单词 | cDNA |
例句 | The HGH gene was cloned from a cDNA library and inserted into E. coli cells by cloning it into a bacterial vector. Biology for AP Courses 2022-06-09T00:00:00Z The primer tries to connect itself to cDNA from the virus and make a copy. New COVID Spit Tests May Be More Accurate and Easier Than Nasal Swabs 2022-03-28T04:00:00Z The company’s test created cDNA, which is a clone or copy of the DNA, to test for the mutations. NOT REAL NEWS: A look at what didn’t happen this week 2021-07-16T04:00:00Z Finally, to assess the effect of each variant on expression, we tested for a significant difference between the cDNA and gDNA alternate allele proportions with a two-sided t-test. The impact of rare variation on gene expression across tissues : Nature : Nature Research 2017-10-10T04:00:00Z Approximately half of the cDNA product was used for library construction, and indexed libraries were generated using 18 cycles of PCR. Zika virus evolution and spread in the Americas : Nature : Nature Research 2017-05-23T04:00:00Z An EST is a short STS that is identified with cDNA libraries, while SSLPs are obtained from known genetic markers and provide a link between genetic maps and physical maps. Biology for AP Courses 2022-06-09T00:00:00Z As the process is repeated, or “cycled,” any cDNA is amplified through these copies until it can be easily identified and deemed a positive sample. New COVID Spit Tests May Be More Accurate and Easier Than Nasal Swabs 2022-03-28T04:00:00Z The protocol employed cDNA synthesis with random primers followed by gene specific multiplex PCR and is presented in detail in ref. Establishment and cryptic transmission of Zika virus in Brazil and the Americas : Nature : Nature Research 2017-05-23T04:00:00Z Two variants were excluded owing to low cDNA and gDNA total reads counts. The impact of rare variation on gene expression across tissues : Nature : Nature Research 2017-10-10T04:00:00Z RNA samples extracted from whole blood from 175 EVD patients were reverse transcribed to cDNA. Genetic diversity and evolutionary dynamics of Ebola virus in Sierra Leone : Nature : Nature Publishing Group 2015-05-12T04:00:00Z After the cDNA is made, regular PCR can be used to amplify it. Biology for AP Courses 2022-06-09T00:00:00Z The cDNA is available from Addgene, and the flies are available as well! Lighting up the brain with ArcLight 2013-08-12T13:45:03.067Z Without the licensing to BRCA1/2 cDNA, certain cancer research may be restricted to Myriad. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z In the opinion, Thomas wrote that because cDNA is not naturally occurring, it can be patented under federal law. U.S. top court bars patents on human genes unless synthetic 2013-06-14T04:57:01Z “The lab technician unquestionably creates something new when cDNA is made,” Thomas wrote. Supreme Court rejects idea of patenting natural human genes 2013-06-14T04:20:01Z The Supreme Court said cDNA was eligible for patenting because it was not naturally occurring. After DNA Patent Ruling, Availability of Genetic Tests Could Broaden 2013-06-14T01:29:36Z Pharmaceutical companies use cDNA to produce proteins such as insulin and human growth hormone. As top court invalidates some gene patents, biotech has moved on 2013-06-13T23:07:35Z We’ve created fruit flies with cDNA disease genes in order to study how the disease kills neurons, with the eventual goal of finding new therapeutic targets. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z A laboratory technician, he added, "unquestionably creates something new when cDNA is made." U.S. top court bars patents on human genes unless synthetic 2013-06-14T04:57:01Z Although "cDNA retains the naturally occurring exons of DNA … it is distinct from the DNA from which it was derived," the court wrote. U.S. Supreme Court Strikes Down Human Gene Patents 2013-06-13T22:00:00Z Just after this, they write: “cDNA contains only the exons that occur in DNA, omitting the intervening introns.” Supreme Court Gets Decision Right On Gene Patents, Science Wrong 2013-06-13T19:21:00Z Sandra Park, a senior staff attorney for the American Civil Liberties Union, says that this decision will not impact genetic testing since cDNA is not necessary for that process. Supreme Court Rejects Patents on Two Naturally Occurring Genes 2013-06-13T19:15:08.280Z In order to understand the critical distinction between DNA and cDNA, some background is necessary. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z Called cDNA - the "c" stands for "complementary" - it is essentially an edited form of a gene, with extraneous stretches excised. U.S. top court bars patents on human genes unless synthetic 2013-06-14T04:57:01Z "As a result, cDNA is not a 'product of nature' and is patent eligible." U.S. Supreme Court Strikes Down Human Gene Patents 2013-06-13T22:00:00Z In examining the differences between the two, Thomas concluded that cDNA is not naturally occurring. Supreme Court OKs patenting of human DNA if synthetic 2013-06-13T16:48:50Z The court also determined that synthetically created DNA, cDNA, which contains the same information as its natural cousin but omits portions within the DNA segment that do not code for proteins, is patentable. Supreme Court Rejects Patents on Two Naturally Occurring Genes 2013-06-13T19:15:08.280Z But, because physically making the cDNA meant the scientists created something new, the Supreme Court held that cDNA was eligible to be patented. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z The plaintiffs said they were not concerned about the ruling on cDNA because patents relating to that, in their view, have little impact on genetic testing, their focus in the case. U.S. top court bars patents on human genes unless synthetic 2013-06-14T04:57:01Z On the other hand, Thomas wrote, Myriad’s creation of a synthetic form of DNA — called cDNA -- based on its discovery does deserve patent protection. Supreme Court rules human genes may not be patented 2013-06-13T16:11:00Z The ruling means some of Myriad's patents involving cDNA will likely survive, but the parties disagreed on that point. Supreme Court OKs patenting of human DNA if synthetic 2013-06-13T16:48:50Z To represent all U. gibba organs, 2μg of RNA from each sample were pooled. cDNA synthesis was performed as described previously. Architecture and evolution of a minute plant genome 2013-06-05T17:21:05.400Z For example, the edited cDNA sequence, not the longer DNA sequence, is often used to create animal models of diseases. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z Kennedy said that when he first looked at the case, "I thought that maybe the cDNA was kind of an economy-class gene" but then realized that it wasn't; he seemed confused. Can Human Genes Be Patented? 2013-04-17T20:25:00Z “The lab technician creates something new when cDNA is made,” Thomas wrote. Supreme Court rules human genes may not be patented 2013-06-13T16:11:00Z Court of Appeals for the Federal Circuit was wrong to find that isolated human DNA and cDNA were both patent eligible. Supreme Court OKs patenting of human DNA if synthetic 2013-06-13T16:48:50Z A majority appeared inclined to find that cDNA could be patented. Justices wary of wide human gene patent ruling 2013-04-16T00:59:10Z Next, cDNA is critical for developing new diagnostic tests for genetic disorders. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z The heatmaps show the density distribution of barley cDNA loci that are aligned with genes. Aegilops tauschii draft genome sequence reveals a gene repertoire for wheat adaptation 2013-04-03T17:22:05.187Z We strongly support the court's decision that isolated DNA and cDNA are patent-eligible material. U.S. Appeals Court Backs Gene Patents in Myriad Case 2011-07-29T22:27:36Z Thomas wrote that cDNA "does not present the same obstacles to patentability as naturally occurring isolated DNA segments." Supreme Court OKs patenting of human DNA if synthetic 2013-06-13T16:48:50Z If the court were to adopt that approach, which neither the plaintiffs nor Myriad accept, some of Myriad's patents, concerning synthetic molecules called cDNA, could survive, although the parties disagree on that point as well. Justices wary of wide human gene patent ruling 2013-04-16T00:59:10Z But, said the Court, cDNA, a man-made copy of the genetic messenger in cells, is patentable. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z The heatmaps show the density distribution of barley cDNA loci that are aligned with genes. Aegilops tauschii draft genome sequence reveals a gene repertoire for wheat adaptation 2013-04-03T17:22:05.187Z The most effective weapon for us to find such genes—veritable needles in the haystack of transcribed genes—was an expressed sequence tag database, a mouse cDNA library developed and made public by RIKEN. [Essay] Genome-Sequencing Anniversary: Of Mice and Humans 2011-02-17T19:26:25.353Z A laboratory technician, he wrote, "unquestionably creates something new when cDNA is made." Supreme Court OKs patenting of human DNA if synthetic 2013-06-13T16:48:50Z This spreadsheet provides a general description of each cDNA data set generated for this project, as well as an internal experiment ID, flow cell ID, submission date and a Short Read Archive accession number. Comparative and demographic analysis of orang-utan genomes 2011-01-26T18:22:58.603Z Myriad did not create the sequence of the BRCA1/2 cDNA; the sequence is a complementary copy of patients’ mRNA. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z “Chemical synthesis of poliovirus cDNA: generation of infectious virus in the absence of natural template.” Baby Steps to New Life-Forms 2010-05-28T01:23:00Z They claim cDNA is something "new"which doesn't occur in nature, but the body is constantly doing essentially the same as makers of cDNA as mRNA omits the "junk" introns, and constructs proteins. 2010-02-04T15:15:00Z Why do Myriad’s patent rights to cDNA matter? New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z Researchers are quite concerned about the implications of cDNA patents. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z But unpublished cDNA in ongoing research is vulnerable. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z The rationale for allowing cDNA to be patented is that it is synthetic. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z Just like pre-RNA is a complementary copy of the DNA template, the cDNA is a complementary copy of the mRNA template. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z The naturally occurring gene contains exons, introns, and other genetic material; the cDNA contains only exons. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z Vague language in the cDNA patent decision stirs additional concerns. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z New Supreme Court Decision Rules That cDNA Is Patentable—What It Means for Research and Genetic Testing In a unanimous decision last month, the Supreme Court ruled that naturally occurring genes are not patentable. New Supreme Court Decision Rules That cDNA Is Patentable What It Means for Research and Genetic Testing 2013-07-09T15:45:05.410Z |
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