Individuals with tuberous sclerosis can develop renal tumors called angiomyolipomas.

结节性硬化症可发展为肾肿瘤，称为血管平滑肌脂肪瘤。

Treatment of tuberous sclerosis is focused on symptoms.

结节性硬化症的治疗主要在于对症治疗。

On top of that the lifetime risk of cancer is increased in individuals with tuberous sclerosis.

除此之外，结节性硬化症患者一生中患癌症的风险也会增加。

Individuals with tuberous sclerosis have a mutation in either the gene TSC1 or TSC2, and these mutations have an autosomal dominant inheritance pattern.

结节性硬化症患者的TSC1或TSC2基因发生了突变，为常染色体显性遗传。

Symptoms of tuberous sclerosis are often related to the hamartomas in the brain which cause problems like seizures, learning difficulties, and cognitive deficits.

结节性硬化症的症状通常与大脑中的错构瘤有关，导致癫痫、学习困难、认知障碍等。

These developmental masses happen frequently in patients that also have tuberous sclerosis —a genetic disorder causing these non-cancerous masses to form in various tissues.

这些肿块通常发生在患有结节性硬化病患者身上；结节性硬化病是一种各类组织中形成非恶性肿瘤的遗传病。