| 单词 | vaccinia |
| 例句 | This vaccine is also based on vaccinia virus, however the version of the vaccinia virus in the ACAM2000 vaccine is able to replicate in a person’s cells. 6 Questions About Monkeypox Vaccines 2022-08-08T04:00:00Z The Jynneos vaccine is given in two doses four weeks apart and contains a live vaccinia virus. A virologist explains how — and how well — the monkeypox vaccine works 2022-08-06T04:00:00Z But vaccinia copies itself after vaccination, which can lead to serious disease, especially in people who have compromised immune systems from HIV—which has a high prevalence among MSM—or other factors. There’s a shortage of monkeypox vaccine. Could one dose instead of two suffice? 2022-06-30T04:00:00Z Yet the vast majority of existing smallpox vaccines consist still replicating vaccinia. As monkeypox threat grows, scientists debate best vaccine strategy 2022-06-07T04:00:00Z But the vaccine contains live vaccinia virus, and causes about six cases of myopericarditis — inflammation of the heart muscle — for every 1,000 people who receive it. 21 Americans Infected With Monkeypox, C.D.C. Reports 2022-06-03T04:00:00Z The vaccine contained a labmade virus called vaccinia that replicates inside the recipient and sometimes caused severe side effects, killing one in 1 million vaccinated people. Monkeypox outbreak questions intensify as cases soar 2022-05-20T04:00:00Z This vaccine is also based on vaccinia virus, however the version of the vaccinia virus in the ACAM2000 vaccine is able to replicate in a person's cells. A virologist explains how — and how well — the monkeypox vaccine works 2022-08-06T04:00:00Z One, named ACAM2000, is a modern version of the age-old smallpox vaccine, made from unmodified vaccinia virus, that helped eradicate that disease from humans, a feat WHO celebrated as complete in 1980. There’s a shortage of monkeypox vaccine. Could one dose instead of two suffice? 2022-06-30T04:00:00Z These can cause rare but life-threatening side effects such as encephalitis or progressive vaccinia, the spread of the vaccine virus to the whole body, to which immunocompromised people are vulnerable. As monkeypox threat grows, scientists debate best vaccine strategy 2022-06-07T04:00:00Z Those who cannot safely take either tecovirimat or brincidofovir — people who are immunocompromised, for example — can be given an immune therapy called vaccinia immunoglobulin, but only limited quantities exist. 21 Americans Infected With Monkeypox, C.D.C. Reports 2022-06-03T04:00:00Z The other, from Bavarian Nordic, uses a nonreplicating form of vaccinia, specifically designed to cause fewer side effects. Monkeypox outbreak questions intensify as cases soar 2022-05-20T04:00:00Z This subset includes the smallpox, vaccinia and cowpox viruses. What is Monkeypox, the Virus Infecting People in the U.S. and Europe? 2022-05-20T04:00:00Z The Centers for Disease Control and Prevention said Thursday that testing showed the vials contain “vaccinia, the virus used in smallpox vaccine” and not the variola virus, which causes smallpox. CDC: Vials contain no trace of virus that causes smallpox 2021-11-19T05:00:00Z And many contacts of those infected are living with HIV, which could make them more likely to suffer from vaccinia side effects. As monkeypox threat grows, scientists debate best vaccine strategy 2022-06-07T04:00:00Z Since it relies on activating the immune response with live smallpox variola virus, inoculation is different from the modern vaccination that eradicated smallpox using the much less harmful but related vaccinia virus. Colonial America was divided over smallpox inoculation, but Benjamin Franklin championed science 2021-07-06T04:00:00Z The first to be invented, the smallpox vaccine, used a live vaccinia virus—one similar enough to the original infectious agent, but not quite. Can We Really Develop a Safe, Effective Coronavirus Vaccine? 2020-04-06T04:00:00Z Gilbert’s team uses a crippled vaccinia virus that can infect human cells and that synthesizes two different immunity-stimulating influenza proteins but is incapable of further replication. Towards a universal flu vaccine 2019-09-17T04:00:00Z Later vaccines were made using a purified form of the vaccinia virus. 'Surprise' as teenager catches cowpox 2018-06-15T04:00:00Z The vaccine is made from a live virus called vaccinia, which is a poxvirus that is similar to smallpox but less harmful. FDA cracks down on stem-cell clinics, including one using smallpox vaccine in cancer patients 2017-08-28T04:00:00Z The vaccine contains live vaccinia virus, related to cowpox and smallpox. Smallpox vaccine used in risky cancer therapy seized from San Diego stem cell company 2017-08-28T04:00:00Z Unlike its disease-causing counterpart, which killed about 300 million people in its heyday, the vaccinia virus caused only mild symptoms in healthy patients. Can We Really Develop a Safe, Effective Coronavirus Vaccine? 2020-04-06T04:00:00Z Indeed, Gilbert is exploring the potential of a broader immunological assault that melds the Mount Sinai group’s chimaeric stem vaccine with her team’s vaccinia technique. Towards a universal flu vaccine 2019-09-17T04:00:00Z In its request, the company said it was conducting cancer research involving the vaccinia virus, and needed to vaccinate researchers — a seemingly legitimate reason. F.D.A. Cracks Down on ‘Unscrupulous’ Stem Cell Clinics 2017-08-28T04:00:00Z Notably, as compared with normal cells, cells engineered to lack MER41 were more susceptible to infection by the vaccinia virus, used to inoculate people against smallpox. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z He is trying to develop cancer vaccines and wants to use a vaccinia virus — another relative of smallpox, often used in research — as a way to introduce cancer fighters to the immune system. Scientists Recreated an Extinct Virus 2017-07-10T04:00:00Z The vaccine used to eradicate smallpox--the world's oldest vaccine--is itself a living virus named vaccinia; it was first used in 1796 by Edward Jenner, an English doctor. How Canadian researchers built a poxvirus for $100,000 using mail-order DNA 2017-07-06T04:00:00Z Drake says Listeria is easier to grow in culture than vaccinia and fowlpox. Therapy: An immune one-two punch : Nature : Nature Publishing Group 2015-12-14T05:00:00Z Variolation was used into the twentieth century, especially in poorer communities, although in the nineteenth century many physicians switched to vaccinating with the related, but much less harmful, vaccinia virus. Infectious diseases: Smallpox watch 2014-04-30T17:20:30.360Z An engineered form of vaccinia — the viral agent that helped eradicate smallpox — is being tested against advanced liver cancer, the third leading cause of cancer deaths globally. In Theory: Viruses Are Recruited and Flipped as Cancer Killers 2012-03-19T19:44:45Z Typhoid fever may also be complicated with rubeola, pertussis, diphtheria, variola, and vaccinia. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z But there are also stories implicating horsepox, and the published horsepox genome looks very similar to some old vaccinia strains, bolstering the hypothesis that the vaccine was derived from horses. How Canadian researchers built a poxvirus for $100,000 using mail-order DNA 2017-07-06T04:00:00Z The acquired antitoxin lasts after smallpox, vaccinia, yellow fever, scarlet fever, measles, typhoid, mumps, and whooping-cough; it is very transient after pneumonia, influenza, diphtheria, erysipelas, and cholera. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z Suddenly, the live vaccinia virus, the milder relative of smallpox used in the vaccination, was able to multiply into a dangerous infection. Biodefence: The price of protection 2011-09-07T17:20:26.127Z Smallpox vaccines are made from vaccinia, a milder related virus. Experts debate destroying last smallpox viruses 2011-05-13T12:24:07Z When vaccination is practised after the disease is fully developed, the two disorders, vaccinia and variola, apparently concur, and proceed pari passu to the evolution peculiar to each. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z The study in the journal Science says researchers used the vaccinia virus which was used to eradicate smallpox. 2010-01-22T00:25:00Z By vaccinating a person we inoculate him with vaccinia or cowpox. Essays In Pastoral Medicine 2012-03-05T03:00:09.993Z Cattle and men, if inoculated from a case of horsepox, develop vaccinia, but vaccinia from the latter animals is not so readily reinoculated into the horse with success. Special Report on Diseases of the Horse The view that vaccinia is attenuated variola is well known, and has been extensively adopted by English physicians. Scientific American Supplement, No. 421, January 26, 1884 The older writers, indeed, bestowed no little attention upon what they considered to be not irregular forms of vaccinia, but distinct affections with which it was liable to be confounded. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z The eminence on which we stood was overgrown with vaccinia and other plants, and we saw among them marks of its being visited by hares. Journal of a Voyage from Okkak, on the Coast of Labrador, to Ungava Bay, Westward of Cape Chudleigh Undertaken to Explore the Coast, and Visit the Esquimaux in That Unknown Region The inoculation of man with the contents of such a vesicle produces a mild form of disease known as vaccinia, which protects the individual from smallpox. Disease and Its Causes Cline inoculated a young tubercular patient with vaccinia and later with smallpox in no less than three places. Popular Science Monthly Oct, Nov, Dec, 1915 — Volume 86 The analogy between this process and the accepted view of vaccinia is very close. Scientific American Supplement, No. 421, January 26, 1884 Concerning those cases of generalized vaccinia that are manifestly not eruptive, it sometimes happens that the cutaneous receptivity is not exhausted for several weeks, or even months. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z This test, however, is not altogether trustworthy, for a renewed susceptibility to vaccinia by inoculation does not necessarily imply that the liability to take small-pox by effluvium has been regained. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z This protection is fully as adequate as that produced by an attack of smallpox, and we are warranted in saying that if thorough vaccination, or the inoculation with vaccinia, were carried out smallpox would disappear. Disease and Its Causes Jenner believed vaccinia to be the same pathological entity as human smallpox, modified, however, by its transmission through the cow. Popular Science Monthly Oct, Nov, Dec, 1915 — Volume 86 Given a typical vaccinia, we may unhesitatingly answer, No; but do we now so invariably produce the disease in all its essential features as was done in Jenner's time? A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z Retro-vaccine—i.e. the virus of an affection produced in the cow by the inoculation of vaccinia from the human subject. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z Besides immunity from small-pox, there are one or two sequel� of vaccinia that deserve mention before we proceed to consider what it is better to class as complications. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z In the human subject vaccinia occurs generally as the result of intentional inoculation, as will be more fully referred to when we come to the consideration of vaccination. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z Cowpox, or vaccinia, though infectious for cows, is not transmissible among human beings, in other words, as a disease of man it is not infectious. Popular Science Monthly Oct, Nov, Dec, 1915 — Volume 86 The identity of vaccinia and "grease" is certainly much more doubtful. Popular Science Monthly Oct, Nov, Dec, 1915 — Volume 86 What has been termed generalized vaccinia is another form of irregularity. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z In 1788 Jenner had a careful drawing made of the hand of a milkmaid suffering from cowpox to demonstrate to Sir Everard Home how exceedingly similar were vaccinia and variola. Popular Science Monthly Oct, Nov, Dec, 1915 — Volume 86 The boy had the usual "reaction" or attack of vaccinia, a disorder indistinguishable from the mildest form of smallpox. Popular Science Monthly Oct, Nov, Dec, 1915 — Volume 86 It is only when we contrast the loathsomeness and danger of smallpox with the mildness and safety of vaccinia and varioloid that we grasp the greatness of the work which Jenner did for mankind. Popular Science Monthly Oct, Nov, Dec, 1915 — Volume 86 The child had a slight illness, very like vaccinia, from which he rapidly recovered. Popular Science Monthly Oct, Nov, Dec, 1915 — Volume 86 SEQUEL� AND COMPLICATIONS.—The most important sequela of vaccinia is the fact that it protects the subject against small-pox, and on that circumstance hinges the chief practical interest of the disease. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z |
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