| 单词 | chloroquine |
| 例句 | Injections had always scared me—whenever I had malaria, I prayed I would need to take Novalgin tablets instead of chloroquine injections. Purple Hibiscus 2003-10-01T00:00:00Z Prior to the 1960s a number of drugs, such as Atabrine and chloroquine, had been developed that effectively treated this illness. An American Plague: The True and Terrifying Story of the Yellow Fever Epidemic of 1793 2003-06-23T00:00:00Z She had gotten her chloroquine injections there the last time she had malaria, and the nurse had boiled water on a smoky kerosene stove. Purple Hibiscus 2003-10-01T00:00:00Z Chloroquine, chloroquine, I know it’s for malaria, But with chloroquine, I’ll begin to end hysteria. Style Invitational Week 1382: For us, it’s still Post Time — it’s our annual foal name contest 2020-04-30T04:00:00Z Your scientific jargon has no meaning, I told you all that matters is the spin Then Laura said one word to me last evening: It’s chloroquine! Style Invitational Week 1382: For us, it’s still Post Time — it’s our annual foal name contest 2020-04-30T04:00:00Z For example, there was a discussion about potentially new therapeutics, one of them being chloroquine, this malaria drug. CNN’s Sanjay Gupta on covering the coronavirus: ‘I think there is intrinsic value to hope’ 2020-04-13T04:00:00Z To try to bring her fever down, doctors gave her chloroquine – “not hydroxychloroquine,” she stresses, referring to the unproven treatment President Trump has been promoting. Rita Wilson on coronavirus and choloroquine: ‘I was so ill I could hardly stand’ 2020-04-17T04:00:00Z On March 28, the Food and Drug Administration granted emergency authorization to doctors to prescribe hydroxychloroquine and another antimalarial drug, chloroquine, to treat Covid. Vladimir Zelenko, 48, Dies; Promoted an Unfounded Covid Treatment 2022-07-01T04:00:00Z Most treatments, including chloroquine, are directed at the blood stage of the parasite, and so cannot prevent recurrence of the infection and its associated symptoms. Novel Malaria Treatment for Children Receives First Approval 2022-03-14T04:00:00Z In the early 20th century, chloroquine helped beat back the pathogen worldwide. Drug-resistant malaria is emerging in Africa. Is the world ready? 2022-01-30T05:00:00Z A wealth of evidence now shows that the malaria drugs hydroxychloroquine and chloroquine were not effective at treating Covid-19 and carried potential risks. ‘Magic’ Weight-Loss Pills and Covid Cures: Dr. Oz Under the Microscope 2021-12-26T05:00:00Z Antimicrobials are being misused outside of hospital settings, and drugs such as ivermectin and chloroquine are being used as unproven treatments, even with strong evidence that they do not benefit COVID-19 patients, she said. Misuse of antibiotics in pandemic building resistant bacteria, health agency warns 2021-11-18T05:00:00Z The agency last year also said hydroxychloroquine and chloroquine were unlikely to be effective in treating the coronavirus. Alaska doctors seek COVID-19 misinformation investigation 2021-11-15T05:00:00Z The children all got a single dose of tafenoquine and a course of chloroquine administered according to local or national guidelines for the treatment of the active blood stage infection. Novel Malaria Treatment for Children Receives First Approval 2022-03-14T04:00:00Z Then, about a decade after World War II, resistance to chloroquine surfaced along the Thailand-Cambodia border. Drug-resistant malaria is emerging in Africa. Is the world ready? 2022-01-30T05:00:00Z Sao Paulo state’s prosecutors’ office said Monday it is investigating Prevent Senior for allegedly researching chloroquine effects on COVID-19 patients without clearly letting them know they were part of a trial. Brazil doctors accuse health company of forcing chloroquine 2021-09-28T04:00:00Z It developed resistance to once potent drugs such as chloroquine in the 1950s and ’60s, leading to a surge in the world’s malaria burden. Drug-resistant malaria is gaining a foothold in Africa 2021-09-22T04:00:00Z He touted the supposed healing powers of the anti-malarial chloroquine long after scientists around the world had dismissed it as ineffective. UN rule may be hurdle for Brazil vaccine skeptic Bolsonaro 2021-09-16T04:00:00Z In combination with chloroquine, tafenoquine can deliver what scientists call a “radical cure.” Novel Malaria Treatment for Children Receives First Approval 2022-03-14T04:00:00Z "In retrospect, we know that chloroquine was used for many years after there was a huge resistance problem," said Rosenthal. Drug-resistant malaria is emerging in Africa. Is the world ready? 2022-01-30T05:00:00Z Bolsonaro praised Prevent Senior’s studies on chloroquine on his social media channels in April. Brazil doctors accuse health company of forcing chloroquine 2021-09-28T04:00:00Z Artemisinin-based combination therapies - known for short as ACTs - are recommended by the WHO against malaria, especially those types now resistant to chloroquine, which is one of the main drug treatments for the disease. Coronavirus: What do we know about the artemisia plant? 2021-08-11T04:00:00Z Wilson later said she was given chloroquine nine days into her illness, but didn’t like the “extreme” side effects. Chet Hanks goes on anti-vax rant. He remembers his parents battled COVID, right? 2021-08-10T04:00:00Z Mandetta said he was called to a meeting in the presidential palace where he saw a draft of the decree on the table aimed at expanding chloroquine’s use to include COVID-19 treatment. Ex-minister: Bolsonaro eyed decree on chloroquine for COVID 2021-05-04T04:00:00Z Haunted by the failure of chloroquine, though, researchers have remained on the lookout for signs that the malaria parasite is evolving to resist artemisinin or its partner drugs. Drug-resistant malaria is emerging in Africa. Is the world ready? 2022-01-30T05:00:00Z He suggested the trials by the health care company had shown patients taking chloroquine were spending seven days on ventilators, as compared to 14 days among those who didn’t. Brazil doctors accuse health company of forcing chloroquine 2021-09-28T04:00:00Z “The government was aware that it was prescribing chloroquine without any scientific evidence,” Mandetta said. Brazil COVID-19 inquiry told of Bolsonaro's blind faith in chloroquine 2021-05-04T04:00:00Z Last year, he faced intense inquiries from federal prosecutors—and received death threats—after he published work highlighting the health risks of giving the drug chloroquine to COVID-19 patients. ‘A hostile environment.’ Brazilian scientists face rising attacks from Bolsonaro’s regime 2021-04-07T04:00:00Z Earlier in the pandemic, he also tweeted a positive opinion about chloroquine, an antimalarial drug, as an anti-COVID treatment. Column: Feds rule that Musk and Tesla are no friend to workers 2021-03-26T04:00:00Z "And try very, very hard" to make sure "that it's not going to be the same as when we had chloroquine resistance in Africa." Drug-resistant malaria is emerging in Africa. Is the world ready? 2022-01-30T05:00:00Z There’s now a wealth of evidence that the malaria drugs hydroxychloroquine and chloroquine did not work against Covid. How the Search for Covid-19 Treatments Faltered While Vaccines Sped Ahead 2021-01-30T05:00:00Z The following month, the Food and Drug Administration withdrew its emergency use authorization for hydroxychloroquine and chloroquine, drugs that Trump had repeatedly promoted for treatment of covid-19. ‘I do regret being there’: Simone Gold, noted hydroxychloroquine advocate, was inside the Capitol during the riot 2021-01-12T05:00:00Z He’s accused doctors of inflating case numbers for financial reasons, promoted a widely discredited paper on the benefits of chloroquine, called shelter-in-place orders “fascist,” and dismissed panic associated with the pandemic as “dumb.” Elon Musk says he’s tested positive (and negative) for COVID-19 2020-11-13T05:00:00Z During the pandemic, two successive health ministers resigned in roughly the span of a month, in part because as physicians, themselves, they would not fully endorse chloroquine. Brazil health minister hospitalized with COVID-19 2020-10-31T04:00:00Z Hydroxychloroquine and chloroquine are approved to treat autoimmune diseases like lupus as well as malaria. Trump Vaccine Chief Casts Doubt on Coronavirus Vaccine by Election Day 2020-09-03T04:00:00Z But the president is perhaps best known for his early and ardent embrace of the malaria drugs hydroxychloroquine and chloroquine. Trump pushes for COVID-19 treatments, claims slowdown at FDA 2020-08-23T04:00:00Z The FDA granted emergency approval in March for hydroxychloroquine and chloroquine to be used to treat COVID-19, but it revoked that authorization after finding them ineffective. Trump tears into FDA, speculates ‘deep state’ delaying coronavirus vaccine until after election 2020-08-22T04:00:00Z But chloroquine did not prove effective in clinical trials, and scientists discovered that it does not inhibit the virus in lung cells that express TMPRSS215. Progress report on the coronavirus pandemic 2020-08-18T04:00:00Z Hospitals are giving chloroquine to people with COVID-19, at the recommendation of the Brazilian ministry of health, even though evidence now suggests it does not help and may even be harmful. ‘The Biggest Monster’ Is Spreading. And It’s Not the Coronavirus. 2020-08-03T04:00:00Z "Upon the effective date of this rule, all previous approvals for the use of chloroquine or hydroxychloroquine shall be deemed void and must be approved using the process outlined in this paragraph." Hydroxychloroquine banned by Ohio pharmacy board for coronavirus treatment 2020-07-29T04:00:00Z Multiple studies have disputed claims that antimalarial and antiviral drugs such as hydroxychloroquine and chloroquine and the antibiotic azithromycin can help treat or even prevent the coronavirus. Twitter penalizes Donald Trump Jr. for posting hydroxychloroquine misinformation amid coronavirus pandemic 2020-07-28T04:00:00Z Multiple studies have disputed claims that antimalarial and antiviral drugs like hydroxychloroquine, azithromycin, and chloroquine can help treat or even prevent coronavirus. Facebook deleted a viral video full of false coronavirus claims. Then Trump shared it on Twitter. 2020-07-28T04:00:00Z The results were sensational: Patients treated with chloroquine and hydroxychloroquine were up to five times as likely to have abnormal heart rhythms as other patients — and were at higher risk of dying. The Doctor Behind the Disputed Covid Data 2020-07-27T04:00:00Z But he also said it’s possible that widespread distribution of chloroquine may help protect residents of Amazonas from malaria. ‘The Biggest Monster’ Is Spreading. And It’s Not the Coronavirus. 2020-08-03T04:00:00Z Roughly 15% of these patients received hydroxychloroquine, the related drug chloroquine, or one or the other of these drugs paired with an antibiotic. Coronavirus research updates: Dogs’ and cats’ infection rates mirror those of people 2020-07-23T04:00:00Z He took over after his predecessor, a doctor and health care consultant, quit in protest over Bolsonaro’s support for the use of hydroxychloroquine and chloroquine, a related drug, as a treatment for COVID-19. Brazil’s Bolsonaro says he tested negative for coronavirus 2020-07-25T04:00:00Z The minister added he is being treated with a combination of drugs that includes chloroquine from which his body is showing “positive effects”. Brazil's minister of citizenship Onyx Lorenzoni tests positive for COVID-19 2020-07-20T04:00:00Z He took over after his predecessor, a doctor and health care consultant, quit in protest over Bolsonaro’s support for the use of hydroxychloroquine and chloroquine, a related drug. Brazil’s Bolsonaro gets new positive coronavirus test result 2020-07-15T04:00:00Z The president ordered the army to mass produce the anti-malarial drug, chloroquine, which hasn’t proven to be effective against the coronvavirus. As virus spreads, Bolsonaro ties with military under strain 2020-07-13T04:00:00Z The agency eventually had to backtrack, issuing an advisory on June 15 cautioning against the use of the drug or the related drug chloroquine for COVID-19. Column: Chloroquine again? Trump touts a new flawed study of useless coronavirus 'miracle drug' 2020-07-10T04:00:00Z Food and Drug administration in June, for example, revoked its emergency use authorization for hydroxychloroquine and chloroquine, saying it was no longer likely that the medications were effective at treating COVID-19 in these patients. Special Report: Bolsonaro bets 'miraculous cure' for COVID-19 can save Brazil - and his life 2020-07-08T04:00:00Z Brazil’s audit court on June 18 requested an investigation into alleged overbilling from local production of chloroquine, which it called unreasonable given the drug’s ineffectiveness and cited the FDA decision. Bolsonaro becomes ‘poster boy’ for unproven virus treatment 2020-07-08T04:00:00Z Federal prosecutors said they were investigating the visit for ignoring the wishes of Yanomami communities to remain isolated from society, violating rules of social distancing and distributing chloroquine to indigenous people. Indigenous leaders angry about coronavirus risk from Brazilian military visit 2020-07-03T04:00:00Z Now that several big trials have shown disappointing results, hope has faded that chloroquine or hydroxychloroquine might be miracle drugs against COVID-19. ‘It’s a nightmare.’ How Brazilian scientists became ensnared in chloroquine politics 2020-06-22T04:00:00Z This caused the agency to conclude that the risks of hydroxychloroquine and chloroquine are significant enough to override any potential benefits. America has a 63 million dose stockpile of hydroxychloroquine thanks to the Trump cult 2020-06-18T04:00:00Z “We’ve got hundreds of deaths a day. If there’s a possibility to lower that number with chloroquine, why not use it?” Special Report: Bolsonaro bets 'miraculous cure' for COVID-19 can save Brazil - and his life 2020-07-08T04:00:00Z Brazil’s interim health minister, an army general with no health experience before April, endorsed chloroquine as a COVID-19 treatment days after assuming the post in May. Bolsonaro becomes ‘poster boy’ for unproven virus treatment 2020-07-08T04:00:00Z Critics also cite the Food and Drug Administration’s emergency-use authorization of hydroxychloroquine and chloroquine as a covid-19 treatment in March as the president heavily promoted it — and despite lack of evidence. Trump pushing officials to speed up already-ambitious coronavirus vaccine timeline 2020-06-17T04:00:00Z Both chloroquine and hydroxychloroquine are known to be toxic at high doses, but most information on toxicity comes from studies on suicides and accidental poisonings, where the dose was often not precisely known. ‘It’s a nightmare.’ How Brazilian scientists became ensnared in chloroquine politics 2020-06-22T04:00:00Z By March 17, Bayer had offered the White House three million doses of chloroquine, which was discovered in the 1930s and is derived from the bark of the quinine tree. A Mad Scramble to Stock Millions of Malaria Pills, Likely for Nothing 2020-06-16T04:00:00Z Hydroxychloroquine and chloroquine are now flashpoints in Brazil’s polarized politics. Special Report: Bolsonaro bets 'miraculous cure' for COVID-19 can save Brazil - and his life 2020-07-08T04:00:00Z As Brazil’s death toll continued to climb - nearing 68,000 on Wednesday, the second-most in the world - the health ministry distributed millions of chloroquine pills across Brazil’s vast territory. Bolsonaro becomes ‘poster boy’ for unproven virus treatment 2020-07-08T04:00:00Z On Monday, the Food and Drug Administration withdrew its emergency use authorization for hydroxychloroquine and chloroquine, drugs touted by President Trump as treatments for Covid-19. Common Drug Reduces Coronavirus Deaths, Scientists Report 2020-06-16T04:00:00Z Since then, they have been accused of poisoning their patients with a high dose of chloroquine just to give the drug—praised by U.S. ‘It’s a nightmare.’ How Brazilian scientists became ensnared in chloroquine politics 2020-06-22T04:00:00Z Some versions of chloroquine are approved in the United States. A Mad Scramble to Stock Millions of Malaria Pills, Likely for Nothing 2020-06-16T04:00:00Z On March 21, two days after Trump’s comments, Bolsonaro announced he was ordering the Army Chemical and Pharmaceutical Laboratory to ramp up chloroquine production in Brazil for use as a COVID-19 treatment. Special Report: Bolsonaro bets 'miraculous cure' for COVID-19 can save Brazil - and his life 2020-07-08T04:00:00Z He announced he was directing the Brazilian army to ramp up output of chloroquine. Bolsonaro becomes ‘poster boy’ for unproven virus treatment 2020-07-08T04:00:00Z How many hundreds of thousands of people received hydroxychloroquine or chloroquine? ‘We’ve got to be able to move more quickly.’ The pandemic reality of COVID-19 clinical trials 2020-06-16T04:00:00Z Two patients from the high-dose group developed dangerous cardiac arrhythmias before death, a known side effect from chloroquine, and warning signs for future heart trouble were more common in the high-dose group. ‘It’s a nightmare.’ How Brazilian scientists became ensnared in chloroquine politics 2020-06-22T04:00:00Z In the end, none of the chloroquine was ever distributed from the stockpile; doctors preferred hydroxychloroquine, which is newer and has fewer side effects, they say. A Mad Scramble to Stock Millions of Malaria Pills, Likely for Nothing 2020-06-16T04:00:00Z Sixteen people taking higher chloroquine doses died, compared with six in the low-dosage group. Special Report: Bolsonaro bets 'miraculous cure' for COVID-19 can save Brazil - and his life 2020-07-08T04:00:00Z All say they worry Bolsonaro’s cheerleading will spur a new wave of desperate patients and relatives clamoring for chloroquine. Bolsonaro becomes ‘poster boy’ for unproven virus treatment 2020-07-08T04:00:00Z The agency said a laboratory study showed that chloroquine or hydroxychloroquine can reduce remdesivir’s antiviral activity. FDA pulls emergency approval for antimalarial drugs touted by Trump as covid-19 treatment 2020-06-15T04:00:00Z The participants in Lacerda’s trial were also given two to three other medications, including azithromycin, which shares chloroquine’s propensity to cause heart problems. ‘It’s a nightmare.’ How Brazilian scientists became ensnared in chloroquine politics 2020-06-22T04:00:00Z Hydroxychloroquine and chloroquine are frequently prescribed for lupus and rheumatoid arthritis. Coronavirus live news: global Covid-19 cases pass 8 million as Beijing closes sports halls 2020-06-15T04:00:00Z Hydroxychloroquine and chloroquine are frequently prescribed for lupus and rheumatoid arthritis. Hydroxychloroquine: US revokes emergency approval of malaria drug for Covid-19 2020-06-15T04:00:00Z Before she bounced back, some friends asked if she would authorize administration of either chloroquine or hydroxychloroquine were she unable to grant consent. Bolsonaro becomes ‘poster boy’ for unproven virus treatment 2020-07-08T04:00:00Z The donated chloroquine does not have FDA approval, but chloroquine made by other companies does. FDA pulls emergency approval for antimalarial drugs touted by Trump as covid-19 treatment 2020-06-15T04:00:00Z His comments about hydroxychloroquine became the subject of widespread speculation online and controversy within the scientific community about the potential benefits and harmful effects of the drug - along with the related drug, chloroquine. US withdraws use of malaria drug for coronavirus 2020-06-15T04:00:00Z The Food and Drug Administration is withdrawing emergency authorization for chloroquine and hydroxychloroquine as treatments for COVID-19, the agency announced today. FDA ends emergency authorization for hydroxychloroquine 2020-06-15T04:00:00Z The Food and Drug Administration said the drugs hydroxychloroquine and chloroquine are unlikely to be effective in treating the coronavirus. U.S. revokes emergency use of hydroxychloroquine, malaria drugs vs. coronavirus 2020-06-15T04:00:00Z The agency said Monday that the drugs hydroxychloroquine and chloroquine are unlikely to be effective in treating the coronavirus. US revokes emergency use of malaria drugs vs. coronavirus 2020-06-15T04:00:00Z “Today chloroquine became a political panacea, which is harmful for science,” she said in an interview. Brazil President Embraces Unproven ‘Cure’ as Pandemic Surges 2020-06-13T04:00:00Z Hydroxychloroquine and its sister drug chloroquine have been used against malaria and other diseases for decades. Three big studies dim hopes that hydroxychloroquine can treat or prevent COVID-19 2020-06-09T04:00:00Z The study tied the malaria drugs hydroxychloroquine and chloroquine to a higher risk of death in hospitalized patients with the virus. Dr. Marc Siegel on faulty hydroxychloroquine data: 'This is a political hit job' 2020-06-06T04:00:00Z It had published a study involving nearly 15,000 patients, from hundreds of hospitals, given hydroxycholoroquine or the similar drug chloroquine. Malaria drug 'does not save lives' from coronavirus 2020-06-05T04:00:00Z The retractions may breathe new life into the antimalarial drugs hydroxychloroquine and chloroquine, relentlessly promoted by Mr. Trump as a remedy for Covid-19 despite a lack of evidence. Two Huge Covid-19 Studies Are Retracted After Scientists Sound Alarms 2020-06-04T04:00:00Z Nearly 15,000 were given hydroxychloroquine - or a related form, chloroquine - either alone or with an antibiotic. Influential study on coronavirus drug withdrawn 2020-06-04T04:00:00Z A meta-analysis of 24 such studies published in the Annals of Internal Medicine concluded there was “insufficient and often conflicting evidence on the benefits and harms of using hydroxychloroquine or chloroquine to treat COVID-19.” Three big studies dim hopes that hydroxychloroquine can treat or prevent COVID-19 2020-06-09T04:00:00Z A recent large study on the controversial drugs chloroquine and hydroxychloroquine was just retracted by The Lancet, the scientific journal that published it. Hydroxychloroquine study retraction shows the problems of speedy science 2020-06-04T04:00:00Z Soon after, a US man died after he drank chloroquine found in fish tank cleaner because he was scared of getting sick. Unreliable data: how doubt snowballed over Covid-19 drug research that swept the world 2020-06-04T04:00:00Z The paper about chloroquine and hydroxychloroquine appeared in late May in The Lancet. Two Huge Covid-19 Studies Are Retracted After Scientists Sound Alarms 2020-06-04T04:00:00Z Following Mr Trump's comments, there was a sharp increase reported in prescriptions in the US for both hydroxychloroquine and the related drug, chloroquine. Influential study on coronavirus drug withdrawn 2020-06-04T04:00:00Z Hydroxychloroquine and a similar drug, chloroquine, have been the subject of much debate since Trump started promoting them in March. Malaria drug fails to prevent COVID-19 in a rigorous study 2020-06-03T04:00:00Z Meanwhile, the questions swirling around the Lancet paper have left leaders of the halted chloroquine trials weighing whether to restart. A mysterious company’s coronavirus papers in top medical journals may be unraveling 2020-06-02T04:00:00Z Fauci tried tactfully to dampen the president’s hype of hydroxychloroquine and the antiviral drug chloroquine. Fauci says his contact with Trump has 'dramatically decreased' 2020-06-01T04:00:00Z All told there were almost a half-million more prescriptions for hydroxychloroquine and chloroquine filled between mid-February and late April compared with the same period in 2019. Coronavirus Continues to Disrupt Prescription Drug Supplies 2020-05-28T04:00:00Z In total, the researchers found that 483,425 excess prescriptions of hydroxychloroquine and chloroquine were filled between Feb. 16 and April 25. Hydroxychloroquine prescriptions rose nearly 2,000 percent the week Trump 'supported' it: study 2020-05-29T04:00:00Z Cypriot authorities procured enough chloroquine to treat as many as 240,000 people - roughly a quarter of the island nation’s population - if they became infected. Cyprus curtails use of chloroquine over side-effect concerns 2020-05-28T04:00:00Z According to the paper, the analysis included nearly 15,000 patients prescribed chloroquine or hydroxychloroquine, alone or in combination with a class of antibiotics that has been suggested to boost its effects. A mysterious company’s coronavirus papers in top medical journals may be unraveling 2020-06-02T04:00:00Z Cypriot authorities procured enough chloroquine to treat as many as 240,000 people — roughly a quarter of the island nation’s population — if they became infected. Cyprus curtails use of chloroquine over side-effect concerns 2020-05-28T04:00:00Z After peaking in mid-March, prescriptions for hydroxychloroquine and chloroquine declined substantially but mostly remained elevated above their normal levels throughout April. Coronavirus Continues to Disrupt Prescription Drug Supplies 2020-05-28T04:00:00Z "We are also aware of increased use of these medicines through outpatient prescriptions. Therefore, we would like to remind health care professionals and patients of the known risks associated with both hydroxychloroquine and chloroquine." Hydroxychloroquine prescriptions rose nearly 2,000 percent the week Trump 'supported' it: study 2020-05-29T04:00:00Z A man in Arizona died, and his wife was hospitalized, after they took chloroquine phosphate – used to clean fish tanks. As 100,000 die, the virus lays bare America's brutal fault lines – race, gender, poverty and broken politics 2020-05-28T04:00:00Z On Twitter in early March, technology entrepreneurs and investors shared a document prematurely extolling the benefits of chloroquine, an old malaria drug, as an antiviral against COVID‑19. The epic battle against coronavirus misinformation and conspiracy theories 2020-05-26T04:00:00Z Researchers also reviewed patients who received the related drug chloroquine, as well as those treated with a combination of one of those drugs and an antibiotic such as azithromycin or clarithromycin. Google seems to be squelching searches for Trump's "miracle" drug after damning new study 2020-05-27T04:00:00Z His successor, Nelson Teich, spent less than a month in charge and resigned after refusing to promote the use of chloroquine to treat patients, as Bolsonaro desired. Brazil envoy to U.S. praises warning, aid despite travel ban 2020-05-26T04:00:00Z Roughly 15% of these patients received hydroxychloroquine, the related drug chloroquine, or one of those two paired with an antibiotic. Coronavirus research updates: Trump’s favoured drug shows no benefit — but another drug does 2020-05-24T04:00:00Z He also urged caution about the malaria drug chloroquine. Special Report: Bolsonaro brought in his generals to fight coronavirus. Brazil is losing the battle 2020-05-26T04:00:00Z There were small spikes in Google searches for hydroxychloroquine, chloroquine and their key ingredient, quinine, in mid-March — with the largest surge on the day of Trump’s remarks, Donovan found using Google Trends. The epic battle against coronavirus misinformation and conspiracy theories 2020-05-26T04:00:00Z Bolsonaro ordered the Army’s Chemical and Pharmaceutical Laboratory to boost its chloroquine production despite a lack of clinical proof that it is effective. Death and denial in Brazil’s Amazon capital 2020-05-26T04:00:00Z Hydroxychloroquine and chloroquine are approved to treat malaria and the autoimmune diseases lupus and rheumatoid arthritis. Malaria Drug Taken by Trump Is Tied to Increased Risk of Heart Problems and Death in New Study 2020-05-22T04:00:00Z People treated with hydroxychloroquine, or the closely related drug chloroquine, were also more likely to develop a type of irregular heart rhythm, or arrhythmia, that can lead to sudden cardiac death, it concluded. Antimalarial drug touted by President Trump is linked to increased risk of death in coronavirus patients, study says 2020-05-22T04:00:00Z In laboratory experiments, hydroxychloroquine and chloroquine both inhibited the novel coronavirus. Beyond politics, gold-standard COVID-19 trials test malaria drug taken by Trump 2020-05-22T04:00:00Z Overall, 14,888 patients received hydroxychloroquine or chloroquine, with or without an antibiotic, and 81,144 did not receive those drugs. Coronavirus vaccine safe in early trial; hydroxychloroquine may increase death risk 2020-05-22T04:00:00Z But he resigned days later after disagreeing with the president’s demand that the ministry recommend chloroquine be prescribed to patients with mild coronavirus symptoms. Death and denial in Brazil’s Amazon capital 2020-05-26T04:00:00Z The US president then claimed hydroxychloroquine – less toxic than the original chloroquine – was a cure, and later said he was taking it himself against coronavirus. Hydroxychloroquine: Trump's Covid-19 'cure' increases deaths, global study finds 2020-05-22T04:00:00Z There have been at least 13 studies in recent months on hydroxychloroquine or chloroquine as a treatment for covid-19 patients. Antimalarial drug touted by President Trump is linked to increased risk of death in coronavirus patients, study says 2020-05-22T04:00:00Z This research probably won’t settle the political debate over hydroxychloroquine and chloroquine. New study finds chloroquine doesn’t help COVID-19 patients — and it might even hurt 2020-05-22T04:00:00Z The president of the National Academy of Medicine and I signed a statement about the use of chloroquine and hydroxychloroquine, stating what science knows about these drugs and criticizing the government’s position. ‘Medications should be prescribed by doctors, not the president.’ 2020-05-21T04:00:00Z Facebook also blocked one of his posts in March that showed him praising the healing powers of chloroquine to supporters. Death and denial in Brazil’s Amazon capital 2020-05-26T04:00:00Z “We are also aware of increased use of these medicines through outpatient prescriptions. Therefore, we would like to remind health care professionals and patients of the known risks associated with both hydroxychloroquine and chloroquine.” Lupus patient on hydroxychloroquine contracts coronavirus, report says 2020-05-21T04:00:00Z Those given chloroquine had a 37 percent increased risk of death and a 256 percent increased risk of serious heart arrhythmias. Antimalarial drug touted by President Trump is linked to increased risk of death in coronavirus patients, study says 2020-05-22T04:00:00Z The interim health minister, Eduardo Pazuello, an army general, authorised the use after two doctors left the ministry’s top job under pressure to promote early use of chloroquine and hydroxychloroquine. Global report: don't count on vaccine, US scientist warns, as cases near 5 million 2020-05-21T04:00:00Z At sites in Asia, participants will be given chloroquine or a placebo. Malaria pill trialled to prevent coronavirus 2020-05-20T04:00:00Z Interim Health Minister Eduardo Pazuello, an active duty army general, authorized the modified protocol after two trained doctors left the ministry’s top job under pressure to promote early use of chloroquine and hydroxychloroquine. Brazil coronavirus outbreak worsens, cases could soon be second highest in world 2020-05-20T04:00:00Z On Tuesday he again defended use of the unproven drug chloroquine as a remedy, despite alerts it may be unsafe. Brazil daily virus deaths hit 1,000 for first time 2020-05-20T04:00:00Z For those taking chloroquine and an antibiotic, there was a 37 percent increased risk of death and a 301 percent increased risk of serious heart arrhythmias. Antimalarial drug touted by President Trump is linked to increased risk of death in coronavirus patients, study says 2020-05-22T04:00:00Z On April 24, the F.D.A. issued a warning about hydroxychloroquine and chloroquine, cautioning against their use “outside of the hospital setting or a clinical trial due to risk of heart rhythm problems.” Amid Hydroxychloroquine Uproar, Real Studies of Drug Are Suffering 2020-05-19T04:00:00Z One of the study's leaders, Prof Nicholas White at the University of Oxford said: "We really do not know if chloroquine or hydroxychloroquine are beneficial or harmful against Covid-19." Malaria pill trialled to prevent coronavirus 2020-05-20T04:00:00Z It is sometimes referred to by its brand name, Plaquenil, and is closely related to chloroquine, which is also used to treat malaria. What to Know About the Malaria Drug Trump Says He Is Using 2020-05-18T04:00:00Z So far, there is insufficient evidence from medical trials that chloroquine - and a related drug hydroxychloroquine - is effective to either prevent or treat the virus. Brazil daily virus deaths hit 1,000 for first time 2020-05-20T04:00:00Z Following Mr Trump's comments in late March, there was a sharp increase reported in prescriptions in the US for both chloroquine and hydroxychloroquine. What's the malaria pill Trump's taking? 2020-05-19T04:00:00Z Bolsonaro added that his mother is 93 years old, and he keeps a box of chloroquine on hand should she need it. Brazil suffers record coronavirus deaths, Trump mulls travel ban 2020-05-19T04:00:00Z After Trump hyped the drug in March, an Arizona man died from ingesting a form of chloroquine used to clean fish tanks. Trump is taking hydroxychloroquine, White House confirms 2020-05-19T04:00:00Z Bolsonaro said his own mother is 93 and he keeps a box of chloroquine in case she needs it. Coronavirus live news: Brazil sees record daily deaths as World Bank warns 60m to fall into extreme poverty 2020-05-19T04:00:00Z A study in Virology Journal in 2005 found that chloroquine inhibited the closely related Sars virus in primate cells in lab conditions. Hydroxychloroquine, Trump and Covid-19: what you need to know 2020-05-19T04:00:00Z In the US, various trials are under way for a combination of drugs including chloroquine, hydroxychloroquine and an antibiotic called azithromycin, for treating Covid-19 patients. What's the malaria pill Trump's taking? 2020-05-19T04:00:00Z The April 24 safety alert warned that the agency had received reports that hydroxychloroquine and chloroquine, a related drug, could have serious side effects. Trump says he is taking hydroxychloroquine to protect against coronavirus, dismissing safety concerns 2020-05-18T04:00:00Z Along with Fox News, Musk was an early proponent of the antimalarial drug chloroquine as a treatment for COVID-19, an idea that has been discredited by clinical trials. Elon Musk is playing Twitter footsie with the fringe right 2020-05-18T04:00:00Z He also said that he saw Trump say he was taking chloroquine. Coronavirus live news: Brazil sees record daily deaths as World Bank warns 60m to fall into extreme poverty 2020-05-19T04:00:00Z Nelson Teich stepped down as health minister Friday after Bolosnaro pushed to lift lockdown measures and the widespread use of the drug chloroquine to treat the virus without further testing. Brazil's Bolsonaro flouts social distancing, poses for pics with kids as São Paulo health system reaches near collapse 2020-05-18T04:00:00Z A number of countries restricted sales so that chloroquine was only available on prescription or in hospitals. What's the malaria pill Trump's taking? 2020-05-19T04:00:00Z Still, because chloroquine and hydroxychloroquine are available for use in other conditions, doctors were able to provide Covid-19 patients with “off-label” treatment if they believed it would provide a benefit. He Was a Science Star. Then He Promoted a Questionable Cure for Covid-19. 2020-05-12T04:00:00Z A man in Phoenix died after ingesting fish tank cleaner, which contained chloroquine, a chemical that Mr. Trump touted as a possible coronavirus treatment. Opinion | Fighting the coronavirus means fighting misinformation, too 2020-05-15T04:00:00Z The FDA said in a statement Friday that it is continuing to evaluate its emergency use authorization for chloroquine and hydroxychloroquine, as it does with all such authorizations for drugs to ensure their continued safety. Drug promoted by Trump as coronavirus ‘game changer’ increasingly linked to deaths 2020-05-15T04:00:00Z He disagreed with the president's desire to widely use chloroquine as a treatment. Brazil loses second health minister in a month 2020-05-15T04:00:00Z In Nigeria, households still regularly use tablets containing chloroquine for treating malaria, even though it was banned in 2005 for first-line use because of its declining effectiveness. What's the malaria pill Trump's taking? 2020-05-19T04:00:00Z An early report on chloroquine showed good results in vitro. He Was a Science Star. Then He Promoted a Questionable Cure for Covid-19. 2020-05-12T04:00:00Z Dr. Bright said he finally appealed to the public after he tried to put limits on the distribution of chloroquine and hydroxychloroquine. ‘Lives Were Lost’ as Warnings Went Unheeded, Whistle-Blower Tells House 2020-05-14T04:00:00Z Doctors in Brazil stopped a trial of chloroquine, closely related to hydroxychloroquine, after 11 patients died. Drug promoted by Trump as coronavirus ‘game changer’ increasingly linked to deaths 2020-05-15T04:00:00Z In a whistleblower complaint, Bright has claimed he was removed after resisting pressure by the administration to make “potentially harmful drugs widely available”, including chloroquine and hydroxychloroquine. Ousted whistleblower warns US facing ‘darkest winter in modern history’ 2020-05-14T04:00:00Z But even for pharmaceuticals that are already produced in bulk — such as hydroxychloroquine and chloroquine — scaling up presents a significant problem, says David Simchi-Levi, an operations researcher at the Massachusetts Institute of Technology in Cambridge. How to make enough coronavirus drugs in a hurry 2020-05-13T04:00:00Z Hydroxychloroquine, along with its more toxic analog chloroquine, was for several decades the most commonly prescribed antimalarial drug in the world. He Was a Science Star. Then He Promoted a Questionable Cure for Covid-19. 2020-05-12T04:00:00Z He said he assented to the F.D.A.’s “emergency use authorization” for chloroquine, which is unapproved in the United States, because the F.D.A. limited its use to hospital patients under close medical supervision. ‘Lives Were Lost’ as Warnings Went Unheeded, Whistle-Blower Tells House 2020-05-14T04:00:00Z Two other medicines — hydroxychloroquine and chloroquine — provide another case study in the pitfalls of small and uncontrolled trials. Coronavirus drugs trials must get bigger and more collaborative 2020-05-12T04:00:00Z In March, the FDA approved emergency use authorization to try several drugs, including hydroxychloroquine and chloroquine, in an effort to combat COVID-19, despite a lack of clear evidence of their effectiveness. Hydroxychloroquine had no benefits for 'seriously ill' coronavirus patients, study says 2020-05-12T04:00:00Z The document describes one such clash in mid-March after Bayer offered to donate 3 million chloroquine pills to the national stockpile, which is run by HHS’ Office of the Assistant Secretary for Preparedness and Response. Ousted vaccine official alleges he was demoted for prioritizing ‘science and safety’ 2020-05-05T04:00:00Z Raoult reviewed that evidence in a 2007 paper, concluding that chloroquine and hydroxychloroquine might be “an interesting weapon to face present and future infectious diseases worldwide.” He Was a Science Star. Then He Promoted a Questionable Cure for Covid-19. 2020-05-12T04:00:00Z A spokeswoman for HHS has said it was Bright who had requested an emergency use authorization for chloroquine and hydroxychloroquine. Ousted HHS official Rick Bright files whistleblower complaint 2020-05-05T04:00:00Z In an alert, regulators flagged reports of sometimes fatal heart side effects among coronavirus patients taking hydroxychloroquine or the related drug chloroquine. Scientist says he was fired after concerns over malaria drug 2020-05-05T04:00:00Z The anti-malaria drugs chloroquine and hydroxychloroquine act on the Sigma receptor. Old Drugs May Find a New Purpose: Fighting the Coronavirus 2020-04-30T04:00:00Z The authorization that was ultimately issued, which applies to chloroquine and hydroxychloroquine from the national stockpile, is limited to hospitalized patients with covid-19 who cannot participate in a clinical trial. Ousted vaccine official alleges he was demoted for prioritizing ‘science and safety’ 2020-05-05T04:00:00Z Given the similarities between intracellular bacteria and viruses, Raoult suspected that chloroquine and hydroxychloroquine might have antiviral effects. He Was a Science Star. Then He Promoted a Questionable Cure for Covid-19. 2020-05-12T04:00:00Z For instance, he promoted a dubious paper on chloroquine, which was immediately ripped apart — the authors were blockchain hucksters, not medical researchers. Was Elon’s Tesla Twitter meltdown illegal? An investigation 2020-05-01T04:00:00Z Wanda, 61, told NBC News that she and her husband ingested the fish tank cleaner after hearing President Trump talk about the possible benefits of chloroquine to fend off the virus. Police investigating case of Arizona man who died after ingesting fish tank cleaner 2020-04-29T04:00:00Z Dr. Chanda expressed skepticism about the chloroquine drugs, noting their failure against other viruses. Old Drugs May Find a New Purpose: Fighting the Coronavirus 2020-04-30T04:00:00Z Bright’s statement, nevertheless, has made him a hero among some in the scientific community, who have expressed concern for weeks about the president’s unproven claims about hydroxychloroquine and chloroquine. Ousted vaccine official alleges he was demoted for prioritizing ‘science and safety’ 2020-05-05T04:00:00Z The Chinese reports, however, appeared to confirm Raoult’s longstanding hopes for chloroquine. He Was a Science Star. Then He Promoted a Questionable Cure for Covid-19. 2020-05-12T04:00:00Z The FDA flagged reports of serious side effects and death among patients taking hydroxychloroquine and the related drug chloroquine. Excerpts from recent South Dakota editorials 2020-04-29T04:00:00Z On March 14th, he said the “danger of panic still far exceeds danger of corona,” as part of a larger thread promoting chloroquine as an effective treatment. Elon Musk is dangerously wrong about the novel coronavirus 2020-04-29T04:00:00Z They found that chloroquine and hydroxychloroquine bind not just to Sigma receptors, but to a heart protein called hERG, which helps control heartbeats. Old Drugs May Find a New Purpose: Fighting the Coronavirus 2020-04-30T04:00:00Z Despite the lack of evidence, the presidential endorsement drove up online searches for buying hydroxychloroquine, and its chemical cousin chloroquine, by 1,389% and 442% respectively. Online demand for hydroxychloroquine surged 1,000% after Trump backed it, study finds 2020-04-29T04:00:00Z To ward off malaria, he was given chloroquine. He Was a Science Star. Then He Promoted a Questionable Cure for Covid-19. 2020-05-12T04:00:00Z “Now there’s some evidence the chloroquine may not be as effective, but I was being proactive to try and protect Oklahomans,” Stitt said Tuesday when asked about the purchase. Oklahoma, Utah face scrutiny over malaria drug purchases 2020-04-28T04:00:00Z He promoted a widely discredited paper on the benefits of chloroquine, which was debunked so quickly that both Twitter and Google Docs refused to host it. Elon Musk is dangerously wrong about the novel coronavirus 2020-04-29T04:00:00Z In a press conference last month, President Trump and FDA Commissioner Dr. Stephen Hahn described several approaches under testing, such as hydroxychloroquine and chloroquine, drugs long used to treat malaria, and remdesivir. COVID-19 survivors answer your questions: How long to feel normal again? 2020-04-28T04:00:00Z The authors looked at the prevalence of internet searches using the terms “buy”, “order”, “Amazon”, “eBay” or “Walmart” in combination with “hydroxychloroquine” or “chloroquine”. Online demand for hydroxychloroquine surged 1,000% after Trump backed it, study finds 2020-04-29T04:00:00Z "The FDA is aware of reports of serious heart rhythm problems in patients with COVID-19 treated with hydroxychloroquine or chloroquine, often in combination with azithromycin," the FDA wrote on its website. Former FDA commissioner on use of hydroxychloroquine and Georgia reopening 2020-04-26T04:00:00Z She concluded from her research that chloroquine might help, and she didn’t see any harm in writing a short prescription. Prescriptions Surged as Trump Praised Drugs in Coronavirus Fight 2020-04-25T04:00:00Z It is the nightmare of watching someone listen to the president, self-administer chloroquine and die. Opinion | America, please don’t put bleach inside yourself like the president says 2020-04-24T04:00:00Z The FDA’s safety message Friday came after weeks of warnings from experts about possible complications from hydroxychloroquine and chloroquine. FDA warns about hydroxychloroquine dangers, citing serious heart issues, including death 2020-04-24T04:00:00Z Since the endorsements by Trump and Musk, the US Food and Drug Administration has issued a warning about potentially life-threatening cardiac side-effects associated with chloroquine and hydroxychloroquine. Online demand for hydroxychloroquine surged 1,000% after Trump backed it, study finds 2020-04-29T04:00:00Z In an alert, regulators flagged reports of serious side effects and death among patient s taking hydroxychloroquine and the related drug chloroquine. South Dakota continues malaria drug trial despite FDA alert 2020-04-24T04:00:00Z The interest in taking chloroquine and hydroxychloroquine as a possible treatment did not originate with Mr. Trump. Prescriptions Surged as Trump Praised Drugs in Coronavirus Fight 2020-04-25T04:00:00Z The drugs hydroxychloroquine and chloroquine should not be used outside of a hospital or clinical setting, the agency said, especially when used alongside the antibiotic azithromycin, also known as a Z-Pak. Hydroxychloroquine use should be avoided outside of hospitals, FDA warns 2020-04-24T04:00:00Z Bright’s statement, nevertheless, has made him a hero among some in the scientific community, who have expressed concern for weeks about the president’s unfounded claims about hydroxychloroquine and chloroquine without evidence. FDA warns about hydroxychloroquine dangers, citing serious heart issues, including death 2020-04-24T04:00:00Z In an alert Friday, regulators warned of reports of serious side effects and death among patients taking hydroxychloroquine and the related drug chloroquine. FDA warns of risks with Trump-promoted malaria drug 2020-04-24T04:00:00Z Earlier this year, an Arizona man died and his wife was hospitalized after they ingested a fish tank cleaner containing chloroquine, a form of an anti-malarial drug touted by Trump. Trump admin. warns Americans not to inject disinfectant after president floats new coronavirus cure 2020-04-24T04:00:00Z A small trial in Brazil of chloroquine was halted after coronavirus patients taking higher doses developed irregular heart rates that increased their risk of a potentially fatal heart arrhythmia. Prescriptions Surged as Trump Praised Drugs in Coronavirus Fight 2020-04-25T04:00:00Z Taken together, these trials suggested that chloroquine treatment might shorten the duration of the disease2. Chloroquine hype is derailing the search for coronavirus treatments 2020-04-23T04:00:00Z "Specifically, and contrary to misguided directives, I limited the broad use of chloroquine and hydroxychloroquine, promoted by the administration as a panacea, but which clearly lack scientific merit." Doctor says he was fired for resisting Trump's promotion of untested COVID-19 treatments 2020-04-24T04:00:00Z Experts had warned that there were no proven indications the drug, chloroquine, was effective and said that it could be dangerous, as some studies have shown it to be. U.S., Australia call for global investigation of pandemic response; Pompeo says WHO funding freeze could be permanent 2020-04-23T04:00:00Z "Specifically, and contrary to misguided directives, I limited the broad use of chloroquine and hydroxychloroquine, promoted by the administration as a panacea, but which clearly lack scientific merit," he continued. Doctor claims he was removed for questioning unproven drug treatment for coronavirus hyped by Trump 2020-04-23T04:00:00Z The EMA reminded doctors and patients to report any suspected side effects from hydroxychloroquine and chloroquine to national authorities. EU: Malaria drugs used for virus could cause side effects 2020-04-23T04:00:00Z Trump claimed that he considered taking chloroquine as a precautionary measure. Chloroquine hype is derailing the search for coronavirus treatments 2020-04-23T04:00:00Z Contrary to misguided directives, I limited the broad use of chloroquine and hydroxychloroquine, promoted by the administration as a panacea, but which clearly lack scientific merit. First thing: The Trump administration's coronavirus whistleblower 2020-04-23T04:00:00Z “To date, almost 40 studies have reported apparent usefulness of hydroxychloroquine or chloroquine in shortening length of hospital stay, improving symptoms, and resolving lung lesions as seen on X-rays.” Health Dept. Official Says Doubts on Hydroxychloroquine Led to His Ouster 2020-04-22T04:00:00Z The scientists tested five drugs in vitro – meaning on cells infected with the virus in a laboratory rather than in humans – and found promising results for two: remdesivir and chloroquine. Hydroxychloroquine and coronavirus: a guide to the scientific studies so far 2020-04-23T04:00:00Z The European Medicines Agency said in a statement that chloroquine and hydroxychloroquine - two medicines embraced by U.S. EU: Malaria drugs used for virus could cause side effects 2020-04-23T04:00:00Z Meanwhile, there were reports of illness and deaths linked to chloroquine overdoses in the United States and Nigeria. Chloroquine hype is derailing the search for coronavirus treatments 2020-04-23T04:00:00Z "Specifically, and contrary to misguided directives, I limited the broad use of chloroquine and hydroxychloroquine, promoted by the administration as a panacea, but which clearly lack scientific merit," Bright added. HHS doctor says he was removed from post after disagreeing with WH over coronavirus response 2020-04-22T04:00:00Z In the absence of any known effective treatments, doctors on the frontlines said they began using hydroxychloroquine and chloroquine on deteriorating patients based on a few small studies suggesting a possible benefit. U.S. official says he was ousted for urging caution on Trump-touted coronavirus drug 2020-04-22T04:00:00Z The panel said that there was insufficient data to “recommend either for or against” hydroxychloroquine or chloroquine. Hydroxychloroquine and coronavirus: a guide to the scientific studies so far 2020-04-23T04:00:00Z “Contrary to misguided directives,” Dr. Bright said, he “limited the broad use of chloroquine and hydroxychloroquine, promoted by the Administration as a panacea, but which clearly lack scientific merit.” Vaccine agency director claims retaliation over hydroxychloroquine, vows whistleblower complaint 2020-04-22T04:00:00Z “Specifically, and contrary to misguided directives, I limited the broad use of chloroquine and hydroxychloroquine, promoted by the administration as a panacea, but which clearly lack scientific merit,” Bright said. Top vaccine expert claims he was fired for resisting Trump on hydroxychloroquine 2020-04-22T04:00:00Z "There are insufficient clinical data to recommend either for or against using chloroquine or hydroxychloroquine for the treatment of COVID-19," the panel said. Trump and Fox News stop hyping hydroxychloroquine as NIH warns against using it to treat COVID-19 2020-04-22T04:00:00Z Furthermore, they found that if autophagy was inhibited in mice, by drugs such as chloroquine or through genetic engineering, this restored the surface expression of MHC class I molecules, thereby enhancing antigen presentation. Pancreatic cancer hidden in plain sight 2020-04-21T04:00:00Z Researchers in Brazil ended a portion of a clinical trial testing high doses of chloroquine in covid-19 patients after they developed heart problems and suffered higher mortality. Anti-malarial drug Trump touted is linked to higher rates of death in VA coronavirus patients, study says 2020-04-21T04:00:00Z For now, the agency isn’t giving advice on the malaria drug chloroquine or several drugs of high interest, many of which are undergoing clinical trials. Here's what scientists still wish they knew about the coronavirus 2020-04-22T04:00:00Z National Institutes of Health all recommend that patients only receive chloroquine or hydroxychloroquine in the context of a clinical trial until there is more evidence that the drugs are effective. Antimalarials widely used against COVID-19 heighten risk of cardiac arrest. How can doctors minimize the danger? 2020-04-21T04:00:00Z "If chloroquine or hydroxychloroquine is used, clinicians should monitor the patient for adverse effects." Trump and Fox News stop hyping hydroxychloroquine as NIH warns against using it to treat COVID-19 2020-04-22T04:00:00Z The Food and Drug Administration recently announced an emergency use authorization to try several drugs, including hydroxychloroquine and chloroquine, despite a lack of clear evidence of their effectiveness. Controversial coronavirus treatment hydroxychloroquine should be used, 25 percent of doctors say: survey 2020-04-21T04:00:00Z Others were harsher, especially about Mr. Trump’s idea of combining a chloroquine with azithromycin. The Coronavirus in America: The Year Ahead 2020-04-18T04:00:00Z The Federal Aviation Administration on Tuesday barred pilots from taking hydroxychloroquine and closely related chloroquine within 48 hours of flying. AP FACT CHECK: Trump is not a king 2020-04-18T04:00:00Z NIH is stepping in partly because of concerns that some potential treatments, such as hydroxychloroquine/chloroquine, are being touted by some researchers as effective based on poorly designed trials. To tame testing chaos, NIH and firms join forces to streamline coronavirus vaccine and drug efforts 2020-04-17T04:00:00Z In the Brazil study, two of the 37 patients who were getting high doses of chloroquine developed ventricular tachycardia, a dangerous heart arrhythmia that led to their deaths. Malaria drugs fail to help coronavirus patients in controlled studies 2020-04-17T04:00:00Z THE FACTS: Michigan’s Department of Licensing and Regulatory Affairs released a memo in March asking for physicians and pharmacists not to stockpile hydroxychloroquine or chloroquine. NOT REAL NEWS: More falsehoods around the novel coronavirus 2020-04-17T04:00:00Z She was given chloroquine as a treatment, not to be confused with hydroxychloroquine, the unproven drug touted by President Trump as a potential coronavirus treatment. Rita Wilson says coronavirus fight was 'easier' since husband Tom Hanks had it, too 2020-04-17T04:00:00Z Trump first endorsed chloroquine drugs to treat COVID-19 from the White House podium on March 19, citing “very, very encouraging early results” and downplaying any risks. Exclusive: Bayer's chloroquine donation to U.S. raises concern about FDA standards in pandemic 2020-04-16T04:00:00Z On March 28 the FDA issued an emergency authorization for administering chloroquine or hydroxychloroquine to COVID-19 patients—but many experts say the widespread usage of these drugs is premature. Here’s What We Know about the Most Touted Drugs Tested for COVID-19 2020-04-16T04:00:00Z The death toll among patients who were randomly assigned to receive high-dose chloroquine did not rise above that in a comparison group of patients who did not get the drug. Malaria drugs fail to help coronavirus patients in controlled studies 2020-04-17T04:00:00Z Wilson and Hanks were admitted to Gold Coast University hospital in Queensland for treatment, where Wilson said she was given chloroquine after she developed a fever of 38.9C. Rita Wilson tells of 'extreme side effects' of experimental Covid-19 drug chloroquine 2020-04-15T04:00:00Z Wilson previously talked about taking chloroquine, a drug typically used to treat malaria patients, on an episode of “The Talk” with Gayle King. Rita Wilson says coronavirus fight was 'easier' since husband Tom Hanks had it, too 2020-04-17T04:00:00Z In emails two days later, federal health officials greeted the Bayer donation of chloroquine phosphate, or Resochin, with eagerness. Exclusive: Bayer's chloroquine donation to U.S. raises concern about FDA standards in pandemic 2020-04-16T04:00:00Z Some scientists say the preclinical evidence is strong enough to support chloroquine’s use, however. Here’s What We Know about the Most Touted Drugs Tested for COVID-19 2020-04-16T04:00:00Z She said her fever subsided after taking chloroquine, but she's not sure if it's the reason it went away. Rita Wilson opens up about coronavirus symptoms, warns about 'extreme' chloroquine side effects 2020-04-14T04:00:00Z In March, a man in Arizona died after taking chloroquine phosphate – a chemical used to clean fish tanks – after Trump’s advice. Rita Wilson tells of 'extreme side effects' of experimental Covid-19 drug chloroquine 2020-04-15T04:00:00Z A recent study in Brazil of chloroquine, which is similar to hydroxychloroquine, was halted early because a number of test subjects developed dangerous heart problems. Anti-malarial drug touted by Trump was subject of CIA warning to employees 2020-04-13T04:00:00Z Resochin is part of a class of medications containing one of two active ingredients - chloroquine or hydroxychloroquine - that the Trump administration has praised as a potentially lifesaving treatment. Exclusive: Bayer's chloroquine donation to U.S. raises concern about FDA standards in pandemic 2020-04-16T04:00:00Z Back in March, the Food and Drug Administration granted an emergency use authorization allowing doctors to prescribe chloroquine and hydroxychloroquine for COVID-19 patients. Column: Experts lose enthusiasm for chloroquine coronavirus treatment promoted by Trump 2020-04-13T04:00:00Z Now, the singer and actress has opened up in greater detail about the couple's symptoms and their experience with the controversial drug chloroquine. Rita Wilson opens up about coronavirus symptoms, warns about 'extreme' chloroquine side effects 2020-04-14T04:00:00Z A spokeswoman for Gold Coast University hospital would not confirm whether Hanks and Wilson were given chloroquine, but said that “selected patients” did receive the drug. Rita Wilson tells of 'extreme side effects' of experimental Covid-19 drug chloroquine 2020-04-15T04:00:00Z At the time Hall and Arad were speaking, practitioners were struggling to gauge the utility of treating coronavirus patients with chloroquine or a derivative called hydroxychloroquine, which is used to treat autoimmune diseases like lupus. How New Jersey’s First Coronavirus Patient Survived 2020-04-05T04:00:00Z But the effectiveness of chloroquine drugs against coronavirus has not been proven. Exclusive: Bayer's chloroquine donation to U.S. raises concern about FDA standards in pandemic 2020-04-16T04:00:00Z The latter is the case with chloroquine and hydroxychloroquine. Column: Experts lose enthusiasm for chloroquine coronavirus treatment promoted by Trump 2020-04-13T04:00:00Z The actress revealed she was given chloroquine, a drug that has been used to prevent and treat malaria that is being studied as a possible COVID-19 treatment. Rita Wilson opens up about coronavirus symptoms, warns about 'extreme' chloroquine side effects 2020-04-14T04:00:00Z The FDA has issued an emergency use authorization for hydroxychloroquine and chloroquine to treat covid-19, but several former FDA leaders and other scientists have condemned that decision. Perspective | How to conduct coronavirus research at pandemic speed 2020-04-10T04:00:00Z Speaking about hydroxychloroquine and the related drug chloroquine, Kalil said, "They are toxic to the heart, toxic to the liver, toxic to the bone marrow — and those are three essential organs to fight infections." Is hydroxychloroquine making COVID-19 clinical trials harder? 2020-04-11T04:00:00Z In 2016, the FDA issued a warning letter to Ipca regarding three of its plants in India that make chloroquine ingredients and finished pills for companies other than Bayer. Exclusive: Bayer's chloroquine donation to U.S. raises concern about FDA standards in pandemic 2020-04-16T04:00:00Z Brazilian researchers ended part of a trial of chloroquine treatment prematurely, when several patients subjected to high doses of the drug began to show heart irregularities. Column: Experts lose enthusiasm for chloroquine coronavirus treatment promoted by Trump 2020-04-13T04:00:00Z After being treated with chloroquine, Wilson shared she felt "completely nauseous" and suffered from vertigo. Rita Wilson opens up about coronavirus symptoms, warns about 'extreme' chloroquine side effects 2020-04-14T04:00:00Z In the United States, one person died after self-medicating with chloroquine, which was touted online as a miracle cure for the coronavirus even though its efficacy is unproven. Burning Cell Towers, Out of Baseless Fear They Spread the Virus 2020-04-10T04:00:00Z Malaria drugs like chloroquine and hydroxychloroquine are the synthetic form of quinine. NOT REAL NEWS: A week of false news around the coronavirus 2020-04-10T04:00:00Z Some chloroquine drugs were already approved by the FDA before the pandemic as antimalarial medications, a process that required plant inspections. Exclusive: Bayer's chloroquine donation to U.S. raises concern about FDA standards in pandemic 2020-04-16T04:00:00Z The chloroquine story, though, demonstrates the limits of discussing misinformation as a social media or critical thinking problem. Trump’s chloroquine hype is a misinformation problem bigger than social media 2020-04-09T04:00:00Z The page adds that "hydroxychloroquine and chloroquine are under investigation in clinical trials." CDC quietly deletes hydroxychloroquine guidance as study hyped by Trump comes into question 2020-04-08T04:00:00Z The updated, and shortened, guidance adds that “Hydroxychloroquine and chloroquine are under investigation in clinical trials” for use on coronavirus patients. CDC removes unusual guidance to doctors about drug favored by Trump 2020-04-07T04:00:00Z Potential side effects of chloroquine and hydroxychloroquine, including heart arrhythmia, are another concern. Trials of drugs to prevent coronavirus infection begin in health care workers 2020-04-07T04:00:00Z The Department of Health and Human Services also cleared hydroxychloroquine and two similar drugs, chloroquine and hydroxychloroquine, for “compassionate use” on extremely ill COVID-19 patients who have exhausted other treatment methods. Bureau of Prisons, VA purchase tens of thousands of dollars worth of anti-malaria drug amid coronavirus crisis 2020-04-07T04:00:00Z Soon after that first appearance, Trump began talking about chloroquine. Trump’s chloroquine hype is a misinformation problem bigger than social media 2020-04-09T04:00:00Z Last month, an Arizona man died after ingesting a non-pharmaceutical form of a related drug — chloroquine phosphate — used to clean aquarium tanks. Opinion | The one word that explains why Trump should not be president 2020-04-06T04:00:00Z The drugs also can cause vision loss called retinopathy with long-term use, and chloroquine has been associated with psychosis. Why does Trump call an 86-year-old unproven drug a game-changer against coronavirus? 2020-04-06T04:00:00Z In addition to curing malaria, chloroquine and hydroxychloroquine are mainstays for patients with lupus and rheumatoid arthritis, Luetkemeyer says. Trials of drugs to prevent coronavirus infection begin in health care workers 2020-04-07T04:00:00Z Last month, an Arizona man died after ingesting a form of the chemical called chloroquine phosphate after hearing Trump discuss the drug at his briefings. Trump blocks Fauci from answering question about unproven drug therapy at coronavirus press briefing 2020-04-06T04:00:00Z In a press conference last month, President Trump and FDA Commissioner Dr. Stephen Hahn described several approaches under testing, such as chloroquine, a drug long used to treat malaria, and remdesivir. Gilead gives update on experimental coronavirus treatment 2020-04-06T04:00:00Z Last month, a man in Arizona died after he and his wife took chloroquine phosphate, an additive used to clean fish tanks that is also found in hydroxychloroquine. Fauci: no evidence anti-malaria drug Trump pushes works against virus 2020-04-06T04:00:00Z Bayer invented the medicine chloroquine in 1934, and it has been used for decades to treat malaria throughout the world. Why does Trump call an 86-year-old unproven drug a game-changer against coronavirus? 2020-04-06T04:00:00Z Doctors are able to prescribe chloroquine in these circumstances as it's a registered drug. Why India could help US get unproven 'corona drug' 2020-04-06T04:00:00Z The president went to the briefing room lectern a short while later and glowed about chloroquine use, suggesting he might even take it himself despite not having symptoms or evidence of the virus. Ignoring Expert Opinion, Trump Again Promotes Use of Hydroxychloroquine 2020-04-05T04:00:00Z Hydroxychloroquine is a less toxic form of chloroquine, one of the most widely prescribed drugs in the world. What the 1918 flu pandemic can teach us about coronavirus drug trials | Laura Spinney 2020-04-05T04:00:00Z Without solid evidence of chloroquine’s efficacy, it is irresponsible to promote anecdotes about its curing Covid-19, as Silicon Valley elites and even President Trump have done. Opinion | What We Pretend to Know About the Coronavirus Could Kill Us 2020-04-03T04:00:00Z Both drugs, chloroquine and hydroxychloroquine, are available as generics, but public and political interest has caused runs, hoarding and severe shortages in recent weeks. Why does Trump call an 86-year-old unproven drug a game-changer against coronavirus? 2020-04-06T04:00:00Z The document describes possible prescription information for coronavirus patients, while at the same time proposing hydroxychloroquine and chloroquine as an option in coronavirus treatment. Exclusive: Pressed by Trump, U.S. pushed unproven coronavirus treatment guidance 2020-04-04T04:00:00Z Meanwhile, the Food and Drug Administration recently announced an emergency-use authorization for several drugs, including hydroxychloroquine and chloroquine, despite a lack of clear evidence of their effectiveness. Dr. Fauci on hydroxychloroquine to treat coronavirus: Be careful before making a 'majestic leap' 2020-04-03T04:00:00Z Established sellers of illegal recreational and prescription drugs on anonymous marketplaces such as Empire and Kingdom have now turned to advertising chloroquine as a cure for Covid-19. Revealed: online trade in coronavirus 'cure', test kits and ventilators 2020-04-03T04:00:00Z In late March, the Food and Drug Administration authorized the use of chloroquine and a related drug, hydroxychloroquine, for emergency use for hospitalized patients. Opinion | What We Pretend to Know About the Coronavirus Could Kill Us 2020-04-03T04:00:00Z Some producers of the malaria drug chloroquine who know Mr. Kushner have invoked his name with administration officials to press for a quicker means of production on the unproven coronavirus treatment promoted by Mr. Trump. Kushner Puts Himself in Middle of White House’s Chaotic Coronavirus Response 2020-04-02T04:00:00Z Last month, an Arizona man died after ingesting a type of fish parasite treatment that listed chloroquine phosphate as one of its ingredients. Touting Virus Cure, ‘Simple Country Doctor’ Becomes a Right-Wing Star 2020-04-02T04:00:00Z An Arizona man died last week after ingesting a fish tank cleaner that contained chloroquine phosphate after hearing Trump promote hydroxychloroquine. Dozens of college professors sign open letter to Murdochs criticizing Fox News' coronavirus coverage 2020-04-02T04:00:00Z Several media organizations that confused the chloroquine medication with chloroquine phosphate later issued corrections. Woman who said she drank fish-tank cleaner because of president's advice is not a Trump supporter 2020-04-02T04:00:00Z But chloroquine is not an approved treatment for the coronavirus, and its side effects include potentially fatal complications. Opinion | What We Pretend to Know About the Coronavirus Could Kill Us 2020-04-03T04:00:00Z The Food and Drug Administration recently announced an emergency-use authorization for several drugs, including hydroxychloroquine and chloroquine, despite a lack of clear evidence of their effectiveness. Dr. Stephen Smith on effectiveness of hydroxychloroquine: 'I think this is the beginning of the end of the pandemic' 2020-04-02T04:00:00Z This week, the F.D.A. issued an emergency use authorization for hydroxychloroquine and chloroquine, allowing doctors to distribute them to coronavirus patients. Touting Virus Cure, ‘Simple Country Doctor’ Becomes a Right-Wing Star 2020-04-02T04:00:00Z Hydroxychloroquine sulfate and chloroquine phosphate are oral prescription drugs approved to treat malaria and other diseases. Michigan reverses course on Trump-touted coronavirus drugs 2020-04-02T04:00:00Z An Arizona man died last week after ingesting a fish tank cleaner that contained chloroquine phosphate after hearing Trump tout the supposed benefits of taking hydroxychloroquine. Tucker Carlson decries Twitter after Fox News colleague's misleading tweet about COVID-19 is deleted 2020-04-02T04:00:00Z On March 25, the Oregon Board of Pharmacy adopted a temporary emergency rule prohibiting the dispensing of chloroquine and hydroxychloroquine “for presumptive treatment or prevention of COVID-19 infection.” Oregon relaxes new restrictions on drugs to fight virus 2020-04-01T04:00:00Z Taking azithromycin with hydroxychloroquine or chloroquine, as some U.S. medical centers are now recommending to treat COVID-19, can exacerbate the situation. Decades-old malaria drug front and center in coronavirus treatment fight 2020-04-01T04:00:00Z An Arizona man died after ingesting a fish tank cleaner that contained chloroquine phosphate after Trump hyped an unproven drug treatment for the new coronavirus in spite of the warnings of Fauci. Devin Nunes again questions social distancing measures despite repeated warnings from experts 2020-04-01T04:00:00Z In response, Hahn said that an emergency-use authorization was implemented “for entry of hydroxychloroquine and chloroquine into the system,” noting that “we did not approve it for the use of treatment of COVID-19.” FDA commissioner on fast-tracking potential treatments for coronavirus 2020-04-01T04:00:00Z Hydroxychloroquine and chloroquine are anti-malarial drugs, while Zithromax, or azithromycin, is an antibiotic. Facebook, Twitter delete some world leaders' posts over false information 2020-03-31T04:00:00Z The spokesman said there was also no evidence either of the positive effects of chloroquine, another malaria drug, which is also being tested for its possible use against COVID-19. No proof drug touted by Trump drug is effective against coronavirus: EU 2020-03-31T04:00:00Z The Food and Drug Administration recently announced an emergency use authorization to try several drugs, including hydroxychloroquine and chloroquine, in an effort to combat COVID-19, despite a lack of clear evidence of their effectiveness. Can hydroxychloroquine prevent COVID-19? Study aims to find answers 2020-03-31T04:00:00Z And hydroxychloroquine and a related compound, chloroquine, are unproven, experimental treatments. World leaders' posts deleted over false virus info 2020-03-31T04:00:00Z There have been a few small, anecdotal studies that show a possible benefit of the drugs — hydroxychloroquine and chloroquine — in relieving the acute respiratory symptoms of covid-19 and clearing the virus from infected patients. Coronavirus pandemic could kill as many as 200,000 in U.S., White House warns 2020-03-30T04:00:00Z New York moved to begin trials last week after procuring 70,000 doses of the drugs and Bayer pharmaceutical company has donated 3 million doses of its brand of chloroquine to the federal government. Editorial Roundup: Excerpts from recent Wisconsin editorials 2020-03-30T04:00:00Z Iran will participate in the World Health Organization’s global megatrial probing the effectiveness of four coronavirus treatments, including a drug combo used against HIV and the antimalarial drug chloroquine. Iran confronts coronavirus amid a ‘battle between science and conspiracy theories’ 2020-03-29T04:00:00Z In a press conference earlier this month, President Trump and FDA commissioner Dr. Stephen Hahn described several approaches under testing, such as chloroquine, a drug long used to treat malaria, and remdesivir. Experimental coronavirus treatment using antiviral remdesivir expanded by developer Gilead 2020-03-30T04:00:00Z Politico reported late Sunday that the drugs included hydroxychloroquine and chloroquine. FDA Oks emergency authorization of drugs touted by Trump to fight coronavirus 2020-03-29T04:00:00Z The Michigan Department of Licensing and Regulatory Affairs issued an order Wednesday warning physicians against writing prescriptions “without a legitimate medical purpose” and instructing pharmacists to evaluate the “legitimacy” of hydroxychloroquine or chloroquine prescriptions. Governor blasted for hydroxychloroquine crackdown as political debate escalates 2020-03-29T04:00:00Z Given that, Trump should use the Defense Production Act of 1950 to ramp up production of the chloroquine drugs immediately and allow patients to sign waivers to get the drugs. Editorial Roundup: Excerpts from recent Wisconsin editorials 2020-03-30T04:00:00Z A recent review of research on chloroquine as a treatment for COVID-19 concluded that “it seems to be effective in limiting the replication” of the novel coronavirus in laboratory dishes. Risks of using malaria drugs off-label to treat COVID-19 2020-03-28T04:00:00Z Over time, synthetic versions were developed, including a drug called chloroquine, which was created in the midst of World War II in an effort to spare overseas American troops from malaria. After Trump suggests hydroxychloroquine as potential COVID-19 cure, lupus patients face shortages 2020-03-28T04:00:00Z He also mentioned the death of an Arizona man who recently “died after he and his wife consumed a form of chloroquine, a drug that Mr. Trump has promoted on the air.” Success of Trump's daily coronavirus briefings has media changing tune, critics say 2020-03-27T04:00:00Z Several drugs, including chloroquine, showed the ability to block coronaviruses from infecting cells in vitro. Could Chloroquine Treat Coronavirus? 2020-03-27T04:00:00Z New York will use three medications — hydroxychloroquine and chloroquine in combination with the antibiotic azithromycin — contributed by the Federal Emergency Management Agency and Amneal Pharmaceuticals, the state said. Trump keeps touting an unproven coronavirus treatment. It’s now being tested on thousands in New York. 2020-03-26T04:00:00Z Both chloroquine and hydroxychloroquine failed to help patients infected with the dengue and chikungunya viruses, and it also failed to protect against the flu. Risks of using malaria drugs off-label to treat COVID-19 2020-03-28T04:00:00Z Mr. Sisolak, a Democrat, signed an emergency order Tuesday limiting doctors from prescribing chloroquine and hydroxychloroquine, which are commonly used to treat malaria, for the novel coronavirus to patients in a hospital setting. Ted Cruz accuses Nevada governor of ‘partisan politics’ for limiting drug touted by Trump 2020-03-26T04:00:00Z What the Times’ media reporter failed to mention is that the man drank fish tank cleaner that happened to include a form of chloroquine, which had obviously not been prescribed by a doctor. Success of Trump's daily coronavirus briefings has media changing tune, critics say 2020-03-27T04:00:00Z While there’s a lot of hype around the anti-malaria medication chloroquine, there’s still no evidence it — or any other drug — actually works. Everything you need to know about the coronavirus 2020-03-26T04:00:00Z Yet evidence from pending studies will certainly lag massive off-label use of chloroquine and hydroxychloroquine given the presidential endorsement. ‘This is insane!’ Many scientists lament Trump’s embrace of risky malaria drugs for coronavirus 2020-03-26T04:00:00Z He took his chloroquine, the anti-malaria drug that Trump kept talking up, hoping that it might protect him against the virus, though there is no evidence that it will. He urged saving the economy over protecting those who are ‘not productive’ from the coronavirus. Then he faced America’s wrath. 2020-03-25T04:00:00Z The Texas State Board of Pharmacy order adopted March 20 limits prescriptions of four drugs, including chloroquine, hydroxychloroquine and azithromycin, to 14 days, but does not restrict their use to inpatients only. Ted Cruz accuses Nevada governor of ‘partisan politics’ for limiting drug touted by Trump 2020-03-26T04:00:00Z Hydroxychloroquine is a less toxic derivative of chloroquine. Search for coronavirus treatments: The latest developments 2020-03-25T04:00:00Z But while scientists are working to test the efficacy of the malaria drugs chloroquine and hydroxychloroquine in fighting coronavirus, there’s currently no reliable, published, peer-reviewed evidence on the subject. How to spot fake coronavirus news on social media 2020-03-25T04:00:00Z Hydroxychloroquine, sold under the brand name Plaquenil, is approved to treat lupus and rheumatoid arthritis while chloroquine is an anti-malarial treatment. Doctors are hoarding unproven COVID-19 medications 2020-03-25T04:00:00Z Mr. Trump said in the meeting, should promote chloroquine treatment, two senior administration officials said. Oracle Providing White House With Software to Study Unproven Coronavirus Drugs 2020-03-24T04:00:00Z Some of them — including chloroquine and hydroxychloroquine — are commonly used to treat malaria, lupus, rheumatoid arthritis and other conditions. States Say Some Doctors Stockpile Trial Coronavirus Drugs, for Themselves 2020-03-24T04:00:00Z “We’ve also been working with manufacturers overseas,” said Pence, who added that he’s personally spoken to the CEO of Bayer Pharmaceuticals about producing more chloroquine. Search for coronavirus treatments: The latest developments 2020-03-25T04:00:00Z After hearing the president’s remarks, an Arizona man ingested chloroquine phosphate, a fish tank cleaner, in an effort to prevent covid-19, and died shortly after. Oracle to partner with Trump administration to collect data on unproven drugs to treat covid-19 2020-03-24T04:00:00Z This weekend Brooks cared for a man in his 60s who died after ingesting a version of chloroquine commonly used to clean fish tanks. Doctors are hoarding unproven COVID-19 medications 2020-03-25T04:00:00Z An Arizona man died Tuesday after ingesting a fish tank cleaner that contained chloroquine phosphate. Lou Dobbs: Trump "was right and frankly Fauci was wrong” about unproven drug treatments for COVID-19 2020-03-24T04:00:00Z In response, Pence said, “The good news is, the chloroquine medication, we actually deployed in the state of New York resources to be able to be administered to the people.” Pence: FDA approving 'off-label' use for hydroxychloroquine to help coronavirus patients 2020-03-24T04:00:00Z She said the name sounded familiar, because she previously used a cleaner containing chloroquine to treat her koi fish for parasites. Man dies from ingesting cleaner containing chloroquine after Trump hypes treatment for coronavirus 2020-03-24T04:00:00Z Soon after a US man died after he began drinking chloroquine because he was scared of getting sick. Decades-old drug in two Australian trials related to Covid-19 but experts urge caution 2020-03-24T04:00:00Z Chloroquine, also known as chloroquine phosphate, is a drug normally used to prevent or treat malaria caused by mosquito bites in countries where the disease is most common. What is chloroquine? 2020-03-24T04:00:00Z So chloroquine and hydroxychloroquine are both malaria drugs. Is Trump's much-touted chloroquine really a "game changer" for COVID-19? Not exactly 2020-03-23T04:00:00Z “I want to assure you, there is no barrier to access the chloroquine in this country. We’re working to add to that supply even as we speak.” Pence: FDA approving 'off-label' use for hydroxychloroquine to help coronavirus patients 2020-03-24T04:00:00Z After Trump's briefing, Nigeria reported two fatal overdoses of chloroquine. Man dies from ingesting cleaner containing chloroquine after Trump hypes treatment for coronavirus 2020-03-24T04:00:00Z “To date there are no clear indications that chloroquine or hydroxychloroquine are a treatment option. Additional clinical trials will tell us whether hydroxychloroquine or chloroquine are viable options for Covid-19 treatments.” Decades-old drug in two Australian trials related to Covid-19 but experts urge caution 2020-03-24T04:00:00Z Brooks urged the medical community to not prescribe chloroquine medication to any non-hospitalized patients. Arizona man dies after taking chloroquine for coronavirus 2020-03-23T04:00:00Z Despite the limited evidence available, public figures, including Elon Musk and Trump, are pushing the message that hydroxychloroquine and chloroquine are the solutions to the outbreaks. Scientists are racing to find the best drugs to treat COVID-19 2020-03-23T04:00:00Z Fauci pushed back a bit more assertively on Trump's assertion that chloroquine is safe, based on decades of use for malaria. Trump's most dangerous flim-flam: False hope and quack advice 2020-03-23T04:00:00Z At the same time, the state said it was actively seeking ways to combat the virus, buying large batches of three drugs — hydroxychloroquine, azithromycin and chloroquine — and aiming to begin drug trials this week. Coronavirus in N.Y.C.: Region Is Now an Epicenter of Global Pandemic 2020-03-22T04:00:00Z One worry for trial leaders is that chloroquine has been given so much publicity that patients may refuse to be “randomized” and accept a 50 percent chance of being given a placebo. The Virus Can Be Stopped, but Only With Harsh Steps, Experts Say 2020-03-22T04:00:00Z That trial will test the same drugs, with the exception of chloroquine. WHO launches global megatrial of the four most promising coronavirus treatments 2020-03-22T04:00:00Z About two dozen clinical trials are already underway in China to test chloroquine’s efficacy against the novel coronavirus. Coronavirus drugs: Where we are and what we know 2020-03-21T04:00:00Z As far back as 2005, the National Institutes of Health’s National Center for Biotechnology Information published a laboratory study that said chloroquine could be a “potent” remedy for SARS. NBC article touted ‘promising’ drug as its reporter bashed Trump for ‘false sense of hope’ 2020-03-21T04:00:00Z Trump said at a White House press briefing Thursday that chloroquine and hydroxychloroquine will be made available to test whether it helps patients recover from coronavirus. Trump renews calls for agencies to ‘move fast’ on potential coronavirus treatments 2020-03-21T04:00:00Z The president – who repeatedly downplayed the threat early in the global outbreak – has this week been hyping an anti-malarial drug, chloroquine, as a possible therapeutic treatment. Trump throws tantrum over coronavirus question: 'You're a terrible reporter' 2020-03-21T04:00:00Z At a press conference on Friday, President Donald Trump called chloroquine and hydroxychloroquine a “game changer.” WHO launches global megatrial of the four most promising coronavirus treatments 2020-03-22T04:00:00Z As you may guess, this drug is closely related to chloroquine. Coronavirus drugs: Where we are and what we know 2020-03-21T04:00:00Z One study is testing chloroquine to try to protect health care workers at highest risk of infection, because a vaccine is probably a year or more away. AP FACT CHECK: Trump’s breathless takes on drugs for virus 2020-03-21T04:00:00Z Another generic company, Rising Pharmaceuticals, manufacturers both hydroxychloroquine and chloroquine. Hospitals and doctors are wiping out supplies of an unproven coronavirus treatment 2020-03-20T04:00:00Z Many Nigerian households still use tablets containing chloroquine for treating malaria even though it was banned in 2005. Has Trump approved malaria drug for treating coronavirus? 2020-03-20T04:00:00Z FDA Commissioner Stephen Hahn, speaking after the president, said the FDA is considering giving chloroquine to larger populations of coronavirus patients as part of an “expanded use” testing program. Trump calls anti-malaria drug a ‘game-changer’ for coronavirus, but the FDA says it needs study 2020-03-19T04:00:00Z Like chloroquine, scientists suspect it might help to mitigate cytokine storms. Coronavirus drugs: Where we are and what we know 2020-03-21T04:00:00Z But after Trump spoke, FDA Commissioner Stephen Hahn clarified that chloroquine would first need to be tested for use on the virus. Amid coronavirus clampdown, Americans urged not to travel abroad; Italy surpasses China in deaths 2020-03-19T04:00:00Z One study is testing chloroquine to try to protect health care workers at highest risk of infection, because a vaccine is likely a year or more away. AP FACT CHECK: Trump falsely claims drug approval for virus 2020-03-19T04:00:00Z It's been reported that Lagos is now dealing with a spate of people being poisoned from overdoses of chloroquine. Has Trump approved malaria drug for treating coronavirus? 2020-03-20T04:00:00Z That study found that use of chloroquine and its tablets is showing favorable outcomes in humans infected with coronavirus, including faster time to recovery and shorter hospital stays, she said Monday. In coronavirus fight, Trump 'leaving no stone unturned,' Alex Azar says 2020-03-19T04:00:00Z Doctors are testing it in COVID-19 patients on the theory that if chloroquine is helpful, hydroxychloroquine might be too, and recent lab results seem to back that up. Coronavirus drugs: Where we are and what we know 2020-03-21T04:00:00Z Some Chinese doctors are also trying chloroquine, an antimalarial drug, which is off-patent, therefore cheap and highly available, and would be very useful in low-income countries. Coronavirus facts: is there a cure and what is the mortality rate of the virus? 2020-03-13T04:00:00Z There’s a lot of interest in chloroquine, and interferon with Kaletra. ‘We thought she was going to pass away.’ Did an experimental drug help a U.S. coronavirus patient? 2020-03-13T04:00:00Z A third drug, the antimalarial chloroquine, which was being used in China, was not in trials, the WHO said. Doctors look to HIV and Ebola drugs for coronavirus cure 2020-02-20T05:00:00Z The anti-malaria drug chloroquine phosphate is being tested in 10 hospitals in China in more than 100 patients. Factbox: Global efforts to develop vaccines, drugs to fight the coronavirus 2020-02-19T05:00:00Z Trump’s request that the FDA investigate chloroquine included hydroxychloroquine as well. Coronavirus drugs: Where we are and what we know 2020-03-21T04:00:00Z A more unorthodox remedy being tested against the coronavirus in China is chloroquine. Doctors fight coronavirus outbreak with drugs that target HIV, malaria and Ebola 2020-02-13T05:00:00Z One of the more unorthodox remedies being tested against the coronavirus in China is chloroquine. To Fight Coronavirus Outbreak, Doctors Deploy Drugs Targeting HIV, Malaria And Ebola 2020-02-13T05:00:00Z Figure 1 | Mutations affect the transport of antimalarial drugs through the PfCRT protein. a, The drugs chloroquine and piperaquine target a membrane-bound organelle in the malaria parasite, called the digestive vacuole. Malaria parasites fine-tune mutations to resist drugs 2019-11-26T05:00:00Z In the 1990s, chloroquine was the first line treatment, but malaria parasites grew resistant to it. Genomic Surveillance Is a Key Weapon in the Fight Against Malaria 2019-04-25T04:00:00Z There, I learned about the arrival of chloroquine resistance from Cambodia with the large numbers of resulting deaths. We Need to Stop Drug-Resistant Malaria at its Source, Right Now 2019-01-31T05:00:00Z These outbreaks were made worse by the fact that Plasmodia had developed resistance to chloroquine and other antimalarial drugs then in use. Could Ancient Remedies Hold the Answer to the Looming Antibiotics Crisis? 2016-09-14T04:00:00Z In the study, 82 percent of mice with cerebral malaria that were treated just with parasite-killing chloroquine died, compared with only 35 percent of those treated with chloroquine combined with irbesartan, a blood-pressure drug. Common Blood-Pressure Drug May Work on Malaria, Too 2016-09-19T04:00:00Z Then officials began an intensive public health campaign, relying on DDT to kill mosquitoes and chloroquine to cure the disease. ‘Big Success Story’: Sri Lanka Is Declared Free of Malaria 2016-09-12T04:00:00Z Malaria used to be treated with chloroquine or quinine. This Ancient Chinese Remedy Helped Win the Nobel Prize 2015-10-05T04:00:00Z The researchers discovered that the extended artemisinin treatment caused the parasites to develop tolerance to most of the drugs — including quinine, chloroquine, and mefloquine. Resistance to popular malaria drugs helps parasites survive other treatments 2015-09-16T04:00:00Z As a result, half of the pharmaceutical supplies of Sudan were destroyed, in particular their malaria medicine, chloroquine. Scoring the Noam Chomsky/Sam Harris debate: How the professor knocked out the atheist 2015-05-07T04:00:00Z Scientists are particularly concerned about the declining efficacy of artemisinin because it appears to follow a pattern seen in previously used malaria drugs, like chloroquine. Key Malaria Drug Is Losing Efficacy, Researchers Find 2015-02-19T05:00:00Z Dr Woodrow told the BBC: "The evidence from the global spread of chloroquine resistance is this translates to a large increase in the number of cases and a higher number of deaths." Resistant-malaria 'enormous threat' 2015-02-19T05:00:00Z Beginning in the 1950s, the drug chloroquine became increasingly available and death rates from malaria began to drop significantly in Africa. This Ancient Chinese Remedy Helped Win the Nobel Prize 2015-10-05T04:00:00Z When the first malaria drug, chloroquine, was developed, researchers thought that the disease would be eradicated within years. Malaria resistance genetics revealed 2015-01-19T05:00:00Z That, according to Behe, accounts for the very low frequency of chloroquine resistance and validates his analysis. The Key To Evolution: Multiple Mutational Pathways In Sequence 2014-12-21T05:00:00Z The anti-malarial drug chloroquine causes some people to itch — especially people of African ancestry — and studying itch cells made from their fibroblasts could help to explain why, she adds. Pain and itch neurons grown in a dish 2014-11-24T05:00:00Z If artemisinin becomes ineffective, malaria experts say, it would be a disaster equivalent to losing chloroquine, a former “miracle cure.” A Quiet Approach to Bringing Down Malaria 2014-10-20T04:00:00Z From these trials emerged a new malaria drug called chloroquine. Plagues on the Poor: What Ebola Can Learn From Malaria 2014-10-02T04:00:00Z These included two also identified in the first study: the antimalarial drug chloroquine and the antipsychotic chlorpromazine. Existing Drugs May Work Against MERS, Studies Suggest 2014-05-19T04:00:00Z Mothers were as likely to look to traditional teas to treat the illness, which, like chloroquine, occasionally seemed to work. Annals of the Malaria War: Move over Angelina Jolie 2013-10-22T22:45:02.450Z The nightmare scenario, however, is a repeat of what took place in the 1980s, with what was then the most commonly used anti-malarial drug, chloroquine. Can Asia save Africa from drug-resistant malaria? 2012-11-23T02:21:48Z Instead, shops sold cheaper but often ineffective drugs such as chloroquine — or, worse, artemisinin monotherapies, which are a recipe for the emergence of drug resistance. Too much to ask 2012-11-21T18:20:03.247Z From the 1950s to 1970, through the WHO Global Malaria Eradication Programme, people in poor countries took chloroquine like aspirin. Plagues on the Poor: What Ebola Can Learn From Malaria 2014-10-02T04:00:00Z Instead, many people end up with less expensive but ineffective drugs such as chloroquine and artemisinin monotherapies, which increase the risk of drug resistance. Global Fund Changes Malaria Program, Ends Passionate Debate 2012-11-16T21:45:11Z It turned out, chloroquine was losing its efficacy across the continent. Annals of the Malaria War: Move over Angelina Jolie 2013-10-22T22:45:02.450Z Resistance to chloroquine emerged in South East Asia, spread, and when it reached Africa, the number of malaria cases rose sharply. Can Asia save Africa from drug-resistant malaria? 2012-11-23T02:21:48Z With both chloroquine and sulfadoxine-pyrimethamine, resistance spread to the Indian subcontinent and eventually Africa. Drug development: Holding out for reinforcements 2012-04-25T17:21:20.517Z But chloroquine failed to solve the malaria problem because nature found a way around it—the parasites that cause the disease developed resistance. Plagues on the Poor: What Ebola Can Learn From Malaria 2014-10-02T04:00:00Z They also developed drugs like chloroquine, used for several decades before being replaced when malarial parasites began showing resistance to it. F.Y.I.: Answers to Questions About New York 2012-01-28T05:05:24Z He’d give mothers the drug chloroquine to cure malaria, but their children often died anyways. Annals of the Malaria War: Move over Angelina Jolie 2013-10-22T22:45:02.450Z Malaria rebounded in the 1970s when mosquitoes became resistant to pesticides and the parasites that cause the disease became resistant to chloroquine. Global Update: W.H.O. Reports 25 Percent Drop in Malaria Deaths in a Decade 2011-12-26T19:46:54Z Two 2009 studies found that chloroquine, an inexpensive malaria drug, worked in the laboratory, but it later failed in hamsters and ferrets. Global Update: Antibody for Hendra and Nipah Viruses Shows Promise 2011-10-24T20:55:42Z The malarial parasites responsible for the epidemic had evolved resistance to chloroquine, the most common antimalarial drug. Malaria on the Rise as East African Climate Heats Up 2011-04-01T18:15:00.220Z If chloroquine is not an option, a second choice might be mefloquine, according to Pasternak. No birth defect risk seen with malaria drug 2011-02-16T19:15:08Z With DDT and chloroquine, it drove that down to 18 cases by 1963. Global Update: Malaria: A Disease Close to Eradication Grows, Aided by Political Tumult in Sri Lanka 2010-12-27T20:46:37Z The researchers were seeking a replacement for the anti-malaria medication chloroquine, having discovered that malaria strains in several regions of the globe had developed a resistance. Toxic Cocktail: Army Struggles With Mental-Health Care 2010-09-17T16:32:00Z This was one of the reasons that malaria parasite developed resistance to chloroquine and now the drug is virtually ineffective. Could selling cheap malaria drugs in private stores harm children's health? 2010-08-17T15:17:00Z By the late 1960s, the malaria toll had surged back to over 300 million, only now many malarial mosquitoes were resistant to DDT and malaria parasites inured to the drug chloroquine. Malaria's Tenacious Buzz 2010-07-09T22:09:00Z Resistance to chloroquine and sulfadoxine-pyrimethamine, the cheapest malaria drugs, is common. U.S. effort to fight malaria focuses on women 2010-04-23T02:08:00Z Sceptics fear that middlemen will pocket the subsidy, or that there will be leakage to other markets; some fret that 50 cents is too pricey to compete with chloroquine for people earning $1 a day. 2010-01-07T10:42:00Z AMFm aims to sell ACTs at a similar price to chloroquine but it is unclear what measures will be in place to ensure that ACTs will be protected from a similar fate. Could selling cheap malaria drugs in private stores harm children's health? 2010-08-17T15:17:00Z |
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