单词 | transposable |
例句 | Unlike many action directors, who often see their actors as transposable parts, Scott worked repeatedly with some of Hollywood's most acclaimed performers. Director Tony Scott may have been ill 2012-08-21T04:29:03Z The piano versions are, of course, transposable, and hearing them in higher registers and keys sheds new light on their expressive potential. Röschmann/Bostridge/Drake – review 2013-04-09T17:01:36Z The C-Fern appears to have gained its large genome primarily from repetitive DNA and transposable elements — “jumping genes” that often move around in chromosomes, with a function that is poorly understood. Cracking the Case of the Giant Fern Genome 2022-09-12T04:00:00Z Alu sequences can move around the genome and are sometimes called jumping genes or transposable elements. ‘Jumping gene’ may have erased tails in humans and other apes—and boosted our risk of birth defects 2021-09-21T04:00:00Z Some 44 percent of human genes are transposable elements—“jumping genes” that can change position in a genome. The Ocean Carries ‘Memories’ of SARS-CoV-2 2020-08-15T04:00:00Z Overlapping transposable elements belonging to the same repeat class were collated and combined. Genome sequence of the progenitor of wheat A subgenome Triticum urartu 2018-05-08T04:00:00Z We find widespread accessible chromatin regions in early human embryos that overlap extensively with putative cis-regulatory sequences and transposable elements. Chromatin analysis in human early development reveals epigenetic transition during ZGA 2018-05-01T04:00:00Z A unified classification system for eukaryotic transposable elements. Genome sequence of the progenitor of the wheat D genome Aegilops tauschii 2017-11-14T05:00:00Z Much of the focus on transposable elements—and particularly, on endogenous retroviruses and LINE-1s—has centered on the possible negative repercussions of these DNA insertions. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z The scripts, parameters, and intermediate files of each transposable element superfamily are available at https://github.com/mcstitzer/maize_v4_TE_annotation. Improved maize reference genome with single-molecule technologies : Nature : Nature Research 2017-06-11T04:00:00Z After an initial annotation, previously unclassified or poorly characterized transposable element families were re-analysed and new consensus sequences were constructed. A chromosome conformation capture ordered sequence of the barley genome : Nature : Nature Research 2017-04-25T04:00:00Z However, the component subgenomes of a polyploid must cooperate to mediate potential incompatibilities of dosage, regulatory controls, protein–protein interactions and transposable element activity. Genome evolution in the allotetraploid frog Xenopus laevis : Nature : Nature Research 2016-10-18T04:00:00Z It is a transposable element—a piece of DNA that leaps from place to place in the genome. Peppered moths 2016-06-02T04:00:00Z He did not expect his team's first discovery there to come so swiftly, or that it would involve transposable elements. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z As large-scale expansion and movement of transposable elements are known to increase under genomic stress24, this may suggest that Ss4R caused transposable element expansion by compromising regulatory processes responsible for transposon policing. The Atlantic salmon genome provides insights into rediploidization : Nature : Nature Publishing Group 2016-04-17T04:00:00Z The observed distribution of different types of transposable elements around genes may reflect selective pressures, allowing only the smallest elements, namely Mariners, to be tolerated closest to genes. A chromosome conformation capture ordered sequence of the barley genome : Nature : Nature Research 2017-04-25T04:00:00Z He explored crafting a gene drive method using transposable elements, odd bits of DNA that can jump among chromosomes, but never succeeded. Gene drive turns insects into malaria fighters 2015-11-23T05:00:00Z Finally, we found evidence for large-scale genomic rearrangements that are closely associated with transposable element expansions. The octopus genome and the evolution of cephalopod neural and morphological novelties : Nature : Nature Publishing Group 2015-08-11T04:00:00Z The other type of transposable elements, known as retrotransposons, are more abundant in our genome. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z The distribution of pairwise per cent similarity, a proxy for time, between members of a family was used to analyse the temporal dynamics of transposable element activity. The Atlantic salmon genome provides insights into rediploidization : Nature : Nature Publishing Group 2016-04-17T04:00:00Z For the analysis of transposable element content in up- and downstream regions of genes, 10 kb immediately flanking the predicted coding sequences of all high-confidence genes were extracted from the genome assembly. A chromosome conformation capture ordered sequence of the barley genome : Nature : Nature Research 2017-04-25T04:00:00Z Heterochromatin also reins in transposable elements: segments of DNA that jump from place to place in our genomes. Relaxed DNA may contribute to aging 2015-04-30T04:00:00Z Crick and his colleagues argued that transposable elements were common in our genome not because they did something essential for us, but because they could exploit us for their own replication. Is Most of Our DNA Garbage? 2015-03-05T05:00:00Z The risks of transposable elements to human health are a concern when it comes to the tissue transplants we receive from other species, such as from pigs, which have porcine endogenous retroviruses. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z Groupings are based on whether one gene copy lies within 20 kb up or downstream of a TE. b, Orientation bias of transposable elements within or near non-duplicated genes. The genomic substrate for adaptive radiation in African cichlid fish : Nature : Nature Publishing Group 2014-09-02T04:00:00Z The gibbon genome contains all previously described classes of transposable elements that are mostly also present in other primates. Gibbon genome and the fast karyotype evolution of small apes : Nature : Nature Publishing Group 2014-09-09T04:00:00Z “There is very little that is transposable from one molecule to the next,” Slaoui said. Can the Nervous System Be Hacked? 2014-05-23T04:00:00Z Gould delighted at this good intellectual company, arguing that transposable elements behaved like miniature organisms, evolving to become better at adding new copies to their host genomes. Is Most of Our DNA Garbage? 2015-03-05T05:00:00Z The gene is thought to exist in multiple versions in the squirrel monkey genome thanks to transposable elements. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z Groupings are based on whether one gene copy lies within 20 kb up or downstream of a TE. b, Orientation bias of transposable elements within or near non-duplicated genes. The genomic substrate for adaptive radiation in African cichlid fish : Nature : Nature Publishing Group 2014-09-02T04:00:00Z The assemblies were masked using RepeatMasker, and gene predictions were omitted from further analyses if at least one base of their coding parts overlapped with an annotated transposable element. The genome of the recently domesticated crop plant sugar beet (Beta vulgaris) 2014-01-22T18:21:48.441Z Gene families involved in resistance to oxidation, carbohydrate metabolism and defence against transposons are significantly expanded, which may explain why transposable elements cover only 3% of the assembled sequence. Genomic evidence for ameiotic evolution in the bdelloid rotifer Adineta vaga 2013-08-21T17:50:58.107Z Other pieces, called transposable elements, were like parasites, simply making new copies of themselves that were usually inserted harmlessly back in the genome. Is Most of Our DNA Garbage? 2015-03-05T05:00:00Z Squirrel monkeys are not the only animals that might reap protection against viral invaders thanks in part to changes in the genome caused by transposable elements. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z Comparative sequencing of Pinus sylvestris, Abies sibirica, Juniperus communis, Taxus baccata and Gnetum gnemon reveals that the transposable element diversity is shared among extant conifers. The Norway spruce genome sequence and conifer genome evolution 2013-05-29T17:21:22.577Z In contrast, the zebrafish genome contains a marked excess of type II DNA transposable elements. The zebrafish reference genome sequence and its relationship to the human genome 2013-04-24T17:21:53.517Z Some theories predict that transposable elements should be either absent from the genomes of asexuals or undergo unrestrained expansion after the switch to asexuality, potentially leading to species extinction unless transposable element proliferation is prevented. Genomic evidence for ameiotic evolution in the bdelloid rotifer Adineta vaga 2013-08-21T17:50:58.107Z To subtract junk, meanwhile, would require swarms of proteins to chop out every single dead gene or transposable element — without chopping out an essential gene. Is Most of Our DNA Garbage? 2015-03-05T05:00:00Z Interestingly, the cellular machinery involved in keeping cancer at bay might also have a connection to transposable elements. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z Most internal clades with significant bootstrap support were consistently species-specific, indicating that most expansions of extant transposable element families occurred after divergence. The Norway spruce genome sequence and conifer genome evolution 2013-05-29T17:21:22.577Z This pronounced abundance of type II transposable elements is unique among the sequenced vertebrate genomes, and the genome sequence shows evidence of recently active type II transposable elements. The zebrafish reference genome sequence and its relationship to the human genome 2013-04-24T17:21:53.517Z This is consistent with an ongoing process of acquisition of transposable elements by HGT. Genomic evidence for ameiotic evolution in the bdelloid rotifer Adineta vaga 2013-08-21T17:50:58.107Z Over millions of years, the human genome has spontaneously gotten bigger, swelling with useless copies of genes and new transposable elements. Is Most of Our DNA Garbage? 2015-03-05T05:00:00Z She dubbed these jumping bits of genetic code “controlling units,” which later became known as transposons or transposable elements. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z Taken together, these findings indicated that the extant set of transposable elements in accumulated slowly over tens or hundreds of millions years, mainly by the insertion of LTR-RT elements with limited transposable element removal. The Norway spruce genome sequence and conifer genome evolution 2013-05-29T17:21:22.577Z We conclude that the current coelacanth genome shows both an abundance and activity of transposable elements similar to many other genomes. The African coelacanth genome provides insights into tetrapod evolution 2013-04-17T17:21:37.460Z Second, those transposable elements are particularly likely to be endogenous retroviruses, rather than any of the other sorts of element. RNA-only genes: The origin of species? 2012-11-29T17:39:56Z The oyster genome is highly polymorphic and rich in repetitive sequences, with some transposable elements still actively shaping variation. The oyster genome reveals stress adaptation and complexity of shell formation 2012-10-03T18:22:26.103Z The study of transposable elements is a “hotbed of research,” according to Josh Meyer, a postdoctoral fellow who studies these bits of DNA at Oregon Health & Science University in Portland. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z Figure 2: Conifer genomes contain expansions of a diverse set of LTR-RTs. a, Distribution of different classes of transposable elements from six gymnosperm species. The Norway spruce genome sequence and conifer genome evolution 2013-05-29T17:21:22.577Z We next examined the abundance of transposable elements in the coelacanth genome. The African coelacanth genome provides insights into tetrapod evolution 2013-04-17T17:21:37.460Z Their alignments to the genome indicate that both probably silence diverse transposable elements. The genome of Tetranychus urticae reveals herbivorous pest adaptations 2011-11-23T18:21:26.577Z The draft assembly provided insight into a molluscan genome characterized by high polymorphism, abundant repetitive sequences and active transposable elements. The oyster genome reveals stress adaptation and complexity of shell formation 2012-10-03T18:22:26.103Z Since McClintock's breakthrough, researchers have identified different classes of transposable elements in the genomes of every organism in which they have sought them, ranging from fruit flies to polar bears. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z Instead, the large genome size seems to result from the slow and steady accumulation of a diverse set of long-terminal repeat transposable elements, possibly owing to the lack of an efficient elimination mechanism. The Norway spruce genome sequence and conifer genome evolution 2013-05-29T17:21:22.577Z The potato genome was masked by identified repeat sequences longer than 500 bp, except for miniature inverted repeat transposable elements which are usually found near genes or inside introns. Genome sequence and analysis of the tuber crop potato 2011-07-13T17:21:42.673Z Deduction succeeds in things moral only metaphorically, so to speak, and just in the measure in which the moral is transposable into the physical, I should say translatable into spatial symbols. Creative Evolution However, both types of transposable elements contain the code for an enzyme called reverse transcriptase, which theoretically enables them to reinsert genetic code into the genome in the cell nucleus. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z After associating with CHMP3 RNA in the cytoplasm, the transposable elements brought the code for CHMP3 back into the nucleus and reintegrated it into the genome. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z We used plant genome annotations filtered to remove transposable elements. The Norway spruce genome sequence and conifer genome evolution 2013-05-29T17:21:22.577Z Other studies of endogenous viruses might have clearer implications for human health, and so scientists are looking at the activity of these transposable elements in a wide range of other animals, including the house cat. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z We clustered LTRs of complete elements to identify transposable element families. The Norway spruce genome sequence and conifer genome evolution 2013-05-29T17:21:22.577Z Figure 2: Conifer genomes contain expansions of a diverse set of LTR-RTs. a, Distribution of different classes of transposable elements from six gymnosperm species. The Norway spruce genome sequence and conifer genome evolution 2013-05-29T17:21:22.577Z At the same time, experiments also offer mounting data to suggest that some transposable elements—and the genes that these roving bits of DNA help to resurrect—have beneficial roles. Medicine's Movable Feast: What Jumping Genes Can Teach Us about Treating Disease 2017-07-26T04:00:00Z We used plant genome annotations filtered to remove transposable elements. The Norway spruce genome sequence and conifer genome evolution 2013-05-29T17:21:22.577Z |
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