| 单词 | cell death |
| 例句 | But they didn’t know what effects any of this would have on humans: Would it cause cellular changes, or even cell death? The Immortal Life of Henrietta Lacks 2010-02-02T00:00:00Z In animal models, decreasing or blocking the production of niacin in the brain promotes neuronal damage and cell death. Diet can influence mood, behavior and more — a neuroscientist explains 2022-09-09T04:00:00Z They mutate uncontrollably, evade cell death and take up excessive resources at the expense of the other cells. How microbes in food can impact your body’s defenses against cancer 2023-02-28T05:00:00Z Maybe it was just cell death, but I was beginning to understand why people did this. A $1,000 Day in Moscow for $100 2016-07-26T04:00:00Z These include controlled cell division, proper cell death, resource sharing, division of labor and protection of the extracellular environment. How microbes in food can impact your body’s defenses against cancer 2023-02-28T05:00:00Z Cells monitor themselves for mutations and induce cell death, also known as apoptosis, when necessary. How microbes in food can impact your body’s defenses against cancer 2023-02-28T05:00:00Z We found that 24 to 48 hours of intermittent fasting by mice provided protection against cell death in specific regions of their brain. Intermittent fasting could help protect the brain from age-related diseases like Alzheimer’s 2023-06-29T04:00:00Z Liu said: “All cells need to communicate and these communications get jammed up, and CBD tries to correct this by restoring them. This ultimately results in these cells being able to undergo cell death.” Study looks at cannabis ingredient's ability to help children's tumours 2017-05-02T04:00:00Z We therefore sought to find out if dietary interventions, particularly intermittent fasting, would counteract the accumulation of amyloid-ß in the brain and potentially safeguard against age-related brain cell death. Intermittent fasting could help protect the brain from age-related diseases like Alzheimer’s 2023-06-29T04:00:00Z A visiting lecturer in the US, she also took a PhD studying cell death. The childlike vision of Claerwen James 2013-02-10T00:05:00Z "The machinery for cell death appears to be repurposed to clear out bad mitochondria," observed Joshi. Zen and the art of mitochondrial maintenance: The machinery of death makes a healthier life 2023-11-08T05:00:00Z This prevents the cell death that would otherwise set in, as is often observed after activation of the NLRP3 inflammasome and subsequent pore formation. Immune system: Mechanisms of alarmin release discovered 2023-11-02T04:00:00Z This abnormal division can lead to tumor cell death. Common chemotherapy drugs don't work like doctors thought, with big implications for drug discovery 2023-10-26T04:00:00Z This new ability to trigger programmed cell death could open the door for improved cancer treatments. Researchers identify 'switch' to activate cancer cell death 2023-10-23T04:00:00Z When they reduced TUG1 expression in cancer cells, they found severe DNA damage and cell death. Brain tumor treatment by targeting TUG1, a gene that controls replication stress 2023-10-12T04:00:00Z These cause cell death, and are commonly found in the brains of Alzheimer's patients. Graphene oxide reduces the toxicity of Alzheimer's proteins 2023-10-04T04:00:00Z To explore how plants deal with toxic protein aggregation, Dr Ernesto Llamas, first author of the study, and colleagues introduced the toxic mutant protein huntingtin in plants, which causes cell death in human neurons. Plant chloroplasts promise potential therapy for Huntington's disease 2023-10-02T04:00:00Z If ER stress becomes chronic, as is the case in many neurological diseases, it can cause cell death. A promising drug candidate for ALS -- prolongs lifespan and eases symptoms in rats and mice 2023-09-22T04:00:00Z Death receptors do precisely what their name implies -- when targeted, they trigger programmed cell death of tumor cells. Researchers identify 'switch' to activate cancer cell death 2023-10-23T04:00:00Z The photo-oxidants induce a unique form of cancer cell death that can overcome cancer cell resistance. Novel photo-oxidation therapy for anticancer treatment 2023-09-20T04:00:00Z Flies with too much autophagy had massive cell death leading to visible degeneration of the eye. Gene links exercise endurance, cold tolerance, and cellular maintenance in flies 2023-09-18T04:00:00Z Prof De Strooper says the discovery that blocking the MEG3 molecule can hold off brain cell death could lead to a "whole new line of drugs development". Scientists discover how brain cells die in Alzheimer’s 2023-09-15T04:00:00Z Though it is safe to the touch, a death cap contains amatoxins, which prevent cells from creating proteins, ultimately causing cell death and organ failure. Death cap mushrooms are extremely deadly—and they’re spreading 2023-08-31T04:00:00Z The oral medication carries radioactive particles directly to the cancer cell particles to cause cell death. Prostate cancer: All hands on deck for treatment success | Provided by Providence Swedish 2023-08-24T04:00:00Z After metamorphosis, these organs become redundant and will be resorbed by controlled cell death, called apoptosis. Fundamentals of Biology 2015-01-01T00:00:00Z In addition, the damaged version of p53 found in cancer cells cannot trigger cell death. Concepts of Biology 2013-04-25T00:00:00Z The coronavirus infects beta cells in the pancreas that make insulin, Dr. Davis said, and cause cell death. Covid May Increase the Risk of Type 2 Diabetes, Researchers Find 2023-04-18T04:00:00Z This finding parallels our earlier work identifying these factors as regulators of a protein complex that controls cell death and inflammation in response to LPS. How sepsis can lead to cell death 2023-01-01T05:00:00Z Many in the field believe it is responsible for the brain cell death that robs people of memories and ultimately kills them, although deposits of the protein are also found in brains of healthy people. Scientists tie third clinical trial death to experimental Alzheimer’s drug 2022-12-21T05:00:00Z Extreme deficiencies may result in leaves showing signs of cell death. Fundamentals of Biology 2015-01-01T00:00:00Z After the NK cell detects an infected or tumor cell, it induces programmed cell death, or apoptosis. Concepts of Biology 2013-04-25T00:00:00Z Interactions between the protein encoded by APOE4 and sticky plaques of amyloid—a substance tied to brain cell death—in the brain partially explain the connection. This Is How an Alzheimer’s Gene Ravages the Brain 2022-11-18T05:00:00Z Senescent cells resist apoptosis, or programmed cell death, and characteristically get big and flat, with enlarged nuclei. Zombie cells central to the quest for active, vital old age 2022-08-30T04:00:00Z High doses cause significant cell death in all systems, but the lowest doses that cause fatalities do so by weakening the immune system through the loss of white blood cells. College Physics for AP Courses 2015-08-12T00:00:00Z For example, genes involved in cellular growth and controlled cell death, when disturbed, could lead to the growth of cancerous cells. Biology for AP Courses 2022-06-09T00:00:00Z Viral replication within a living cell always produces changes in the cell, sometimes resulting in cell death and sometimes slowly killing the infected cells. Concepts of Biology 2013-04-25T00:00:00Z Glutamate typically excites neurons, playing key roles in learning and memory, but too much of it can wreak havoc on brain function, causing problems ranging from cell death to seizures. Mentally exhausted? Study blames buildup of key chemical in brain 2022-08-11T04:00:00Z He died three days later after developing a brain injury due to cell death from lack of oxygen. Los Angeles police officer’s training death ruled accidental 2022-07-28T04:00:00Z The cell can commit suicide, known as programmed cell death. College Physics for AP Courses 2015-08-12T00:00:00Z A granzyme is a protease that digests cellular proteins and induces the target cell to undergo programmed cell death, or apoptosis. Biology for AP Courses 2022-06-09T00:00:00Z The process of programmed cell death is called apoptosis. Miller & Levine Biology 2018-01-01T00:00:00Z This can lead to mutations and cell death. Environmental Biology 2018-09-06T00:00:00Z The link between cell death in the fusiform gyrus and the symptom is relatively easy to understand. Anatomy and Physiology 2013-06-19T00:00:00Z In the brains of mice, sleep deprivation led to cell death after a few days of sleep restriction — a much lower threshold for brain damage than previously thought. The Sleep Debt Collector is Here 2022-06-24T04:00:00Z This response can take many different forms, including protein synthesis, a change in cell metabolism, cell division and growth, or even cell death. Biology for AP Courses 2022-06-09T00:00:00Z One of the most promising venom-derived drugs to date comes from the deadly Fraser Island funnel web spider of Australia, which halts cell death after a heart attack. Deadly Venom From Spiders and Snakes May Also Cure What Ails You 2022-05-03T04:00:00Z So the structure of the olfactory system has just been totally decayed away because of that significant cell death. COVID Smell Loss and Long COVID Linked to Inflammation 2022-02-07T05:00:00Z Apoptosis is programmed cell death, a normal step-by-step process that destroys cells no longer needed by the body. Anatomy and Physiology 2013-06-19T00:00:00Z "The coach told my source, 'It's a sickle cell death,'" Anderson reported. Football's unknown epidemic: When Black players die suddenly, the cover-up begins 2021-11-13T05:00:00Z Explain the function of telomerase in the development of stem cells and cancer cells, and the inhibition of telomerase in programmed cell death or apoptosis. Biology for AP Courses 2022-06-09T00:00:00Z Blood flow to the heart is reduced after a heart attack, which makes the cell environment more acidic and leads to cell death. Deadly Venom From Spiders and Snakes May Also Cure What Ails You 2022-05-03T04:00:00Z Moreover the researchers found that even without smoke specifically drifting into eyes, corneas can come to harm: this iron-driven cell death occurred even when cells were exposed to other types of tobacco products. Cigarette Smoke Kills Eye Cells 2021-10-18T04:00:00Z During the sixth week, the distal end of the limb bud becomes paddle-shaped, and selective cell death separates the developing fingers and toes. Anatomy and Physiology 2013-06-19T00:00:00Z Because lobsters almost never get tumors, Polinski says, the team expected to find many more genes linked to activating programmed cell death. How do most lobsters stay cancer-free? Newly sequenced genome could reveal their secrets 2021-06-23T04:00:00Z Both forms appear to be involved in initiating controlled cell death mechanisms in normal cells. Biology for AP Courses 2022-06-09T00:00:00Z They also showed less gene activity related to cell death. Will Probiotics Save Corals or Harm Them? 2021-05-27T04:00:00Z Taken together, these signs indicated that exposing corneal cells to the tobacco products had induced a form of programmed cell death driven by iron called ferroptosis. Cigarette Smoke Kills Eye Cells 2021-10-18T04:00:00Z These are events in which a physical blockage may be temporary, cutting off the blood supply and oxygen to a region, but not to the extent that it causes cell death in that region. Anatomy and Physiology 2013-06-19T00:00:00Z They might also reveal the origins of cardiac problems like congenital heart defects in babies and cardiac cell death after heart attacks, Mendjan says. Lab-grown minihearts beat like the real thing 2021-05-20T04:00:00Z However, in colon cancer cells, expression of the long form results in increased cell growth instead of cell death. Biology for AP Courses 2022-06-09T00:00:00Z The researchers are endowing the cells with healthy copies of the gene for wolframin or the gene for a protein that reduces ER stress to determine whether they restore cellular function and reduce cell death. The race to treat a rare, fatal syndrome may help others with common disorders like diabetes 2021-02-11T05:00:00Z These mutations inactivate genes that usually help to guard against cancer, such as those responsible for repairing DNA damage or controlling programmed cell death. The RNA and protein landscape that could bring precision medicine to more people 2020-09-22T04:00:00Z Within the paddle, areas of tissue undergo cell death, producing separations between the growing fingers and toes. Anatomy and Physiology 2013-06-19T00:00:00Z Genetic analysis of the trees’ vascular cambium — a thin layer of cells that lies just underneath the bark, and creates new living tissue — showed “no evidence of senescence,” or cell death, the authors wrote. Can Trees Live Forever? New Kindling for an Immortal Debate 2020-07-27T04:00:00Z A loss of enzymes would result in cell death. Biology for AP Courses 2022-06-09T00:00:00Z Instead, the symptoms stem from widespread cell death. The race to treat a rare, fatal syndrome may help others with common disorders like diabetes 2021-02-11T05:00:00Z For that reason, he thinks that the main source of ribosomes floating independently in the extracellular space would be from cell death. The biologist on the hunt for extracellular ribosomes 2020-06-16T04:00:00Z Cells at the center of this interzone region undergo cell death to form the joint cavity, while surrounding mesenchyme cells will form the articular capsule and supporting ligaments. Anatomy and Physiology 2013-06-19T00:00:00Z Closer to reality are actual efforts to slow biological processes to a fraction of their normal rate by replacing blood with ice-cold saline to prevent cell death in severe trauma. Switch in Mouse Brain Induces a Deep Slumber Similar to Hibernation 2020-06-15T04:00:00Z Blocking glycolysis in RBCs causes imbalance in the membrane potential, leading to cell death. Biology for AP Courses 2022-06-09T00:00:00Z “We think that excess calcium is leading to excess cell death,” Ehrlich says. The race to treat a rare, fatal syndrome may help others with common disorders like diabetes 2021-02-11T05:00:00Z These changes are ultimately followed by cell death and brain degeneration, which prompted suspicions that beta-amyloid was a cause. A Harder Look at Alzheimer’s Causes and Treatments 2020-04-29T04:00:00Z Mesenchyme cells at the margins of the interzone will give rise to the articular capsule, while cell death at the center forms the space that will become the joint cavity of the future synovial joint. Anatomy and Physiology 2013-06-19T00:00:00Z These changes are accompanied by inflammation and cell death in the brain. For Alzheimer’s researchers, a long and frustrating struggle to find a drug 2020-04-03T04:00:00Z Further, if a cell is infected with a virus, the cell can signal itself to undergo programmed cell death, killing the virus in the process. Biology for AP Courses 2022-06-09T00:00:00Z Slowly evolving genes were involved in DNA repair, cell cycle control, cell death, and immunity, all of which are mechanisms to prevent cancer cell formation and proliferation. A Quest for the Genetic Fountain of Youth 2020-03-26T04:00:00Z Ever since the original description of apoptosis4, it has been known that this form of cell death does not trigger an inflammatory response, as occurs in other types of cell death, such as necrosis. Ghostly metabolic messages from dying cells 2020-03-17T04:00:00Z Free radicals are reactive because they contain free unpaired electrons; they can easily oxidize other molecules throughout the cell, causing cellular damage and even cell death. Anatomy and Physiology 2013-06-19T00:00:00Z The interferons trigger cascades of antiviral activity, from shutting down host protein synthesis to inducing cell death. How Coronaviruses Cause Infection—from Colds to Deadly Pneumonia 2020-02-05T05:00:00Z Programmed cell death, or apoptosis, removes damaged or unnecessary cells and plays a vital role in development, including morphogenesis of fingers and toes. Biology for AP Courses 2022-06-09T00:00:00Z As a result of the mutation, the now-cancerous cell fails to undergo programmed cell death and instead divides uncontrollably and independently of normal cell cycle control mechanisms. A Quest for the Genetic Fountain of Youth 2020-03-26T04:00:00Z Marley’s ghost appears in chains that he said were forged in life; what other chains are forged in cell death? Ghostly metabolic messages from dying cells 2020-03-17T04:00:00Z Hypoxia involving cardiac muscle or brain tissue can lead to cell death and severe impairment of brain or heart function. Anatomy and Physiology 2013-06-19T00:00:00Z Some cancers hijack important cell-signalling pathways, such as those involved in cell death or proliferation. Step aside CRISPR, RNA editing is taking off 2020-02-03T05:00:00Z Apoptosis, or programmed cell death, is an important step in the development of xylem. Biology for AP Courses 2022-06-09T00:00:00Z To understand the disease-causing mechanisms, the authors isolated liver cells from the animals, and found that cell death in response to cytolysin exposure was dose-dependent. Microbial clues to a liver disease 2019-11-12T05:00:00Z The navy assay checks only for bacterial cell death; it does not reveal which receptors are targeted. Phage Therapy Could Beat Drug-Resistant Illnesses 2019-11-05T05:00:00Z These proteins enhance cellular proliferation and inhibit apoptosis, or programmed cell death. Anatomy and Physiology 2013-06-19T00:00:00Z First, patient-derived neurons treated with each of the compounds showed significantly less shrinkage, degeneration of neuronal projections and cell death than was seen in untreated neurons. Strategy to selectively remove mutant proteins could combat neurodegeneration 2019-10-29T04:00:00Z If the DNA cannot be repaired, p53 can trigger apoptosis, or cell death, to prevent the duplication of damaged chromosomes. Biology for AP Courses 2022-06-09T00:00:00Z This surprising finding that cell death supports the survival of senescent cells highlights the complexity of cell-death regulation in multicellular animals. Senescent cells feed on their neighbours 2019-10-27T04:00:00Z Figure 1 | A pathway that blocks cell death. A powerful cell-protection system prevents cell death by ferroptosis 2019-10-20T04:00:00Z They eventually showed that the mutant cells were forced to initiate a form of programmed cell death called apoptosis. These secret battles between your body’s cells might just save your life 2019-10-14T04:00:00Z Terazosin may help by activating an enzyme called PGK1 to prevent this brain cell death, the researchers, from the University of Iowa, in the US and the Beijing Institute for Brain Disorders, China, say. Prostate drug may slow Parkinson's disease 2019-09-16T04:00:00Z A loss of triglycerides would result in cell death. Biology for AP Courses 2022-06-09T00:00:00Z Numerous mechanisms of cell death occur in animal tissues. Senescent cells feed on their neighbours 2019-10-27T04:00:00Z Sometime after plaques appear, another protein named tau starts forming tangles inside neurons, heralding cell death and memory loss. Scientists rethink Alzheimer’s, diversifying the drug search 2019-09-10T04:00:00Z Chemotherapy usually works by inducing DNA damage that leads to cell death. A dynamic view of chemotherapy effectiveness 2019-08-04T04:00:00Z Loser cells undergo a type of cell death called apoptosis, and the initiation of cell death requires direct contact between winner and loser cells. Flower power as human cancer cells compete with normal cells 2019-07-23T04:00:00Z This response can take many different forms, including protein synthesis, a change in the cell’s metabolism, cell growth, or even cell death. Biology for AP Courses 2022-06-09T00:00:00Z These include forms of cell suicide, such as apoptosis, which leads to the fragmentation of individual cells, and regulated forms of necrotic cell death that induce cell rupture7. Senescent cells feed on their neighbours 2019-10-27T04:00:00Z To help primate IPS cells thrive, his Stanford team and collaborators endowed them with a gene that prevents cell death. Embryo experiments take ‘baby steps’ toward growing human organs in livestock 2019-06-26T04:00:00Z What’s more, these areas were found to be rich in markers of cell death, or cells with DNA damage. Mystery of why arteries harden may have been solved, say scientists 2019-06-11T04:00:00Z If infected by viruses, bacteria harbouring abortive-infection systems enter a dormant state or trigger cell death, which provides a population-level antiviral defence. Bacterial dormancy curbs phage epidemics 2019-05-28T04:00:00Z Programmed cell death, or apoptosis, is important for removing damaged or unnecessary cells. Biology for AP Courses 2022-06-09T00:00:00Z Cells that are uncooperative because they are damaged or dysfunctional, and that pose a threat, are either eliminated by cell death or undergo a usually irreversible growth arrest called senescence1. Senescent cells feed on their neighbours 2019-10-27T04:00:00Z Any one of many cellular insults may accelerate neurons toward earlier cell death. There won’t be a cure for Alzheimer’s disease in our lifetime 2019-05-19T04:00:00Z "Tau is one of my favourite proteins, where there's tau there's cell death in the brain," says Prof Spires-Jones. Dementia is 'greatest health challenge' 2019-05-02T04:00:00Z The system reduced cell death, preserved anatomical integrity, and restored circulatory, metabolic and some cellular functions. Brain Restoration System Explores Hazy Territory between Being Dead or Alive 2019-04-19T04:00:00Z He stressed that the revivifying system the researchers developed, which they dubbed BrainEx, may not reverse cell death and restore brains to what would be considered a stable, living state. Scientists restore some brain cell functions in pigs four hours after death 2019-04-17T04:00:00Z This fluid contained a host of nutrients as well as other substances to tackle processes that lead to cell death, and the circulation was continued for six hours. Researchers 'reboot' pig brains hours after animals died 2019-04-17T04:00:00Z Second, that, unless circulation is quickly restored, there is a largely irreversible progression towards cell death and the death of the organism. Part-revived Pig Brains Raise Slew of Ethical Quandaries 2019-04-17T04:00:00Z Second, that, unless circulation is quickly restored, there is a largely irreversible progression towards cell death and the death of the organism1. Part-revived pig brains raise slew of ethical quandaries 2019-04-16T04:00:00Z The study, published in the journal Nature, showed a reduction in brain cell death, the restoration of blood vessels and some brain activity. Pig brains partially revived after death 2019-04-17T04:00:00Z I'm very optimistic that we'll be able to get to the beginning of that highway where the cell death process starts. Nobel Laureate Paul Greengard Kept Churning Out Ideas for New Drugs after Turning 90 2019-04-15T04:00:00Z Brenner shared in the 2002 Nobel Prize in Physiology or Medicine for deciphering the genetics of programmed cell death and animal development, including how the nervous system forms. Sydney Brenner (1927-2019) 2019-04-10T04:00:00Z This feat, accomplished so far for no other animal, made clear that many cells are programmatically killed during development, leading to the discovery by H. Robert Horvitz of the phenomenon of programmed cell death. Sydney Brenner, a Decipherer of the Genetic Code, Is Dead at 92 2019-04-05T04:00:00Z It blocked the ubiquitin system in cells, causing proteins to build up to dangerous levels and eventually trigger cell death. Protein-slaying drugs could be the next blockbuster therapies 2019-03-19T04:00:00Z It seems to result from the increased rate of cell death that accompanies the rapid cellular proliferation inside tumours — the dying cells release fragments of genomic DNA that enter the bloodstream. Towards the better diagnosis of lymphoma 2018-11-13T05:00:00Z Moreover, increasing neurogenesis in the earliest stages of the disease may protect against neuronal cell death later in the disease, providing a potentially powerful disease-modifying treatment strategy. How Exercise Might "Clean" the Alzheimer's Brain 2018-10-16T04:00:00Z Tumours in the brains of both groups are nourished by networks of blood vessels and peppered with pockets of cell death. The unexpected role of histones in childhood brain cancer 2018-09-25T04:00:00Z The topic assumed an importance that transcended worm biology when it emerged that programmed cell death is supposed to occur in damaged human cells, and that cancer can thwart this process. Sydney Brenner, a Decipherer of the Genetic Code, Is Dead at 92 2019-04-05T04:00:00Z Macular degeneration is the result of photoreceptor cell death in the retina. Blue light from your phone may be permanently damaging your eyes 2018-09-21T04:00:00Z Autopsies showed telltale signs of heart injury and cell death. Opinion | Why Your Cardiologist Should Ask About Your Love Life 2018-09-14T04:00:00Z One tactic is blocking programmed cell death, which plants use to stop the spread of infection by killing tainted cells. Searching for Chocolate's Roots, and Enemies, in Colombia's Wilderness 2018-09-15T04:00:00Z Necroptosis is a more inflammatory form of cell death than apoptosis. Neighbourhood deaths cause a switch in cancer subtype 2018-09-11T04:00:00Z However, in cancer cells, pathway activation causes an increase in cell proliferation and a reduction in cell death, rather than affecting blood-glucose regulation. Diet boosts the effectiveness of a cancer drug 2018-08-05T04:00:00Z Many researchers believe the accumulation of amyloid beta in the brain leads to cell death and Alzheimer’s. Alzheimer’s Drug Shows Benefit, But Some Experts Say More Testing Needed 2018-07-25T04:00:00Z The initiation of cell death by NPS results in a minimal inflammatory response, which improves healing outcomes and supports the replacement of treated tissue cells with healthy tissue cells. Pulse Biosciences Announces Treatment of First Patients in Study to Evaluate the Safety and Efficacy 2018-07-10T04:00:00Z After valve repair in healthy hearts, the contractile cells typically enter a deactivated state called quiescence, or are cleared from the region by programmed cell death. Taking bioengineered heart valves from faulty to functional 2018-07-01T04:00:00Z Based on these findings, he says, “they really do seem distinct, which probably means that the mechanisms of cell death are different.” Analysis of a Million-Plus Genomes Points to Blurring Lines Among Brain Disorders 2018-06-22T04:00:00Z They indicate that cannabinoids may inhibit tumor growth by blocking cell growth, causing cell death and blocking the development of blood vessels that tumors require to grow. Cannabis versus Cancer 2018-05-02T04:00:00Z Red lines indicate cell death and loss of yolk sac vascularization phenotype. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis 2018-04-24T04:00:00Z These clock genes are particularly important in cancer because they govern cell cycles, cell proliferation, cell death and DNA damage repair — all processes that can go haywire in cancer. Medicine’s secret ingredient — it’s in the timing 2018-04-16T04:00:00Z On his return home to the Massachusetts Institute of Technology in Cambridge, Horvitz discovered genes that regulate programmed cell death. John Sulston (1942–2018) 2018-03-18T04:00:00Z He shared his Nobel Prize with Sydney Brenner and H. Robert Horvitz for “their discoveries concerning genetic regulation of organ development and programmed cell death.” John E. Sulston, Nobel-winning scientist who helped decode human genome, dies at 75 2018-03-10T05:00:00Z This was down to an increase in cell death and fewer cells multiplying. Ibuprofen taken in early pregnancy could affect daughter's fertility – study 2018-02-01T05:00:00Z Green line indicates mild cell death phenotype without loss of yolk sac vascularization. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis 2018-04-24T04:00:00Z Previous experimental studies in animals have suggested that ginkgo biloba protects against the nerve cell death associated with blood clots in the brain, possibly by increasing blood flow in the cerebral arteries. Herbal remedy 'may aid stroke recovery' 2017-12-18T05:00:00Z When this interaction is suppressed in human cells in culture, cell death occurs. A transfer-RNA-derived small RNA regulates ribosome biogenesis 2017-11-28T05:00:00Z Another contains drugs that aim to quell inflammation and prevent cell death. Drug development: Sprint finish Ferrostatins inhibit oxidative lipid damage and cell death in diverse disease models. Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition 2017-10-31T04:00:00Z Long-term or chronic inflammation is particularly damaging to brain cells and ultimately leads to brain cell death. Here's What We Think Alzheimer's Does to the Brain 2017-11-06T05:00:00Z They identified six signalling pathways that prevent cell death, which senescent cells activate to survive12, 13. To stay young, kill zombie cells 2017-10-23T04:00:00Z Dale initially tried using genes from other plants and even a worm to reprogram the Cavendish not to succumb to the cell death that TR4 induces. Bananapocalypse: The race to save the world’s most popular fruit 2017-10-06T04:00:00Z Palytoxin jams the pump, throwing ion ratios out of whack. “This sustained ionic imbalance condition leads to cell death,” Tubaro said. Homegrown coral reefs are beautiful — and potentially dangerous 2017-07-28T04:00:00Z Traumatic brain injuries, which cause cell death and inflammation in the brain, affect 2 million Americans each year. Memory-enhancing drug reverses effects of traumatic brain injury in mice 2017-07-10T04:00:00Z This is what is responsible for the cell death in the brain – and we think its due to a build up of two types of protein, called amyloid and tau. Here's What We Think Alzheimer's Does to the Brain 2017-11-06T05:00:00Z Sulston’s maps paved the way for discoveries surrounding programmed cell death and small, regulatory RNA molecules. The trickiest family tree in biology 2017-07-04T04:00:00Z “Zika triggers this catastrophe of inflammation and cell death,” Tully said. In Lacey, a Washington mom grapples with baby’s Zika-caused birth defects 2017-06-18T04:00:00Z Once locked on to a cancer cell, the drug disrupts its chemistry by blocking the action of a key molecule, causing widespread DNA damage and cell death. Drug shrinks ovarian tumours in early trial - BBC News 2017-06-03T04:00:00Z The MIT team also found no markers indicating that the electric fields caused abnormal inflammation, DNA damage, or cell death in the targeted tissue. Electric fields tease buried brain cells into action 2017-06-01T04:00:00Z Victorious neurons receive trophic, or nourishing, factors that allow their survival; unsuccessful neurons fade away in a process called apoptosis, or cell death. Why Is Synaptic Pruning Important for the Developing Brain? 2017-05-29T04:00:00Z Meanwhile, other groups developed new ways of killing bacteria with vancomycin: One alteration found a novel way to halt cell wall construction, whereas another caused the outer wall membrane to leak, leading to cell death. Superantibiotic is 25,000 times more potent than its predecessor 2017-05-30T04:00:00Z The authors show that compressive stresses induced by orientational ordering and defects in the epithelium provide a physical trigger for cell death. Biological physics: Liquid crystals in living tissue : Nature : Nature Research 2014-04-11T04:00:00Z After 24 h, cells were stained with 7-AAD to determine cell death. Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens : Nature : Nature Research 2017-03-21T04:00:00Z While the former may reflect the response of tumour cells to tissue injury and cell death, the latter is reminiscent of normal intestinal tissue regeneration after damage27. A distinct role for Lgr5+ stem cells in primary and metastatic colon cancer : Nature : Nature Research 2017-03-28T04:00:00Z The timing of cell death is genetically programmed and occurs at different points in the embryonic development of each species. Why Is Synaptic Pruning Important for the Developing Brain? 2017-05-29T04:00:00Z In the study, published in the journal Cell, scientists used a compound designed to knock senescent cells out of their state of suspended animation, towards cell death. Purging the body of 'retired' cells could reverse ageing, study shows 2017-03-23T04:00:00Z The second form of cell death is autophagy, in which the cell turns on itself, changing its defective or redundant components into nutrients, which can be used by other cells. What Our Cells Teach Us About a ‘Natural’ Death 2017-03-13T04:00:00Z Rekhtman’s project examines the potential of immunogenic cell death in cancer treatment, which he explained as training “the immune system to recognize and kill cancer cells.” These teens are working to cure cancer and solve the mysteries of the universe 2017-02-12T05:00:00Z A postmortem revealed structural damage, increased cell death, and other abnormalities in the mice’s brains. Critics assail paper claiming harm from cancer vaccine 2016-12-21T05:00:00Z It clumps together to form sticky plaques and is thought to cause nerve cell death and memory loss. 'Flashing light therapy' for Alzheimer's - BBC News 2016-12-07T05:00:00Z The fungus Pseudocercospora fijiensis attacks the plants’ leaves, causing cell death that affects photosynthesis and leads to a reduction in fruit production and quality. The banana as we know it is in imminent danger 2016-10-25T04:00:00Z The ugliest and least elegant form of cell death is necrosis, in which because of either a lack of food or some other toxic injury, cells burst open, releasing their contents into the serums. What Our Cells Teach Us About a ‘Natural’ Death 2017-03-13T04:00:00Z These plaques are thought to cause brain cell death. Animal Study Hints at Gene Therapy's Possible Promise for Alzheimer's 2016-10-10T04:00:00Z As cells age, telomeres gradually break down, eventually resulting in cell death, a normal part of growth and aging, the study authors explained. Acne's Silver Lining: Slower Aging of the Skin? 2016-09-29T04:00:00Z The drug, Emricasan, inhibits a natural process that causes programmed cell death. 3 Drugs Identified to Potentially Fight Zika Virus 2016-08-29T04:00:00Z Calcium plays a crucial role in cell death, she said, and high levels of calcium in the blood might prompt the early death of neurons. Calcium Supplements Might Raise Older Women's Dementia Risk 2016-08-18T04:00:00Z This form of cell death occurs when food supply is limited but not entirely cut off, such as in heart failure. What Our Cells Teach Us About a ‘Natural’ Death 2017-03-13T04:00:00Z Insufficient blood flow to the brain that leads to cell death. NINA RADCLIFF: Stroke prevention and treatment 2016-05-11T04:00:00Z In healthy humans, this and other enzymes contribute to “programmed cell death,” necessary so cells do not divide or grow endlessly, like cancerous cells. A Window Into the Workings of Zika 2016-05-09T04:00:00Z Researchers also found "significant" cell death of neurons in the part of the brain that plays a role in sight, hearing and language, researchers said. Ultrasounds missed her Zika infection–until one showed serious harm to her fetus 2016-03-30T04:00:00Z Assays spot cell death from diabetes, cancer, and more. Tests of blood-borne DNA pinpoint tissue damage | Science 2016-03-17T04:00:00Z The most sophisticated form of cell death, however, is unlike the other two types. What Our Cells Teach Us About a ‘Natural’ Death 2017-03-13T04:00:00Z What’s more, it was found to interfere with cell processes and to increase cell death. Zika virus: scientists a step closer to establishing microcephaly link 2016-03-04T05:00:00Z Not only did this lead to massive cell death, but the infected cells were reprogrammed to produce even more copies of the Zika virus. How the Zika virus is probably causing birth defects in children 2016-03-04T05:00:00Z Leukotrienes contribute to neural inflammation, cell death and the unnecessary activation of the brain's immune cells, microglia, which can damage healthy neurons. Ageing: Restoration project : Nature : Nature Publishing Group 2016-03-01T05:00:00Z Assays spot cell death from diabetes, cancer, and more. Tests of blood-borne DNA pinpoint tissue damage | Science 2016-03-17T04:00:00Z Apoptosis, a Greek word used to describe falling leaves, is a programmed form of cell death. What Our Cells Teach Us About a ‘Natural’ Death 2017-03-13T04:00:00Z It reduces the rate at which cells are lost both through wear and tear and through the programmed process of cell death called apoptosis. We all know exercise makes you live longer. But this will actually get you off the couch. 2016-02-22T05:00:00Z The expert dismissed the specks as junk—the detritus of mass cell death. The Stem-Cell Scandal 2016-02-29T05:00:00Z In experiments on worms, University of Cambridge researchers identified drugs which prevented the very first step towards brain cell death. Alzheimer's preventative drug hope - BBC News 2016-02-12T05:00:00Z According to a study published by Cell Death Discovery, a synthetic sandalwood called Sandalore promotes cell death in cancer cells for patients with myeloid leukemia. This Scent Could Cure Leukemia 2016-02-01T05:00:00Z In fact, most cancers occur because of defects in apoptosis, and most novel cancer therapies are designed to allow cell death to occur as it normally would. What Our Cells Teach Us About a ‘Natural’ Death 2017-03-13T04:00:00Z Cycles of programmed cell death establish the developmental clock in plant roots. Cyclic programmed cell death stimulates hormone signaling and root development in Arabidopsis | Science 2016-01-21T05:00:00Z As people age, telomeres shorten, eventually leading to cell death, according to the U.S. Having More Kids May Slow Mom's Aging, Study Says 2016-01-13T05:00:00Z Using therapeutic hypothermia, his body was cooled to reduce cell death and protect his brain. EXCHANGE: Doctor saved after collapsing at fitness center 2016-01-09T05:00:00Z The disease causes cell death in the macula, the part of the eye that allows you to see fine detail needed for reading and driving. Carrots (and other brightly colored fruits and veggies) really do aid vision 2015-10-12T04:00:00Z They found that while the elephant and human cells repaired DNA at a similar rate, elephant cells underwent significantly more cell death—which is one way a body fights cancer. What Elephants Can Teach Us About Cancer Treatment 2015-10-08T04:00:00Z Cycles of programmed cell death establish the developmental clock in plant roots. Cyclic programmed cell death stimulates hormone signaling and root development in Arabidopsis | Science 2016-01-21T05:00:00Z In bacteria, this disrupts the outer layer, damaging the genetic material and cell machinery, which can lead to cell death. The bacteria-fighting super element making a return to hospitals: Copper 2015-09-20T04:00:00Z But David Vaux, who studies cell death at the Walter and Eliza Hall Institute of Medical Research in Melbourne, Australia, and who raised concerns about the paper with Nature, says the paper should be retracted. Welfare breach prompts Nature to update policy on publishing animal experiments 2015-09-15T04:00:00Z Researchers suggest it is the accumulation of these waste products that triggers cell death. Brain cells 'burn out' in Parkinson's disease - BBC News 2015-08-27T04:00:00Z The prison cell death just weeks ago of Sandra Bland, an African American woman arrested after she failed to use her turn signal, also weighed heavily on the convention. Hillary Clinton takes a shot at Jeb Bush on race in front of black activists 2015-07-31T04:00:00Z Under normal circumstances, a cell that goes berserk is quickly eliminated through a mechanism called programmed cell death, or cellular suicide. Cellular Cheaters Give Rise to Cancer 2015-07-27T04:00:00Z After the scans, the research did show an increase in DNA damage in cells, as well as cell death. Cell Damage Occurs When People Have CT Scans: Study 2015-07-22T04:00:00Z It is thought the formation of sticky plaques of amyloid between nerve cells leads to damage and eventually brain cell death. Dementia drug data set to be revealed - BBC News 2015-07-21T04:00:00Z The probe into the jail cell death of Sandra Bland will be treated as a murder investigation, a Texas district attorney said Monday. Sandra Bland's death will be investigated as murder: District attorney 2015-07-20T04:00:00Z Strokes are caused by a lack of blood flow to parts of the brain, causing tissue damage and cell death. Think Like a Doctor: Strange Vision 2015-06-04T04:00:00Z Namenda works by increasing the level of glutamate in the brain and is thought to interfere with cell death. The Last Day of Her Life 2015-05-14T04:00:00Z Secondly, some animal studies have some that various pesticides can cause an increase in rates of apoptosis, or programmed cell death, in the gonads, leading to fewer sperm being produced. Pesticides on Vegetables and Fruit Linked to Lower Sperm Counts 2015-03-30T04:00:00Z “If we removed the liver component we no longer observed this cell death in the lung tissue,” says Shuler. Artificial organs: Honey, I shrunk the lungs : Nature : Nature Publishing Group 2015-03-24T04:00:00Z When amyloid is present, it somehow opens the door for tau to spread to other parts of the brain, causing widespread cell death and cognitive decline. Harvard prevention trial studies tau, Alzheimer's other protein 2015-03-03T05:00:00Z Research suggests eating raspberries may help prevent illness by inhibiting abnormal division of cells, and promoting normal healthy cell death. The 50 Healthiest Foods of All Time (With Recipes) 2015-03-02T05:00:00Z “It is also particularly vulnerable to cell death in settings of inadequate cell energy.” Another Strike Against Trans Fats: They're Bad For The Brain, Study Finds 2014-11-19T05:00:00Z Study first author Gretchen Thomsen, a scientist in Svendsen's laboratory, added that, "It is likely that dysfunction at a cellular level, without cell death, goes undetected for years prior to symptom onset and clinical diagnosis." Mouse Study Suggests Brain Is Damaged Early in Lou Gehrig's Disease 2014-11-11T05:00:00Z The previous reigning paradigm, Tanzi says, involved a whole “black box” of events caused by amyloid—including inflammation, oxidative stress and more—that eventually led to tangles and cell death. Alzheimer’s in a Petri Dish Could Revolutionize Research "In this new system that we call 'Alzheimer's-in-a-dish,' we've been able to show for the first time that amyloid deposition is sufficient to lead to tangles and subsequent cell death," Tanzi said. Scientists Inch Closer to Alzheimer's Origins 2014-10-12T04:00:00Z “In this new system that we call ‘Alzheimer’s-in-a-dish,’ we’ve been able to show for the first time that amyloid deposition is sufficient to lead to tangles and subsequent cell death,” said Tanzi in a statement. Researchers Watch Alzheimer's Disease Unfold in a Lab Dish for the First Time 2014-10-13T04:00:00Z When they fail, less energy is created and cell death results. EXCHANGE: 3-year-old lives with chronic conditions 2014-09-27T04:00:00Z A possible reason is that cell death disrupts the structure of retinal tissue, leading to a domino-like decline. Curing blindness: Vision quest 2014-09-09T04:00:00Z When the particles are excited by x-rays they generate high concentrations of reactive oxygen species – chemically reactive molecules that cause significant damage to cell structures leading to cell death. Nanoparticles could help deliver a killer blow to cancer 2014-08-13T04:00:00Z There was biological evidence to support the association as well – bisphosphonates were also correlated with lower rates of cell death and hampered cancer cell activity. More Bad News For Osteoporosis Drugs: They Don't Prevent Breast Cancer 2014-08-11T04:00:00Z Researchers think the therapy works by slowing the production of harmful substances in the brain and the rate of brain cell death. Cooling babies 'halts brain damage' 2014-07-10T04:00:00Z Mammalian cells also contain specialized structures called organelles, and are programmed to form organized assemblies and to launch cell death. Synthetic biology: How best to build a cell 2014-05-06T04:00:00Z Slowing metabolism — and thus oxygen use — would delay or eliminate the formation of molecules that cause inflammation and cell death, he says. Elephant Seals Reveal Anti-Inflammatory Secrets of Carbon Monoxide 2014-05-02T16:23:00Z Over the years, the lab has improved cell survival by a factor of 100, but the cell death rate is still high. ‘Very big deal’: UW team uses stem cells to fix monkey hearts 2014-05-01T05:46:42Z The small RNAs used in the trial, delivered with little modification, triggered cell death through an immune pathway that can be activated by any RNA more than 21 bases long. RNA interference rebooted 2014-04-23T17:20:25.691Z The results, says Watson, were typical of those expected of an oestrogen mimic: inappropriate activation of oestrogen responses, disruption of normal oestrogen-response pathways, and eventual cell death. Toxicology: The plastics puzzle 2014-04-16T17:21:06.648Z Both modifications result in uncontrolled actin polymerization, collapse of the cytoskeleton and ultimately to cell death. Mechanism of Tc toxin action revealed in molecular detail 2014-04-04T18:24:45.845Z In humans, when oxygen-rich blood floods back into tissues, it prompts an onslaught of chemical reactions that cause inflammation, cell death and even tissue necrosis. Elephant Seals Reveal Anti-Inflammatory Secrets of Carbon Monoxide 2014-05-02T16:23:00Z When a major vessel that supplies blood to the brain becomes obstructed, capillary blood flow is interrupted, and this may deplete the brain's oxygen supply, causing rapid loss of neuronal function, cell death and stroke. Vascular biology: Brain vessels squeezed to death 2014-04-04T18:23:16.270Z The blockbuster chemotherapy drug paclitaxel is widely presumed to cause cell death in tumors as a consequence of mitotic arrest, as it does at concentrations routinely used in cell culture. [Research Articles] Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles 2014-03-26T19:25:11.015Z Trying to protect animals from one form of cell death may lead to death by another. [Report] Activity of Protein Kinase RIPK3 Determines Whether Cells Die by Necroptosis or Apoptosis 2014-03-20T18:26:37.247Z Both modifications result in uncontrolled actin polymerization, collapse of the cytoskeleton and ultimately to cell death. Mechanism of Tc toxin action revealed in molecular detail 2014-04-04T18:24:45.845Z Initially considered an unregulated response to nonspecific stress, necroptosis is now understood to be controlled by signaling pathways that intersect with the regulation of apoptosis, a well-characterized programmed cell death mechanism. [Perspective] RIPK3 Takes Another Deadly Turn 2014-03-20T18:25:34.961Z Mice bred to produce high levels of a protein called amyloid precursor protein—involved in the development of Alzheimer’s disease—had higher rates of nerve cell death in their noses compared to normal mice. 7 Weird Signs of Health Troubles 2014-02-23T12:35:28Z Instead, cells in these lower concentrations of drug proceed through mitosis without substantial delay and divide their chromosomes on multipolar spindles, resulting in chromosome missegregation and cell death. [Research Articles] Cytotoxicity of Paclitaxel in Breast Cancer Is due to Chromosome Missegregation on Multipolar Spindles 2014-03-26T19:25:11.015Z However, incomplete DSB repair by recombination activates a checkpoint that triggers cell death. [Report] Reversal of Female Infertility by Chk2 Ablation Reveals the Oocyte DNA Damage Checkpoint Pathway 2014-01-30T19:26:12.333Z Both modifications result in uncontrolled actin polymerization, collapse of the cytoskeleton and ultimately to cell death. Mechanism of Tc toxin action revealed in molecular detail 2014-04-04T18:24:45.845Z Determining how a cell succumbs to one form of cell death and not the other may guide the development of therapeutic strategies for acute and chronic inflammatory diseases. [Perspective] RIPK3 Takes Another Deadly Turn 2014-03-20T18:25:34.961Z The accumulation of incomplete HIV DNA transcripts in the cytoplasm of these cells, which do not themselves become productively infected, is somehow sensed, which triggers cell death. [Report] IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV 2014-01-23T19:26:36.416Z To their shock, the vast majority of cell death was among the resting, non-virus-replicating cells. New studies detail how HIV affects immune system, claim drug exists to block virus 2013-12-19T21:53:36Z In the paper published in Science, the Gladstone team identified a mechanism that detects the damaged cells and triggers this cell death pathway. Twin U.S. studies unlock mystery of how HIV causes AIDS 2013-12-19T20:02:55Z Concentrations of calcium within mitochondria are tightly regulated and modulate physiological mitochondrial functions, including control of metabolism and cell death. [Report] EMRE Is an Essential Component of the Mitochondrial Calcium Uniporter Complex 2013-12-12T19:27:00.019Z Programmed necrosis, or necroptosis, is a form of cell death with important roles in many inflammatory conditions, such as innate antiviral responses and atherosclerosis. [Perspective] RIPK3 Takes Another Deadly Turn 2014-03-20T18:25:34.961Z Based on their findings, they concluded that DIM induces a DNA repair response and blocks cell death. Broccoli Chemical Saves Mice from Radiation Death 2013-10-15T05:18:00Z Or they realize something was very wrong, and perform a clean programmed cell death called apoptosis. New studies detail how HIV affects immune system, claim drug exists to block virus 2013-12-19T21:53:36Z Other categories enriched in the most convergent genes are related to vesicle-mediated transport, regulation of cell cycle and cell death. Genome-wide signatures of convergent evolution in echolocating mammals 2013-10-09T17:21:23.207Z In addition to certain chemotherapies leading to neutropaenia, the type and context of cell death induced may be crucial for the success of combinations. Influence of tumour micro-environment heterogeneity on therapeutic response 2013-09-18T17:22:26.223Z But it also plays a role in cell proliferation and differentiation—as well as in cell death. How Octopus Arms Regenerate With Ease 2013-08-28T13:15:03.783Z "Many of the trees show highly abnormal growth forms reflecting the effects of mutations and cell death resulting from radiation exposure." Chernobyl's legacy recorded in trees 2013-08-09T00:50:27Z However, calcium widely affects all cells in the body, and the study’s author Li suggested calcium-channel blockers may increase cancer risk because they prevent programmed cell death of abnormal cells. Study ties blood-pressure drugs to breast cancer in older women 2013-08-06T18:17:06Z The propagation of cell death in worms is a model for understanding death in higher order animals “during injury from stroke, infection or mechanical injury like a bone-break or a stab,” Gems explains. Glowing, Glowing, Gone: Cell Fluorescence Casts Light on How Death Spreads Throughout Body 2013-08-02T14:45:03.653Z Testosterone affects the developing brain by downregulating the culling process—the cell death. Touching a Nerve : Exploring the Implications of the Self as Brain, Part 1 [Excerpt] 2013-07-26T14:45:03.867Z Height is associated with increased milk intake in childhood, and higher levels of insulinlike growth factor, which promotes cell growth and inhibits programmed cell death, the authors noted. Cancer risk in women increases with height, study finds 2013-07-26T00:04:11Z They noted that Alzheimer’s disease results from the death of brain cells, while cancer results from uncontrolled cellular growth and resistance to cell death. People with Alzheimer’s are less likely to get cancer, and vice versa 2013-07-15T20:22:21Z This form of cell death keeps birds from sprouting teeth. Why Did the Chicken Lose Its Penis? 2013-06-06T21:15:15.507Z When the researchers looked at the patterns gene activity in the embryos, they found that the cell death was linked to the switching on of a gene called Bmp4. ScienceShot: The Bird's Disappearing Penis 2013-06-06T18:15:00Z In a slightly different part of the hypothalamus—an area shown in rats to be important for ovulation—the neurochemical dopamine inhibits cell death. Touching a Nerve : Exploring the Implications of the Self as Brain, Part 1 [Excerpt] 2013-07-26T14:45:03.867Z The body responds by sending oxygen to this region of the ear, leading to oxidative cell death. Sonic Science: The High-Frequency Hearing Test 2013-05-23T14:15:00.227Z Part of the problem is the inability of ice to preserve the health of the livers – about 2,000 are disposed of each year because of damage due to insufficient oxygen and other cell death. New Device Keeps Liver Alive Outside Body 2013-05-01T21:38:45Z We know that stress can cause cell death of various types, could telomerase help? Increasing telomerase to save you from stress 2013-03-25T12:45:05.043Z If the peptide is clipped — by an enzyme associated with cell death, for example — and the gold particles slip farther apart, their colour changes. Biomedicine: The new gold standard 2013-03-13T18:21:23.433Z Why is there any cell death in a developing brain? Touching a Nerve : Exploring the Implications of the Self as Brain, Part 1 [Excerpt] 2013-07-26T14:45:03.867Z They tested drugs and druglike compounds to find ones that inhibit hair cell death in the fish. Researchers Home in on Biological Ways to Restore Hearing [Excerpt] 2013-02-15T11:15:03.257Z After analyzing the data, the Wake Forest Baptist researchers identified the cell signaling pathway by which epinephrine, a hormone also known as adrenaline, sets off the cellular chain reaction that controls cell death. New Study Shows How Stress Feeds Cancer Cells 2013-01-29T16:51:54Z "It essentially kills you in this explosion of cell death," she told AP. Lottery winner 'slain by cyanide' 2013-01-08T03:52:58Z Huntington's is a fatal, hereditary illness that causes a cascade of cell death in the brain's basal ganglia region. Sheep Help Scientists Fight Huntington s Disease 2012-12-16T15:15:00.180Z Rather than ceasing to divide, the cells of blind mole rats reach a point at which they die en masse in a bout of cell suicide that Gorbunova and her co-authors call “concerted cell death”. Cancer Immunity Insights Might Derive from Study of Blind Mole Rats 2012-11-05T23:15:00.120Z Currently, no known drugs reliably halt or reverse such staggering cell death in people, although some drugs are thought to protect neurons from degradation. To Combat Alzheimer's, Scientists Genetically Reprogram One Kind of Brain Cell Into Another 2012-10-04T17:45:12.103Z Some evidence suggested that large numbers of these cells died through a process of programmed cell death called apoptosis. In Theory: Under Stress, Insulin-Making Cells Revert to Nascent State 2012-10-01T15:20:39Z It borrows an idea from stem cell researchers: adding mouse cells for nourishment, plus a chemical that prevents cell death to an ordinary lab culture medium. 350 surgeries: Bizarre tumor case may lead to custom cancer care 2012-09-26T21:23:27Z In COPD, the shower of free radicals overwhelms these antioxidants, causing cell death and tissue damage. Biochemistry: A radical treatment 2012-09-26T17:22:26.337Z But, counter-intuitively, this mass cell death might be the very thing that makes the animals so long-lived: it could be a natural mechanism their bodies use to clear precancerous cells, stopping tumors in their tracks. Cancer Immunity Insights Might Derive from Study of Blind Mole Rats 2012-11-05T23:15:00.120Z In each case, the team noted whether the gene enhanced or inhibited cell death. A Wrinkle in Slime: Cell Deaths Form Biofilm Folds 2012-09-24T20:00:00Z One of the first things they found was that the CC domain is vital for cell death. How Barley Protects Against Invasion 2012-07-16T14:15:12.883Z However, it is also reminiscent of the fact that mitochondria themselves can have apparently contradictory roles in cells, acting both as metabolic powerhouses as well as initiators of cell death. Dynamic Mitochondrial Networks in Cancer 2012-03-29T15:45:03.977Z Cancer results from mutations in genes that normally control growth, division and DNA repair and cell death. Cancer: Solving an age-old problem 2012-02-29T18:21:13.613Z “It’s possible that the culture conditions are causing increased on the cells, resulting in cell death.” Cancer Immunity Insights Might Derive from Study of Blind Mole Rats 2012-11-05T23:15:00.120Z Oxygen gets depleted and wastes accumulate, triggering cell death. A Wrinkle in Slime: Cell Deaths Form Biofilm Folds 2012-09-24T20:00:00Z Not only that but cytoplasmic MLA10 alone was enough to cause cell death. How Barley Protects Against Invasion 2012-07-16T14:15:12.883Z Most notably, the mice produced amyloid beta peptides—toxic protein fragments that gum up neurons and lead to cell death—and showed signs of forgetfulness. Alzheimer's Disease Symptoms Reversed in Mice 2012-02-09T19:45:00.207Z Over the next two years, the cell death and destruction spread outward to other cells along the same network. Alzheimer?s Spreads in the Brain Like a Virus, Studies Find 2012-02-02T17:12:23Z Over the next two years, the cell death and destruction spread outward to other cells that are part of the same nerve-cell network. Researchers find clues to how Alzheimer's spreads cell to cell 2012-02-02T05:06:11Z Over the next two years, the cell death and destruction spread outward to other cells that are part of the same nerve cell network. Alzheimer?s Spreads Like a Virus in the Brain, Studies Find 2012-02-01T22:00:34Z As the groups reached a certain size, some cells underwent programmed cell death, providing places for daughter clumps to break from. Evolution: The Rise of Complexity 2012-01-16T21:15:00.253Z Markers of brain cell death include amyloid plaques and tangles, Morris said. Alzheimer’s Gene Carriers May Cut Risk With Exercise, Study Says 2012-01-11T21:24:54Z The current research indicates that microRNA are at the heart of neuron survival, acting to essentially turn off the apoptosis mechanism that leads to cell death. Ten Brain Science Studies from 2011 Worth Talking About 2011-12-27T21:30:10Z A number of scientists suspect that the culprit in this cell death is the mitochondria, energy-producing organelles inside cells that malfunction and cause neurons in those movement-control areas to die or become impaired. Medical: Parkinson's disease culprits lie in, outside cells 2011-12-05T19:43:04Z The body has therefore evolved two major systems to curb the risk of cancer — cell senescence and cell death. In Body?s Shield Against Cancer, a Culprit in Aging May Lurk 2011-11-21T19:46:51Z Selective inhibition of CMA slows tumor growth, boosts tumor cell death, and induces the regression of existing tumors. [Perspectives] Targeting Chaperone-Mediated Autophagy in Cancer 2011-11-16T19:55:15.423Z Once attached, the drug releases a synthetic molecule that triggers a natural process of cell death that kills the fat cells. Drug helps fat monkeys slim down - are people next? 2011-11-10T01:14:21Z Present at the media briefing and offering his support was Miroslav Radman, a Croatia-born scientist at the medical faculty of Paris University V, France, known for his work on DNA repair and bacterial cell death. 'Elixir of Youth' Sparks Clash of Croatian Scientists 2011-11-07T18:41:23Z Multiple mutations in DNA—specifically, abnormalities in the p21 and p53 genes, among other changes—stop the process of apoptosis, or programmed cell death, that normal cells undergo. Did Alternative Medicine Extend or Abbreviate Steve Jobs's Life? 2011-10-27T12:15:00.420Z In cell death, a cell is forced to set off a built-in suicide mechanism. In Body?s Shield Against Cancer, a Culprit in Aging May Lurk 2011-11-21T19:46:51Z The fibers are thought to do so by skewering cells, setting off chemical reactions that lead to inflammation, DNA damage and cell death. Carbon Nanotubes Impale Compulsive Cells 2011-09-20T18:45:05.310Z Chilling donor hearts before a transplant slows the rate of cell death and buys time to get the organ to a recipient, but only a little bit, he said. Study tests use of warm-heart transplants 2011-09-14T15:46:04Z Low levels of beta amyloid in spinal fluid suggest it may be accumulating in the brain, and high tau levels suggest nerve cell death. Special report: With Alzheimer's in the genes, when do you test? 2011-07-20T08:39:01Z Once differentiated into neurons, the cells secreted dopamine and were more sensitive to chemicals that can induce cell death than were dopamine-secreting neurons derived from healthy people. Stem cells: The growing pains of pluripotency 2011-05-18T17:20:32.423Z Plant material in the ocean is broken down by cell death, microbial action and grazing by zooplankton, producing CDOM. The Catlin Arctic Survey: A Melting Ocean 2011-04-20T13:45:00.257Z Arsenic causes harm through oxidative stress on living cells, interfering with normal enzymatic processes and leading to cell death. Q & A: Name Your Poison 2011-04-18T19:23:22Z "Knowing more about what causes and prevents brain cell death in Alzheimer's disease will undoubtedly be important for the development of future Alzheimer's treatments." U.S. team makes key memory cells in lab dish 2011-03-04T06:01:05Z This suggests that the receptors, in the absence of hormone binding, are not “turned off” but rather appear to be producing a signal that is permissive for cell death. Editors' Choice 2011-01-13T19:25:02.660Z All of the binging rats experienced cell death in portions of their brains outside the dentate gyrus, and most of those were not reduced by exercise. Well: Does Exercising Make You Drink More Alcohol? 2011-01-05T05:01:21Z The sleep hormone melatonin, stress and increased cell death are all possible culprits that need to be explored, Gibson said. Jet Lag Makes Hamsters Dumb 2010-11-17T19:33:00Z The drug works by interfering with a process of programed cell death called apoptosis -- basically a form of cell suicide. U.S. invests in drug to protect against radiation 2010-09-17T20:31:00Z Her team found significant changes in the smokers' expression of genes that influence immune response, cell death, cancer and metabolism of foreign particles compared to what was seen among nonsmokers. Medical: Docs find different responses to stop-smoking treatments 2010-09-01T18:34:00Z Another medication, Namenda, works to reduce the excessive amount of the neurotransmitter glutamate produced by Alzheimer's brains; too much glutamate results in cell death. Researchers hope to quell a surge of Alzheimer's cases with new diagnostic tools 2010-08-23T17:31:00Z These results contradict previous studies that show lots of cell death in muscles during atrophy. Muscles Remember Past Glory 2010-08-18T14:54:00Z And they are testing hundreds of new drugs that, they hope, might slow or stop the relentless brain cell death that robs people of their memories and abilities to think and reason. Spinal-Fluid Test Is a Predictor of Alzheimer?s 2010-08-09T20:50:00Z The idea is to attack the disease when there may still be time to stop the worst brain cell death. Drug Trials Test Bold Plan to Slow Alzheimer?s 2010-07-17T01:35:00Z In normal cells, this process of "programmed cell death", or apoptosis, happens automatically, but in the polyps, the process does not work as well. Chemical 'nips cancer in the bud' 2010-03-28T23:17:00Z Local hyperthermia above 43 degrees Centigrade causes cell death, the researchers note in the Journal of Infectious Diseases. Heat treatment found effective for plantar warts 2010-03-19T20:15:00Z In a moist atmosphere, the penetrating power of heat is great, consequently cell death occurs at a lower temperature than in a dry atmosphere. Outlines of dairy bacteriology A concise manual for the use of students in dairying Perhaps some of these other conditions set off waves of cell death independent of amyloid beta. Drug Trials Test Bold Plan to Slow Alzheimer?s 2010-07-17T01:35:00Z |
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