| 单词 | aldosterone |
| 例句 | The main mineralocorticoid is aldosterone, which regulates the concentration of ions in urine, sweat, and saliva. Concepts of Biology 2013-04-25T00:00:00Z What is the probable mechanism of action of aldosterone? Biology for AP Courses 2022-06-09T00:00:00Z The adrenal cortex directly influences renal function through the production of the hormone aldosterone to stimulate sodium reabsorption. Anatomy and Physiology 2013-06-19T00:00:00Z PA is caused by a surfeit of aldosterone, a hormone produced by the adrenal glands. Despite a ‘bucketload’ of drugs, his blood pressure was perilously high 2022-04-23T04:00:00Z They've called on clinicians to increase their vigilance and more readily prescribe drugs that block aldosterone's effects. Doctors overlook a curable cause of high blood pressure 2022-02-26T05:00:00Z Another adrenal hormone, aldosterone, controls sodium levels, and through that, blood pressure. She Craved Salt and Felt Nauseated for Months. What Was Wrong? 2020-09-30T04:00:00Z They secrete cortisol and aldosterone, which increase heart rate, breathing rate, muscle contractions, blood pressure, and blood glucose as short-term stress response. Biology for AP Courses 2022-06-09T00:00:00Z When aldosterone decreases, more Na+ remains in the forming urine and more K+ is recovered in the circulation. Anatomy and Physiology 2013-06-19T00:00:00Z Excess aldosterone can cause the kidneys to retain sodium and lose potassium, which raises blood pressure. Despite a ‘bucketload’ of drugs, his blood pressure was perilously high 2022-04-23T04:00:00Z If one gland is secreting excess aldosterone, removing that gland may cure or improve the disease. Doctors overlook a curable cause of high blood pressure 2022-02-26T05:00:00Z She was started on two medications: hydrocortisone, to replace the cortisol, and Florinef, to replace the aldosterone. She Craved Salt and Felt Nauseated for Months. What Was Wrong? 2020-09-30T04:00:00Z They secrete cortisol and aldosterone, which increase heart rate, breathing rate, muscle contractions, blood pressure, and blood glucose as long-term stress response. Biology for AP Courses 2022-06-09T00:00:00Z The rise in pressure is sustained by the aldosterone effects initiated by angiotensin II; this includes an increase in Na+ retention and water volume. Anatomy and Physiology 2013-06-19T00:00:00Z The disease can be detected by blood tests that measure the levels of aldosterone and renin, an enzyme made in the kidneys that helps control blood pressure, then calculating the ratio between the two. Despite a ‘bucketload’ of drugs, his blood pressure was perilously high 2022-04-23T04:00:00Z The authors wrote that ARR "can be a simple and useful screening method" but cautioned against overreliance, noting that arbitrarily high cutoff values and aldosterone's tendency to fluctuate likely contribute to underdiagnosis. Doctors overlook a curable cause of high blood pressure 2022-02-26T05:00:00Z They take strong medications – ACE inhibitors, beta-blockers and aldosterone antagonists – to forestall the disease process. Congestive Heart Failure: When It’s Time to Talk Transplant 2015-04-01T04:00:00Z These hormones go one step further and trigger the renin-angiotensin- aldosterone system. Biology for AP Courses 2022-06-09T00:00:00Z Due to its structural similarity to aldosterone, progesterone binds to the aldosterone receptor in the collecting duct of the kidney, causing the same, albeit weaker, effect on Na+ and water retention. Anatomy and Physiology 2013-06-19T00:00:00Z Blood tests of Meredith’s levels of plasma renin, an enzyme that regulates blood pressure and kidney function, and aldosterone, a hormone produced in the adrenal gland, were abnormally low. Medical Mysteries: It seemed like a heart attack, but the tests said no. 2015-01-26T05:00:00Z Although Conn and others postulated that rogue aldosterone production is a common cause of hypertension, it took until the 1980s for diagnostic advances to confirm their hunch. Doctors overlook a curable cause of high blood pressure 2022-02-26T05:00:00Z People with the condition also release a hormone called aldosterone, which causes the body to retain fluid. Heart Failure: a Promising New Drug on the Horizon 2015-01-13T05:00:00Z Almost all of the sodium in the blood is reclaimed by the renal tubules under the influence of aldosterone. Biology for AP Courses 2022-06-09T00:00:00Z The adrenal glands produce the steroid hormone aldosterone, which is involved in osmoregulation, and cortisol, which plays a role in metabolism. Anatomy and Physiology 2013-06-19T00:00:00Z Problem is, the adrenals also produce the hormone aldosterone, which helps regulate your body’s levels of fluid and electrolytes. How much water you need to drink 2014-05-25T04:00:00Z Greater focus on excess aldosterone could advance national progress on blood pressure control, which has stalled, according to the 2020 U.S. Doctors overlook a curable cause of high blood pressure 2022-02-26T05:00:00Z But the Barataria Bay dolphins did not show the expected cortisol or aldosterone increases, which the researchers measured via blood test taken aboard a research vessel. Dolphins exposed to Deepwater Horizon oil spill had more health problems than others 2014-03-03T21:50:30Z Because sodium is always reabsorbed by active transport and water follows sodium to maintain osmotic balance, aldosterone manages not only sodium levels but also the water levels in body fluids. Biology for AP Courses 2022-06-09T00:00:00Z In response, aldosterone increases the excretion of K+ and the retention of Na+, which in turn increases blood volume and blood pressure. Anatomy and Physiology 2013-06-19T00:00:00Z So as adrenal fatigue progresses, your body’s production of aldosterone drops, triggering dehydration and low electrolyte levels, he says. How much water you need to drink 2014-05-25T04:00:00Z Although that 48-page document, like much public health messaging, doesn't mention primary aldosteronism or aldosterone, it notes that only about one in four U.S. adults with hypertension has it under control. Doctors overlook a curable cause of high blood pressure 2022-02-26T05:00:00Z Both increase the amount of aldosterone made in an adrenal gland. Tiny growths 'raise blood pressure' 2013-08-05T07:16:35Z In contrast, absence of aldosterone means that no sodium gets reabsorbed in the renal tubules and all of it gets excreted in the urine. Biology for AP Courses 2022-06-09T00:00:00Z The adrenal glands also undergo changes as the body ages; as fibrous tissue increases, the production of cortisol and aldosterone decreases. Anatomy and Physiology 2013-06-19T00:00:00Z A gene duplication more than 450 million years ago produced the two receptors - but aldosterone didn't arise until many millions of years later. Biologist Resurrects Prehistoric Proteins 2012-03-21T20:15:00.223Z Both of her adrenal glands produce excess aldosterone, which means she is not a candidate for surgery, and she does not tolerate either available drug. Doctors overlook a curable cause of high blood pressure 2022-02-26T05:00:00Z Once aldosterone had evolved, the team proposed, evolution was able to take advantage of the existing receptor to control a new biological function — a process that Thornton termed molecular exploitation. Prehistoric proteins: Raising the dead 2012-03-21T18:20:44.057Z Patients who have Addison's disease have a failing adrenal cortex and cannot produce aldosterone. Biology for AP Courses 2022-06-09T00:00:00Z It is renin that starts a series of reactions, leading to the production of the vasoconstrictor angiotensin II and the salt-retaining steroid aldosterone. Anatomy and Physiology 2013-06-19T00:00:00Z Once aldosterone had evolved, the team proposed, evolution was able to take advantage of the existing receptor to control a new biological function - a process that Thornton termed molecular exploitation. Biologist Resurrects Prehistoric Proteins 2012-03-21T20:15:00.223Z Missed diagnoses pose additional dangers: Excess aldosterone is toxic to the heart, blood vessels, kidneys, and other organs. Doctors overlook a curable cause of high blood pressure 2022-02-26T05:00:00Z A gene duplication more than 450 million years ago produced the two receptors — but aldosterone didn't arise until many millions of years later. Prehistoric proteins: Raising the dead 2012-03-21T18:20:44.057Z Its actions suppress the actions of aldosterone, ADH, and renin. Biology for AP Courses 2022-06-09T00:00:00Z Hormonal imbalances involving ADH and aldosterone may also result in higher-than-normal sodium values. Anatomy and Physiology 2013-06-19T00:00:00Z Torcetrapib, for example, can increase levels of aldosterone, a hormone that can increase blood pressure, he said. Merck Drug for Cutting Cholesterol Is Promising 2010-11-18T06:25:00Z Renin is an enzyme produced by the kidneys that triggers a chain reaction that leads to aldosterone production. Doctors overlook a curable cause of high blood pressure 2022-02-26T05:00:00Z Angiotensin II functions as a hormone and then causes the release of the hormone aldosterone by the adrenal cortex, resulting in increased Na+ reabsorption, water retention, and an increase in blood pressure. Biology for AP Courses 2022-06-09T00:00:00Z Hormones like epinephrine, norepinephrine, renin-angiotensin, aldosterone, anti-diuretic hormone, and atrial natriuretic peptide help regulate the needs of the body as well as the communication between the different organ systems. Biology for AP Courses 2022-06-09T00:00:00Z Angiotensin II also signals an increase in the release of aldosterone from the adrenal cortex. Anatomy and Physiology 2013-06-19T00:00:00Z But the new study reported no significant differences in change in blood pressure or in aldosterone levels between the anacetrapib and placebo groups. Merck Drug for Cutting Cholesterol Is Promising 2010-11-18T06:25:00Z But in people with primary aldosteronism, aldosterone can be elevated even when renin is low. Doctors overlook a curable cause of high blood pressure 2022-02-26T05:00:00Z There are two main corticosteroids: glucocorticoids such as cortisol, and mineralocorticoids such as aldosterone. Biology for AP Courses 2022-06-09T00:00:00Z Different regions of the liver have specialized cells that respond to chemical messengers and hormones like epinephrine, renin, aldosterone, ADH, and ANP. Biology for AP Courses 2022-06-09T00:00:00Z Thus, aldosterone causes an increase in blood sodium levels and blood volume. Anatomy and Physiology 2013-06-19T00:00:00Z The main mineralocorticoid is aldosterone, which regulates the concentration of Na+ ions in urine, sweat, pancreas, and saliva. Biology for AP Courses 2022-06-09T00:00:00Z Usually both glands are affected, in which case surgery isn't recommended and patients take one of two drugs that block aldosterone. Doctors overlook a curable cause of high blood pressure 2022-02-26T05:00:00Z ANP also reduces the amounts of renin released by the kidneys and aldosterone released by the adrenal cortex, further preventing the retention of water. Biology for AP Courses 2022-06-09T00:00:00Z Different regions of the nephrons have specialized cells that respond to chemical messengers and hormones like epinephrine, renin, aldosterone, ADH, and ANP. Biology for AP Courses 2022-06-09T00:00:00Z This control is exerted directly by ADH and aldosterone, and indirectly by renin. Anatomy and Physiology 2013-06-19T00:00:00Z The renin-angiotensin-aldosterone system is one way that aldosterone release is controlled. Biology for AP Courses 2022-06-09T00:00:00Z They adrenal cortex produces renin, which affects aldosterone secretion by the kidneys. Biology for AP Courses 2022-06-09T00:00:00Z The kidneys produce renin, which affects aldosterone secretion by the adrenal cortex. Biology for AP Courses 2022-06-09T00:00:00Z Different regions of the kidneys have specialized cells that respond to chemical messengers and hormones like epinephrine, renin, aldosterone, ADH, and ANP. Biology for AP Courses 2022-06-09T00:00:00Z In addition to receptors for ADH, principal cells have receptors for the steroid hormone aldosterone. Anatomy and Physiology 2013-06-19T00:00:00Z They kidneys produce calcitrol, which affects aldosterone secretion by the adrenal cortex. Biology for AP Courses 2022-06-09T00:00:00Z Underproduction of ADH inhibits the release of aldosterone that would cause improper functioning of kidneys. Biology for AP Courses 2022-06-09T00:00:00Z Identify what aldosterone regulates, and explain how it is stimulated. Biology for AP Courses 2022-06-09T00:00:00Z Different regions of the nephrons have specialized cells that respond to chemical messengers and hormones like epinephrine, renin, aldosterone, ADH, and ANP. Biology for AP Courses 2022-06-09T00:00:00Z While ADH is primarily involved in the regulation of water recovery, aldosterone regulates Na+ recovery. Anatomy and Physiology 2013-06-19T00:00:00Z Describe how renin promotes release of ADH and aldosterone. Biology for AP Courses 2022-06-09T00:00:00Z Figure 20.19 Hormones Involved in Renal Control of Blood Pressure In the renin-angiotensin-aldosterone mechanism, increasing angiotensin II will stimulate the production of antidiuretic hormone and aldosterone. Anatomy and Physiology 2013-06-19T00:00:00Z Natriuretic hormones are antagonists to angiotensin II. They promote loss of sodium and water from the kidneys, and suppress renin, aldosterone, and ADH production and release. Anatomy and Physiology 2013-06-19T00:00:00Z Renin acts on angiotensin to directly stimulate the release of aldosterone and ADH. Biology for AP Courses 2022-06-09T00:00:00Z When aldosterone output increases, more Na+ is recovered from the forming urine and water follows the Na+ passively. Anatomy and Physiology 2013-06-19T00:00:00Z The mineralocorticoids, chiefly aldosterone, cause sodium and fluid retention, which increases blood volume and blood pressure. Anatomy and Physiology 2013-06-19T00:00:00Z Natriuretic hormones act by inhibiting aldosterone release and therefore inhibiting Na+ recovery in the collecting ducts. Anatomy and Physiology 2013-06-19T00:00:00Z As a result, renin has an immediate effect on blood pressure due to angiotensin II–stimulated vasoconstriction and a prolonged effect through Na+ recovery due to aldosterone. Anatomy and Physiology 2013-06-19T00:00:00Z Other steroid hormones include aldosterone and cortisol, which are released by the adrenal glands along with some other types of androgens. Biology for AP Courses 2022-06-09T00:00:00Z Additional renin increases production of the powerful vasoconstrictor angiotensin II. Angiotensin II, as discussed above, will also stimulate aldosterone production to augment blood volume through retention of more Na+ and water. Anatomy and Physiology 2013-06-19T00:00:00Z At the same time that aldosterone causes increased recovery of Na+, it also causes greater loss of K+. Anatomy and Physiology 2013-06-19T00:00:00Z Progesterone is a steroid that is structurally similar to aldosterone. Anatomy and Physiology 2013-06-19T00:00:00Z The major hormones influencing total body water are ADH, aldosterone, and ANH. Anatomy and Physiology 2013-06-19T00:00:00Z Another hormone responsible for maintaining electrolyte concentrations in extracellular fluids is aldosterone, a steroid hormone that is produced by the adrenal cortex. Biology for AP Courses 2022-06-09T00:00:00Z When aldosterone causes a recovery of Na+ in the nephron, a negative electrical gradient is created that promotes the secretion of K+ and Cl– into the lumen. Anatomy and Physiology 2013-06-19T00:00:00Z The major hormones regulating body fluids are ADH, aldosterone and ANH. Anatomy and Physiology 2013-06-19T00:00:00Z Mechanisms for controlling Na+ concentration in the blood include the renin–angiotensin–aldosterone system and ADH. Anatomy and Physiology 2013-06-19T00:00:00Z The kidneys work with the adrenal cortex, lungs, and liver in the renin–angiotensin–aldosterone system to regulate blood pressure. Anatomy and Physiology 2013-06-19T00:00:00Z Because it is produced in the cortex of the adrenal gland and affects the concentrations of minerals Na+ and K+, aldosterone is referred to as a mineralocorticoid, a corticosteroid that affects ion and water balance. Biology for AP Courses 2022-06-09T00:00:00Z The production of hormones, such as human growth hormone, cortisol, aldosterone, sex hormones, and the thyroid hormones, decreases with age. Anatomy and Physiology 2013-06-19T00:00:00Z Potassium participates in the exchange with sodium in the renal tubules under the influence of aldosterone, which also relies on basolateral sodium-potassium pumps. Anatomy and Physiology 2013-06-19T00:00:00Z |
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