单词 | CFTR |
例句 | The symptoms of CF result from a malfunctioning membrane ion channel called the cystic fibrosis transmembrane conductance regulator, or CFTR. Anatomy and Physiology 2013-06-19T00:00:00Z On its own, the molecule wouldn’t be enough to restore the function of F508del CFTR. Cystic fibrosis drugs target the malformed proteins at the root of the disease 2020-07-28T04:00:00Z This molecule seems to inhibit the action of RAC1, a protein that regulates CFTR. The gender gap in cystic fibrosis 2020-07-28T04:00:00Z Cystic fibrosis is caused by mutations in a gene known as CFTR. Opinion | Persistence pays off in treatment for cystic fibrosis 2019-11-23T05:00:00Z Scientists have long known that the disease stems from a faulty version of protein called CFTR. New techniques let scientists zero in on individual cells 2019-03-03T05:00:00Z The researchers, from Mass General and Broad, initially studied both healthy and CFTR–mutated mice. Newly Discovered Cell Type May Fuel Cystic Fibrosis 2018-08-02T04:00:00Z “As we’ve gotten more and more aware of the different properties of CFTR, nothing is simple,” says Garry Cutting, a clinical geneticist at Johns Hopkins University in Baltimore, Maryland. Cystic fibrosis drugs target the malformed proteins at the root of the disease 2020-07-28T04:00:00Z People with the disease lack a working version of CFTR, the protein responsible for regulating chloride transport. The gender gap in cystic fibrosis 2020-07-28T04:00:00Z Cystic fibrosis results from mutations in a gene that produces a tube-shaped protein known as CFTR, essential to the balance of electrolytes in the body. Cystic Fibrosis Might Be Two Diseases 2014-07-21T04:00:00Z The studies identified a type of rare cell in the airway that makes large amounts of CFTR, surpassing earlier but only dimly understood indications that such cells existed. New techniques let scientists zero in on individual cells 2019-03-03T05:00:00Z And several institutions in the United Kingdom, working with Genzyme, a biotech company also based in Cambridge, are trying to use gene therapy to help the cell to express normal CFTR. Drug bests cystic-fibrosis mutation 2012-02-08T18:50:31.840Z |
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