英语词汇“CD4 T cell”造句的方法、技巧、例句及翻译-英语例句辞典

The two types of activated T cell then sequentially or simultaneously recognize antigens on DC1s, and CD4 T cells provide effective ‘help’ to CD8 T cells3,4. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z

Many immunologists suspect the Ad5 led to an especially large increase in CD4 T cells, the favorite target of HIV. Operation Warp Speed selects billionaire scientist’s COVID-19 vaccine for monkey tests 2020-06-01T04:00:00Z

Consistent with these findings, previous work7 indicates that macrophage activation triggered by IFN-γ from CD4 T cells leads to the inhibition of tumour growth. Teamwork by different T-cell types boosts tumour destruction by immunotherapy 2019-10-22T04:00:00Z

In addition to putting genes for the CARs into the killer T cells—which are distinguished by the surface protein CD8—the researchers also modified CD4 T cells. Can an immune strategy used to treat cancer also wipe out HIV infections? 2019-08-07T04:00:00Z

They are called CD4 T cells and CD8 T cells, respectively. Regulatory T cells subdue an autoimmune disease 2019-08-06T04:00:00Z

For example, CD4 T cells secrete molecules that directly support CD8 T cells. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z

In NOD mice, a class II MHC molecule called I-Ag7 presents B:12–20 to CD4 T cells and activates them. Peptide secretion triggers diabetes 2018-07-17T04:00:00Z

Fang, D. & Zhu, J. Dynamic balance between master transcription factors determines the fates and functions of CD4 T cell and innate lymphoid cell subsets. Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism 2018-01-21T05:00:00Z

Left, CD4 T cells were purified from patient MCL030 after autologous tumour vaccination. Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens : Nature : Nature Research 2017-03-21T04:00:00Z

These cells suppress the proliferation of CD4 T cells in a process that involves the recognition of antigens presented by MHC proteins. Regulatory T cells subdue an autoimmune disease 2019-08-06T04:00:00Z

CD4 T cells also induce DC1s to express molecules that further boost the activation of CD8 T cells, a process referred to as licensing. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z

The authors sought to investigate how and where the diabetes-causing CD4 T cells are activated. Peptide secretion triggers diabetes 2018-07-17T04:00:00Z

The depletion of quiescent CD4 T cells from lymphoid organs is a major event contributing to the development of AIDS. [Report] IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV 2014-01-23T19:26:36.416Z

The authors found that the CD4 T cells in question recognized MOG-derived peptide fragments and so were primed to specifically attack myelin-coated nerve cells and cause disease. Regulatory T cells subdue an autoimmune disease 2019-08-06T04:00:00Z

This indicates that CD4 T cells are needed for both types of response in this system. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z

However, when mice received a drug that blocks insulin binding and uptake, this did not block insulin recognition by CD4 T cells in lymph nodes. Peptide secretion triggers diabetes 2018-07-17T04:00:00Z

These findings provide insights into a key host pathway that plays a central role in CD4 T cell depletion during disease progression to AIDS. [Report] IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV 2014-01-23T19:26:36.416Z

But this only happens to a small portion of CD4 T cells. Twin U.S. studies unlock mystery of how HIV causes AIDS 2013-12-19T20:02:55Z

We further demonstrate that CD4 T cells are stable in inflammatory conditions not only in vitro but also in vivo in a model of xenogeneic graft-versus-host disease. [Research Articles] CD4+ T Cells from IPEX Patients Convert into Functional and Stable Regulatory T Cells by FOXP3 Gene Transfer 2013-12-11T21:25:08.624Z

To track the activation of CD4 T cells, the authors took CD4 T cells engineered to express a TCR that recognizes the ovalbumin antigen, and transferred them into tumour-bearing mice. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z

Regulatory CD4 T cells include subsets that are distinguished on the basis of their expression of the transcription factor, Foxp3. Reciprocal interactions of the intestinal microbiota and immune system 2012-09-13T11:20:55.227Z

But it is still not clear, says van der Burg, whether the response comes from CD8 T cells, which destroy HPV-infected cells, or by CD4 T cells, which help other white blood cells fight infection. Pathology: Three questions 2012-08-29T17:51:27.637Z

Robust CD8 and CD4 T cell priming and boosting to all vaccine antigens were observed in the absence of autoimmunity. [Research Articles] CD25 Blockade Depletes and Selectively Reprograms Regulatory T Cells in Concert with Immunotherapy in Cancer Patients 2012-05-16T18:55:13.183Z

IPEX-derived CD4 T cells mirrored T cells from healthy donors in terms of cellular markers, anergic phenotype, cytokine production, and suppressive function. [Research Articles] CD4+ T Cells from IPEX Patients Convert into Functional and Stable Regulatory T Cells by FOXP3 Gene Transfer 2013-12-11T21:25:08.624Z

How do DC1s support the activation of both CD8 and CD4 T cells? A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z

The diversity of ILC subsets seems to parallel that of CD4 T cells, with which they share many functional features. Reciprocal interactions of the intestinal microbiota and immune system 2012-09-13T11:20:55.227Z

The researchers obtained immune cells called CD4 T cells—the prime targets of HIV—from all the volunteers and subjected these cells to lab tests. Anticancer Protein Might Combat HIV 2010-10-25T16:14:00Z

In the new study, molecular biologist Janice Clements of Johns Hopkins University in Baltimore and her colleagues infected human CD4 T cells with HIV in lab dishes, then added minocycline to some of these batches. Existing Antibiotic Might Help Keep Wraps On AIDS Virus 2010-03-26T15:27:00Z

Unlike previous reports, the work shows that the initial activation of CD4 T cells by tumour antigens is mediated by DC1s. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z

Using genetic manipulation, Ferris et al. show that expression of the receptor protein CD40 in DC1s is essential for the activation of CD4 T cells, effective priming of CD8 T cells and tumour rejection. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z

Finally, at steady state, antigen presentation by intestinal dendritic cells favours the development of regulatory CD4 T cells, which suppress the development of pro-inflammatory innate and effector T-cell responses to avert excessive inflammation. Reciprocal interactions of the intestinal microbiota and immune system 2012-09-13T11:20:55.227Z

The evidence from the genetic removal of CD40 in DC1s indicates the protein’s role in enabling CD4 T cells to aid the responses of CD8 T cells. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z

However, the authors did not analyse the details of how CD4 T cells influence and license DC1s to activate CD8 T cells. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z

In particular, it would be interesting to study whether interactions between DC1s and CD4 T cells modulate the expression of key immune-cell regulators, such as checkpoint proteins or soluble molecules called cytokines. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z

This study provides compelling genetic evidence that DC1s support CD4 T cells in providing help for tumour-specific immune responses by CD8 T cells. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z

Owing to their defined antigenic specificity and durable memory, effector CD4 T cells are a liability when inappropriately directed against self-antigens or, in the case of the microbiota, the 'extended' self. Reciprocal interactions of the intestinal microbiota and immune system 2012-09-13T11:20:55.227Z

单词	CD4 T cell
例句	CD4 T cell The two types of activated T cell then sequentially or simultaneously recognize antigens on DC1s, and CD4 T cells provide effective ‘help’ to CD8 T cells3,4. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z Many immunologists suspect the Ad5 led to an especially large increase in CD4 T cells, the favorite target of HIV. Operation Warp Speed selects billionaire scientist’s COVID-19 vaccine for monkey tests 2020-06-01T04:00:00Z Consistent with these findings, previous work7 indicates that macrophage activation triggered by IFN-γ from CD4 T cells leads to the inhibition of tumour growth. Teamwork by different T-cell types boosts tumour destruction by immunotherapy 2019-10-22T04:00:00Z In addition to putting genes for the CARs into the killer T cells—which are distinguished by the surface protein CD8—the researchers also modified CD4 T cells. Can an immune strategy used to treat cancer also wipe out HIV infections? 2019-08-07T04:00:00Z They are called CD4 T cells and CD8 T cells, respectively. Regulatory T cells subdue an autoimmune disease 2019-08-06T04:00:00Z For example, CD4 T cells secrete molecules that directly support CD8 T cells. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z In NOD mice, a class II MHC molecule called I-Ag7 presents B:12–20 to CD4 T cells and activates them. Peptide secretion triggers diabetes 2018-07-17T04:00:00Z Fang, D. & Zhu, J. Dynamic balance between master transcription factors determines the fates and functions of CD4 T cell and innate lymphoid cell subsets. Innate and adaptive lymphocytes sequentially shape the gut microbiota and lipid metabolism 2018-01-21T05:00:00Z Left, CD4 T cells were purified from patient MCL030 after autologous tumour vaccination. Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens : Nature : Nature Research 2017-03-21T04:00:00Z These cells suppress the proliferation of CD4 T cells in a process that involves the recognition of antigens presented by MHC proteins. Regulatory T cells subdue an autoimmune disease 2019-08-06T04:00:00Z CD4 T cells also induce DC1s to express molecules that further boost the activation of CD8 T cells, a process referred to as licensing. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z The authors sought to investigate how and where the diabetes-causing CD4 T cells are activated. Peptide secretion triggers diabetes 2018-07-17T04:00:00Z The depletion of quiescent CD4 T cells from lymphoid organs is a major event contributing to the development of AIDS. [Report] IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV 2014-01-23T19:26:36.416Z Left, CD4 T cells were purified from patient MCL030 after autologous tumour vaccination. Antigen presentation profiling reveals recognition of lymphoma immunoglobulin neoantigens : Nature : Nature Research 2017-03-21T04:00:00Z The authors found that the CD4 T cells in question recognized MOG-derived peptide fragments and so were primed to specifically attack myelin-coated nerve cells and cause disease. Regulatory T cells subdue an autoimmune disease 2019-08-06T04:00:00Z This indicates that CD4 T cells are needed for both types of response in this system. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z However, when mice received a drug that blocks insulin binding and uptake, this did not block insulin recognition by CD4 T cells in lymph nodes. Peptide secretion triggers diabetes 2018-07-17T04:00:00Z These findings provide insights into a key host pathway that plays a central role in CD4 T cell depletion during disease progression to AIDS. [Report] IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV 2014-01-23T19:26:36.416Z But this only happens to a small portion of CD4 T cells. Twin U.S. studies unlock mystery of how HIV causes AIDS 2013-12-19T20:02:55Z We further demonstrate that CD4 T cells are stable in inflammatory conditions not only in vitro but also in vivo in a model of xenogeneic graft-versus-host disease. [Research Articles] CD4+ T Cells from IPEX Patients Convert into Functional and Stable Regulatory T Cells by FOXP3 Gene Transfer 2013-12-11T21:25:08.624Z To track the activation of CD4 T cells, the authors took CD4 T cells engineered to express a TCR that recognizes the ovalbumin antigen, and transferred them into tumour-bearing mice. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z Regulatory CD4 T cells include subsets that are distinguished on the basis of their expression of the transcription factor, Foxp3. Reciprocal interactions of the intestinal microbiota and immune system 2012-09-13T11:20:55.227Z But it is still not clear, says van der Burg, whether the response comes from CD8 T cells, which destroy HPV-infected cells, or by CD4 T cells, which help other white blood cells fight infection. Pathology: Three questions 2012-08-29T17:51:27.637Z Robust CD8 and CD4 T cell priming and boosting to all vaccine antigens were observed in the absence of autoimmunity. [Research Articles] CD25 Blockade Depletes and Selectively Reprograms Regulatory T Cells in Concert with Immunotherapy in Cancer Patients 2012-05-16T18:55:13.183Z IPEX-derived CD4 T cells mirrored T cells from healthy donors in terms of cellular markers, anergic phenotype, cytokine production, and suppressive function. [Research Articles] CD4+ T Cells from IPEX Patients Convert into Functional and Stable Regulatory T Cells by FOXP3 Gene Transfer 2013-12-11T21:25:08.624Z How do DC1s support the activation of both CD8 and CD4 T cells? A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z The diversity of ILC subsets seems to parallel that of CD4 T cells, with which they share many functional features. Reciprocal interactions of the intestinal microbiota and immune system 2012-09-13T11:20:55.227Z The researchers obtained immune cells called CD4 T cells—the prime targets of HIV—from all the volunteers and subjected these cells to lab tests. Anticancer Protein Might Combat HIV 2010-10-25T16:14:00Z In the new study, molecular biologist Janice Clements of Johns Hopkins University in Baltimore and her colleagues infected human CD4 T cells with HIV in lab dishes, then added minocycline to some of these batches. Existing Antibiotic Might Help Keep Wraps On AIDS Virus 2010-03-26T15:27:00Z Unlike previous reports, the work shows that the initial activation of CD4 T cells by tumour antigens is mediated by DC1s. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z Using genetic manipulation, Ferris et al. show that expression of the receptor protein CD40 in DC1s is essential for the activation of CD4 T cells, effective priming of CD8 T cells and tumour rejection. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z Finally, at steady state, antigen presentation by intestinal dendritic cells favours the development of regulatory CD4 T cells, which suppress the development of pro-inflammatory innate and effector T-cell responses to avert excessive inflammation. Reciprocal interactions of the intestinal microbiota and immune system 2012-09-13T11:20:55.227Z The evidence from the genetic removal of CD40 in DC1s indicates the protein’s role in enabling CD4 T cells to aid the responses of CD8 T cells. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z However, the authors did not analyse the details of how CD4 T cells influence and license DC1s to activate CD8 T cells. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z In particular, it would be interesting to study whether interactions between DC1s and CD4 T cells modulate the expression of key immune-cell regulators, such as checkpoint proteins or soluble molecules called cytokines. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z This study provides compelling genetic evidence that DC1s support CD4 T cells in providing help for tumour-specific immune responses by CD8 T cells. A dendritic cell multitasks to tackle cancer 2020-08-11T04:00:00Z Owing to their defined antigenic specificity and durable memory, effector CD4 T cells are a liability when inappropriately directed against self-antigens or, in the case of the microbiota, the 'extended' self. Reciprocal interactions of the intestinal microbiota and immune system 2012-09-13T11:20:55.227Z
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