英语词汇“degrader”造句子简单的方法、技巧、例句及翻译-英语例句辞典

"Targeting TC-PTP with the small-molecule degraders represents an alternative approach to increase tumor antigen presentation and alleviate the inhibitory constraints on immune cells in the tumor microenvironment for improved immunotherapy," he said. Pharmaceutical compound sounds the alarm on cancer cells and unleashes T cells 2023-11-14T05:00:00Z

"By isolating the first taurine degrader in the mouse gut, we're one step closer to understanding how these gut microbes mediate animal and human health" explains Huimin Ye, lead author of the study. That smell: New gut microbe produces smelly toxic gas but protects against pathogens 2023-09-18T04:00:00Z

Eighteen such protein degraders are in or nearing clinical trials, according to an April analysis in Nature Reviews Drug Discovery. Protein-destroying compounds take aim at disease molecules outside cells 2021-08-31T04:00:00Z

One such approach uses drug molecules called protein degraders, which promote the tagging of proteins with ubiquitin, another small protein. New class of molecule targets proteins outside cells for degradation 2020-07-28T04:00:00Z

Crews wasn’t the only one chasing protein degraders. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z

"We will continue to improve the potency and drug properties of the TP1L and expand its utility of the degraders on different cancers," Zhang said. Pharmaceutical compound sounds the alarm on cancer cells and unleashes T cells 2023-11-14T05:00:00Z

She found that the presence of an unnamed bacterium, closely related to a known tannin degrader, Lonepinella koalarum, was a significant factor in whether a koala survives antibiotic treatment. As Koalas Suffer From Chlamydia, A New Clue For Treatment 2018-04-14T04:00:00Z

That can give degraders longer lasting impact and potentially allow them to disable “undruggable” proteins by binding anywhere on the molecule, rather than having to target an active site. Protein-destroying compounds take aim at disease molecules outside cells 2021-08-31T04:00:00Z

But because the ubiquitin-mediated degradation pathway occurs inside the cell, protein degraders developed so far attack mainly intracellular targets. New class of molecule targets proteins outside cells for degradation 2020-07-28T04:00:00Z

On its website, the company says that injecting its tau-protein degrader directly into the mouse hippocampus reduced levels of tau by 50%. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z

Antiprotons are delivered in bunches by the Antiproton Decelerator of CERN; the antiproton bunches also release hydrogen from our degrader structure. High-precision comparison of the antiproton-to-proton charge-to-mass ratio : Nature : Nature Publishing Group 2015-08-11T04:00:00Z

It's a glorious field," said Blair, stretching out his arms energetically as though to gather it all in at once, "if we can only occupy it and fence it round before the degraders come. White Fire 2011-11-21T03:00:15.067Z

With the new methods, those proteins, too, are becoming viable targets for degraders. Protein-destroying compounds take aim at disease molecules outside cells 2021-08-31T04:00:00Z

The development of lysosomal degraders that are smaller and less polar than LYTACs — and therefore more able to pass through membranes — will be eagerly anticipated. New class of molecule targets proteins outside cells for degradation 2020-07-28T04:00:00Z

Various teams are also working to expand the pool of ligases that protein degraders can recruit. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z

Whilst women suffer in every respect from the influence of alcohol as a degrader of their men, most of all do they and the race suffer through the action of alcohol upon the racial instinct. Woman and Womanhood A Search for Principles

But formal religionists, inflamed by religious animosity, are often the degraders of religion for the gratification of their hatred. Expositions of Holy Scripture: St. John Chaps. XV to XXI

Those be mere vintage-leavings, jabberers, choirs Of swallow-broods, degraders of their art, Who get one chorus, and are seen no more, The Muses' love once gained. The Frogs

Is no protein beyond the reach of degraders? New class of molecule targets proteins outside cells for degradation 2020-07-28T04:00:00Z

That’s crucial because there has been considerable doubt about whether protein degraders can work in humans. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z

Buoyed by fresh targets, improved potency, and a clinical trial about to begin, researchers are ready to prove that protein degraders can be more than a parlour trick. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z

The protein degraders worked both in cells in a dish and in human tumours in mice. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z

单词	degrader
例句	degrader "Targeting TC-PTP with the small-molecule degraders represents an alternative approach to increase tumor antigen presentation and alleviate the inhibitory constraints on immune cells in the tumor microenvironment for improved immunotherapy," he said. Pharmaceutical compound sounds the alarm on cancer cells and unleashes T cells 2023-11-14T05:00:00Z "By isolating the first taurine degrader in the mouse gut, we're one step closer to understanding how these gut microbes mediate animal and human health" explains Huimin Ye, lead author of the study. That smell: New gut microbe produces smelly toxic gas but protects against pathogens 2023-09-18T04:00:00Z Eighteen such protein degraders are in or nearing clinical trials, according to an April analysis in Nature Reviews Drug Discovery. Protein-destroying compounds take aim at disease molecules outside cells 2021-08-31T04:00:00Z One such approach uses drug molecules called protein degraders, which promote the tagging of proteins with ubiquitin, another small protein. New class of molecule targets proteins outside cells for degradation 2020-07-28T04:00:00Z Crews wasn’t the only one chasing protein degraders. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z "We will continue to improve the potency and drug properties of the TP1L and expand its utility of the degraders on different cancers," Zhang said. Pharmaceutical compound sounds the alarm on cancer cells and unleashes T cells 2023-11-14T05:00:00Z She found that the presence of an unnamed bacterium, closely related to a known tannin degrader, Lonepinella koalarum, was a significant factor in whether a koala survives antibiotic treatment. As Koalas Suffer From Chlamydia, A New Clue For Treatment 2018-04-14T04:00:00Z That can give degraders longer lasting impact and potentially allow them to disable “undruggable” proteins by binding anywhere on the molecule, rather than having to target an active site. Protein-destroying compounds take aim at disease molecules outside cells 2021-08-31T04:00:00Z But because the ubiquitin-mediated degradation pathway occurs inside the cell, protein degraders developed so far attack mainly intracellular targets. New class of molecule targets proteins outside cells for degradation 2020-07-28T04:00:00Z On its website, the company says that injecting its tau-protein degrader directly into the mouse hippocampus reduced levels of tau by 50%. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z Antiprotons are delivered in bunches by the Antiproton Decelerator of CERN; the antiproton bunches also release hydrogen from our degrader structure. High-precision comparison of the antiproton-to-proton charge-to-mass ratio : Nature : Nature Publishing Group 2015-08-11T04:00:00Z It's a glorious field," said Blair, stretching out his arms energetically as though to gather it all in at once, "if we can only occupy it and fence it round before the degraders come. White Fire 2011-11-21T03:00:15.067Z With the new methods, those proteins, too, are becoming viable targets for degraders. Protein-destroying compounds take aim at disease molecules outside cells 2021-08-31T04:00:00Z The development of lysosomal degraders that are smaller and less polar than LYTACs — and therefore more able to pass through membranes — will be eagerly anticipated. New class of molecule targets proteins outside cells for degradation 2020-07-28T04:00:00Z Various teams are also working to expand the pool of ligases that protein degraders can recruit. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z Whilst women suffer in every respect from the influence of alcohol as a degrader of their men, most of all do they and the race suffer through the action of alcohol upon the racial instinct. Woman and Womanhood A Search for Principles But formal religionists, inflamed by religious animosity, are often the degraders of religion for the gratification of their hatred. Expositions of Holy Scripture: St. John Chaps. XV to XXI Those be mere vintage-leavings, jabberers, choirs Of swallow-broods, degraders of their art, Who get one chorus, and are seen no more, The Muses' love once gained. The Frogs Is no protein beyond the reach of degraders? New class of molecule targets proteins outside cells for degradation 2020-07-28T04:00:00Z That’s crucial because there has been considerable doubt about whether protein degraders can work in humans. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z Buoyed by fresh targets, improved potency, and a clinical trial about to begin, researchers are ready to prove that protein degraders can be more than a parlour trick. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z The protein degraders worked both in cells in a dish and in human tumours in mice. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z
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