| 单词 | telomere |
| 例句 | The presence of telomerase meant cells could keep regenerating their telomeres indefinitely. The Immortal Life of Henrietta Lacks 2010-02-02T00:00:00Z This process correlates with the age of a person: the older we are, the shorter our telomeres, and the fewer times our cells have left to divide before they die. The Immortal Life of Henrietta Lacks 2010-02-02T00:00:00Z By the early nineties, a scientist at Yale had used HeLa to discover that human cancer cells contain an enzyme called telomerase that rebuilds their telomeres. The Immortal Life of Henrietta Lacks 2010-02-02T00:00:00Z They also knew that there was a string of DNA at the end of each chromosome called a telomere, which shortened a tiny bit each time a cell divided, like time ticking off a clock. The Immortal Life of Henrietta Lacks 2010-02-02T00:00:00Z As normal cells go through life, their telomeres shorten with each division until they’re almost gone. The Immortal Life of Henrietta Lacks 2010-02-02T00:00:00Z Thing is, as your cells replicate, telomeres get shorter over time, according to the University of Utah Health Sciences. 4 Foods That May Shorten Your Life 2014-11-01T04:00:00Z "Research has shown that people who eat more nuts and seeds have longer telomeres, which means that eating nuts can slow down our cellular aging," he continued. National Nut Day: Health benefits of pistachios, almonds, cashews and more revealed 2021-10-22T04:00:00Z While the researchers didn’t find a tie between telomeres and non-sugary diet soda, it might not be any better for you. 4 Foods That May Shorten Your Life 2014-11-01T04:00:00Z Genetics: Presently, the telomeres determine maximum age; gene therapy is increasingly patching the software bugs which cause diseases 2. 12 Tips for Living a Longer Life 2015-08-04T04:00:00Z More red meat in the rats’ diet was linked to decreased telomere length in colon cells. 4 Foods That May Shorten Your Life 2014-11-01T04:00:00Z However, each time a cell divides, the telomeres inside those cells become slightly shorter. Greener neighborhoods can protect us -- at the cellular level 2023-10-18T04:00:00Z Some of the plasmids that end up in the exclusome originate from outside the cell, while others -- known as telomeric rings -- come from the capped ends of chromosomes, the telomeres. A hygiene program for chromosomes 2023-10-02T04:00:00Z Patent absurdity, of course, as much then as now — no matter how many 3D-printed organs we churn out, how long we extend our telomeres, nor how many quaffs of plasma we down. Bloodthirsty Silicon Valley vampires won't stop: It's time to stake our claim 2023-08-27T04:00:00Z It looks to measure gene structures called telomeres that protect human chromosomes, but which shorten with age and wear. Launch sends space-plant babies, ‘blue jet’ lightning research to space station 2023-06-05T04:00:00Z When it comes to slowing aging in humans, telomeres have long been a tempting target. Scientists prevent signs of aging in zebrafish by targeting the gut 2023-05-18T04:00:00Z Once the telomeres become so short that the cell cannot divide successfully, the cell dies. Greener neighborhoods can protect us -- at the cellular level 2023-10-18T04:00:00Z The ends of the linear chromosomes are known as telomeres, which have repetitive sequences that do not code for a particular gene. Concepts of Biology 2013-04-25T00:00:00Z The caps on chromosomes, called telomeres, are chains of short, repeated segments of DNA. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z In the Kelly twin study, these telomeres were only able to be measured while Scott Kelly was on Earth and not during his yearlong stay on the station. Launch sends space-plant babies, ‘blue jet’ lightning research to space station 2023-06-05T04:00:00Z When researchers lengthened telomeres in the gut cells of these tiny, translucent fish, they reversed signs of aging in the entire organism. Scientists prevent signs of aging in zebrafish by targeting the gut 2023-05-18T04:00:00Z "And we know that many variables -- such as stress -- can influence how quickly our telomeres wear down." Greener neighborhoods can protect us -- at the cellular level 2023-10-18T04:00:00Z The darkly staining regions usually contain genes that are not active, and are found in the regions of the centromere and telomeres. Concepts of Biology 2013-04-25T00:00:00Z And a paper published Thursday in the New England Journal of Medicine, with results of a study that Dr. Armanios led, shows that the telomere story is no exception. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z The careful consideration that characterizes the beginning of the novel — scientific discussions of telomeres, well-imagined political scenarios and futurist tech talk — soon dissolves into hasty tropes, however. Review | Jaroslav Kalfar’s new novel asks: Do we really want to live forever? 2023-03-28T04:00:00Z “It’s a really good paper,” says Ronald DePinho, a cancer biologist at the MD Anderson Cancer Center who studies telomeres and aging. Scientists prevent signs of aging in zebrafish by targeting the gut 2023-05-18T04:00:00Z In addition, the researchers identified a suite of other environmental variables that could affect telomere length, such as air quality and "redlining" maps that track historically segregated neighborhoods. Greener neighborhoods can protect us -- at the cellular level 2023-10-18T04:00:00Z As a consequence, it is telomeres that are shortened with each round of DNA replication instead of genes. Concepts of Biology 2013-04-25T00:00:00Z While short telomeres do lead to health problems, long telomeres lead to health problems of their own. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z In normal cells, continued rounds of replication shorten telomeres until they become so short that they eventually trigger the cell to stop replicating. How cancer cells can become immortal 2022-11-24T05:00:00Z During embryonic development, an enzyme called telomerase lengthens telomeres in order to allow cells to divide more often. Scientists prevent signs of aging in zebrafish by targeting the gut 2023-05-18T04:00:00Z The markers in question are telomeres, which are sections of repetitive DNA found at each end of a chromosome that serve to protect the ends of the chromosomes from damage. Greener neighborhoods can protect us -- at the cellular level 2023-10-18T04:00:00Z Adult somatic cells that undergo cell division continue to have their telomeres shortened. Concepts of Biology 2013-04-25T00:00:00Z Far from extending life, long telomeres appear to cause cancer and a blood disorder known as CHIP, a condition that increases the risk of blood cancers and heart disease. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z In contrast, tumor cells can maintain the lengths of their telomeres by activating an enzyme called telomerase that rebuilds telomeres during each replication. How cancer cells can become immortal 2022-11-24T05:00:00Z Recent studies in humans have also suggested that, although short telomeres cause inflammation, long telomeres carry a higher risk of cancer. Scientists prevent signs of aging in zebrafish by targeting the gut 2023-05-18T04:00:00Z Specifically, the researchers looked at data on 7,827 people that allowed them to assess their demographic data, the length of their telomeres, and where they lived. Greener neighborhoods can protect us -- at the cellular level 2023-10-18T04:00:00Z It happens throughout our lives, triggered by things such as DNA damage and the shortening of telomeres, structures that cap and protect the ends of chromosomes. ‘Zombie’ cells may hold clues to improving old age 2022-09-09T04:00:00Z They found correlations — not a cause and effect — with increased disease risks at either end of the normal telomere spectrum. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z We are researchers who study the role telomeres play in human health and diseases like cancer in the Alder Lab at the University of Pittsburgh. How cancer cells can become immortal 2022-11-24T05:00:00Z Ferreira says these swimmers—about the diameter of a penny—are a good model for aging because their telomeres are naturally about the same length as those of humans. Scientists prevent signs of aging in zebrafish by targeting the gut 2023-05-18T04:00:00Z The research team assessed the amount of greenspace in each person's neighborhood and how that related to their telomere length. Greener neighborhoods can protect us -- at the cellular level 2023-10-18T04:00:00Z It happens throughout our lives, triggered by things like DNA damage and the shortening of telomeres, structures that cap and protect the ends of chromosomes. Zombie cells central to the quest for active, vital old age 2022-08-30T04:00:00Z She suspected, she said, that “you just can’t elongate telomeres without a price,” and began looking for people with very long telomeres to ask what that price might be. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z While investigating the ways that tumors maintain their telomeres, we and our colleagues found another piece to the puzzle: another telomere-associated gene in melanoma. How cancer cells can become immortal 2022-11-24T05:00:00Z That made sense, Ferreira says: Cells in the gut divide frequently in order to regenerate the organ’s lining, and therefore tend to have shorter telomeres than most other cell types. Scientists prevent signs of aging in zebrafish by targeting the gut 2023-05-18T04:00:00Z The ends of the linear chromosomes are known as telomeres, which have repetitive sequences that code for no particular gene. Biology for AP Courses 2022-06-09T00:00:00Z At the ends of these chromosomes are repetitive stretches of DNA called telomeres that form a protective cap to prevent damage to the genetic material. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z They ranged in age from 7 to 83 and had extraordinarily long telomeres. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z Our team focused on melanoma because this type of cancer is linked to people with long telomeres. How cancer cells can become immortal 2022-11-24T05:00:00Z This lengthened telomeres in the gut and restored cells’ ability to proliferate and replace damaged tissue. Scientists prevent signs of aging in zebrafish by targeting the gut 2023-05-18T04:00:00Z In a way, these telomeres protect the genes from getting deleted as cells continue to divide. Biology for AP Courses 2022-06-09T00:00:00Z However, telomeres shorten each time a cell divides. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z Harriet Brown, 73, of Frederick, Md., is one of the study participants with very long telomeres. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z We examined DNA sequencing data from hundreds of melanomas, looking for mutations in genes related to telomere length. How cancer cells can become immortal 2022-11-24T05:00:00Z Telomerase adds short, repeated DNA sequences to telomeres during replication, and helps prevent the genes near the ends of chromosomes from getting lost or damaged during replication. Miller & Levine Biology 2018-01-01T00:00:00Z Heterochromatin usually contains genes that are not expressed, and is found in the regions of the centromere and telomeres. Biology for AP Courses 2022-06-09T00:00:00Z This means that as cells divide more and more as you age, your telomeres become increasingly shorter and more likely to lose their ability to protect your DNA. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z Or, as Dr. Blackburn observed: Long telomeres are not the secret to eternal youth. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z This gene codes for one of the six proteins that form a molecular complex called shelterin that coats and protects telomeres. How cancer cells can become immortal 2022-11-24T05:00:00Z The tips of eukaryotic chromosomes are called telomeres. Miller & Levine Biology 2018-01-01T00:00:00Z This essentially means that telomere shortening is associated with aging. Biology for AP Courses 2022-06-09T00:00:00Z We wanted to know if direct damage to telomeres can be sufficient to trigger senescence and make zombie cells. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z Every time a cell divides, its telomeres get a little shorter, until finally they get so short that the cell dies. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z Identifying the TPP1 gene's connection to cancer telomeres was, in a way, obvious. How cancer cells can become immortal 2022-11-24T05:00:00Z Studies have also demonstrated a link between stress, such as the effects of daily discrimination, and degradation of telomeres, sequences of DNA at the end of chromosomes, Davis Moss said. Tension over role of racism in public health strains Va. agency under Youngkin 2022-06-15T04:00:00Z Thus, telomere reactivation may have potential for treating age-related diseases in humans. Biology for AP Courses 2022-06-09T00:00:00Z In order to figure this out, we needed to confine damage just to the telomeres. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z When scientists started studying telomeres, they observed that young people had longer ones than older people. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z When we introduced just TPP1 proteins into cells, there was no change in cell mortality or telomere length. How cancer cells can become immortal 2022-11-24T05:00:00Z Another study by the same lead researcher found Black women had shorter telomeres than White women, suggesting an environmental cause. Tension over role of racism in public health strains Va. agency under Youngkin 2022-06-15T04:00:00Z Scientists have observed that cancerous cells have considerably shortened telomeres and that telomerase is active in these cells. Biology for AP Courses 2022-06-09T00:00:00Z So we attached a protein to the telomeres of human cells grown in the lab. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z When cells are grown in the lab, their telomeres act as sort of a ticking clock, determining how long they have to live. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z While this is still a significant proportion of melanomas, there are likely other factors that contribute to telomere maintenance in this cancer. How cancer cells can become immortal 2022-11-24T05:00:00Z Some of the gaps were on telomeres, the caps at the ends of chromosomes that have often been compared to the aglets that protect the ends of shoelaces. Human blueprint breakthrough: Scientists publish ‘gapless’ human genome 2022-03-31T04:00:00Z Interestingly, only after the telomeres were shortened in the cancer cells did the telomerase become active. Biology for AP Courses 2022-06-09T00:00:00Z We found that direct damage to the telomeres was sufficient to turn cells into zombies, even when these protective caps weren't shortened. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z Soon, telomeres were hailed as a secret to aging — companies advertised that they could tell your biological age by measuring the length of your telomeres. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z Our findings imply that TPP1 is likely one of the missing puzzle pieces that boost telomerase's capacity to maintain telomeres and support tumor growth and immortality. How cancer cells can become immortal 2022-11-24T05:00:00Z Their efforts yielded a truly complete human genome sequence, from telomere to telomere of every human chromosome. Completing the Human Genome Sequence (Again) 2022-03-31T04:00:00Z However, the roles of telomeres and telomerase in aging and cancer are informative and build on your knowledge of DNA replication in prokaryotes. Biology for AP Courses 2022-06-09T00:00:00Z The reason for this, we discovered, was likely a result of disrupted DNA replication at the telomeres that leaves chromosomes even more susceptible to damage or mutations. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z Others said that you could extend your life by preserving your telomeres with supplements. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z Knowing that cancer use these genes in their replication and growth means that researchers could also block them and potentially stop telomeres from lengthening and make cancer cells mortal. How cancer cells can become immortal 2022-11-24T05:00:00Z The group, named after the sections at the very ends of chromosomes, called telomeres, is known as the Telomere-to-Telomere, or T2T, consortium. Scientists finally finish decoding entire human genome 2022-03-31T04:00:00Z In humans, this is the repeated, telomeric sequence that is attached to the telomere. Biology for AP Courses 2022-06-09T00:00:00Z Our study reveals that telomeres not only serve as alarm clocks that indicate a cell divided too many times, but also as warning bells for harmful levels of oxidative stress. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z But Dr. Armanios and other researchers had noticed that telomere lengths seemed constrained to a narrow range, indicating there is a price to pay for very long or very short telomeres. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z And, eventually, Phillippy says, “We want every genome to be telomere to telomere.” Most complete human genome yet reveals previously indecipherable DNA 2022-03-30T04:00:00Z Their telomeres, the chromosome caps that shrink over time, also shortened faster than in normal rodents. Glitchy protein production may hasten aging 2022-03-01T05:00:00Z Neither the boar nor the snakes showed signs that their telomeres had shortened because of radiation, and the boars' cortisol levels were quite low. Animals near Fukushima are doing surprisingly well despite radiation from nuclear accident 2021-10-19T04:00:00Z Age-related shortening of telomeres isn't the only thing that triggers senescence; telomere damage is also sufficient to turn a cell into a zombie. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z Those with shorter than average telomeres appeared to have an increased risk of immune system problems and a variety of degenerative diseases, as well as pulmonary fibrosis, a lung disease. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z Scientists also saw unexpected changes in "caps" on the ends of Scott's chromosomes, called telomeres, as well as shifts in his blood chemistry, body mass and gut flora. Astronaut Scott Kelly: How to survive a year in space 2020-12-24T05:00:00Z Shorter telomeres are a marker of accelerated biological aging, according to Science Alert, which reported on the new research this week. 'Ultra-processed' foods could accelerate biological aging, study finds 2020-09-03T04:00:00Z Each time a cell divides to drive growth and repair, its telomeres shorten. Effective Psychological Therapy May Slow Cellular Aging 2020-04-20T04:00:00Z Researchers are studying treatments and interventions that can protect telomeres from damage and prevent zombie cell accumulation. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z Those with longer than average telomeres appeared to have a modestly increased risk of cancer. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z Some clues already exist4 about these factors, such as the presence of long versions of structures called telomeres, found at the ends of chromosomes, and high expression levels of the protein CD27 in T cells. Identifying the source of tumour-infiltrating T cells 2019-12-10T05:00:00Z Meanwhile, telomeres shorten with each cell division, even as life style affects the degree of shrinkage—data now suggest that “married people, or people living with a partner, have longer telomeres.” Why We Can’t Tell the Truth About Aging 2019-10-28T04:00:00Z A longer study might show changes to telomeres themselves; nine weeks was too short for that, according to Månsson. Effective Psychological Therapy May Slow Cellular Aging 2020-04-20T04:00:00Z This study focuses on the consequences of telomere damage in actively dividing cells, like kidney and skin cells. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z “Some organisms have crazy long telomeres, like mice,” said Dr. Benjamin Ebert, chairman of medical oncology at the Dana-Farber Cancer Institute. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z When telomeres get too short, cells die and stop replicating. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z Aging is not caused by one event, however, as compelling as fraying telomeres may be. Perspective | Five myths about aging 2019-09-20T04:00:00Z Of particular interest are the bats’ telomeres, the protective end caps of chromosomes that in most mammals — including humans — shorten as they age. What bats, primates and even zebrafish tell us about human aging 2019-06-14T04:00:00Z While researchers have shown that the telomeres of nondividing cells and tissues become more dysfunctional with age, it's unclear why this happens when these telomeres should not be shortening in the first place. Cells become zombies when the ends of their chromosomes are damaged 2022-07-23T04:00:00Z She decided to look for people with a common genetic mutation, POT1, that can result in long telomeres. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z Shorter telomeres are associated with an increased risk of cardiovascular disease, cancer, diabetes and other health conditions. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z Some of our cells do not divide at all, and they age without shortened telomeres. Perspective | Five myths about aging 2019-09-20T04:00:00Z Yet the telomeres of the Myotis myotis bats stayed the same size year after year, Telling’s team found. What bats, primates and even zebrafish tell us about human aging 2019-06-14T04:00:00Z Probably the strangest finding concerned telomeres, which are the protective ends of chromosomes. Weird science: NASA's twins study reveals the strange effects of spaceflight on the body 2019-04-12T04:00:00Z It was known to increase cancer risk but most researchers thought it was for reasons other than lengthening telomeres. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z Although telomeres are known to shorten in all humans with age, certain things, such as cigarette smoking, a high body mass index and major stress may accelerate the shortening process. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z Shortening telomeres may even be useful, protecting against unchecked cell division, which is a hallmark of cancer. Perspective | Five myths about aging 2019-09-20T04:00:00Z But space is no fountain of youth: The telomeres shortened dramatically when he returned to Earth. NASA Kelly twins study shows harsh effects of space flight and a brutal return to Earth 2019-04-11T04:00:00Z In space, however, Scott Kelly's telomeres got longer. Weird science: NASA's twins study reveals the strange effects of spaceflight on the body 2019-04-12T04:00:00Z “It’s not that long telomeres make cells grow,” he said. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z Good sleep, regular exercise and a Mediterranean diet have been associated with longer telomeres. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z In another test, the researchers scrutinized molecular caps on the ends of Mr. Kelly’s chromosomes, called telomeres. 4 Takeaways From That Huge Study of Scott Kelly 2019-04-11T04:00:00Z The cause of these changes in telomere length is unclear, said Susan M. Bailey, a biologist at Colorado State University who led that part of the study. NASA Kelly twins study shows harsh effects of space flight and a brutal return to Earth 2019-04-11T04:00:00Z "We were surprised," said Colorado State University telomere expert Susan Bailey. Weird science: NASA's twins study reveals the strange effects of spaceflight on the body 2019-04-12T04:00:00Z And because the telomeres of people with POT1 mutations do not grow shorter with each cell division, the cells hang around, dividing regularly. Link Between Long Telomeres and Long Life Is a Tall Tale, Study Finds 2023-05-04T04:00:00Z However, they did not find the same effect when they looked at telomere length. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z But Mr. Kelly’s telomeres actually grew longer on average during his time in space. 4 Takeaways From That Huge Study of Scott Kelly 2019-04-11T04:00:00Z Scott Kelly, who along with his brother Mark was on the call, interjected that previous experiments had found that worms have longer telomeres in space. NASA Kelly twins study shows harsh effects of space flight and a brutal return to Earth 2019-04-11T04:00:00Z Instead, perhaps his body manufactured a new supply of young cells with longer telomeres. Scott Kelly Spent a Year in Orbit. His Body Is Not Quite the Same. 2019-04-11T04:00:00Z After returning home, the telomere elongation was replaced by accelerated shortening and loss, a potentially negative consequence for cellular health, they said. Oh, brother! NASA twins study shows how space changes the human body 2019-04-11T04:00:00Z The researchers found that women who had live births had telomeres that were an average of 4.2 percent shorter than their counterparts with no children. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z For example, why did his telomeres get longer? 4 Takeaways From That Huge Study of Scott Kelly 2019-04-11T04:00:00Z Although his average telomere length returned roughly to normal after he returned to Earth, tests showed that he retained a slightly elevated number of cells with short telomeres. NASA Kelly twins study shows harsh effects of space flight and a brutal return to Earth 2019-04-11T04:00:00Z The strange lengthening of Mr. Kelly’s telomeres disappeared after less than 48 hours on Earth. Scott Kelly Spent a Year in Orbit. His Body Is Not Quite the Same. 2019-04-11T04:00:00Z Shrinking telomeres Susan Bailey, a professor of radiation cancer biology at Colorado State University-Fort Collins, took an even closer look at the DNA. Scott Kelly’s year in space highlights risks to DNA and brains 2019-04-11T04:00:00Z Strikingly, this decrease in telomere length is greater than what researchers have previously found in people who smoke cigarettes or have a high body mass index. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z While in flight, Kelly’s telomeres—the protective sequences of repeating nucleotides that “cap” the ends of each chromosome like aglets on a shoelace—grew longer. Tests on Astronaut and Twin Brother Highlight Spaceflight's Human Impact 2019-04-11T04:00:00Z Many of the caps at the ends of Scott’s chromosomes, called telomeres, also mysteriously lengthened during spaceflight, says Bailey. Astronaut twins study spots subtle genetic changes caused by space travel 2019-04-10T04:00:00Z Dr. Bailey studied special sections of his DNA called telomeres, which sit at the end of chromosomes, protecting them from deterioration. Scott Kelly Spent a Year in Orbit. His Body Is Not Quite the Same. 2019-04-11T04:00:00Z Telomeres shorten as we age and with stress, and shortened telomeres have been linked to age-related diseases like cardiovascular disease. Scott Kelly’s year in space highlights risks to DNA and brains 2019-04-11T04:00:00Z Estrogen may serve as an antioxidant that prevents the shortening of telomeres. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z But in space, Scott Kelly’s telomeres got longer. NASA twins study explores space, the final genetic frontier 2019-04-11T04:00:00Z Thus, the state of a cell's telomeres tells much about its biological “age,” and shortened telomeres that produce frayed, vulnerable chromosomes seem to be a molecular version of wear and tear. How Economic Inequality Inflicts Real Biological Harm 2019-02-25T05:00:00Z His cells might not have grown longer telomeres, in other words. Scott Kelly Spent a Year in Orbit. His Body Is Not Quite the Same. 2019-04-11T04:00:00Z So in the stressful environment of spaceflight, you’d expect telomeres to shrink. Scott Kelly’s year in space highlights risks to DNA and brains 2019-04-11T04:00:00Z The results were similar to what the telomeres indicated: The more pregnancies a woman went through, the “older” her epigenetic age. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z “We were surprised,” said Colorado State University telomere expert Susan Bailey. NASA twins study explores space, the final genetic frontier 2019-04-11T04:00:00Z Spend your childhood in poverty, and by middle age your telomeres will probably be about a decade older than those with more fortunate childhoods. How Economic Inequality Inflicts Real Biological Harm 2019-02-25T05:00:00Z As people age, their telomeres tend to get shorter. Scott Kelly Spent a Year in Orbit. His Body Is Not Quite the Same. 2019-04-11T04:00:00Z Instead, Bailey’s team found that Scott Kelly’s telomeres lengthened. Scott Kelly’s year in space highlights risks to DNA and brains 2019-04-11T04:00:00Z He would also like to analyze telomere length in women before and after pregnancy, to see how it changes. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z Its focus is on treatments that can lengthen telomeres – the “caps” at the end of each strand of DNA. Is Silicon Valley's quest for immortality a fate worse than death? 2019-02-23T05:00:00Z It found that sedentary, middle-aged people who took up aerobic exercise for six months developed longer telomeres in their white blood cells. Year in Fitness: How Exercise Keeps Us Young 2018-12-26T05:00:00Z In fact, Dr. Bailey and her colleagues started finding many cells with telomeres that were shorter than before Mr. Kelly went to space. Scott Kelly Spent a Year in Orbit. His Body Is Not Quite the Same. 2019-04-11T04:00:00Z Weirder still, Scott’s telomeres shrank as soon as he landed. Scott Kelly’s year in space highlights risks to DNA and brains 2019-04-11T04:00:00Z At least one study on telomere length of American women has found results along the lines of what Eisenberg and Ryan found. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z Because our cells copy themselves throughout our lives, the telomeres eventually get very short, and our cells cannot regenerate: we get old. Is Silicon Valley's quest for immortality a fate worse than death? 2019-02-23T05:00:00Z Lengthy telomeres, on the other hand, are thought to denote relative cell youth and vigor. Year in Fitness: How Exercise Keeps Us Young 2018-12-26T05:00:00Z Stress — such as radiation or pollution — may hasten aging by fraying telomeres even faster than usual. Scott Kelly Spent a Year in Orbit. His Body Is Not Quite the Same. 2019-04-11T04:00:00Z By nine months out, the team saw more missing or seriously shortened telomeres than they did before. Scott Kelly’s year in space highlights risks to DNA and brains 2019-04-11T04:00:00Z It is purely hypothesis, he said, but the community support may reduce stress levels in mothers and result in increased telomere length. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z “If you can get the telomeres back to the normal state they were at when you were born, that could reduce your biological age back to 25,” Strole said. Is Silicon Valley's quest for immortality a fate worse than death? 2019-02-23T05:00:00Z But that study was associational; it showed only that older people who ran also were people with extended telomeres, not that the exercise necessarily caused that desirable condition. Is Aerobic Exercise the Key to Successful Aging? 2018-12-12T05:00:00Z Strangely, the average length of Mr. Kelly’s telomeres increased in space, rather than decreasing, as if his cells were becoming more youthful. Scott Kelly Spent a Year in Orbit. His Body Is Not Quite the Same. 2019-04-11T04:00:00Z Bailey’s team wanted to know what a year in space would do to the structures at the ends of Scott Kelly’s chromosomes, called telomeres. Scott Kelly’s year in space highlights risks to DNA and brains 2019-04-11T04:00:00Z The increased telomere length could also be due to the dramatic increase in estrogen in women who are pregnant, Nepomnaschy said. Do pregnancy and childbirth accelerate aging in women? Maybe. 2019-10-18T04:00:00Z Writing in 2018, she claimed a measurement of her telomeres showed they had “grown younger” by roughly 30 years since she received the treatment – her body was reverse-aging. Is Silicon Valley's quest for immortality a fate worse than death? 2019-02-23T05:00:00Z Those men and women who had jogged or completed intervals had much longer telomeres in their white blood cells now than at the start, and more telomerase activity. Is Aerobic Exercise the Key to Successful Aging? 2018-12-12T05:00:00Z Dr. Bailey, for her part, plans to keep on studying Mr. Kelly’s baffling telomeres. Scott Kelly Spent a Year in Orbit. His Body Is Not Quite the Same. 2019-04-11T04:00:00Z Most of the parasite’s VSG-encoding gene repertoire occurs in tandem arrays close to DNA sequences called telomeres, which are found at the ends of chromosomes13; these arrays are known as subtelomeric arrays. Chromatin clues to the trypanosome parasite’s uniform coat 2018-10-16T04:00:00Z They also used the technique to move stretches of DNA known as telomeres—the tips of chromosomes implicated in aging. Moving DNA to a different part of the nucleus can change how it works 2018-10-11T04:00:00Z Among Sierra Sciences competitors is BioViva, whose CEO, Elizabeth Parrish, is so committed to the cause that she became one of the first humans to undergo telomere therapy in 2015. Is Silicon Valley's quest for immortality a fate worse than death? 2019-02-23T05:00:00Z Their telomeres resembled those of people in the control group, having remained about the same or, in some instances, shortened during the six months. Is Aerobic Exercise the Key to Successful Aging? 2018-12-12T05:00:00Z In normal cells, telomeres shorten with time, until the cells are no longer able to divide. The genomics of brain cancer 2018-09-25T04:00:00Z These are regions of chromosomes next to telomeres that are specialized for the expression of VSG-encoding genes. Chromatin clues to the trypanosome parasite’s uniform coat 2018-10-16T04:00:00Z When they moved the telomeres to the inner edge of the nucleus, the cell grew much more slowly, if at all. Moving DNA to a different part of the nucleus can change how it works 2018-10-11T04:00:00Z The gene, known as POT1, affects the length of telomeres — repetitive sequences of DNA at the ends of chromosomes that help to protect genes. Searching for the roots of brain cancer 2018-09-25T04:00:00Z Those who did resistance training would have produced less of a substance, nitric oxide, that is thought to affect the activity of telomerase and contribute to lengthening telomeres. Is Aerobic Exercise the Key to Successful Aging? 2018-12-12T05:00:00Z But in tumours, telomeres remain long, conferring immortality on cells. The genomics of brain cancer 2018-09-25T04:00:00Z The telomeres of T. brucei are located near the outermost region of the nucleus16, termed the nuclear periphery, and it is probable that the silent VSG-encoding arrays are located there, too. Chromatin clues to the trypanosome parasite’s uniform coat 2018-10-16T04:00:00Z But when they put telomeres close to cajal bodies, aggregations of proteins and genetic material that process RNA, the cell perked up: It grew faster and divided sooner than usual. Moving DNA to a different part of the nucleus can change how it works 2018-10-11T04:00:00Z A. The theory that shortened telomeres limit the life span of animals, including humans, is widely studied, with more and more studies lending support. How a Plant Ages 2018-08-27T04:00:00Z Some researchers have speculated that the most pervasive anti-aging effects of exercise may occur at the tips of our chromosomes, which are capped with tiny bits of matter known as telomeres. Is Aerobic Exercise the Key to Successful Aging? 2018-12-12T05:00:00Z These two mechanisms contribute to telomere maintenance in many forms of cancer. The genomics of brain cancer 2018-09-25T04:00:00Z However, the presence of highly complex DNA sequences in the regions that surround telomeres and centromeres in these organisms will make this a challenging task. Yeast chromosome numbers minimized using genome editing 2018-07-31T04:00:00Z Thus, the researchers conclude, the positioning of the telomeres is very important to keeping a cell healthy and productive. Moving DNA to a different part of the nucleus can change how it works 2018-10-11T04:00:00Z The telomere is no small thing, at least not figuratively: Their length is correlated with many symptoms of aging. How summer and diet damage your DNA, and what you can do 2018-07-22T04:00:00Z Many scientists believe that telomere length is a useful measure of a cell’s functional age. Is Aerobic Exercise the Key to Successful Aging? 2018-12-12T05:00:00Z “They’re clearly important. I mean, telomeres are involved in cellular aging. You can only go through so many generations of most cells because of that.” Cracking the Code of Life—at Light Speed 2018-04-27T04:00:00Z To function correctly, yeast chromosomes need protective structures called telomeres at both ends, and only one centromere — a region that ensures the accurate segregation of chromosomes into mother and daughter cells during cell division. Yeast chromosome numbers minimized using genome editing 2018-07-31T04:00:00Z Nevertheless, mutations in those components impair telomere maintenance and cause diseases related to telomerase deficiency2. Detailed view of human telomerase enzyme invites rethink of its structure 2018-04-24T04:00:00Z With every year, your telomeres get shorter, some cells stop replicating, and these symptoms worsen. How summer and diet damage your DNA, and what you can do 2018-07-22T04:00:00Z But researchers also have found that telomeres are mutable. Is Aerobic Exercise the Key to Successful Aging? 2018-12-12T05:00:00Z There are cellular measurements such as % functioning mitochondria, IGF levels, telomere length etc. The Clinical Trial Is Open. The Elderly Need Not Apply. 2018-04-13T04:00:00Z In S. cerevisiae, each chromosome must have protective structures known as telomeres at both ends, as well as a single structure called a centromere that is essential for normal chromosome segregation during cell division. Yeast chromosome numbers minimized using genome editing 2018-07-31T04:00:00Z In a follow-up study, he also looked at the length of telomeres, which are caps at the end of chromosomes that are measured in immune cells. Why Do Some People Get Sick Less Often? 2018-03-24T04:00:00Z This explains why over 85 percent of all cancers exhibit extended telomeres. How summer and diet damage your DNA, and what you can do 2018-07-22T04:00:00Z Their telomeres were, in fact, almost as lengthy of those of healthy, young people. Is Aerobic Exercise the Key to Successful Aging? 2018-12-12T05:00:00Z Other researchers noticed changes in Scott’s body mass, telomere length and cognition over the course of the mission and after it; most shifts were not lasting. Despite what you may have heard, astronauts Mark and Scott Kelly are still twins 2018-03-16T04:00:00Z Most of the observed increases in gene expression can be explained by there being fewer genes located near telomeres, which promote transcriptional silencing4. Yeast chromosome numbers minimized using genome editing 2018-07-31T04:00:00Z As people get older, their telomeres get shorter, resulting in greater risk for all manner of diseases. Why Do Some People Get Sick Less Often? 2018-03-24T04:00:00Z When we fail to use UV protective sunscreen to safeguard our telomeres, we are, quite literally, flying too close to the sun. How summer and diet damage your DNA, and what you can do 2018-07-22T04:00:00Z So for the new study, which was published in November in the European Heart Journal, many of the same scientists involved in the 2009 study decided to directly test whether exercise would change telomeres. Is Aerobic Exercise the Key to Successful Aging? 2018-12-12T05:00:00Z The changes occurred in what’s known as the telomere, a cap of genetic material that sits at the end of each chromosome. No, Scott Kelly's Year in Space Didn't Mutate His DNA 2018-03-15T04:00:00Z The protective caps on the ends of his DNA strands — known as telomeres — increased while in space. No, space did not permanently alter 7 percent of Scott Kelly’s DNA 2018-03-15T04:00:00Z “Looking at telomeres is basically looking at the aging of the immune system,” he says. Why Do Some People Get Sick Less Often? 2018-03-24T04:00:00Z This, in turn, wears away at your telomeres. How summer and diet damage your DNA, and what you can do 2018-07-22T04:00:00Z A 2009 study, for instance, found that middle-aged competitive runners tended to have much longer telomeres than inactive people of the same age. Is Aerobic Exercise the Key to Successful Aging? 2018-12-12T05:00:00Z Normally, telomeres shrink with age, the idea being that each time a chromosome is copied during cell division, the process chips away at that cap. No, Scott Kelly's Year in Space Didn't Mutate His DNA 2018-03-15T04:00:00Z Childhood abuse seems to erode telomeres—the caps at the end of chromosomes, associated with cell preservation—and that, in turn, may accelerate aging. Two psychologists followed 1000 New Zealanders for decades. Here’s what they found about how childhood shapes later life 2018-02-01T05:00:00Z This includes the tips of chromosomes - called telomeres. Handheld device sequences human genome 2018-01-29T05:00:00Z Moreover, it seems diets rich in antioxidants, found in fruits, vegetables, nuts and legumes, which counter that metabolic damage, actually protect telomeres as well. How summer and diet damage your DNA, and what you can do 2018-07-22T04:00:00Z They also checked blood markers of the amount and activity of each person’s telomerase, an enzyme that is known to influence telomere length. Is Aerobic Exercise the Key to Successful Aging? 2018-12-12T05:00:00Z Shortened or frayed telomeres are largely thought to be responsible for age-related cellular breakdown. No, Scott Kelly's Year in Space Didn't Mutate His DNA 2018-03-15T04:00:00Z In 2009, Elizabeth Blackburn received the Nobel Prize for her work on telomeres, protein caps on chromosomes that may be a key to understanding aging. Opinion | The Men Who Want to Live Forever 2018-01-25T05:00:00Z One area of burgeoning research focuses on telomeres. When a Mom Feels Depressed, Her Baby's Cells Might Feel It, Too 2018-01-23T05:00:00Z While our telomere length once seemed pre-determined by our genes, the more medical researchers learn, the more we realize the impact of our lifestyles. How summer and diet damage your DNA, and what you can do 2018-07-22T04:00:00Z Telomere length is seen as a barometer of biological aging, with longer telomeres linked to longevity. Amish Mutation Protects Against Diabetes and May Extend Life 2017-11-15T05:00:00Z But Kelly’s telomeres elongated in space … and then quickly shrank to their original lengths after he returned to Earth. No, Scott Kelly's Year in Space Didn't Mutate His DNA 2018-03-15T04:00:00Z Professor Blackburn’s new book on telomeres couldn’t be clearer. Opinion | The Men Who Want to Live Forever 2018-01-25T05:00:00Z Since the length of telomeres is affected by our genetics and age, they’re sometimes thought of as part of a “biological clock” that reflects the age of our cells. When a Mom Feels Depressed, Her Baby's Cells Might Feel It, Too 2018-01-23T05:00:00Z It is not our telomeres that shorten our lifespans but our lives that shorten our telomeres. How summer and diet damage your DNA, and what you can do 2018-07-22T04:00:00Z One of the most well-hyped measures of biological age involves measuring the length of the ends of DNA, called telomeres. Those ‘biological age’ tests probably can’t tell you how fast you’re aging 2017-11-16T05:00:00Z That these structures exhibit such flexibility is intriguing and potentially quite consequential, says Bailey, whose lab studied Kelly’s telomeres. No, Scott Kelly's Year in Space Didn't Mutate His DNA 2018-03-15T04:00:00Z “Does our research show that by maintaining your telomeres you will live into your hundreds?” it says. Opinion | The Men Who Want to Live Forever 2018-01-25T05:00:00Z As telomeres shorten over time, people are more likely to experience a host of negative health outcomes, such as cardiovascular disease, dementia, diabetes, cancer, obesity and even death. When a Mom Feels Depressed, Her Baby's Cells Might Feel It, Too 2018-01-23T05:00:00Z The one big find so far was that my telomeres, basically these things at the end of our chromosomes that shorten with stress and age, actually ended up longer than Mark’s. Scott Kelly: ‘I came back from space younger than my twin’ 2017-10-29T04:00:00Z They found stronger results than with telomeres or the DNA patterns, but it still wasn’t robust. Those ‘biological age’ tests probably can’t tell you how fast you’re aging 2017-11-16T05:00:00Z I was, for instance, surprised to hear that my telomeres—part of our chromosomes that, as we get older, generally get shorter and more frayed—got better in space compared to his on the ground. Scott Kelly Spent a Year in Space—Find Out How Hard It Was 2017-10-28T04:00:00Z Longer term studies of how the shortened telomeres affect children and teens are also critical. Air Pollution May Make Babies' Cells Age Faster 2017-10-16T04:00:00Z This may be one mechanism that connects psychological stress to telomere length and ultimately physical health. When a Mom Feels Depressed, Her Baby's Cells Might Feel It, Too 2018-01-23T05:00:00Z It’s even been linked to longer telomeres, protein caps on the end of chromosomes that get shorter with age. It’s Official: Happiness Really Can Improve Health 2017-07-20T04:00:00Z Regions containing false positive recurrent events mainly around centromeres and telomeres were excluded from the analysis. The whole-genome landscape of medulloblastoma subtypes : Nature : Nature Research 2017-07-18T04:00:00Z Lundblad, 64, is a cell biologist who made her name studying telomeres, the structures that cap chromosomes. Salk Institute under fire for ‘smear’ on women suing it for discrimination 2017-07-19T04:00:00Z Eventually, when the telomeres become too short, that signals the cell to die. Air Pollution May Make Babies' Cells Age Faster 2017-10-16T04:00:00Z Finally, when the infants were 18 months of age, we brought the families back into our lab and collected saliva to measure the length of the infant’s telomeres. When a Mom Feels Depressed, Her Baby's Cells Might Feel It, Too 2018-01-23T05:00:00Z However, premature loss of telomeres sends cells into senescence — when it no longer divides and grows, and this milestone hastens aging. 2 top female scientists sue Salk Institute for gender discrimination 2017-07-13T04:00:00Z Diet also affects the length of telomeres — protective caps at the end of chromosomes. Some food choices (chocolate!) really may help you age better 2017-07-07T04:00:00Z Salk’s statements about Lundblad are a “character smear,” tweeted telomere biologist Carol Greider, a Nobel laureate at Johns Hopkins University in Baltimore, Maryland. Salk Institute under fire for ‘smear’ on women suing it for discrimination 2017-07-19T04:00:00Z "Shortened telomere length is certainly not a good sign." Air Pollution May Make Babies' Cells Age Faster 2017-10-16T04:00:00Z Normally, telomeres get shorter with each cell division. Rogue chromosome may be behind new contagious cancer striking Tasmanian devils 2017-07-10T04:00:00Z As the basis for these inferences, Ansell cites the growing body of research that links stress to the length of telomeres — caps on chromosomes whose degeneration is associated with shortened lifespan and age-related illnesses. Inequality: Live poor, die young : Nature : Nature Research 2017-05-16T04:00:00Z The capsule also carries 38 shoebox-sized satellites and a high school student's science project that will test how telomeres, which are structures at the ends of chromosomes, are affected by microgravity. U.S. cargo ship blasts off for space station with supplies, experiments 2017-04-18T04:00:00Z A few years ago, there was great excitement about telomeres, Liz Blackburn’s specialty—DNA buffers that protect the ends of chromosomes just as plastic tips protect the ends of shoelaces. Silicon Valley’s Quest to Live Forever 2017-03-27T04:00:00Z Meshing Blackburn's work on telomeres — the chromosomal 'caps' that are biological indicators of life experience — with Epel's research on stress, the volume outlines a regime designed to boost telomerase, the enzyme that replenishes telomeres. Books in brief : Nature : Nature Research 2017-02-14T05:00:00Z The rearrangements may be due to an unusual configuration of telomeres, the caps at the ends of chromosomes that protect them from sticking to each other. Rogue chromosome may be behind new contagious cancer striking Tasmanian devils 2017-07-10T04:00:00Z Abnormally shortened telomeres were not found among women who recorded at least 30 minutes a day of moderate to vigorous physical activity. Lack of activity may be aging you biologically 2017-01-27T05:00:00Z Studies of the twins' telomeres, the caps on the ends of their chromosomes, showed that during spaceflight Scott's telomeres grew to be longer than his brother's. Astronaut twin study hints at stress of space travel 2017-01-25T05:00:00Z As we age, our telomeres become shorter, and, when these shields go, cells stop dividing. Silicon Valley’s Quest to Live Forever 2017-03-27T04:00:00Z The researchers compared telomere length to how much the women exercised, to see if physical activity affected aging. Sitting Too Much Ages You By 8 Years 2017-01-18T05:00:00Z The odd telomeres may explain why the tumor gets started, but not how it infects other devils. Rogue chromosome may be behind new contagious cancer striking Tasmanian devils 2017-07-10T04:00:00Z Those bits are called telomeres, and they’re often compared to the plastic caps on shoelaces. If you want to live longer, take good care of your telomeres 2017-01-13T05:00:00Z Once Scott returned to the ground, the length of his telomeres returned to his pre-flight levels relatively quickly. Astronaut twin study hints at stress of space travel 2017-01-25T05:00:00Z Blackburn is famous for her work on telomeres—the chromosome-capping entities that protect genetic material as it replicates. This Is Why 'Pond Scum' Holds the Secret to Longevity 2016-11-02T04:00:00Z Women who got the recommended amount of daily exercise showed no association between how much time they spent sitting and their telomere length, suggesting that physical activity might counteract the shortening that occurs with aging. Sitting Too Much Ages You By 8 Years 2017-01-18T05:00:00Z It found that the 10 men who followed a program of diet, activity, stress management and social support lengthened their telomeres by about 10% compared with the 25 who didn’t. Mail-Order Tests Check Cells for Signs of Early Aging 2016-10-24T04:00:00Z The bad news is that some people start off at a telomere disadvantage, Blackburn and Epel found. If you want to live longer, take good care of your telomeres 2017-01-13T05:00:00Z A second lab has studied the same samples and confirmed this puzzling increase in telomere length, she says. Astronaut twin study hints at stress of space travel 2017-01-25T05:00:00Z Of course, telomeres are only one piece of the puzzle, Blackburn explained. This Is Why 'Pond Scum' Holds the Secret to Longevity 2016-11-02T04:00:00Z Initially, he did not find any relationship between telomere length and physical activity levels. Sitting Too Much Ages You By 8 Years 2017-01-18T05:00:00Z Studies suggest shorter telomeres are associated with lack of exercise, poor sleep and a diet high in refined carbohydrates, among other factors. Mail-Order Tests Check Cells for Signs of Early Aging 2016-10-24T04:00:00Z Telomerase is an enzyme that is important in regulating and maintaining the health of these telomeres. The Misleading Promise of I.V.F. for Women Over 40 2016-10-17T04:00:00Z Human cells have been rejuvenated by delivering RNA encoding a protein that extends telomeres, protective caps on the ends of chromosomes that are associated with ageing and disease. Human age limit claim sparks debate 2016-10-04T04:00:00Z She also discovered that telomerase, an enzyme plentiful in “pond scum,” but limited in humans, rebuilds telomeres and holds the secret to longevity. This Is Why 'Pond Scum' Holds the Secret to Longevity 2016-11-02T04:00:00Z “Our results suggest that the combination of being sedentary and not engaging in enough physical activity to prevent the telomeres from shortening leads to the shorter telomere length,” says Shadyab. Sitting Too Much Ages You By 8 Years 2017-01-18T05:00:00Z Knowing your telomere length isn’t meant to diagnose a specific disease, they say. Mail-Order Tests Check Cells for Signs of Early Aging 2016-10-24T04:00:00Z Each significant stressful event in a person's childhood appeared to increase the risk of shorter telomeres by 11 percent, Puterman and his colleagues determined from a review of nearly 4,600 people. Can Childhood Traumas Make You Old Before Your Time? 2016-10-03T04:00:00Z But nothing says young like a good set of telomeres. How Childhood Traumas Affect Aging 2016-10-03T04:00:00Z While the health of one’s telomeres correspond with longevity, it’s only one factor, she said. This Is Why 'Pond Scum' Holds the Secret to Longevity 2016-11-02T04:00:00Z Dr. Veronique Bataille, senior author of the paper and also a dermatologist said: "Longer telomeres are likely to be one factor explaining the protection against premature skin aging in individuals who previously suffered from acne." Acne's Silver Lining: Slower Aging of the Skin? 2016-09-29T04:00:00Z The test, which costs $395, measures all 92 telomeres in cell samples, rather than reporting averages, as Telomere Diagnostics does. Mail-Order Tests Check Cells for Signs of Early Aging 2016-10-24T04:00:00Z In this case, telomeres prevent human chromosomes from unraveling, which causes cells to age and die more quickly. Can Childhood Traumas Make You Old Before Your Time? 2016-10-03T04:00:00Z The study found that every occurrence of one of the named social stressors in childhood increased the risk of shortened telomeres in adulthood by 11%. How Childhood Traumas Affect Aging 2016-10-03T04:00:00Z As humans get older and their cells divide over and over again, their telomeres—the protective caps on the end of chromosomes—get shorter. 7 Surprising Benefits of Exercise 2016-09-01T04:00:00Z As cells age, telomeres gradually break down, eventually resulting in cell death, a normal part of growth and aging, the study authors explained. Acne's Silver Lining: Slower Aging of the Skin? 2016-09-29T04:00:00Z Short telomeres are associated with the early onset of disease, though it’s not known whether they actually cause aging. The Future of Aging 2016-08-09T04:00:00Z But the study did not prove that childhood stress causes shorter telomeres, only that there seems to be an association. Can Childhood Traumas Make You Old Before Your Time? 2016-10-03T04:00:00Z Telomeres shorten as cells divide and as people age, and shorter telomeres in adulthood are associated with chronic diseases like diabetes. Breast-Fed Babies May Have Longer Telomeres, Tied to Longevity 2016-08-04T04:00:00Z They found that exercise increased levels of a molecule that protects telomeres, ultimately slowing how quickly they shorten over time. 7 Surprising Benefits of Exercise 2016-09-01T04:00:00Z The latest study did not prove a cause-and-effect link between telomere length and skin aging, however. Acne's Silver Lining: Slower Aging of the Skin? 2016-09-29T04:00:00Z And their telomeres—protective caps on the ends of their chromosomes whose shortening is implicated in ageing—stayed lengthier for longer. Three’s company 2016-07-06T04:00:00Z Dr. Brad Johnson, a spokesman for the American Federation for Aging Research, said that while telomeres do appear to be key to understanding human aging, the effects in this study were "really tiny." Can Childhood Traumas Make You Old Before Your Time? 2016-10-03T04:00:00Z Breast milk contains anti-inflammatory compounds, which may confer a protective effect on telomeres. Breast-Fed Babies May Have Longer Telomeres, Tied to Longevity 2016-08-04T04:00:00Z It’s unclear how widespread this phenomenon is, but shorter telomeres may mean a shorter life expectancy for all city life, including humans. Top stories: Fast-aging birds, how running shoes change your feet, and an encore performance for gravitational waves 2016-06-17T04:00:00Z Regardless of their birthplace, city-raised chicks’ telomeres were 11% shorter than those of chicks raised in the countryside, the team reports today in Biology Letters. This is what city living does to birds 2016-06-14T04:00:00Z Some cells have an enzyme that restores telomeres, but in many cells the telomeres shorten over time until the cell loses the ability to divide. Scientists can make mice live longer. Now they want to do the same for you. 2016-04-18T04:00:00Z "It is much easier and less expensive to ask someone's age than to collect blood, extract DNA and measure telomere length," Glei said in the news release. Predicting Longevity May Be Simpler Than Thought 2016-04-07T04:00:00Z There was no data on telomere length at birth or during the first few months of life. Breast-Fed Babies May Have Longer Telomeres, Tied to Longevity 2016-08-04T04:00:00Z Like the tips found at the end of shoelaces, telomeres protect chromosomes and their critical genetic information from damage. Having More Kids May Slow Mom's Aging, Study Says 2016-01-13T05:00:00Z Although it isn’t clear yet how widespread this phenomenon is, shorter telomeres may mean a shorter life expectancy for all city life, including humans. This is what city living does to birds 2016-06-14T04:00:00Z The notion that telomere wear was the engine of aging had many adherents — until research revealed the story was much more complicated. Scientists can make mice live longer. Now they want to do the same for you. 2016-04-18T04:00:00Z "On the Internet, they sell test-your-own-telomere-length kits and supplements that are touted to help people maintain their telomeres. We caution buyers to beware," Glei added. Predicting Longevity May Be Simpler Than Thought 2016-04-07T04:00:00Z There are several possible explanations for the correlation between breast-feeding and longer telomeres. Breast-Fed Babies May Have Longer Telomeres, Tied to Longevity 2016-08-04T04:00:00Z As people age, telomeres shorten, eventually leading to cell death, according to the U.S. Having More Kids May Slow Mom's Aging, Study Says 2016-01-13T05:00:00Z After 15 days, the team took blood samples to measure the length of each chick’s telomeres—the genetic “cap” at the end of each chromosome that helps protect it from damage. This is what city living does to birds 2016-06-14T04:00:00Z It is true that short telomeres are associated with a higher risk for heart disease, diabetes, some cancers and poor immune function. Scientists can make mice live longer. Now they want to do the same for you. 2016-04-18T04:00:00Z The findings show there is no evidence to suggest that doctors should test telomere length to determine how long patients will live, the study authors said. Predicting Longevity May Be Simpler Than Thought 2016-04-07T04:00:00Z The study did not establish whether or not breast-feeding enhanced telomere length. Breast-Fed Babies May Have Longer Telomeres, Tied to Longevity 2016-08-04T04:00:00Z Their telomere lengths were measured through cheek and saliva swabs taken twice 13 years apart. Having More Kids May Slow Mom's Aging, Study Says 2016-01-13T05:00:00Z One reason why: Exercise lengthens your chromosomes’ protective caps, called telomeres, which determine how quickly your cells age, per 2013 research published in the Lancet Oncology. 14 Reasons to Work Out That Have Nothing to Do With Weight Loss 2015-12-04T05:00:00Z Life stress also appears to shorten telomeres, which may partly explain high disease prevalence in the poor. Scientists can make mice live longer. Now they want to do the same for you. 2016-04-18T04:00:00Z But this new study found that using telomere length was just slightly better than a "coin toss," the researchers said. Predicting Longevity May Be Simpler Than Thought 2016-04-07T04:00:00Z It may be that babies born with longer telomeres are more likely to succeed at breast-feeding. Breast-Fed Babies May Have Longer Telomeres, Tied to Longevity 2016-08-04T04:00:00Z Having sufficiently long telomeres is essential for cells to be able to multiply. Having More Kids May Slow Mom's Aging, Study Says 2016-01-13T05:00:00Z No matter the reason for telomere shortening, boosting the levels of the body’s own telomere-building enzyme, known as telomerase, may help. Four Ways Science is Battling Aging 2015-12-03T05:00:00Z However, people with a rare mutation that keeps telomeres long are more, not less, susceptible to some cancers, such as melanoma. Scientists can make mice live longer. Now they want to do the same for you. 2016-04-18T04:00:00Z She also discovered telomerase, an enzyme that repairs and maintains telomere ends. Elizabeth Blackburn to lead Salk Institute 2015-11-18T05:00:00Z The new study, published in The American Journal of Clinical Nutrition, is a hopeful one, its authors say, because it suggests telomere length in early life may be malleable. Breast-Fed Babies May Have Longer Telomeres, Tied to Longevity 2016-08-04T04:00:00Z The research suggested -- but did not prove -- that giving birth to more children was associated with a slower pace of telomere shortening and increased longevity. Having More Kids May Slow Mom's Aging, Study Says 2016-01-13T05:00:00Z Susan Bailey at Colorado State University will look at blood samples from the twins for evidence that space travel causes damage to the protective caps on chromosomes called telomeres. Nasa astronaut Scott Kelly to break US record for longest space flight 2015-10-28T04:00:00Z “There’s been 20 years of research, and the field has learned that telomere shortening plays a role in aging. But it is not the fundamental cause of aging,” Horvath, the genetics professor, said. Scientists can make mice live longer. Now they want to do the same for you. 2016-04-18T04:00:00Z Perhaps most important, the results don’t tell us whether longer telomeres translate into better health. Does Exercise Slow the Aging Process? 2015-10-28T04:00:00Z Drinking fruit juice every day during the toddler years and a lot of soda at age 4 was also associated with short telomeres. Breast-Fed Babies May Have Longer Telomeres, Tied to Longevity 2016-08-04T04:00:00Z We also found that we could make cells quite miserable if we disrupted their telomeres. Q&A: End-game winner : Nature : Nature Publishing Group 2015-10-20T04:00:00Z This findings show that sugar-sweetened sodas consumed once a day—in a 12-ounce serving—were associated with telomere shortness, a precursor to chronic diseases like diabetes and heart disease. 7 Great Things That Happen to Your Body When You Drop Soda 2015-08-17T04:00:00Z DNA damage, telomere shortening and cell senescence also change methylation patterns. Scientists can make mice live longer. Now they want to do the same for you. 2016-04-18T04:00:00Z However, recent science suggests that exercise may slow the fraying of telomeres. Does Exercise Slow the Aging Process? 2015-10-28T04:00:00Z A major drawback of the research was that telomere length was only measured at one point in time, when the children were 4 or 5 years old. Breast-Fed Babies May Have Longer Telomeres, Tied to Longevity 2016-08-04T04:00:00Z Our lab has been quite good at that ever since telomeres have been on the radar. Q&A: End-game winner : Nature : Nature Publishing Group 2015-10-20T04:00:00Z But telomere length isn’t a malleable factor for most of the population. Study: If You Want To Reach 100, Keep Your Inflammation Levels Low 2015-08-09T04:00:00Z These days they weren’t considered ideal model organisms, although it was not inconceivable given the whole telomere thing from the Winesburg lab that work on them could heat up again. Verge Fiction: Model Organisms 2015-08-02T04:00:00Z It remained unclear whether people of different ages who engaged in a variety of exercises would likewise show effects on their telomeres. Does Exercise Slow the Aging Process? 2015-10-28T04:00:00Z People with long telomeres are at increased risk for lung cancer but not other types of cancer, the researchers found. Scientists Suggest New Way to Predict Lung Cancer Risk 2015-07-29T04:00:00Z We realized that one day, just as you might send off a DNA sample for sequencing, you might also send a sample to a company that could measure your telomeres. Q&A: End-game winner : Nature : Nature Publishing Group 2015-10-20T04:00:00Z These ranged from common measures such as HDL-cholesterol levels and mean arterial blood pressure to more obscure ones like the length of telomeres—the protective caps on the ends of chromosomes that shorten with age. How Quickly Are You Growing Old? 2015-07-13T04:00:00Z Cholesterol, blood pressure, dental status, eye structure and heart health were also assessed, as was the length of chromosomal caps known as telomeres. Some People Do Age Faster Than Others 2015-07-06T04:00:00Z As a cell ages, its telomeres naturally shorten and fray. Does Exercise Slow the Aging Process? 2015-10-28T04:00:00Z "Our work provides compelling evidence of a relationship between long telomeres and increased risk for lung adenocarcinoma," said lead author Brandon Pierce, an assistant professor of public health sciences at the University of Chicago. Scientists Suggest New Way to Predict Lung Cancer Risk 2015-07-29T04:00:00Z I would like to know how a telomere really works. Q&A: End-game winner : Nature : Nature Publishing Group 2015-10-20T04:00:00Z After controlling for a range of socioeconomic, health and lifestyle characteristics, they found that the greater the residents’ degree of unfavorable perceptions about their neighborhoods, the shorter the average telomere length in their cells. Bad Neighborhoods May Be Bad for Your DNA 2015-06-24T04:00:00Z "The differences in telomere length between the two groups were comparable to 12 years in chronological age," Park said. Bad Neighborhoods May Make You Age Faster 2015-06-23T04:00:00Z The researchers then compared those tallies to each person’s telomere length. Does Exercise Slow the Aging Process? 2015-10-28T04:00:00Z "The complex relationship between telomeres and cancer risk is one that we need to further understand," Pierce said in a news release from the University of Chicago Medical Center. Scientists Suggest New Way to Predict Lung Cancer Risk 2015-07-29T04:00:00Z But in live cells, telomeres are extraordinarily dynamic. Q&A: End-game winner : Nature : Nature Publishing Group 2015-10-20T04:00:00Z Each time a cell divides, telomeres becomes shorter, a process associated with aging, illness and death. Bad Neighborhoods May Be Bad for Your DNA 2015-06-24T04:00:00Z Park and her colleagues focused on telomeres, the protective caps on the end of DNA strands on genes. Bad Neighborhoods May Make You Age Faster 2015-06-23T04:00:00Z Lastly, biotech firms are continually unlocking new therapies to treat what were once incurable diseases thanks to genetic mapping and technology advances as well as approaches to lengthen the telomeres in your DNA. Young and Rich? 3 Investing Themes To Consider 2015-05-28T04:00:00Z The results found an association between long telomeres and increased risk of lung cancer, but there was no significant association between telomere length and any of the other types of cancer. Scientists Suggest New Way to Predict Lung Cancer Risk 2015-07-29T04:00:00Z Because of the correlation between long telomeres and a long and healthy life, over the years people have realized that there may be some benefit in measuring the length of their telomeres. Q&A: End-game winner : Nature : Nature Publishing Group 2015-10-20T04:00:00Z Researchers studied 2,981 Dutch people aged 18 to 65, measuring telomere lengths in their white blood cells. Bad Neighborhoods May Be Bad for Your DNA 2015-06-24T04:00:00Z Study investigators describe telomeres as protective "caps" on the end of DNA strands. Age-Linked Structures on DNA May Also Hint at Cancer Risk 2015-05-05T04:00:00Z One of the most important studies involves what are known as telomeres, the cuffs that protect the tips of chromosomes in much the way a plastic aglet protects the tips of shoelaces. The Great Space Twins Study Begins 2015-05-01T04:00:00Z Various age-related diseases are associated with shortened telomeres. Nobelist Talks About Exercise and Chromosome Integrity 2015-04-09T04:00:00Z What are the main unanswered questions involving telomeres? Q&A: End-game winner : Nature : Nature Publishing Group 2015-10-20T04:00:00Z Recent studies have found a link between regular exercise and the lengthening of the telomeres, suggesting that exercise can slow the clock so you live longer. 15 Ways Exercise Makes You Look and Feel Younger 2015-04-04T04:00:00Z "We saw the inflection point at which rapid telomere shortening stabilizes," explained Hou. Age-Linked Structures on DNA May Also Hint at Cancer Risk 2015-05-05T04:00:00Z Chromosomal samples from both Kelly twins were taken and banked before Scott left to provide a telomere baseline, and more samples will be collected over the year. The Great Space Twins Study Begins 2015-05-01T04:00:00Z Elizabeth Blackburn won a Nobel Prize for her discoveries about telomeres and the telomerase enzyme. Nobelist Talks About Exercise and Chromosome Integrity 2015-04-09T04:00:00Z I think we could learn a huge amount by studying telomeres in action, rather like researchers do by watching active ribosomes assemble proteins, in addition to knowing their structure. Q&A: End-game winner : Nature : Nature Publishing Group 2015-10-20T04:00:00Z It has to do with telomeres, the caps at the end of chromosomes that control aging. 15 Ways Exercise Makes You Look and Feel Younger 2015-04-04T04:00:00Z The current study revealed that telomeres start to age at a faster pace than normal in people who eventually develop cancer. Age-Linked Structures on DNA May Also Hint at Cancer Risk 2015-05-05T04:00:00Z Bailey thinks Scott’s telomeres will be shorter than Mark’s after a year in orbit. Astronaut twins study raises questions about genetic privacy 2015-03-25T04:00:00Z They may even lengthen telomeres, the ends of our chromosomes that control aging. The Myth of High-Protein Diets 2015-03-23T04:00:00Z The second unanswered question is how we might be able to modify telomere maintenance to make human bodies more resilient, given the correlation between having long telomeres and living healthily and for a long time. Q&A: End-game winner : Nature : Nature Publishing Group 2015-10-20T04:00:00Z Telomeres become shorter as you get older, and longer telomeres are associated with longevity. 15 Ways Exercise Makes You Look and Feel Younger 2015-04-04T04:00:00Z The study authors said that telomeres belonging to future cancer patients may shorten in length to such a degree that they resemble telomeres belonging to people 15 years older. Age-Linked Structures on DNA May Also Hint at Cancer Risk 2015-05-05T04:00:00Z Meanwhile, Bailey's team will look at telomeres, the caps on the ends of chromosomes that shorten as a person ages. Astronaut twins study raises questions about genetic privacy 2015-03-25T04:00:00Z Aging cells that lack telomerase are more likely to become cancerous; when older cells replicate, their "fraying" chromosomes, unprotected by telomeres, often give birth to cancer-causing mutations. Silicon Valley Is Trying to Make Humans Immortal—and Finding Some Success 2015-03-05T05:00:00Z I had expected to see something similar to the single-strand overhanging DNA observed at the ends of bacteriophage linear DNA, but telomeres were different. Q&A: End-game winner : Nature : Nature Publishing Group 2015-10-20T04:00:00Z It encodes a protein that helps build caps at the ends of DNA molecules called telomeres. In Short-Lived Fish, Secrets to Aging 2015-02-27T05:00:00Z At issue is the shifting status of telomeres in the blood. Age-Linked Structures on DNA May Also Hint at Cancer Risk 2015-05-05T04:00:00Z “Results of the study show childhood adversity and lifetime psychopathology were each associated with shorter telomeres and higher mtDNA content,” read the report. A Rough Childhood Can Literally Age You 2015-01-21T05:00:00Z Dr. Ronald DePinho was interested in telomeres, structures that cap the tips of chromosomes like aglets do the end of shoelaces. Silicon Valley Is Trying to Make Humans Immortal—and Finding Some Success 2015-03-05T05:00:00Z Once I had my own lab at the University of California, Berkeley, I extended the telomere research to yeast, collaborating with Jack Szostak at Harvard Medical School in Boston, Massachusetts. Q&A: End-game winner : Nature : Nature Publishing Group 2015-10-20T04:00:00Z As cells divide, their telomeres get shorter, and this change probably plays a role in aging. In Short-Lived Fish, Secrets to Aging 2015-02-27T05:00:00Z In all, the study team spent 13 years tracking telomere measurements among nearly 800 people. Age-Linked Structures on DNA May Also Hint at Cancer Risk 2015-05-05T04:00:00Z These lifestyle changes may increase telomerase and lengthen telomeres, the ends of our chromosomes that control aging on a cellular level. To Empower Is Not to Blame 2014-12-18T05:00:00Z In young bodies, an enzyme called telomerase keeps telomeres healthy and stable; in older bodies, levels of telomerase drop, telomeres shorten, and the chromosomes begin to fray. Silicon Valley Is Trying to Make Humans Immortal—and Finding Some Success 2015-03-05T05:00:00Z Moving to the University of California San Francisco with its medical school has led me towards all sorts of systems-wide questions around human health and telomeres. Q&A: End-game winner : Nature : Nature Publishing Group 2015-10-20T04:00:00Z And it remains unclear whether or not preserved telomeres actually prolong survival in cancer patients; or in anyone for that matter. Changing Our DNA Through Mind Control? 2014-12-16T05:00:00Z For every point higher that a woman’s diet scored, her telomere length corresponded with about 1.5 years less of aging, the researchers found. Mediterranean diet is tied to improvements in cell aging 2014-12-08T05:00:00Z This is not to say that eating a Mediterranean diet lengthens the telomeres – just that it prevents them from shrinking as fast. A Link Between A Mediterranean Diet And A Long Life 2014-12-03T05:00:00Z Experts believe telomere length offers a window on cellular ageing. Med diet 'keeps us genetically young' 2014-12-02T05:00:00Z After adjusting for other factors, the researchers concluded that telomeres aged more slowly for every point a person went up on the scale. Could a 'Mediterranean' Diet Extend Your Life? 2014-12-02T05:00:00Z Shortened telomeres aren't known to cause a specific disease per se, but they do whither with age and are shorter in people with cancer, diabetes, heart disease and high stress levels. Changing Our DNA Through Mind Control? 2014-12-16T05:00:00Z For example, two women with a three-point difference in their diet scores would show, on average, a 4.5-year difference in aging in their telomeres. Mediterranean diet is tied to improvements in cell aging 2014-12-08T05:00:00Z We do things every day that contribute to oxidative stress and inflammation: Smoking, being obese, and eating a high-sugar diet are all linked to shorter telomeres. A Link Between A Mediterranean Diet And A Long Life 2014-12-03T05:00:00Z The researchers looked at tiny structures called telomeres that safeguard the ends of our chromosomes, which store our DNA code. Med diet 'keeps us genetically young' 2014-12-02T05:00:00Z Researchers found that the regimen -- rich in whole grains, vegetables, fruits, legumes, nuts, fish and olive oil -- appears to be associated with longer telomere length, which are indicators of slower aging. Could a 'Mediterranean' Diet Extend Your Life? 2014-12-02T05:00:00Z The biologic benefits of meditation in particular extend well beyond telomere preservation. Changing Our DNA Through Mind Control? 2014-12-16T05:00:00Z No one food in the diet stood out as lengthening telomeres. Mediterranean diet is tied to improvements in cell aging 2014-12-08T05:00:00Z Why would a Mediterranean diet protect the telomere from shrinking? A Link Between A Mediterranean Diet And A Long Life 2014-12-03T05:00:00Z The new study, published in The BMJ, finds that women who more closely followed a Mediterranean diet had longer telomeres on the end of their chromosomes. No, The Mediterranean Diet Won't Help You Live Forever 2014-12-02T05:00:00Z According to geneticists, telomeres prevent chromosomes from fraying and scrambling the genetic codes they contain. Could a 'Mediterranean' Diet Extend Your Life? 2014-12-02T05:00:00Z When the telomere gets too short, the cell’s number is up. Want to Live Forever? These Men Say They Can Help 2014-12-02T05:00:00Z The researchers measured the women’s telomere length at only one point in time and did not look at whether changes in diet may influence telomere length as time goes on. Mediterranean diet is tied to improvements in cell aging 2014-12-08T05:00:00Z They were particularly interested in a part of the chromosome called the telomere, which is considered a biomarker for aging. A Link Between A Mediterranean Diet And A Long Life 2014-12-03T05:00:00Z They help protect chromosomes and their length is closely correlated to cellular aging: as we age the telomeres in our cells grow shorter. No, The Mediterranean Diet Won't Help You Live Forever 2014-12-02T05:00:00Z "To our knowledge, this is the largest population-based study specifically addressing the association between Mediterranean diet adherence and telomere length in healthy, middle-aged women," the researchers wrote. Could a 'Mediterranean' Diet Extend Your Life? 2014-12-02T05:00:00Z “The only negative association we found,” Leung says, “was between drinking sugary sodas and telomere length, which we attribute to the high sugar content.” The Not-So-Sweet Facts About Soda 2014-11-06T05:00:00Z Moreover, many of the women in the study are of European ancestry, and telomere dynamics may be different in people of other ethnicities. Mediterranean diet is tied to improvements in cell aging 2014-12-08T05:00:00Z The antioxidants in the Mediterranean diet are thought to reduce inflammation and oxidative stress in our cells, possibly leading to a healthier telomere. A Link Between A Mediterranean Diet And A Long Life 2014-12-03T05:00:00Z The new report is based on data from 4,676 women in the Nurses’ Health Study who completed food-frequency questionnaires and who also had their telomere length measured. No, The Mediterranean Diet Won't Help You Live Forever 2014-12-02T05:00:00Z On the other hand, "the Mediterranean diet is filled with antioxidants and anti-inflammatory foods in the form of fruits, vegetables, legumes," she said, and "there is an association with longer telomeres." Could a 'Mediterranean' Diet Extend Your Life? 2014-12-02T05:00:00Z The five-year study found a link between soda intake and shortening of the telomeres, which are caps on the ends of chromosomes directly linked to aging. 16 Unexpected Ways to Add Years to Your Life 2014-11-04T05:00:00Z “To our knowledge, this is the largest population-based study specifically addressing the association between Mediterranean diet adherence and telomere length in healthy, middle-aged women,” De Vivo said in a statement. Mediterranean diet is tied to improvements in cell aging 2014-12-08T05:00:00Z The next step is to look at telomere length in an actual Mediterranean population. A Link Between A Mediterranean Diet And A Long Life 2014-12-03T05:00:00Z In line with much previous research, the researchers found longer telomeres in younger women and nonsmoking women. No, The Mediterranean Diet Won't Help You Live Forever 2014-12-02T05:00:00Z However, the intake of individual food items in the Mediterranean diet was not associated with telomere length, which shows the importance of overall eating patterns on health, De Vivo's team said. Could a 'Mediterranean' Diet Extend Your Life? 2014-12-02T05:00:00Z Simply stand up more during the day and you’ll boost your longevity by increasing the length of your telomeres, according to a study from the British Journal of Sports Medicine. 16 Unexpected Ways to Add Years to Your Life 2014-11-04T05:00:00Z Stress and inflammation may also shorten people’s telomeres, the researchers said in the study, published last week in the journal BMJ. Mediterranean diet is tied to improvements in cell aging 2014-12-08T05:00:00Z She studied telomeres, the caps at the end of chromosomes in every cell in our body, from white blood cells. Soda May Age You As Much As Smoking 2014-10-17T04:00:00Z The main finding of the study was that women with high scores indicating close adherence to the Mediterranean Diet had longer telomeres after adjustment for age. No, The Mediterranean Diet Won't Help You Live Forever 2014-12-02T05:00:00Z Each time a cell replicates, its telomeres shorten. Gerontology: Will you still need me, will you still feed me? : Nature : Nature Publishing Group 2014-10-14T04:00:00Z Researchers found increased telomere length—end caps of chromosomes that link directly to longevity—in the red blood cells of individuals participating in a 6-month physical activity intervention. 16 Unexpected Ways to Add Years to Your Life 2014-11-04T05:00:00Z They found that women with higher scores tended to have longer telomeres than women with lower scores. Mediterranean diet is tied to improvements in cell aging 2014-12-08T05:00:00Z Previous research shows that it’s possible to increase telomere length by as much as 10% over 5 years by stressing less and eating a healthy diet—no soda included. Soda May Age You As Much As Smoking 2014-10-17T04:00:00Z The association remained significant after multiple adjustments for other characteristics likely to influence telomere length, including body mass index, smoking history, exercise, postmenopausal hormone therapy, and hypertension. No, The Mediterranean Diet Won't Help You Live Forever 2014-12-02T05:00:00Z Exactly why some people's telomeres shorten more slowly than other people's is not fully understood, but clues are emerging. Gerontology: Will you still need me, will you still feed me? : Nature : Nature Publishing Group 2014-10-14T04:00:00Z The newest claim is that standing up lengthens your telomeres. Is Sitting At Your Desk Killing You? 2014-09-28T04:00:00Z Future research may determine more specifically which aspects of the diet are associated with increased telomere length, De Vivo said. Mediterranean diet is tied to improvements in cell aging 2014-12-08T05:00:00Z Epel didn’t see any association between telomere length and diet soda intake. Soda May Age You As Much As Smoking 2014-10-17T04:00:00Z But he also points out the limitations of cross-sectional studies and calls for studies that measure “the attrition or shortening of telomeres over time.” No, The Mediterranean Diet Won't Help You Live Forever 2014-12-02T05:00:00Z The chromosomes in van Andel-Schipper's two remaining blood stem cells had much shorter telomeres — caps at the ends that protect the chromosomes from deterioration— than those found in other cells. Gerontology: Will you still need me, will you still feed me? : Nature : Nature Publishing Group 2014-10-14T04:00:00Z Previously, they reported that there was no difference in telomere length between the “exercise” group and the control group. Is Sitting At Your Desk Killing You? 2014-09-28T04:00:00Z Obesity, illness and other conditions can accelerate the shortening, causing cells to age prematurely, while some evidence suggests that healthy lifestyles may preserve telomere length, delaying cell aging. Sit Less, Live Longer? 2014-09-17T04:00:00Z However, this is the first study describing a possible relationship between physical activity and lengthening of telomeres, according to Sjogren. Sit Less, Protect Your DNA and Live Longer? 2014-09-03T04:00:00Z He notes that genetic factors might explain “some of the variation in the association between dietary patterns and telomere length.” No, The Mediterranean Diet Won't Help You Live Forever 2014-12-02T05:00:00Z When telomeres are too short, the cell will either stop replicating and become senescent or it will die. Gerontology: Will you still need me, will you still feed me? : Nature : Nature Publishing Group 2014-10-14T04:00:00Z Just don’t count on it to lengthen your telomeres. Is Sitting At Your Desk Killing You? 2014-09-28T04:00:00Z But perhaps most interesting, there was little correlation between exercise and telomere length. Sit Less, Live Longer? 2014-09-17T04:00:00Z "This study adds a missing snippet to that tale by noting a direct correlation between reduced time sitting each day and increased telomere length," he said. Sit Less, Protect Your DNA and Live Longer? 2014-09-03T04:00:00Z There was no significant association between telomere length and two other dietary patterns, the “prudent” and “Western” dietary patterns. No, The Mediterranean Diet Won't Help You Live Forever 2014-12-02T05:00:00Z If a cell with shortened telomeres continues to replicate it can become abnormal. Gerontology: Will you still need me, will you still feed me? : Nature : Nature Publishing Group 2014-10-14T04:00:00Z So the scientists re-analyzed the data and looked at telomere length as a function of four more measurements. Is Sitting At Your Desk Killing You? 2014-09-28T04:00:00Z Reducing sedentary time had lengthened telomeres, the scientists concluded, while exercising had played little role. Sit Less, Live Longer? 2014-09-17T04:00:00Z More time spent on your feet appears to lengthen bits of DNA called telomeres. Sit Less, Protect Your DNA and Live Longer? 2014-09-03T04:00:00Z “To our knowledge, this is the largest population-based study specifically addressing the association between Mediterranean diet adherence and telomere length in healthy, middle-aged women,” the authors write. No, The Mediterranean Diet Won't Help You Live Forever 2014-12-02T05:00:00Z Elizabeth Blackburn, who won the 2009 Nobel Prize in Physiology or Medicine for her work on telomeres, is taking steps to keep hers long. Gerontology: Will you still need me, will you still feed me? : Nature : Nature Publishing Group 2014-10-14T04:00:00Z “Continually shrinking telomeres. He will age and develop archaic tumours and, eventually, cancer. His body will fail. We haven't seen anything like this since the Mortal Era.” The death of immortality : Nature : Nature Publishing Group 2014-08-12T04:00:00Z If you are unfamiliar with the componentry of your genes, telomeres are the tiny caps on the ends of DNA strands. Sit Less, Live Longer? 2014-09-17T04:00:00Z Although the exercise intervention wasn't linked to longer telomeres, less time sitting was associated with increased telomere length, the researchers found. Sit Less, Protect Your DNA and Live Longer? 2014-09-03T04:00:00Z When cells age, telomeres—tips at the end of chromosomes—shorten. Living a Healthy Life Helps You Age Slower 2014-07-29T04:00:00Z A study involving hundreds of older women found that stressful events are linked to increased shortening of telomeres, the protective caps at the ends of chromosomes that affect how quickly cells age. Healthy Habits May Slow Cellular Signs of Aging, Study Finds 2014-07-29T04:00:00Z The test works by measuring tiny structures at the end of chromosomes called telomeres, which protect them from damage when a cell divides. Leukaemia test developed in Cardiff 2014-07-08T04:00:00Z Meanwhile, in the control group telomeres generally were shorter than they had been six months before. Sit Less, Live Longer? 2014-09-17T04:00:00Z "Long telomeres are good -- long hours sitting, not so much," Katz added. Sit Less, Protect Your DNA and Live Longer? 2014-09-03T04:00:00Z The maintenance of telomeres—the structures of repetitive sequences as the end of a chromatid—is essential to the health of a cell. [Business Office Feature] Targeting Telomeres in Human Disease: Advances and Therapeutic Opportunities 2014-04-29T14:57:10.659Z The women provided blood samples at the beginning and the end of the year for telomere measurement. Healthy Habits May Slow Cellular Signs of Aging, Study Finds 2014-07-29T04:00:00Z For example, the correlation between age and the length of telomeres is less than 0.5. Biomarkers and ageing: The clock-watcher 2014-04-09T17:20:26.613Z Rather, as he writes in the study, “mortality rates declined at higher levels of standing,” suggesting that standing is not sedentary or hazardous, a conclusion with which our telomeres would likely concur. Sit Less, Live Longer? 2014-09-17T04:00:00Z For the study, researchers analyzed the length of telomeres in the blood cells of 49 sedentary and overweight people in their late 60s. Sit Less, Protect Your DNA and Live Longer? 2014-09-03T04:00:00Z Additionally, current research is targeting telomere lengthening mechanisms as a cancer therapy. [Business Office Feature] Targeting Telomeres in Human Disease: Advances and Therapeutic Opportunities 2014-04-29T14:57:10.659Z But women who maintained active lifestyles, ate right and slept well appeared to shrug off the effects of stress, with their telomeres showing no significant additional shortening, the researchers said. Healthy Habits May Slow Cellular Signs of Aging, Study Finds 2014-07-29T04:00:00Z The length of telomeres is often considered to be a biomarker of chronic stress. Stress Alters Children's Genomes 2014-04-07T21:24:00Z In particular, with this experiment, the scientists were interested in whether changes in sedentary time would affect people’s telomeres. Sit Less, Live Longer? 2014-09-17T04:00:00Z “If schizophrenia is associated with accelerated ageing, you would expect that the shortening of telomeres over the five years in schizophrenia would be faster than that in healthy comparison subjects,” he says. Ageing: Live faster, die younger 2014-04-02T17:21:08.997Z As your cells grow older and the telomeres shorten, eventually the cell will no longer replicate. (Hi)stories our bodies tell: Experiencing racism 2014-03-09T11:45:57Z As telomeres become shorter and their structural integrity weakens, cells age and die faster. Healthy Habits May Slow Cellular Signs of Aging, Study Finds 2014-07-29T04:00:00Z Genetic links The link between stressful home environments and telomere length is moderated by genetic variants in pathways that process two chemical transmitters in the brain, serotonin and dopamine, the study found. Stress Alters Children's Genomes 2014-04-07T21:24:00Z And when the scientists compared telomeres, they found that the telomeres in the volunteers who were sitting the least had lengthened. Sit Less, Live Longer? 2014-09-17T04:00:00Z Several small studies have documented shorter telomeres in patients with schizophrenia, but a larger 2013 study failed to replicate these results — in fact they found longer telomeres in people with the disease. Ageing: Live faster, die younger 2014-04-02T17:21:08.997Z Mr. Silvertown’s narrative ends with the newest elements of modern longevity science: telomeres and telomerase, oxidative stress and free-radical dependent repair. Books: Secrets of the Ages 2014-02-24T21:09:27Z The researchers found that these major stress events caused a significantly greater decline in telomere lengths for women who halfheartedly engaged in healthy behaviors. Healthy Habits May Slow Cellular Signs of Aging, Study Finds 2014-07-29T04:00:00Z Although these variants were known to influence chemical responses to stress in the brain, they were not previously linked to telomere length, says Notterman. Stress Alters Children's Genomes 2014-04-07T21:24:00Z In 2009, Jack Szostak shared a Nobel Prize for his part in discovering the role of telomeres, the end bits of... New Solar Cell Material Acts as a Laser As Well 2013-12-04T08:45:00Z In addition, Jeste's team will not only measure telomeres but also record their rate of shortening over time. Ageing: Live faster, die younger 2014-04-02T17:21:08.997Z In 2009, Jack Szostak shared a Nobel Prize for his part in discovering the role of telomeres, the end bits of chromosomes that help ensure genetic information is copied faithfully. [News Focus] The Life Force 2013-12-04T22:55:21.034Z But the same levels of stress caused no greater shortening in the telomeres of women who stayed active, ate healthily and slept well. Healthy Habits May Slow Cellular Signs of Aging, Study Finds 2014-07-29T04:00:00Z In the latest study, the researchers found that the 'sensitizing' variants of these genes protected telomeres in children from nurturing environments, and caused greater telomere damage in children from disadvantaged homes. Stress Alters Children's Genomes 2014-04-07T21:24:00Z The team looked for signs of cell aging by measuring the size of the participants’ telomeres – little “caps” on the ends of chromosomes, which get smaller every time the cell divides. How Depression Can Speed The Aging Process 2013-11-12T18:38:00Z As cells divide, the telomeres get shorter and shorter. Depression 'speeds ageing process' 2013-11-12T09:50:08Z Basically, the shorter your telomeres, the shorter your lifespan. Does Intermittent Fasting Work? 2013-11-01T14:10:00Z A telomere is like the heat-shield of a spacecraft; it protects the actual spacecraft and absorbs the damage instead. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z DCC-M0-like genomes have few and atypical copy number alterations, no signs of telomere crisis, subchromosomal loss that occurs before whole chromosome change and few point mutations. Selection and adaptation during metastatic cancer progression 2013-09-18T17:22:42.817Z The men's telomere length was measured at the start and then five years later. Can we reverse ageing? 2013-09-17T01:37:52Z She says telomere length does not consistently predict other key outcomes such as death risk. Depression 'speeds ageing process' 2013-11-12T09:50:08Z Just as the plastic casings protect the end shoestrings, telomeres protect the ends of your chromosomes. Does Intermittent Fasting Work? 2013-11-01T14:10:00Z The presence of a telomere, shown in pink, allows the DNA to be protected as the telomere gets shortened instead. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z "Our genes, and our telomeres, are a predisposition, but they are not necessarily our fate." Health kick 'reverses cell ageing' 2013-09-17T01:37:47Z Shorter telomeres are associated with a range of age-related diseases including cancer, heart disease and dementia. Can we reverse ageing? 2013-09-17T01:37:52Z Further, it is likely that only a major depressive disorder, not experience of or even a lifetime of mild-to-moderate depressive symptoms, relates to telomere length, she said. Depression 'speeds ageing process' 2013-11-12T09:50:08Z It just so happens that intermittent fasting is a way to increase the length of your telomeres. Does Intermittent Fasting Work? 2013-11-01T14:10:00Z They achieve this by destroying the cellular timekeeper, the telomere. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z The changes related to protective caps at the end of our chromosomes, called telomeres. Health kick 'reverses cell ageing' 2013-09-17T01:37:47Z Rather, the research suggests that comprehensive lifestyle changes - reducing stress, improving diet and moderate exercise - may increase the length of telomeres, the ends of chromosomes that control cell ageing. Can we reverse ageing? 2013-09-17T01:37:52Z The researchers were looking for changes in structures deep inside cells called telomeres. Depression 'speeds ageing process' 2013-11-12T09:50:08Z We noted a correlation between the degree of positive lifestyle change and increase in telomere length when all participants were assessed together, which supports the internal validity of this study. No, Dean Ornish And Elizabeth Blackburn Have Not Discovered The Fountain Of Youth 2013-09-16T22:30:00Z Intriguingly, telomere length is also affected by oxidative stress. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z They measured telomere length at the beginning of their study and again after five years. Health kick 'reverses cell ageing' 2013-09-17T01:37:47Z Secondly, by contrast, globally increasing telomere length in cancer-prone mice actually predisposes to more aggressive cancers. Can we reverse ageing? 2013-09-17T01:37:52Z These visible differences in a measure of cell ageing called telomere length couldn't be explained by other factors, such as whether a person smoked. Depression 'speeds ageing process' 2013-11-12T09:50:08Z But it is far too early to know if measuring telomere length is a good way to assess the value of an intervention. No, Dean Ornish And Elizabeth Blackburn Have Not Discovered The Fountain Of Youth 2013-09-16T22:30:00Z This progressive loss eventually causes the telomeres to lose their ability to protect the ends of chromosomal DNA. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z Also, the significance of the effect of these lifestyle changes on telomere length is actually quite borderline, with only two or three men showing any improvement. Health kick 'reverses cell ageing' 2013-09-17T01:37:47Z Densities for telomere repeats are exaggerated for visual clarity. Oil palm genome sequence reveals divergence of interfertile species in Old and New worlds 2013-08-14T18:20:59.500Z Indeed, telomeres — the tips of our chromosomes — appear to be shorter among those who have experienced early-life adversity, which might be an indicator of accelerated aging. | The Great Divide: Status and Stress 2013-07-27T18:30:23Z Interventions that increase telomere length are worth further study, but it will be extremely difficult to prove a link between the effect on telomeres of an intervention and an improvement in outcomes. No, Dean Ornish And Elizabeth Blackburn Have Not Discovered The Fountain Of Youth 2013-09-16T22:30:00Z The immortalization of cancer cells by telomere maintenance therefore represents an essential step in tumor progression. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z Experts agree that telomere shortening is unlikely to be the sole explanation for human ageing. Health kick 'reverses cell ageing' 2013-09-17T01:37:47Z Densities for telomere repeats are exaggerated for visual clarity. Oil palm genome sequence reveals divergence of interfertile species in Old and New worlds 2013-08-14T18:20:59.500Z The POT1 gene binds to DNA at the telomere, the region at the tip of a chromosome, and protects it from damage. Genetics: Written in blood 2013-06-26T17:20:50.130Z The senior author of the paper is Elizabeth Blackburn, who won the Nobel Prize for her discovery of telomeres and their significance. No, Dean Ornish And Elizabeth Blackburn Have Not Discovered The Fountain Of Youth 2013-09-16T22:30:00Z Without telomeres, each time a cell divides our genomes would progressively lose information because the chromosomes would get shorter and shorter. The Hallmarks of Cancer: 4 - Limitless Replicative Potential 2013-10-10T19:45:47.683Z Time naturally shortens telomeres because whenever a cell divides, a portion of the telomere is not replicated. Chromosome Caps Offer Clues to Aging 2013-04-01T12:15:00.357Z Of course, you don’t want to lose your telomeres either, as then you’d start losing regular DNA. Increasing telomerase to save you from stress 2013-03-25T12:45:05.043Z Overall, people with shorter telomeres in a specific type of blood cell – a CD8CD28 T-cell that is critical for eliminating infections — were more likely to succumb to infections. Prone to Colds? Blame This Tiny Bit of Your DNA 2013-02-22T22:50:22Z The investigators reported that change in telomere length was significantly related to the degree of lifestyle change regardless of the study group. No, Dean Ornish And Elizabeth Blackburn Have Not Discovered The Fountain Of Youth 2013-09-16T22:30:00Z Titia de Lange of Rockefeller University studies telomeres, the protective ends of the chromosomes that contain human DNA. Billionaires Anoint Biogeeks 2013-02-20T16:04:30Z In a study co-authored by Hassett that appeared in the October 2012 issue of the Journal of Pain, higher levels of chronic pain in women with fibromyalgia were strongly associated with shortened telomeres. Chromosome Caps Offer Clues to Aging 2013-04-01T12:15:00.357Z To know about telomerase you have to know about telomeres. Increasing telomerase to save you from stress 2013-03-25T12:45:05.043Z And individuals with shorter telomeres were more likely to get respiratory infections, although this was only true among those aged 21 or older. Prone to Colds? Blame This Tiny Bit of Your DNA 2013-02-22T22:50:22Z Further, as expected, telomere shortening was independently predicted by age, but the effect of the lifestyle program was independent of age and worked in the opposite direction. No, Dean Ornish And Elizabeth Blackburn Have Not Discovered The Fountain Of Youth 2013-09-16T22:30:00Z The findings suggest how long telomeres are may play a role in disease susceptibility in younger people as well, Cohen said. Cold symptoms may have chromosome link 2013-02-20T02:56:13Z But at the end of every chromosome in our body lies a long chain of repetitive DNA called a telomere, which acts as a protective cap. Chromosome Caps Offer Clues to Aging 2013-04-01T12:15:00.357Z So you have telomeres, nonsense DNA strands which get slightly shorter with every replication of the DNA. Increasing telomerase to save you from stress 2013-03-25T12:45:05.043Z |
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