| 单词 | adrenergic |
| 例句 | The terms cholinergic and adrenergic refer not only to the signaling molecule that is released but also to the class of receptors that each binds. Anatomy and Physiology 2013-06-19T00:00:00Z I struggled for 10 minutes with a 10-letter puzzle only to give up and be told the word was... adrenergic. Done your Wordle for the day? Try out these spoofs instead 2022-01-11T05:00:00Z In this case, neurons increased in number in the vicinity of the tumour, and these cells were reprogrammed as adrenergic neurons that express the molecule noradrenaline. Loss of p53 protein strikes a nerve to aid tumour growth 2020-02-11T05:00:00Z Another mystery is which types of adrenergic receptor are crucial for the effects of catecholamines on cytokine levels in humans. Adrenaline fuels a cytokine storm during immunotherapy 2018-12-11T05:00:00Z This replacement marrow was deficient in a specific molecule called adrenergic receptor beta, which made the bone marrow less responsive to the neural messages from the brain. Tiny gut organisms may influence food cravings and what our bodies do with fatLooking at microbiota for ways to keep weight down — and fight depression 2017-08-11T04:00:00Z Norepinephrine and epinephrine belong to the adrenergic neurotransmitter system. Anatomy and Physiology 2013-06-19T00:00:00Z They’ve identified a protein called β3 adrenergic receptor that, when activated, encourages brown fat cells to burn off more fat and produce more heat. Could turning out the lights help you burn fat? 2015-05-11T04:00:00Z Interestingly, previous epidemiological analysis9 revealed that the use of the drug carvedilol, which blocks adrenergic signalling and is prescribed for conditions such as high blood pressure, is associated with a reduced risk of cancer onset. Loss of p53 protein strikes a nerve to aid tumour growth 2020-02-11T05:00:00Z What breakthrough allowed you to determine the structure of the β2 adrenergic receptor? Q&A: Brian Kobilka : Nature : Nature Publishing Group 2014-10-14T04:00:00Z One receptor involved in this pathway is known — the β3 adrenergic receptor. Cell physiology: The changing colour of fat 2014-04-16T17:21:54.590Z An additional aspect of the adrenergic system is that there is a second signaling molecule called epinephrine. Anatomy and Physiology 2013-06-19T00:00:00Z Kobilka’s work led to the cloning of the gene for the adrenergic receptor, and eventually the genes for many others. Two Americans get chemistry Nobel for elucidating cellular receptors 2012-10-11T01:19:26Z The authors’ findings are of particular interest because these insights might offer a way to combat the tumour-driven formation of adrenergic neurons and to counteract their tumour-promoting effects. Loss of p53 protein strikes a nerve to aid tumour growth 2020-02-11T05:00:00Z Afterwards I recruited two very talented postdocs to join the effort and they succeeded in determining structures of the β2 adrenergic receptor in 2007 with the help of Stanford colleagues and collaborators from other universities. Q&A: Brian Kobilka : Nature : Nature Publishing Group 2014-10-14T04:00:00Z They all work the same way, by acting on a specific receptor in the lung muscles called the "beta 2 adrenergic receptor." Discovery could lead to new asthma treatments 2010-10-25T16:48:00Z The term adrenergic should remind you of the word adrenaline, which is associated with the fight-or-flight response described at the beginning of the chapter. Anatomy and Physiology 2013-06-19T00:00:00Z The first receptor Lefkowitz identified and isolated was the “beta-2 adrenergic receptor,” which is the one that responds to adrenaline and is the target of asthma drugs such as albuterol. Two Americans get chemistry Nobel for elucidating cellular receptors 2012-10-11T01:19:26Z Also, to increase the effectiveness of adrenergic chemicals released from the fibers, some of these drugs may block the removal or reuptake of the neurotransmitter from the synapse. Anatomy and Physiology 2013-06-19T00:00:00Z Phenylephrine is known as an α1-adrenergic agonist, meaning that it binds to a specific adrenergic receptor, stimulating a response. Anatomy and Physiology 2013-06-19T00:00:00Z In this role, phenylephrine will bind to the adrenergic receptors in bronchioles of the lungs and cause them to dilate. Anatomy and Physiology 2013-06-19T00:00:00Z Having understood the cholinergic and adrenergic systems, their role in the autonomic system is relatively simple to understand. Anatomy and Physiology 2013-06-19T00:00:00Z Figure 15.14 Mydriasis The sympathetic system causes pupillary dilation when norepinephrine binds to an adrenergic receptor in the radial fibers of the iris smooth muscle. Anatomy and Physiology 2013-06-19T00:00:00Z Other drugs that enhance adrenergic function are not associated with therapeutic uses, but affect the functions of the sympathetic system in a similar fashion. Anatomy and Physiology 2013-06-19T00:00:00Z Adenosine will suppress adrenergic activity, specifically the release of norepinephrine at synapses, so caffeine indirectly increases adrenergic activity. Anatomy and Physiology 2013-06-19T00:00:00Z They primarily work as an antagonist to the adrenergic receptors. Anatomy and Physiology 2013-06-19T00:00:00Z A drug that enhances adrenergic function is known as a sympathomimetic drug, whereas a drug that interrupts adrenergic function is a sympatholytic drug. Anatomy and Physiology 2013-06-19T00:00:00Z It also impacts the beta adrenergic response similar to epinephrine and NE described above. Anatomy and Physiology 2013-06-19T00:00:00Z If norepinephrine is released, it will bind to the adrenergic receptors present on the target cell, and if ACh is released, it will bind to the muscarinic receptors on the target cell. Anatomy and Physiology 2013-06-19T00:00:00Z If norepinephrine is released onto those cells, it binds to an adrenergic receptor that causes the cells to depolarize faster, and the heart rate increases. Anatomy and Physiology 2013-06-19T00:00:00Z These tissues have adrenergic receptors that respond to the release of norepinephrine from postganglionic sympathetic fibers by constricting and increasing blood pressure. Anatomy and Physiology 2013-06-19T00:00:00Z These drugs either bind to particular adrenergic receptors and mimic norepinephrine at the synapses between sympathetic postganglionic fibers and their targets, or they increase the production and release of norepinephrine from postganglionic fibers. Anatomy and Physiology 2013-06-19T00:00:00Z Drugs such as phenylephrine bind to the adrenergic receptors and stimulate target organs just as sympathetic activity would. Anatomy and Physiology 2013-06-19T00:00:00Z Other drugs are sympatholytic because they block adrenergic activity and cancel the sympathetic influence on the target organ. Anatomy and Physiology 2013-06-19T00:00:00Z |
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