The most popular ones include: (1) Cholinergic hypothesis, which states that a possible cause of Alzheimer's is the loss of central cholinergic neurons and ensuing deficiency of acetylcholine, a neurotransmitter involved in memory and learning.

（1）胆碱能假说，它指出了一个可能的原因阿尔茨海默氏症的症状是中枢胆碱能神经元的丧失和随之而来的乙酰胆碱的缺乏，乙酰胆碱是一种参与记忆和学习的神经递质。