| 单词 | acetylation |
| 例句 | In conclusion, using an unbiased and global genetic screen combined with cellular phenotyping, the team uncovered a general function for N-terminal acetylation in protecting proteins from degradation in human cells. Researchers solve protein mystery 2023-10-27T04:00:00Z The study, published in the journal Nature Metabolism, uncovers the critical role of MOF in maintaining mitochondrial integrity through a process called protein acetylation. Epigenetic regulator MOF drives mitochondrial metabolism 2023-10-09T04:00:00Z On the other hand, histone acetylation results in loose packing of nucleosomes, allowing transcription factors to bind to DNA. Biology for AP Courses 2022-06-09T00:00:00Z Histone acetylation is a well-known lever for genes controlling memory formation and consolidation. EpiVario: mixing psychotherapy and small-molecule drugs 2020-06-29T04:00:00Z The authors also compared lysine lactylation and acetylation, finding lactylation at many genes that lack acetylation — suggesting distinct roles for the two modifications. Histone lactylation links metabolism and gene regulation 2019-10-22T04:00:00Z The impact of these pathways on longevity and motility in aged individuals underscores the vital role of protein N-terminal acetylation. Researchers solve protein mystery 2023-10-27T04:00:00Z The findings shed light on the specific machinery responsible for regulating protein acetylation of mitochondrial proteins and deepens the understanding of how cells fine-tune their metabolic output. Epigenetic regulator MOF drives mitochondrial metabolism 2023-10-09T04:00:00Z The UV rays could cause phosphorylation and acetylation of the DNA and histones which could alter the transcriptional capabilities of the DNA. Biology for AP Courses 2022-06-09T00:00:00Z The acetylation of histones is similarly involved in the crosstalk between the microbiota and the innate arm of the immune system. The microbiome and innate immunity : Nature : Nature Publishing Group 2016-07-05T04:00:00Z Potential gene expression changes caused by DNA replication–driven gene dosage effects are buffered by histone acetylation. Expression homeostasis during DNA replication | Science 2016-03-03T05:00:00Z Biochemical, cell biology and proteomics experiments demonstrated that N-terminal acetylation acts as shield to protect many proteins from protein degradation. Researchers solve protein mystery 2023-10-27T04:00:00Z Very little is known about how acetylation of mitochondrial proteins alters their biochemical properties and functional consequences. Epigenetic regulator MOF drives mitochondrial metabolism 2023-10-09T04:00:00Z Drugs maintain DNA methylation and acetylation to silence unimportant genes in cancer cells. Biology for AP Courses 2022-06-09T00:00:00Z When a treatment resulted in greater histone acetylation in the ants, minors revved up foraging and even started taking on the job of the scout caste, looking in new places for food. Bipolar drug turns foraging ants into scouts 2015-12-31T05:00:00Z Potential gene expression changes caused by DNA replication–driven gene dosage effects are buffered by histone acetylation. Expression homeostasis during DNA replication | Science 2016-03-03T05:00:00Z Proteins lacking N-terminal acetylation were recognized by the cellular degradation machinery. Researchers solve protein mystery 2023-10-27T04:00:00Z The implications of this discovery are far-reaching, suggesting that the balance of protein acetylation in mitochondria may be a critical factor in protecting cells from metabolic catastrophe. Epigenetic regulator MOF drives mitochondrial metabolism 2023-10-09T04:00:00Z In new seedlings, histone methylations are present; upon cold exposure, acetylation occurs. Biology for AP Courses 2022-06-09T00:00:00Z Moreover, the work shows the power of histone acetylation, in addition to methylation. Bipolar drug turns foraging ants into scouts 2015-12-31T05:00:00Z “That result started to convince me that the acetylation of histones may be a direct cause of gene activation,” he says. Epigenetics: The genome unwrapped : Nature : Nature Publishing Group 2015-12-01T05:00:00Z Allelic histone acetylation at enhancers is highly specific to individual genotypes, and often occurs near sequence variants that alter transcription factor binding, suggesting cis-acting sequence drivers for at least a subset of these regions61, 72. Integrative analysis of 111 reference human epigenomes : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Shown to the right is the level of mRNA-seq data for each allele of the FAM65B gene, the level of histone acetylation at the allelic enhancer bait region. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z The UV rays can cause methylation and acetylation of histones making the DNA more tightly packed and leading to inaccessibility. Biology for AP Courses 2022-06-09T00:00:00Z Functional magnetic resonance imaging studies showed that within the hippocampal formation, dysfunction was selectively observed in the DG, and this corresponded to a regionally selective decrease in histone acetylation. [Research Articles] Molecular Mechanism for Age-Related Memory Loss: The Histone-Binding Protein RbAp48 2013-08-28T18:25:07.930Z That suggests it is the acetylation of H3 histones rather than the methylation of DNA itself that is creating the effect. Epigenetics and health: Grandma’s curse 2012-11-01T16:03:12Z Perhaps, they thought, if acetylation were increased, NUT–BRD4 would be so busy 'reading' elsewhere that it would overlook the region that was causing cells to become cancerous. Cancer research: Open ambition 2012-08-08T17:20:31.413Z To systematically study allelic enhancers, we combined several enhancer marks to obtain a combined acetylation bam file. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z Histone proteins that surround that region lack the acetylation modification that is present when the genes are expressed in normal cells. Biology for AP Courses 2022-06-09T00:00:00Z Nicotine loosens chromatin, a complex material in which DNA is packaged up by histones and other proteins, by enhancing a process called histone acetylation, catalyzed by acetylase enzymes. Smoking Stokes Cocaine Cravings 2011-11-03T21:15:10.113Z The pine goes into the reactor for acetylation at Accsys Arnhem plant Softwoods such as pine are traditionally less stable, less durable and more prone to bleaching than their more stoic sisters. Rice house 2011-05-06T10:19:08Z Therefore, glucose is the primary source of the acetyl units used for both amino sugar biosynthesis and nuclear protein acetylation. Branched tricarboxylic acid metabolism in Plasmodium falciparum 2011-01-19T18:25:11.737Z Shown to the right is the level of mRNA-seq data for each allele of the FAM65B gene, the level of histone acetylation at the allelic enhancer bait region. Chromatin architecture reorganization during stem cell differentiation : Nature : Nature Publishing Group 2015-02-17T05:00:00Z The traffic signs on this microtubule network are chemical additions such as acetylation marks. Study Identifies Critical 'Traffic Engineer' of the Nervous System 2010-09-09T14:26:00Z If this hydrate survived the acetylation it would of course affect the empirical composition, i.e. chiefly the carbon percentage, of the product. Researches on Cellulose 1895-1900 Put them through a process known as acetylation, however, and that could change everything. Rice house 2011-05-06T10:19:08Z After acetylation is complete, therefore, the operations must be conducted as rapidly as possible. Nitro-Explosives: A Practical Treatise The furfural constants of the lignocellulose are unaffected by the acetylation and condensation. Researches on Cellulose 1895-1900 At the same time the internal condensation noticed in the acetylation of the jute appears not to occur in the case of the benzoate. Researches on Cellulose 1895-1900 |
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