| 单词 | xenotransplantation |
| 例句 | “His heart is doing everything on its own,” said Dr. Muhammad Mohiuddin, the Maryland team’s cardiac xenotransplantation chief. Pig heart transplant recipient reaches 1-month mark, pushing through physical therapy 2023-10-20T04:00:00Z Some people criticize xenotransplantation as a distraction from addressing the problems with the existing transplant system. No One Should Die Waiting for an Organ Transplant. These Doctors Want to Ensure That Doesn’t Happen 2023-10-19T04:00:00Z More than 100,000 people are waiting for an organ transplant—most of them for kidneys—so researchers have long been exploring xenotransplantation: transplanting other species’ organs into humans. Milestone Pig-to-Human Heart Transplant May Pave the Way for Broader Trial 2023-10-18T04:00:00Z The new data could help convince regulators that xenotransplantation is ready for clinical trials in humans. Monkeys with Transplanted Pig Kidneys Live for Up to Two Years or More 2023-10-11T04:00:00Z “It’s just an amazing feeling to see this pig heart work in a human,” said Dr. Muhammad Mohiuddin, the Maryland team’s xenotransplantation expert. Surgeons perform second pig heart transplant, trying to save a dying man 2023-09-22T04:00:00Z So-called xenotransplantation attempts have failed for decades - the human immune system immediately destroyed foreign animal tissue. Pig kidney works a record 2 months in donated body, raising hope for animal-human transplants 2023-09-15T04:00:00Z Now is the time for something bigger, he argues, and xenotransplantation is the answer. No One Should Die Waiting for an Organ Transplant. These Doctors Want to Ensure That Doesn’t Happen 2023-10-19T04:00:00Z The FDA will be closely watching the progress of Faucette’s recovery, which could inform the agency’s decision to approve clinical trials of xenotransplantation. Milestone Pig-to-Human Heart Transplant May Pave the Way for Broader Trial 2023-10-18T04:00:00Z In the late 1990s concern over these viruses infecting transplant recipients prompted calls for a moratorium on xenotransplantation, but ultimately the FDA allowed research to resume. Monkeys with Transplanted Pig Kidneys Live for Up to Two Years or More 2023-10-11T04:00:00Z So-called xenotransplantation attempts have failed for decades — the human immune system immediately destroyed foreign animal tissue. Pig kidney works a record 2 months in donated body, raising hope for animal-human transplants 2023-09-14T04:00:00Z After decades of failed attempts, now pigs genetically modified so their organs are more humanlike are renewing interest in so-called xenotransplantation. How a family’s choice to donate a body for pig kidney research could help change transplants 2023-08-19T04:00:00Z Despite these far-fetched ambitions, Rothblatt has funded a wealth of well-grounded research for decades, and her company United Therapeutics has propelled much of the recent progress in xenotransplantation. No One Should Die Waiting for an Organ Transplant. These Doctors Want to Ensure That Doesn’t Happen 2023-10-19T04:00:00Z Attempts at animal-to-human transplants, or xenotransplantation, have failed for decades as people’s immune systems attacked the foreign tissue. Pig kidney works in a donated body for over a month, a step toward animal-human transplants 2023-08-16T04:00:00Z But bridging millions of years of evolutionary divergence between two species is a tall order, so for decades organ xenotransplantation was largely impractical. Monkeys with Transplanted Pig Kidneys Live for Up to Two Years or More 2023-10-11T04:00:00Z It’s the latest in a string of developments renewing hope for animal-to-human transplants, or xenotransplantation, after decades of failure as people’s immune systems attacked the foreign tissue. Pig kidney works in a donated body for over a month, a step toward animal-human transplants 2023-08-16T04:00:00Z “This is probably more of the near future than xenotransplantation,” or directly implanting animal organs into people. Making pig livers humanlike in quest to ease organ shortage 2022-12-27T05:00:00Z “There was sort of a moratorium on any further xenotransplantation until we were able to develop things further with the advent of some new technologies,” Montgomery says. No One Should Die Waiting for an Organ Transplant. These Doctors Want to Ensure That Doesn’t Happen 2023-10-19T04:00:00Z But he said the research educates the public about xenotransplantation so “people will not be shocked” when it’s time to try again in the living. Pig kidney works in a donated body for over a month, a step toward animal-human transplants 2023-08-16T04:00:00Z A new study that was published on Wednesday in Nature demonstrates a key metric of xenotransplantation: the long-term survival of organ recipients. Monkeys with Transplanted Pig Kidneys Live for Up to Two Years or More 2023-10-11T04:00:00Z Animal-to-human transplants, what scientists call xenotransplantation, have been tried for decades without success, as people’s immune systems almost instantly attacked the foreign tissue. Pig organ transplants inch closer with testing in the dead 2022-07-12T04:00:00Z The FDA is considering whether to allow additional xenotransplantation experiments using kidneys or hearts from gene-edited pigs. Making pig livers humanlike in quest to ease organ shortage 2022-12-27T05:00:00Z Locke, director of UAB's Comprehensive Transplant Institute, says she got involved in xenotransplantation to help translate the work of basic scientists into a life-extending therapy. No One Should Die Waiting for an Organ Transplant. These Doctors Want to Ensure That Doesn’t Happen 2023-10-19T04:00:00Z It also dedicated an operating room to xenotransplantation — that room won’t be used for any other surgical procedures. Genetically engineered pig hearts transplanted into dead people 2022-07-12T04:00:00Z Other factors besides gene edits can also influence xenotransplantation outcomes. Monkeys with Transplanted Pig Kidneys Live for Up to Two Years or More 2023-10-11T04:00:00Z David Bennett survived for two months, evidence that xenotransplantation was at least possible. Pig organ transplants inch closer with testing in the dead 2022-07-12T04:00:00Z Stripping away the pig cells removes some of the risks of xenotransplantation, such as lurking animal viruses or hyper-rejection, Ross said. Making pig livers humanlike in quest to ease organ shortage 2022-12-27T05:00:00Z But if he died because of the virus — and not because his body rejected the organ — groups working on xenotransplantation likely won’t have to rethink their overall strategy. A pig virus may have contributed to the death of first pig heart transplant patient 2022-05-06T04:00:00Z There’s still a lot to learn about xenotransplantation and a lot to figure out about the ethical implications of animal-to-human procedures. Genetically engineered pig hearts transplanted into dead people 2022-07-12T04:00:00Z A goal of xenotransplantation is to one day genetically engineer away the need for such medication, however. Monkeys with Transplanted Pig Kidneys Live for Up to Two Years or More 2023-10-11T04:00:00Z And she has taken positions on issues such as xenotransplantation — the interchange of organs between species, including humans — considered audacious not long ago, though no longer. The Battery That Flies 2022-04-16T04:00:00Z Dr Locke describes the moment one of the kidneys started making urine as "remarkable" and feels xenotransplantation can "really change people's lives, and to be blunt, save their lives". Xenotransplantation: Are pigs the future of organ transplants? 2022-03-12T05:00:00Z David Bennett Sr, who had severe heart disease, received a genetically modified pig heart in early January of this year — a major milestone in animal-to-human transplants, or xenotransplantation. A pig virus may have contributed to the death of first pig heart transplant patient 2022-05-06T04:00:00Z The process, called xenotransplantation, offers new hope for tens of thousands of patients with ailing kidneys, hearts and other organs, as there is an acute shortage of donated organs. Patient in Groundbreaking Heart Transplant Dies 2022-03-09T05:00:00Z For now, it’s still too early to tell which research group has the best approach to xenotransplantation, she says. Monkeys with Transplanted Pig Kidneys Live for Up to Two Years or More 2023-10-11T04:00:00Z Bennett’s death is a setback for the accelerating field of xenotransplantation — the process of implanting organs from one species into another. Patient who received a genetically modified pig’s heart has died, hospital says 2022-03-09T05:00:00Z The cause, and therefore the implications for xenotransplantation, is still uncertain. Xenotransplantation: Are pigs the future of organ transplants? 2022-03-12T05:00:00Z Although it’s still too early to say if organ rejection played a role in Bennett’s death, researchers involved in xenotransplantation procedures have stressed that early, positive outcomes don’t necessarily mean long-term success. Patient who received pig heart transplant dies 2022-03-09T05:00:00Z Prior attempts at such transplants — or xenotransplantation — have failed largely because patients’ bodies rapidly rejected the animal organ. US man who got 1st pig heart transplant dies after 2 months 2022-03-09T05:00:00Z He is doing well and has not rejected the animal’s organ, said Dr. Muhammad Mohiuddin, the scientific director of the cardiac xenotransplantation program at the University of Maryland School of Medicine. Kidneys From a Genetically Altered Pig Are Implanted in a Brain-Dead Patient 2022-01-20T05:00:00Z Some scientists, particularly in the field of public health, believe the huge investments in xenotransplantation are misplaced. Patient who received a genetically modified pig’s heart has died, hospital says 2022-03-09T05:00:00Z He said if the issue was frailty, then xenotransplantation "could be successful in the future" but if it came down to anatomy then it could "be potentially a show-stopper". Xenotransplantation: Are pigs the future of organ transplants? 2022-03-12T05:00:00Z All three surgeries reflect advances in the accelerating field of xenotransplantation — the process of implanting organs from one species into another. Researchers implant genetically altered pig kidneys into a brain-dead man 2022-01-20T05:00:00Z Bennett survived significantly longer with the gene-edited pig heart than one of the last milestones in xenotransplantation — when Baby Fae, a dying California infant, lived 21 days with a baboon’s heart in 1984. US man who got 1st pig heart transplant dies after 2 months 2022-03-09T05:00:00Z Dr. Robert Montgomery, the director of the NYU Langone Transplant Institute, said he welcomed the opportunity to learn more about xenotransplantation through work done at other centers. Kidneys From a Genetically Altered Pig Are Implanted in a Brain-Dead Patient 2022-01-20T05:00:00Z Before modified pig organs can be offered widely to people through xenotransplantation, the procedure’s safety and efficacy will have to be tested in clinical trials. Patient who received a genetically modified pig’s heart has died, hospital says 2022-03-09T05:00:00Z This operation was just one of a series of medical breakthroughs that have renewed interest in the field of xenotransplantation. Xenotransplantation: Are pigs the future of organ transplants? 2022-03-12T05:00:00Z For patients receiving a nonhuman organ, a procedure called a xenotransplantation, that risk is multiplied. Pig Kidneys Transplanted to Human in Milestone Experiment 2022-01-20T05:00:00Z Making such procedures — called xenotransplantation — a reality would save untold lives. The ethics of a second chance: Pig heart transplant recipient stabbed a man seven times years ago 2022-01-13T05:00:00Z The 7 January surgery was a milestone for research on transplants between species, known as xenotransplantation. Here’s how scientists pulled off the first pig-to-human heart transplant 2022-01-11T05:00:00Z Doctors have been trying to use animal organs for what is known as xenotransplantation for decades, with mixed success. Three ethical issues around pig heart transplants 2022-01-11T05:00:00Z Past attempts at such transplants — or xenotransplantation — have failed, largely because patients’ bodies rapidly rejected the animal organ. In medical first, patient receives genetically altered pig heart 2022-01-10T05:00:00Z There is still a lot of work to do before xenotransplantation becomes routine. Pig Kidneys Transplanted to Human in Milestone Experiment 2022-01-20T05:00:00Z The possibility of using animal organs for so-called xenotransplantation to meet the demand has long been considered, and using pig heart valves is already common. Man gets genetically-modified pig heart in world-first transplant 2022-01-10T05:00:00Z As xenotransplantation scales up to treat more people, the need for consistency might also limit the number of added human genes, Tector notes. Here’s how scientists pulled off the first pig-to-human heart transplant 2022-01-11T05:00:00Z But prior attempts at such transplants — or xenotransplantation — have failed, largely because patients’ bodies rapidly rejected the animal organ. In 1st, US surgeons transplant pig heart into human patient 2022-01-10T05:00:00Z Researchers such as University of Miami xenotransplantation scientist Christopher Burlak await the day when larger organ transplants from pigs—kidneys, livers, or hearts—help saves lives. Skin, nerve transplants from genetically modified pigs could help humans, but organs are a way off 2021-10-31T04:00:00Z “For the first time ever, I feel like I will see xenotransplantation in my career,” Segev says. Pig Kidneys Transplanted to Human in Milestone Experiment 2022-01-20T05:00:00Z But the procedure was still a landmark step in efforts to perform animal-to-human transplants, called xenotransplantation. Scientists took the first steps toward pig-to-human kidney transplants 2021-10-20T04:00:00Z The dream of animal-to-human transplants — or xenotransplantation — goes back to the 17th century with stumbling attempts to use animal blood for transfusions. Pig-to-human transplants come a step closer with new test 2021-10-19T04:00:00Z Still, Klassen cautioned that it’s only a first tentative step into exploring whether this time around, xenotransplantation might finally work. In 1st, US surgeons transplant pig heart into human patient 2022-01-10T05:00:00Z Since 1993, the council has commissioned and published nearly 30 specialist reports on controversial biomedical issues, ranging from genetic screening to xenotransplantation. Ethical research — the long and bumpy road from shirked to shared 2019-10-28T04:00:00Z “If the result of xenotransplantation is satisfactory with porcine kidneys to humans, then it is likely that hearts would be used with good effects in humans within a few years,” the 87-year-old said. Pig to human heart transplants 'possible within three years' 2019-08-19T04:00:00Z When Lai returned to China, he wanted to continue the xenotransplantation work he had begun in Prather’s lab but couldn’t get funding. China’s CRISPR push in animals promises better meat, novel therapies, and pig organs for people 2019-07-31T04:00:00Z “This is an important step forward in realizing the promise of xenotransplantation, which will save thousands of lives each year in the not-too-distant future,” said United Therapeutics CEO Martine Rothblatt in a statement. Pig-to-human transplants come a step closer with new test 2021-10-19T04:00:00Z The Food and Drug Administration, which oversees xenotransplantation experiments, allowed the surgery under what’s called a “compassionate use” emergency authorization, available when a patient with a life-threatening condition has no other options. In 1st, US surgeons transplant pig heart into human patient 2022-01-10T05:00:00Z Because of the slow pace of chimera research, even some of its proponents predict that xenotransplantation—the use of nonhuman tissue, such as modified pig organs, for transplants—will beat their approach to the clinic. Embryo experiments take ‘baby steps’ toward growing human organs in livestock 2019-06-26T04:00:00Z “Nobody would dare speak” about running clinical trials for xenotransplantation, says Leo Bühler, president of the International Xenotransplantation Association. Do animals hold the key to the global organ shortage? 2019-04-03T04:00:00Z The study is invigorating xenotransplantation researchers who, after decades of sometimes dismal attempts, say human trials are finally in sight. Pig Hearts Successfully Transplanted into Baboons for First Time 2018-12-05T05:00:00Z A common criticism of xenotransplantation is that the immunosuppression protocols required are too toxic for use in humans. Success for pig-to-baboon heart transplants 2018-12-04T05:00:00Z I realise that it is really a major step forward in heart xenotransplantation. Listen: Pig-heart transplants in baboons work for longer than ever before 2018-12-04T05:00:00Z Elliott, R. B. Towards xenotransplantation of pig islets in the clinic. Pancreas regeneration 2018-05-15T04:00:00Z There are no major remaining scientific hurdles to xenotransplantation, and pig organs will eventually be able to keep people alive and healthy, believes Bruno Reichart, a heart surgeon who led the Nature study. Do animals hold the key to the global organ shortage? 2019-04-03T04:00:00Z The approach is different to xenotransplantation, in which an organ that belongs to another species is transplanted into humans. Breakthrough as scientists grow sheep embryos containing human cells 2018-02-17T05:00:00Z But the progress made by Längin and colleagues moves clinical heart xenotransplantation nearer to becoming a reality. Success for pig-to-baboon heart transplants 2018-12-04T05:00:00Z Perhaps in the near future, you’ll be listening to this podcast reporting the first successful xenotransplantation, and with it, the next step in medical science. Listen: Pig-heart transplants in baboons work for longer than ever before 2018-12-04T05:00:00Z To be a commercial hit, xenotransplantation “must touch tens and hundreds of thousands of people,” she says. Scientists grow bullish on pig-to-human transplants 2017-09-22T04:00:00Z Cleveland wants to use xenotransplantation to save babies born with congenital heart defects. Do animals hold the key to the global organ shortage? 2019-04-03T04:00:00Z Beyond the yuck factor, however, there are real, physiological objections to such “xenotransplantation”. Gene editing may make pigs into organ donors for people 2017-08-09T04:00:00Z Darren Griffin, a genetics professor at the University of Kent, said: "This represents a significant step forward towards the possibility of making xenotransplantation a reality. " GM pigs take step to being organ donors - BBC News 2017-08-10T04:00:00Z That’s because there’s another major problem with xenotransplantation that this paper doesn’t address: the danger of organ rejection. How turning off viruses in piglets could make their organs safer for people 2017-08-10T04:00:00Z “We are pushing the envelope of technology day by day. I think that such innovation is required to tackle as challenging a problem as xenotransplantation.” Gene-Editing Success Brings Pig-to-Human Transplants Closer to Reality 2017-08-10T04:00:00Z Researchers are also anxious about how the public will perceive xenotransplantation, although early polling suggests people are open to the concept. Do animals hold the key to the global organ shortage? 2019-04-03T04:00:00Z The scenario described by the reporter was almost certainly impossible, but the incident represents some of the ethical questions around transplanting organs between species, or xenotransplantation. Goat testicles in men, human organs in pigs: the past and future of xenotransplantation 2017-06-16T04:00:00Z Gene editing has revitalised research into xenotransplantation, and the concept of using animal organs for humans. Scientists grow human organs for transplant inside pigs - BBC News 2016-06-05T04:00:00Z In October, researchers set a record by editing the genomes of pig embryos in 62 places at once — a move that could help to revitalize the field of xenotransplantation. 365 days: The science events that shaped 2015 2015-12-16T05:00:00Z The challenges proved too daunting, and in the early 2000s Novartis killed its xenotransplantation programme, reshuffling or laying off its researchers. New life for pig-to-human transplants 2015-11-09T05:00:00Z See More » In the 1990s, researchers explored the possibility of using pig organs in humans, a technique known as xenotransplantation. Editing of Pig DNA May Lead to More Organs for People 2015-10-15T04:00:00Z Ultimately, though, FitzGerald thinks that xenotransplantation doesn’t have to be an end in itself. Goat testicles in men, human organs in pigs: the past and future of xenotransplantation 2017-06-16T04:00:00Z Pig-to-human transplants are part of a field known as xenotransplantation, and are thought to be one of the best solutions to the dire shortage of organ donors worldwide. Gene editing could make pig organs suitable for human transplant one day 2015-10-14T04:00:00Z Prof Church says the discovery holds great promise for using animal organs in people - what doctors call xenotransplantation. 'GM could make pig organs for humans' - BBC News 2015-10-12T04:00:00Z It became, Pierson says, “the third rail of biotech to discuss xenotransplantation as a business plan”. New life for pig-to-human transplants 2015-11-09T05:00:00Z Church’s success isn’t necessarily good news, says one veteran xenotransplantation researcher. Gene-editing method revives hopes for transplanting pig organs into people 2015-10-11T04:00:00Z Once, attempts at xenotransplantation meant putting chimpanzee kidneys in humans, which usually wasn’t successful. Goat testicles in men, human organs in pigs: the past and future of xenotransplantation 2017-06-16T04:00:00Z In addition, in vivo dilution xenotransplantation assays were performed in NOD/SCID/Il2rγ mice. XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway 2014-04-04T18:28:18.449Z The proposed law went beyond the directive, calling for a ban on xenotransplantation and the use of animals in addiction research. Biomedicine: The changing face of primate research 2014-02-05T18:21:10.713Z Novartis initially planned to spend more than $1 billion on xenotransplantation, including both scientific research and planning the infrastructure that would be needed to grow pigs in germ-free facilities around the world. New life for pig-to-human transplants 2015-11-09T05:00:00Z This will require systematically testing variations in xenotransplantation assay conditions, including the addition of variables such as human cytokines that might influence human-cell engraftment. Tumour heterogeneity and cancer cell plasticity 2013-09-18T17:21:13.347Z |
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