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单词 suppressor gene
例句 suppressor gene
Research into HPV eventually uncovered how Henrietta’s cancer started: HPV inserted its DNA into the long arm of her eleventh chromosome and essentially turned off her p 5 3 tumor suppressor gene. The Immortal Life of Henrietta Lacks 2010-02-02T00:00:00Z
Explain the difference between a proto-oncogene and a tumor suppressor gene. Concepts of Biology 2013-04-25T00:00:00Z
For example, changes in the activity of the tumor suppressor gene p53 can result in cancer. Biology for AP Courses 2022-06-09T00:00:00Z
On the other hand, a dysfunctional tumor suppressor gene may fail to provide the cell with a necessary stop signal, also resulting in unwanted cell division and proliferation. Anatomy and Physiology 2013-06-19T00:00:00Z
That led him to his “two-hit” hypothesis, and his insight that cancer sometimes results not from a particular cause, but rather from the disabling of something known today as the tumor suppressor gene. Dr. Alfred G. Knudson, the ‘Mendel of Cancer Genetics,’ Dies at 93 2016-07-14T04:00:00Z
In this study, researchers zeroed in on a specific variant in a tumor suppressor gene that is mutated and activated in most cancers. Gene May Explain Higher Rates of Some Cancers in Black People 2016-03-31T04:00:00Z
Nearly 25 years ago, Dr. Brash and his co-workers reported that UV light induced mutations in the critically important tumor suppressor gene called p53. With Summer Sun Come Signs of Danger 2015-06-29T04:00:00Z
The most studied tumor suppressor gene is p53, which is mutated in over 50 percent of all cancer types. Biology for AP Courses 2022-06-09T00:00:00Z
TET2 is a tumor suppressor gene—so when it becomes defective, it's like disabling the brakes on a runaway car. Mutation Order in Tumor Genes Affects Cancer Outcome 2015-02-11T05:00:00Z
Mutations of the tumour suppressor gene TP53 are abundant in cancers of all kinds, and frequently appear in the lung cancers of smokers. Public health: A burning issue : Nature : Nature Publishing Group 2014-09-09T04:00:00Z
However, comparable numbers of amplifications and deletions were observed, making it difficult to conclude from the data in ref. that acts as a tumour suppressor gene in hepatocellular carcinoma. Corrigendum: Ptpn11 deletion in a novel progenitor causes metachondromatosis by inducing hedgehog signalling 2014-04-16T17:22:46.125Z
Mutations in the tumour suppressor gene APC, for instance, are common in gastrointestinal malignances such as colorectal cancer, probably owing to the importance of WNT-signalling pathways in intestinal epithelial homeostasis. The causes and consequences of genetic heterogeneity in cancer evolution 2013-09-18T17:22:16.487Z
Given the non-optimal conditions under which the parent cell reproduced, it is likely that the daughter cells will have acquired other mutations in addition to the faulty tumor suppressor gene. Biology for AP Courses 2022-06-09T00:00:00Z
The samples were also tested for the expression of the p53 gene—a tumour suppressor gene that produces a protein to help counteract cell damage. ?E-waste Pollution? Threat to Human Health 2011-06-01T15:01:00Z
Also of note is that the gene involved in the FANCD1 complementation group is BRCA2, a tumor suppressor gene involved in DNA repair and often mutated in breast cancer. Doctor, what's wrong with my child?--What Guido Fanconi taught us about chemotherapy 2011-02-14T14:15:00.247Z
“This is a tumor suppressor gene,” says Nickolas Papadopoulos, a cancer geneticist at Johns Hopkins University in Baltimore, who worked on the study in Science. Mutated Gene Cited in Some Ovarian Cancers 2010-09-09T14:43:00Z
A so-called tumor suppressor gene called retinoblastoma, or Rb, helps control this process in mammals. Plain cells turned into beating heart cells: study 2010-08-05T17:21:00Z
The collective function of the best- understood tumor suppressor gene proteins, Rb, p53, and p21, is to put up a roadblock to cell cycle progression until certain events are completed. Biology for AP Courses 2022-06-09T00:00:00Z
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