| 单词 | bile acid |
| 例句 | “And these bacteria degrade the bile in the gut into secondary bile acids that are thought to promote the growth of tumours.” Are you eating too much protein? Some sources aren't as healthy as you think 2018-06-04T04:00:00Z The resulting mixture then moves into the small intestine, where it is combined with bile acids and enzymes. Perspective | There’s a persistent myth that you shouldn’t drink water while eating. You can disregard it. 2019-04-19T04:00:00Z The results showed that both sharks can taste bitter substances also perceived by humans, such as colchicine or bile acid. Evolution of taste: Early sharks were able to perceive bitter substances 2023-11-13T05:00:00Z The sharks’ receptors also perked up when exposed to bitter substances that would be created inside their bodies, such as bile acids. Ancient sharks may have pioneered the ability to taste bitterness in food 2023-11-12T05:00:00Z The crucial roles instead seem to be played by bile acids and antimicrobial peptides in the gut, each of which increase markedly after surgery; Seeley is still sorting out the exact mechanisms of their influence. Bariatric Surgery at 16 2023-10-31T04:00:00Z The activities of the bacteria in the intestine in turn influence the bile acid metabolism in the liver. That smell: New gut microbe produces smelly toxic gas but protects against pathogens 2023-09-18T04:00:00Z Cholesterol is an important component of bile acids, compounds that help emulsify dietary fats. Anatomy and Physiology 2013-06-19T00:00:00Z The liver makes bile salts out of cholesterol, so as bile acids are broken down, the organ pulls more cholesterol out of the blood to replace them — lowering the levels of LDL in the blood. The complex relationship between drugs and the microbiome 2020-01-28T05:00:00Z One type of bacteria from the Verrucomicrobia phylum, Akkermansia muciniphila, seemed to play a role in a healthy aging process, the researchers say, possibly by increasing the amounts of secondary bile acids in the gut. Poop transplants can help prematurely old mice live longer 2019-07-29T04:00:00Z Soluble fiber binds to bile acids, substances produced by the liver that aid in digestion and fat absorption, and it helps your body excrete them. Fiber has surprising anti-aging benefits, but most people don’t eat enough of it 2018-04-27T04:00:00Z The results of the Viennese researchers therefore also contribute to a better understanding of these complex interactions in bile acid metabolism, which has an impact on processes and diseases throughout the body. That smell: New gut microbe produces smelly toxic gas but protects against pathogens 2023-09-18T04:00:00Z Indeed, by altering the site and timing of bile-nutrient mix within the intestine, this surgery influences the interaction of bile acids with other components of intestinal content, thereby changing their chemical characteristics. Readers Respond to the July 2017 Issue 2017-11-05T04:00:00Z One major hormonal change is in bile acids. After Weight-Loss Surgery, a Year of Joys and Disappointments 2016-12-27T05:00:00Z This led them to suspect a link between liver cancer and too much bile acid. Why disrupted body clocks trigger liver cancer 2016-12-01T05:00:00Z Our livers produce compounds called bile acids that help break down fat in the food we eat. Fecal Transplants Can Be Life-Saving, but How? 2016-07-15T04:00:00Z To access sufficient taurine in the gut, however, Taurinivorans muris needs the help of other gut microbes to release it from bile acids. That smell: New gut microbe produces smelly toxic gas but protects against pathogens 2023-09-18T04:00:00Z In that organ, circulating bile acids serve as a feedback mechanism that modulates their own synthesis. Readers Respond to the July 2017 Issue 2017-11-05T04:00:00Z And the relative proportions of the different bile acids change immediately with surgery. After Weight-Loss Surgery, a Year of Joys and Disappointments 2016-12-27T05:00:00Z One of bile’s main components is bile acid, a derivative of cholesterol. Why disrupted body clocks trigger liver cancer 2016-12-01T05:00:00Z Mechanistic links between bile acids and bariatric surgery demonstrate that functional FXR signalling is required for a reduction in body weight and an improvement in glucose tolerance after vertical sleeve gastrectomy90. Diet-microbiota interactions as moderators of human metabolism : Nature : Nature Publishing Group 2016-07-05T04:00:00Z Schematic summarizes the cholate-derived bile acid metabolism in the mammalian intestine. Culturing of ‘unculturable’ human microbiota reveals novel taxa and extensive sporulation : Nature : Nature Publishing Group 2016-05-03T04:00:00Z As I discussed in my article, however, surgery's effect on diabetes is likely the result of a combination of various changes in GI mechanisms, not of bile acids by themselves. Readers Respond to the July 2017 Issue 2017-11-05T04:00:00Z Around one-quarter of IBS-D cases are caused by excess bile acid, which is produced by the liver to help with the digestion of fats. Drug development: A healthy pipeline : Nature : Nature Publishing Group 2016-05-17T04:00:00Z This gene is activated when levels of bile acid get too high. Why disrupted body clocks trigger liver cancer 2016-12-01T05:00:00Z Some of the beneficial effects of bariatric surgery might therefore be mediated by the altered microbial metabolism of bile acids, which affects their capacity for signalling. Diet-microbiota interactions as moderators of human metabolism : Nature : Nature Publishing Group 2016-07-05T04:00:00Z Schematic summarizes the cholate-derived bile acid metabolism in the mammalian intestine. Culturing of ‘unculturable’ human microbiota reveals novel taxa and extensive sporulation : Nature : Nature Publishing Group 2016-05-03T04:00:00Z A recent study published in the journal Nutrition Research compared the bile acid binding capacity of steamed collard greens to Cholestyramine, a cholesterol-lowering drug. 25 Best Foods for an Instant Detox 2015-12-31T05:00:00Z Problems also occur when too much bile acid is produced, or if too little is absorbed in the small intestine. Drug development: A healthy pipeline : Nature : Nature Publishing Group 2016-05-17T04:00:00Z A few of the bacteria highlighted in the study are known to be involved in metabolizing bile acids that affect cholesterol levels. Gut Bugs May Affect Body Fat, 'Good' Cholesterol Levels 2015-09-10T04:00:00Z The liver produces bile acids to help the intestine absorb fats, which help manage fat and sugar metabolism. How what we eat is destroying our livers 2015-07-02T04:00:00Z This leads to reduced bile flow, potentially poisonous buildup of bile acid products in the liver and less absorption of fats and vitamins. Cholbam Approved for Rare Metabolic Disorders 2015-03-18T04:00:00Z Other inherited metabolic diseases besides PKU include urea cycle disorders in which the body cannot eliminate the ammonia resulting from normal protein metabolism and the bile acid disorder known as Crigler–Najjar syndrome. With Liver Donors in Short Supply, Cell Transplants Offer New Options 2015-02-17T05:00:00Z Clinical pharmacologist Norman Z. Nyazema published experiments in the 1980s while at the University of Zimbabwe showing that crocodile bile was non-toxic and contained many of the same bile acids that humans use for digestion. Deadly 'Crocodile Bile' Brew Poison Identity Inconclusive, Says Mozambique Official 2015-01-29T05:00:00Z Bile contains detergent molecules, called bile salts or bile acids, that animals use to dissolve or emulsify fats. Did Crocodile Bile In Beer Really Kill 69 People In Mozambique? 2015-01-12T05:00:00Z Other groups have shown that C. scindens makes enzymes that chemically alter the bile acids made in the liver, transforming them into so-called secondary bile acids in the large intestine. Bile-making microbe fights off germ behind chronic diarrhea 2014-10-22T04:00:00Z The first compound was in seven Phase II studies in four different diseases caused by the accumulation of high levels of bile acids that ultimately result in liver failure, he said. UPDATE 1-Shire buys Lumena Pharma for at least $260 mln 2014-05-12T18:09:19Z Intercept’s drug is a slightly modified form of a bile acid, a component of the bile that helps in digestion. Promising Drug Trial Lifts Stock of Intercept 2014-01-10T02:56:48Z In the gut, certain types of microbes convert bile acids — which aid in fat digestion — to the more harmful DCA, which is then absorbed into the bloodstream and delivered to the liver. Gut Microbes Spur Liver Cancer in Obese Mice 2013-06-27T19:15:05.723Z New conditions in their bodies — such as a change in bile acids — allowed a different set of gut bacteria to thrive. Gut-Microbe Swap Helps with Weight Loss 2013-03-27T22:15:10.067Z And these secondary bile acids have been shown to inhibit C. difficile growth in a dish. Bile-making microbe fights off germ behind chronic diarrhea 2014-10-22T04:00:00Z Primary bile acids are conjugated to taurine in mice and to glycine in humans, and are taken up in the distal ileum for transport to the liver. Functional interactions between the gut microbiota and host metabolism 2012-09-13T11:21:18.130Z Tochtrop, assistant professor of chemistry and pharmacology at Case Western Reserve University, studies bile acids, which are made by the liver and secreted by the gallbladder into the small intestine during digestion. Studying Digestive Health 2012-08-13T14:25:00Z It is composed of a mixture of the sodium salts of the bile acids. Webster's Unabridged Dictionary (2nd 100 Pages) 2012-03-24T02:00:19.387Z In the former pigment, bile acids, and cholesterin may also be present. A System of Practical Medicine by American Authors, Vol. I Volume 1: Pathology and General Diseases 2012-03-17T02:00:54.097Z C. scindens also increased the abundance of secondary bile acids in the gut, Pamer and his colleagues report online today in Nature. Bile-making microbe fights off germ behind chronic diarrhea 2014-10-22T04:00:00Z It’s thought to lower cholesterol by binding to bile acids and removing them from the body. Foods that are good?and bad?for your heart 2012-02-07T00:33:00Z Producing bile acids “is the major usage of cholesterol in the body,” he adds. Studying Digestive Health 2012-08-13T14:25:00Z This compound absorbs bile acids and prevents the reabsorption of cholesterol from the digestive tract. People's Pharmacy: ER trip from amoxicillin 2011-11-02T21:18:03Z Under the latest deal, Bristol-Myers will be responsible for research, development, manufacturing and commercialization of a small-molecule drug program that targets TGR5, a bile acid receptor, with potential for treatment for diabetes. Exelixis licenses two drug programs to Bristol 2010-10-11T16:55:00Z It is likewise believed to be the “mother substance” from which bile acids are derived. Dietetics for Nurses Limbeck, that in catarrhal jaundice a considerable increase of volume of the red blood corpuscles comes to pass under the influence of the salts of the bile acids. Histology of the Blood Normal and Pathological “If you understand bile acid metabolism, you understand cholesterol metabolism.” Studying Digestive Health 2012-08-13T14:25:00Z In fact, the first generation of cholesterol-lowering drugs tried to exploit this mechanism by preventing the recycling of bile acids. Studying Digestive Health 2012-08-13T14:25:00Z Human bacteria that live in the intestine--and everyone’s bacteria are different--interact with the bile acids to change their makeup. Studying Digestive Health 2012-08-13T14:25:00Z |
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