for brands that have already achieved them. REI rolls out rigorous new sustainability standards for suppliers 2018-04-09T04:00:00Z "And unfortunately, a lot of our evangelical religious right advocates have not made this differentiation." Inside the White House Bible Study group 2018-04-07T04:00:00Z Mitochondrial oxidative metabolism is required for the cardiac differentiation of stem cells. Advanced maturation of human cardiac tissue grown from pluripotent stem cells 2018-04-03T04:00:00Z This differentiation springs from a modification of the cells’ genetic programme: the switching on and off of genes. Why two brains are better than one 2018-03-31T04:00:00Z That said, I was surprised to stumble upon an apparent point of differentiation during the course of a conversation about childhood. Colleagues Think You’re Contagious. You’re Sure You’re Not. 2018-03-16T04:00:00Z Doing so can not only help organizations prepare for a crisis but also drive long-term value in brand equity, market differentiation, and future growth. John Skipper Says ESPN Exit Was Tied to Extortion Attempt by Cocaine Dealer 2018-03-15T04:00:00Z Ambrose, S. H. Late Pleistocene human population bottlenecks, volcanic winter, and differentiation of modern humans. Humans thrived in South Africa through the Toba eruption about 74,000 years ago 2018-03-11T05:00:00Z Much of the novel comes in a stream-of-consciousness style known as erlebte Rede, a cinematic barrage of impressions and thoughts recalled without explanation or differentiation. The real resonances, and warnings, of Weimar Germany 2018-03-08T05:00:00Z It was believed cell differentiation was one way – that once a cell was committed to a fate, there was no going back and that the silenced genes were switched off for ever. Why two brains are better than one 2018-03-31T04:00:00Z It will be particularly useful to dissect the extent to which external factors, including sensory signals from the peripheral nervous system, drive differentiation and further diversification of neurons within these genetically poised subtypes. A mixed model of neuronal diversity 2018-03-04T05:00:00Z Sequential transcriptional waves direct the differentiation of newborn neurons in the mouse neocortex. Developmental diversification of cortical inhibitory interneurons 2018-03-04T05:00:00Z Last month, Zaev said Macedonia was looking at four options to settle the dispute with Greece that would include a geographical “qualifier” to ensure differentiation between the two names. Macedonians protest against name change deal with Greece 2018-03-04T05:00:00Z High-precision data on variability in tungsten isotopes have shown that some of these domains resulted from differentiation events that occurred within the first fifty million years of Earth history3,4. Hadean silicate differentiation preserved by anomalous 142Nd/144Nd ratios in the Réunion hotspot source 2018-02-27T05:00:00Z While I obviously don’t share BlackBerry’s enthusiasm for the KeyOne’s market performance, I do see sufficient differentiation and remaining brand cachet to keep the brand going. BlackBerry declares ‘mission accomplished’ with KeyOne despite anemic sales 2018-02-26T05:00:00Z Because the flooding, the weird weather, the huge differentiations in temperature: they’re all there. John Scalzi’s The Consuming Empire is a space opera about climate change denialism 2018-02-12T05:00:00Z Basically, there’s not a ton of differentiation in this market right now, but it means there are a lot of options for schools. Dell’s Chromebook 5190 has USB-C and stylus support 2018-01-25T05:00:00Z This study was one of the first to provide evidence of an HSC differentiation bias along the megakaryocyte–platelet lineage. From haematopoietic stem cells to complex differentiation landscapes 2018-01-23T05:00:00Z The data correlate with helium isotopic data, suggesting parallel behaviour of the isotopic systems during silicate differentiation, perhaps as early as 4.39 billion years ago. Hadean silicate differentiation preserved by anomalous 142Nd/144Nd ratios in the Réunion hotspot source 2018-02-27T05:00:00Z Segmented filamentous bacteria antigens presented by intestinal dendritic cells drive mucosal TH17 cell differentiation. Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism 2018-01-21T05:00:00Z Phylogenetic differentiation of the Osprey Pandion haliaetus inferred from nucleotide sequences of the mitochondrial cytochrome b gene. Raptors Once More (Raptors, Part 2) 2018-01-21T05:00:00Z But there may be a little more of a physical differentiation for much of the second season. Oscar winner J.K. Simmons on his long career and pulling double duty in the new Starz thriller 'Counterpart' 2018-01-20T05:00:00Z Long-term propagation of distinct hematopoietic differentiation programs in vivo. From haematopoietic stem cells to complex differentiation landscapes 2018-01-23T05:00:00Z Upside-down differentiation and generation of a ‘primordial’ lower mantle. Hadean silicate differentiation preserved by anomalous 142Nd/144Nd ratios in the Réunion hotspot source 2018-02-27T05:00:00Z That differentiation, presumably, being through services that couldn’t be offered before because they violated net neutrality. ISPs won’t promise to treat all traffic equally after net neutrality 2017-12-15T05:00:00Z Using computational and pooled in vivo RNA interference screens, we identify the transcription factor Runx3 as a key regulator of TRM cell differentiation and homeostasis. Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours 2017-12-05T05:00:00Z These cycles of differentiation and morphogenesis are key to normal development — but how do embryos coordinate them? Early embryos kept in check This study demonstrates that the structure of the haematopoietic hierarchy and the differentiation journeys downstream of HSCs change over a human lifetime. From haematopoietic stem cells to complex differentiation landscapes 2018-01-23T05:00:00Z This differentiation continued even into the Old City. Perspective | No, Trump didn’t end the peace process by recognizing Jerusalem 2017-12-08T05:00:00Z I grew up in a working class town in the midwest with very little income differentiation between black and whites and a completely integrated school system. Opinion | An Abomination. A Monster. That’s Me? 2017-12-09T05:00:00Z In vivo RNA interference screens identify regulators of antiviral CD4+ and CD8+ T cell differentiation. Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours 2017-12-05T05:00:00Z Regular surpluses enabled a much greater degree of role differentiation within farming societies, creating space for less immediately productive roles. How Neolithic farming sowed the seeds of modern inequality 10,000 years ago 2017-12-05T05:00:00Z A single cell resolution map of mouse haematopoietic stem and progenitor cell differentiation. From haematopoietic stem cells to complex differentiation landscapes 2018-01-23T05:00:00Z Volatile element delivery and retention played a fundamental part in Earth’s formation and subsequent chemical differentiation. Halogens in chondritic meteorites and terrestrial accretion 2017-11-28T05:00:00Z And in a culture and society in which the manority readily accepts stark class differentiation, there is no need for a blacksheep minority group. In Myanmar, Pope Francis Calls for Peace Without Saying ‘Rohingya’ 2017-11-28T05:00:00Z However, the molecular signals that control TRM cell differentiation and homeostasis are not fully understood. Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours 2017-12-05T05:00:00Z We observe up to tenfold differences in the microbial loads of healthy individuals and relate this variation to enterotype differentiation. Quantitative microbiome profiling links gut community variation to microbial load 2017-11-14T05:00:00Z This study provides evidence that differentiation biases of HSCs change over a lifetime. From haematopoietic stem cells to complex differentiation landscapes 2018-01-23T05:00:00Z “To maintain an appropriate level of differentiation is a black art,” Mr. Wells said. Opel’s New Owner Vows to Make What General Motors Couldn’t: Money 2017-11-09T05:00:00Z "Head-to-head victories among comparable teams, results against common opponents and strength of schedule remain important points of differentiation for many teams." Alabama back on top of playoff picture, motivated by a bad memory, and that spells trouble for everyone else – LA Times 2017-11-14T05:00:00Z Epigenetic landscapes reveal transcription factors that regulate CD8+ T cell differentiation. Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours 2017-12-05T05:00:00Z Monod, J. The phenomenon of enzymatic adaptation and its bearings on problems of genetics and cellular differentiation. A global resource allocation strategy governs growth transition kinetics of Escherichia coli 2017-10-24T04:00:00Z Hierarchical folding and reorganization of chromosomes are linked to transcriptional changes in cellular differentiation. Two independent modes of chromatin organization revealed by cohesin removal 2017-09-26T04:00:00Z “That’s where you find the most innovation and differentiation,” she said. Focused Bets on Growth Propel Three Stock Funds 2017-10-13T04:00:00Z In a next step, Volkswagen will pursue greater differentiation between its premium brands and expand the strategy to other regions, Mueller said, without being more specific. Volkswagen to make brands more distinct to boost efficiency 2017-10-12T04:00:00Z At a recent group executive committee meeting, Diess called for greater differentiation between VW and Skoda target markets and clientele, particularly for future electric models, three managers with knowledge of the matter said. Exclusive: VW seeks to curb competition from Skoda - sources 2017-10-04T04:00:00Z If you've ever fumbled on the couch without your glasses for the Apple TV remote and found yourself holding it upside-down, you appreciate the new tactile differentiation. Review | The new Apple TV 4K finally catches up to its competitors 2017-09-21T04:00:00Z It’s tough to predict where he will sign, especially since the differentiation within signing bonuses will be so small because of MLB’s nonsensical rules, but they are certainly not a favorite. Angels mailbag: Looking at the last two weeks 2017-09-18T04:00:00Z Some also question whether content differentiation will provide a long-term advantage. David v Goliath: Deezer seeks musical edge on Spotify 2017-09-11T04:00:00Z In a next step, Volkswagen will pursue greater differentiation between its premium brands and expand the strategy to other regions, Mueller said, without being more specific. Volkswagen to make brands more distinct to boost efficiency 2017-10-12T04:00:00Z At a recent group executive committee meeting, Diess called for greater differentiation between VW and Skoda target markets and clientele, particularly for future electric models, three managers with knowledge of the matter said. Exclusive: VW seeks to curb competition from Skoda - sources 2017-10-04T04:00:00Z Hollander intends to keep the Pacific Coast Feather brand — “we’re proud of that brand,” Eichhorn said — as well as the differentiation between the Hollander and Pacific Coast brands. Seattle jobs at Pacific Coast Feather cut sharply after sale to Hollander 2017-09-04T04:00:00Z Elsewhere, however, margins are probably rising as a result of product differentiation and personalisation. Market concentration can benefit consumers, but needs scrutiny 2017-08-31T04:00:00Z Some also question whether content differentiation will provide a long-term advantage. David v Goliath: Deezer seeks musical edge on Spotify 2017-09-11T04:00:00Z The aim of the new grading system, which currently only applies to these three key subjects, is to allow more differentiation between the brightest candidates. I am in shock, says student with three grade 9s - BBC News 2017-08-24T04:00:00Z “This was an expression of opposition to the campaign rhetoric of Trump at the time and an expression of Canadian differentiation,” Lorne Sossin, dean of York University’s Osgoode Hall Law School. Canadian Judge Faces Possible Discipline for Wearing Trump Cap 2017-08-23T04:00:00Z Get reliability right, and few of us will complain about the lack of extra features or differentiation. Samsung’s Galaxy Note 8 faces one low, but unconditional expectation 2017-08-23T04:00:00Z To understand why variations in the gene MYC and its relatives lead to childhood brain tumors, Knoepfler realized he would have to detail their normal role in the growth and differentiation of neural stem cells. The rise of unproven stem cell therapies turned this obscure scientist into an industry watchdog 2017-08-03T04:00:00Z The best leaders teach their team and their entire organization to drive differentiation of talent, and they reward difference-makers. Why “servant leaders” are so effective 2017-07-22T04:00:00Z It’s a small point of differentiation, but it’s an important one as original content continues to be such a vital part of the long-term strategy of all streaming services. Netflix is bringing Dolby Atmos surround sound to its original content starting with Okja 2017-06-28T04:00:00Z “We used a center beam aesthetically to hide the differentiation,” Ellen says — “and we used track lighting.” A Bellevue family transforms a 1954 home while leaving its street face intact 2017-06-09T04:00:00Z “Different architecture on each parcel allowed more differentiation of the project and I think it’s more interesting.” Southwest Waterfront, already Washington’s biggest new development, will double in size 2017-05-17T04:00:00Z “It's a technology to allow us to actually screen the compounds that induce the differentiation that we want to see in people.” Therapeutic developments: Masters of medicine : Nature : Nature Research 2017-05-16T04:00:00Z But because we were really focused on the product differentiations between us and the competition, it didn’t afford us the ability to really tell our story. An Advertising Shift At Lyft: Not So Much About Uber 2017-05-17T04:00:00Z Israel vehemently protests against this policy of so-called differentiation between Israel and the occupied territories, believing that it delegitimises the settlements and the state, and could lead to boycotts and sanctions of the country. Israel-Palestine: the real reason there’s still no peace 2017-05-16T04:00:00Z “If there’s no sufficient differentiation of voices, they may be forced to divest,” Amobi said. Sale of Tribune to Sinclair could put KOMO, KCPQ under same broadcast giant 2017-05-08T04:00:00Z Hair was a big thing for Jeffrey, his point of differentiation, the “this is me” moment that many men have traditionally alighted on when they adapt publicly into a chosen gay identity. 30 years of gay style: from disco chic to hipster bears 2017-04-25T04:00:00Z The mechanism of action of this tumour suppressor involves, in part, alterations in mitochondrial lipid metabolism, which are accompanied by differentiation of cancer cells and loss of tumorigenicity. LACTB is a tumour suppressor that modulates lipid metabolism and cell state : Nature : Nature Research 2017-03-21T04:00:00Z This DNA hypermethylation leads to changes in gene expression that promote the proliferation of long-lived TET2-mutant haematopoietic stem cells, and disrupt their differentiation into various types of blood cell, thereby promoting AML. Cancer therapy: The leukaemia epigenome targeted : Nature : Nature Research 2017-03-28T04:00:00Z What supporters of differentiation commonly reject, however, is no less important. Israel-Palestine: the real reason there’s still no peace 2017-05-16T04:00:00Z The new status of the river means if someone abused or harmed it the law now sees no differentiation between harming the tribe or harming the river because they are one and the same. New Zealand river granted same legal rights as human being 2017-03-16T04:00:00Z “The rule thus treats all employees to the undertaking in the same way, notably by requiring them, generally and without any differentiation, to dress neutrally.” Islamic headscarves, ‘visible signs’ of religion can be banned by employers, EU top court rules 2017-03-14T04:00:00Z Post-mitotic, differentiated cells exhibit a variety of characteristics that contrast with those of actively growing neoplastic cells, such as the expression of cell-cycle inhibitors and differentiation factors. LACTB is a tumour suppressor that modulates lipid metabolism and cell state : Nature : Nature Research 2017-03-21T04:00:00Z The impression given by this differentiation between us is that I use a guitar to facilitate my songwriting needs while Tim really knows how to play his axe. Cate Le Bon: ‘Guitars were inspired by female bodies. Why are they uncomfortable for women to play?’ 2017-01-26T05:00:00Z "We are profiting from the other regions, and the other regions are profiting from us. It's a functional differentiation." Davos 2017: Is the urban-rural divide increasing? - BBC News 2017-01-17T05:00:00Z Clearest differentiation was found in the plastid network, with four distinct haplotype groups each separated from each other by at least 20 substitutions. Genome sequence and genetic diversity of European ash trees : Nature : Nature Research 2016-12-25T05:00:00Z But, he added: "Populism is based on a dichotomy, on a differentiation between the people and the elite." Populism: Pantomime politics or the public fighting back? - BBC News 2016-12-28T05:00:00Z Its mechanism of action involves alteration of mitochondrial lipid metabolism and differentiation of breast cancer cells. LACTB is a tumour suppressor that modulates lipid metabolism and cell state : Nature : Nature Research 2017-03-21T04:00:00Z And the differentiation between Israel proper and the settlements signaled that unlike in the past, Israel was no longer being forced to defend its right to exist. A Humbled Netanyahu Places Hopes in Trump 2016-12-25T05:00:00Z As one of his friends put it, “The problem with shooting from an airplane is that there is less differentiation in point of view. There is a danger of falling into a formula.” Edward Burtynsky’s Epic Landscapes 2016-12-11T05:00:00Z In order to find genomic regions for which genetic differentiation is correlated with the timing differences between strains, the Mantel test was then applied to 5-kb genomic windows every 1 kb along the reference sequence. The genomic basis of circadian and circalunar timing adaptations in a midge : Nature : Nature Research 2016-11-20T05:00:00Z “More and more, it’s going to be that compute capability that’s going to drive a lot of the differentiation of the car of the future.” Intel Courts Auto Industry as Battle Brews to Provide Autonomous-Car Computing Power 2016-11-15T05:00:00Z Medium was changed every 3 days and differentiation occurred around days 4–6. LACTB is a tumour suppressor that modulates lipid metabolism and cell state : Nature : Nature Research 2017-03-21T04:00:00Z However, I was disturbed by the differentiation in the article between “psychiatric” and “medical” patients. For patients with mental illness, a stigma reinforced 2016-10-28T04:00:00Z You would want a balance between tightness and differentiation. Premier League vulnerabilities add to the intrigue among a putative Big Six | Jonathan Wilson 2016-10-28T04:00:00Z “There’s not a big differentiation in our group right now,” he said. Smarting from upset, Buckeyes face improved Northwestern 2016-10-28T04:00:00Z The fingerprint sensor does not appear to be part of the touchscreen, however, with a second image showing a subtle differentiation between the two parts of the computer. Apple leaks images that apparently show new MacBook Pro 2016-10-26T04:00:00Z "We think it's more crucial to focus on quality differentiation to survive instead of adjusting production, even though it contributes to a glut," said Park. Amid fried chicken craze, foreign firms ruffle Korean feathers 2016-10-15T04:00:00Z Korman’s point of differentiation is selling fragrance tied to a specific mood or story — not by ingredients. Like Warby Parker did with eyewear, direct-to-consumer fragrance labels are gaining followers 2016-10-10T04:00:00Z "The financial advisor has to ask themself the question: 'What is my differentiation to my customer? How will I be a better financial advisor to my customer?'" How Will Robo Advisors Impact the Future of Investing? 2016-09-29T04:00:00Z "Crowd-sourced data is crucial for live traffic/maps and the size of the user base will be key to differentiation," UBS said in a recent report. HERE, automakers team up to share data on traffic conditions 2016-09-25T04:00:00Z Unsurprisingly, a culture that legitimizes this stark differentiation between the haves and have-nots of further education has arisen. Life in academic poverty as an underpaid university teacher: “They just don’t want to pay” 2016-09-24T04:00:00Z It led to a differentiation between skilled non-manual occupations and skilled manual occupations. End class wars 2016-09-20T04:00:00Z Firstly, of Phil Schiller’s 10 points of differentiation for iPhone 7, I’m taking the last one and pulling it forward: performance. The iPhone is still a fundamentally superb phone 2016-09-08T04:00:00Z Education politics means productivity and meaningful kinds of differentiation among teachers remains a mostly off-limits conversation. Written Off 2016-09-01T04:00:00Z But directing these cells to become muscle, bone or skin -- a process known as differentiation -- requires lengthy steps, according to the researchers. In Mice, a Way for Stem Cells to Build Bone 2016-08-31T04:00:00Z "The differentiation between resource economies is whether the countries have made sound fiscal reform in the boom years," Lele says. Why Resource-Rich Economies Are Really Cursed 2016-08-30T04:00:00Z “There is very little differentiation between four legs and two legs.” Here Are 10 Hero Dogs to Celebrate on National Dog Day 2016-08-25T04:00:00Z "When we think about genetic differentiation, we imagine animal species that are separated by large distances will be genetically different from one another." Meet the Rare Swimming Wolves That Eat Seafood This deal also gives VZ some differentiation from its biggest competitors, AT&T, Sprint Corp. Yahoo Acquisition Is a Smart Move for Verizon Communications (YHOO, VZ) 2016-07-22T04:00:00Z Innovation and differentiation—the creation of things new and singular—are a boon to economic progress and the bane of economic measurement. Patty-purchasing parity 2016-07-21T04:00:00Z Neatly compressing findings in ethology, economics and more, he looks at imitation, differentiation, motivation and the see-saw between novelty and familiarity. Books in brief : Nature : Nature Research 2016-07-19T04:00:00Z Live-streaming would be a major point of differentiation for the Hero 5, because — right now, at least — none of GoPro’s major competition offers that feature. The future of GoPro's hardware should be all about live-streaming 2016-07-18T04:00:00Z Instead, the company equips them all with the same battery pack and limits the output on some to create differentiation. Tesla releases a cheaper version of the Model X SUV 2016-07-13T04:00:00Z She attributed the lack of activity along the Midtown corridor to oversupply, little differentiation among glassy ultraluxury units and peak pricing. In New York, a Falling Market for Trophy Homes in the Sky 2016-07-11T04:00:00Z ILC3s contribute to the differentiation of T cells and B cells. The microbiota in adaptive immune homeostasis and disease : Nature : Nature Publishing Group 2016-07-05T04:00:00Z "It is critical that you make that differentiation," he says. 6 Facts to Know Before Investing in a Restaurant 2016-06-29T04:00:00Z Perhaps some ingrained sense of the evolutionary utility of this differentiation explains why humans are so torn between wanting to belong to a group and wanting to be distinct individuals. The secret of taste: why we like what we like | Tom Vanderbilt 2016-06-22T04:00:00Z Ulta’s main point of differentiation from the others is its mix of both prestige and mass brands. A Beauty Retailer That Knows What You Want 2016-06-21T04:00:00Z Laplane defines a stem cell as one “capable of self-renewal and of differentiation”, where self-renewal is the ability to recreate one copy of itself on division. Cancer therapy: Defining stemness : Nature : Nature Publishing Group 2016-06-07T04:00:00Z It is unclear whether constituents of the microbiota or other environmental factors direct the differentiation of naive CD4+ T cells into homeostatic or pathogenic TH17 cells. The microbiota in adaptive immune homeostasis and disease : Nature : Nature Publishing Group 2016-07-05T04:00:00Z If only for purposes of product differentiation, they are sure to be unique and memorable. When Products Talk 2016-06-01T04:00:00Z |
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